Medicine by Alexandros G. Sfakianakis

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

High-speed videolaryngoscopy in early glottic carcinoma patients following transoral CO2 LASER cordectomy.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:51

Hypomagnesemia and survival in patients with head and neck cancers who received primary concurrent chemoradiation.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:51

Neuronavigated rTMS inhibition of right pars triangularis anterior in stuttering: Differential effects on reading and speaking
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:08

Capacidad predictiva de la expresión de IL-8 en pacientes con carcinomas escamosos de cabeza y cuello tratados con radioterapia o quimio-radioterapia
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:08

Fifteen-Year Follow-Up of Stapedotomy Patients: Audiological Outcomes and Associated Factors in a Middle Income Country
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:08

Successful cochlear implantation in a patient with Epstein syndrome during long-term follow-up
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:08

Subtotal functional sialoadenectomy vs four‐duct ligation for the treatment of drooling in neurologically impaired children: Long‐term follow‐up
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:07

Role of monoclonal antibody drugs in the treatment of COVID-19.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:45

Transanal minimally invasive surgery vs endoscopic mucosal resection for rectal benign tumors and rectal carcinoids: A retrospective analysis.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:44

Impact of mTOR gene polymorphisms and gene-tea interaction on susceptibility to tuberculosis.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:44

Establishment and validation of a nomogram to predict the risk of ovarian metastasis in gastric cancer: Based on a large cohort.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:43

Predictive factors for early clinical response in community-onset Escherichia coli urinary tract infection and effects of initial antibiotic treatment on early clinical response.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:43

Managing acute appendicitis during the COVID-19 pandemic in Jiaxing, China.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:43

Clinical application of combined detection of SARS-CoV-2-specific antibody and nucleic acid.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:42

Clinical study on the surgical treatment of atypical Lisfranc joint complex injury.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:41

Percutaneous radiofrequency ablation is superior to hepatic resection in patients with small hepatocellular carcinoma.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:41

Prolonged prothrombin time at admission predicts poor clinical outcome in COVID-19 patients.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:41

Application of medial column classification in treatment of intra-articular calcaneal fractures.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:40

Meta-analysis reveals an association between acute pancreatitis and the risk of pancreatic cancer.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:40

Left atrial appendage aneurysm: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:40

Twenty-year survival after iterative surgery for metastatic renal cell carcinoma: A case report and review of literature.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:40

Primary rhabdomyosarcoma: An extremely rare and aggressive variant of male breast cancer.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:39

Bladder stones in a closed diverticulum caused by Schistosoma mansoni: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:39

Cutaneous ciliated cyst on the anterior neck in young women: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:39

Extremely rare case of successful treatment of metastatic ovarian undifferentiated carcinoma with high-dose combination cytotoxic chemotherapy: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:39

Eight-year follow-up of locally advanced lymphoepithelioma-like carcinoma at upper urinary tract: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:38

Ascaris-mimicking common bile duct stone: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:38

Acute amnesia during pregnancy due to bilateral fornix infarction: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:38

Spontaneous resolution of idiopathic intestinal obstruction after pneumonia: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:37

Successful pregnancy after protective hemodialysis for chronic kidney disease: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:37

Rapid remission of refractory synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome in response to the Janus kinase inhibitor tofacitinib: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:37

Percutaneous fixation of neonatal humeral physeal fracture: A case report and review of the literature.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:37

Application of ozonated water for treatment of gastro-thoracic fistula after comprehensive esophageal squamous cell carcinoma therapy: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:36

Severe fundus lesions induced by ocular jellyfish stings: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:36

Germinomas of the basal ganglia and thalamus: Four case reports.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:36

Gastrointestinal bleeding caused by jejunal angiosarcoma: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:36

Severe hyperlipemia-induced pseudoerythrocytosis – Implication for misdiagnosis and blood transfusion: A case report and literature review.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:35

Therapy-related acute promyelocytic leukemia with FMS-like tyrosine kinase 3-internal tandem duplication mutation in solitary bone plasmacytoma: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:35

High expression of squamous cell carcinoma antigen in poorly differentiated adenocarcinoma of the stomach: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:35

Αφαίρεση διαφημίσεων


Metastasis of esophageal squamous cell carcinoma to the thyroid gland with widespread nodal involvement: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:35

Novel brachytherapy drainage tube loaded with double 125I strands for hilar cholangiocarcinoma: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:34

Primary hepatic myelolipoma: A case report and review of the literature.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:34

Endoscopic palliative resection of a giant 26-cm esophageal tumor: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:34

Resorption of upwardly displaced lumbar disk herniation after nonsurgical treatment: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:34

Intravesically instilled gemcitabine-induced lung injury in a patient with invasive urothelial carcinoma: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:33

Solitary hepatic lymphangioma mimicking liver malignancy: A case report and literature review.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:33

Intraosseous venous malformation of the maxilla after enucleation of a hemophilic pseudotumor: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:33

Bochdalek hernia masquerading as severe acute pancreatitis during the third trimester of pregnancy: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:32

Localized primary gastric amyloidosis: Three case reports.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:32

Parathyroid adenoma combined with a rib tumor as the primary disease: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:31

Σήμανση της παραπάνω ενότητας ως αναγνωσμένης

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Fifteen-Year Follow-Up of Stapedotomy Patients: Audiological Outcomes and Associated Factors in a Middle Income Country
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:08

Successful cochlear implantation in a patient with Epstein syndrome during long-term follow-up
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:08

Subtotal functional sialoadenectomy vs four‐duct ligation for the treatment of drooling in neurologically impaired children: Long‐term follow‐up
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:07

Role of monoclonal antibody drugs in the treatment of COVID-19.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:45

Transanal minimally invasive surgery vs endoscopic mucosal resection for rectal benign tumors and rectal carcinoids: A retrospective analysis.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:44

Impact of mTOR gene polymorphisms and gene-tea interaction on susceptibility to tuberculosis.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:44

Establishment and validation of a nomogram to predict the risk of ovarian metastasis in gastric cancer: Based on a large cohort.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:43

Managing acute appendicitis during the COVID-19 pandemic in Jiaxing, China.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:43

Predictive factors for early clinical response in community-onset Escherichia coli urinary tract infection and effects of initial antibiotic treatment on early clinical response.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:43

Αφαίρεση διαφημίσεων


Clinical application of combined detection of SARS-CoV-2-specific antibody and nucleic acid.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:42

Percutaneous radiofrequency ablation is superior to hepatic resection in patients with small hepatocellular carcinoma.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:41

Prolonged prothrombin time at admission predicts poor clinical outcome in COVID-19 patients.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:41

Clinical study on the surgical treatment of atypical Lisfranc joint complex injury.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:41

Application of medial column classification in treatment of intra-articular calcaneal fractures.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:40

Meta-analysis reveals an association between acute pancreatitis and the risk of pancreatic cancer.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:40

Left atrial appendage aneurysm: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:40

Twenty-year survival after iterative surgery for metastatic renal cell carcinoma: A case report and review of literature.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:40

Cutaneous ciliated cyst on the anterior neck in young women: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:39

Primary rhabdomyosarcoma: An extremely rare and aggressive variant of male breast cancer.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:39

Bladder stones in a closed diverticulum caused by Schistosoma mansoni: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:39

Extremely rare case of successful treatment of metastatic ovarian undifferentiated carcinoma with high-dose combination cytotoxic chemotherapy: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:39

Acute amnesia during pregnancy due to bilateral fornix infarction: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:38

Ascaris-mimicking common bile duct stone: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:38

Eight-year follow-up of locally advanced lymphoepithelioma-like carcinoma at upper urinary tract: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:38

Successful pregnancy after protective hemodialysis for chronic kidney disease: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:37

Spontaneous resolution of idiopathic intestinal obstruction after pneumonia: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:37

Rapid remission of refractory synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome in response to the Janus kinase inhibitor tofacitinib: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:37

Percutaneous fixation of neonatal humeral physeal fracture: A case report and review of the literature.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:37

Severe fundus lesions induced by ocular jellyfish stings: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:36

Αφαίρεση διαφημίσεων


Application of ozonated water for treatment of gastro-thoracic fistula after comprehensive esophageal squamous cell carcinoma therapy: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:36

Germinomas of the basal ganglia and thalamus: Four case reports.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:36

Gastrointestinal bleeding caused by jejunal angiosarcoma: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:36

High expression of squamous cell carcinoma antigen in poorly differentiated adenocarcinoma of the stomach: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:35

Therapy-related acute promyelocytic leukemia with FMS-like tyrosine kinase 3-internal tandem duplication mutation in solitary bone plasmacytoma: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:35

Metastasis of esophageal squamous cell carcinoma to the thyroid gland with widespread nodal involvement: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:35

Severe hyperlipemia-induced pseudoerythrocytosis – Implication for misdiagnosis and blood transfusion: A case report and literature review.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:35

Novel brachytherapy drainage tube loaded with double 125I strands for hilar cholangiocarcinoma: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:34

Resorption of upwardly displaced lumbar disk herniation after nonsurgical treatment: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:34

Primary hepatic myelolipoma: A case report and review of the literature.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:34

Endoscopic palliative resection of a giant 26-cm esophageal tumor: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:34

Intravesically instilled gemcitabine-induced lung injury in a patient with invasive urothelial carcinoma: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:33

Solitary hepatic lymphangioma mimicking liver malignancy: A case report and literature review.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:33

Intraosseous venous malformation of the maxilla after enucleation of a hemophilic pseudotumor: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:33

Bochdalek hernia masquerading as severe acute pancreatitis during the third trimester of pregnancy: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:32

Localized primary gastric amyloidosis: Three case reports.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:32

Parathyroid adenoma combined with a rib tumor as the primary disease: A case report.
…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:31

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
PhilosophiesPhilosophies, Vol. 5, Pages 30: Epistemological Framework for Computer Simulations in Building Science Research: Insights from Theory and PracticePhilosophies, Vol. 5, Pages 30: Epistemological Framework for Computer Simulations in Building Science Research: Insights from Theory and Practice Philosophies doi: 10.3390/philosophies5040030 Authors: Amos Kalua James Jones Computer simulations are widely used within the area of building science research. Building science research deals with…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:31

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
International Journal of Molecular SciencesIJMS, Vol. 21, Pages 7828: Evaluation of QSAR Equations for Virtual ScreeningIJMS, Vol. 21, Pages 7828: Evaluation of QSAR Equations for Virtual Screening International Journal of Molecular Sciences doi: 10.3390/ijms21217828 Authors: Jacob Spiegel Hanoch Senderowitz Quantitative Structure Activity Relationship (QSAR) models can inform on the correlation between activities and structure-based molecular descriptors. This information is important for the…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:29

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
International Journal of Molecular SciencesIJMS, Vol. 21, Pages 7848: Heterogeneous Presynaptic Distribution of Munc13 Isoforms at Retinal Synapses and Identification of an Unconventional Bipolar Cell Type with Dual Expression of Munc13 Isoforms: A Study Using Munc13-EXFP Knock-in MiceIJMS, Vol. 21, Pages 7848: Heterogeneous Presynaptic Distribution of Munc13 Isoforms at Retinal Synapses and Identification of an Unconventional Bipolar Cell Type with Dual Expression of Munc13 Isoforms: A Study Using…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:27

Αφαίρεση διαφημίσεων


Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
AntibioticsAntibiotics, Vol. 9, Pages 724: Decontamination of Ti Oxide Surfaces by Using Ultraviolet Light: Hg-Vapor vs. LED-Based IrradiationAntibiotics, Vol. 9, Pages 724: Decontamination of Ti Oxide Surfaces by Using Ultraviolet Light: Hg-Vapor vs. LED-Based Irradiation Antibiotics doi: 10.3390/antibiotics9110724 Authors: Nagore Arroyo-Lamas Unai Ugalde Iciar Arteagoitia C-range Ultraviolet (UVC) mercury (Hg)-vapor lamps have shown the successful decontamination of hydrocarbons and antimicrobial…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:26

Σήμανση της παραπάνω ενότητας ως αναγνωσμένης

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

Role of monoclonal antibody drugs in the treatment of COVID-19.
…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:45

Transanal minimally invasive surgery vs endoscopic mucosal resection for rectal benign tumors and rectal carcinoids: A retrospective analysis.
…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:44

Impact of mTOR gene polymorphisms and gene-tea interaction on susceptibility to tuberculosis.
…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:44

Establishment and validation of a nomogram to predict the risk of ovarian metastasis in gastric cancer: Based on a large cohort.
…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:43

Predictive factors for early clinical response in community-onset Escherichia coli urinary tract infection and effects of initial antibiotic treatment on early clinical response.
…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:43

Managing acute appendicitis during the COVID-19 pandemic in Jiaxing, China.
…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:43

Clinical application of combined detection of SARS-CoV-2-specific antibody and nucleic acid.
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Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:42

Prolonged prothrombin time at admission predicts poor clinical outcome in COVID-19 patients.
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Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:41

Percutaneous radiofrequency ablation is superior to hepatic resection in patients with small hepatocellular carcinoma.
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Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:41

Clinical study on the surgical treatment of atypical Lisfranc joint complex injury.
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Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:41

Application of medial column classification in treatment of intra-articular calcaneal fractures.
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Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:40

Meta-analysis reveals an association between acute pancreatitis and the risk of pancreatic cancer.
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Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:40

Twenty-year survival after iterative surgery for metastatic renal cell carcinoma: A case report and review of literature.
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Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:40

Left atrial appendage aneurysm: A case report.
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Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:40

Bladder stones in a closed diverticulum caused by Schistosoma mansoni: A case report.
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Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:39

Cutaneous ciliated cyst on the anterior neck in young women: A case report.
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Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:39

Extremely rare case of successful treatment of metastatic ovarian undifferentiated carcinoma with high-dose combination cytotoxic chemotherapy: A case report.
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Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:39

Primary rhabdomyosarcoma: An extremely rare and aggressive variant of male breast cancer.
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Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:39

Eight-year follow-up of locally advanced lymphoepithelioma-like carcinoma at upper urinary tract: A case report.
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Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:38

Αφαίρεση διαφημίσεων


Acute amnesia during pregnancy due to bilateral fornix infarction: A case report.
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Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:38

Ascaris-mimicking common bile duct stone: A case report.
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Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:38

Rapid remission of refractory synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome in response to the Janus kinase inhibitor tofacitinib: A case report.
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Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:37

Spontaneous resolution of idiopathic intestinal obstruction after pneumonia: A case report.
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Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:37

Successful pregnancy after protective hemodialysis for chronic kidney disease: A case report.
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Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:37

Percutaneous fixation of neonatal humeral physeal fracture: A case report and review of the literature.
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Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:37

Σήμανση της παραπάνω ενότητας ως αναγνωσμένης

#
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia,

Telephone consultation 11855 int 1193,

Medicine by Alexandros G. Sfakianakis

Association of Delivery Room and Neonatal Intensive Care Unit Intubation, and Number of Tracheal Intubation Attempts with Death or Severe Neurological Injury among Preterm Infants.
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Medicine by Alexandros G.Sfakianakis

09:30

Consensus Recommendations for the Safe Handling of Cytotoxic Agents in Cytotoxic Academic Research Laboratories (CARL).
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Medicine by Alexandros G.Sfakianakis

09:30

Treating relapsed and refractory metastatic germ cell tumours with high-dose chemotherapy with carboplatin and etoposide and autologous haematopoietic stem cell transplantation.
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Medicine by Alexandros G.Sfakianakis

09:30

Multidirectional pattern of hair growth with carflizomib use for multiple myeloma.
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Medicine by Alexandros G.Sfakianakis

09:29

Tyrosine kinase inhibitors in the treatment of metastatic renal cell cancer patients with early cytokine intolerance: TURCOS, a Turkish national, prospective observational study.
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Medicine by Alexandros G.Sfakianakis

09:29

Immunotherapy in gastroesophageal cancers: Current state and future directions.
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Medicine by Alexandros G.Sfakianakis

09:29

Fatal hepatitis B reactivation in a patient receiving chemoradiation for cervical cancer.
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Medicine by Alexandros G.Sfakianakis

09:27

Successful rechallenge of alectinib after remission of severe alectinib-induced interstitial lung disease.
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Medicine by Alexandros G.Sfakianakis

09:26

Chemoimmunotherapy for the salvage treatment of Ewing sarcoma: A case report
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Medicine by Alexandros G.Sfakianakis

09:25

Head and neck cancer patients’ recollection of their clinical characteristics.
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Medicine by Alexandros G.Sfakianakis

09:24

Comparison of the eighth edition of the TNM and Brigham Women’s Hospital staging systems for cutaneous squamous cell carcinoma of the head and neck: a six-year review.
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Medicine by Alexandros G.Sfakianakis

09:24

Summer season sea surface temperature changes in the Aegean Sea based on 30 years (1989–2019) of Landsat thermal infrared data
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Medicine by Alexandros G.Sfakianakis

09:23

Modeling the spatio-temporal dynamics of air pollution index based on spatial Markov chain model
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Medicine by Alexandros G.Sfakianakis

09:23

Low-Dose Triptolide Enhanced Activity of Idarubicin Against Acute Myeloid Leukemia Stem-like Cells Via Inhibiting DNA Damage Repair Response
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Medicine by Alexandros G.Sfakianakis

09:22

Chronic Rhinosinusitis With Nasal Polyps and Asthma.
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Medicine by Alexandros G.Sfakianakis

09:22

Extended nitric oxide analysis in patients with chronic rhinosinusitis with nasal polyps, with or without associated asthma.
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Medicine by Alexandros G.Sfakianakis

09:22

Long-term therapy response to anti-interleukin-5 biologics in severe asthma – a real-life evaluation.
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Medicine by Alexandros G.Sfakianakis

09:21

Management of patients with chronic rhinosinusitis during the COVID-19 pandemic – An EAACI Position Paper.
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Medicine by Alexandros G.Sfakianakis

09:21

Cefiderocol versus high-dose, extended-infusion meropenem for the treatment of Gram-negative nosocomial pneumonia (APEKS-NP): a randomised, double-blind, phase 3, non-inferiority trial.
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Medicine by Alexandros G.Sfakianakis

09:21

Biological characteristics and genome analysis of a novel phage vB_KpnP_IME279 infecting Klebsiella pneumoniae.
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Medicine by Alexandros G.Sfakianakis

09:20

Efficacy of Xyloglucan against Escherichia coli Extraintestinal Urinary Tract Infection: An in vivo Study.
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Medicine by Alexandros G.Sfakianakis

09:20

Decision Making in Patients With Concomitant Otosclerosis and Superior Semicircular Canal Dehiscence: A Systematic Review of the Literature.
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Medicine by Alexandros G.Sfakianakis

09:20

High-frequency semicircular canal deficit affects postural control in hearing-impaired children.
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Medicine by Alexandros G.Sfakianakis

09:19

Congruous Torsional Down Beating Nystagmus in the Third Position of the Semont’s Maneuver in Patients Treated for Canalithiasis of Posterior Semicircular Canal Benign Paroxysmal Positional Vertigo: Its Significance and Prognostic Value.
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Medicine by Alexandros G.Sfakianakis

09:19

Congruous Torsional Down Beating Nystagmus in the Third Position of the Semont’s Maneuver in Patients Treated for Canalithiasis of Posterior Semicircular Canal Benign Paroxysmal Positional Vertigo: Its Significance and Prognostic Value.
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Medicine by Alexandros G.Sfakianakis

09:18

Migration and fate of vestibular melanocytes during development of the human inner ear.
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Medicine by Alexandros G.Sfakianakis

09:18

Pharmacological management of portal hypertension and its complications in children: lessons from adults and opportunities for the future.
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Medicine by Alexandros G.Sfakianakis

09:18

Epidemiology and Comorbidity of Adrenal Cushing’s Syndrome: A Nationwide Cohort Study.
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Medicine by Alexandros G.Sfakianakis

09:11

Dapagliflozin Added to Verinurad Plus Febuxostat Further Reduces Serum Uric Acid in Hyperuricemia: The QUARTZ Study.
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Medicine by Alexandros G.Sfakianakis

09:10

The Effects of Kisspeptin on Brain Response to Food Images and Psychometric Parameters of Appetite in Healthy Men.
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Medicine by Alexandros G.Sfakianakis

09:10

Adolescent Nonalcoholic Fatty Liver Disease and Type 2 Diabetes in Young Adulthood.
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Medicine by Alexandros G.Sfakianakis

09:10

Biochemical remission after cabergoline withdrawal in hyperprolactinemic patients with visible remnant pituitary adenoma.
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Medicine by Alexandros G.Sfakianakis

09:09

Elevated plasma branched-chain amino acid levels correlate with type 2 diabetes-related metabolic disturbances.
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Medicine by Alexandros G.Sfakianakis

09:09

Molecular Imaging Targeting Corticotropin Releasing Hormone Receptor for Corticotropinoma: A Changing Paradigm.
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Medicine by Alexandros G.Sfakianakis

09:09

A significant role of transcription factors E2F in inflammation and tumorigenesis of nasopharyngeal carcinoma.
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Medicine by Alexandros G.Sfakianakis

09:08

Increasing the availability of quality human tissue for research.
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Medicine by Alexandros G.Sfakianakis

09:07

Chemical concentrations in cell culture compartments (C5) – free concentrations.
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Medicine by Alexandros G.Sfakianakis

09:06

Intraoperative auditory brainstem response monitoring during semicircular canal plugging surgery in treatment of Meniere’s disease.
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Medicine by Alexandros G.Sfakianakis

09:06

Estimation of CARE Dose 4D quality reference mAs conversion factors for child to adult reference patient in child protocols on Siemens Symbia SPECT-CT systems.
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Medicine by Alexandros G.Sfakianakis

09:05

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Special subtypes with favorable prognosis in breast cancer: A registry-based cohort study and network meta-analysis.
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Medicine by Alexandros G.Sfakianakis

09:05

Efficacy and safety of systemic induction therapy in initially unresectable locally advanced intrahepatic and perihilar cholangiocarcinoma: A systematic review.
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Medicine by Alexandros G.Sfakianakis

09:05

Molecular docking studies, anti-Alzheimer’s disease, antidiabetic, and anti-acute myeloid leukemia potentials of narcissoside.
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Medicine by Alexandros G.Sfakianakis

09:04

Metastatic Soft Tissue Sarcoma Presenting as a Subcutaneous Facial Mass.
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Medicine by Alexandros G.Sfakianakis

09:04

Predictive Significance of Enhanced Level of Angiogenesis and Tissue Neutrophils for Antrochoanal Polyps Recurrence in Children.
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Medicine by Alexandros G.Sfakianakis

09:04

Coffee in cancer chemoprevention: an updated review.
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Medicine by Alexandros G.Sfakianakis

09:03

Alterations in drug disposition in older adults: a focus on geriatric syndromes.
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Medicine by Alexandros G.Sfakianakis

09:03

Sound therapy for cochlear implant users with tinnitus.
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Medicine by Alexandros G.Sfakianakis

09:03

GPS predicts stability of listening environment characteristics in one location over time among older hearing aid users.
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Medicine by Alexandros G.Sfakianakis

09:02

Subacute ascending myelopathy in adolescent athlete after spinal cord injury: a case report on dynamic complication of spine trauma.
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Medicine by Alexandros G.Sfakianakis

09:02

Rapidly expanding giant neurofibroma of the back with intratumoral hematoma: a case report and literature review.
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Medicine by Alexandros G.Sfakianakis

09:02

Anosmia caused by ischemic olfactory infarction: false alert for COVID-19 infection.
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Medicine by Alexandros G.Sfakianakis

09:01

Intraoperative auditory brainstem response monitoring during semicircular canal plugging surgery in treatment of Meniere’s disease.
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Medicine by Alexandros G.Sfakianakis

09:00

Effects of resistive jaw opening exercise in stroke patients with dysphagia: A double- blind, randomized controlled study.
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Medicine by Alexandros G.Sfakianakis

09:00

Pepsin and oropharyngeal pH monitoring to diagnose patients with laryngopharyngeal reflux.
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Medicine by Alexandros G.Sfakianakis

09:00

Reduction in Hospitalizations for Esophageal Reflux in a Decade with Minimal Increases in Other Functional and Motor Disorders.
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Medicine by Alexandros G.Sfakianakis

09:00

Aerophagia During Infant Feeding Causing Gastroesophageal Reflux Disease like Symptoms.
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Medicine by Alexandros G.Sfakianakis

08:59

Chair-stand exercise improves post-stroke dysphagia.
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Medicine by Alexandros G.Sfakianakis

08:59

Oral hypofunction and its association with frailty in community-dwelling older people.
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Medicine by Alexandros G.Sfakianakis

08:58

MRI- and CT-determined changes of dysphagia / aspiration-related structures (DARS) during and after radiotherapy.
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Medicine by Alexandros G.Sfakianakis

08:57

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Efficacy and safety of traditional Chinese herbal formula combined with western medicine for gastroesophageal reflux disease: A protocol for systematic review and meta-analysis.
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Medicine by Alexandros G.Sfakianakis

08:57

Depressive Symptoms and Suicidal Ideation in Progressive Multiple Sclerosis Compared to Relapsing-Remitting Multiple Sclerosis: Results from a Cross-Sectional Survey.
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Medicine by Alexandros G.Sfakianakis

08:57

Cannabisin D from Sinomenium Acutum Inhibits Proliferation and Migration of Glioblastoma Cells through MAPKs Signaling.
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Medicine by Alexandros G.Sfakianakis

08:56

Establishment of Acquired Cisplatin Resistance in Ovarian Cancer Cell Lines Characterized by Enriched Metastatic Properties with Increased Twist Expression.
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Medicine by Alexandros G.Sfakianakis

08:56

Baseline BMI and BMI variation during first line pembrolizumab in NSCLC patients with a PD-L1 expression ≥ 50%: a multicenter study with external validation.
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Medicine by Alexandros G.Sfakianakis

08:55

Novel Platinum(II) Complex-based Luminescent Probe for Detection of Hypochlorite in Cancer Cells.
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Medicine by Alexandros G.Sfakianakis

08:55

Eosinophil prognostic scores for patients with head and neck squamous cell carcinoma treated with nivolumab.
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Medicine by Alexandros G.Sfakianakis

08:54

The post-progression survival of patients with recurrent or persistent ovarian clear cell carcinoma: results from a randomized phase III study in JGOG3017/GCIG.
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Medicine by Alexandros G.Sfakianakis

08:54

Outcomes of adolescent males with extracranial metastatic germ cell tumors: A report from the Malignant Germ Cell Tumor International Consortium.
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Medicine by Alexandros G.Sfakianakis

08:53

Comparative Effectiveness of Immune Checkpoint Inhibitors in Patients with Platinum-Refractory Advanced Urothelial Carcinoma.
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Medicine by Alexandros G.Sfakianakis

08:53

Clinical complexity of utilizing FGFR inhibitors in cancer therapeutics.
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Medicine by Alexandros G.Sfakianakis

08:46

The nonalcoholic steatohepatitis (NASH) drug development graveyard: established hurdles and planning for future success.
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Medicine by Alexandros G.Sfakianakis

08:46

A case study of foliglurax, the first clinical mGluR4 PAM for symptomatic treatment of Parkinson’s disease: Translational gaps or a failing industry innovation model?
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Medicine by Alexandros G.Sfakianakis

08:46

More Than Smell-COVID-19 Is Associated With Severe Impairment of Smell, Taste, and Chemesthesis.
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Medicine by Alexandros G.Sfakianakis

08:46

Treatment-related leukopenia in anal cancer patients associated with worse outcome: results of a retrospective cohort study.
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Medicine by Alexandros G.Sfakianakis

08:45

A novel model of injured liver ductal organoids to investigate cholangiocyte apoptosis with relevance to biliary atresia
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Medicine by Alexandros G.Sfakianakis

08:41

Efficacy of Tocilizumab in Patients Hospitalized with Covid-19
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Medicine by Alexandros G.Sfakianakis

08:40

Accuracy of a Mobile 2D Imaging System for Body Volume and Subsequent Composition Estimates in a Three-Compartment Model
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Medicine by Alexandros G.Sfakianakis

08:39

Exploring the Molecular Mechanism and Biomarker of Recurrent Spontaneous Abortion Based on RNA Sequencing Analysis.
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Medicine by Alexandros G.Sfakianakis

08:38

Effect of Pentoxifylline on Inflammatory Cytokines, Adequacy of Dialysis, Anemia and Biochemical Markers of Hemodialysis Patients: a Randomized Controlled Trial.
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Medicine by Alexandros G.Sfakianakis

08:37

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Effect of Pentoxifylline on Inflammatory Cytokines, Adequacy of Dialysis, Anemia and Biochemical Markers of Hemodialysis Patients: a Randomized Controlled Trial.
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Medicine by Alexandros G.Sfakianakis

08:32

Risk Interval of Complete Blood Counts May be Closely Associated with Bone Mineral Density in the Elderly Chinese Population.
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Medicine by Alexandros G.Sfakianakis

08:32

Lipid Risk Factors in Vitiligo: Homocysteine the Connecting Link?
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Medicine by Alexandros G.Sfakianakis

08:31

MiR-2467 is a Potential Marker for Prediction of Gestational Diabetes Mellitus in Pregnancy.
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Medicine by Alexandros G.Sfakianakis

08:31

A Comparison of Reproductive Hormones and Biochemical Parameters in Hypothyroid and Euthyroid Postmenopausal Women.
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Medicine by Alexandros G.Sfakianakis

08:31

A Study on the Expression of SPRED1 and PBRM1 (Baf180) and their Clinical Significances in Patients with Gastric Cancer.
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Medicine by Alexandros G.Sfakianakis

08:29

Serum miR-133 as a Potential Biomarker in Acute Cerebral Infarction Patients.
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Medicine by Alexandros G.Sfakianakis

08:28

Significance of Natural Killer Cell Subsets, their Receptors, and Inflammatory Cytokines in Peripheral Blood of Children with Hand, Foot, and Mouth Disease.
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Medicine by Alexandros G.Sfakianakis

08:28

Diagnosis and Treatment of Cirrhosis with Duodenal Variceal Bleeding: a Case Report.
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Medicine by Alexandros G.Sfakianakis

08:28

Fortuitous Discovery of Hereditary Xanthinuria.
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Medicine by Alexandros G.Sfakianakis

08:26

Elevated Serum Levels of Lp-PLA2 and IL-18 are Associated with Progression of Diabetic Foot Ulcers.
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Medicine by Alexandros G.Sfakianakis

08:25

Multiple-Locus Variable-Number Tandem-Repeat Analysis Genotyping of Brucella Isolates from Iran.
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Medicine by Alexandros G.Sfakianakis

08:25

Diagnostic Characteristics of 3-Parameter and 2-Parameter Equations for the Calculation of a Combined Indicator of Vitamin B12 Status to Predict Cobalamin Deficiency in a Large Mixed Patient Population.
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Medicine by Alexandros G.Sfakianakis

08:25

Assessing the Accuracy of Different Glucometers Based on the Laboratory Reference Method.
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Medicine by Alexandros G.Sfakianakis

08:24

Evaluation of Chromogenic Factor VIII Assay Compared with One-Stage Clotting Assay.
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Medicine by Alexandros G.Sfakianakis

08:24

MiR-429 and MiR-143-3p Function as Diagnostic and Prognostic Markers for Osteosarcoma.
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Medicine by Alexandros G.Sfakianakis

08:23

Genetic Diversity of OXA-like Genes in Multidrug-Resistant Acinetobacter baumannii Strains from ICUs.
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Medicine by Alexandros G.Sfakianakis

08:23

#
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia,

Telephone consultation 11855 int 1193,

Medicine by Alexandros G. Sfakianakis

Impact of concomitant systemic treatments on toxicity and intracerebral response after stereotactic radiotherapy for brain metastases
…

Medicine by Alexandros G. Sfakianakis

09:40

A novel nomogram to predict the overall survival in esthesinoeroblastoma
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Medicine by Alexandros G. Sfakianakis

09:40

Clinical characteristics and prognostic implications of BRCA-associated tumors in males: a pan-tumor survey
…

Medicine by Alexandros G. Sfakianakis

09:39

Limb salvage versus amputation in patients with osteosarcoma of the extremities: an update in the modern era using the National Cancer Database
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Medicine by Alexandros G. Sfakianakis

09:39

YB-1 transferred by gastric cancer exosomes promotes angiogenesis via enhancing the expression of angiogenic factors in vascular endothelial cells
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Medicine by Alexandros G. Sfakianakis

09:39

USP6NL mediated by LINC00689/miR-142-3p promotes the development of triple-negative breast cancer
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Medicine by Alexandros G. Sfakianakis

09:39

Analyses of the local control of pulmonary Oligometastases after stereotactic body radiotherapy and the impact of local control on survival
…

Medicine by Alexandros G. Sfakianakis

09:39

Analysis of the role of the human papillomavirus 16/18 E7 protein assay in screening for cervical intraepithelial neoplasia: a case control study
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Medicine by Alexandros G. Sfakianakis

09:38

CKD-5, a novel pan-histone deacetylase inhibitor, synergistically enhances the efficacy of sorafenib for hepatocellular carcinoma
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Medicine by Alexandros G. Sfakianakis

09:38

Detection of MCM5 as a novel non-invasive aid for the diagnosis of endometrial and ovarian tumours
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Medicine by Alexandros G. Sfakianakis

09:38

Effect of sarcopenia on short- and long-term outcomes in patients with gastric neuroendocrine neoplasms after radical gastrectomy: results from a large, two-institution series
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Medicine by Alexandros G. Sfakianakis

09:37

Biomarker exploration of microRNA-203 as a promising substrate for predicting poor survival outcome in colorectal cancer
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Medicine by Alexandros G. Sfakianakis

09:37

Impact of pre-existing cardiovascular disease on treatment patterns and survival outcomes in patients with lung cancer
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Medicine by Alexandros G. Sfakianakis

09:37

CircRNAs as potential biomarkers for the clinicopathology and prognosis of glioma patients: a meta-analysis
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Medicine by Alexandros G. Sfakianakis

09:37

Inducing multiple antibodies to treat squamous cell esophageal carcinoma
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Medicine by Alexandros G. Sfakianakis

09:29

Ovarian cancer cells direct monocyte differentiation through a non-canonical pathway
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Medicine by Alexandros G. Sfakianakis

09:28

Presence of dynapenia and association with anthropometric variables in cancer patients
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Medicine by Alexandros G. Sfakianakis

09:28

A Swedish Nationwide prospective study of oncological and reproductive outcome following fertility-sparing surgery for treatment of early stage epithelial ovarian cancer in young women
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Medicine by Alexandros G. Sfakianakis

09:28

Discovering the molecular differences between right- and left-sided colon cancer using machine learning methods
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Medicine by Alexandros G. Sfakianakis

09:28

Disseminated intraosseous Kaposi’s sarcoma: A rare manifestation of HIV/AIDS
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Medicine by Alexandros G. Sfakianakis

09:27

The Combined Use of SBRT and Immunotherapy—a Literature Review
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Medicine by Alexandros G. Sfakianakis

09:26

Combined Inhibition of EGFR and VEGF Pathways in Patients with EGFR-Mutated Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis
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Medicine by Alexandros G. Sfakianakis

09:26

How Should We Approach Locally Advanced Squamous Cell Carcinoma of Head and Neck Cancer Patients Ineligible for Standard Non-surgical Treatment?
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Medicine by Alexandros G. Sfakianakis

09:26

Isocitrate Dehydrogenase, Patient-Reported Outcomes, and Cognitive Functioning of Glioma Patients: a Systematic Review
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Medicine by Alexandros G. Sfakianakis

09:26

The Value of Virtual Chromoendoscopy in the Workup of Patients with Head and Neck Squamous Cell Carcinoma
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Medicine by Alexandros G. Sfakianakis

09:26

Extended Endocrine Therapy for Early-Stage Breast Cancer: How Do We Decide?
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Medicine by Alexandros G. Sfakianakis

09:25

Synovial Sarcoma: A Complex Disease with Multifaceted Signaling and Epigenetic Landscapes
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Medicine by Alexandros G. Sfakianakis

09:25

Access to Therapy for Acute Myeloid Leukemia in the Developing World: Barriers and Solutions
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Medicine by Alexandros G. Sfakianakis

09:25

BATF3 promotes malignant phenotype of colorectal cancer through the S1PR1/p-STAT3/miR-155-3p/WDR82 axis
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Medicine by Alexandros G. Sfakianakis

09:25

ERK3/MAPK6 is required for KRAS-mediated NSCLC tumorigenesis
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Medicine by Alexandros G. Sfakianakis

09:24

Serum level of interleukin‐35 as a potential prognostic factor for gastric cancer
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Medicine by Alexandros G. Sfakianakis

09:24

Changes in DNA methylation after 6‐week exercise training in colorectal cancer survivors: A preliminary study
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Medicine by Alexandros G. Sfakianakis

09:24

Carboplatin and hypomagnesemia: Is it really a problem?
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Medicine by Alexandros G. Sfakianakis

09:23

USP21 upregulation in cholangiocarcinoma promotes cell proliferation and migration in a deubiquitinase‐dependent manner
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Medicine by Alexandros G. Sfakianakis

09:23

Radium‐223 in Asian patients with castration‐resistant prostate cancer with symptomatic bone metastases: A single‐arm phase 3 study
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Medicine by Alexandros G. Sfakianakis

09:23

Distribution of tumor subtypes in bilateral breast cancer: Comparison between synchronous and metachronous cancer
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Medicine by Alexandros G. Sfakianakis

09:23

Definitive radiotherapy consisting of whole pelvic radiotherapy with no central shielding and CT-based intracavitary brachytherapy for cervical cancer: feasibility, toxicity, and oncologic outcomes in Japanese patients
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Medicine by Alexandros G. Sfakianakis

09:22

Organoid culture system for patient-derived lung metastatic osteosarcoma
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Medicine by Alexandros G. Sfakianakis

09:22

Development and validation of a fourteen- innate immunity-related gene pairs signature for predicting prognosis head and neck squamous cell carcinoma
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Medicine by Alexandros G. Sfakianakis

09:21

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Established fibrous peritoneal metastasis in an immunocompetent mouse model similar to clinical immune microenvironment of gastric cancer
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Medicine by Alexandros G. Sfakianakis

09:21

Prostate cancer tumour control probability modelling for external beam radiotherapy based on multi-parametric MRI-GTV definition
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Medicine by Alexandros G. Sfakianakis

09:21

An immunochemistry-based screen for chemical inhibitors of DNA-protein interactions and its application to human CGGBP1
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Medicine by Alexandros G. Sfakianakis

09:20

Prognostic performance of qSOFA in oncology patients admitted to the emergency department with suspected infection
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Medicine by Alexandros G. Sfakianakis

09:20

Who are the optimal candidates for partial breast irradiation?
…

Medicine by Alexandros G. Sfakianakis

09:20

LINC01133 promotes the progression of cervical cancer via regulating miR‐30a‐5p/FOXD1
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Medicine by Alexandros G. Sfakianakis

09:18

Clinical characterization of glioblastoma patients living longer than 2 years: A retrospective analysis of two Italian institutions
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Medicine by Alexandros G. Sfakianakis

09:18

Novel 5‐point 18‐FDG‐PET/CT visual scoring system for assessing treatment response in patients with oesophageal or gastro‐oesophageal junction carcinoma
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Medicine by Alexandros G. Sfakianakis

09:18

Cytoreductive surgery and HIPEC in colorectal cancer—did we get hold of the wrong end of the stick?
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Medicine by Alexandros G. Sfakianakis

09:17

Confounding factors of transvaginal ultrasound accuracy in endometrial cancer.
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Medicine by Alexandros G. Sfakianakis

09:17

The expression of p16 and galectin-3 in cervical intraepithelial neoplasia (CIN) and squamous cell carcinoma (SCC) uterine cervix.
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Medicine by Alexandros G. Sfakianakis

09:17

The effect of maternal vitamin D levels on placental shear wave elastography findings in the first trimester.
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Medicine by Alexandros G. Sfakianakis

09:17

Selection of patients with esophageal varices for liver resection of hepatocellular carcinoma.
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Medicine by Alexandros G. Sfakianakis

09:17

Cytoreductive surgery and HIPEC in colorectal cancer—did we get hold of the wrong end of the stick?
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Medicine by Alexandros G. Sfakianakis

09:16

Left Ventricular Geometrical Changes in Severely Obese Adolescents: Prevalence, Determinants, and Clinical Implications
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Medicine by Alexandros G. Sfakianakis

08:49

Intracranial capillary hemangiomas: literature review in pediatric and adult population
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Medicine by Alexandros G. Sfakianakis

08:48

Enhanced photocatalytic activity of annealed polycarbazole-tinoxide nanocomposite against RhB and MB dyes under UV and natural sunlight irradiations
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Medicine by Alexandros G. Sfakianakis

08:48

Evaluating the Impact of Calcification on Plaque Vulnerability from the Aspect of Mechanical Interaction Between Blood Flow and Artery Based on MRI
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Medicine by Alexandros G. Sfakianakis

08:48

High-throughput isolation of fetal nucleated red blood cells by multifunctional microsphere-assisted inertial microfluidics
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Medicine by Alexandros G. Sfakianakis

08:48

Task-Specific Tremor Quantification in a Clinical Setting for Parkinson’s Disease
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Medicine by Alexandros G. Sfakianakis

08:47

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Intrathoracic use of a small ultrasonic probe for localizing small lung tumors in thoracoscopic surgery: Empirical results and comparison with preoperative CT images
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Medicine by Alexandros G. Sfakianakis

08:47

Radiological and clinical differences between robotic-assisted pedicle screw fixation with and without real-time optical tracking
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Medicine by Alexandros G. Sfakianakis

08:46

Asylum-Seeking Children with Medical Complexity and Rare Diseases in a Tertiary Hospital in Switzerland
…

Medicine by Alexandros G. Sfakianakis

08:46

A comprehensive review of the great auricular nerve graft
…

Medicine by Alexandros G. Sfakianakis

08:46

Contemporary Management of Hepatic Cyst Disease: Techniques and Outcomes at a Tertiary Hepatobiliary Center
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Medicine by Alexandros G. Sfakianakis

08:45

Toll-like Receptor 4 Inhibitor TAK-242 Improves Fulminant Hepatitis by Regulating Accumulation of Myeloid-Derived Suppressor Cell
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Medicine by Alexandros G. Sfakianakis

08:45

Homozygous deletion of CDKN2A by fluorescence in situ hybridization is prognostic in grade 4, but not grade 2 or 3, IDH-mutant astrocytomas
…

Medicine by Alexandros G. Sfakianakis

08:45

Independent contributions of the face, body, and gait to the representation of the whole person
…

Medicine by Alexandros G. Sfakianakis

08:44

Oxygen saturation during sleep as a predictor of inflammation in anovulatory women
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Medicine by Alexandros G. Sfakianakis

08:44

The role of Weber’s law in human time perception
…

Medicine by Alexandros G. Sfakianakis

08:44

Go-sha-jinki-Gan Alleviates Inflammation in Neurological Disorders via p38-TNF Signaling in the Central Nervous System
…

Medicine by Alexandros G. Sfakianakis

08:43

3D Echocardiography Provides Highly Accurate 3D Printed Models in Congenital Heart Disease
…

Medicine by Alexandros G. Sfakianakis

08:43

Rheumatology and Postural Tachycardia Syndrome
…

Medicine by Alexandros G. Sfakianakis

08:41

Risk factors for medullary infarction after endovascular trapping of vertebral artery dissecting aneurysms
…

Medicine by Alexandros G. Sfakianakis

08:41

Circulating levels of cytokines are increased in restless legs syndrome
…

Medicine by Alexandros G. Sfakianakis

08:41

Antimicrobial photodynamic therapy against Propionibacterium acnes biofilms using hypericin ( Hypericum perforatum ) photosensitizer: in vitro study
…

Medicine by Alexandros G. Sfakianakis

08:41

Retroperitoneal Mass—Castleman Disease
…

Medicine by Alexandros G. Sfakianakis

08:40

Mitomycin C plus cisplatin for systemic treatment of recurrent BRCA1 -associated ovarian cancer
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Medicine by Alexandros G. Sfakianakis

08:39

Glioma progression is suppressed by Naringenin and APO2L combination therapy via the activation of apoptosis in vitro and in vivo
…

Medicine by Alexandros G. Sfakianakis

08:39

A novel germline variant in RET gene resulting in an additional cysteine in a family with familial medullary thyroid carcinoma
…

Medicine by Alexandros G. Sfakianakis

08:39

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Ubiquitin-specific protease 7 is a druggable target that is essential for pancreatic cancer growth and chemoresistance
…

Medicine by Alexandros G. Sfakianakis

08:39

A phase 1 study of PF-06840003, an oral indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor in patients with recurrent malignant glioma
…

Medicine by Alexandros G. Sfakianakis

08:38

ABCG2 C421A polymorphisms affect exposure of the epidermal growth factor receptor inhibitor gefitinib
…

Medicine by Alexandros G. Sfakianakis

08:38

Translational approach from preclinical to clinical: comparison of dose finding methods of a new Bcl2 inhibitor using PK-PD modeling and interspecies extrapolation
…

Medicine by Alexandros G. Sfakianakis

08:38

Drain versus no drain after hip hemi-arthroplasty for femoral neck fractures; differences in clinical outcomes
…

Medicine by Alexandros G. Sfakianakis

08:37

Real-world assessment of afatinib for patients with EGFR -positive non-small cell lung cancer
…

Medicine by Alexandros G. Sfakianakis

08:36

Ubiquitin-specific protease 7 is a druggable target that is essential for pancreatic cancer growth and chemoresistance
…

Medicine by Alexandros G. Sfakianakis

08:36

A phase 1 study of PF-06840003, an oral indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor in patients with recurrent malignant glioma
…

Medicine by Alexandros G. Sfakianakis

08:36

ABCG2 C421A polymorphisms affect exposure of the epidermal growth factor receptor inhibitor gefitinib
…

Medicine by Alexandros G. Sfakianakis

08:36

Persistent primitive olfactory artery without a hairpin turn.
…

Medicine by Alexandros G. Sfakianakis

08:30

Eosinophilic Angiocentric Fibrosis Invading the Nasal Septum: A Case Report and Review of Literature.
…

Medicine by Alexandros G. Sfakianakis

08:29

Subtotal Petrosectomy With Preservation of Chorda Tympani for Petrous Bone Cholesteatoma: Case Report.
…

Medicine by Alexandros G. Sfakianakis

08:29

Endoscopic prelacrimal approach to lateral recess of sphenoid sinus: feasibility study.
…

Medicine by Alexandros G. Sfakianakis

08:29

Spontaneous Intracranial Hypotension.
…

Medicine by Alexandros G. Sfakianakis

08:28

Complications Associated with Lumbar Drain Placement for Endovascular Aortic Repair.
…

Medicine by Alexandros G. Sfakianakis

08:27

Ethmoid Sinus Mucosal and Lacrimal Sac Flap Anastomosing in Patients With Failed Dacryocystorhinostomy.
…

Medicine by Alexandros G. Sfakianakis

08:27

Association of human papillomavirus integration with better patient outcomes in oropharyngeal squamous cell carcinoma
…

Medicine by Alexandros G. Sfakianakis

08:26

Outcomes of Venous End‐to‐Side Microvascular Anastomoses of the Head and Neck
…

Medicine by Alexandros G. Sfakianakis

08:25

Audiovestibular neuropathy in an immunocompetent man with cryptococcal meningitis
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Medicine by Alexandros G. Sfakianakis

08:25

The role of nasal congestion as a defence against respiratory viruses
…

Medicine by Alexandros G. Sfakianakis

08:24

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Longitudinal economic analysis of Bonebridge 601 versus percutaneous bone anchored hearing devices over a 5‐year follow‐up period
…

Medicine by Alexandros G. Sfakianakis

08:24

Composite submental flaps in facial reconstructive surgery involving the zygoma and orbit
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Medicine by Alexandros G. Sfakianakis

08:23

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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia,

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Medicine by Alexandros G. Sfakianakis

Medicine by Sfakianakis G. Alexandros

Third Cranial Nerve Palsy Presenting with Unilateral Diplopia and Strabismus in a 24-Year-Old Woman with COVID-19.
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Medicine by Sfakianakis G. Alexandros

08:21

Torsades de Pointes During Myringotomy in a Child with Congenital Long QT Syndrome: A Case Report.
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Medicine by Sfakianakis G. Alexandros

08:21

An Uncommon Lung Neoplasm in a Young Patient: Diagnostic Challenges.
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Medicine by Sfakianakis G. Alexandros

08:21

Spontaneous Biloma Resulting from Intrahepatic Bile Duct Perforation Coexisting with Intrahepatic Cholelithiasis and Cholangiocarcinoma: A Case Report and Literature Review.
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Medicine by Sfakianakis G. Alexandros

08:21

Rare Human Epidermal Growth Factor Receptor 2 (HER-2)-Positive Neuroendocrine Carcinoma of the Breast: A Case Report with 9-Year Follow-up.
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Medicine by Sfakianakis G. Alexandros

08:20

A Case of Critical Lower-Limb Ischemia in a 29-Year-Old Man with Autoimmune Polyglandular Syndrome Type 1 (APS-1).
…

Medicine by Sfakianakis G. Alexandros

08:20

Paratesticular Dermoid Cyst Mimicking a Torsed Supernumerary Testis: A Case Report.
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Medicine by Sfakianakis G. Alexandros

08:20

Cyclin E overexpression confers resistance to trastuzumab through noncanonical phosphorylation of SMAD3 in HER2+ breast cancer.
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Medicine by Sfakianakis G. Alexandros

08:20

Metallophosphoesterase 1, a novel candidate gene in hepatocellular carcinoma malignancy and recurrence.
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Medicine by Sfakianakis G. Alexandros

08:19

FGF13 interaction with SHCBP1 activates AKT-GSK3α/β signaling and promotes the proliferation of A549 cells.
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Medicine by Sfakianakis G. Alexandros

08:19

The role of TP53 pathogenic variants in early-onset HER2-positive breast cancer.
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Medicine by Sfakianakis G. Alexandros

08:19

Predictive value of tumor-infiltrating lymphocytes for pathological response to neoadjuvant chemotherapy in breast cancer patients with axillary lymph node metastasis.
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Medicine by Sfakianakis G. Alexandros

08:19

FDA Approval Summary: Tucatinib for the Treatment of Patients with Advanced or Metastatic HER2-Positive Breast Cancer.
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Medicine by Sfakianakis G. Alexandros

08:18

Analysis of the serial circulating tumor cell count during neoadjuvant chemotherapy in breast cancer patients.
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Medicine by Sfakianakis G. Alexandros

08:17

Durable clinical benefit from pyrotinib combined with carboplatin in HER2-positive relapsed breast cancer previously treated with taxanes, anthracyclines, and trastuzumab.
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Medicine by Sfakianakis G. Alexandros

08:17

Exosomal miR-1246 and miR-155 as predictive and prognostic biomarkers for trastuzumab-based therapy resistance in HER2-positive breast cancer.
…

Medicine by Sfakianakis G. Alexandros

08:17

Can we avoid axillary lymph node dissection in N2 breast cancer patients with chemo-sensitive tumours such as HER2 and TNBC?
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Medicine by Sfakianakis G. Alexandros

08:17

The histone H2B ubiquitin ligase RNF40 is required for HER2-driven mammary tumorigenesis.
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Medicine by Sfakianakis G. Alexandros

08:16

Sensitivity and Specificity of Bedside Screening Tests for Detection of Aspiration in Patients Admitted to a Public Rehabilitation Hospital.
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Medicine by Sfakianakis G. Alexandros

08:16

Effects of Physical Rehabilitation and Nutritional Intake Management on Improvement in Tongue Strength in Sarcopenic Patients.
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Medicine by Sfakianakis G. Alexandros

08:16

Swallowing and Communication Management of Tracheostomy and Laryngectomy in the Context of COVID-19: A Review.
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Medicine by Sfakianakis G. Alexandros

08:16

Electroacupuncture Involved in Motor Cortex and Hypoglossal Neural Control to Improve Voluntary Swallowing of Poststroke Dysphagia Mice.
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Medicine by Sfakianakis G. Alexandros

08:15

Clinical Effects and Safety of Electroacupuncture for the Treatment of Poststroke Dysphagia: A Comprehensive Systematic Review and Meta-Analysis.
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Medicine by Sfakianakis G. Alexandros

08:15

Prosthetic Rehabilitation of a Nasomaxillary Defect Utilizing a two-Component Prosthesis: a Clinical Report.
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Medicine by Sfakianakis G. Alexandros

08:14

Targeting the sensory feedback within the swallowing network-Reversing artificially induced pharyngolaryngeal hypesthesia by central and peripheral stimulation strategies.
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Medicine by Sfakianakis G. Alexandros

08:14

Endoscopic Orbital Decompression: Technical Pearls and Pitfalls of an Evolving Technique.
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Medicine by Sfakianakis G. Alexandros

08:14

Skull Base; +29 new citations
Page 1Select search result to email or save1Morphologie. 2020 Oct 14;S1286-0115(20)30089-8. doi: 10.1016/j.morpho.2020.09.007. Online ahead of print.Study of the growth and shape of the brain and cranial base during the first two years of lifeC Delteil 1, E Lesieur 2, L Tuchtan 3, A Carballeira Alvarez 4, K Chaumoitre 5, B Saliba 6, P Adalian 6, M-D Piercecchi-Marti 3Affiliations expandPMID: 33069567 DOI: 10.1016/j.morpho.2020.09.007AbstractOntogeny of the cranial base and the brain integrates…

Medicine by Sfakianakis G. Alexandros

08:14

Effect of septoplasty on left ventricular myocardial performance in patients with nasal septum deviation.
…

Medicine by Sfakianakis G. Alexandros

08:11

Assessment of otolith function using vestibular evoked myogenic potential in women during pregnancy.
…

Medicine by Sfakianakis G. Alexandros

08:11

Neonatal exposure to an inflammatory cytokine, epidermal growth factor, results in the deficits of mismatch negativity in rats.
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Medicine by Sfakianakis G. Alexandros

08:10

Evaluation of Perioperative Intestinal Motility Using a Newly Developed Real-Time Monitoring System During Surgery.
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Medicine by Sfakianakis G. Alexandros

08:09

Early Induction of Bedside Pneumoperitoneum in the Management of Residual Pleural Space and Air Leaks After Pulmonary Resection.
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Medicine by Sfakianakis G. Alexandros

08:09

The Usefulness of a Preoperative Nomogram for Predicting the Probability of Conversion from Laparoscopic to Open Distal Pancreatectomy: A Single-Center Experience.
…

Medicine by Sfakianakis G. Alexandros

08:08

Delta Neutrophil Index and Neutrophil-to-Lymphocyte Ratio in the Differentiation of Thyroid Malignancy and Nodular Goiter.
…

Medicine by Sfakianakis G. Alexandros

08:08

Redirection of lower eyelid eyelashes by eyelid margin splitting and anterior lamellar repositioning for patients with non-entropion trichiasis.
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Medicine by Sfakianakis G. Alexandros

08:08

Upskilling the surgical workforce for vascular access provision during the COVID-19 pandemic – The Salisbury experience.
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Medicine by Sfakianakis G. Alexandros

08:07

A systematic review of outcomes following hand reconstruction using flaps from the superficial palmar branch of the radial artery (SUPBRA) system.
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Medicine by Sfakianakis G. Alexandros

08:06

The scratch collapse test: A systematic review.
…

Medicine by Sfakianakis G. Alexandros

08:04

Bilateral immediate two-stage breast reconstruction in patients with unilateral breast cancer: Outcomes analysis and risk assessment.
…

Medicine by Sfakianakis G. Alexandros

08:03

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Clinical Outcome and Toxicity in the Treatment of Anaplastic Thyroid Cancer in Elderly Patients.
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Medicine by Sfakianakis G. Alexandros

08:03

Coprevalence of Presbycusis and Its Effect on Outcome of Voice Therapy in Patients With Presbyphonia.
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Medicine by Sfakianakis G. Alexandros

08:03

Axitinib plus avelumab in the treatment of recurrent glioblastoma: a stratified, open-label, single-center phase 2 clinical trial (GliAvAx).
…

Medicine by Sfakianakis G. Alexandros

08:03

Corticosteroid discontinuation, complete clinical response and remission in juvenile dermatomyositis.
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Medicine by Sfakianakis G. Alexandros

08:02

Strain Elastosonography Measurement in Patients with Primary Muscle Tension Dysphonia Compared with Healthy Speakers: A Pilot Study.
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Medicine by Sfakianakis G. Alexandros

08:02

Effects of Different Diets on Microbiota in The Small Intestine Mucus and Weight Regulation in Rats.
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Medicine by Sfakianakis G. Alexandros

08:02

LncRNA SNHG1 promotes cell proliferation in laryngeal cancer via Notch1 signaling pathway.
…

Medicine by Sfakianakis G. Alexandros

08:01

LINC01605 promotes the proliferation of laryngeal squamous cell carcinoma through targeting miR-493-3p.
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Medicine by Sfakianakis G. Alexandros

08:01

Neonatal Mandibular Distraction Osteogenesis in Infants With Pierre Robin Sequence.
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Medicine by Sfakianakis G. Alexandros

08:01

Comparison of the MultiViewScope Stylet Scope and the direct laryngoscope with the Miller blade for the intubation in normal and difficult pediatric airways: A randomized, crossover, manikin study.
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Medicine by Sfakianakis G. Alexandros

08:00

Second Primary Tumors in head and neck cancer patients: the importance of a ‘tailored’ surveillance.
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Medicine by Sfakianakis G. Alexandros

08:00

[Current diagnostic imaging and treatment planning for laryngeal cancer].
…

Medicine by Sfakianakis G. Alexandros

08:00

Identification of Prognosis Associated microRNAs in HNSCC Subtypes Based on TCGA Dataset.
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Medicine by Sfakianakis G. Alexandros

07:59

Outcome of an outpatient specialty clinic for chronic epipharyngitis.
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Medicine by Sfakianakis G. Alexandros

07:59

Augmentation of the posterior pharyngeal wall with autologous tragal cartilage for management of velopharyngeal valve insufficiency in adults.
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Medicine by Sfakianakis G. Alexandros

07:58

Co-treatment with endoscopic laryngopharyngeal surgery and endoscopic submucosal dissection.
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Medicine by Sfakianakis G. Alexandros

07:58

Efficacy of polyglycolic acid sheets and fibrin glue for the prevention of post-ELPS bleeding.
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Medicine by Sfakianakis G. Alexandros

07:57

Vocal Indicators of Size, Shape and Body Composition in Polish Men.
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Medicine by Sfakianakis G. Alexandros

07:57

[125Ⅰ seed brachytherapy for recurrent salivary gland carcinoma after external radiotherapy].
…

Medicine by Sfakianakis G. Alexandros

07:56

A cutoff thyroglobulin value suggestive of distant metastases in differentiated thyroid cancer patients.
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Medicine by Sfakianakis G. Alexandros

07:56

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Radical resection and improvised manubriosternal reconstruction technique for solitary manubriosternal metastasis from papillary thyroid cancer.
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Medicine by Sfakianakis G. Alexandros

07:55

Hypericin, a medicinal compound from St. John’s Wort, inhibits genotoxicity induced by mutagenic agents in V79 cells.
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Medicine by Sfakianakis G. Alexandros

07:55

Hot-processed virgin coconut oil abrogates cisplatin-induced nephrotoxicity by restoring redox balance in rats compared to fermentation-processed virgin coconut oil.
…

Medicine by Sfakianakis G. Alexandros

07:54

In-vivo and in-silico toxicity studies of daidzein: an isoflavone from soy.
…

Medicine by Sfakianakis G. Alexandros

07:54

The beneficial effects of antioxidants combination on cardiac injury induced by tetrachloromethane.
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Medicine by Sfakianakis G. Alexandros

07:53

Recent advances in high-throughput flow cytometry for drug discovery.
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Medicine by Sfakianakis G. Alexandros

07:53

[Subjective significance of olfactory dysfunction after laryngectomy : Let's ask our patients].
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Medicine by Sfakianakis G. Alexandros

07:53

Persistent primitive olfactory artery without a hairpin turn.
…

Medicine by Sfakianakis G. Alexandros

07:52

Dietary fiber, genetic variations of gut microbiota-derived short-chain fatty acids, and bone health in UK biobank.
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Medicine by Sfakianakis G. Alexandros

07:50

Roux-en-Y gastric bypass versus sleeve gastrectomy for remission of type 2 diabetes.
…

Medicine by Sfakianakis G. Alexandros

07:49

Glycemic Control and Variability of Diabetes Secondary to Total Pancreatectomy Assessed by Continuous Glucose Monitoring.
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Medicine by Sfakianakis G. Alexandros

07:49

Metabolomics of lean/overweight insulin resistant females reveals alterations in steroids and fatty acids.
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Medicine by Sfakianakis G. Alexandros

07:49

Treatment of gestational diabetes mellitus and offspring early childhood growth.
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Medicine by Sfakianakis G. Alexandros

07:48

Serum testosterone is inversely, and sex hormone-binding globulin directly, associated with all-cause mortality in men.
…

Medicine by Sfakianakis G. Alexandros

07:48

The PNPLA3-I148M variant confers an antiatherogenic lipid profile in insulin-resistant patients.
…

Medicine by Sfakianakis G. Alexandros

07:48

Chemotherapeutic effects of MEK kinase inhibitor and BRAF kinase inhibitor on KRAS-mutated human colon cancer cell lines with different microsatellite instability.
…

Medicine by Sfakianakis G. Alexandros

07:48

Assessment of SARS-CoV-2 in the Cerumen of COVID-19-Positive Patients.
…

Medicine by Sfakianakis G. Alexandros

07:48

Factors Predictive of Outcome in Inferior Turbinate Surgery.
…

Medicine by Sfakianakis G. Alexandros

07:47

Eosinophilic Angiocentric Fibrosis Invading the Nasal Septum: A Case Report and Review of Literature.
…

Medicine by Sfakianakis G. Alexandros

07:47

Subtotal Petrosectomy With Preservation of Chorda Tympani for Petrous Bone Cholesteatoma: Case Report.
…

Medicine by Sfakianakis G. Alexandros

07:46

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Endoscopic prelacrimal approach to lateral recess of sphenoid sinus: feasibility study.
…

Medicine by Sfakianakis G. Alexandros

07:46

Spontaneous Intracranial Hypotension.
…

Medicine by Sfakianakis G. Alexandros

07:45

Complications Associated with Lumbar Drain Placement for Endovascular Aortic Repair.
…

Medicine by Sfakianakis G. Alexandros

07:45

Ethmoid Sinus Mucosal and Lacrimal Sac Flap Anastomosing in Patients With Failed Dacryocystorhinostomy.
…

Medicine by Sfakianakis G. Alexandros

07:45

Regional anesthesia for scapular fracture surgery: an educational review of anatomy and techniques.
…

Medicine by Sfakianakis G. Alexandros

07:45

Pre-emptive epidural analgesia for acute and chronic post-thoracotomy pain in adults: a systematic review and meta-analysis.
…

Medicine by Sfakianakis G. Alexandros

07:44

lnc‐HOTAIR predicts hepatocellular carcinoma in chronic hepatitis C genotype 4 following direct‐acting antivirals therapy
…

Medicine by Sfakianakis G. Alexandros

07:43

Evaluation of the Electroglottographic Signal Variability in Organic and Functional Dysphonia.
…

Medicine by Sfakianakis G. Alexandros

07:43

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Brain metastases from Truncal and extremity bone and soft tissue sarcoma: Single institution study of oncologic outcomes.
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International journal of pediatric otorhinolaryngology,http://goo.gl/4YdRhzSevere tracheobronchial harm due to lithium button battery aspiration: An in vitro study of the pathomechanism and injury pattern.Severe tracheobronchial harm due to lithium button battery aspiration: An in vitro study of the pathomechanism and injury pattern. Int J Pediatr Otorhinolaryngol. 2020 Oct 08;139:110431 Authors: Voelker J, Voelker C, Engert J, Schendzielorz P, Hagen R, Rak K Abstract BACKGROUND: Button battery…

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Clinical Cancer Research Online First ArticlesNRF2 activation promotes aggressive lung cancer and associates with poor clinical outcomesPurpose: Stabilization of the transcription factor NRF2 through genomic alterations in KEAP1 and NFE2L2 occurs in a quarter of lung adenocarcinoma (LUAD) and a third of lung squamous (LUSC) patients. In LUAD, KEAP1 loss often co-occurs with STK11 loss and KRAS activating alterations. Despite its prevalence, the impact of NRF activation on tumor progression and…

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AntibioticsAntibiotics, Vol. 9, Pages 715: Aureolic Acid Group of Agents as Potential Antituberculosis DrugsAntibiotics, Vol. 9, Pages 715: Aureolic Acid Group of Agents as Potential Antituberculosis Drugs Antibiotics doi: 10.3390/antibiotics9100715 Authors: Julia Bespyatykh Dmitry Bespiatykh Maja Malakhova Ksenia Klimina Andrey Bespyatykh Anna Varizhuk Anna Tevyashova Tatiana Nikolenko Galina Pozmogova Elena Ilina Egor Shitikov Mycobacterium tuberculosis is one of the most dangerous pathogens….

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07:40

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Case reports in endocrinology – hindawiACTH-Independent Cushing’s Syndrome Associated with Left Adrenocortical Oncocytoma of Uncertain Malignant Potential.ACTH-Independent Cushing’s Syndrome Associated with Left Adrenocortical Oncocytoma of Uncertain Malignant Potential. Case Rep Endocrinol. 2020;2020:8816527 Authors: Sica GS, Siragusa L, Sensi B, Bellato V, Floris P, Rovella V, Mauriello A, Di Prete M, Telesca R, Ciavoni V, Cardillo C, Di Daniele N, Tesauro M Abstract Adrenocortical oncocytomas…

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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia,

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Medicine by Alexandros G. Sfakianakis

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Improving aseptic injection standards in aesthetic clinical practice
Improving aseptic injection standards in aesthetic clinical practice: AbstractIntroductionThe rise in popularity and demand for non‐surgical injectable aesthetic procedures is inherently accompanied by an increase in reported complications, particularly those related to infection. Aseptic technique is under the control of aesthetic practitioners and can be modified to minimise the potential for cross‐contamination and infection. This should be a key consideration during all clinical procedures, particularly…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:43

Laser Tattoo Removal: Fundamental Principles and Practical Approach
Laser Tattoo Removal: Fundamental Principles and Practical Approach: ABSTRACTTattoos have long become a part of human civilization. However, as the number of people who get tattoos increases, so is the number of people who wish to have their tattoos removed. Compared to other methods, laser‐based devices are associated with the best efficacy and least side effects in tattoo removal. Lack of understanding of the fundamental principles of laser and managing its parameters may result in suboptimal result…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:37

Use of biologic therapies for psoriasis during pregnancy
Use of biologic therapies for psoriasis during pregnancy and long‐term outcomes of exposed children: A 14‐year real‐life experience at a tertiary center in Turkey and review of the literature: ABSTRACTData regarding the use of biologic therapies for psoriasis during pregnancy are scarce with even more limited knowledge about the long‐term safety of in utero exposure. We retrospectively evaluated nine pregnancies in six women with psoriasis who were exposed to biologic therapies between 2006 and 2019…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:37

Serum S100A12 levels: possible association with skin sclerosis and interstitial lung disease in systemic sclerosis
Serum S100A12 levels: possible association with skin sclerosis and interstitial lung disease in systemic sclerosis: AbstractDamage‐associated molecular patterns (DAMPs) have drawn much attention as a member of disease‐associated molecules in systemic sclerosis (SSc). In this study we investigated the potential contribution of S100A12, a member of DAMPs, to the development of SSc by evaluating S100A12 expression in the lesional skin and the clinical correlation of serum S100A12 levels. S100A12 expression…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:37

Early transcriptional changes after UVB treatment in atopic dermatitis includes inverse regulation of IL‐36γ and IL‐37
Early transcriptional changes after UVB treatment in atopic dermatitis includes inverse regulation of IL‐36γ and IL‐37: AbstractBackgroundPhototherapy with narrow‐band Ultraviolet B (nb‐UVB) is a major therapeutic option in atopic dermatitis (AD), yet knowledge of the early molecular responses to this treatment is lacking.ObjectiveTo map the early transcriptional changes in AD skin in response to nb‐UVB treatment.MethodsAdult patients (n = 16) with AD were included in the study and scored with validated…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:36

Effects of perioperative oral care on postoperative inflammation following heart valve surgery
Effects of perioperative oral care on postoperative inflammation following heart valve surgery: AbstractObjectiveWhether oral health care during the perioperative period can lead to a better outcome after heart valve surgery has not been adequately elucidated. We examined the effects of perioperative oral care on postoperative inflammation response in patients who underwent heart valve surgery.Materials and MethodsIn this retrospective cohort study, 223 patients scheduled for single valve heart surgery…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:36

Cerebrospinal Fluid Spread in a Child with Pleomorphic Xanthoastrocytoma
Cerebrospinal Fluid Spread in a Child with Pleomorphic Xanthoastrocytoma: A Report with Cytopathological Evidence: Publication date: Available online 17 October 2020Source: World NeurosurgeryAuthor(s): Madhivanan Karthigeyan, Pankaj Kumar, Pravin Salunke, Manish Rohilla, Debjyoti Chatterjee, Chirag Kamal AhujaAbstractBackgroundPleomorphic xanthoastrocytoma (PXA), a relatively uncommon, World Health Organization grade II tumor of astrocytic origin, occurs in children and in general carries good prognosis….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:35

Sellar Cholesterol Granuloma Mimicking Cystic Sellar Lesions
Sellar Cholesterol Granuloma Mimicking Cystic Sellar Lesions: A Report of Three Cases and Literature Review: Publication date: December 2020Source: World Neurosurgery, Volume 144Author(s): Martin Pilonieta, Monica Martin, Juan M. Revuelta Barbero, Douglas A. Hardesty, Ricardo L. Carrau, Bradley A. Otto, Jose Otero, Luma Ghalib, Daniel M. Prevedello

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:31

Validation of the UICC 8th edition staging of oral cavity squamous cell carcinoma
Validation of the UICC 8th edition staging of oral cavity squamous cell carcinoma in a UK cohort: The eighth edition of the Union for International Cancer Control (UICC) staging manual was recently introduced. The staging of oral cavity squamous cell carcinoma saw changes in relation to depth of invasion and extra-nodal extension. We aimed to evaluate this system and its prognostic ability in a UK cohort. A retrospective review was undertaken of patients diagnosed with squamous cell carcinoma (SCC)…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:30

Anatomy of the respiratory system in the, “Portrait of a Musician” by Leonardo da Vinci
Anatomy of the respiratory system in the, “Portrait of a Musician” by Leonardo da Vinci: The object of the research is the painting, Portrait of a Musician’’. Upon closer examination of the painting, we discovered three details. Two have the shape of trachea and bronchi and the third a larynx. By moving the details through the program Paint X we got an image of the larynx, trachea and bronchi. The larynx is presented by thyroid and cricoid cartilage. The characteristic cartilaginous rings are distinguished…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:29

A non-invasive ultrasound imaging method to measure acute radiation-induced bladder wall thickening in rats
A non-invasive ultrasound imaging method to measure acute radiation-induced bladder wall thickening in rats: Methods for the non-invasive quantification of changes in bladder wall thickness as potential predictors of radiation cystitis in pre-clinical research would be desirable. The use of ultrasound for this aim se…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:28

Evaluation of OAR dose sparing and plan robustness of beam-specific PTV in lung cancer IMRT treatment
Evaluation of OAR dose sparing and plan robustness of beam-specific PTV in lung cancer IMRT treatment: Margins are employed in radiotherapy treatment planning to mitigate the dosimetric effects of geometric uncertainties for the clinical target volume (CTV). Here, we proposed a margin concept that takes into co…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:28

The association between micronutrient status and sleep quality in patients with depression: a case-control study
The association between micronutrient status and sleep quality in patients with depression: a case-control study: AbstractPurposeFew previous studies estimated the association between micronutrient status and sleep quality; no previous work was done in patients with depression compared with healthy controls. MethodsUsing a case-control design, 96 patients with depression were age- and sex-matched with 96 healthy controls. Dietary assessment utilized a standardized questionnaire,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:27

Ipsilateral radiation for squamous cell carcinoma of the tonsil
Ipsilateral radiation for squamous cell carcinoma of the tonsil: American Radium Society appropriate use criteria executive summary: AbstractBackgroundWe conducted the current systemic review to provide up‐to‐date literature summary and optimal evidence‐based recommendations for ipsilateral radiation for squamous cell carcinoma of the tonsil.MethodsWe performed literature search of peer‐reviewed journals through PubMed. The search strategy and subject‐specific keywords were developed based on the…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:27

Leiomyosarcoma in a cervical myelomeningocele
Leiomyosarcoma in a cervical myelomeningocele: a rare complication in a neglected case: AbstractBackground and importanceAsymptomatic myelomeningoceles are usually more of cosmetic deformities and left without evaluation and untreated, amongst low socio-economic strata. Such midline swellings, if left neglected may become the seat for malignancies, usually of squamous cell origin. Clinical presentationThe authors report a case of an 18-year-old male patient who developed leiomyosarcoma…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:26

Recombinant human endostatin plus paclitaxel/nedaplatin for recurrent or metastatic advanced esophageal squamous cell carcinoma: a prospective, single-arm, open-label, phase II study
Recombinant human endostatin plus paclitaxel/nedaplatin for recurrent or metastatic advanced esophageal squamous cell carcinoma: a prospective, single-arm, open-label, phase II study: SummaryBackground The prognosis of esophageal squamous cell carcinoma (ESCC) are still poor. Nedaplatin/paclitaxel regimen has shown activity with lower toxicity in metastatic ESCC. Recombinant human endostatin (Rh-endostatin), an inhibitor of angiogenesis, has shown inhibitory effects on ESCC xenograft. We assessed…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:26

An ovarian torsion in a 2-year-old girl:
An ovarian torsion in a 2-year-old girl: a case report: Abdominal pain is one of the most common complaints by patients in the emergency department. Diarrhea, constipation, and urinary tract infection are the commonest etiologies among these patients, but there are…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:25

Perivascular epithelioid cell tumor (PEComa) of the kidney
Perivascular epithelioid cell tumor (PEComa) of the kidney: an overview of its management and outcomes: Journal of International Medical Research, Volume 48, Issue 10, October 2020. Perivascular epithelioid cell tumor (PEComa) is a rare mesenchymal tumor with unique histological and immunohistochemical characteristics. Malignant renal cell carcinoma is even rarer and its biological behavior is still not clear. We report here a case of malignant PEComa in a male patient. The first symptom of the patient…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:23

Short-lasting unilateral neuralgiform headache with conjunctival injection and tearing with progression to neuromyelitis optica spectrum disorder
A rare case of short-lasting unilateral neuralgiform headache with conjunctival injection and tearing with progression to neuromyelitis optica spectrum disorder: Journal of International Medical Research, Volume 48, Issue 10, October 2020. Short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT) is a rare primary headache syndrome. However, some cases of secondary SUNCT are attributed to underlying diseases such as demyelination. We herein report a case of SUNCT…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:22

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
Brain SciencesBrain Sciences, Vol. 10, Pages 753: Understanding Novel Metaphors: A Milestone in the Developmental Trajectory of Children with Agenesis of the Corpus Callosum?Brain Sciences, Vol. 10, Pages 753: Understanding Novel Metaphors: A Milestone in the Developmental Trajectory of Children with Agenesis of the Corpus Callosum? Brain Sciences doi: 10.3390/brainsci10100753 Authors: Sergio Melogno Maria Antonietta Pinto Chiara Pollice Fausto Badolato Guido Trasimeni Pasquale Parisi This study…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:22

Oncogenic KRAS–expressing organoids with biliary epithelial stem cell properties give rise to biliary tract cancer in mice
Oncogenic KRAS–expressing organoids with biliary epithelial stem cell properties give rise to biliary tract cancer in mice: AbstractBiliary tract cancer (BTC) arises from biliary epithelial cells (BECs) and includes intrahepatic cholangiocarcinoma (IHCC), gallbladder cancer (GC), and extrahepatic cholangiocarcinoma (EHCC). Although frequent KRAS mutations and epigenetic changes at the INK4A/ARF locus have been identified, the molecular pathogenesis of BTC is unclear and the development of corresponding…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:16

Allergenicity at component level of subpollens particles from different sources obtained by osmolar shock: a molecular approach to thunderstorm‐related asthma outbreaks
Allergenicity at component level of subpollens particles from different sources obtained by osmolar shock: a molecular approach to thunderstorm‐related asthma outbreaks: AbstractBackgroundThe so‐called “thunderstorm asthma” (TA) is an uncommon but dramatic outbreak of asthma attacks occurring during a thunderstorm in the pollen and molds season. Mechanisms which make the pollen able to enter the deeper airways and provoke severe asthma symptoms are still unclear.ObjectiveTo test the hypothesis that…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:16

Advances and novel developments in mechanisms of allergic inflammation
Advances and novel developments in mechanisms of allergic inflammation: AbstractIn the past decade, research in the molecular and cellular underpinnings of basic and clinical immunology has significantly advanced our understanding of allergic disorders, allowing scientists and clinicians to diagnose and treat disorders such as asthma, allergic and nonallergic rhinitis, and food allergy. In this review, we discuss several significant recent developments in basic and clinical research as well as important…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:15

Functional properties of single motor units in the human medial pterygoid muscle: task relations and thresholds
Functional properties of single motor units in the human medial pterygoid muscle: task relations and thresholds: AbstractBackgroundLittle is known regarding the functional properties of single motor units (SMUs) in the medial pterygoid muscle (MPt) during jaw movements.ObjectivesThe aims are a) to report the thresholds of onset of MPt SMUs during 4 goal‐directed jaw movement tasks, and b) to determine whether the threshold of onset of SMU activation varies with the velocity of jaw movement and the…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:14

The prevalence of awake bruxism and sleep bruxism in the Dutch adolescent population
The prevalence of awake bruxism and sleep bruxism in the Dutch adolescent population: AbstractObjectivesThis study aimed to assess the prevalence of awake bruxism and sleep bruxism in the Dutch adolescent population. Materials and MethodsAs part of a large epidemiologic survey on oral health of the general Dutch adolescent population in 2017, a total of 920 subjects were asked about their bruxism behavior during daytime and during sleep. The collected data were subjected to stratified analysis by…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:14

Molecular Signature of Extracellular Matrix Pathology in Schizophrenia
Molecular Signature of Extracellular Matrix Pathology in Schizophrenia: AbstractGrowing evidence points to a critical involvement of the extracellular matrix (ECM) in the pathophysiology of schizophrenia (SZ). Decreases of perineuronal nets and altered expression of chondroitin sulphate proteoglycans in glial cells have been identified in several brain regions. GWAS data have identified several SZ vulnerability variants of genes encoding for ECM molecules. Given the potential relevance of ECM functions…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:14

Novel loss‐of‐function variants in DNAH17 cause multiple morphological abnormalities of the sperm flagella in humans and mice
Novel loss‐of‐function variants in DNAH17 cause multiple morphological abnormalities of the sperm flagella in humans and mice: AbstractMultiple morphological abnormalities of the flagella (MMAF) is a genetically heterogeneous disorder leading to male infertility. Recent studies have revealed that DNAH17 variants are associated with MAMF, yet there is no functional evidence in support of their pathnogenicity. Here, we recruited two consanguineous families of Pakistani and Chinese origins, respectively,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:13

“Double-Flash”: An Innovative Method to Diagnose Papillary Thyroid Microcarcinomas
“Double-Flash”: An Innovative Method to Diagnose Papillary Thyroid Microcarcinomas: Publication date: Available online 17 October 2020Source: Ultrasound in Medicine & BiologyAuthor(s): Tiantong Zhu, Jingwen Shi, Bo Wang, Yue Yu, Ying Huang

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:12

Comparison of KD‐SR‐01 robotic partial nephrectomy and 3D‐laparoscopic partial nephrectomy from an operative and ergonomic perspective: a prospective randomized controlled study in porcine models
Comparison of KD‐SR‐01 robotic partial nephrectomy and 3D‐laparoscopic partial nephrectomy from an operative and ergonomic perspective: a prospective randomized controlled study in porcine models: AbstractBackgroundTo investigate the feasibility, validity and security of a new robot platform called KD‐SR‐01 and compare relative merits of KD‐SR‐01 robotic partial nephrectomy (KD‐RPN) and 3D‐Laparoscopic Partial Nephrectomy (3D‐LPN).MethodsTwelve porcine models were randomly and equally divided for…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:11

CTNNB1 p.L31P mutation in an ovarian endometrioid carcinoma with synchronous uterine endometrioid carcinoma
CTNNB1 p.L31P mutation in an ovarian endometrioid carcinoma with synchronous uterine endometrioid carcinoma: Publication date: Available online 18 October 2020Source: Pathology – Research and PracticeAuthor(s): Irene Pecorella, Anna Coppa, Arianna Nicolussi, Lucia Manganaro, Francesco Fiorentin, Innocenza Palaia, Ludovico MuziiAbstractWe performed next generation sequencing of DNA extracted from the neoplastic tissues obtained from a patient who underwent surgery for a large right ovarian carcinoma…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:10

High-risk factors for lymph node metastasis in contralateral central compartment in unilateral papillary thyroid carcinoma（cT1N0）
High-risk factors for lymph node metastasis in contralateral central compartment in unilateral papillary thyroid carcinoma（cT1N0）: Publication date: Available online 18 October 2020Source: European Journal of Surgical OncologyAuthor(s): Bin Zhou, Jianwu QinAbstractObjectiveThe incidence of papillary thyroid carcinoma (PTC) increases yearly. Central lymph node metastasis (CLNM) is common in PTC. Many studies have addressed ipsilateral CLNM; however, few studies have evaluated contralateral CLNM. The…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:09

Hearing and Speech Processing in Midlife
Hearing and Speech Processing in Midlife: Publication date: Available online 17 October 2020Source: Hearing ResearchAuthor(s): Karen S. Helfer, Alexandra JesseHighlights•Changes to subjective and objective hearing are common among middle-aged adults.•Elevated pure-tone thresholds can explain only a portion of objective problems.•Audiovisual speech processing remains intact with aging.•Middle-aged adults exert more effort in speech understanding than younger adults.•Research on middle-aged adults…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:08

Microsurgical Treatment of a Complex Cognard V Tentorial Dural Fistula with Superior Cerebellar Artery Supply
Microsurgical Treatment of a Complex Cognard V Tentorial Dural Fistula with Superior Cerebellar Artery Supply: Publication date: Available online 17 October 2020Source: World NeurosurgeryAuthor(s): Ryan Dimentberg, Svetlana Kvint, Peter Madsen, Gregory Glauser, Omar ChoudhriAbstractThis case video demonstrates a microsurgical technique for the clipping and obliteration of a Cognard V tentorial dural fistula. The patient was a 49-year-old male who presented with progressive upper and lower extremity…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:08

Hypothalamic Cavernomas: Pediatric
Hypothalamic Cavernomas: Pediatric Case Report with 8.5 Year Follow-up and Review of the Literature: Publication date: Available online 17 October 2020Source: World NeurosurgeryAuthor(s): Gennadiy A. Katsevman, Bayan Razzaq, Cesar A. SerranoABSTRACTCavernous malformations (cavernomas) are angiographically occult vascular lesions that can present symptomatically or be discovered incidentally. Rarely, they present in the hypothalamus or in children. We describe the case of a 14-year-old male who presented…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:07

Comparative analysis of the Pipeline and the Derivo flowdiverters for the treatment of unruptured intracranial aneurysms – a multicentric study
Comparative analysis of the Pipeline and the Derivo flowdiverters for the treatment of unruptured intracranial aneurysms – a multicentric study: Publication date: Available online 17 October 2020Source: World NeurosurgeryAuthor(s): Charlotte Zaeske, Lukas Goertz, Franziska Dorn, Bernd Turowski, Nuran Abdullayev, Marc Schlamann, Thomas Liebig, Christoph Kabbasch

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:06

Multifaceted targeting of cationic liposomes via co-delivery of anti-IL-17 siRNA and corticosteroid for topical treatment of psoriasis
Multifaceted targeting of cationic liposomes via co-delivery of anti-IL-17 siRNA and corticosteroid for topical treatment of psoriasis: Publication date: December 2020Source: Medical Hypotheses, Volume 145Author(s): Krishna Yadav, Deependra Singh, Manju Rawat Singh, Madhulika Pradhan

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:05

WNT/β-catenin signaling in the development of liver cancers
WNT/β-catenin signaling in the development of liver cancers: Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Shuai He, Shilei Tang

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:05

The role of glycogen synthase kinase 3 beta in multiple sclerosis
The role of glycogen synthase kinase 3 beta in multiple sclerosis: Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Tayebeh Noori, Ahmad Reza Dehpour, Antoni Sureda, Sajad Fakhri, Eduardo Sobarzo-Sanchez, Mohammad Hosein Farzaei, Esra Küpeli Akkol, Zahra Khodarahmi, Seyede Zahra Hosseini, Seyede Darya Alavi, Samira Shirooie

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:04

Mild asymptomatic primary hyperparathyroidism ……Efficacy of parathyroidectomy compared with active surveillance
Efficacy of parathyroidectomy compared with active surveillance in patients with mild asymptomatic primary hyperparathyroidism: a systematic review and meta-analysis of randomized-controlled studies: AbstractObjectiveParathyroidectomy (PTx) has an established benefit in patients with symptomatic primary hyperparathyroidism (PHPT). However, its efficacy in mild asymptomatic PHPT has not been proven. This study aimed to systematically review and meta-analyze the best available evidence from randomized-controlled…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:03

Αφαίρεση διαφημίσεων


SARS-CoV-2 Detection on Bronchoalveolar Lavage
SARS-CoV-2 Detection on Bronchoalveolar Lavage: An Italian Multicenter experience: Background: Bronchoscopy with bronchoalveolar lavage (BAL) during the SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) pandemic should be reserved to a limited number of clinical indications. The yield of BAL for the diagnosis of suspected or confirmed pulmonary SARS-CoV-2 infection is still unknown. Objectives: We aimed to evaluate the diagnostic ratio of BAL in detecting SARS-CoV-2 pulmonary infection…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:03

The anti-cancer effect of flaxseed lignan derivatives on different acute myeloid leukemia cancer cells
Highlights•ENL has more prominent anti-leukemic effects than other flaxseeds lignans.•ENL promotes selective anti-proliferative and pro-apoptotic effects on AML cells.•The intrinsic apoptotic pathway is activated upon Enterolactone exposure.•This study offers new insights into the health benefits of flaxseeds.AbstractFlaxseeds have been known for their anti-cancerous effects due to the high abundance of lignans released upon ingestion. The most abundant lignan, secoisolariciresinol diglucoside (SDG),…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:00

A synergistic effect of Ambroxol and Beta-Glucosylceramide in alleviating immune-mediated hepatitis: A novel immunomodulatory non-immunosuppressive formulation for treatment of immune-mediated disorders
A synergistic effect of Ambroxol and Beta-Glucosylceramide in alleviating immune-mediated hepatitis: A novel immunomodulatory non-immunosuppressive formulation for treatment of immune-mediated disorders: Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Tawfik Khoury, Yuval Ishay, Devorah Rotnemer-Golinkin, Lidya Zolotarovya, David Arkadir, Ari Zimran, Yaron IlanFigures (5)Biomedicine & PharmacotherapyVolume 132, December 2020, 110890A synergistic…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:58

Evaluation of anti-inflammatory and immunoregulatory activities of Stimunex® and Stimunex D3® in human monocytes/macrophages stimulated with LPS or IL-4/IL-13
Evaluation of anti-inflammatory and immunoregulatory activities of Stimunex® and Stimunex D3® in human monocytes/macrophages stimulated with LPS or IL-4/IL-13: Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Cristina Aguzzi, Oliviero Marinelli, Laura Zeppa, Giorgio Santoni, Filippo Maggi, Massimo NabissiFigures (10)Show all figuresExtras (2)Download allDocumentDocumentBiomedicine & PharmacotherapyVolume 132, December 2020, 110845Original articleEvaluation…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:56

Utility of NKX3.1 immunohistochemistry in the differential diagnosis of seminal vesicles versus prostatic tissue in needle biopsy
Utility of NKX3.1 immunohistochemistry in the differential diagnosis of seminal vesicles versus prostatic tissue in needle biopsy: Publication date: Available online 17 October 2020Source: Annals of Diagnostic PathologyAuthor(s): Pitra Tomas, Pivovarcikova Kristyna, Alaghehbandan Reza, Eva Maria Compérat, Hora Milan, Joanna Rogala, Maryna Slisarenko, Michal Michal, Hes OndrejFigures (4)Annals of Diagnostic PathologyAvailable online 17 October 2020, 151644In Press, Journal Pre-proofWhat are Journal…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:54

Association between carbonic anhydrase 9 expression and poor prognosis in sinonasal squamous cell carcinoma
Association between carbonic anhydrase 9 expression and poor prognosis in sinonasal squamous cell carcinoma: Publication date: Available online 17 October 2020Source: Annals of Diagnostic PathologyAuthor(s): Chunyan Hu, Huan Wang, Lan Lin, Xicai Sun, Dehui WangFigures (2)Tables (4)Table 1Table 2Table 3Table 4Annals of Diagnostic PathologyAvailable online 17 October 2020, 151643In Press, Journal Pre-proofWhat are Journal Pre-proof articles?Original ContributionAssociation between carbonic anhydrase…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:54

Structural remodeling of the lumbar multifidus, thoracolumbar fascia and lateral abdominal wall perimuscular connective tissues: A search for its potential determinants
Structural remodeling of the lumbar multifidus, thoracolumbar fascia and lateral abdominal wall perimuscular connective tissues: A search for its potential determinants: Determinants that influence remodeling of lumbar soft tissues need to be elucidated in order to understand the impact of different rehabilitation modalities. While age, sex and pain status explain some variability, modifiable factors such as physical activity level as well as trunk muscle thickness and function were involved. These…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:53

Ultrastructural evidence for telocytes in equine tendon
Ultrastructural evidence for telocytes in equine tendon: This study describes the characteristics of telocytes, located near blood vessels, in the equine tendon. Telocytes may represent an early step in the tendon‐derived stem cell differentiation process towards mature tenocytes “in vivo” based on a previous hypothesis that highlights telocytes as potential mesenchymal progenitor cells. Of particular interest is the presence of the primary cilium as a signalling antenna involved in tenocyte differentiation.AbstractThe…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:52

Blood oxygenation level dependent magnetic resonance imaging and diffusion weighted MRI imaging for benign and malignant breast cancer discrimination
Blood oxygenation level dependent magnetic resonance imaging and diffusion weighted MRI imaging for benign and malignant breast cancer discrimination: Publication date: Available online 17 October 2020Source: Magnetic Resonance ImagingAuthor(s): Roberta Fusco, Vincenza Granata, Paolo Pariante, Vincenzo Cerciello, Claudio Siani, Maurizio Di Bonito, Marika Valentino, Mario Sansone, Gerardo Botti, Antonella PetrilloAbstractPurposeThe purpose of this study is to assess Blood oxygenation level dependent…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:52

Scalp ripples can predict development of epilepsy
Scalp ripples can predict development of epilepsy after first unprovoked seizure in childhood: ObjectiveIdentification of children at risk of developing epilepsy after a first unprovoked seizure can be challenging. Interictal epileptiform discharges are associated with higher risk but have limited sensitivity and specificity. High frequency oscillations (HFOs) are newer biomarkers for epileptogenesis. We prospectively evaluated the predictive value of HFOs for developing epilepsy in scalp EEG of…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:50

Outcomes of Pre-Early Treatment for Retinopathy of Prematurity
Outcomes of Pre-Early Treatment for Retinopathy of Prematurity (Pre-ETROP): Authors Titawattanakul Y, Kulvichit K, Varadisai A, Mavichak AReceived 16 July 2020Accepted for publication 24 September 2020Published 16 October 2020 Volume 2020:14 Pages 3393—3397DOI https://doi.org/10.2147/OPTH.S268997Checked for plagiarism YesReview by Single anonymous peer reviewPeer reviewer comments 2Editor who approved publication: Dr Scott FraserYothin Titawattanakul, Kittisak Kulvichit, Adisai Varadisai, Apivat…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:47

Long-Term Effects of Botulinum Toxin in Large-Angle Infantile Esotropia
Long-Term Effects of Botulinum Toxin in Large-Angle Infantile Esotropia: Authors Gallo FG, Plaitano C, Esposito Veneruso P, Magli AReceived 8 July 2020Accepted for publication 18 August 2020Published 19 October 2020 Volume 2020:14 Pages 3399—3402DOI https://doi.org/10.2147/OPTH.S266652Checked for plagiarism YesReview by Single anonymous peer reviewPeer reviewer comments 2Editor who approved publication: Dr Scott FraserFlavio Gioele Gallo,1 Carmen Plaitano,2 Paolo Esposito Veneruso,3 Adriano Magli11Department…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:47

Selection for increased tibia length alters skull shape
Selection for increased tibia length in mice alters skull shape through parallel changes in developmental mechanisms [NEW RESULTS]: Bones in the vertebrate cranial base and limb skeleton grow by endochondral ossification, under the control of growth plates. Mechanisms of endochondral ossification are conserved across growth plates, which increases covariation in size and shape among bones, and in turn may lead to correlated changes in skeletal traits not under direct selection. We used micro-CT and…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:46

Phaeochromocytoma recurrence
Phaeochromocytoma recurrence in a patient with multiple endocrine neoplasia type 2A: AbstractMultiple endocrine neoplasia type 2A (MEN2A) is a hereditary syndrome associated with tumours of the endocrine system. Principally, it is characterized by medullary thyroid carcinoma (MTC) with some individuals also developing phaeochromocytoma and hyperparathyroidism. Patients with fewer than two clinical features require either an identification of a germline rearranged in transfection mutation, or MEN2A…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:44

Iatrogenically displaced third molar into the maxillary sinus
Presentation of an iatrogenically displaced third molar into the maxillary sinus in a 14-year-old patient successfully removed with an endoscopic approach: a case report and a review of the literature: AbstractOral surgeons remove third molars (wisdom teeth) to prevent impaction. Given the close anatomical relationship to the maxillary sinus, perforation and displacement of third molars into the maxillary sinus is a well-known phenomenon that is typically removed with a buccal mucoperiosteal flap…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:43

Unligated vertical vein presenting as a large atrio-portal shunt in adulthood
Unligated vertical vein presenting as a large atrio-portal shunt in adulthood: a case report: AbstractA 28-year-old male with infra-cardiac totally anomalous pulmonary venous connection (TAPVC) repaired as new-born presented in adulthood with right heart strain and very large left atrium to portal vein vessel. Residual connections from pulmonary veins to systemic circulation are believed to represent persistent ‘vertical veins’ (VV) not ligated at the time of the initial surgery. In our patient,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:42

Upper limb phlegmasia cerulea dolens
Upper limb phlegmasia cerulea dolens treated with single-session suction thrombectomy: a case report: AbstractPhlegmasia cerulea dolens (PCD) of the lower limbs is a rare condition. PCD of the upper limbs is extremely uncommon, with only a select few cases documented in the literature. A complication of severe deep venous thrombosis, PCD, is characterized by the clinical triad of oedema, pain and limb cyanosis. Delays in treatment are associated with high rates of morbidity and mortality. We present…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:41

Long-term disease burden of intracranial meningioma
Determinants and predictors for the long-term disease burden of intracranial meningioma patients03:00via Neuro-OncologyAbstractIntroductionMeningioma is a heterogeneous disease and patients may suffer from long-term tumor- and treatment-related sequelae. To help identify patients at risk for these late effects, we first assessed variables associated with impaired long-term health-related quality of life (HRQoL) and impaired neurocognitive function on group level (i.e. determinants). Next, prediction…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:37

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
SAGE Publications: Journal of Investigative Medicine High Impact Case Reports: Table of ContentsBridging the Divisum: A Rare Case of Pancreaticopleural Fistula in the Setting of Complete Pancreatic Divisum Treated EndoscopicallyJournal of Investigative Medicine High Impact Case Reports, Volume 8, Issue , January-December 2020. A pancreaticopleural fistula (PPF) is a rare complication of chronic pancreatitis that occurs either due to a pancreatic duct disruption or a pseudocyst extension. A pancreatic…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:27

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
Medical OncologyThe clinical significance of CD49e and CD56 for multiple myeloma in the novel agents eraAbstract Multiple myeloma (MM) is a hematological malignancy characterized by the proliferation of abnormal plasma cells in bone marrow. Flow cytometry distinguishes between normal and abnormal plasma cells by evaluating cluster of differentiation (CD) 56 and CD19 expression patterns. Moreover, immunophenotyping of mature plasma cell 1 (MPC-1) and very late antigen-5 (CD49e) identifies the maturity…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:26

Αφαίρεση διαφημίσεων


Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
Radiation Oncology – Latest ArticlesEvaluation of OAR dose sparing and plan robustness of beam-specific PTV in lung cancer IMRT treatmentMargins are employed in radiotherapy treatment planning to mitigate the dosimetric effects of geometric uncertainties for the clinical target volume (CTV). Here, we proposed a margin concept that takes into co…Radiation Oncology – Latest ArticlesSat Oct 17, 2020 03:00A non-invasive ultrasound imaging method to measure acute radiation-induced bladder wall thickening…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:25

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
Hearing ResearchHearing and Speech Processing in MidlifePublication date: Available online 17 October 2020Source: Hearing ResearchAuthor(s): Karen S. Helfer, Alexandra JesseHearing ResearchSun Oct 18, 2020 18:18“Translational Implications of the Interactions Between Hormones and Age-Related Hearing Loss”Publication date: Available online 15 October 2020Source: Hearing ResearchAuthor(s): R.D. Frisina, P. Bazard, M. Bauer, J. Pineros, X. Zhu, B. DingHearing ResearchFri Oct 16, 2020 17:48Cochlear…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:23

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
bioRxiv Subject Collection: Evolutionary BiologyIndividual variation in parental care drives divergence of sex roles [NEW RESULTS]In many animal species, parents provide care for their offspring, but the parental roles of the two sexes differ considerably between and within species. Here, we use an individual-based simulation approach to investigate the evolutionary emergence and stability of parental roles. Our conclusions are in striking contrast to the results of analytical models. In the absence…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:20

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
NutrientsNutrients, Vol. 12, Pages 3185: The Cardiotonic Steroid Marinobufagenin Is a Predictor of Increased Left Ventricular Mass in Obesity: The African-PREDICT StudyNutrients, Vol. 12, Pages 3185: The Cardiotonic Steroid Marinobufagenin Is a Predictor of Increased Left Ventricular Mass in Obesity: The African-PREDICT Study Nutrients doi: 10.3390/nu12103185 Authors: Michél Strauss-Kruger Ruan Kruger Wayne Smith Lebo F. Gafane-Matemane Gontse Mokwatsi Wen Wei Olga V. Fedorova Aletta E. Schutte…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:18

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
Journal of Clinical MedicineJCM, Vol. 9, Pages 3332: The Eye as a Non-Invasive Window to the Microcirculation in Liver Cirrhosis: A Prospective Pilot StudyJCM, Vol. 9, Pages 3332: The Eye as a Non-Invasive Window to the Microcirculation in Liver Cirrhosis: A Prospective Pilot Study Journal of Clinical Medicine doi: 10.3390/jcm9103332 Authors: Fiona J Gifford Francesca Moroni Tariq E Farrah Kirstie Hetherington Tom J MacGillivray Peter C Hayes Neeraj Dhaun Jonathan A Fallowfield Microcirculatory…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:16

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
HealthcareHealthcare, Vol. 8, Pages 409: Suitability of Ultra-Short-Term Heart Rate Variability in Military TraineesHealthcare, Vol. 8, Pages 409: Suitability of Ultra-Short-Term Heart Rate Variability in Military Trainees Healthcare doi: 10.3390/healthcare8040409 Authors: Mubarak J. Alalyan Shaea A. Alkahtani Syed Shahid Habib Andrew A. Flatt We aimed to (a) evaluate the agreement between ultra-short-term and criterion resting heart rate variability (HRV) measures in military trainees, and (b)…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:14

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
AntibioticsAntibiotics, Vol. 9, Pages 713: Preoperative Antibiotic Prophylaxis in Elective Minor Surgical Procedures among Adults in Southern ItalyAntibiotics, Vol. 9, Pages 713: Preoperative Antibiotic Prophylaxis in Elective Minor Surgical Procedures among Adults in Southern Italy Antibiotics doi: 10.3390/antibiotics9100713 Authors: Giorgia Della Polla Aida Bianco Silvia Mazzea Francesco Napolitano Italo Francesco Angelillo Little is known regarding the factors associated with surgical antibiotic…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:12

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
Frontiers in Oncology | New and Recent ArticlesSintilimab, a PD-1 Inhibitor, Completely Reversed Rarely Refractory Hypofibrinogenemia in a Gastric Cancer Patient: A Case Report and Review of the LiteratureWhile cancer is often related to hyperfibrinogenemia, it is rarely related to hypofibrinogenemia. Specifically, gastric cancer concomitant with unprovoked hypofibrinogenemia and the corresponding treatment approach have been rarely reported. We presented a case of gastric cancer in a 78-year-old…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:11

Σήμανση της παραπάνω ενότητας ως αναγνωσμένης

Nanomaterials

Nanomaterials, Vol. 10, Pages 2058: Perfluoropolyether Nanoemulsion Encapsulating Chlorin e6 for Sonodynamic and Photodynamic Therapy of Hypoxic Tumor
Nanomaterials, Vol. 10, Pages 2058: Perfluoropolyether Nanoemulsion Encapsulating Chlorin e6 for Sonodynamic and Photodynamic Therapy of Hypoxic Tumor Nanomaterials doi: 10.3390/nano10102058 Authors: Liang Hong Artem M. Pliss Ye Zhan Wenhan Zheng Jun Xia Liwei Liu Junle Qu Paras N. Prasad Sonodynamic therapy (SDT) has emerged as an important modality for cancer treatment. SDT utilizes ultrasound excitation, which overcomes the limitations of light penetration in…

Nanomaterials

03:00

Nanomaterials, Vol. 10, Pages 2059: Twin Domain Structure in Magnetically Doped Bi2Se3 Topological Insulator
Nanomaterials, Vol. 10, Pages 2059: Twin Domain Structure in Magnetically Doped Bi2Se3 Topological Insulator Nanomaterials doi: 10.3390/nano10102059 Authors: Jakub Šebesta Karel Carva Dominik Kriegner Jan Honolka Twin domains are naturally present in the topological insulator Bi2Se3 and strongly affect its properties. While studies of their behavior in an otherwise ideal Bi2Se3 structure exist, little is known about their possible interaction with other defects. Extra information…

Nanomaterials

03:00

Σήμανση της παραπάνω ενότητας ως αναγνωσμένης

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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia,

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Medicine by Alexandros G. Sfakianakis

Medicine by Alexandros G. Sfakianakis

Role of Pharmacists in Hormonal Contraceptive Access
Pharmacy, Vol. 8, Pages 191: Role of Pharmacists in Hormonal Contraceptive Access: A Survey of North Carolina Pharmacists: Pharmacy, Vol. 8, Pages 191: Role of Pharmacists in Hormonal Contraceptive Access: A Survey of North Carolina PharmacistsPharmacy doi: 10.3390/pharmacy8040191Authors: Gwen J Seamon Allison Burke Casey R Tak Amy Lenell Macary Weck Marciniak Mollie Ashe Scott The role of pharmacy in healthcare continues to evolve as pharmacists gain increased clinical responsibilities…

Medicine by Alexandros G. Sfakianakis

09:15

Cystocele Repair by a Modified Surgical Technique of Bilateral Pubococcygeus Plication: Long-Term Surgical and Functional Results
JCM, Vol. 9, Pages 3318: Cystocele Repair by a Modified Surgical Technique of Bilateral Pubococcygeus Plication: Long-Term Surgical and Functional Results: JCM, Vol. 9, Pages 3318: Cystocele Repair by a Modified Surgical Technique of Bilateral Pubococcygeus Plication: Long-Term Surgical and Functional ResultsJournal of Clinical Medicine doi: 10.3390/jcm9103318Authors: Matteo Balzarro Emanuele Rubilotta Alessandro Antonelli Here we describe our modified surgical technique of bilateral pubococcygeus…

Medicine by Alexandros G. Sfakianakis

09:14

Detection of Usutu virus infection in wild birds
Detection of Usutu virus infection in wild birds in the United Kingdom, 2020: In August 2020, as part of a long-term disease surveillance programme, Usutu virus was detected in five Eurasian blackbirds (Turdus merula) and one house sparrow (Passer domesticus) from Greater London, England. This was initially detected by reverse transcription-PCR and was confirmed by virus isolation and by immunohistochemical detection of flavivirus in tissues. Phylogenetic analysis identified Usutu virus African 3.2…

Medicine by Alexandros G. Sfakianakis

09:13

Detection and discrimination of influenza B Victoria lineage deletion variant viruses by real-time RT-PCR
Detection and discrimination of influenza B Victoria lineage deletion variant viruses by real-time RT-PCR: Background During the 2016/17 influenza season, influenza B/VIC lineage variant viruses emerged with two (K162N163) or three (K162N163D164) amino acid (aa) deletions in the haemagglutinin (HA) protein. There are currently five antigenically distinct HA proteins expressed by co-circulating influenza B viruses: B/YAM, B/VIC V1A (no deletion), B/VIC V1A-2DEL (2 aa deletion) and two antigenically…

Medicine by Alexandros G. Sfakianakis

09:13

Neisseria gonorrhoeae isolates
Molecular epidemiological typing of Neisseria gonorrhoeae isolates identifies a novel association between genogroup G10557 (G7072) and decreased susceptibility to cefixime, Germany, 2014 to 2017: Background Emerging antimicrobial resistance (AMR) challenges gonorrhoea treatment and requires surveillance.Aim This observational study describes the genetic diversity of Neisseria gonorrhoeae isolates in Germany from 2014 to 2017 and identifies N. gonorrhoeae multi-antigen sequence typing (NG-MAST)…

Medicine by Alexandros G. Sfakianakis

09:13

Short-term outcomes after a neonatal arterial ischemic stroke
Short-term outcomes after a neonatal arterial ischemic stroke: AbstractPurposeThe purpose of this study is to determine the frequency and radiological predictors of recurrent acute symptomatic seizures (RASS) and motor impairment at discharge after a neonatal arterial ischemic stroke (NAIS). MethodsIn a nonconcurrent cohort study, 33 full-term newborns with NAIS confirmed by MRI are admitted into our hospital between January 2003 and December 2012. Stroke size, calculated as…

Medicine by Alexandros G. Sfakianakis

09:12

Down–regulating miR-217-5p Protects Cardiomyocytes against Ischemia/Reperfusion Injury by Restoring Mitochondrial Function via Targeting SIRT1
Down–regulating miR-217-5p Protects Cardiomyocytes against Ischemia/Reperfusion Injury by Restoring Mitochondrial Function via Targeting SIRT1: Abstract Downregulating miR-217-5p could protect cardiomyocytes against ischemia/reperfusion (I/R) injury, but its role in restoring mitochondrial function of I/R-injured cardiomyocytes remained unclear. H9C2 cardiomyocyte-derived cell line with I/R injury was established in vitro on the basis of hypoxia/reperfusion…

Medicine by Alexandros G. Sfakianakis

09:11

Age- and movement-related modulation of cortical oscillations in a mouse model of presbycusis
Age- and movement-related modulation of cortical oscillations in a mouse model of presbycusis: Publication date: Available online 15 October 2020Source: Hearing ResearchAuthor(s): J.A. Rumschlag, J.W. Lovelace, K.A. RazakFigures (8)Show all figuresTables (3)Table 1Table 2Table 3Hearing ResearchAvailable online 15 October 2020, 108095In Press, Journal Pre-proofWhat are Journal Pre-proof articles?Age- and movement-related modulation of cortical oscillations in a mouse model of presbycusisAuthor links…

Medicine by Alexandros G. Sfakianakis

09:11

Sialic acids expression in newborn rat lungs: implications for pulmonary developmental biology
Sialic acids expression in newborn rat lungs: implications for pulmonary developmental biology: Publication date: December 2020Source: Acta Histochemica, Volume 122, Issue 8Author(s): Maria de Fátima Martins, Ana Honório-Ferreira, Marco S. Reis, Catarina Cortez-Vaz, Carlos Alberto GonçalvesFigures (4)Tables (3)Table 1Table 2Table 3Acta HistochemicaVolume 122, Issue 8, December 2020, 151626Sialic acids expression in newborn rat lungs: implications for pulmonary developmental biologyAuthor links open…

Medicine by Alexandros G. Sfakianakis

09:10

Penetrating Midface Trauma
Penetrating Midface Trauma: A Case Report, Review of the Literature, and a Diagnostic and Management Protocol: Publication date: Available online 14 October 2020Source: Journal of Oral and Maxillofacial SurgeryAuthor(s): Eric Holmgren, Derrek Schartz, Nithya Puttige Ramesh, Kimutai Sylvester, Clifford Eskeyigures (11)Show all figuresTables (3)Table 1Table 2Table 3Journal of Oral and Maxillofacial SurgeryAvailable online 14 October 2020In Press, Uncorrected ProofWhat are Uncorrected Proof articles?Craniomaxillofacial…

Medicine by Alexandros G. Sfakianakis

09:09

Leukocyte and platelet-rich fibrin have same effect as blood clot in the three-dimensional alveolar ridge preservation. A split-mouth randomized clinical trial
Leukocyte and platelet-rich fibrin have same effect as blood clot in the three-dimensional alveolar ridge preservation. A split-mouth randomized clinical trial: Publication date: Available online 15 October 2020Source: Journal of Oral and Maxillofacial SurgeryAuthor(s): Pedro Christian Aravena, Stephania Pilar Sandoval, Felipe Eduardo Pizarro, María Isabel Simpson, Nicolás Castro-Adams, Guillaume Serandour, Cristian Rosas

Medicine by Alexandros G. Sfakianakis

09:08

Permanent iodine-125 implantation with or without external beam radiation therapy
Effect of adding androgen deprivation therapy to permanent iodine-125 implantation with or without external beam radiation therapy on the outcomes in patients with intermediate-risk prostate cancer: A propensity score–matched analysis<a name="bfn1" href="#fn1" aria-label="open footnote" id="crosref0010">¹</a>: Publication date: Available online 14 October 2020Source: BrachytherapyAuthor(s): Shinya Sutani, Atsunori Yorozu, Kazuhito Toya, Yutaka Shiraishi, Toru Nishiyama,…

Medicine by Alexandros G. Sfakianakis

09:07

Radiotherapy or brachytherapy after resection of primary adenoid cystic carcinoma in oral and maxillofacial regions
Comparison of outcomes using radiotherapy or brachytherapy after resection of primary adenoid cystic carcinoma in oral and maxillofacial regions: Publication date: Available online 14 October 2020Source: BrachytherapyAuthor(s): C. Li, S.M. Liu, L. Zheng, M.W. Huang, Y. Shi, X.M. Lv, J.G. Zhang, X. Peng, J. Zhang

Medicine by Alexandros G. Sfakianakis

09:07

Identification of male infertility-related long non-coding RNAs and their functions based on a competing endogenous RNA network
Identification of male infertility-related long non-coding RNAs and their functions based on a competing endogenous RNA network: Journal of International Medical Research, Volume 48, Issue 10, October 2020. ObjectiveTo identify male infertility-related long non-coding (lnc)RNAs and an lncRNA-related competing endogenous (ce)RNA network.MethodsExpression data including 13 normospermic and eight teratozoospermic samples from postmortem donors were downloaded from the GEO database (GSE6872). The limma…

Medicine by Alexandros G. Sfakianakis

09:00

Spontaneous remission of untreated primary amyloidosis of the bladder
Spontaneous remission of untreated primary amyloidosis of the bladder after transurethral resection biopsy: a case report and literature review: Journal of International Medical Research, Volume 48, Issue 10, October 2020. We herein present a case involving a 23-year-old woman with gross hematuria. Cystoscopy revealed abnormal areas of the mucosa along the anterior and posterior bladder walls. These abnormalities were suspicious for neoplasia; however, a diagnosis was not established by subsequent…

Medicine by Alexandros G. Sfakianakis

08:59

Post‐herpetic neuralgia
Study on the related factors of post‐herpetic neuralgia in hospitalized patients with herpes zoster in Sichuan Hospital of Traditional Chinese Medicine based on big data analysis: AbstractBackgroundAlthough various factors were reported to be related to post‐herpetic neuralgia (PHN), studies based on adequate and comprehensive data were absent.MethodsData was extracted from cases of hospitalized patients with herpes zoster in dermatology department, Sichuan hospital of traditional Chinese medicine…

Medicine by Alexandros G. Sfakianakis

08:59

Atypical Bilateral Multifocal Congenital Toxoplasmosis Retinochoroiditis
Atypical Bilateral Multifocal Congenital Toxoplasmosis Retinochoroiditis: Case Report With Literature Review: Journal of Investigative Medicine High Impact Case Reports, Volume 8, Issue , January-December 2020. BackgroundToxoplasmosis gondii is ubiquitously present on earth and infection, including congenital infection, is common. Neurological, developmental, and ocular effects can be devastating in the congenital toxoplasmosis population. At present, there is no standard, nation-wide neonatal screening…

Medicine by Alexandros G. Sfakianakis

08:58

Massive Upper Gastrointestinal Bleeding Following LAMS (Lumen-Apposing Metal Stent) Placement
Massive Upper Gastrointestinal Bleeding Following LAMS (Lumen-Apposing Metal Stent) Placement: Journal of Investigative Medicine High Impact Case Reports, Volume 8, Issue , January-December 2020. Pancreatic pseudocyst is a common complication of pancreatitis. Pseudocysts may require decompression when they become painful, infected, or start compressing surrounding organs. Decompression is achieved by endoscopic cystogastrostomy. Recently, the use of lumen-apposing metal stent (LAMS) for cystogastrostomy…

Medicine by Alexandros G. Sfakianakis

08:58

Subacute Aspergillosis “Fungal Balls”
Subacute Aspergillosis “Fungal Balls” Complicating COVID-19: Journal of Investigative Medicine High Impact Case Reports, Volume 8, Issue , January-December 2020. Severe acute respiratory syndrome coronavirus-2 infection (SARS-CoV-2), commonly known as COVID-19 (coronavirus disease-2019), began in the Wuhan District of Hubei Province, China. It is regarded as one of the worst pandemics, which has consumed both human lives and the world economy. COVID-19 infection mainly affects the lungs triggering…

Medicine by Alexandros G. Sfakianakis

08:58

Eosinophilic Myocarditis
A Progressive Case of Eosinophilic Myocarditis Due to Eosinophilic Granulomatosis With Polyangiitis in a Caucasian Male: Journal of Investigative Medicine High Impact Case Reports, Volume 8, Issue , January-December 2020. Vasculitis is an inflammatory process involving blood vessels of various sizes, including the small vessels in the kidneys to the large vessels, such as the aorta. This inflammatory condition is usually autoimmune in nature and is associated with involvement of many locations, such…

Medicine by Alexandros G. Sfakianakis

08:57

Oxygen therapy strategies and techniques to treat hypoxia
Oxygen therapy strategies and techniques to treat hypoxia in COVID-19 patients: OBJECTIVE: Hypoxia is one of the primary causes that leads to multiple organ injuries and death in COVID-19 patients. Aggressive oxygen therapy for the treatment of hypoxia is important in saving these patients. We have summarized the mechanisms, efficacy, and side effects of various oxygen therapy techniques and their status or the potential to treat hypoxia in COVID-19 patients. The benefit to risk ratio of each oxygen…

Medicine by Alexandros G. Sfakianakis

08:57

Conventionally Versus Digitally Fabricated Denture
A Comparison of Conventionally Versus Digitally Fabricated Denture Outcomes in a University Dental Clinic: AbstractPurposeThe purpose of this retrospective, cross‐sectional study is to evaluate if there is a difference in number of visits (including fabrication and post‐operative) and remake rate when comparing conventionally fabricated and digitally fabricated complete dentures by dental students in a pre‐doctoral student dental clinic.Materials and MethodsThis two‐year retrospective cross‐sectional…

Medicine by Alexandros G. Sfakianakis

08:56

Lectin Drug Conjugate Therapy for Colorectal Cancer
Lectin Drug Conjugate Therapy for Colorectal Cancer: AbstractDrug resistance represents an obstacle in colorectal cancer treatment because of its association with poor prognoses. rBC2LCN is a lectin isolated from Burkholderia that binds cell surface glycans that have fucose moieties. Since fucosylation is often enhanced in many types of cancers, this lectin could be an efficient drug carrier if colorectal cancer cells specifically present such glycans. Therefore, we examined the therapeutic efficacy…

Medicine by Alexandros G. Sfakianakis

08:56

What causes hidradenitis suppurativa ?
What causes hidradenitis suppurativa ? – 15 years after: AbstractThe 14 authors of the first review article on hidradenitis suppurativa (HS) pathogenesis published 2008 in EXPERIMENTAL DERMATOLOGY cumulating from the 1st International Hidradenitis Suppurativa Research Symposium held March 30–April 2, 2006 in Dessau, Germany with 33 participants were prophetic when they wrote “Hopefully, this heralds a welcome new tradition: to get to the molecular heart of HS pathogenesis, which can only be achieved…

Medicine by Alexandros G. Sfakianakis

08:56

Genome‐wide association analysis of psoriasis patients treated with anti‐TNF drugs
Genome‐wide association analysis of psoriasis patients treated with anti‐TNF drugs: AbstractBackgroundWhile anti‐TNF therapies are effective against psoriasis, 30‐50% of patients do not show an adequate response to these drugs. Different candidate‐gene pharmacogenetics studies have identified single nucleotide polymorphisms that may predict anti‐TNF drugs response in psoriasis. Nevertheless, only one paper has undertaken a pharmacogenomic approach failing to find significant biomarkers of biological…

Medicine by Alexandros G. Sfakianakis

08:56

An active endoscope with small sweep volume that preserves image orientation for arthroscopic surgery
An active endoscope with small sweep volume that preserves image orientation for arthroscopic surgery: AbstractBackgroundMicrosurgery is generally performed in narrow spaces with limited movement. Endoscopes that allow for angle changes have been developed using elastic materials, but they require a large bending space. We propose a new endoscope with a small sweep volume for angle changes.MethodsWe fabricated a prototype with a thumb‐operated joystick. The image sensor is attached to the tooltip….

Medicine by Alexandros G. Sfakianakis

08:55

Emergency Airway Management During Awake Craniotomy
Emergency Airway Management During Awake Craniotomy: Comparison of 5 Techniques in a Cadaveric Model: Background: During awake craniotomy, securing the patient’s airway might be necessary electively or emergently. The objective of this study was to compare the feasibility of airway management using a laryngeal mask airway (LMA) and 4 alternative airway management techniques in an awake craniotomy simulation. Methods: After completing a questionnaire, 9 anesthesia providers attempted airway…

Medicine by Alexandros G. Sfakianakis

08:55

Electroencephalographic Alpha and Delta Oscillation Dynamics in Response to Increasing Doses of Propofol
Electroencephalographic Alpha and Delta Oscillation Dynamics in Response to Increasing Doses of Propofol: Background: The electroencephalogram (EEG) may be useful for monitoring anesthetic depth and avoiding overdose. We aimed to characterize EEG-recorded brain oscillations during increasing depth of anesthesia in a real-life surgical scenario. We hypothesized that alpha power and coherency will diminish as propofol dose increases between loss of consciousness (LOC) and an EEG burst suppression…

Medicine by Alexandros G. Sfakianakis

08:54

Role of Dexmedetomidine in Aneurysmal Subarachnoid Hemorrhage
Role of Dexmedetomidine in Aneurysmal Subarachnoid Hemorrhage: A Comprehensive Scoping Review: Dexmedetomidine (DEX), an α2-adrenergic agonist, has been widely used for anesthesia, pain control, and intensive care unit sedation. Besides sleep-like sedation, DEX has many other beneficial effects, such as anti-inflammation, antioxidation, and anticell death. Subarachnoid hemorrhage (SAH), a severe and potentially fatal form of stroke, is a complex disease that is divided into 2 phases: early brain…

Medicine by Alexandros G. Sfakianakis

08:54

A Curious Case of Persistent Throat Pain……a man in his 20s who presented with persistent, severe, right-sided, throbbing throat pain and dysphagia and was found to have bony mass in the parapharyngeal space following a tonsillectomy
A Curious Case of Persistent Throat Pain: This case report describes a man in his 20s who presented with persistent, severe, right-sided, throbbing throat pain and dysphagia and was found to have bony mass in the parapharyngeal space following a tonsillectomy.

Medicine by Alexandros G. Sfakianakis

08:53

Aerosol Transmission of Infectious Agents During Mastoid Drilling
A Cost-effective Solution to Limit Aerosol Transmission of Infectious Agents During Mastoid Drilling: To the Editor We were interested by the recent article by Carron, et al “A Simple Technique for Droplet Control During Mastoid Surgery” because we have also been considering the challenges of performing mastoidectomy in the coronavirus disease 2019 era. Mastoidectomy is an aerosol-generating procedure (AGP) owing to the use of drills and presence of potentially virus-containing respiratory mucosa…

Medicine by Alexandros G. Sfakianakis

08:52

Facial Nerve Intraneural Perineurioma
Facial Nerve Intraneural Perineurioma Masquerading as a Schwannoma: This case report describes a woman in her 30s who presented with worsening left-sided facial weakness and was diagnosed with a perineurioma.

Medicine by Alexandros G. Sfakianakis

08:52

a man in his 20s who presented with a 4-week history of progressive swelling of the midline forehead, recurrent headache, and sinus pain………………Atypical Presentation of Langerhans Cell Histiocytosis of the Skull
Atypical Presentation of Langerhans Cell Histiocytosis of the Skull: This case report describes a man in his 20s who presented with a 4-week history of progressive swelling of the midline forehead, recurrent headache, and sinus pain, and was subsequently diagnosed with Langerhans cell histiocytosis.

Medicine by Alexandros G. Sfakianakis

08:49

Eustachian Tube Rhabdomyomatous Mesenchymal Hamartoma in a Pediatric Patient
Eustachian Tube Rhabdomyomatous Mesenchymal Hamartoma in a Pediatric Patient: This case report describes a young girl who presented with a history of chronic, unilateral middle ear effusion that was treated with a pressure equalization tube.

Medicine by Alexandros G. Sfakianakis

08:48

Predictors of OSA following Adenotonsillectomy in Children with Trisomy 21
Predictors of OSA following Adenotonsillectomy in Children with Trisomy 21: AbstractObjectivesGiven that 30‐50% of children with trisomy 21 have persistent obstructive sleep apnea (OSA) after adenotonsillectomy, we evaluated whether demographic, clinical and polysomnographic factors predicted persistent OSA and OSA severity after adenotonsillectomy.DesignRetrospective study.SettingSecondary care hospital.ParticipantsRetrospective review of 32 children with the diagnosis of trisomy 21 and OSA by polysomnography…

Medicine by Alexandros G. Sfakianakis

08:47

Evaluation of cerebral arteriovenous shunts
Evaluation of cerebral arteriovenous shunts: a comparison of parallel imaging time-of-flight magnetic resonance angiography (TOF-MRA) and compressed sensing TOF-MRA to digital subtraction angiography: AbstractPurposeTime-of-flight (TOF)-MR angiography (MRA) is an important imaging sequence for the surveillance and analysis of cerebral arteriovenous shunt (AVS), including arteriovenous malformation (AVM) and arteriovenous fistula (AVF). However, this technique has the disadvantage of a relatively…

Medicine by Alexandros G. Sfakianakis

08:46

Activation of 5‐HT7 receptor but not NOS is necessary for chronic 5‐HT‐induced hypotension
Activation of 5‐HT7 receptor but not NOS is necessary for chronic 5‐HT‐induced hypotension: New FindingsWhat is the central question of this study? What mechanisms account for the hypotension observed during chronic elevations in circulating 5‐hydroxytryptamine in rats? What is the main finding and its importance? Chronic 5‐hydroxytryptamine induced hypotension requires continued activation of the 5‐HT7 receptor subtype but does not require NO, an outcome that resolves previous conflicting…

Medicine by Alexandros G. Sfakianakis

08:45

Sleep restriction alters physiological and emotional responses to emotion induction
Sleep restriction alters physiological and emotional responses to emotion induction: New FindingsThe aim of the present study was to assess the effects of sleep restriction on self report and autonomic responses to neutral and sad film clips. Ratings of sadness and heart rate deceleration were greater while watching the sad clip, with no effect of sleep restriction; whereas heart rate variability and skin conductance were impacted by sleep restriction and to a lesser extent by film clips. Results…

Medicine by Alexandros G. Sfakianakis

08:45

The acute effect of resistance exercise on limb blood flow
The acute effect of resistance exercise on limb blood flow: New FindingsWhat is the central question of this study? How does resistance exercise affect peripheral haemodynamics in the active and inactive limb? What is the main finding and its importance? Preliminary data indicate that resistance exercise increases flow and shear rate in the active limb transiently. The same exercise has minimal, short‐lasting influence on peripheral haemodynamics in the inactive limb, but further research is…

Medicine by Alexandros G. Sfakianakis

08:44

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Optimising sleep and performance during night float
Optimising sleep and performance during night float: A systematic review of evidence and implications for graduate medical education trainees: AbstractGraduate medical education (GME) training commonly requires residents and fellows to engage in night float shift work. This review aims to assess the effectiveness of interventions for trainees when preparing for, completing, and recovering from working night float shifts. We reviewed all available studies published prior to September 2019 using PubMed,…

Medicine by Alexandros G. Sfakianakis

08:44

Intestinal obstruction secondary to shiitake mushroom intake
A case series of intestinal obstruction secondary to shiitake mushroom intake during Chinese New Year: AbstractShiitake mushroom is a common ingredient in East Asian cuisines. Food processing/preparation can cause the mushroom to be soft and slimy, leading to accidental swallowing. Due to its high insoluble fibre content, it remains the same size and shape in the intestinal tract. We present two cases of small bowel obstruction caused by shiitake mushroom requiring surgical intervention. Preoperative…

Medicine by Alexandros G. Sfakianakis

08:44

Ankylosis of the temporomandibular joint
Ankylosis of the temporomandibular joint—impression free CAD/CAM based joint replacement using patient-specific implants: AbstractIn recent years, alloplastic temporomandibular joint (TMJ) replacement has become a permissible procedure for the reconstruction of severely destroyed TMJs. The use of computer-aided design/computer-aided manufacturing (CAD/CAM) has extended the range of applications to complex anatomical situations. The aim of the treatment is to improve the usually restricted mouth opening…

Medicine by Alexandros G. Sfakianakis

08:43

Effect of chitosan solutions with or without fluoride on the protection against dentin erosion in vitro
Effect of chitosan solutions with or without fluoride on the protection against dentin erosion in vitro: The aim of this study was to assess the protective effect of experimental solutions containing chitosan at different viscosities with or without fluoride (TiF4/NaF) on dentin loss in vitro. Bovine dentin samples (n = 15) were prepared and allocated to one of the following treatments: (i) 0.5% chitosan (500 mPas); (ii) 0.5% chitosan (2,000 mPas); (iii) 0.042% NaF and 0.049% TiF4; (iv) as (iii)…

Medicine by Alexandros G. Sfakianakis

08:43

Rosai‐Dorfman disease of the pancreas
Rosai‐Dorfman disease of the pancreas: Cytologic analysis of three cases presenting as pancreatic masses: AbstractRosai‐Dorfman Disease (RDD), or sinus histiocytosis with massive lymphadenopathy, is a rare entity characterized by proliferating S100‐positive histiocytes. It is most commonly found in lymph nodes with extranodal involvement usually occurring in the head and neck. Pancreatic involvement is extremely rare. The pathology department archives were searched for fine needle aspirations and…

Medicine by Alexandros G. Sfakianakis

08:43

Epilepsy and movement disorders in Congenital glycosylation disorders (CDG)
Epilepsy and movement disorders in CDG: Report on the oldest‐known MOGS‐CDG patient: AbstractCongenital glycosylation disorders (CDG) are inherited metabolic diseases due to defective glycoprotein and glycolipid glycan assembly and attachment. MOGS‐CDG is a rare disorder with seven patients from five families reported worldwide. We report on a 19‐year‐old girl with MOGS‐CDG. At birth she presented facial dysmorphism, marked hypotonia, and drug‐resistant tonic seizures. In the following months, her…

Medicine by Alexandros G. Sfakianakis

08:42

Novel GLI3 pathogenic variants in complex pre‐ and postaxial polysyndactyly and Greig cephalopolysyndactyly syndrome
Novel GLI3 pathogenic variants in complex pre‐ and postaxial polysyndactyly and Greig cephalopolysyndactyly syndrome: AbstractPolydactyly is a limb malformation and can occur as nonsyndromic polydactyly, syndromic polydactyly, or along with other limb defects. A few genes have been identified that cause various forms of syndromic and nonsyndromic polydactyly, of which GLI3 has been extensively explored. In the present study, GLI3 gene was screened by direct resequencing in 15 polydactyly cases with…

Medicine by Alexandros G. Sfakianakis

08:42

Multiple Cranial Neuropathies as the Presenting Sign in a Patient with Metastatic BRAF-Mutated Lung Adenocarcinoma with Leptomeningeal Involvement
Multiple Cranial Neuropathies as the Presenting Sign in a Patient with Metastatic BRAF-Mutated Lung Adenocarcinoma with Leptomeningeal Involvement: Leptomeningeal carcinomatosis accounts for only 4% of cases of multiple cranial neuropathies. Here, we report the case of a patient who presented with multiple synchronous cranial neuropathies. After treatment for neuroborreliosis and broad infectious workup, endobronchial ultrasound-guided mediastinal lymph node biopsy confirmed a diagnosis of metastatic…

Medicine by Alexandros G. Sfakianakis

08:41

RT-qPCR versus Digital PCR: How Do They Impact Differently on Clinical Management of Chronic Myeloid Leukemia Patients?
RT-qPCR versus Digital PCR: How Do They Impact Differently on Clinical Management of Chronic Myeloid Leukemia Patients?: Real-time quantitative PCR (RT-qPCR) is the gold standard to quantify the BCR-ABL1 transcript for molecular response monitoring in chronic myeloid leukemia (CML) patients, and it plays a pivotal role in clinical decision-making process, even if it presents technical limits. Increasing data suggest that digital PCR (dPCR) is more accurate and reliable than RT-qPCR in CML minimal…

Medicine by Alexandros G. Sfakianakis

08:40

Acquired Pure Red Cell Aplasia Associated with Chronic Myelomonocytic Leukemia: Too Many of One, Not Enough of the Other
Acquired Pure Red Cell Aplasia Associated with Chronic Myelomonocytic Leukemia: Too Many of One, Not Enough of the Other: There is a growing body of literature outlining the association between certain hematological malignancies, such as chronic myelomonocytic leukemia (CMML), and systemic autoimmune diseases. Diagnosis and management can be difficult, particularly when autoimmune phenomena overlap with features of the underlying illness. This is especially the case in patients who develop immune-mediated…

Medicine by Alexandros G. Sfakianakis

08:40

Microsatellite-Stable Radiation-Induced Angiosarcoma after Breast-Conserving Surgery: A Case Report
Microsatellite-Stable Radiation-Induced Angiosarcoma after Breast-Conserving Surgery: A Case Report: Radiation-induced angiosarcoma (RIAS) after breast-conserving surgery is quite rare. Risk factors for RIAS have yet to be identified, due largely to the very low incidence of this disease. The etiologic mechanisms of RIAS are not understood, although some reports suggest that genome instability may contribute to RIAS development. An 81-year-old Japanese woman presented to our hospital after developing…

Medicine by Alexandros G. Sfakianakis

08:40

physical activity (PA) and sedentary time (ST) with the combined outcome of incident stroke, myocardial infarction (MI)
Associations of Objectively Measured Physical Activity and Sedentary Time with the Risk of Stroke, Myocardial Infarction or All-Cause Mortality in 70-Year-Old Men and Women: A Prospective Cohort Study: AbstractObjectiveTo study the associations of objectively measured physical activity (PA) and sedentary time (ST) with the combined outcome of incident stroke, myocardial infarction (MI) or all-cause mortality in older adults. MethodsN = 3343 men and women aged 70 who participated…

Medicine by Alexandros G. Sfakianakis

08:40

Association among serum and salivary A. actinomycetemcomitans specific immunoglobulin antibodies and periodontitis
Association among serum and salivary A. actinomycetemcomitans specific immunoglobulin antibodies and periodontitis: AbstractBackgroundThe aim of this study was to assess the association between serum and salivary Immunoglobulin (Ig) Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans) specific antibodies in healthy controls (HC) and periodontitis (PT) patients. Furthermore, the objectives were to determine whether PT influenced serum A. actinomycetemcomitans specific antibodies and whether…

Medicine by Alexandros G. Sfakianakis

08:39

Rates of lymphocytic thyroiditis and ultrasound features
Rates of lymphocytic thyroiditis and ultrasound features of citologically-interrogated thyroid nodules based on the area of residence in a Sicily province: AbstractPurposeTo verify the prevalence of autoimmune thyroiditis (AIT) and the ultrasound characteristics (composition and volume) of thyroid nodules with respect to the area of residence in the province of Messina, some areas having environmental issues. MethodsFine-needle aspiration-interrogated nodules (n = 902) of 809…

Medicine by Alexandros G. Sfakianakis

08:38

The ketogenic diet corrects metabolic hypogonadism and preserves pancreatic ß-cell function in overweight/obese men: a single-arm uncontrolled study
The ketogenic diet corrects metabolic hypogonadism and preserves pancreatic ß-cell function in overweight/obese men: a single-arm uncontrolled study: AbstractBackgroundOverweight and obesity are increasingly spread in our society. Low testosterone levels are often present in these patients, the so-called metabolic hypogonadism, that further alters the metabolic balance in a sort of vicious cycle. Very low-calorie ketogenic diet (VLCKD) has been reported to efficiently reduce body weight, glycaemia,…

Medicine by Alexandros G. Sfakianakis

08:38

The effect of dual-release versus conventional hydrocortisone on fatigue
The effect of dual-release versus conventional hydrocortisone on fatigue, measured by ecological momentary assessments: AbstractPurposeReplicating the physiological cortisol secretion is key in the treatment of glucocorticoid insufficient individuals and optimization may enhance quality of life. The study investigates fatigue measured by ecological momentary assessments in patients treated with conventional hydrocortisone compared with once-daily dual-release hydrocortisone (Plenadren). …

Medicine by Alexandros G. Sfakianakis

08:38

Trichomegaly Associated with Panitumumab
Trichomegaly Associated with Panitumumab:

Medicine by Alexandros G. Sfakianakis

08:37

Vancomycin-Induced Linear IgA Bullous Dermatosis
Vancomycin-Induced Linear IgA Bullous Dermatosis:

Medicine by Alexandros G. Sfakianakis

08:36

Lymphocyte Variant Hypereosinophilic Syndrome With STAT3 SH2 Domain Mutations
Two Cases With Features of Lymphocyte Variant Hypereosinophilic Syndrome With STAT3 SH2 Domain Mutations: Lymphocyte variant hypereosinophilic syndrome (LV-HES) is a rare cause of eosinophilia that is due to eosinophilipoietic cytokine production by an immunophenotypically abnormal T-cell clone. The molecular pathogenesis of this disorder is largely unknown and only 1 case of LV-HES with a pathogenic STAT3 mutation has been described thus far. Here we report 2 cases of LV-HES with STAT3 SH2 domain…

Medicine by Alexandros G. Sfakianakis

08:36

Mural Intracholecystic Neoplasms Arising in Adenomyomatous Nodules of the Gallbladder: An Analysis of 19 Examples of a Clinicopathologically Distinct Entity
Mural Intracholecystic Neoplasms Arising in Adenomyomatous Nodules of the Gallbladder: An Analysis of 19 Examples of a Clinicopathologically Distinct Entity: Intracholecystic neoplasms (ICNs) (pyloric gland adenomas and intracholecystic papillary neoplasms, collectively also called intracholecystic papillary/tubular neoplasms) form multifocal, extensive proliferations on the gallbladder mucosa and have a high propensity for invasion (>50%). In this study, 19 examples of a poorly characterized…

Medicine by Alexandros G. Sfakianakis

08:35

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CT and FDG-PET radiologic biomarkers in p16+ oropharyngeal squamous cell carcinoma patients treated with definitive chemoradiotherapy
CT and FDG-PET radiologic biomarkers in p16+ oropharyngeal squamous cell carcinoma patients treated with definitive chemoradiotherapy: Survival among patients with human papilloma virus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC) is superior to those with non-HPV-associated OPSCC [1–3]. This is reflected in the most recent staging system, in which HPV-associated OPSCC is considered as a separate entity with unique TNM staging among head and neck cancers [4,5]. Although the standard…

Medicine by Alexandros G. Sfakianakis

08:35

Intrathoracic migration of ventriculo-peritoneal shunt via Morgagni hernia
Intrathoracic migration of ventriculo-peritoneal shunt via Morgagni hernia: AbstractWe present the case of a 5-month-old patient presenting with pleural migration of ventriculo-peritoneal shunt catheter who returned 2 months later with respiratory distress. Ultimately, the diagnosis of a Morgagni hernia was made. This diagnosis, though rare, should be entertained in certain clinical settings.

Medicine by Alexandros G. Sfakianakis

08:35

Application of 4D-CT Scanning in Differential Diagnosis of Arytenoid Subluxation and Vocal Fold Paralysis
Application of 4D-CT Scanning in Differential Diagnosis of Arytenoid Subluxation and Vocal Fold Paralysis: To differentiate arytenoid subluxation and vocal fold paralysis by CT cine mode scanning combined with three-dimensional (3D) reconstruction image.

Medicine by Alexandros G. Sfakianakis

08:34

Saponin from Periploca forrestii Schltr Mitigates Oxazolone-Induced Atopic Dermatitis via Modulating Macrophage Activation
Saponin from Periploca forrestii Schltr Mitigates Oxazolone-Induced Atopic Dermatitis via Modulating Macrophage Activation: Atopic dermatitis (AD) is a relapsing, acute, and chronic skin disease featured by intractable itching, eczematous skin. Conventional therapies based on immunosuppression such as corticosteroids are associated with multiple adverse reactions. Periploca forrestii Schltr saponin (PFS) was shown to potently inhibit murine arthritis by protecting bone and cartilage injury and suppressing…

Medicine by Alexandros G. Sfakianakis

08:34

Canakinumab in Patients with Adult-Onset Still’s Disease
Real-Life Data on the Efficacy of Canakinumab in Patients with Adult-Onset Still’s Disease: Background. Interleukin-1 inhibition has revealed to be a successful treatment approach for patients with adult-onset Still’s disease (AOSD). However, real-life experience is focused on the use of anakinra, while data about canakinumab (CAN) are mainly based on case reports and small case series. Patients and Methods. Patients classified with AOSD according to Yamaguchi criteria and treated with CAN were consecutively…

Medicine by Alexandros G. Sfakianakis

08:34

Surgical clip occlusion of the V3 segment to prevent recurrent cerebral infarction associated with extracranial vertebral artery dissection: A case report
Surgical clip occlusion of the V3 segment to prevent recurrent cerebral infarction associated with extracranial vertebral artery dissection: A case report: Surgical clip occlusion of the V3 segment to prevent recurrent cerebral infarction associated with extracranial vertebral artery dissection: A case report Category: Article Type: Ryo Aiura, Masaki Matsumoto, Tohru Mizutani, Tatsuya Sugiyama, Daisuke TaniokaDepartment of Neurosurgery, Showa University Hospital, Tokyo,…

Medicine by Alexandros G. Sfakianakis

08:33

Successful non-operative management for atlanto-occipital dislocation resulting in spinal cord contusion in a patient with atlanto-occipital assimilation and severe Chiari I malformation
Successful non-operative management for atlanto-occipital dislocation resulting in spinal cord contusion in a patient with atlanto-occipital assimilation and severe Chiari I malformation: Successful non-operative management for atlanto-occipital dislocation resulting in spinal cord contusion in a patient with atlanto-occipital assimilation and severe Chiari I malformation Category: Article Type: Jordan R. Davis1, Matthew L. Kluckman1, Grant W. Mallory2, John L. Ritter1Departments…

Medicine by Alexandros G. Sfakianakis

08:33

Biopsychosocial variations in quality of life outcome following microdiscectomy
Biopsychosocial variations in quality of life outcome following microdiscectomy: Biopsychosocial variations in quality of life outcome following microdiscectomy Category: Article Type: Lena Mary Houlihan, James Meeke, Orla Dunlea, Michael G. J. O’Sullivan, Chris Lim, George KaarDepartment of Neurosurgery, Cork University Hospital, Cork, Ireland.DOI:10.25259/SNI_449_2020Copyright: © 2020 Surgical Neurology International This is an open-access article distributed under the…

Medicine by Alexandros G. Sfakianakis

08:33

Primary Ewing’s sarcoma of the C2 vertebra with progressive quadriparesis: Report of a rare case and review of the literature
Primary Ewing’s sarcoma of the C2 vertebra with progressive quadriparesis: Report of a rare case and review of the literature: Primary Ewing’s sarcoma of the C2 vertebra with progressive quadriparesis: Report of a rare case and review of the literature Category: Article Type: Anandkumar Khatavi, Charanjit Singh Dhillon, Nilay Chhasatia, Chetan Pophale, Shafeek Nanakkal, Amit VarshneyDepartment of Spine, MIOT Hospital, Chennai, Tamil Nadu, India.DOI:10.25259/SNI_497_2020Copyright:…

Medicine by Alexandros G. Sfakianakis

08:32

Prevalence of intracranial aneurysms among acute ischemic stroke patients
Prevalence of intracranial aneurysms among acute ischemic stroke patients: Prevalence of intracranial aneurysms among acute ischemic stroke patients Category: Article Type: Jiroje Jiranukool1, Peeraphong Thiarawat1, Waneerat Galassi2Department of Neurosurgery, Naresuan University, Phitsanulok, Thailand.Department of Radiology, Naresuan University, Phitsanulok, Thailand.Correspondence Address:Jiroje JiranukoolDepartment of Radiology, Naresuan University, Phitsanulok, Thailand.DOI:10.25259/SNI_506_2020Copyright:…

Medicine by Alexandros G. Sfakianakis

08:32

Histopathological variation in the demyelinating sentinel lesion of primary central nervous system lymphoma
Histopathological variation in the demyelinating sentinel lesion of primary central nervous system lymphoma: Histopathological variation in the demyelinating sentinel lesion of primary central nervous system lymphoma Category: Article Type: Madan Bajagain1, Tatsuki Oyoshi1, Tomoko Hanada1, Nayuta Higa1, Tsubasa Hiraki2, Kiyohisa Kamimura3, Shinichi Kuroki1, Koji Yoshimoto1Departments of Neurosurgery, Graduate School of Medical and Dental Sciences, Kagoshima University,…

Medicine by Alexandros G. Sfakianakis

08:32

Surgical management of vertebral metastatic gastrointestinal stromal tumor: Case illustration, literature review, and pooled analysis
Surgical management of vertebral metastatic gastrointestinal stromal tumor: Case illustration, literature review, and pooled analysis: Surgical management of vertebral metastatic gastrointestinal stromal tumor: Case illustration, literature review, and pooled analysis Category: Article Type: Yu Tung Lo, David Siu Kei Mak, Colum Patrick NolanDepartment of Neurosurgery, National Neuroscience Institute, Singapore.DOI:10.25259/SNI_485_2020Copyright: © 2020 Surgical Neurology…

Medicine by Alexandros G. Sfakianakis

08:32

Radionuclide tumor necrosis factor-alpha activity in herniated lumbar disc correlates with severe leg pain
Radionuclide tumor necrosis factor-alpha activity in herniated lumbar disc correlates with severe leg pain: Radionuclide tumor necrosis factor-alpha activity in herniated lumbar disc correlates with severe leg pain Category: Article Type: Pablo Andrade1, Jasper van Aalst2, Matthias Bauwens3, Andreas Vogg4, Marinus J. van Kroonenburgh3, Felix M. Mottaghy3,4, Onno P. Teernstra2, Govert Hoogland2,5Department of Stereotactic and Functional Neurosurgery, University Hospital…

Medicine by Alexandros G. Sfakianakis

08:30

Successful mechanical thrombectomy using a combined technique for internal carotid artery occlusion with persistent primitive trigeminal artery
Successful mechanical thrombectomy using a combined technique for internal carotid artery occlusion with persistent primitive trigeminal artery: Successful mechanical thrombectomy using a combined technique for internal carotid artery occlusion with persistent primitive trigeminal artery Category: Article Type: Yoshinobu Horio1, Kenji Fukuda2, Takaya Yoshinaga1, Ryuhei Takeyama1, Hironori Fukumoto1, Kiminori Sato1, Yoshihisa Kawano1, Tooru Inoue2Department of Neurosurgery,…

Medicine by Alexandros G. Sfakianakis

08:29

Endoscopic-assisted paramedian infratentorial supracerebellar approach for pineal cyst – How I do it Video clip
Endoscopic-assisted paramedian infratentorial supracerebellar approach for pineal cyst – How I do it Video clip: Endoscopic-assisted paramedian infratentorial supracerebellar approach for pineal cyst – How I do it Video clip Category: Article Type: Riki Tanaka1, Kazuhito Takeuchi2, Ahmed Ansari3, Kento Sasaki1, Kyosuke Miyatani1, Yasuhiro Yamada1, Tsukasa Kawase1, Yoko Kato1, Akihiko Horiguchi4Department of Neurosurgery, Fujita Health University Banbuntane Hospital,Department…

Medicine by Alexandros G. Sfakianakis

08:29

The Latest on Uveal Melanoma Research and Clinical Trials: Updates from the Cure Ocular Melanoma (CURE OM) Science Meeting (2019)
The Latest on Uveal Melanoma Research and Clinical Trials: Updates from the Cure Ocular Melanoma (CURE OM) Science Meeting (2019): Uveal melanoma (UM) is a rare cancer in adults but its treatment is one of the clinical unmet needs in the melanoma field. Metastatic disease develops in approximately 50% of patients and is associated with poor survival due to the lack of effective treatment options. It provides a paradigm for cancers that show evidence of aberrant G-protein coupled receptor signaling,…

Medicine by Alexandros G. Sfakianakis

08:28

Hypo-fractionated FLASH-RT as an effective treatment against glioblastoma that reduces neurocognitive side effects in mice
Hypo-fractionated FLASH-RT as an effective treatment against glioblastoma that reduces neurocognitive side effects in mice: Purpose: Recent data has shown that single fraction irradiation delivered to the whole brain in less than tenths of a second using FLASH radiation therapy (RT), does not elicit neurocognitive deficits in mice. This observation has important clinical implications for the management of invasive and treatment-resistant brain tumors that involves relatively large irradiation volumes…

Medicine by Alexandros G. Sfakianakis

08:28

Comparison of Dynamic Contrast-Enhancement Parameters between Gadobutrol and Gadoterate Meglumine in Posttreatment Glioma: A Prospective Intraindividual Study [FUNCTIONAL]
Comparison of Dynamic Contrast-Enhancement Parameters between Gadobutrol and Gadoterate Meglumine in Posttreatment Glioma: A Prospective Intraindividual Study [FUNCTIONAL]: BACKGROUND AND PURPOSE:Differences in molecular properties between one-molar and half-molar gadolinium-based contrast agents are thought to affect parameters obtained from dynamic contrast-enhanced imaging. The aim of our study was to investigate differences in dynamic contrast-enhanced parameters between one-molar nonionic gadobutrol…

Medicine by Alexandros G. Sfakianakis

08:28

Centrally Reduced Diffusion Sign for Differentiation between Treatment-Related Lesions and Glioma Progression: A Validation Study [ADULT BRAIN]
Centrally Reduced Diffusion Sign for Differentiation between Treatment-Related Lesions and Glioma Progression: A Validation Study [ADULT BRAIN]: BACKGROUND AND PURPOSE:Differentiating between treatment-related lesions and tumor progression remains one of the greatest dilemmas in neuro-oncology. Diffusion MR imaging characteristics may provide useful information to help make this distinction. The aim of the study was to assess the diagnostic accuracy of the centrally reduced diffusion sign for differentiation…

Medicine by Alexandros G. Sfakianakis

08:27

Location-Specific ASPECTS Paradigm in Acute Ischemic Stroke
Location-Specific ASPECTS Paradigm in Acute Ischemic Stroke: A Systematic Review and Meta-Analysis [ADULT BRAIN]: BACKGROUND:Weighting neuroimaging findings based on eloquence can improve the predictive value of ASPECTS, possibly aiding in informed treatment decisions for acute ischemic stroke.PURPOSE:Our aim was to study the contribution of region-specific ASPECTS infarction to acute ischemic stroke outcomes.DATA SOURCES:We searched MEDLINE and EMBASE for reports on ASPECTS in patients with acute…

Medicine by Alexandros G. Sfakianakis

08:27

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Image-Guided Biopsies in the Head and Neck
Image-Guided Biopsies in the Head and Neck: Practical Value and Approach [COMMENTARIES]:

Medicine by Alexandros G. Sfakianakis

08:26

MRI-Based Assessment of the Pharyngeal Constrictor Muscle as a Predictor of Surgical Margin after Transoral Robotic Surgery in HPV-Positive Tonsillar Cancer [HEAD & NECK]
MRI-Based Assessment of the Pharyngeal Constrictor Muscle as a Predictor of Surgical Margin after Transoral Robotic Surgery in HPV-Positive Tonsillar Cancer [HEAD & NECK]: BACKGROUND AND PURPOSE:Transoral robotic surgery is an emerging strategy for treating human papillomavirus–positive cancers, but the role of MR imaging in predicting the surgical outcome has not been established. We aimed to identify preoperative MR imaging characteristics that predispose the outcome of transoral robotic surgery…

Medicine by Alexandros G. Sfakianakis

08:23

125I seeds irradiation inhibits tumor growth and induces apoptosis by Ki-67, P21, survivin, livin and caspase-9 expression in lung carcinoma xenografts
125I seeds irradiation inhibits tumor growth and induces apoptosis by Ki-67, P21, survivin, livin and caspase-9 expression in lung carcinoma xenografts: Lung cancer is a fatal disease and a serious health problem worldwide. Patients are usually diagnosed at an advanced stage, and the effectiveness of chemotherapy for such patients is very limited. Iodine 125 s…

Medicine by Alexandros G. Sfakianakis

08:23

Cranial Nerve III Palsy in the setting of COVID 19 Infection
Cranial Nerve III Palsy in the setting of COVID 19 Infection: No abstract available

Medicine by Alexandros G. Sfakianakis

08:23

TAM family receptors in conjunction with MAPK signalling are involved in acquired resistance to PI3Kα inhibition in head and neck squamous cell carcinoma
TAM family receptors in conjunction with MAPK signalling are involved in acquired resistance to PI3Kα inhibition in head and neck squamous cell carcinoma: Aberrant activation of the phosphatidylinositol 3-kinase (PI3K) pathway is common in many malignancies, including head and neck squamous cell carcinoma (HNSCC). Despite pre-clinical and clinical studies, outco…

Medicine by Alexandros G. Sfakianakis

08:22

5-methyltetrahydrofolate-based radioconjugates—new perspectives for folate receptor–targeted radionuclide therapy
Preclinical evaluation of 5-methyltetrahydrofolate-based radioconjugates—new perspectives for folate receptor–targeted radionuclide therapy: AbstractPurposeThe folate receptor (FR) is frequently overexpressed in a variety of tumor types and, hence, an interesting target for radionuclide therapy. The aim of this study was to evaluate a new class of albumin-binding radioconjugates comprising 5-methyltetrahydrofolate (5-MTHF) as a targeting agent and to compare their properties with those of the previously…

Medicine by Alexandros G. Sfakianakis

08:22

Recombinant human lactoferrin carrying humanized glycosylation exhibits antileukemia selective cytotoxicity, microfilament disruption, cell cycle arrest, and apoptosis activities
Recombinant human lactoferrin carrying humanized glycosylation exhibits antileukemia selective cytotoxicity, microfilament disruption, cell cycle arrest, and apoptosis activities: SummaryLactoferrin has gained extensive attention due to its ample biological properties. In this study, recombinant human lactoferrin carrying humanized glycosylation (rhLf-h-glycan) expressed in the yeast Pichia pastoris SuperMan5, which is genetically glycoengineered to efficiently produce functional humanized glycoproteins…

Medicine by Alexandros G. Sfakianakis

08:21

Donafenib in Progressive Locally Advanced or Metastatic Radioactive Iodine-Refractory Differentiated Thyroid Cancer: Results of a Randomized, Multicenter Phase II Trial
Donafenib in Progressive Locally Advanced or Metastatic Radioactive Iodine-Refractory Differentiated Thyroid Cancer: Results of a Randomized, Multicenter Phase II Trial: Thyroid, Ahead of Print.

Medicine by Alexandros G. Sfakianakis

08:21

Transcription Factor Profiling Identifies Spatially Heterogenous Mediators of Follicular Thyroid Cancer Invasion
Transcription Factor Profiling Identifies Spatially Heterogenous Mediators of Follicular Thyroid Cancer Invasion: AbstractWhile minimally invasive follicular thyroid cancer (miFTC) generally has low risk of recurrence or death, encapsulated angioinvasive (eaFTC) or widely invasive (wiFTC) histological subtypes display significantly worse prognosis. Drivers of invasion are incompletely understood. Therefore, tissue samples including miFTC, eaFTC, and wiFTC tumors, as well as histologically normal…

Medicine by Alexandros G. Sfakianakis

08:19

Differential effects of GABA A receptor activation in the prelimbic and orbitofrontal cortices on anxiety
Differential effects of GABA A receptor activation in the prelimbic and orbitofrontal cortices on anxiety: AbstractRationaleThe development of effective anxiety treatments has been hindered by limited understanding of the neurobiological mechanisms involved in anxiety regulation. Whilst gamma-aminobutyric acid (GABA) neurotransmission in the prefrontal cortex (PFC) is one mechanism consistently implicated in anxiety regulation, PFC subregions may contribute uniquely. ObjectivesThe…

Medicine by Alexandros G. Sfakianakis

08:19

Urothelial toxicity of esketamine in the treatment of depression
Urothelial toxicity of esketamine in the treatment of depression: AbstractRationaleKetamine is the first widely used substance with rapid-onset antidepressant action. However, there are uncertainties regarding its potential urothelial toxicity, particularly after repeated application. In the context of rising recreational ketamine use, severe side effects affecting the human urinary tract have been reported. It is assumed that ketamine interacts with bladder urothelial cells and induces apoptosis….

Medicine by Alexandros G. Sfakianakis

08:19

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
ScienceDirect Publication: TalantaGraphite-polystyrene composite with enhanced electrochemical and electroanalytical performancePublication date: Available online 15 October 2020Source: TalantaAuthor(s): Andrei M. Surkov, Rodrigo G. Queiroz, Rafael S. Rinco, Alejandro G. Rios Ivano G. R. Gutz, Alexandre L.B. Baccaro, Lúcio AngnesScienceDirect Publication: TalantaThu Oct 15, 2020 13:18Ionic-liquid doped polymeric composite as passive colorimetric sensor for meat freshness as a use casePublication…

Medicine by Alexandros G. Sfakianakis

08:18

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
BrachytherapyComparison of outcomes using radiotherapy or brachytherapy after resection of primary adenoid cystic carcinoma in oral and maxillofacial regionsPublication date: Available online 14 October 2020Source: BrachytherapyAuthor(s): C. Li, S.M. Liu, L. Zheng, M.W. Huang, Y. Shi, X.M. Lv, J.G. Zhang, X. Peng, J. ZhangBrachytherapyThu Oct 15, 2020 17:32Effect of adding androgen deprivation therapy to permanent iodine-125 implantation with or without external beam radiation therapy on the outcomes…

Medicine by Alexandros G. Sfakianakis

08:17

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
Climate change likely drove early human species to extinction, modeling study suggestsOf the six or more different species of early humans, all belonging to the genus Homo, only we Homo sapiens have managed to survive. Now, a study combining climate modeling and the fossil record in search of clues to what led to all those earlier extinctions suggests that climate change — the inability to adapt to either warming or cooling temperatures — likely played a major role in sealing their fate.Evolutionary…

Medicine by Alexandros G. Sfakianakis

08:15

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
bioRxiv Subject Collection: Evolutionary BiologySelfing is the safest sex for Caenorhabditis tropicalis [NEW RESULTS]Mating systems have profound effects on genetic diversity and compatibility. The convergent evolution of self-fertilization in three Caenorhabditis species provides a powerful lens to examine causes and consequences of mating system transitions. Among the selfers, C. tropicalis is the least genetically diverse and most afflicted by outbreeding depression. We generated a chromosomal-scale…

Medicine by Alexandros G. Sfakianakis

08:13

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
NanomaterialsNanomaterials, Vol. 10, Pages 2038: Comparative Study of Nanostructured CuSe Semiconductor Synthesized in a Planetary and Vibratory MillNanomaterials, Vol. 10, Pages 2038: Comparative Study of Nanostructured CuSe Semiconductor Synthesized in a Planetary and Vibratory Mill Nanomaterials doi: 10.3390/nano10102038 Authors: Marcela Achimovičová Matej Baláž Vladimír Girman Juraj Kurimský Jaroslav Briančin Erika Dutková Katarína Gáborová Copper(II) selenide, CuSe was prepared from Cu and…

Medicine by Alexandros G. Sfakianakis

08:11

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
International Journal of Molecular SciencesIJMS, Vol. 21, Pages 7642: Antineoplastic Activity of Chrysin against Human Hepatocellular Carcinoma: New Insight on GPC3/SULF2 Axis and lncRNA-AF085935 ExpressionIJMS, Vol. 21, Pages 7642: Antineoplastic Activity of Chrysin against Human Hepatocellular Carcinoma: New Insight on GPC3/SULF2 Axis and lncRNA-AF085935 Expression International Journal of Molecular Sciences doi: 10.3390/ijms21207642 Authors: Iman O. Sherif Laila A. Al-Mutabagani Dina Sabry Nehal…

Medicine by Alexandros G. Sfakianakis

08:10

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
International Journal of Environmental Research and Public HealthIJERPH, Vol. 17, Pages 7498: ICT-Enabled Mobile Work: Challenges and Opportunities for Occupational Health and Safety SystemsIJERPH, Vol. 17, Pages 7498: ICT-Enabled Mobile Work: Challenges and Opportunities for Occupational Health and Safety Systems International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17207498 Authors: Robelski Sommer The development and dissemination of new technologies has brought…

Medicine by Alexandros G. Sfakianakis

08:08

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
AntibioticsAntibiotics, Vol. 9, Pages 701: Antibiogram Profiles and Risk Factors for Multidrug Resistance of Salmonella enterica Recovered from Village Chickens (Gallus gallus domesticus Linnaeus) and Other Environmental Sources in the Central and Southern Peninsular MalaysiaAntibiotics, Vol. 9, Pages 701: Antibiogram Profiles and Risk Factors for Multidrug Resistance of Salmonella enterica Recovered from Village Chickens (Gallus gallus domesticus Linnaeus) and Other Environmental Sources in the…

Medicine by Alexandros G. Sfakianakis

08:07

Σήμανση της παραπάνω ενότητας ως αναγνωσμένης

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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia,

Telephone consultation 11855 int 1193,

Medicine by Alexandros G. Sfakianakis

Head and Neck Medicine by Alexandros G.Sfakianakis

Flow-Induced Transcriptomic Remodeling of Endothelial Cells Derived From Human Induced Pluripotent Stem Cells
Flow-Induced Transcriptomic Remodeling of Endothelial Cells Derived From Human Induced Pluripotent Stem Cells: The vascular system is essential for the development and function of all organs and tissues in our body. The molecular signature and phenotype of endothelial cells (EC) are greatly affected by blood flow-induced shear stress, which is a vital component of vascular development and homeostasis. Recent advances in differentiation of ECs from human induced pluripotent stem cells (hiPSC) have…

Head and Neck Medicine by Alexandros G.Sfakianakis

09:09

Two Undervalued Functions of the Golgi Apparatus: Removal of Excess Ca2+ and Biosynthesis of Farnesol-Like Sesquiterpenoids, Possibly as Ca2+-Pump Agonists and Membrane “Fluidizers–Plasticizers”
Two Undervalued Functions of the Golgi Apparatus: Removal of Excess Ca2+ and Biosynthesis of Farnesol-Like Sesquiterpenoids, Possibly as Ca2+-Pump Agonists and Membrane “Fluidizers–Plasticizers”: The extensive literature dealing with the Golgi system emphasizes its role in protein secretion and modification, usually without specifying from which evolutionary ancient cell physiological necessity such secretion originated. Neither does it specify which functional requirements the secreted proteins…

Head and Neck Medicine by Alexandros G.Sfakianakis

09:09

Physical Exercise and the Renin Angiotensin System: Prospects
Physical Exercise and the Renin Angiotensin System: Prospects in the COVID-19: Recent reports have shown that the renin angiotensin system (RAS) plays an important role in the Coronavirus disease 2019 (COVID-19) because the angiotensin converting enzyme 2 is the receptor for the severe acute respiratory syndrome coronavirus 2. In addition, the balance of RAS components can be involved in the pathogenesis and progression of COVID-19, especially in patients with metabolic and cardiovascular diseases….

Head and Neck Medicine by Alexandros G.Sfakianakis

09:08

Functional Characterization of Facilitative Glucose Transporter 4 With a Delay Responding to Plasma Glucose Level in Blunt Snout Bream (Megalobrama amblycephala)
Functional Characterization of Facilitative Glucose Transporter 4 With a Delay Responding to Plasma Glucose Level in Blunt Snout Bream (Megalobrama amblycephala): Facilitative glucose transporter 4 (GLUT4) plays a central role in mediating insulin function to increase glucose uptake in glucose metabolism homeostasis. In this study, the function and localization of GLUT4 in blunt snout bream (Megalobrama amblycephala) were first investigated, and then, the response measured as carbohydrate level,…

Head and Neck Medicine by Alexandros G.Sfakianakis

09:08

Palmitoyl Protein Thioesterase 1 Is Essential for Myogenic Autophagy of C2C12 Skeletal Myoblast
Palmitoyl Protein Thioesterase 1 Is Essential for Myogenic Autophagy of C2C12 Skeletal Myoblast: Skeletal muscle differentiation is an essential process for the maintenance of muscle development and homeostasis. Reactive oxygen species (ROS) are critical signaling molecules involved in muscle differentiation. Palmitoyl protein thioesterase 1 (PPT1), a lysosomal enzyme, is involved in removing thioester-linked fatty acid groups from modified cysteine residues in proteins. However, the role of PPT1…

Head and Neck Medicine by Alexandros G.Sfakianakis

09:07

Remodeling of the Microvasculature
Remodeling of the Microvasculature: May the Blood Flow Be With You: The vasculature ensures optimal delivery of nutrients and oxygen throughout the body, and to achieve this function it must continually adapt to varying tissue demands. Newly formed vascular plexuses during development are immature and require dynamic remodeling to generate well-patterned functional networks. This is achieved by remodeling of the capillaries preserving those which are functional and eliminating other ones. A balanced…

Head and Neck Medicine by Alexandros G.Sfakianakis

09:07

Effect of Hyperbilirubinemia on Medial Olivocochlear System in Newborns.
Effect of Hyperbilirubinemia on Medial Olivocochlear System in Newborns.: PMC7419097J Int Adv Otol. 2020 Aug; 16(2): 295–296.doi: 10.5152/iao.2020.8592PMCID: PMC7419097PMID: 32784171Effect of Hyperbilirubinemia on Medial Olivocochlear System in NewbornsFulya ÖzerAuthor information Article notes Copyright and License information DisclaimerDepartment of Oto-Rhino-Laryngology and Head Neck Surgery, Başkent University School of Medicine, Ankara, TurkeyCorresponding author.Corresponding Address: Fulya…

Head and Neck Medicine by Alexandros G.Sfakianakis

09:06

Preoperative assessment and optimization of cognitive dysfunction and frailty in the ambulatory surgical patient
Preoperative assessment and optimization of cognitive dysfunction and frailty in the ambulatory surgical patient: Purpose of review The number and the complexity of procedures taking place at ambulatory surgery centers is steadily increasing. The rate at which medically complex patients, including those with baseline neurocognitive disorders, are undergoing ambulatory procedures is seeing a concurrent rise. Given the significant physical and psychological stress associated with surgery even in…

Head and Neck Medicine by Alexandros G.Sfakianakis

09:05

High-risk surgical procedures and semi-emergent surgical procedures for ambulatory surgery
High-risk surgical procedures and semi-emergent surgical procedures for ambulatory surgery: Purpose of review This review evaluates more complex surgical procedures to see whether they might be suitable for ambulatory surgery. Operations that have shown an increasing daycase rate in England include thyroidectomy, joint arthroplasty, spinal surgery and hysterectomy, and these procedures are evaluated. Similarly, there have been recent developments in the management of nonelective ambulatory surgery…

Head and Neck Medicine by Alexandros G.Sfakianakis

09:04

Spinal anesthesia for ambulatory surgery: current controversies and concerns
Spinal anesthesia for ambulatory surgery: current controversies and concerns: Purpose of review General anesthesia is a popular choice for ambulatory surgery. Spinal anesthesia is often avoided because of perceived delays due to time required to administer it and prolonged onset, as well as concerns of delayed offset, which may delay recovery and discharge home. However, the reports of improved outcomes in hospitalized patients undergoing total joint arthroplasty have renewed the interest in spinal…

Head and Neck Medicine by Alexandros G.Sfakianakis

09:04

Peripheral nerve blockade and novel analgesic modalities for ambulatory anesthesia
Peripheral nerve blockade and novel analgesic modalities for ambulatory anesthesia: Purpose of review Despite peripheral nerve blockade offering analgesic benefits and improving patient satisfaction, it has not been well adopted in ambulatory anesthesia. In this review, we aim to summarize the evidence underlying peripheral nerve blockade, local anesthetic adjuncts, continuous peripheral nerve blockade and novel analgesic modalities, with the objective to provide recommendations on postoperative…

Head and Neck Medicine by Alexandros G.Sfakianakis

09:04

Noninvasive, continuous monitoring modalities in pediatric anesthesiology
Current state of noninvasive, continuous monitoring modalities in pediatric anesthesiology: Purpose of review The last decades, anesthesia has become safer, partly due to developments in monitoring. Advanced monitoring of children under anesthesia is challenging, due to lack of evidence, validity and size constraints. Most measured parameters are proxies for end organ function, in which an anesthesiologist is actually interested. Ideally, monitoring should be continuous, noninvasive and accurate….

Head and Neck Medicine by Alexandros G.Sfakianakis

09:03

The Bowtie diagram: a simple tool for analysis and planning in anesthesia
The Bowtie diagram: a simple tool for analysis and planning in anesthesia: Purpose of review The purpose is to show the advantages of a Bowtie diagram as a versatile tool for displaying and understanding the evolvement and management of critical incidents. Recent findings The Bowtie diagram has been used recently in anesthesia to depict critical incidents having been used in high-risk industries for several decades. This diagram displays the progression from latent factors to potential harm…

Head and Neck Medicine by Alexandros G.Sfakianakis

09:03

Maternal safety: recent advances and implications for the obstetric anesthesiologist
Maternal safety: recent advances and implications for the obstetric anesthesiologist: Purpose of review Recognition of the increasing maternal mortality rate in the United States has been accompanied by intense efforts to improve maternal safety. This article reviews recent advances in maternal safety, highlighting those of particular relevance to anesthesiologists. Recent findings Cardiovascular and other chronic medical conditions contribute to an increasing number of maternal deaths. Anesthetic…

Head and Neck Medicine by Alexandros G.Sfakianakis

09:02

Nulla Per Os (NPO) guidelines
Nulla Per Os (NPO) guidelines: time to revisit?: Purpose of review Preoperative fasting guidelines are generalized to elective procedures and usually do not distinguish between the ambulatory and inpatient setting. Prevalence of aspiration is low while prolonged preoperative fasting is common clinical reality. Recently, changes in preoperative fasting guidelines have been widely discussed. Recent findings Rates of prolonged clear fluid fasting (>4 h) prior to surgery are reported in up…

Head and Neck Medicine by Alexandros G.Sfakianakis

09:02

Measuring and monitoring perioperative patient safety: a basic approach for clinicians
Measuring and monitoring perioperative patient safety: a basic approach for clinicians: Purpose of review Recent research points to considerable rates of preventable perioperative patient harm and anaesthesiologists’ concerns about eroding patient safety. Anaesthesia has always been at the forefront of patient safety improvement initiatives. However, factual local safety improvement requires local measurement, which may be afflicted by barriers to data collection and improvement activities. Because…

Head and Neck Medicine by Alexandros G.Sfakianakis

09:01

Bacteria-derived long chain fatty acid exhibits anti-inflammatory properties in colitis.
Bacteria-derived long chain fatty acid exhibits anti-inflammatory properties in colitis.: Related ArticlesBacteria-derived long chain fatty acid exhibits anti-inflammatory properties in colitis.Gut. 2020 Sep 25;:Authors: Pujo J, Petitfils C, Le Faouder P, Eeckhaut V, Payros G, Maurel S, Perez-Berezo T, Van Hul M, Barreau F, Blanpied C, Chavanas S, Van Immerseel F, Bertrand-Michel J, Oswald E, Knauf C, Dietrich G, Cani PD, Cenac NAbstract OBJECTIVE: Data from clinical research suggest that…

Head and Neck Medicine by Alexandros G.Sfakianakis

09:01

Topic Application of the Probiotic Streptococcus dentisani
Topic Application of the Probiotic Streptococcus dentisani Improves Clinical and Microbiological Parameters Associated With Oral Health.: Related ArticlesTopic Application of the Probiotic Streptococcus dentisani Improves Clinical and Microbiological Parameters Associated With Oral Health.Front Cell Infect Microbiol. 2020;10:465Authors: Ferrer MD, López-López A, Nicolescu T, Perez-Vilaplana S, Boix-Amorós A, Dzidic M, Garcia S, Artacho A, Llena C, Mira AAbstract Streptococcus dentisani…

Head and Neck Medicine by Alexandros G.Sfakianakis

09:00

Probiotic effects on sperm parameters, oxidative stress index, inflammatory factors and sex hormones in infertile men.
Probiotic effects on sperm parameters, oxidative stress index, inflammatory factors and sex hormones in infertile men.: Related ArticlesProbiotic effects on sperm parameters, oxidative stress index, inflammatory factors and sex hormones in infertile men.Hum Fertil (Camb). 2020 Sep 27;:1-9Authors: Helli B, Kavianpour M, Ghaedi E, Dadfar M, Haghighian HKAbstract Decreased sperm motility is one of the main causes of male infertility. The aim of this study was to evaluate the effects of probiotic…

Head and Neck Medicine by Alexandros G.Sfakianakis

09:00

Effect of Limosilactobacillus reuteri LRE02-Lacticaseibacillus rhamnosus LR04 Combination on Antibiotic-Associated Diarrhea in a Pediatric Population: A National Survey.
Effect of Limosilactobacillus reuteri LRE02-Lacticaseibacillus rhamnosus LR04 Combination on Antibiotic-Associated Diarrhea in a Pediatric Population: A National Survey.: Effect of Limosilactobacillus reuteri LRE02-Lacticaseibacillus rhamnosus LR04 Combination on Antibiotic-Associated Diarrhea in a Pediatric Population: A National Survey.J Clin Med. 2020 Sep 24;9(10):Authors: Drago L, Meroni G, Chiaretti A, Laforgia N, Cucchiara S, Baldassarre ME, On Behalf Of The Surveyflor GroupAbstract …

Head and Neck Medicine by Alexandros G.Sfakianakis

08:59

Reduction of fatigue and anger-hostility by the oral administration of 5-aminolevulinic acid phosphate
Reduction of fatigue and anger-hostility by the oral administration of 5-aminolevulinic acid phosphate: a randomized, double-blind, placebo-controlled, parallel study.: Reduction of fatigue and anger-hostility by the oral administration of 5-aminolevulinic acid phosphate: a randomized, double-blind, placebo-controlled, parallel study.Sci Rep. 2020 Sep 29;10(1):16004Authors: Higashikawa F, Kanno K, Ogata A, Sugiyama MAbstract Although large populations feel fatigue, the standardized medicinal…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:59

Lactobacillus plantarum KSFY06 and geniposide counteract montmorillonite-induced constipation in Kunming mice.
Lactobacillus plantarum KSFY06 and geniposide counteract montmorillonite-induced constipation in Kunming mice.: Lactobacillus plantarum KSFY06 and geniposide counteract montmorillonite-induced constipation in Kunming mice.Food Sci Nutr. 2020 Sep;8(9):5128-5137Authors: Gan Y, Liang J, Diao W, Zhou X, Mu J, Pang L, Tan F, Zhao XAbstract Constipation is a common clinical manifestation of digestive system disorders and occurs worldwide. This study investigated the ability of Lactobacillus…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:58

Impact of prebiotics on immune response: from the bench to the clinic.
Impact of prebiotics on immune response: from the bench to the clinic.: Impact of prebiotics on immune response: from the bench to the clinic.Immunol Cell Biol. 2020 Sep 30;:Authors: Pujari R, Banerjee GAbstract Several preclinical and clinical studies have shown the immuno-modulatory role exerted by prebiotics in regulating immune response. In this review, we describe the mechanistic and clinical studies that decipher the cell signalling pathways implicated in the process. The prebiotic…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:58

Weissella cibaria CMU exerts an anti‑inflammatory effect by inhibiting Aggregatibacter actinomycetemcomitans‑induced NF‑κB activation in macrophages.
Weissella cibaria CMU exerts an anti‑inflammatory effect by inhibiting Aggregatibacter actinomycetemcomitans‑induced NF‑κB activation in macrophages.: Weissella cibaria CMU exerts an anti‑inflammatory effect by inhibiting Aggregatibacter actinomycetemcomitans‑induced NF‑κB activation in macrophages.Mol Med Rep. 2020 Nov;22(5):4143-4150Authors: Kim MJ, You YO, Kang JY, Kim HJ, Kang MSAbstract Periodontitis is a chronic inflammatory disease caused by various periodontal pathogens. Weissella…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:57

Lactiplantibacillus plantarum WJL administration during pregnancy and lactation improves lipid profile, insulin sensitivity and gut microbiota diversity in dyslipidemic dams and protects male offspring against cardiovascular dysfunction in later life.
Lactiplantibacillus plantarum WJL administration during pregnancy and lactation improves lipid profile, insulin sensitivity and gut microbiota diversity in dyslipidemic dams and protects male offspring against cardiovascular dysfunction in later life.: Lactiplantibacillus plantarum WJL administration during pregnancy and lactation improves lipid profile, insulin sensitivity and gut microbiota diversity in dyslipidemic dams and protects male offspring against cardiovascular dysfunction in later life.Food…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:57

Significant elevation of salivary human neutrophil peptides 1-3 levels by probiotic milk in preschool children with severe early childhood caries: a randomized controlled trial.
Significant elevation of salivary human neutrophil peptides 1-3 levels by probiotic milk in preschool children with severe early childhood caries: a randomized controlled trial.: Significant elevation of salivary human neutrophil peptides 1-3 levels by probiotic milk in preschool children with severe early childhood caries: a randomized controlled trial.Clin Oral Investig. 2020 Oct 01;:Authors: Wattanarat O, Nirunsittirat A, Piwat S, Manmontri C, Teanpaisan R, Pahumunto N, Makeudom A, Sastraruji…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:57

Periodontal pathogens promote cancer aggressivity via TLR/MyD88 triggered activation of Integrin/FAK signaling that is therapeutically reversible by a probiotic bacteriocin.
Periodontal pathogens promote cancer aggressivity via TLR/MyD88 triggered activation of Integrin/FAK signaling that is therapeutically reversible by a probiotic bacteriocin.: Periodontal pathogens promote cancer aggressivity via TLR/MyD88 triggered activation of Integrin/FAK signaling that is therapeutically reversible by a probiotic bacteriocin.PLoS Pathog. 2020 Oct;16(10):e1008881Authors: Kamarajan P, Ateia I, Shin JM, Fenno JC, Le C, Zhan L, Chang A, Darveau R, Kapila YLAbstract Epidemiological…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:56

Development of probiotic orodispersible tablets using mucoadhesive polymers for buccal mucoadhesion.
Development of probiotic orodispersible tablets using mucoadhesive polymers for buccal mucoadhesion.: Development of probiotic orodispersible tablets using mucoadhesive polymers for buccal mucoadhesion.Drug Dev Ind Pharm. 2020 Oct 02;:1-33Authors: Hoffmann A, Fischer JT, Daniels RAbstract OBJECTIVE: Probiotic bacteria, such as different lactobacilli strains, have successfully been used to treat gingivitis and periodontitis or caries. By formulating probiotics as orodispersible tablet (ODT),…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:56

Development of probiotic orodispersible tablets using mucoadhesive polymers for buccal mucoadhesion.
Development of probiotic orodispersible tablets using mucoadhesive polymers for buccal mucoadhesion.: Development of probiotic orodispersible tablets using mucoadhesive polymers for buccal mucoadhesion.Drug Dev Ind Pharm. 2020 Oct 02;:1-33Authors: Hoffmann A, Fischer JT, Daniels RAbstract OBJECTIVE: Probiotic bacteria, such as different lactobacilli strains, have successfully been used to treat gingivitis and periodontitis or caries. By formulating probiotics as orodispersible tablet (ODT),…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:55

Lactobacillus paracasei KBL382 administration attenuates atopic dermatitis by modulating immune response and gut microbiota.
Lactobacillus paracasei KBL382 administration attenuates atopic dermatitis by modulating immune response and gut microbiota.: Lactobacillus paracasei KBL382 administration attenuates atopic dermatitis by modulating immune response and gut microbiota.Gut Microbes. 2020 Nov 09;12(1):1-14Authors: Kim WK, Jang YJ, Han DH, Jeon K, Lee C, Han HS, Ko GAbstract Administration of probiotics has been linked to immune regulation and changes in gut microbiota composition, with effects on atopic dermatitis…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:54

Synbiotic Effects of Enzyme and Probiotics on Intestinal Health and Growth of Newly Weaned Pigs Challenged With Enterotoxigenic F18+ Escherichia coli.
Synbiotic Effects of Enzyme and Probiotics on Intestinal Health and Growth of Newly Weaned Pigs Challenged With Enterotoxigenic F18+ Escherichia coli.: Synbiotic Effects of Enzyme and Probiotics on Intestinal Health and Growth of Newly Weaned Pigs Challenged With Enterotoxigenic F18+ Escherichia coli.Front Vet Sci. 2020;7:573Authors: Duarte ME, Tyus J, Kim SWAbstract This study aimed to investigate the effect of dietary supplementation with xylanase and probiotics on growth performance…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:54

Efficacy of Spore Forming Bacilli Supplementation in Patients with Mild to Moderate Elevation of Triglycerides: A 12 week, Randomized, Double-Blind, Placebo Controlled Trial.
Efficacy of Spore Forming Bacilli Supplementation in Patients with Mild to Moderate Elevation of Triglycerides: A 12 week, Randomized, Double-Blind, Placebo Controlled Trial.: Efficacy of Spore Forming Bacilli Supplementation in Patients with Mild to Moderate Elevation of Triglycerides: A 12 week, Randomized, Double-Blind, Placebo Controlled Trial.Integr Med (Encinitas). 2020 Apr;19(2):22-27Authors: Campbell AW, Sinatra D, Zhang Z, Sinatra STAbstract Objective: The purpose of this randomized…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:53

Isolation and Characterization of Nitrate-Reducing Bacteria as Potential Probiotics for Oral and Systemic Health.
Isolation and Characterization of Nitrate-Reducing Bacteria as Potential Probiotics for Oral and Systemic Health.: Isolation and Characterization of Nitrate-Reducing Bacteria as Potential Probiotics for Oral and Systemic Health.Front Microbiol. 2020;11:555465Authors: Rosier BT, Moya-Gonzalvez EM, Corell-Escuin P, Mira AAbstract Recent evidence indicates that the reduction of salivary nitrate by oral bacteria can contribute to prevent oral diseases, as well as increase systemic nitric oxide…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:53

Modulation of experimental autoimmune encephalomyelitis through colonisation of the gut with Escherichia coli.
Modulation of experimental autoimmune encephalomyelitis through colonisation of the gut with Escherichia coli.: Modulation of experimental autoimmune encephalomyelitis through colonisation of the gut with Escherichia coli.Benef Microbes. 2020 Oct 13;:1-16Authors: Libbey JE, Sanchez JMS, Fleming BA, Doty DJ, DePaula-Silva AB, Mulvey MA, Fujinami RSAbstract Multiple sclerosis (MS) is a neuro-inflammatory autoimmune disease of the central nervous system (CNS) that affects young adults. It is…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:53

The potential of Streptococcus salivarius oral films in the management of dental caries: an inkjet printing approach.
The potential of Streptococcus salivarius oral films in the management of dental caries: an inkjet printing approach.: The potential of Streptococcus salivarius oral films in the management of dental caries: an inkjet printing approach.Int J Pharm. 2020 Oct 10;:119962Authors: Dodoo CC, Stapleton P, Basit AW, Gaisford SAbstract The use of probiotics, which can be administered in oro-dispersible films (ODFs) and have prolonged activity in the mouth was explored. ODFs made of xylitol and containing…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:52

MRI characterization of focal liver lesions in non-cirrhotic patients
MRI characterization of focal liver lesions in non-cirrhotic patients: assessment of added value of gadoxetic acid-enhanced hepatobiliary phase imaging: AbstractBackgroundTo evaluate the added value of the hepatobiliary (HPB) phase in gadoxetic acid-enhanced magnetic resonance imaging (MRI) in characterizing newly discovered indeterminate focal liver lesions in non-cirrhotic patients. ResultsOne-hundred and twenty-five non-cirrhotic patients (median age, 46 years; range, 20–85…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:52

False-negative focused abdominal sonography for trauma (FAST) result in patients with confirmed traumatic abdominal injury
Predictive value of a false-negative focused abdominal sonography for trauma (FAST) result in patients with confirmed traumatic abdominal injury: AbstractObjectiveTo investigate if patients with confirmed traumatic abdominal injury and a false-negative focused abdominal sonography for trauma (FAST) examination have a more favorable prognosis than those with a true-positive FAST. MethodsThis study included 97 consecutive patients with confirmed traumatic abdominal injury (based…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:51

Do we still need breast cancer screening in the era of targeted therapies and precision medicine?
Do we still need breast cancer screening in the era of targeted therapies and precision medicine?: AbstractBreast cancer (BC) is the most common female cancer and the second cause of death among women worldwide. The 5-year relative survival rate recently improved up to 90% due to increased population coverage and women’s attendance to organised mammography screening as well as to advances in therapies, especially systemic treatments. Screening attendance is associated with a mortality reduction of…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:51

Multimodality imaging features of desmoid tumors: intra-abdominal, extra-abdominal, and within the abdominal wall lesions
Multimodality imaging features of desmoid tumors: a head-to-toe spectrum: AbstractDesmoid tumors (DTs) are a rare and biologically heterogeneous group of locally aggressive fibroblastic neoplasm: their biological behavior spectrum ranges from indolent to aggressive tumors. DTs are classified as intra-abdominal, extra-abdominal, and within the abdominal wall lesions.It is well known that abdominal and extra-abdominal DTs are associated with familial adenomatous polyposis (FAP) and Gardner syndrome….

Head and Neck Medicine by Alexandros G.Sfakianakis

08:50

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Ultrasonography in the assessment of anterior knee pain
Diagnostic accuracy of ultrasonography in the assessment of anterior knee pain: AbstractBackgroundAnterior knee pain (AKP) is a problematic complaint, considered to be the most frequent cause of orthopedic consultancy for knee problems. This study aimed to highlight diagnostic accuracy of ultrasonography as a fast imaging technique in assessment of patients with AKP. Methods and resultsA prospective study was conducted on 143 patients with clinically confirmed AKP. All patients…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:49

Sports-related lower limb muscle injuries
Sports-related lower limb muscle injuries: pattern recognition approach and MRI review: AbstractMuscle injuries of the lower limbs are currently the most common sport-related injuries, the impact of which is particularly significant in elite athletes. MRI is the imaging modality of choice in assessing acute muscle injuries and radiologists play a key role in the current scenario of multidisciplinary health care teams involved in the care of elite athletes with muscle injuries. Despite the frequency…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:49

Esophageal emergencies: another important cause of acute chest pain
Esophageal emergencies: another important cause of acute chest pain: AbstractA variety of esophageal pathologies can present emergently with a chief complaint of acute chest pain. Computed tomography (CT) is often the first line of imaging in esophageal emergencies and provides useful information—even without an initial suspicion—when used in conjunction with other imaging modalities such as esophagography and direct visualization. We review various urgent and emergent esophageal disease entities…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:48

Serum cystatin C: A potential predictor for hospital-acquired acute kidney injury in patients with acute exacerbation of COPD
Serum cystatin C: A potential predictor for hospital-acquired acute kidney injury in patients with acute exacerbation of COPD: Chronic Respiratory Disease, Volume 17, Issue , January-December 2020. Hospital-acquired acute kidney injury (HA-AKI) is associated with poor prognosis. In this study, we evaluated whether serum cystatin C on admission could predict AKI in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). The retrospective study was conducted using data on…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:46

Idiopathic Subglottic Stenosis
Idiopathic Subglottic Stenosis: An Institutional Review of Outcomes With a Multimodality Surgical Approach.: Idiopathic Subglottic Stenosis: An Institutional Review of Outcomes With a Multimodality Surgical Approach.Otolaryngol Head Neck Surg. 2020 Oct 13;:194599820966978Authors: Dwyer CD, Qiabi M, Fortin D, Inculet RI, Nichols AC, MacNeil SD, Malthaner R, Yoo J, Fung KAbstract OBJECTIVES: This article reports on a unique cohort of patients with idiopathic subglottic stenosis spilt fairly…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:39

Encorafenib-metastatic colorectal cancers with BRAF V600E mutation after systemic chemotherapy].
[New drug approval: Encorafenib-metastatic colorectal cancers with BRAF V600E mutation after systemic chemotherapy].: [New drug approval: Encorafenib-metastatic colorectal cancers with BRAF V600E mutation after systemic chemotherapy].Bull Cancer. 2020 Oct 09;:Authors: Boilève A, Samalin EPMID: 33046237 [PubMed – as supplied by publisher]

Head and Neck Medicine by Alexandros G.Sfakianakis

08:38

Breast Cancer Screening with Digital Breast Tomosynthesis in Combination with Synthetic versus Digital Mammography.
Multicenter Evaluation of Breast Cancer Screening with Digital Breast Tomosynthesis in Combination with Synthetic versus Digital Mammography.: Multicenter Evaluation of Breast Cancer Screening with Digital Breast Tomosynthesis in Combination with Synthetic versus Digital Mammography.Radiology. 2020 Oct 13;:200240Authors: Zuckerman SP, Sprague BL, Weaver DL, Herschorn SD, Conant EFAbstract BackgroundDigital breast tomosynthesis (DBT) combined with digital mammography (DM) is increasingly…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:38

MRI of Skeletal Muscles in Participants with Type 2 Diabetes with or without Diabetic Polyneuropathy.
MRI of Skeletal Muscles in Participants with Type 2 Diabetes with or without Diabetic Polyneuropathy.: MRI of Skeletal Muscles in Participants with Type 2 Diabetes with or without Diabetic Polyneuropathy.Radiology. 2020 Oct 13;:192647Authors: Stouge A, Khan KS, Kristensen AG, Tankisi H, Schlaffke L, Froeling M, Væggemose M, Andersen HAbstract BackgroundDiabetic polyneuropathy (DPN) is associated with loss of muscle strength. MRI including diffusion-tensor imaging (DTI) may enable detection…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:37

Arterial Spin Labeling MRI in Carotid Stenosis: Arterial Transit Artifacts May Predict Symptoms.
Arterial Spin Labeling MRI in Carotid Stenosis: Arterial Transit Artifacts May Predict Symptoms.: Arterial Spin Labeling MRI in Carotid Stenosis: Arterial Transit Artifacts May Predict Symptoms.Radiology. 2020 Oct 13;:200225Authors: Di Napoli A, Cheng SF, Gregson J, Atkinson D, Markus JE, Richards T, Brown MM, Sokolska M, Jäger HRAbstract BackgroundStenosis of the internal carotid artery has a higher risk for stroke. Many investigations have focused on structure and plaque composition as…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:37

Nonablative Fractional Lasers (NAFL) on Hypertrophic Scars
Early Treatment Effects of Nonablative Fractional Lasers (NAFL) on Hypertrophic Scars in an Animal Model: Background and ObjectivesRecently, there have been several attempts to apply the laser therapy to hypertrophic scars (HTS). In particular, the fractional laser is in the spotlight for its usefulness in rapid wound healing and dermal remodeling. However, most previous studies have focused on the ablative fractional laser (AFL), and there are no studies on the mechanism of the nonablative fractional…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:36

Circular RNA hsa_circ_0003204 promotes cervical cancer cell proliferation, migration, and invasion by regulating MAPK pathway.
Circular RNA hsa_circ_0003204 promotes cervical cancer cell proliferation, migration, and invasion by regulating MAPK pathway.: Circular RNA hsa_circ_0003204 promotes cervical cancer cell proliferation, migration, and invasion by regulating MAPK pathway.Cancer Biol Ther. 2020 Oct 13;:1-11Authors: Huang XB, Song KJ, Chen GB, Liu R, Jiang ZF, He YLAbstract Cervical cancer (CC) is the second most common malignancy in women worldwide. The mechanism underlying CC development remains unclear….

Head and Neck Medicine by Alexandros G.Sfakianakis

08:35

Apatinib and Camrelizumab in Recurrent or Metastatic Nasopharyngeal Carcinoma With First-line Treatment Failure
Apatinib and Camrelizumab in Recurrent or Metastatic Nasopharyngeal Carcinoma With First-line Treatment Failure: Conditions: Nasopharyngeal Carcinoma; Recurrent Nasopharyngeal Carcinoma; Metastatic Nasopharyngeal Carcinoma; Chemotherapy Effect; Immunotherapy; Molecular Targeted TherapyIntervention: Drug: Apatinib plus CamrelizumabSponsor: Sun Yat-sen UniversityRecruiting

Head and Neck Medicine by Alexandros G.Sfakianakis

08:35

Programmed Cell Death 2-like (Pdcd2l) Is Required for Embryonic Development
Programmed Cell Death 2-like (Pdcd2l) Is Required for Mouse Embryonic Development: Globozoospermia is a rare form of male infertility where men produce round-headed sperm that are incapable of fertilizing an oocyte naturally. In a previous study where we undertook a whole exome screen to define novel genetic causes of globozoospermia, we identified homozygous mutations in the gene PDCD2L. Two brothers carried a p.(Leu225Val) variant predicted to introduce a novel splice donor site, thus presenting…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:34

Vorinostat Plus Sirolimus or Everolimus in Patients with Relapsed Refractory Hodgkin Lymphoma
Safety and Efficacy of Vorinostat Plus Sirolimus or Everolimus in Patients with Relapsed Refractory Hodgkin Lymphoma: Purpose:Preclinical and early clinical data suggested that combining histone deacetylase (HDAC) and mTOR inhibitors can synergistically inhibit Hodgkin lymphoma.Patients and Methods:During the dose-escalation study (ClinicalTrials.gov number: NCT01087554) with the HDAC inhibitor vorinostat and the mTOR inhibitor sirolimus (V+S), a patient with Hodgkin lymphoma refractory to nine prior…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:34

Tucatinib for the Treatment of Patients with Advanced or Metastatic HER2-Positive Breast Cancer
FDA Approval Summary: Tucatinib for the Treatment of Patients with Advanced or Metastatic HER2-Positive Breast Cancer: On April 17, 2020, the FDA approved tucatinib in combination with trastuzumab and capecitabine for the treatment of patients with advanced unresectable or metastatic HER2-positive breast cancer, including patients with brain metastases, who have received one or more prior anti-HER2-based regimens in the metastatic setting. This was the first new molecular entity evaluated under Project…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:33

Bioinformatics tools for identification of long noncoding RNAs
A systematic evaluation of bioinformatics tools for identification of long noncoding RNAs [Article]: High-throughput RNA sequencing unveiled the complexity of transcriptome and significantly increased the records of long noncoding RNAs (lncRNAs) which were reported to participate in a variety of biological processes. Identification of lncRNAs is a key step of lncRNA analysis, and a bunch of bioinformatics tools have been developed for this purpose in recent years. While these tools allow us to identify…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:33

Circular RNA hsa_circ_0003204 promotes cervical cancer cell proliferation, migration, and invasion by regulating MAPK pathway.
Circular RNA hsa_circ_0003204 promotes cervical cancer cell proliferation, migration, and invasion by regulating MAPK pathway.: Circular RNA hsa_circ_0003204 promotes cervical cancer cell proliferation, migration, and invasion by regulating MAPK pathway.Cancer Biol Ther. 2020 Oct 13;:1-11Authors: Huang XB, Song KJ, Chen GB, Liu R, Jiang ZF, He YLAbstract Cervical cancer (CC) is the second most common malignancy in women worldwide. The mechanism underlying CC development remains unclear….

Head and Neck Medicine by Alexandros G.Sfakianakis

08:32

Dry Eye Disease Among Patients Using Continuous Positive Airway Pressure or Other Nasal Mask Therapy Devices to Treat Sleep Apnea
The Prevalence and Incidence of Dry Eye Disease Among Patients Using Continuous Positive Airway Pressure or Other Nasal Mask Therapy Devices to Treat Sleep Apnea: Authors Matossian C, Song X, Chopra I, Sainski-Nguyen A, Ogundele AReceived 1 August 2020Accepted for publication 17 September 2020Published 15 October 2020 Volume 2020:14 Pages 3371—3379DOI https://doi.org/10.2147/OPTH.S274949Checked for plagiarism YesReview by Single anonymous peer reviewPeer reviewer comments 3Editor who approved publication:…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:32

iStent Trabecular Micro-Bypass Stent Implantation with Cataract Surgery
iStent Trabecular Micro-Bypass Stent Implantation with Cataract Surgery in a Japanese Glaucoma Population: Authors Nitta K, Yamada Y, Morokado S, Sugiyama KReceived 28 July 2020Accepted for publication 28 September 2020Published 15 October 2020 Volume 2020:14 Pages 3381—3391DOI https://doi.org/10.2147/OPTH.S274281Checked for plagiarism YesReview by Single anonymous peer reviewPeer reviewer comments 5Editor who approved publication: Dr Scott FraserKoji Nitta,1 Yutaro Yamada,1 Satomi Morokado,1 Kazuhisa…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:31

Optical Coherence Tomography Angiography Features of Neovascularization in Proliferative Diabetic Retinopathy
Optical Coherence Tomography Angiography Features of Neovascularization in Proliferative Diabetic Retinopathy: Sara Vaz-Pereira,1,2,* João Jesus Silva,2,* K Bailey Freund,3– 5 Michael Engelbert3– 51Department of Ophthalmology, Centro Hospitalar Universitário de Lisboa Norte, EPE – Hospital de Santa Maria, Lisbon, Portugal; 2Department of Ophthalmology, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal; 3Vitreous Retina Macula Consultants of New York, New York, NY, USA; 4LuEsther T….

Head and Neck Medicine by Alexandros G.Sfakianakis

08:30

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Novel selective agonist of GPR18, PSB‐KK‐1415 exerts potent anti‐inflammatory and anti‐nociceptive activities in animal models of intestinal inflammation and inflammatory pain
Novel selective agonist of GPR18, PSB‐KK‐1415 exerts potent anti‐inflammatory and anti‐nociceptive activities in animal models of intestinal inflammation and inflammatory pain: A recently deorphanized receptor, GPR18 showed to act with several endogenous cannaboinoid ligands. Among several potent functionalities the receptor activation also leads to the induction of anti‐infammatory and antinociceptive action. By using highly selective agonist of GPR18, PSB‐KK‐1415 we achieved an inflammation alleviation…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:29

Erdheim-Chester Disease (ECD) by 18F-FDG PET/CT
18 F-FDG PET/CT versus anatomic imaging for evaluating disease extent and clinical trial eligibility in Erdheim-Chester disease: results from 50 patients in a registry study: AbstractObjectivesThe aim of this study was to [1] characterize distribution of Erdheim-Chester Disease (ECD) by 18F-FDG PET/CT and [2] determine the utility of metabolic (18F-FDG PET/CT) imaging versus anatomic imaging (CT or MRI) in evaluating ECD patients for clinical trial eligibility. Methods18F-FDG…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:28

Improved cancer detection in Waldeyer’s tonsillar ring by 68 Ga-FAPI PET/CT imaging
Improved cancer detection in Waldeyer’s tonsillar ring by 68 Ga-FAPI PET/CT imaging: AbstractPurposeIn cancer of unknown primary (CUP), positron emission tomography/computed tomography (PET/CT) with the glucose analog [18F]FDG represents the standard imaging approach for localization of the malignant primary. Frequently, however, [18F]FDG PET/CT cannot precisely distinguish between small occult tumors and chronic inflammation, especially in Waldeyer’s tonsillar ring. To improve the accuracy for detecting…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:26

Cetacean vertebral trabecular bone
Microarchitecture of cetacean vertebral trabecular bone among swimming modes and diving behaviors: Cetacean vertebral trabecular bone volume fraction was greatest in rigid‐torso shallow divers, smallest in flexible‐torso deep divers, and intermediate in rigid‐torso deep divers. Degree of anisotropy was greater in rigid‐torso swimmers compared to their flexible‐torso counterparts. Despite having osteoporotic skeletons overall, cetacean vertebrae show greater bone volume fraction, trabecular thickness,…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:25

Loss of 5-Hydroxymethylcytosine is an Epigenetic Hallmark of Thyroid Carcinomas with TERT Promoter Mutations
Loss of 5-Hydroxymethylcytosine is an Epigenetic Hallmark of Thyroid Carcinomas with TERT Promoter Mutations: AbstractEpigenetic dysregulation is a hallmark of cancer, and aberrant methylation of cytosine residues plays a crucial role in abnormal gene expression in cancer cells. Recent studies demonstrate that 5-hydroxymethylcytosine (5-hmC) generated through 5-methylcytosine (5-mC) oxidation is significantly depleted in various cancers. However, whether 5-hmC levels change during the stepwise progression…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:25

pCLIF-SOFA is a reliable outcome prognostication score of critically ill children with cirrhosis: an ESPNIC multicentre study
pCLIF-SOFA is a reliable outcome prognostication score of critically ill children with cirrhosis: an ESPNIC multicentre study: Data on outcome of critically ill children with cirrhosis are scarce. We aimed to evaluate the prognostic accuracy of sequential organs scoring systems in children with cirrhosis admitted to Paediatric Intensi…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:24

High doses of tigecycline
High doses of tigecycline are associated with satisfactory plasmatic and pulmonary concentrations for the treatment of severe infections due to fully susceptible bacteria: do we need even higher doses in patients under CRRT?:

Head and Neck Medicine by Alexandros G.Sfakianakis

08:24

Tigecycline pharmacokinetics in critically ill patients on renal replacement therapy
Tigecycline pharmacokinetics in critically ill patients on renal replacement therapy: possible warnings and potential perspectives for the research agenda:

Head and Neck Medicine by Alexandros G.Sfakianakis

08:23

Persistent swallowing disorders after extubation
Persistent swallowing disorders after extubation in mechanically ventilated patients in ICU: a two-center prospective study: Persistent swallowing disorders (SD) are non-pulmonary complications of mechanical ventilation (MV). However, there are few clinical studies on persistent SD in critically ill patients undergoing tracheal intu…

Head and Neck Medicine by Alexandros G.Sfakianakis

08:23

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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia,

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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Patient-Specific Hemodynamics of New Coronary Artery Bypass Configurations
Patient-Specific Hemodynamics of New Coronary Artery Bypass Configurations: AbstractPurposeThis study aims to quantify the patient-specific hemodynamics of complex conduit routing configurations of coronary artery bypass grafting (CABG) operation which are specifically suitable for off-pump surgeries. Coronary perfusion efficacy and local hemodynamics of multiple left internal mammary artery (LIMA) with sequential and end-to-side anastomosis are investigated. Using a full anatomical model comprised…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:17

Correlation of liver-to-spleen ratio, lung CT scores, clinical, and laboratory findings of COVID-19 patients with two consecutive CT scans
Correlation of liver-to-spleen ratio, lung CT scores, clinical, and laboratory findings of COVID-19 patients with two consecutive CT scans: AbstractPurposeGiven the lack of information about abdominal imaging findings and correlation with clinical features of COVID-19, we aimed to evaluate the changes in hepatic attenuation during the course of disease. Our aim was to correlate the liver-to-spleen ratio (L/S), clinical, laboratory findings, and lung CT scores of patients with COVID-19 who had two…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:17

WNT3 and LEF1 as markers for diagnosis and survival prediction in chronic lymphocytic leukemia patients
WNT3 and LEF1 as markers for diagnosis and survival prediction in chronic lymphocytic leukemia patients: SummaryBackgroundThe Wnt pathway is aberrantly activated in chronic lymphocytic leukemia (CLL) and contributes to the antiapoptotic and mitogenic characteristics of CLL cells. Lymphoid enhancer-binding factor‑1 (LEF1) acts as a mediator and key transcription factor of the Wnt/β-catenin pathway. LEF1 helps to regulate important genes involved in tumor cell death mechanisms. …

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:16

Co-treatment with endoscopic laryngopharyngeal surgery and endoscopic submucosal dissection
Co-treatment with endoscopic laryngopharyngeal surgery and endoscopic submucosal dissection: Endoscopic laryngopharyngeal surgery (ELPS) is an effective and minimally invasive treatment for pharyngeal cancers. However, the disadvantages of ELPS are the interference of instruments in the operative field and the difficulty in approaching certain areas. To overcome these drawbacks, we began to perform combination treatment of ELPS and endoscopic submucosal dissection (ESD). The aim of the present study…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:16

Augmentation of the posterior pharyngeal wall with autologous tragal cartilage for management of velopharyngeal valve insufficiency in adults
Augmentation of the posterior pharyngeal wall with autologous tragal cartilage for management of velopharyngeal valve insufficiency in adults: The study aims to evaluate posterior pharyngeal wall augmentation using autologous tragal cartilage graft in adults with velopharyngeal valve insufficiency (VPI).

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:15

Chronic epipharyngitis
Outcome of an outpatient specialty clinic for chronic epipharyngitis: In Japan, chronic epipharyngitis became a subject of interest in the 1960s and is currently garnering renewed attention. Previous studies have focused only on the similarities between the immunological characteristics of the tonsil and epipharynx and reported the efficacy of epipharyngeal abrasive therapy (EAT) in patients with IgA nephropathy. However, endoscopic findings of chronic epipharyngitis have not yet been fully evaluated,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:15

Polyglycolic acid (PGA) sheets and fibrin glue in preventing laryngopharyngeal bleeding
Efficacy of polyglycolic acid sheets and fibrin glue for the prevention of post-ELPS bleeding: To assess the efficacy and safety of a covering method using polyglycolic acid (PGA) sheets and fibrin glue in preventing laryngopharyngeal bleeding after endoscopic laryngopharyngeal surgery (ELPS) combined with endoscopic submucosal dissection (ESD).

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:12

Tocilizumab for treating COVID-19
Tocilizumab for treating COVID-19: a systemic review and meta-analysis of retrospective studies: AbstractObjectivesCOVID-19 has become a global epidemic, and effective therapies have not been discovered up to now. We conducted this study to explore the effectiveness and safety of tocilizumab recently used for treating COVID-19. MethodA comprehensive search was conducted (up to September 27, 2020), and 19 eligible records were identified according to the inclusion and exclusion…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:11

The association of GATM polymorphism with statin-induced myopathy
The association of GATM polymorphism with statin-induced myopathy: a systematic review and meta-analysis: AbstractPurposeStatin-induced myopathy (SIM) is the commonest reason for discontinuation of statin therapy. The aim of this present meta-analysis is to assess the relationship between glycine amidinotransferase gene (GATM) polymorphism and risk of SIM. MethodsMEDLINE, EMBASE, Web of Science, and Cochrane Library databases were searched systematically for case-control studies…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:11

Intra-osseous basivertebral nerve radiofrequency ablation (BVA) for the treatment of vertebrogenic chronic low back pain
Intra-osseous basivertebral nerve radiofrequency ablation (BVA) for the treatment of vertebrogenic chronic low back pain: AbstractStudy designProspective experimental uncontrolled trial. BackgroundVertebrogenic pain is a frequently underestimated cause of chronic low back pain (LBP). Vertebral endplate degeneration, characterized by cortical bone damage and subchondral bone inflammatory reaction, is a significant source of LBP, the responsible of the pain transmission being the…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:10

mTICCS and its inter-rater reliability to predict the need for massive transfusion in severely injured patients
mTICCS and its inter-rater reliability to predict the need for massive transfusion in severely injured patients: AbstractPurposeThe modified Trauma-Induced Coagulopathy Clinical Score (mTICCS) presents a new scoring system for the early detection of the need for a massive transfusion (MT). This easily applicable score was validated in a large trauma cohort and proven comparable to more established complex scoring systems. However, the inter-rater reliability of the mTICCS has not yet been investigated….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:08

Reconstructing the Central Arch Mandibular Defects
A Novel and Simple Technique of Reconstructing the Central Arch Mandibular Defects—a Solution During the Resource-Constrained Setting of COVID Crisis: AbstractThe current COVID 19 pandemic has a major impact on healthcare delivery globally. Oral cancer involving anterior arch of mandible is difficult to reconstruct and ideally, requires free fibular osteomyocutaneous flap. During this time of resource constraint situation, these free flaps are not a great choice, as it increases exposure of both…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:07

Neurovascular Complications After Neck Dissection
Neurovascular Complications After Neck Dissection: a Prospective Analysis at a Tertiary Care Centre in South India: AbstractOwing to high incidence of oral cancers in India, neck dissection is the most commonly performed procedure in any head and neck oncology setup. This surgery is particularly prone to various neurovascular complications due to intricate anatomy of neck, but the exact incidence has been studied less especially in Indian subcontinent. A prospective observational study was done on…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:06

Treatment Outcomes of Early Carcinoma Cervix Before and After Sub-specialization
Treatment Outcomes of Early Carcinoma Cervix Before and After Sub-specialization: AbstractThis study aimed to compare the treatment outcomes in carcinoma cervix before and after gynecologic oncology sub-specialization at a tertiary care hospital, in India. This was a retrospective cohort study comparing women with operable cervical cancer who underwent radical hysterectomy before and after gynecologic oncology sub-specialization. Electronic medical records of women operated for early carcinoma cervix…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:59

Pattern of Lymph Node Metastasis in Endometrial Cancer
Pattern of Lymph Node Metastasis in Endometrial Cancer: a Single Institution Experience: AbstractSurgical staging remains the standard primary treatment of endometrial cancer. Lymph node metastasis is the most important prognostic factor which helps in deciding adjuvant treatment. Extensive lymphadenectomy is associated with increased incidence of morbidity. The role of lymphadenectomy in surgical staging is still controversial especially in early stage disease. The surgico-pathological pattern of…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:59

Surgical and Oncological Outcomes in Locally Advanced Thymoma
Surgical and Oncological Outcomes in Locally Advanced Thymoma: AbstractThis study aimed at reporting the surgical management of locally advanced thymoma (Masaoka stages III and IVA) and evaluating the factors predicting the survival. This is a retrospective analysis of patients operated for locally advanced thymoma from March 2012 to December 2019 in a thoracic surgery center in India. An analysis of all perioperative variables including complications was carried out. The influence of various predictors…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:57

Who Needs Level III Lymph Node Dissection in Carcinoma Breast
Who Needs Level III Lymph Node Dissection in Carcinoma Breast—Study from a Tertiary Care Center: AbstractIn Indian females, breast cancer is the most common cancer with a late stage of presentation leading to one-third of patients undergoing modified radical mastectomy (MRM). Our study is undertaken to find out predictors of level III axillary lymph node metastasis in breast cancer and who needs complete axillary lymph node dissection (ALND). Retrospective study of 146 patients who undergone MRM…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:57

Validation of Sentinel Lymph Node Biopsy Technique Using Dual Tracer Technique in Post Lumpectomy Early Breast Cancer Patients
Validation of Sentinel Lymph Node Biopsy Technique Using Dual Tracer Technique in Post Lumpectomy Early Breast Cancer Patients: AbstractSentinel lymph node biopsy (SLNB) is the gold standard for the evaluation of axilla in clinically node-negative early breast cancers. There is limited data on the role and efficacy of the same in the post lumpectomy scenario. This prospective interventional study was conducted over 1 year on 30 post lumpectomy pT1/2 cN0 patients. SLNB was performed by preoperative…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:57

Osteosarcoma with Tongue Metastasis
Osteosarcoma with Tongue Metastasis: a Rare Case Report:

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:56

pectoralis major myocutaneous (PMMC) flap as bilobed flaps…..Bilobed PMMC in Females: Our Challenging yet Meritorious Experience
Bilobed PMMC in Females: Our Challenging yet Meritorious Experience: AbstractThe gold standard reconstructive options for full-thickness defect of the oral cavity after resection of malignant lesions are the free flaps. But in developing nations due to resource constraints, it cannot be offered to all. Hence, pectoralis major myocutaneous (PMMC) flap as bilobed flaps is most commonly used. Bilobed flaps are technically demanding, and in females, it is more challenging due to higher complication rates…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:56

Low Cost, Low Dose, Oral, Neoadjuvant Chemotherapy Protocol in Locally Advanced Borderline Oral Cancers—Feasibility Study
Low Cost, Low Dose, Oral, Neoadjuvant Chemotherapy Protocol in Locally Advanced Borderline Oral Cancers—Feasibility Study: AbstractA vast majority of oral cancer patients in developing countries present in an advanced stage with borderline resectable/inoperable stage to busy resource-constrained tertiary cancer centers. Conventional chemotherapy protocols are associated with issues like toxicity, tolerance, cost, and compliance. The present study was conducted to assess the feasibility of low-cost…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:55

��-Catenin—a Possible Prognostic Molecular Marker for Recurrence in Histopathologically Negative Surgical Margin of Oral Cancer
��-Catenin—a Possible Prognostic Molecular Marker for Recurrence in Histopathologically Negative Surgical Margin of Oral Cancer: AbstractThe locoregional recurrence in oral cancer is not predicted by the histopathological parameters solely as the normal morphological looking cells harbor the genomic instability which acts as the potential tumor cells for recurrence in future. Therefore, there is an urgent need of the biomarker for prognostic stratification of patients with high risk of disease recurrence…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:55

Malignant Peripheral Nerve Sheath Tumour of Cervix
A Case Series on Malignant Peripheral Nerve Sheath Tumour of Cervix: an Institutional Report:

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:55

Coexistence of Carcinoma and Tuberculosis of Colon
A Retrospective Cohort Study of Coexistence of Carcinoma and Tuberculosis of Colon: 12-Year Experience: AbstractCoexistence of carcinoma colon and tuberculosis is rare. The aim of this study is to present our 12-year experience on colonic carcinoma with coexisting colonic TB. Histopathology and imaging records of 189 patients of colonic carcinoma patients who underwent treatment in surgical unit 6 in our institute between January 2006 and December 2017 were reviewed. In 7 patients, histopathology…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:54

Georg von Békésy and Bruce Mer: Early Pioneers of Endoscopic Ear Surgery
Georg von Békésy and Bruce Mer: Early Pioneers of Endoscopic Ear Surgery: Otolaryngology–Head and Neck Surgery, Ahead of Print. The binocular operative microscope has been the workhorse of otologic and neurotologic surgeons since the 1950s. Since its advent, however, surgeons recognized that the operative microscope could not “look around corners” and its line-of-sight technology required soft tissue and bony dissection to enable light to reach the surgical plane. Endoscopic technology has evolved…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:54

Prevalence of Tinnitus in an Aging Population and Its Relation to Age and Hearing Loss
Prevalence of Tinnitus in an Aging Population and Its Relation to Age and Hearing Loss: Otolaryngology–Head and Neck Surgery, Ahead of Print. ObjectivesTinnitus is a common hearing-related disorder, which may have a large impact on daily life. With aging populations worldwide, it is important to gain insight in the occurrence of tinnitus at older ages and to understand its relationship with age-related hearing loss. We investigated the prevalence of tinnitus among a general aging population, across…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:53

Pediatric Basilar Skull Fracture Mechanisms
Pediatric Basilar Skull Fracture Mechanisms and Trends From 2007 to 2018: Otolaryngology–Head and Neck Surgery, Ahead of Print. ObjectivesTo evaluate the specific mechanism and trend of injury resulting in pediatric basilar skull fractures.Study DesignRetrospective chart review of a trauma database.SettingTertiary care children’s hospital.MethodsPatients ≤18 years old with basilar skull fractures were identified via the trauma database for admissions from 2007 to 2018. Patients were identified with…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:53

Pectoralis Major Onlay vs Interpositional Reconstruction Fistulation After Salvage Total Laryngectomy
Pectoralis Major Onlay vs Interpositional Reconstruction Fistulation After Salvage Total Laryngectomy: Systematic Review and Meta-analysis: Otolaryngology–Head and Neck Surgery, Ahead of Print. ObjectiveTo evaluate the difference in pharygocutaneous fistula (PCF) development between pectoralis major flap onlay and interpositional reconstructions after salvage total laryngectomy (STL).Data SourcesMedline, Cochrane, Embase, Web of Science, CINAHL, and ClinicalTrials.gov.Review MethodsA systematic review…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:52

Biomarkers for Malignant Potential in Vocal Fold Leukoplakia
Biomarkers for Malignant Potential in Vocal Fold Leukoplakia: A State of the Art Review: Otolaryngology–Head and Neck Surgery, Ahead of Print. ObjectiveTo explore biomarkers that are candidates for understanding potential degeneration to malignancy of vocal fold leukoplakia (VFL), with the goal of guiding future diagnostic and treatment recommendations.Data SourcesPubMed and Medline search engines.Review MethodsA systematic review was conducted by searching the following key words: vocal fold or…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:52

Sialendoscopy in Chronic Obstructive Sialadenitis Without Sialolithiasis: A Prospective Cohort Study
Sialendoscopy in Chronic Obstructive Sialadenitis Without Sialolithiasis: A Prospective Cohort Study: Otolaryngology–Head and Neck Surgery, Ahead of Print. ObjectivesTo evaluate long-term chronic sialadenitis symptoms in patients without sialolithiasis following sialendoscopy-assisted salivary duct surgery (SASDS) compared to a control group managed conservatively.Study DesignProspective cohort study.SettingTertiary care center.MethodsThirty-six patients (52 glands) with chronic sialadenitis without…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:52

Polysomnographic Outcomes After Observation for Mild Obstructive Sleep Apnea in Children Younger Than 3 Years
Polysomnographic Outcomes After Observation for Mild Obstructive Sleep Apnea in Children Younger Than 3 Years: Otolaryngology–Head and Neck Surgery, Ahead of Print. ObjectiveMild obstructive sleep apnea (OSA), particularly in young children, is often treated with observation. However, there is little evidence regarding the outcomes with this approach. Our aim was to assess the impact of observation on sleep for children aged ❤ years with mild OSA.Study DesignCase-control study.SettingPediatric…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:52

Sleep Architecture in Children With Down Syndrome With and Without Obstructive Sleep Apnea
Sleep Architecture in Children With Down Syndrome With and Without Obstructive Sleep Apnea: Otolaryngology–Head and Neck Surgery, Ahead of Print. ObjectiveTo characterize polysomnographic sleep architecture in children with Down syndrome and compare findings in those with and without obstructive sleep apnea.Study DesignCase series with retrospective review.SettingSingle tertiary pediatric hospital (2005-2018).MethodsWe reviewed the electronic health records of patients undergoing polysomnography…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:51

Temporal Bone Models
Multi-institutional Comparison of Temporal Bone Models: A Collaboration of the AAO-HNSF 3D-Printed Temporal Bone Working Group: Otolaryngology–Head and Neck Surgery, Ahead of Print. ObjectiveThe American Academy of Otolaryngology–Head and Neck Surgery Foundation’s (AAO-HNSF’s) 3D-Printed Temporal Bone Working Group was formed with the goal of sharing information and experience relating to the development of 3D-printed temporal bone models. The group conducted a multi-institutional study to directly…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:51

Radiologic Findings Associated With Pediatric Congenital Idiopathic Bilateral Vocal Fold Dysfunction
Multi-institutional Evaluation of Radiologic Findings Associated With Pediatric Congenital Idiopathic Bilateral Vocal Fold Dysfunction: Otolaryngology–Head and Neck Surgery, Ahead of Print. ObjectiveTo report brain magnetic resonance imaging (MRI) and ultrasonography findings in pediatric patients with congenital idiopathic bilateral vocal fold dysfunction and analyze factors associated with its etiology and resolution.Study DesignCase series with retrospective review.SettingTertiary care multi-institutional…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:51

Oral Intubation Attempts in Patients With a Laryngectomy: A Significant Safety Threat
Oral Intubation Attempts in Patients With a Laryngectomy: A Significant Safety Threat: Otolaryngology–Head and Neck Surgery, Ahead of Print. It is impossible to secure the airway of a patient with “neck-only” breathing transorally or transnasally. Surgical removal of the larynx (laryngectomy) or tracheal rerouting (tracheoesophageal diversion or laryngotracheal separation) creates anatomic discontinuity. Misguided attempts at oral intubation of neck breathers may cause hypoxic brain injury or death….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:50

Clinical Predictors of Facial Nerve Outcomes After Surgical Resection of Vestibular Schwannoma
Clinical Predictors of Facial Nerve Outcomes After Surgical Resection of Vestibular Schwannoma: Otolaryngology–Head and Neck Surgery, Ahead of Print. ObjectiveTo identify clinical predictors of facial nerve (FN) outcomes after microsurgical resection of vestibular schwannoma (VS).Study DesignProspective cohort study.SettingAcademic medical center.MethodsConsecutive patients undergoing VS resection from November 2017 to October 2019 were included. FN function was evaluated with the House-Brackmann…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:50

Clinical Radiographic Predictors of Response to Hypoglossal Nerve Stimulation for Obstructive Sleep Apnea
Clinical Radiographic Predictors of Response to Hypoglossal Nerve Stimulation for Obstructive Sleep Apnea: Otolaryngology–Head and Neck Surgery, Ahead of Print. ObjectiveTo determine if clinically acquired cephalometric measurements, specifically soft palate size, can predict hypoglossal nerve stimulation outcomes.Study DesignCombined prospective cohort study and retrospective review.SettingUS sleep otolaryngology training program.MethodsAdults with obstructive sleep apnea and apneahypopnea index…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:50

Association Between the Duration of Hearing Loss and Hearing Outcomes in Surgery for Otosclerosis
Association Between the Duration of Hearing Loss and Hearing Outcomes in Surgery for Otosclerosis: Otolaryngology–Head and Neck Surgery, Ahead of Print. IntroductionHearing loss due to otosclerosis is effectively treated with surgery. The association between duration of hearing loss and surgical outcomes is unknown.Study DesignRetrospective review.SettingLarge otology referral center.MethodsPatients undergoing primary stapes surgery for otosclerosis from 2005 to 2017 were evaluated according to their…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:50

Can Computed Tomography Findings Predict the Recurrence of Sinonasal Inverted Papilloma?
Can Computed Tomography Findings Predict the Recurrence of Sinonasal Inverted Papilloma?: Otolaryngology–Head and Neck Surgery, Ahead of Print. ObjectiveTo evaluate the correlation between the ability to predict the attachment site of sinonasal inverted papilloma by computed tomography and the long-term surgical outcome.Study DesignRetrospective cohort study.SettingFive tertiary medical centers.MethodsStudy patients underwent attachment-oriented resection of inverted papilloma. The primary outcome…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:49

Αφαίρεση διαφημίσεων

Velcro Ties in Early Postoperative Pediatric Tracheostomy Care
Velcro Ties in Early Postoperative Pediatric Tracheostomy Care: A Systematic Review and Meta-analysis: Otolaryngology–Head and Neck Surgery, Ahead of Print. ObjectiveTo systematically review the literature to determine the difference in complications between standard twill and Velcro ties following pediatric tracheostomy.Data SourcesMEDLINE, Embase, the Cochrane Database of Systematic Reviews, the Cochrane Central Register of Controlled Trials, Web of Science, and CINAHL Plus were searched up to…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:49

Self-perceived Taste and Flavor Perception
Self-perceived Taste and Flavor Perception: Associations With Quality of Life in Patients With Olfactory Loss: Otolaryngology–Head and Neck Surgery, Ahead of Print. ObjectiveTo evaluate associations between self-perceived chemosensory functions of smell, taste, and flavor perception with olfactory-specific quality of life (QoL) in patients with olfactory dysfunction (OD) and whether these associations would be influenced by other factors, such as duration or etiology of smell loss.Study DesignRetrospective…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:49

Myringoplasty With an Ultrathin Cartilage-Perichondrium Complex Graft
Myringoplasty With an Ultrathin Cartilage-Perichondrium Complex Graft Versus Temporalis Fascia Graft: A Propensity Score–Matched Analysis: Otolaryngology–Head and Neck Surgery, Ahead of Print. ObjectiveTo compare endoscopic myringoplasty using the cartilage-perichondrium complex as a graft (test group) with temporalis fascia microscopic myringoplasty (control group).Study DesignA retrospective cohort study.SettingDepartment of Otorhinolaryngology in a tertiary Chinese hospital.MethodsData were collected…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:48

Idiopathic Subglottic Stenosis
Idiopathic Subglottic Stenosis: An Institutional Review of Outcomes With a Multimodality Surgical Approach: Otolaryngology–Head and Neck Surgery, Ahead of Print. ObjectivesThis article reports on a unique cohort of patients with idiopathic subglottic stenosis spilt fairly equally between endoscopic and open surgical approaches. Patients’ sequence of operations and reinterventions over time are outlined, offering insight to improve surgical counseling and allow for informative, autonomous patient…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:48

Olfactory Cleft Measurements and Anosmia
Olfactory Cleft Measurements and COVID-19–Related Anosmia: Otolaryngology–Head and Neck Surgery, Ahead of Print. ObjectiveThis study aimed to investigate the differences in olfactory cleft (OC) morphology in coronavirus disease 2019 (COVID-19) anosmia compared to control subjects and postviral anosmia related to infection other than severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).Study DesignProspective.SettingThis study comprises 91 cases, including 24 cases with anosmia due to SARS-CoV-2,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:48

Orally Inhaled Drug Particle Transport in Computerized Models of Laryngotracheal Stenosis
Orally Inhaled Drug Particle Transport in Computerized Models of Laryngotracheal Stenosis: Otolaryngology–Head and Neck Surgery, Ahead of Print. ObjectiveAdjuvant management for laryngotracheal stenosis (LTS) may involve inhaled corticosteroids, but metered dose inhalers are designed for pulmonary drug delivery. Comprehensive analyses of drug particle deposition efficiency for orally inhaled corticosteroids in the stenosis of LTS subjects are lacking.Study DesignDescriptive research.SettingAcademic…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:47

The role of brachytherapy for margin control in oral tongue squamous cell carcinoma
The role of brachytherapy for margin control in oral tongue squamous cell carcinoma: AbstractBackgroundThe aim of this study is to assess the feasibility and effectiveness of using peri-operative brachytherapy (BRTx) for positive/narrow margins present post primary surgical resection of oral tongue squamous cell carcinoma (OTSCC). MethodsProspective single-centre study of patients with OTSCC (T1–3, N0–3, M0) treated with resection of primary tumour ± regional nodal resection…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:43

The Janus-like role of proline metabolism in cancer
The Janus-like role of proline metabolism in cancer:

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:43

Reconstitution of IgG Subclasses Following Immunoglobulin Administration in Adult Patients with Common Variable Immune Deficiency
Reconstitution of IgG Subclasses Following Immunoglobulin Administration in Adult Patients with Common Variable Immune Deficiency: Background: Immunoglobulin (Ig) therapy reduces the frequency and severity of infection among patients with antibody deficiency disorders. However, a subset of patients lacks adequate clinical response. Objective: The purpose of this study was to determine in adult common variable immune deficiency (CVID) patients (A) if lack of clinical response to Ig therapy correlates…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:43

Bone vitality and inflammation
The first quantitative histomorphological analyses of bone vitality and inflammation in surgical specimens of patients with medication-related osteonecrosis of the jaw.: Related ArticlesThe first quantitative histomorphological analyses of bone vitality and inflammation in surgical specimens of patients with medication-related osteonecrosis of the jaw.J Oral Pathol Med. 2020 Sep 18;:Authors: Mamilos A, Spörl S, Spanier G, Ettl T, Brochhausen C, Klingelhöffer CAbstract BACKGROUND: Purpose…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:42

Risk Factors for Cisplatin-Induced Nephrotoxicity
Risk Factors for Cisplatin-Induced Nephrotoxicity: A Multicenter Retrospective Study: Conclusions: Our results suggest that high-dose CDDP and comorbidities of cardiac disease and hypertension are independent risk factors for CDDP nephrotoxicity. Therefore, close monitoring of serum creatinine values during CDDP treatment is recommended for patients with these risk factors. In addition, Mg supplementation and administration of diuretics might be effective for prevention of CDDP nephrotoxicity.Oncology…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:26

Predictive Value of 18F-Fluorodeoxyglucose Positron Emission Tomography or Positron Emission Tomography/Computed Tomography for Assessment of Occult Lymph Node Metastasis in Non-Small Cell Lung Cancer
Predictive Value of 18F-Fluorodeoxyglucose Positron Emission Tomography or Positron Emission Tomography/Computed Tomography for Assessment of Occult Lymph Node Metastasis in Non-Small Cell Lung Cancer: Conclusion: The current meta-analysis showed a moderate sensitivity and specificity of18F FDG PET or PET/CT for the prediction of OLNM in NSCLC patients. The DOR was low and the likelihood ratio scatter-gram indicated that18F FDG PET or PET/CT might not be useful for the prediction of OLNM in NSCLC…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:25

Triiodothyronine use in hypothyroidism and its effects on cancer and mortality.
Triiodothyronine use in hypothyroidism and its effects on cancer and mortality.: CONCLUSIONS: In this large Swedish long-term register-based study, the use of T3 did not lead to increased breast cancer incidence, any cancer incidence, all-cause mortality, any cancer mortality, or breast cancer mortality compared to T4 use. Somewhat surprisingly, there was evidence of lower mortality in T3 users in models adjusting for dose, potentially an artifact of underlying associations between dose and health…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:23

High Expression of MMP-9 in Primary Tumors and High Preoperative MPO in Serum Predict Improved Prognosis in Colorectal Cancer with Operable Liver Metastases.
High Expression of MMP-9 in Primary Tumors and High Preoperative MPO in Serum Predict Improved Prognosis in Colorectal Cancer with Operable Liver Metastases.: CONCLUSION: Low preoperative MPO in serum might identify patients at high risk of recurrence and death after resection of colorectal liver metastases. Elevated preoperative MPO and high expression of MMP-9 in colorectal tumor tissue indicate an improved prognosis. The use of these biomarkers should be adjusted according to clinical characteristics….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:17

High Expression of MMP-9 in Primary Tumors and High Preoperative MPO in Serum Predict Improved Prognosis in Colorectal Cancer with Operable Liver Metastases
High Expression of MMP-9 in Primary Tumors and High Preoperative MPO in Serum Predict Improved Prognosis in Colorectal Cancer with Operable Liver Metastases: Conclusion: Low preoperative MPO in serum might identify patients at high risk of recurrence and death after resection of colorectal liver metastases. Elevated preoperative MPO and high expression of MMP-9 in colorectal tumor tissue indicate an improved prognosis. The use of these biomarkers should be adjusted according to clinical characteristics.Oncology…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:16

Lenvatinib-Induced Tumor-Related Hemorrhages in Patients with Large Hepatocellular Carcinomas
Lenvatinib-Induced Tumor-Related Hemorrhages in Patients with Large Hepatocellular Carcinomas: Conclusion: It becomes clear that lenvatinib treatment brings about tumor-related hemorrhages despite rapid suppression of tumor blood flow. We speculate that lenvatinib quickly blocks the feeding circulation, resulting in tumor hemorrhage by necrosis. Clinicians should pay careful attention to the development of life-threatening hemorrhages when treating large HCCs with lenvatinib.Oncology (Source: Oncology)…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:16

The City Gesture Checklist: The development of a novel gesture assessment
The City Gesture Checklist: The development of a novel gesture assessment: AbstractBackgroundPeople with aphasia rely on gesture more than healthy controls to get their message across, but use a limited range of gesture types. Gesture therapy is thus a potential avenue of intervention for people with aphasia. However, currently no gesture assessment evaluates how they use gesture. Such a tool could inform therapy targets and measure outcomes. In gesture research, many different coding categories…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:13

Dementia knowledge
Dementia knowledge, attitudes and training needs of speech–language pathology students and practitioners: A countrywide study: AbstractBackgroundDue to dementia‐related communication difficulties, speech–language pathologists (SLPs) play a significant role in supporting individuals with dementia and their caregivers. Nevertheless, SLP practitioners may not have received adequate dementia training during their undergraduate programme and skills updating post‐qualification. Investigating the knowledge,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:12

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
UK clinicians’ views on the use of formulations for the management of BPSD: a multidisciplinary survey.Aging & Mental Health: Table of Contents: Taylor and Francis15hAn easily adaptable validated risk score predicts cancer-specific survival in stage II colon cancer.Acta Oncologica: Table of Contents: Taylor and Francis1dCOVID-19 worry, mental health indicators, and preparedness for future care needs across the adult lifespan.Aging & Mental Health: Table of Contents: Taylor and Francis1dHealth-related…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:45

The enigma of Oligocene climate and global surface temperature evolution
The enigma of Oligocene climate and global surface temperature evolution [Earth, Atmospheric, and Planetary Sciences]: Falling atmospheric CO2 levels led to cooling through the Eocene and the expansion of Antarctic ice sheets close to their modern size near the beginning of the Oligocene, a period of poorly documented climate. Here, we present a record of climate evolution across the entire Oligocene (33.9 to 23.0 Ma)…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:40

Αφαίρεση διαφημίσεων

Health benefits of on-road transportation pollution control programs in China [Sustainability Science]
Health benefits of on-road transportation pollution control programs in China [Sustainability Science]: China started to implement comprehensive measures to mitigate traffic pollution at the end of 1990s, but the comprehensive effects, especially on ambient air quality and public health, have not yet been systematically evaluated. In this study, we analyze the effects of vehicle emission control measures on ambient air pollution and…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:39

Asbestos induces mesothelial cell transformation via HMGB1-driven autophagy [Cell Biology]
Asbestos induces mesothelial cell transformation via HMGB1-driven autophagy [Cell Biology]: Asbestos causes malignant transformation of primary human mesothelial cells (HM), leading to mesothelioma. The mechanisms of asbestos carcinogenesis remain enigmatic, as exposure to asbestos induces HM death. However, some asbestos-exposed HM escape cell death, accumulate DNA damage, and may become transformed. We previously demonstrated that, upon asbestos exposure, HM and…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:37

Speech can produce jet-like transport relevant to asymptomatic spreading of virus
Speech can produce jet-like transport relevant to asymptomatic spreading of virus [Applied Physical Sciences]: Many scientific reports document that asymptomatic and presymptomatic individuals contribute to the spread of COVID-19, probably during conversations in social interactions. Droplet emission occurs during speech, yet few studies document the flow to provide the transport mechanism. This lack of understanding prevents informed public health guidance for risk reduction and…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:37

Driver mutations of the adenoma-carcinoma sequence govern the intestinal epithelial global translational capacity [Cell Biology]
Driver mutations of the adenoma-carcinoma sequence govern the intestinal epithelial global translational capacity [Cell Biology]: Deregulated global mRNA translation is an emerging feature of cancer cells. Oncogenic transformation in colorectal cancer (CRC) is driven by mutations in APC, KRAS, SMAD4, and TP53, known as the adenoma-carcinoma sequence (ACS). Here we introduce each of these driver mutations into intestinal organoids to show that they are modulators…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:36

Physics of virus transmission by speaking droplets
Physics of virus transmission by speaking droplets [Biophysics and Computational Biology]: To make the physics of person-to-person virus transmission from emitted droplets of oral fluid while speaking easily understood, we present simple and transparent algebraic equations that capture the essential physics of the problem. Calculations with these equations provide a straightforward way of determining whether emitted droplets remain airborne or rapidly…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:36

Unethical amnesia responds more to instrumental than to hedonic motives
Unethical amnesia responds more to instrumental than to hedonic motives [Economic Sciences]: Humans care about morality. Yet, they often engage in actions that contradict their moral self. Unethical amnesia is observed when people do not remember or remember less vividly these actions. This paper explores two reasons why individuals may experience unethical amnesia. Forgetting past unethical behavior may be motivated by purely…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:35

The bacillus Calmette-Guerin vaccination allows the innate immune system to provide protection from severe COVID-19 infection [Biological Sciences]
The bacillus Calmette-Guerin vaccination allows the innate immune system to provide protection from severe COVID-19 infection [Biological Sciences]: We have read the paper by Escobar et al. (1), and we also support a similar hypothesis (2), which arose from the observation of the so-called Iberian Peninsula paradox. As they also report, in the same geographical area with similar socioeconomic conditions, completely different and particularly high mortality rates have…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:35

Sudden irreversible hearing loss post COVID-19
Sudden irreversible hearing loss post COVID-19: Sudden onset sensorineural hearing loss (SSNHL) is frequently seen by otolaryngologists. The exact pathophysiology of the disease is still unknown, with the most likely causative factor being following a viral infection. Immediate steroids are the best treatment to improve prognosis. Despite a plethora of papers in the literature describing SSNHL, there are only a few reported cases of hearing loss following COVID-19, none of which have been reported…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:33

Association between hyperemesis gravidarum and psychological symptoms, psychosocial outcomes and infant bonding: a two-point prospective case-control multicentre survey study in an inner city setting
Association between hyperemesis gravidarum and psychological symptoms, psychosocial outcomes and infant bonding: a two-point prospective case-control multicentre survey study in an inner city setting: Objectives To assess if there is any association between hyperemesis gravidarum (HG), psychological morbidity and infant bonding and to quantify any psychosocial consequences of HG.Design Two-point prospective case–control, multicentre survey study with antenatal and postnatal data collection.Setting…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:32

Chemotherapy combined with radiotherapy for successful treatment of angioimmunoblastic T-cell lymphoma
Chemotherapy combined with radiotherapy for successful treatment of angioimmunoblastic T-cell lymphoma: a case report: The incidence of angioimmunoblastic T-cell lymphoma is rare worldwide, and it has a poor prognosis. There is no proven or standard first-line therapy that works for the majority of patients with angioimmunobla…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:32

Optical Coherence Tomography Biomarkers of the Outer Blood—Retina Barrier in Patients with Diabetic Macular Oedema
Optical Coherence Tomography Biomarkers of the Outer Blood—Retina Barrier in Patients with Diabetic Macular Oedema: Background. Numerous studies confirmed the main role of the inner blood-retinal barrier in the development of Diabetic Macular Oedema (DMO). Lately, the focus of research shifted towards the external retinal barrier with potential involvement in the pathogenesis of DMO. Objective. We aim to identify the OCT changes of the external blood-retinal barrier in patients with DMO and to define…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:31

Would Cortisol Measurements Be a Better Gauge of Hydrocortisone Replacement Therapy? Congenital Adrenal Hyperplasia as an Exemplar
Would Cortisol Measurements Be a Better Gauge of Hydrocortisone Replacement Therapy? Congenital Adrenal Hyperplasia as an Exemplar: There is an increase in mortality and morbidity as well as poor quality of life in patients with congenital adrenal hyperplasia (CAH) and other causes of adrenal insufficiency. Glucocorticoid replacement therapy should aim to replace the missing cortisol as close as possible to the normal circadian rhythm using hydrocortisone. Dosing should be based on the individual’s…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:30

Association of HIVEP3 Gene and Lnc RNA with Femoral Neck Bone Mineral Content and Hip Geometry
Association of HIVEP3 Gene and Lnc RNA with Femoral Neck Bone Mineral Content and Hip Geometry by Genome-Wide Association Analysis in Chinese People: Purpose. GWAS has successfully located and analyzed the pathogenic genes of osteoporosis. Genetic studies have found that heritability of BMD is 50%–85% while the other half is caused by hip geometric parameters and tissue horizontal characteristics. This study was designed to study the GWAS of osteoporosis in Shanghai Han population. Methods. We collected…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:30

Pertussis Vaccine Protective Effectiveness in Children
Assessment of Pertussis Vaccine Protective Effectiveness in Children in the Amhara Regional State, Ethiopia: Background. Bordetella pertussis is a human pathogen which causes pertussis, or whooping cough. The diphtheria-tetanus-pertussis immunization has significantly reduced the morbidity and mortality of pertussis globally. However, higher prevalence and resurgence of pertussis cases among both vaccinated and unvaccinated people has raised questions on the effectiveness of pertussis vaccine over…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:29

Possible Susceptibility Genes for Intervention against Chemotherapy-Induced Cardiotoxicity
Possible Susceptibility Genes for Intervention against Chemotherapy-Induced Cardiotoxicity: Recent therapeutic advances have significantly improved the short- and long-term survival rates in patients with heart disease and cancer. Survival in cancer patients may, however, be accompanied by disadvantages, namely, increased rates of cardiovascular events. Chemotherapy-related cardiac dysfunction is an important side effect of anticancer therapy. While advances in cancer treatment have increased patient…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:29

Endometrial Cancer Cells Promote M2-Like Macrophage Polarization by Delivering Exosomal miRNA-21 under Hypoxia Condition
Endometrial Cancer Cells Promote M2-Like Macrophage Polarization by Delivering Exosomal miRNA-21 under Hypoxia Condition: Increasing evidence has demonstrated that hypoxia was an aggressive feature in endometrial cancer (EC), which is significantly associated with the tumor grade, lymph node metastasis, and tumor resistance to chemotherapy. However, the relationship between hypoxia and the immune microenvironment in EC is not very clear. Exosomes are small membrane vesicles secreted from a variety…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:28

Not Your Common Athletic Heart Problem: Using Coronary CTA to Visualize Spontaneous Coronary Artery Dissection
Not Your Common Athletic Heart Problem: Using Coronary CTA to Visualize Spontaneous Coronary Artery Dissection: A 19-year-old healthy male collegiate athlete presented with typical anginal symptoms after running a 5K race. He had complained of similar symptoms off and on for the past month. On presentation, troponin was 0.12 ng/ml (reference value 

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:28

Ameloblastic Carcinoma with Calcification
Ameloblastic Carcinoma with Calcification: A Rare Case Report in the Mandible and Literature Review: Ameloblastic carcinoma (AC) is a scarce malignant tumor which is more prevalent in the mandible than the maxilla. It occurs in a wide range of age groups, and there is a sex predilection in males. AC shows specific microscopic features and requires more aggressive surgical treatment plans in comparison with conventional ameloblastoma. Radiographically, AC resembles ameloblastoma except that it rarely…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:28

Association between Circulating B-Type Natriuretic Peptide and Diabetic Peripheral Neuropathy: A Cross-Sectional Study of a Chinese Type 2 Diabetic Population
Association between Circulating B-Type Natriuretic Peptide and Diabetic Peripheral Neuropathy: A Cross-Sectional Study of a Chinese Type 2 Diabetic Population: Cardiovascular disease which is associated with cardiac dysfunction, usually measured with circulating levels of B-type natriuretic peptide (BNP), has been associated with incidence and progression of diabetic peripheral neuropathy (DPN). The potential relationship of circulating physiological levels of BNP with DPN, however, has not been…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:27

The Effect of Selective Laser Trabeculoplasty on Intraocular Pressure in Patients with Dexamethasone Intravitreal Implant-Induced Elevated Intraocular Pressure
The Effect of Selective Laser Trabeculoplasty on Intraocular Pressure in Patients with Dexamethasone Intravitreal Implant-Induced Elevated Intraocular Pressure: Introduction. To assess the safety and efficacy of selective laser trabeculoplasty (SLT) for ocular hypertension (OHT) induced by a dexamethasone (DEX) intravitreal implant. Materials and Methods. We performed a retrospective study of patients who underwent an SLT procedure for ocular hypertension induced by injection of a DEX intravitreal…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:27

Αφαίρεση διαφημίσεων

Hypoxia-Induced Glioma-Derived Exosomal miRNA-199a-3p Promotes Ischemic Injury of Peritumoral Neurons by Inhibiting the mTOR Pathway
Hypoxia-Induced Glioma-Derived Exosomal miRNA-199a-3p Promotes Ischemic Injury of Peritumoral Neurons by Inhibiting the mTOR Pathway: The underlying molecular mechanisms that the hypoxic microenvironment could aggravate neuronal injury are still not clear. In this study, we hypothesized that the exosomes, exosomal miRNAs, and the mTOR signaling pathway might be involved in hypoxic peritumoral neuronal injury in glioma. Multimodal radiological images, HE, and HIF-1α staining of high-grade glioma (HGG)…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:26

Combined Treatment of Non-Small-Cell Lung Cancer Using Shenyi Capsule and Platinum-Based Chemotherapy: A Meta-Analysis and Systematic Review
Combined Treatment of Non-Small-Cell Lung Cancer Using Shenyi Capsule and Platinum-Based Chemotherapy: A Meta-Analysis and Systematic Review: Background.The efficacy and safety of combined treatment of non-small-cell lung cancer (NSCLC) using Shenyi capsules and platinum-based chemotherapy were comprehensively evaluated. Methods. A computer-based search was used to identify reports on clinical randomized controlled trials (RCTs) on this combined treatment for NSCLC from the PubMed, Embase, Cochrane…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:26

Increased Succinate Accumulation Induces ROS Generation in In Vivo Ischemia/Reperfusion-Affected Rat Kidney Mitochondria
Increased Succinate Accumulation Induces ROS Generation in In Vivo Ischemia/Reperfusion-Affected Rat Kidney Mitochondria: Mitochondria are recognized as main reactive oxygen species (ROS) producers, involving ROS generation by mitochondrial complexes I and III. Lately, the focus has been shifting to the ROS generation by complex II. Contribution of complex II (SDH) to ROS generation still remains debatable, especially in in vivo settings. Moreover, it is not completely defined at what time of ischemia…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:26

Acupuncture for Chronic Stable Angina Pectoris
Investigating Prescriptions and Mechanisms of Acupuncture for Chronic Stable Angina Pectoris: An Association Rule Mining and Network Analysis Study: Chronic stable angina pectoris (CSAP) is a worldwide cardiovascular disease that severely affects people’s quality of life and causes serious cardiovascular accidents. Although acupuncture had been confirmed as a potential adjunctive treatment for CSAP, the basic rules and mechanisms of acupoints were little understood. We conducted a systematic search…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:25

The Distal Biceps Femoris Muscle
A Cadaveric Study of the Distal Biceps Femoris Muscle in relation to the Normal and Variant Course of the Common Peroneal Nerve: A Possible Cause of Common Peroneal Entrapment Neuropathy: The most frequent mononeuropathy in the lower extremity has been reported as the common peroneal nerve entrapment neuropathy (CPNe) around the head and neck of the fibula, although the mechanism of the neuropathy in this area cannot be fully explained. Therefore, the aim of this cadaveric study was to evaluate the…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:25

Increased Expression of TIGIT/CD57 in Peripheral Blood/Bone Marrow NK Cells in Patients with Chronic Myeloid Leukemia
Increased Expression of TIGIT/CD57 in Peripheral Blood/Bone Marrow NK Cells in Patients with Chronic Myeloid Leukemia: The antitumor activity of NK cells in patients with chronic myeloid leukemia (CML) is inhibited by the leukemia microenvironment. Recent studies have identified that the expression of TIGIT, CD57, and KLRG1 is related to the function, maturation, and antitumor capabilities of NK cells. However, the characteristics of the expression of these genes in the peripheral blood (PB) and…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:24

Goat weed (Ageratum conyzoides L.), or bandotan
Medicinal Effect, In Silico Bioactivity Prediction, and Pharmaceutical Formulation of Ageratum conyzoides L.: A Review: Goat weed (Ageratum conyzoides L.), or bandotan in Indonesia, is an herbaceous plant that broadly grows up in both subtropical as well as tropical areas. This herb contains many phytoconstituents which have many benefits in different aspects. The essential oil contains phytochemicals such as phenol, phenolic ester, and coumarin, whereas many compounds can been identified in the…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:24

Hydroxychloroquine in Patients
The Outcome of Hydroxychloroquine in Patients Treated for COVID-19: Systematic Review and Meta-Analysis: Background. The pandemic of coronavirus disease 2019 (COVID‐19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) resulted in an unprecedented public health challenge worldwide. Despite urgent and extensive global efforts, the existing evidence is inconclusive regarding the medications used for the treatment of COVID-19. Purpose. To generate an up-to-date evidence for the…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:23

Dissociative Amnesia with Dissociative Fugue and Psychosis
Dissociative Amnesia with Dissociative Fugue and Psychosis: a Case Report from a 25-Year-Old Ethiopian Woman: Introduction. The case after exposure to intense traumatic events manifests signs and symptoms of dissociative amnesia with a dissociative fugue and schizophrenia. The psychotic symptoms we found, in this case, were very complicated and mimicking primary psychotic disorders. Therefore, this might be a good forum for the scientific world to learn from this case report, how psychotic disorders…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:23

Neutrophil-to-lymphocyte ratio (NLR) in patients with oropharyngeal cancer
Prognostic significance of pre-treatment neutrophil-to-lymphocyte ratio (NLR) in patients with oropharyngeal cancer treated with radiotherapy: British Journal of Cancer, Published online: 14 October 2020; doi:10.1038/s41416-020-01106-xPrognostic significance of pre-treatment neutrophil-to-lymphocyte ratio (NLR) in patients with oropharyngeal cancer treated with radiotherapy

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:20

Ascites management by cell-free concentrated ascites reinfusion therapy during recovery from drug-induced acute liver injury: a case report
Ascites management by cell-free concentrated ascites reinfusion therapy during recovery from drug-induced acute liver injury: a case report: The symptoms of drug-induced hepatic injury are manifold; however, the presence of ascites indicates a severe disease condition. The rapid accumulation of ascites is distressing and requires palliative treatme…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:20

Σήμανση της παραπάνω ενότητας ως αναγνωσμένης

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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia,

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Medicine by Alexandros G. Sfakianakis

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Neurocutaneous melanocytosis (melanosis)
Neurocutaneous melanocytosis (melanosis): AbstractNeurocutaneous melanosis (NCM; MIM # 249400; ORPHA: 2481], first reported by the Bohemian pathologist Rokitansky in 1861, and now more precisely defined as neurocutaneous melanocytosis, is a rare, congenital syndrome characterised by the association of (1) congenital melanocytic nevi (CMN) of the skin with overlying hypertrichosis, presenting as (a) large (LCMN) or giant and/or multiple (MCMN) melanocytic lesions (or both; sometimes associated with…

Medicine by Alexandros G.Sfakianakis

09:27

What is dimethoate used for? Dimethoate is used to kill mites and insects systemically and on contact….Dimethoate Poisoning with Early Onset Intermediate Syndrome Cardiotoxicity and Hypothermia
Severe dimethoate self-poisoning causes a syndrome characterized by marked hypotension with progression to distributive shock and death despite standard treatments. A lack of cardiotoxicity until just before death suggests that the mechanism is of OP-induced low systemic vascular resistance (SVR).Nov 11, 2008Hypotension in Severe Dimethoate Self-Poisoning – NCBICase Report – (2020) Volume 10, Issue 5 Curious Case of Dimethoate Poisoning with Early Onset Intermediate Syndrome, Cardiotoxicity and Hypothermia:…

Medicine by Alexandros G.Sfakianakis

09:25

Organophosphate Poisoning PDF
Organophosphate Poisoning Complicated by RhabdomyolysisInduced Acute Kidney Injury A Case Report and Review of Literature: JB Gunasena, ST De Silva ABSTRACTBackground: Rhabdomyolysis induced acute kidney injury (AKI) following organophosphate poisoning is a rarecomplication. The mechanism responsible is uncertain.Case report: A 42 years old male was admitted to a tertiary care hospital in Sri Lanka after deliberate self-ingestion ofCalcron® (Profenophos, an organophosphorus pesticide). He developed…

Medicine by Alexandros G.Sfakianakis

09:23

Partial internal biliary diversion
Effects of partial internal biliary diversion on long-term outcomes in patients with progressive familial intrahepatic cholestasis: experience in 44 patients.: Related ArticlesEffects of partial internal biliary diversion on long-term outcomes in patients with progressive familial intrahepatic cholestasis: experience in 44 patients.Pediatr Surg Int. 2020 May;36(5):603-610Authors: Foroutan HR, Bahador A, Ghanim SM, Dehghani SM, Anbardar MH, Fattahi MR, Forooghi M, Azh O, Tadayon A, Sherafat A, Yaghoobi…

Medicine by Alexandros G.Sfakianakis

09:21

Biliary ascariasis and severe bacterial outcomes
Biliary ascariasis and severe bacterial outcomes: Report of three cases from a paediatric hospital in Brazil.: Related ArticlesBiliary ascariasis and severe bacterial outcomes: Report of three cases from a paediatric hospital in Brazil.Int J Infect Dis. 2020 Jun;95:115-117Authors: de Almeida BL, Silva DV, do Rosário MS, Gonçalves BSD, Nunes MG, Ney ALCM, Silvany C, de Siqueira ICAbstract INTRODUCTION: Biliary ascariasis, although uncommon, can lead to infectious complications and severe…

Medicine by Alexandros G.Sfakianakis

09:20

The Fussy Baby Network® (FBN), a program supporting families struggling with infant crying and related concerns
Increasing parenting self-efficacy: The Fussy Baby Network® intervention.: Related ArticlesIncreasing parenting self-efficacy: The Fussy Baby Network® intervention.Infant Ment Health J. 2020 03;41(2):232-245Authors: Gilkerson L, Burkhardt T, Katch LE, Hans SLAbstract High levels of infant crying place families at risk for disrupted relationships, parenting stress, and even for child maltreatment. We conducted an evaluation of the Fussy Baby Network® (FBN), a program supporting families…

Medicine by Alexandros G.Sfakianakis

09:17

Birth Weight and the Development of Functional Gastrointestinal Disorders in Infants.
Birth Weight and the Development of Functional Gastrointestinal Disorders in Infants.: Related ArticlesBirth Weight and the Development of Functional Gastrointestinal Disorders in Infants.Pediatr Gastroenterol Hepatol Nutr. 2020 Jul;23(4):366-376Authors: Baldassarre ME, Di Mauro A, Salvatore S, Tafuri S, Bianchi FP, Dattoli E, Morando L, Pensabene L, Meneghin F, Dilillo D, Mancini V, Talarico V, Tandoi F, Zuccotti G, Agosti M, Laforgia NAbstract Purpose: To assess the association between…

Medicine by Alexandros G.Sfakianakis

09:15

Low prevalence of infantile functional gastrointestinal disorders (FGIDs)
Low prevalence of infantile functional gastrointestinal disorders (FGIDs) in a multi-ethnic Asian population.: Related ArticlesLow prevalence of infantile functional gastrointestinal disorders (FGIDs) in a multi-ethnic Asian population.Pediatr Neonatol. 2020 Aug 16;:Authors: Chew KS, Em JM, Koay ZL, Jalaludin MY, Ng RT, Lum LCS, Lee WSAbstract BACKGROUND: Functional gastrointestinal disorders (FGIDs) are common in children. The prevalence of FGIDs varies across the world but is unknown…

Medicine by Alexandros G.Sfakianakis

09:15

DNA repair targeted therapy
Plants, Vol. 9, Pages 1350: Identification and Analysis of NBS-LRR Genes in Actinidia chinensis GenomePlants, Vol. 9, Pages 1350: Identification and Analysis of NBS-LRR Genes in Actinidia chinensis Genome Plants doi: 10.3390/plants9101350 Authors: Tao Wang Zhan-Hui Jia Ji-Yu Zhang Min Liu Zhong-Ren Guo Gang Wang Nucleotide-binding site and leucine-rich repeat (NBS-LRR) genes represent the most important disease resistance genes in plants. The genome sequence of kiwifruit (Actinidia chinensis) provides…

Medicine by Alexandros G.Sfakianakis

09:15

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Plants, Vol. 9, Pages 1350: Identification and Analysis of NBS-LRR Genes in Actinidia chinensis GenomePlants, Vol. 9, Pages 1350: Identification and Analysis of NBS-LRR Genes in Actinidia chinensis Genome Plants doi: 10.3390/plants9101350 Authors: Tao Wang Zhan-Hui Jia Ji-Yu Zhang Min Liu Zhong-Ren Guo Gang Wang Nucleotide-binding site and leucine-rich repeat (NBS-LRR) genes represent the most important disease resistance genes in plants. The genome sequence of kiwifruit (Actinidia chinensis) provides…

Medicine by Alexandros G.Sfakianakis

09:15

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Clinical GeneticsExploring genotype‐phenotype relationships in the CDKL5 deficiency disorder using an international datasetABSTRACT Characterised by early‐onset seizures, global developmental delay and severe motor deficits, CDKL5 deficiency disorder is caused by pathogenic variants in the cyclin‐dependent kinase‐like 5 gene. Previous efforts to investigate genotype‐phenotype relationships have been limited due to small numbers of recurrent mutations and small cohort sizes. Using data from the…

Medicine by Alexandros G.Sfakianakis

09:15

Intralesional methotrexate
Intralesional methotrexate in dermatology: diverse indications and practical considerations: AbstractIntralesional methotrexate (IL‐MTX) is a long‐established treatment, which is arguablyunderutilized by dermatologists. We describe the underlying evidence base and practical considerations for its broad range of cutaneous indications,including in cutaneous oncology (keratoacanthomas, squamous cell carcinomas, lymphomas), inflammatory dermatology (nail psoriasis, plaque psoriasis, pyoderma gangrenosum,…

Medicine by Alexandros G.Sfakianakis

08:49

Intralesional immunotherapy for molluscum contagiosum
Intralesional immunotherapy for molluscum contagiosum: A review: AbstractMolluscum contagiosum (MC) is a common cutaneous viral infection with no standard treatment. The virus responsible for MC is thought to be cleared by cell mediated immunity (CMI). Intralesional immunotherapy that stimulates CMI has been shown to be an effective treatment for other cutaneous viruses. In this review, we evaluate the efficacy and safety of intralesional immunotherapy in the treatment of MC. Articles met inclusion…

Medicine by Alexandros G.Sfakianakis

08:48

Standardizing a volume benchmark for cerebrospinal fluids for optimal diagnostic accuracy
Standardizing a volume benchmark for cerebrospinal fluids for optimal diagnostic accuracy: AbstractIntroductionCerebral spinal fluid (CSF) cytomorphologic analysis remains the gold standard in the evaluation of malignant leptomeningeal involvement. However, collection of optimal volumes for adequate cytomorphologic evaluation is not standardized. Our study investigated optimal CSF volumes that result in a significant diagnostic result.MethodsA total of 4114 samples were retrospectively identified…

Medicine by Alexandros G.Sfakianakis

08:48

Adenomatous neuroendocrine tumors of the middle ear (MEANTs)
Adenomatous neuroendocrine tumors of the middle ear (MEANTs) with local invasion and lymph nodes metastasis: A brief report of a rare neoplasm: AbstractAdenomatous neuroendocrine tumors of the middle ear (MEANTs) are very rare neoplasms which are composed of both epithelial and neuroendocrine components. They have mostly bland histology and indolent biological behavior, yet they may recur and metastasize. Here we present a case of MEANT with ipsilateral local brain, bone and nerve invasion and bilateral…

Medicine by Alexandros G.Sfakianakis

08:47

Management of transmodiolar and transmacular cochleovestibular schwannomas
Management of transmodiolar and transmacular cochleovestibular schwannomas with and without cochlear implantation: AbstractIntroductionHearing rehabilitation with cochlear implants has attracted increasing interest also for patients with cochleovestibular schwannoma. The authors report their experience with the surgical management of tumors with rare transmodiolar or transmacular extension and outcomes after cochlear implantation (CI). MethodsThis retrospective case series included…

Medicine by Alexandros G.Sfakianakis

08:47

Association of Estrogen Receptor 1 and Tumor Necrosis Factor α Polymorphisms with Temporomandibular Joint Anterior Disc Displacement without Reduction
Association of Estrogen Receptor 1 and Tumor Necrosis Factor α Polymorphisms with Temporomandibular Joint Anterior Disc Displacement without Reduction: Objectives. The aim of this study was to investigate the role of ESR1 rs1643821 and TNF-α rs1800629 as potential genetic factors regulating anterior disc displacement without reduction-mediated inflammatory pathway. Background. The temporomandibular joint is a complex synovial joint that allows mandibular movement in three directions. Although temporomandibular…

Medicine by Alexandros G.Sfakianakis

08:45

Primary Intraosseous Squamous Cell Carcinoma Involving the Jaw Bones:
Primary Intraosseous Squamous Cell Carcinoma Involving the Jaw Bones: A Systematic Review and Update: AbstractPrimary intraosseous oral squamous cell carcinoma (PIOSCC) is a rare malignant neoplasm that affects the jaws. Despite its aggressive biological behavior, there are no studies that evaluated the clinicopathological features of this tumor and parameters associated with its prognosis. The objective of the present study was to conduct a systematic review of the available data on oral and maxillofacial…

Medicine by Alexandros G.Sfakianakis

08:44

Lymphocyte predominant Hodgkin lymphoma, antigen‐driven after all?
Lymphocyte predominant Hodgkin lymphoma, antigen‐driven after all?: AbstractNodular lymphocyte predominant Hodgkin lymphoma (NLPHL) was suggested as an entity separate from other types of Hodgkin lymphoma 40 years ago and recognized in the WHO classification in 2001. Based on its relatively benign course with late distant relapses, relation with lymph node hyperplasia with progressively transformed germinal centers, presence of clonal immunoglobulin gene rearrangements with somatic hypermutations…

Medicine by Alexandros G.Sfakianakis

08:44

SETDB1 promotes gastric carcinogenesis and metastasis via upregulation of CCND1 and MMP9 expression
SETDB1 promotes gastric carcinogenesis and metastasis via upregulation of CCND1 and MMP9 expression: AbstractSETDB1 is a histone lysine methyltransferase that has critical roles in cancers. However, its potential role in gastric cancer (GC) remains obscure. Here, we mainly investigate the clinical significance and the possible role of SETDB1 in GC. We find that SETDB1 expression is upregulated in GC tissues and its high‐level expression was a predictor of poor prognosis in patients. Overexpression…

Medicine by Alexandros G.Sfakianakis

08:43

Microglia/macrophages express alternative proangiogenic factors depending on granulocyte content in human glioblastoma
Microglia/macrophages express alternative proangiogenic factors depending on granulocyte content in human glioblastoma: AbstractMyeloid cells are an inherent part of the microenvironment of glioblastoma multiforme (GBM). There is growing evidence for their participation in mechanisms of tumor escape, especially in development of resistance following initially promising anti‐VEGF/VEGFR treatment. Thus, we sought to define the capability of myeloid cells to contribute to the expression of proangiogenic…

Medicine by Alexandros G.Sfakianakis

08:43

Evaluation of myostatin as a possible regulator and marker of skeletal muscle–cortical bone interaction in adults
Evaluation of myostatin as a possible regulator and marker of skeletal muscle–cortical bone interaction in adults: AbstractIntroductionBone mass was recently reported to be related to skeletal muscle mass in humans, and a decrease in cortical bone is a risk factor for osteoporosis. Because circulating myostatin is a factor that primarily controls muscle metabolism, this study examined the role of myostatin in bone mass–skeletal muscle mass interactions. MethodsThe subjects were…

Medicine by Alexandros G.Sfakianakis

08:42

Effect of etelcalcetide on parathyroid hormone secretion by primary hyperparathyroidism patient-derived primary parathyroid cells
Effect of etelcalcetide on parathyroid hormone secretion by primary hyperparathyroidism patient-derived primary parathyroid cells: AbstractIntroductionEtelcalcetide (Parsabiv®, AMG 416/ONO-5163) is a novel allosteric modulator for the calcium-sensing receptor approved for hemodialysis patients with secondary hyperparathyroidism of uremia. Etelcalcetide reduced parathyroid hormone levels in hemodialysis patients with secondary hyperparathyroidism of uremia in clinical studies. However, its direct…

Medicine by Alexandros G.Sfakianakis

08:41

The role of immune checkpoint inhibitor therapy in advanced adrenocortical carcinoma
The role of immune checkpoint inhibitor therapy in advanced adrenocortical carcinoma revisited: review of literature: AbstractPurposeAdrenocortical carcinoma (ACC) is a rare disease with few therapeutic options. There is an urgency of new effective therapeutic options for these patients. The role of immune checkpoint inhibitors (ICI) in advanced ACC patients is still unclear. MethodsWe conducted a MEDLINE search using the following string: adrenocortical carcinoma and immunotherapy…

Medicine by Alexandros G.Sfakianakis

08:36

Translational perspectives to treat Epidermolysis bullosa
Translational perspectives to treat Epidermolysis bullosa – where do we stand?: AbstractEpidermolysis bullosa (EB) is the prototypical example of genetic skin fragility disorders. Genotypic heterogeneity, modifier genes, epigenetic, biochemical and environmental factors alter and determine pathogenic traits and, ultimately, the wide and striking phenotypic variability in EB. Besides the primary structural‐functional defect, chronic tissue damage with induction and dysregulation of inflammatory pathways…

Medicine by Alexandros G.Sfakianakis

08:35

Cantilevered resin-bonded fixed partial dentures
Clinical performance of cantilevered resin-bonded fixed partial dentures for single tooth replacement in elderly patients: Journal of International Medical Research, Volume 48, Issue 10, October 2020. ObjectiveTo evaluate the clinical performance of cantilevered resin-bonded fixed partial dentures (CRBFPDs) in single tooth replacement in elderly patients at Qingdao Stomatological Hospital.MethodsIn total, 186 CRBFPDs in 153 patients were made from cobalt-chrome alloy. Panavia F 2.0 was used as a…

Medicine by Alexandros G.Sfakianakis

08:34

Telomerase reverse transcriptase rs2736098 polymorphism is associated with lung cancer: A meta-analysis
Telomerase reverse transcriptase rs2736098 polymorphism is associated with lung cancer: A meta-analysis: Journal of International Medical Research, Volume 48, Issue 10, October 2020. BackgroundA meta-analysis was conducted to determine whether telomerase reverse transcriptase (TERT) rs2736098 polymorphism was related to the incidence of lung cancer.MethodsWe systematically searched the following three electronic databases: PubMed, Embase, and China National Knowledge Infrastructure (CNKI), for relevant…

Medicine by Alexandros G.Sfakianakis

08:34

Cardiac contractility modulation attenuates structural and electrical remodeling in a chronic heart failure rabbit model
Cardiac contractility modulation attenuates structural and electrical remodeling in a chronic heart failure rabbit model: Journal of International Medical Research, Volume 48, Issue 10, October 2020. BackgroundCardiac contractility modulation (CCM) is non-excitatory electrical stimulation for improving cardiac function. This study aimed to evaluate the effects of CCM on structural and electrical remodeling in a rabbit model of chronic heart failure (CHF).MethodsThirty rabbits were randomly divided…

Medicine by Alexandros G.Sfakianakis

08:33

Imaging of bioluminescent Klebsiella pneumoniae induced pulmonary infection
Imaging of bioluminescent Klebsiella pneumoniae induced pulmonary infection in an immunosuppressed mouse model: Journal of International Medical Research, Volume 48, Issue 10, October 2020. ObjectiveTo establish a mouse model of bioluminescent Klebsiella pneumoniae-induced lung infection, under different infection states after pretreatment with various dosages of cyclophosphamide (CTX).MethodsA K. pneumoniae strain carrying the luxCDABE operon was used to infect immunocompetent mice (intraperitoneal…

Medicine by Alexandros G.Sfakianakis

08:33

Serum oestradiol levels are inversely associated with C-reactive protein levels in premenopausal women, but not postmenopausal women
Serum oestradiol levels are inversely associated with C-reactive protein levels in premenopausal women, but not postmenopausal women: Journal of International Medical Research, Volume 48, Issue 10, October 2020. ObjectiveEpidemiological studies on the association of serum oestradiol levels and inflammatory markers have reported inconsistent and conflicting results. Therefore, we investigated the association between serum oestradiol and high-sensitivity C-reactive protein (CRP) levels in women on…

Medicine by Alexandros G.Sfakianakis

08:32

Large (stage ≥T2b) and locally advanced renal cell carcinoma
Safety and oncological outcomes for large (stage ≥T2b) and locally advanced renal cell carcinoma: comparison between laparoscopic and modified hand-assisted laparoscopic radical nephrectomy: Journal of International Medical Research, Volume 48, Issue 10, October 2020. ObjectiveTo compare the operative and oncologic outcomes between hand-assisted laparoscopic radical nephrectomy (HALRN) and laparoscopic radical nephrectomy (LRN) for large (stage ≥T2b) and locally advanced renal cell carcinoma.MethodsWe…

Medicine by Alexandros G.Sfakianakis

08:32

Risk factors for early postoperative recurrence in single and small hepatitis B virus-associated primary hepatocellular carcinoma
Risk factors for early postoperative recurrence in single and small hepatitis B virus-associated primary hepatocellular carcinoma: Journal of International Medical Research, Volume 48, Issue 10, October 2020. ObjectiveTo investigate the risk factors of early postoperative recurrence in patients with single and small (≤3 cm) hepatitis B virus-associated primary hepatocellular carcinoma (HBV-HCC).MethodsThis retrospective study analyzed patients with single and small HBV-HCC. All patients were followed…

Medicine by Alexandros G.Sfakianakis

08:31

Immune dysfunction in MGAT2‐CDG
Immune dysfunction in MGAT2‐CDG: A clinical report and review of the literature: AbstractGlycosylation is a critical post/peri‐translational modification required for the appropriate development and function of the immune system. As an example, abnormalities in glycosylation can cause antibody deficiency and reduced lymphocyte signaling, although the phenotype can be complex given the diverse roles of glycosylation. Human MGAT2 encodes N‐acetylglucosaminyltransferase II, which is a critical enzyme…

Medicine by Alexandros G.Sfakianakis

08:30

Cutaneous Manifestations in Adult Patients with COVID-19 and Dermatologic Conditions Related to the COVID-19 Pandemic in Health Care Workers
Cutaneous vasculopathy and microthrombus-related changes including acral and sacral lesions, retiform purpura, livedo reticularis, and cutaneous vasculitisCutaneous Manifestations in Adult Patients with COVID-19 and Dermatologic Conditions Related to the COVID-19 Pandemic in Health Care Workers: AbstractPurpose of ReviewCOVID-19 (coronavirus viral disease 2019), due to the novel SARS-CoV-2, may present with different types of cutaneous manifestations of varying pathophysiology. During the ongoing…

Medicine by Alexandros G.Sfakianakis

08:30

The Role of Environmental Exposures in Atopic Dermatitis
The Role of Environmental Exposures in Atopic Dermatitis: AbstractPurpose of ReviewAlthough genetic factors clearly play a role in the development of atopic dermatitis (AD), the recent dramatic increase in the prevalence of AD in low- and middle-income countries is not consistent with only a role of genetic factors. These findings strongly suggest that environmental factors may play an important role in the pathogenesis of AD. Recent FindingsWe reviewed the role of gene-environment…

Medicine by Alexandros G.Sfakianakis

08:29

Strategies for having a more effective and less toxic CAR T-cell therapy for acute lymphoblastic leukemia
Strategies for having a more effective and less toxic CAR T-cell therapy for acute lymphoblastic leukemia: AbstractIn the recent years, using genetically modified T cells has been known as a rapid developing therapeutic approach due to the heartwarming results of clinical trials with patients suffering from relapsed or refractory (R/R) hematologic malignancies such as R/R Acute Lymphoblastic Leukemia (R/R ALL). One of these renowned approaches is Chimeric antigen receptors (CARs). CARs are synthetic…

Medicine by Alexandros G.Sfakianakis

08:28

Mutationssignaturen beim Kopf- und Hals-Tumor
Mutationssignaturen beim Kopf- und Hals-Tumor: ZusammenfassungHintergrundDie Pathogenese beim Plattenepithelkarzinom der Kopf- und Halsregion (HNSCC, „head and neck squamous cell carcinoma“) ist ein komplexer Mehrstufenprozess und resultiert aus der Interaktion von exogenen und endogenen zellulären Prozessen. Jeder Prozess hinterlässt ein charakteristisches Muster an Mutationen auf dem Tumorgenom, eine sog. Tumorsignatur. StudienlageGegenstand aktueller Studien ist es, spezifische…

Medicine by Alexandros G.Sfakianakis

08:26

Frameless stereotactic radiosurgery
Performance assessment of two motion management systems for frameless stereotactic radiosurgery: AbstractBackground/PurposeFrameless stereotactic radiosurgery (SRS) requires dedicated systems to monitor patient motion in order to avoid inaccurate radiation delivery due to involuntary shifts. The purpose of this study is to assess the accuracy and sensitivity of two distinct motion monitoring systems used for frameless SRS. MethodsA surface image-guided system known as optical…

Medicine by Alexandros G.Sfakianakis

08:25

Custom designed radial forearm free flap for reconstruction of nasomaxillary defects: Report of two cases
Custom designed radial forearm free flap for reconstruction of nasomaxillary defects: Report of two cases: AbstractNasal amputation and nasomaxillary defects, need to reconstruct the internal lining, osteochondral structure, and external coating of the nose. Authors report a 70‐year‐old male and a 65‐year‐old female treated for nasomaxillary defects (Brown JS, Shaw RJ. The Lancet Oncology 2010;11:1001–1008) due to squamous cell carcinoma (SCC) where the tip of the nose was preserved. A new custom…

Medicine by Alexandros G.Sfakianakis

08:21

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Spindle Cell Melanoma Presenting as an Ulcer in a Diabetic
Spindle Cell Melanoma Presenting as an Ulcer in a Black Diabetic: Background. Melanoma in blacks is uncommon and exceedingly rare in association with a diabetic ulcer. We present a case of a spindle cell melanoma masquerading as a diabetic ulcer. Case Report. A 57-year-old overweight woman presented to The Maria Holder Diabetes Centre for the Caribbean with a nonhealing ulcer of the right heel after being treated by various primary care physicians over the preceding year. Her general and systematic…

Medicine by Alexandros G.Sfakianakis

08:20

Nummular Headache
Nummular Headache – a Case Report of a Rare Entity: Abstract Purpose of ReviewThe purpose of this manuscript is to shed light on systematic work-up of a diagnostic challenge such as nummular headache (NH), and to summarize the relevant literature on NH. Recent FindingsThe specific nature of the shape of the pain site is usually characteristic of NH. Multiple modalities of investigation including succinct imaging are necessary to successfully rule out other similar conditions. SummaryA 26-year-old…

Medicine by Alexandros G.Sfakianakis

08:19

Bleomycin sclerotherapy in lymphangiomas of the head and neck region: a prospective study
Bleomycin sclerotherapy in lymphangiomas of the head and neck region: a prospective study: Intralesional sclerotherapy for lymphatic malformations (LMs) has become a modality of choice because of the high morbidity and recurrence rates with surgical excision. Traditionally, the macrocystic variant has shown good results with sclerotherapy. This prospective study was performed to evaluate the role of bleomycin sclerotherapy in the management of different radiological variants of LM. A total of 142…

Medicine by Alexandros G.Sfakianakis

08:03

Adjuvant radiotherapy for endometrial cancer with cervical stromal involvement:
Adjuvant radiotherapy for endometrial cancer with cervical stromal involvement: A patterns of practice survey in Australia and New Zealand: AbstractIntroductionThe purpose of this study is to describe the patterns of practice in Australia and New Zealand for post‐operative radiotherapy in endometrial cancer with cervical stromal involvement.MethodsA ten‐item survey including five clinical case scenarios in endometrial cancer with cervical stromal invasion was emailed to Royal Australian and New Zealand…

Medicine by Alexandros G.Sfakianakis

08:03

DDGP vs. SMILE in Relapsed/Refractory Extranodal Natural Killer/T‐cell Lymphoma, Nasal Type
DDGP vs. SMILE in Relapsed/Refractory Extranodal Natural Killer/T‐cell Lymphoma, Nasal Type: A Retrospective Study of 54 Patients: Extranodal natural killer/T‐cell lymphoma, nasal type (ENKL) is a rare peripheral T‐cell lymphoma that predominantly occurs in Asian and South American populations. The treatment of ENKL has been a challenge for a long time. This study was conducted to compare the clinical efficacy and safety of cisplatin, dexamethasone, gemcitabine, and pegaspargase (DDGP) and methotrexate,…

Medicine by Alexandros G.Sfakianakis

08:02

Remimazolam in Procedural Sedation With Nonhomogeneously Mixed Arterial and Venous Concentrations
Population Pharmacokinetics of Remimazolam in Procedural Sedation With Nonhomogeneously Mixed Arterial and Venous Concentrations: Remimazolam is an ultra‐short acting benzodiazepine under development for procedural sedation and general anesthesia. Population pharmacokinetic analysis (PopPK) was conducted for remimazolam with arterial and venous samples previously, but results were limited by arterial‐venous concentration differences and inaccurate central volume of distribution (V1) estimates. A…

Medicine by Alexandros G.Sfakianakis

08:01

Evaluation of the Electroglottographic Signal Variability in Organic and Functional Dysphonia
Evaluation of the Electroglottographic Signal Variability in Organic and Functional Dysphonia: To confirm the data reported in our previous studies on the analysis of the variability of the electroglottographic signal in the pathological voice; to evaluate possible differences in variability between organic and functional pathologies; to identify any distinctive/typical EGG patterns for these pathologies.

Medicine by Alexandros G.Sfakianakis

07:59

Denosumab induced atypical fracture of free vascularized fibular graft 20 years after tumour reconstruction
Denosumab induced atypical fracture of free vascularized fibular graft 20 years after tumour reconstruction:

Medicine by Alexandros G.Sfakianakis

07:59

Renal cell carcinoma metastasis to the maxillary bone successfully treated with surgery after vascular embolization: a case report
Renal cell carcinoma metastasis to the maxillary bone successfully treated with surgery after vascular embolization: a case report: Metastasis of renal cell carcinoma to the oral cavity is rare. Renal cell carcinoma metastases are regarded as radioresistant tumors and surgery is recommended. However, since metastatic renal cell carcinoma h…

Medicine by Alexandros G.Sfakianakis

07:58

Driveline Infection with Vacuum-Assisted Closure Therapy and Instillation Therapy
Successful Treatment of Driveline Infection with Vacuum-Assisted Closure Therapy and Instillation Therapy: Thorac Cardiovasc Surg Rep 2020; 09: e29-e32DOI: 10.1055/s-0040-1713731Background Driveline infection is a serious complication in left ventricular assist device (LVAD) patients. We report the case of a patient who was successfully treated by combining instillation and vacuum-assisted closure (VAC) therapy. Case Description A 65-year-old LVAD patient presented with recurrent driveline…

Medicine by Alexandros G.Sfakianakis

07:58

Conservative Treatment of Iatrogenic Ascending Aortic Hematoma Post-Rotablator Coronary Procedure
Conservative Treatment of Iatrogenic Ascending Aortic Hematoma Post-Rotablator Coronary Procedure: Thorac Cardiovasc Surg Rep 2020; 09: e47-e50DOI: 10.1055/s-0040-1715431Background Aortic intramural hematoma due to coronary artery dissection is a rare and serious complication during percutaneous coronary intervention. Case Presentation A 78-year-old female patient was admitted for diagnostic coronarography in the context of stable angina. The coronarography showed an asymmetric and significate…

Medicine by Alexandros G.Sfakianakis

07:57

Genome-enabled inference of functional genetic variants in the face, brain and behavior [NEW RESULTS]
Genome-enabled inference of functional genetic variants in the face, brain and behavior [NEW RESULTS]: Lake Malawi cichlid fishes exhibit extensive divergence in form and function among closely related species separated by a relatively small number of genetic changes. During the past million years, hundreds of species have diversified along an ecological axis in rock vs. sand habitats. We compared the genomes of rock- and sand-dwelling species and asked which genetic variants in which genes differed…

Medicine by Alexandros G.Sfakianakis

07:56

The Effect of Pituitary Gland Disorders on Glucose Metabolism:
The Effect of Pituitary Gland Disorders on Glucose Metabolism: From Pathophysiology to Management: Horm Metab ResDOI: 10.1055/a-1258-8625This review aims to explore, present, and discuss disorders of glucose metabolism implicated in pituitary gland diseases, the appropriate interventions, as well as the therapeutic challenges that may arise. Pituitary pathologies may dysregulate glucose homeostasis, as both the excess and deficiency of various pituitary hormones can affect glucose metabolism. Increased…

Medicine by Alexandros G.Sfakianakis

07:55

Effect of periosteal reaction in medication-related osteonecrosis of the jaw on treatment outcome after surgery
Effect of periosteal reaction in medication-related osteonecrosis of the jaw on treatment outcome after surgery: AbstractIntroductionSurgical treatment in patients with medication-related osteonecrosis of the jaw (MRONJ) is superior to conservative treatment. However, treatment outcome in patients with periosteal reaction (PR) was significantly poorer than that of those without PR. The purpose of this retrospective study was to analyze the pathophysiology and clinical significance of PR in MRONJ….

Medicine by Alexandros G.Sfakianakis

07:52

A combined approach to correct posterior left ventricular aneurysm, aortic stenosis and coronary artery disease
A combined approach to correct posterior left ventricular aneurysm, aortic stenosis and coronary artery disease: AbstractIschaemic heart disease and aortic stenosis are potentially life-threatening conditions. A post-infarct left ventricular aneurysm, when combined with the above, is particularly hazardous. We present a case where all three conditions occurred simultaneously and describe the surgical approach undertaken to attempt correction. The patient underwent aneurysmectomy together with aortic…

Medicine by Alexandros G.Sfakianakis

07:51

Synonymous mutations and the molecular evolution of SARS-Cov-2 origins [NEW RESULTS]
Synonymous mutations and the molecular evolution of SARS-Cov-2 origins [NEW RESULTS]: Human severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is most closely related, by average genetic distance, to two coronaviruses isolated from bats, RaTG13 and RmYN02. However, there is a segment of high amino acid similarity between human SARS-CoV-2 and a pangolin isolated strain, GD410721, in the receptor binding domain (RBD) of the spike protein, a pattern that can be caused by either recombination…

Medicine by Alexandros G.Sfakianakis

07:51

Serial circulating tumor DNA in predicting and monitoring the effect of neoadjuvant chemoradiotherapy in patients with rectal cancer: a prospective multicenter study
Serial circulating tumor DNA in predicting and monitoring the effect of neoadjuvant chemoradiotherapy in patients with rectal cancer: a prospective multicenter study: Purpose: We investigated the value of circulating tumor DNA (ctDNA) in predicting tumor response to neoadjuvant chemoradiotherapy (nCRT), monitoring tumor burden, and prognosing survival in patients with locally advanced rectal cancer (LARC). Experimental Design: This prospective multicenter trial recruited 106 LARC patients for treatment…

Medicine by Alexandros G.Sfakianakis

07:50

Ramucirumab in Combination with Osimertinib in Advanced T790M-Positive EGFR-Mutant Non-Small Cell Lung Cancer
Phase 1 Study of the Efficacy and Safety of Ramucirumab in Combination with Osimertinib in Advanced T790M-Positive EGFR-Mutant Non-Small Cell Lung Cancer: Purpose: We report the final analysis of JVDL (NCT02789345), which examined the combination of the EGFR TKI osimertinib plus the VEGFR2-directed antibody ramucirumab in patients with T790M-positive EGFR-mutant NSCLC. Experimental Design: This open-label, single-arm phase 1 study enrolled patients with EGFR T790M-positive NSCLC, who had progressed…

Medicine by Alexandros G.Sfakianakis

07:48

Lysine-Specific Demethylase-1 Inhibitor CC-90011 in Patients With Advanced Solid Tumors and Relapsed/Refractory Non-Hodgkin Lymphoma
Phase I Study of Lysine-Specific Demethylase-1 Inhibitor CC-90011 in Patients With Advanced Solid Tumors and Relapsed/Refractory Non-Hodgkin Lymphoma: PURPOSE: Lysine-specific demethylase 1 (LSD1) is implicated in multiple tumor types and its expression in cancer stem cells is associated with chemoresistance. CC-90011 is a potent, selective, and reversible oral LSD1 inhibitor. We examined CC-90011 in advanced solid tumors and relapsed/refractory (R/R) non-Hodgkin lymphoma (NHL). EXPERIMENTAL DESIGN:…

Medicine by Alexandros G.Sfakianakis

07:47

Three distinct stroma types in human pancreatic cancer identified by image analysis of fibroblast subpopulations and collagen
Three distinct stroma types in human pancreatic cancer identified by image analysis of fibroblast subpopulations and collagen: Purpose: Cancer-associated fibroblasts have emerged to be highly heterogenous and can play multifaced roles in dictating pancreatic ductal adenocarcinoma (PDAC) progression, immunosuppression and therapeutic response, highlighting the need for a deeper understanding of stromal heterogeneity between patients and even within a single tumor. We hypothesized that image analysis…

Medicine by Alexandros G.Sfakianakis

07:47

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Activity and Safety of Geptanolimab (GB226) for patients with unresectable, recurrent or metastatic alveolar soft part sarcoma: a phase 2 single-arm study
Activity and Safety of Geptanolimab (GB226) for patients with unresectable, recurrent or metastatic alveolar soft part sarcoma: a phase 2 single-arm study: Purpose: Patients with alveolar soft part sarcoma (ASPS) are rare and have few treatment options. We assessed the activity of geptanolimab (GB226), a fully humanized PD-1 antibody, for patients with unresectable, recurrent or metastatic ASPS. Patients and methods: We did this multicentre, single-arm, phase 2 study (Gxplore-005,NCT03623581) in…

Medicine by Alexandros G.Sfakianakis

07:46

Intratumoral Injection of Clostridium novyi-NT Spores in Patients with Treatment-Refractory Advanced Solid Tumors
Intratumoral Injection of Clostridium novyi-NT Spores in Patients with Treatment-Refractory Advanced Solid Tumors: Purpose: Intratumorally injected Clostridium novyi-NT (non-toxic; lackingthe alpha toxin), an attenuated strain of C.novyi, replicates within hypoxic tumor regions resulting in tumor-confined cell lysis and inflammatory response in animals, which warrants clinical investigation. Experimental design: This first-in-humanstudy (NCT01924689) enrolled patients with injectable, treatment-refractory…

Medicine by Alexandros G.Sfakianakis

07:46

Preclinical activity of SAR408701, a novel anti-CEACAM5-maytansinoid antibody-drug conjugate for the treatment of CEACAM5-positive epithelial tumors
Preclinical activity of SAR408701, a novel anti-CEACAM5-maytansinoid antibody-drug conjugate for the treatment of CEACAM5-positive epithelial tumors: Purpose: Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) is a glycoprotein that has limited expression in normal adult tissues, but is overexpressed in carcinomas of the gastrointestinal tract, the genitourinary and respiratory systems, and breast cancer. As such, CEACAM5 is an attractive target for antibody-based therapies designed…

Medicine by Alexandros G.Sfakianakis

07:45

A cyclin D1-dependent transcriptional program predicts clinical outcome in mantle cell lymphoma
A cyclin D1-dependent transcriptional program predicts clinical outcome in mantle cell lymphoma: Purpose: Mantle cell lymphoma (MCL) is characterized by the t(11;14)(q13;q32) translocation leading to cyclin D1 overexpression. Cyclin D1 is a major cell cycle regulator and also regulates transcription, but the impact of cyclin D1-mediated transcriptional dysregulation on MCL pathogenesis remains poorly understood. The aim of this study was to define a cyclin D1-dependent gene expression program and…

Medicine by Alexandros G.Sfakianakis

07:44

A Morphometric Study of Stylomastoid Foramen with Its Clinical Applications
A Morphometric Study of Stylomastoid Foramen with Its Clinical Applications: J Neurol Surg B Skull BaseDOI: 10.1055/s-0040-1716674Background To prevent damage to the facial nerve while doing surgery and to give facial nerve block by anesthetics near the stylomastoid foramen we should know its distance from the important anatomical landmarks. So, this study aims to study the location of stylomastoid with respect to nearby anatomical landmarks. Materials and Method The study was performed…

Medicine by Alexandros G.Sfakianakis

07:42

The Longissimus Capitis Insertion as a Superficial Landmark for the Sigmoid Sinus: An Anatomical Study
The Longissimus Capitis Insertion as a Superficial Landmark for the Sigmoid Sinus: An Anatomical Study: J Neurol Surg B Skull BaseDOI: 10.1055/s-0040-1716890Objective Many external anatomical landmarks have been used for approximating deeper, intracranial structures. Herein, we evaluate the attachment of the longissimus capitis (LC) on the mastoid process as a landmark for the underlying sigmoid sinus. Methods Adult cadavers underwent dissection of the posterior occiput with special attention…

Medicine by Alexandros G.Sfakianakis

07:41

Advancement of PI3 Kinase Inhibitor Combination Therapies for PI3K-Aberrant Chordoma
Advancement of PI3 Kinase Inhibitor Combination Therapies for PI3K-Aberrant Chordoma: J Neurol Surg B Skull BaseDOI: 10.1055/s-0040-1716694Objectives Targeted inhibitors of the PI3 kinase (PI3K) pathway have shown promising but incomplete antitumor activity in preclinical chordoma models. The aim of this study is to advance methodology for a high-throughput drug screen using chordoma models to identify new combination therapies for chordoma. Study Design Present work is an in vitro study….

Medicine by Alexandros G.Sfakianakis

07:40

Preoperative Embolization on Juvenile Nasopharyngeal Angiofibroma
Effects of Preoperative Embolization on Juvenile Nasopharyngeal Angiofibroma Surgical Outcomes: A Study of the Kids’ Inpatient Database: J Neurol Surg B Skull BaseDOI: 10.1055/s-0040-1716676Objectives The aim of the study is to evaluate the effect of preoperative vascular embolization (PVE) on juvenile nasopharyngeal angiofibroma (JNA) surgical outcomes using a national pediatric hospitalization database. Methods The health care cost and utilization project Kids’ Inpatient Database was…

Medicine by Alexandros G.Sfakianakis

07:39

Management of Cutaneously Exposed Carotid Stents in Recurrent and Unresectable Head and Neck Cancer
Management of Cutaneously Exposed Carotid Stents in Recurrent and Unresectable Head and Neck Cancer: J Neurol Surg B Skull BaseDOI: 10.1055/s-0040-1716692Objective Carotid blowout syndrome (CBS) is a rare but potentially life-threatening complication of head and neck cancer (HNC) treatment. Patients with CBS are managed with covered stents, limited published information exists regarding the management of delayed complications, specifically cutaneous exposure of stents. Here, we present our experience…

Medicine by Alexandros G.Sfakianakis

07:38

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Neurocutaneous melanocytosis (melanosis)Abstract… pubmed: carotid blowout synd…Carotid blowout s… pubmed: gene therapies for h…GeneReviews®31mby… ScienceDirect Publication: BiomaterialsDesignin… Age based evaluation of nut aspiration riskTo id… Neurocutaneous melanocytosis (melanosis) What is dimethoate used for? Dimethoate is used to… Organophosphate Poisoning PDF Partial internal biliary diversion Biliary ascariasis and severe bacterial outcomes The Fussy Baby Network® (FBN), a program supportin… Birth Weight and the Development of Functional Gas… Low prevalence of infantile functional gastrointes… DNA repair targeted therapy Plants, Vol. 9, Pages 1350: Identification and An… Clinical GeneticsExploring genotype‐phenotype r… Intralesional methotrexate Intralesional immunotherapy for molluscum contagiosum Standardizing a volume benchmark for cerebrospinal… Adenomatous neuroendocrine tumors of the middle ea… Management of transmodiolar and transmacular cochl… Association of Estrogen Receptor 1 and Tumor Necro… Primary Intraosseous Squamous Cell Carcinoma Invol… Lymphocyte predominant Hodgkin lymphoma, antigen‐d… SETDB1 promotes gastric carcinogenesis and metasta… Microglia/macrophages express alternative proangio… Evaluation of myostatin as a possible regulator an… Effect of etelcalcetide on parathyroid hormone sec… The role of immune checkpoint inhibitor therapy in… Translational perspectives to treat Epidermolysis … Cantilevered resin-bonded fixed partial dentures Telomerase reverse transcriptase rs2736098 polymor… Cardiac contractility modulation attenuates struct… Imaging of bioluminescent Klebsiella pneumoniae in… Serum oestradiol levels are inversely associated w… Large (stage ≥T2b) and locally advanced renal cell… Risk factors for early postoperative recurrence in… Immune dysfunction in MGAT2‐CDG Cutaneous Manifestations in Adult Patients with CO… The Role of Environmental Exposures in Atopic Derm… Strategies for having a more effective and less to… Mutationssignaturen beim Kopf- und Hals-Tumor Frameless stereotactic radiosurgery Custom designed radial forearm free flap for recon… Spindle Cell Melanoma Presenting as an Ulcer in a … Nummular Headache Bleomycin sclerotherapy in lymphangiomas of the he… Adjuvant radiotherapy for endometrial cancer with … DDGP vs. SMILE in Relapsed/Refractory Extranodal N… Remimazolam in Procedural Sedation With Nonhomogen… Evaluation of the Electroglottographic Signal Vari… Denosumab induced atypical fracture of free vascul… Renal cell carcinoma metastasis to the maxillary b… Driveline Infection with Vacuum-Assisted Closure T… Conservative Treatment of Iatrogenic Ascending Aor… Genome-enabled inference of functional genetic var… The Effect of Pituitary Gland Disorders on Glucose… Effect of periosteal reaction in medication-relate… A combined approach to correct posterior left vent… Synonymous mutations and the molecular evolution o… Serial circulating tumor DNA in predicting and mon… Ramucirumab in Combination with Osimertinib in Adv… Lysine-Specific Demethylase-1 Inhibitor CC-90011 i… Three distinct stroma types in human pancreatic ca… Activity and Safety of Geptanolimab (GB226) for pa… Intratumoral Injection of Clostridium novyi-NT Spo… Preclinical activity of SAR408701, a novel anti-CE… A cyclin D1-dependent transcriptional program pred… A Morphometric Study of Stylomastoid Foramen with … The Longissimus Capitis Insertion as a Superficial… Advancement of PI3 Kinase Inhibitor Combination Th… Preoperative Embolization on Juvenile Nasopharynge… Management of Cutaneously Exposed Carotid Stents i… IntraOmmaya compartmental radioimmunotherapy using… Upper respiratory tract infectionHigh prevalenc… Behavioural Brain ResearchEffects of Childhood T… bioRxiv Subject Collection: Evolutionary Biolog… International Journal of Environmental Research… AntioxidantsAntioxidants, Vol. 9, Pages 978: Su…

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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia,

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Medicine by Alexandros G. Sfakianakis

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

Competency-Based Assessment Tool for Pediatric Esophagoscopy
Competency-Based Assessment Tool for Pediatric Esophagoscopy: International Modified Delphi Consensus.: Competency-Based Assessment Tool for Pediatric Esophagoscopy: International Modified Delphi Consensus.Laryngoscope. 2020 Oct 09;:Authors: Faucett EA, Wolter NE, Balakrishnan K, Ishman SL, Mehta D, Parikh S, Nguyen LHP, Preciado D, Rutter MJ, Prager JD, Green GE, Pransky SM, Elluru R, Husein M, Roy S, Johnson KE, Friedberg J, Johnson RF, Bauman NM, Myer CM, Deutsch ES, Gantwerker EA, Willging JP,…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:26

Effect of Fluorescence Visualization-Guided Surgery on Local Recurrence of Oral Squamous Cell Carcinoma
Effect of Fluorescence Visualization-Guided Surgery on Local Recurrence of Oral Squamous Cell Carcinoma: A Randomized Clinical Trial.: Effect of Fluorescence Visualization-Guided Surgery on Local Recurrence of Oral Squamous Cell Carcinoma: A Randomized Clinical Trial.JAMA Otolaryngol Head Neck Surg. 2020 Oct 08;:Authors: Durham JS, Brasher P, Anderson DW, Yoo J, Hart R, Dort JC, Seikaly H, Kerr P, Rosin MP, Poh CFAbstract Importance: High local recurrence rates with aggressive disease remain…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:25

Incorporating dose-volume histogram parameters of swallowing organs at risk in a videofluoroscopy-based predictive model of radiation-induced dysphagia after head and neck cancer intensity-modulated radiation therapy.
Incorporating dose-volume histogram parameters of swallowing organs at risk in a videofluoroscopy-based predictive model of radiation-induced dysphagia after head and neck cancer intensity-modulated radiation therapy.: Incorporating dose-volume histogram parameters of swallowing organs at risk in a videofluoroscopy-based predictive model of radiation-induced dysphagia after head and neck cancer intensity-modulated radiation therapy.Strahlenther Onkol. 2020 Oct 09;:Authors: Ursino S, Giuliano A,…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:25

The prostate-specific membrane antigen (PSMA)-targeted radiotracer 18F-DCFPyL detects tumor neovasculature in metastatic, advanced, radioiodine-refractory, differentiated thyroid cancer.
The prostate-specific membrane antigen (PSMA)-targeted radiotracer 18F-DCFPyL detects tumor neovasculature in metastatic, advanced, radioiodine-refractory, differentiated thyroid cancer.: The prostate-specific membrane antigen (PSMA)-targeted radiotracer 18F-DCFPyL detects tumor neovasculature in metastatic, advanced, radioiodine-refractory, differentiated thyroid cancer.Med Oncol. 2020 Oct 09;37(11):98Authors: Santhanam P, Russell J, Rooper LM, Ladenson PW, Pomper MG, Rowe SPAbstract Prostate-specific…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:24

Pilot study of loss of the p53/p63 target gene PERP at the surgical margin as a potential predictor of local relapse in head and neck squamous cell carcinoma.
Pilot study of loss of the p53/p63 target gene PERP at the surgical margin as a potential predictor of local relapse in head and neck squamous cell carcinoma.: Pilot study of loss of the p53/p63 target gene PERP at the surgical margin as a potential predictor of local relapse in head and neck squamous cell carcinoma.Head Neck. 2020 Jul 07;:Authors: Holmes BJ, von Eyben R, Attardi LD, Kong CS, Le QT, Nathan COAbstract BACKGROUND: PERP (p53 apoptosis effector related to PMP22) localizes to…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:24

Nonepithelial Tumors of the Larynx
Nonepithelial Tumors of the Larynx: Single-Institution 13-Year Review with Radiologic-Pathologic Correlation.: Nonepithelial Tumors of the Larynx: Single-Institution 13-Year Review with Radiologic-Pathologic Correlation.Radiographics. 2020 Oct 09;:190210Authors: Ong AC, Huh EH, Moreland AJ, Rooper LM, Aygun N, Akst LM, Best SR, Khan MAAbstract Nonepithelial tumors of the larynx are rare and represent a minority of all laryngeal neoplasms. Imaging has an important role in the diagnosis,…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:23

Bilateral "Rescue Strip" Technique for Endoscopic Endonasal Approaches to the Clivus.
Bilateral "Rescue Strip" Technique for Endoscopic Endonasal Approaches to the Clivus.: Bilateral "Rescue Strip" Technique for Endoscopic Endonasal Approaches to the Clivus.Oper Neurosurg (Hagerstown). 2020 Oct 09;:Authors: Kim M, Otten M, Overdevest JB, Gudis DAAbstract BACKGROUND: The vascularized nasoseptal flap (NSF) is a pillar of contemporary endoscopic skull base reconstruction. The pedicle for the NSF is supplied by the posterior septal branch of the sphenopalatine artery, which…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:23

Ultrasonography on the Early Postoperative Control of Severe Odontogenic Infections.
Ultrasonography on the Early Postoperative Control of Severe Odontogenic Infections.: Ultrasonography on the Early Postoperative Control of Severe Odontogenic Infections.J Oral Maxillofac Surg. 2020 Sep 11;:Authors: Costa SM, Silveira RL, Amaral MBFAbstract The management of odontogenic infections remains an important segment of the oral-maxillofacial surgical practice. The implementation of ultrasonography (US) imaging for the diagnosis of head and neck infections increases the possibility…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:22

The use of a MITO-Porter to deliver exogenous therapeutic RNA to a mitochondrial disease’s cell with a A1555G mutation in the mitochondrial 12S rRNA gene results in an increase in mitochondrial respiratory activity.
The use of a MITO-Porter to deliver exogenous therapeutic RNA to a mitochondrial disease’s cell with a A1555G mutation in the mitochondrial 12S rRNA gene results in an increase in mitochondrial respiratory activity.: The use of a MITO-Porter to deliver exogenous therapeutic RNA to a mitochondrial disease’s cell with a A1555G mutation in the mitochondrial 12S rRNA gene results in an increase in mitochondrial respiratory activity.Mitochondrion. 2020 Oct 06;:Authors: Yamada Y, Maruyama M, Kita T, Usami…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:22

Neurovascular complications …Pulmonary embolisms, deep vein thrombosis, and arterial thrombosis of the abdominal small vessels,arterial and venous thrombosis pertaining to the head and neck
Neurovascular complications that can be seen in COVID-19 patients.: Neurovascular complications that can be seen in COVID-19 patients.Clin Imaging. 2020 Oct 06;69:280-284Authors: Kihira S, Schefflein J, Pawha P, Rigney B, Delman BN, Xuan D, Fifi J, Doshi AH, Belani PAbstract Coronavirus disease 2019 (COVID-19), a clinical manifestation of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), was declared a global pandemic by the World Health Organization on March 11, 2020. Hypercoagulable…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:21

Monte Carlo calculations of radiotherapy dose in "homogeneous" anatomy.
Monte Carlo calculations of radiotherapy dose in "homogeneous" anatomy.: Monte Carlo calculations of radiotherapy dose in "homogeneous" anatomy.Phys Med. 2020 Oct 06;78:156-165Authors: Kairn T, Livingstone AG, Crowe SBAbstract Given the substantial literature on the use of Monte Carlo (MC) simulations to verify treatment planning system (TPS) calculations of radiotherapy dose in heterogeneous regions, such as head and neck and lung, this study investigated the potential value of running…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:21

Fibrous Dysplasia, Paget’s Disease of Bone, and Other Uncommon Sclerotic Bone Lesions of the Craniofacial Bones.
Fibrous Dysplasia, Paget’s Disease of Bone, and Other Uncommon Sclerotic Bone Lesions of the Craniofacial Bones.: Fibrous Dysplasia, Paget’s Disease of Bone, and Other Uncommon Sclerotic Bone Lesions of the Craniofacial Bones.Semin Musculoskelet Radiol. 2020 Oct;24(5):570-578Authors: Van de Voorde N, Mortier GR, Vanhoenacker FMAbstract Imaging studies of the brain, head and neck, sinuses, and dental computed tomography are among the most frequently performed procedures in radiologic departments….

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:20

Impact of exercise with TheraBite device on trismus
Impact of exercise with TheraBite device on trismus and health-related quality of life: A prospective study.: Impact of exercise with TheraBite device on trismus and health-related quality of life: A prospective study.Ear Nose Throat J. 2020 Oct 09;:145561320961727Authors: Montalvo C, Finizia C, Pauli N, Fagerberg-Mohlin B, Andréll PAbstract Trismus is a common symptom in patients with head and neck cancer that affects many aspects of daily life negatively. The aim of this study was to…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:20

The Role of Tracheotomy and Timing of Weaning and Decannulation in Patients Affected by Severe COVID-19.
The Role of Tracheotomy and Timing of Weaning and Decannulation in Patients Affected by Severe COVID-19.: The Role of Tracheotomy and Timing of Weaning and Decannulation in Patients Affected by Severe COVID-19.Ear Nose Throat J. 2020 Oct 09;:145561320965196Authors: Botti C, Lusetti F, Peroni S, Neri T, Castellucci A, Salsi P, Ghidini AAbstract OBJECTIVES: Patients with acute respiratory failure due to coronavirus disease 2019 (COVID-19) have a high likelihood of needing prolonged intubation…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:19

Perilymphatic Fistula Manifesting as a Pseudomeningocele-Like Presentation Following Stapedectomy.
Perilymphatic Fistula Manifesting as a Pseudomeningocele-Like Presentation Following Stapedectomy.: Perilymphatic Fistula Manifesting as a Pseudomeningocele-Like Presentation Following Stapedectomy.Ear Nose Throat J. 2020 Oct 09;:145561320965200Authors: Ashman PE, Jyung RWPMID: 33035130 [PubMed – as supplied by publisher]

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:19

Skull Base Metastasis of Breast Cancer With Oculomotor and Trochlear Nerve Palsy.
Skull Base Metastasis of Breast Cancer With Oculomotor and Trochlear Nerve Palsy.: Skull Base Metastasis of Breast Cancer With Oculomotor and Trochlear Nerve Palsy.Ear Nose Throat J. 2020 Oct 09;:145561320963676Authors: Adachi K, Maeda Y, Hayama M, Kitaguchi Y, Nojima S, Nitta K, Obata S, Nakatani A, Tsuda T, Takeda K, Morii E, Inohara HAbstract Skull base metastatic tumors are rare. Breast cancer in particular can cause bone metastases after a long period of time. A 70-year-old woman presented…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:19

Biologics in Chronic Rhinosinusitis With Nasal Polyps.
The Role of Biologics in Chronic Rhinosinusitis With Nasal Polyps.: The Role of Biologics in Chronic Rhinosinusitis With Nasal Polyps.Ear Nose Throat J. 2020 Oct 09;:145561320964653Authors: Patel GB, Peters ATAbstract Biologic therapy is a new treatment option for patients with chronic rhinosinusitis with nasal polyps (CRSwNP). Currently, the only biologic with Food and Drug Administration-approval status for CRSwNP is dupilumab. Several other biologics are likely to be approved for CRSwNP,…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:18

Laryngeal Blastomycosis
Laryngeal Blastomycosis, an Unexpected Diagnosis: A Case Report.: Laryngeal Blastomycosis, an Unexpected Diagnosis: A Case Report.J Voice. 2020 Oct 05;:Authors: Ballestas SA, Magliocca KR, Balter L, Hatcher JLAbstract Isolated laryngeal blastomycosis is an extremely rare entity with few cases described in the medical literature. Nonspecific and chronic presenting symptoms such as dysphonia, dyspnea, dysphagia, and/or cough are described, with isolated reports requiring urgent management…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:18

Voice-Related Quality of Life, Anxiety, and Depression in Female Teachers
Voice-Related Quality of Life, Anxiety, and Depression in Female Teachers: Finger Kazoo Intensive Short-Term Vocal Therapy.: Voice-Related Quality of Life, Anxiety, and Depression in Female Teachers: Finger Kazoo Intensive Short-Term Vocal Therapy.J Voice. 2020 Oct 05;:Authors: Christmann MK, Scapini F, Lima JPM, Gonçalves BFDT, Bastilha GR, Cielo CAAbstract BACKGROUND: Among professional voice users, teachers are subject to higher risks of developing occupational dysphonia due to their…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:17

Maturity-onset diabetes of the young, or MODY-monogenic diabetes
Approach to the Patient with MODY-Monogenic Diabetes.: Approach to the Patient with MODY-Monogenic Diabetes.J Clin Endocrinol Metab. 2020 Oct 09;:Authors: Broome DT, Pantalone KM, Kashyap S, Philipson LHAbstract Maturity-onset diabetes of the young, or MODY-monogenic diabetes, is a not-so-rare collection of inherited disorders of non-autoimmune diabetes mellitus that remains insufficiently diagnosed despite increasing awareness. These diagnoses are important to efficiently and accurately…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:16

Serum Irisin Levels in Central Precocious Puberty and Its Variants.
Serum Irisin Levels in Central Precocious Puberty and Its Variants.: Serum Irisin Levels in Central Precocious Puberty and Its Variants.J Clin Endocrinol Metab. 2020 Oct 09;:Authors: Kutlu E, Özgen İT, Bulut H, Koçyiğit A, Otçu H, Cesur YAbstract AIM: The exact mechanisms that trigger the onset of puberty are not well known. Adipomyokines are postulated to stimulate the central neural network. In the present study, we investigated irisin levels in girls with central precocious puberty (CPP),…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:15

Interactions of anemia, FGF-23 and bone in healthy adults
Interactions of anemia, FGF-23 and bone in healthy adults – results from the Study of Health in Pomerania (SHIP).: Interactions of anemia, FGF-23 and bone in healthy adults – results from the Study of Health in Pomerania (SHIP).J Clin Endocrinol Metab. 2020 Oct 09;:Authors: Hannemann A, Nauck M, Völzke H, Weidner H, Platzbecker U, Hofbauer LC, Rauner M, Baschant UAbstract CONTEXT: Osteoporosis and anemia are amongst the most common diseases in the aging population with a worldwide increasing…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:15

Factors Associated with Decline of C-peptide in a Cohort of Young Children Diagnosed with Type 1 Diabetes.
Factors Associated with Decline of C-peptide in a Cohort of Young Children Diagnosed with Type 1 Diabetes.: Factors Associated with Decline of C-peptide in a Cohort of Young Children Diagnosed with Type 1 Diabetes.J Clin Endocrinol Metab. 2020 Oct 09;:Authors: Steck AK, Liu X, Krischer JP, Haller MJ, Veijola R, Lundgren M, Ahmed S, Akolkar B, Toppari J, Hagopian WA, Rewers MJ, Elding Larsson HAbstract CONTEXT: Understanding factors involved in the rate of C-peptide decline is needed to tailor…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:14

Angiotensin-Converting Enzyme Inhibitors Reduce Uterine Fibroid Incidence in Hypertensive Women.
Angiotensin-Converting Enzyme Inhibitors Reduce Uterine Fibroid Incidence in Hypertensive Women.: Angiotensin-Converting Enzyme Inhibitors Reduce Uterine Fibroid Incidence in Hypertensive Women.J Clin Endocrinol Metab. 2020 Oct 09;:Authors: Fischer NM, Nieuwenhuis TO, Singh B, Yenokyan G, Segars JHAbstract CONTEXT: In-vitro and in-vivo evidence has supported the role of angiotensin II blockade in reducing leiomyoma cell proliferation and growth. However, no population-based study to date…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:14

CDK 4/6 Inhibition Overcomes Acquired and Inherent Resistance to PI3Kα Inhibition in Pre-Clinical Models of Head and Neck Squamous Cell Carcinoma.
CDK 4/6 Inhibition Overcomes Acquired and Inherent Resistance to PI3Kα Inhibition in Pre-Clinical Models of Head and Neck Squamous Cell Carcinoma.: CDK 4/6 Inhibition Overcomes Acquired and Inherent Resistance to PI3Kα Inhibition in Pre-Clinical Models of Head and Neck Squamous Cell Carcinoma.J Clin Med. 2020 Oct 07;9(10):Authors: Remer E, Badarni M, Hikri E, Dayan A, Levi L, Popovtzer A, Iraqi M, Porgador A, Joshua BZ, Bachar G, Elkabets M, Scaltriti M, Mizrachi AAbstract Activating alterations…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:13

Regulation of NFκB Signalling by Ubiquitination: A Potential Therapeutic Target in Head and Neck Squamous Cell Carcinoma?
Regulation of NFκB Signalling by Ubiquitination: A Potential Therapeutic Target in Head and Neck Squamous Cell Carcinoma?: Regulation of NFκB Signalling by Ubiquitination: A Potential Therapeutic Target in Head and Neck Squamous Cell Carcinoma?Cancers (Basel). 2020 Oct 07;12(10):Authors: Morgan EL, Chen Z, Van Waes CAbstract Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide, with over 600,000 cases per year. The primary causes for HNSCC include smoking…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:13

Clinical Veterinary Boron Neutron Capture Therapy (BNCT) Studies in Dogs with Head and Neck Cancer: Bridging the Gap between Translational and Clinical Studies.
Clinical Veterinary Boron Neutron Capture Therapy (BNCT) Studies in Dogs with Head and Neck Cancer: Bridging the Gap between Translational and Clinical Studies.: Clinical Veterinary Boron Neutron Capture Therapy (BNCT) Studies in Dogs with Head and Neck Cancer: Bridging the Gap between Translational and Clinical Studies.Biology (Basel). 2020 Oct 07;9(10):Authors: Schwint AE, Monti Hughes A, Garabalino MA, Santa Cruz GA, González SJ, Longhino J, Provenzano L, Oña P, Rao M, Cantarelli MLÁ, Leiras…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:13

Artificial Neural Network as a Tool to Predict Facial Nerve Palsy in Parotid Gland Surgery for Benign Tumors.
Artificial Neural Network as a Tool to Predict Facial Nerve Palsy in Parotid Gland Surgery for Benign Tumors.: Artificial Neural Network as a Tool to Predict Facial Nerve Palsy in Parotid Gland Surgery for Benign Tumors.Med Sci (Basel). 2020 Oct 07;8(4):Authors: Chiesa-Estomba CM, Sistiaga-Suarez JA, González-García JÁ, Larruscain E, Cammaroto G, Mayo-Yánez M, Lechien JR, Calvo-Henríquez C, Altuna X, Medela AAbstract (1) Background: Despite the increasing use of intraoperative facial nerve…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:12

Protection of nerve function during transoral endoscopic thyroidectomy by vestibular approach].
[Protection of nerve function during transoral endoscopic thyroidectomy by vestibular approach].: [Protection of nerve function during transoral endoscopic thyroidectomy by vestibular approach].Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Oct 07;55(10):893-898Authors: Wu Z, Fang JG, Chen X, Hou LZ, Zhong Q, Ma HZ, Zhang Y, Shen XXAbstract Objective: To explore the method of functional protection in transoral endoscopic thyroidectomy by vestibular approach. Methods: Retrospective…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:12

Gasless unilateral axillary approach (GUAA) in endoscopic thyroid surgery
[Clinical application of the gasless unilateral axillary approach in endoscopic thyroid surgery].: [Clinical application of the gasless unilateral axillary approach in endoscopic thyroid surgery].Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Oct 07;55(10):913-920Authors: Xu JJ, Zhang LZ, Zhang QH, Guo HW, Tan Z, Wang JF, Jiang LH, Zheng CM, Ge MH, Lan XBAbstract Objective: To investigate the efficacy, safety and advantages of gasless unilateral axillary approach (GUAA) in endoscopic…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:12

Long non-coding RNA colon cancer associated transcript-2 from nasopharyngeal carcinoma-derived exosomes promotes angiogenesis].
[Long non-coding RNA colon cancer associated transcript-2 from nasopharyngeal carcinoma-derived exosomes promotes angiogenesis].: [Long non-coding RNA colon cancer associated transcript-2 from nasopharyngeal carcinoma-derived exosomes promotes angiogenesis].Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Oct 07;55(10):944-951Authors: Zhou SK, Gao F, Zhong ZS, Yao HAbstract Objective: To evaluate the role of exosomal long non-coding RNA (lncRNA) colon cancer associated transcript-2(CCAT2)…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:11

Robot-assisted electrode insertion in cochlear implantation].
[Preliminary application of robot-assisted electrode insertion in cochlear implantation].: [Preliminary application of robot-assisted electrode insertion in cochlear implantation].Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Oct 07;55(10):952-956Authors: Jia H, Pan JX, Li Y, Zhang ZH, Tan HY, Wang ZY, Wu HAbstract Objective: To evaluate the safety and outcomes of robot-assisted electrode insertion in cochlear implantation. Methods: We first reported the case of robot-assisted electrode…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:11

Tap-hammer elicited vestibular-evoked myogenic potentials system: its design and preliminary application].
[Tap-hammer elicited vestibular-evoked myogenic potentials system: its design and preliminary application].: [Tap-hammer elicited vestibular-evoked myogenic potentials system: its design and preliminary application].Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Oct 07;55(10):957-961Authors: Zhang YZ, Xiong P, Zhao HD, Chen ZC, Wei XY, Liu Q, Chen FY, Cheng Y, Hu J, Li SN, Yang J, Zhang QAbstract Objective: The aim of this study was to design and perform "Tap-hammer"system that can…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:10

Concomitant cemento-osseous dysplasia and aneurysmal bone cyst of the mandible
Concomitant cemento-osseous dysplasia and aneurysmal bone cyst of the mandible: a rare case report with literature review.: Concomitant cemento-osseous dysplasia and aneurysmal bone cyst of the mandible: a rare case report with literature review.BMC Oral Health. 2020 Oct 09;20(1):276Authors: Yeom HG, Yoon JHAbstract BACKGROUND: Concomitant cemento-osseous dysplasia (COD) and aneurysmal bone cyst (ABC) are rare in the head and neck region. In our search of the English language literature,…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:10

Age based evaluation of nut aspiration risk.
Age based evaluation of nut aspiration risk.: Age based evaluation of nut aspiration risk.J Otolaryngol Head Neck Surg. 2020 Oct 09;49(1):73Authors: D’Souza JN, Valika TS, Bhushan B, Ida JBAbstract OBJECTIVE: To identify an age at which initiation of whole nut into the pediatric diet could be considered safe, by evaluating the age distribution of children undergoing bronchoscopy with removal of nut or seed material from the airway. METHOD: A retrospective chart review over a ten-year…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:08

Epigenetic regulation of VENTXP1 suppresses tumor proliferation via miR-205-5p/ANKRD2/NF-kB signaling in head and neck squamous cell carcinoma.
Epigenetic regulation of VENTXP1 suppresses tumor proliferation via miR-205-5p/ANKRD2/NF-kB signaling in head and neck squamous cell carcinoma.: Epigenetic regulation of VENTXP1 suppresses tumor proliferation via miR-205-5p/ANKRD2/NF-kB signaling in head and neck squamous cell carcinoma.Cell Death Dis. 2020 Oct 09;11(10):838Authors: Zhang LM, Su LX, Hu JZ, Wang M, Ju HY, Li X, Han YF, Xia WY, Guo W, Ren GX, Fan XDAbstract An increasing number of studies have shown that long noncoding RNAs…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:08

TrkA inhibitor promotes motor functional regeneration of recurrent laryngeal nerve by suppression of sensory nerve regeneration.
TrkA inhibitor promotes motor functional regeneration of recurrent laryngeal nerve by suppression of sensory nerve regeneration.: TrkA inhibitor promotes motor functional regeneration of recurrent laryngeal nerve by suppression of sensory nerve regeneration.Sci Rep. 2020 Oct 09;10(1):16892Authors: Suzuki H, Araki K, Matsui T, Tanaka Y, Uno K, Tomifuji M, Yamashita T, Satoh Y, Kobayashi Y, Shiotani AAbstract Recurrent laryngeal nerve (RLN) injury, in which hoarseness and dysphagia arise…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:07

Modified submental platysmal adipomyofascial flap
Modified submental platysmal adipomyofascial flap: is it a reliable alternate reconstructive option for small- to mid-sized defects especially in male patients with oral/oropharyngeal cancer?: Modified submental platysmal adipomyofascial flap: is it a reliable alternate reconstructive option for small- to mid-sized defects especially in male patients with oral/oropharyngeal cancer?Eur Arch Otorhinolaryngol. 2020 Oct 09;:Authors: Singh A, Chopra A, Chaudhary S, Venkatasubramaniyan M, Joshi K, Agarwal…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:07

Manganese, Cadmium, Chromium and Selenium levels could play an important role in etio-pathogenesis of tinnitus, and thereby supplementation or reduction of these elements could be considered as novel therapeutic goals.
The Role of Manganese, Cadmium, Chromium and Selenium on Subjective Tinnitus.: The Role of Manganese, Cadmium, Chromium and Selenium on Subjective Tinnitus.Biol Trace Elem Res. 2020 Oct 09;:Authors: Atila NE, Atila A, Kaya Z, Bulut YE, Oner F, Topal K, Bayraktutan Z, Bakan EAbstract Elevated levels of heavy metals like cadmium (Cd) and manganese (Mn) are known to lead to oxidative damage-related oto-toxicity and decreased levels of chromium (Cr) and selenium (Se) are known to lead to oto-toxicity…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:06

Αφαίρεση διαφημίσεων


Reconstructive Options During Nonfunctional Laryngectomy.
Reconstructive Options During Nonfunctional Laryngectomy.: Reconstructive Options During Nonfunctional Laryngectomy.Laryngoscope. 2020 Oct 10;:Authors: Escalante D, Vincent AG, Wang W, Shokri T, Ducic YAbstract OBJECTIVE: A paucity of data exists regarding surgical outcomes for patients undergoing total laryngectomy for a dysfunctional larynx. Herein, we present the largest study evaluating the method of closure on postoperative fistula rate and swallowing ability. METHOD: We performed…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:04

Peri-procedural Anticoagulation in Patients with Head and Neck Versus Extremity Venous Malformations.
Peri-procedural Anticoagulation in Patients with Head and Neck Versus Extremity Venous Malformations.: Peri-procedural Anticoagulation in Patients with Head and Neck Versus Extremity Venous Malformations.Laryngoscope. 2020 Oct 10;:Authors: Dharmarajan H, McCoy JL, Jabbour N, McCormick A, Xavier F, Correa D, Padia RAbstract OBJECTIVE: (1) Review a multidisciplinary vascular anomalies center’s practice regarding periprocedural anticoagulation for venous malformations (VM) and the associated…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:04

Neuromodulators for Atypical Facial Pain and Neuralgias
Neuromodulators for Atypical Facial Pain and Neuralgias: A Systematic Review and Meta-Analysis.: Neuromodulators for Atypical Facial Pain and Neuralgias: A Systematic Review and Meta-Analysis.Laryngoscope. 2020 Oct 10;:Authors: Do TM, Unis GD, Kattar N, Ananth A, McCoul EDAbstract OBJECTIVE: To evaluate the effectiveness of neuromodulating agents for the management of atypical facial pain and primary facial neuralgias. METHODS: We searched MEDLINE, Embase, CINAHL, and ClinicalTrials.gov…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:04

Anatomic Danger Zones of the Head and Neck….on branches of the facial nerve, parotid duct, spinal accessory nerve, trigeminal nerve, and the lacrimal system.
Anatomic Danger Zones of the Head and Neck.: Anatomic Danger Zones of the Head and Neck.Dermatol Surg. 2020 Oct 02;:Authors: Talmor G, Trang A, Ahadiat O, Paskhover B, Wysong AAbstract BACKGROUND: Dermatologic procedures require a detailed understanding of surface anatomy to avoid complications. The head and neck region has prominent danger zones including nerves and vasculature that may be at risk during cutaneous surgery. A thorough understanding of these danger zones can help avoid complications…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:04

The Anatomy of the Temporal and Zygomatic Branches of the Facial Nerve: Application to Crow’s Feet Wrinkles.
The Anatomy of the Temporal and Zygomatic Branches of the Facial Nerve: Application to Crow’s Feet Wrinkles.: The Anatomy of the Temporal and Zygomatic Branches of the Facial Nerve: Application to Crow’s Feet Wrinkles.J Craniofac Surg. 2020 Oct 08;:Authors: Ye P, Feng XL, Yang ZH, Li GP, Sun J, Wu HX, Chen SCAbstract BACKGROUND: Advances in the understanding of wrinkling crow’s feet while improving the safety and efficacy of botulinum toxin type A injection has pointed to drug dispersion…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:02

Reinforced-hydrogel encapsulated hMSCs towards brain injury treatment by trans-septal approach.
Reinforced-hydrogel encapsulated hMSCs towards brain injury treatment by trans-septal approach.: Reinforced-hydrogel encapsulated hMSCs towards brain injury treatment by trans-septal approach.Biomaterials. 2020 Sep 30;266:120413Authors: Sultan MT, Choi BY, Ajiteru O, Hong DK, Lee SM, Kim HJ, Ryu JS, Lee JS, Hong H, Lee YJ, Lee H, Suh YJ, Lee OJ, Kim SH, Suh SW, Park CHAbstract Encapsulated stem cells in various biomaterials have become a potentially promising cell transplantation strategy…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:02

Annual malignant transformation rate of oral leukoplakia remains consistent: A long-term follow-up study.
Annual malignant transformation rate of oral leukoplakia remains consistent: A long-term follow-up study.: Annual malignant transformation rate of oral leukoplakia remains consistent: A long-term follow-up study.Oral Oncol. 2020 Oct 07;110:105014Authors: Evren I, Brouns ER, Wils LJ, Poell JB, Peeters CFW, Brakenhoff RH, Bloemena E, de Visscher JGAMAbstract OBJECTIVES: Numerous clinical and histopathological characteristics have been associated with malignant transformation (MT) of oral…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:01

Impact of histological Oral Tongue Cancer margins on locoregional recurrence: A multi-centre retrospective analysis.
Impact of histological Oral Tongue Cancer margins on locoregional recurrence: A multi-centre retrospective analysis.: Impact of histological Oral Tongue Cancer margins on locoregional recurrence: A multi-centre retrospective analysis.Oral Oncol. 2020 Oct 07;111:105004Authors: Daniell J, Udovicich C, Rowe D, McDowell L, Vital D, Bressel M, Magarey MJR, Iseli TA, Wong T, Lekgabe E, Cavanagh K, Fua T, Rischin D, Wiesenfeld DAbstract OBJECTIVES: To assess the effect of the histological margins…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:01

Locoregional and distant recurrence for HPV-associated oropharyngeal cancer using AJCC 8 staging.
Locoregional and distant recurrence for HPV-associated oropharyngeal cancer using AJCC 8 staging.: Locoregional and distant recurrence for HPV-associated oropharyngeal cancer using AJCC 8 staging.Oral Oncol. 2020 Oct 07;111:105030Authors: Contrera KJ, Smile TD, Mahomva C, Wei W, Adelstein DJ, Broughman JR, Burkey BB, Geiger JL, Joshi NP, Ku JA, Lamarre ED, Lorenz RR, Prendes BL, Scharpf J, Schwartzman LM, Woody NM, Xiong D, Koyfman SAAbstract INTRODUCTION: The objective of this study is…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:01

Chamomile extract is effective in further reducing the clinical symptoms and improving the quality of life of chronic rhinosinusitis
Effects of chamomile extract nasal drop on chronic rhinosinusitis treatment: A randomized double blind study.: Effects of chamomile extract nasal drop on chronic rhinosinusitis treatment: A randomized double blind study.Am J Otolaryngol. 2020 Sep 28;42(1):102743Authors: Nemati S, Yousefbeyk F, Ebrahimi SM, FaghihHabibi AF, Shakiba M, Ramezani HAbstract OBJECTIVES: Recently, more attention has been paid to herbal treatment in chronic rhinosinusitis (CRS) patients. Chamomile (Matrricaria…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:00

A rare case of cystic hygroma in neck and extending into thoracic cavity.
A rare case of cystic hygroma in neck and extending into thoracic cavity.: A rare case of cystic hygroma in neck and extending into thoracic cavity.Int J Surg Case Rep. 2020 Oct 03;76:174-177Authors: El Sayed M, Touny M, Ibrahim N, Kasb I, Al-Azzawi ZAbstract INTRODUCTION: Cystic hygroma is a benign swelling of the neck among the pediatric population. It is a fluid-filled sac resulting from blockage in the lymphatic system and is commonly located in the cervical region and axilla. …

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:00

Teacher training as a means to sustained and multiplicative behavior change: An example using fuel‐efficient stoves
Teacher training as a means to sustained and multiplicative behavior change: An example using fuel‐efficient stoves: Graphical abstractTeacher training was provided on how to build fuell‐efficient stoves, which reduce need for fuel.Paper found sustained behavior change with community building up to 150 stoves per year even three years after initial training.Paper found consistent improvement in knowledge from beginning to end of school year in relation to fuel‐efficient stoves up to two years after…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:58

Magnetic resonance imaging features and prognosis of invasive pituitary adenoma].
[Analysis of correlation between magnetic resonance imaging features and prognosis of invasive pituitary adenoma].: [Analysis of correlation between magnetic resonance imaging features and prognosis of invasive pituitary adenoma].Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Oct 07;55(10):926-933Authors: Liu H, Zhang Q, Hang W, Liu GAbstract Objective: To explore the application of conventional nuclear magnetic resonance imaging, diffusion-weighted imaging and dynamic contrast-enhanced…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:58

SIRT1 on promoting the proliferation, migration and lipid metabolism of nasopharyngeal carcinoma].
[Research of SIRT1 on promoting the proliferation, migration and lipid metabolism of nasopharyngeal carcinoma].: [Research of SIRT1 on promoting the proliferation, migration and lipid metabolism of nasopharyngeal carcinoma].Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Oct 07;55(10):934-943Authors: Yin HM, He X, Shan Y, Zhai HX, Zhang KW, Xia T, Zhang SY, Chen WH, You YWAbstract Objective: To analyze the differential expression of silent information regulator transcript-1 (SIRT1) in…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:57

Dysphonia and dysphagia as early manifestations of autoimmune inflammatory myopathy.
Dysphonia and dysphagia as early manifestations of autoimmune inflammatory myopathy.: Dysphonia and dysphagia as early manifestations of autoimmune inflammatory myopathy.Am J Otolaryngol. 2020 Oct 03;42(1):102747Authors: Weinreb SF, Piersiala K, Hillel AT, Akst LM, Best SRAbstract PURPOSE: While dysphagia is a recognized manifestation of autoimmune inflammatory myopathy, a relationship between myositis and dysphonia or laryngeal pathology is not well-documented. We therefore sought to describe…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:57

Vascularised composite allotransplantation in solid organ transplant recipients: A systematic review.
Vascularised composite allotransplantation in solid organ transplant recipients: A systematic review.: Vascularised composite allotransplantation in solid organ transplant recipients: A systematic review.J Plast Reconstr Aesthet Surg. 2020 Aug 26;:Authors: Honeyman C, Stark HL, Fries CA, Gorantla VS, Davis MR, Giele HAbstract INTRODUCTION: A solid organ transplant (SOT) recipient, already taking immunosuppression, may represent the ideal candidate for vascularised composite allograft transplantation…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:56

Understanding the function of the temporoparietal junction
Large-scale brain networks underlying non-spatial attention updating: towards understanding the function of the temporoparietal junction: Publication date: Available online 10 October 2020Source: CortexAuthor(s): Katarzyna Jurewicz, Katarzyna Paluch, Tomasz Wolak, Andrzej WróbelFigures (5)Tables (1)Table 1Extras (1)DocumentCortexAvailable online 10 October 2020In Press, Journal Pre-proofWhat are Journal Pre-proof articles?Special Issue "Attention & Motor Processes": Research ReportLarge-scale…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:55

One-step lateral window approach for removal of benign minor sinus pathologies combined with transcrestal sinus floor elevation without bone grafts: a retrospective study
One-step lateral window approach for removal of benign minor sinus pathologies combined with transcrestal sinus floor elevation without bone grafts: a retrospective study: Publication date: Available online 11 October 2020Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): W.-B. Park, K.L. Kang, J.S. Park, J.-Y. HanFigures (2)Tables (2)Table 1Table 2Extras (3)DocumentDocumentDocumentInternational Journal of Oral and Maxillofacial SurgeryAvailable online 11 October 2020In Press,…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:54

Amiodarone-Associated Myxedema Coma.
Amiodarone-Associated Myxedema Coma.: Amiodarone-Associated Myxedema Coma.Am J Case Rep. 2020 Oct 10;21:e926757Authors: Zagorski E, Jayatilaka S, Hirani F, Donato AAbstract BACKGROUND Myxedema coma is an uncommon severe thyroid disorder that is fatal in 25-60% of cases. Although the differential diagnosis for altered mental status is extensive, including many more common causes such as infection, medication changes, electrolyte abnormalities, and exacerbation of chronic illnesses, profound…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:53

Rat Bite Fever
Rat Bite Fever: The First Case Report from Qatar.: Rat Bite Fever: The First Case Report from Qatar.Am J Case Rep. 2020 Oct 10;21:e925647Authors: Khatib MY, Elshafei MS, Mutkule DP, Shabana AM, Chengamaraju D, Nashwan AJAbstract BACKGROUND Rat bite fever (RBF) is a rare but fatal zoonotic disease caused by infections with various bacteria, which are transmitted from rats or other rodents. Only a few patients worldwide are diagnosed with RBF annually. RBF can be fatal if left untreated, with…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:53

Αφαίρεση διαφημίσεων


"Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi"[jour]; +23 new citations
"Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi"[jour]; +23 new citations: 1Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Oct 7;55(10):913-920. doi: 10.3760/cma.j.cn115330-20200225-00126.[Clinical application of the gasless unilateral axillary approach in endoscopic thyroid surgery][Article in Chinese]J J Xu 1, L Z Zhang 2, Q H Zhang 2, H W Guo 1, Z Tan 1, J F Wang 1, L H Jiang 1, C M Zheng 1, M H Ge 1, X B Lan 3Affiliations expandPMID: 33036505 DOI: 10.3760/cma.j.cn115330-20200225-00126Abstract…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:52

Five Specific Tongue Movements in a Healthy Population .. : rolling: 83.7%, cloverleaf: 14.7%, folding: 27.5%, twisting left: 36.1% and twisting right: 35.6%
Five Specific Tongue Movements in a Healthy Population: AbstractThe importance of tongue mobility on speech, oral food transport, and swallowing is well recognized. However, whether the individual tongue mobility influences postoperative function in oral cancer treatment remains to be elucidated. This study assesses the ability to perform five tongue movements as rolling, twisting (two sides), folding, and the ‘cloverleaf’ in a healthy population. Because a tumor in oral cancer patients often restricts…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:50

Single injection of Omalizumab in the treatment of Chronic Spontaneous Urticaria
An observational study on the efficacy of single injection of Omalizumab in the treatment of Chronic Spontaneous Urticaria: AbstractBackgroundChronic Spontaneous Urticaria (CSU) is one of the most challenging therapeutic problems faced by dermatologists. Omalizumab is a third line drug for CSU which is currently recommended as monthly injections for six months.AimTo study the efficacy of single injection of Omalizumab in the treatment of CSU.MethodsThis was a prospective single center observational…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:47

The diverse methods of bleomycin delivery in cutaneous warts
The diverse methods of bleomycin delivery in cutaneous warts: A literature review: AbstractBleomycin is a useful treatment option for recalcitrant verrucae. Several different methods of bleomycin delivery have been described, including intralesional injection, intralesional injection combined with laser, microneedling, multiple puncture and adhesive tape. We reviewed the literature to evaluate the various methods of bleomycin administration to treat warts, including the different doses, instruments…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:45

Personalized injective protocol (Botutouch) for botulinum toxin application in aesthetic medicine
An Italian experience of a new personalized injective protocol (Botutouch) for botulinum toxin application in aesthetic medicine: Botulinum toxin typeA(BoNTA)is widely used in aesthetic medicine as primary treatment to reduce facial wrinkles.Major unmet needs in the field of the injection techniques include dilution factor, injected volume and site.Since 2013,an innovative protocol has been developed in our clinic that works on a double dilution volume,identifies the injection site according to the…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:45

Purely intra-foraminal meningioma in the cervical spine
Purely intra-foraminal meningioma in the cervical spine: Publication date: Available online 10 October 2020Source: World NeurosurgeryAuthor(s): Benjamin Pommier, Alexandre Vasiljevic, Cédric BarreyAbstractMeningiomas are mostly benign intradural tumours. Concerning the spine, some of them can extend outside the canal or even develop extradurally but their primary attach is often located in the vertebral canal. Here we present the case of an exceptional purely intra-foraminal meningioma mimicking…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:44

Efficiency of endovascular therapy for bilateral cavernous sinus dural arteriovenous fistula
Efficiency of endovascular therapy for bilateral cavernous sinus dural arteriovenous fistula: Publication date: Available online 10 October 2020Source: World NeurosurgeryAuthor(s): Anchalee Churojana, Ittichai Sakarunchai, Thaweesak Aurboonyawat, Ekawut Chankaew, Pattarawit Withayasuk, Boonrerk SangpetngamAbstractBackgroundThe principles of endovascular treatment of bilateral cavernous sinus dural arteriovenous fistula (CS-dAVF) are not well established due to the complexity in the number of fistula…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:43

Severe tracheobronchial harm due to lithium button battery aspiration: An in vitro study of the pathomechanism and injury pattern
Severe tracheobronchial harm due to lithium button battery aspiration: An in vitro study of the pathomechanism and injury pattern: Publication date: December 2020Source: International Journal of Pediatric Otorhinolaryngology, Volume 139Author(s): Johannes Voelker, Christine Voelker, Jonas Engert, Philipp Schendzielorz, Rudolf Hagen, Kristen RakFigures (6)Extras (1)Multimedia component 1International Journal of Pediatric OtorhinolaryngologyVolume 139, December 2020, 110431Severe tracheobronchial harm…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:42

Eosinophilic esophagitis with and without airway involvement in children
Eosinophilic esophagitis with and without airway involvement in children – A comparative analysis: Publication date: December 2020Source: International Journal of Pediatric Otorhinolaryngology, Volume 139Author(s): Varun Bora, Anthony Olive, Eric Chiou, Priya Raj, Deepak MehtaFigures (2)Tables (2)Table 1Table 2International Journal of Pediatric OtorhinolaryngologyVolume 139, December 2020, 110422Eosinophilic esophagitis with and without airway involvement in children – A comparative analysisAuthor…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:42

Brain Radiation Induced Extracranial Abscopal Effects in Metastatic Melanoma
Brain Radiation Induced Extracranial Abscopal Effects in Metastatic Melanoma: Historically, the brain has been viewed as a specialized neurovascular inert organ with a distinctive immune privilege. Therefore, radiation-induced extracranial abscopal effects would be considered an unusual phenomenon due to the difficulty of the immunogenic signaling molecules to travel across the blood-brain barrier (BBB). However, it is now possible that localized central nervous system radiation has the ability to…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:40

Concurrent β-blocker Use is Associated With Improved Outcome in Esophageal Cancer Patients Who Undergo Chemoradiation: A Retrospective Matched-pair Analysis
Concurrent β-blocker Use is Associated With Improved Outcome in Esophageal Cancer Patients Who Undergo Chemoradiation: A Retrospective Matched-pair Analysis: Background: β-blocker use has been associated with improved outcomes in a number of different malignancies; however, the impact of β-blockade in esophageal cancer is not been well characterized. We compared the outcomes of esophageal cancer patients based on β-blocker usage. Methods: The charts of all 418 patients treated with radiation…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:39

Solitary chemosensory cells are innervated by trigeminal nerve endings and autoregulated by cholinergic receptors
Solitary chemosensory cells are innervated by trigeminal nerve endings and autoregulated by cholinergic receptors: BackgroundSolitary chemosensory cells (SCCs) in the murine nasal epithelium are discrete specialized cells that respond to irritants and activate trigeminal nerve fibers through the release of acetylcholine (ACh), resulting in local neurogenic inflammation. In addition to releasing ACh, SCCs are the exclusive epithelial source of interleukin (IL)‐25. In humans, SCCs are significantly…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:39

Clues that mitochondria are involved in the hair cycle clock
Clues that mitochondria are involved in the hair cycle clock: MPZL3 regulates entry into and progression of murine hair follicle cycling: AbstractThe molecular nature of the hair cycle clock (HCC), i.e. the intrinsic oscillator system that drives hair follicle (HF) cycling, remains incompletely understood; therefore, all relevant key players need to be identified. Here, we present evidence that implicates myelin protein zero‐ like 3 (MPZL3), a multifunctional nuclear‐encoded mitochondrial protein…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:39

Adult‐onset eosinophilic airway diseases
Adult‐onset eosinophilic airway diseases: AbstractEosinophilic airway inflammation is one of the cardinal features of allergic airway diseases such as atopic asthma and allergic rhinitis. These childhood‐onset conditions are mediated by allergen and allergen‐specific IgE and often accompanied by other allergic diseases including food allergy and eczema. They can develop consecutively in the same patient, which is referred to as an allergic march. In contrast, some phenotypes of asthma, nonsteroidal…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:38

Longitudinal egg‐specific regulatory T and B cell development
Longitudinal egg‐specific regulatory T and B cell development: insights from primary prevention clinical trials examining the timing of egg introduction: AbstractBackgroundEgg allergy affects almost 1 in 10 Australian infants. Early egg introduction has been associated with a reduced risk in developing egg allergy, however the immune mechanisms underlying this protection remain unclear.ObjectiveTo examine the role of regulatory immune cells in tolerance induction during early egg introduction.MethodsCryopreserved…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:38

Cytomorphologic analysis of clear cell papillary renal cell carcinoma: Distinguishing diagnostic features
Cytomorphologic analysis of clear cell papillary renal cell carcinoma: Distinguishing diagnostic features: BackgroundClear cell papillary renal cell carcinoma (CCPRCC) shares histomorphologic and immunophenotypic features with clear cell RCC (CCRCC) and papillary RCC (PRCC).MethodsWe compared the cytomorphology, immunoprofile, and clinical management of CCPRCC (n = 18), CCRCC (n = 20), and PRCC (n = 18).ResultsUseful cytomorphologic features for comparing CCPRCC with CCRCC include 3‐dimensional clusters…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:37

"Med Oral Patol Oral Cir Bucal"[jour]; +19 new citations
"Med Oral Patol Oral Cir Bucal"[jour]; +19 new citations: 1Med Oral Patol Oral Cir Bucal. 2020 Aug 27;24168. doi: 10.4317/medoral.24168. Online ahead of print.Oral pigmented lesions: a retrospective analysis from BrazilD-M Albuquerque 1, J-L Cunha 2, A-L Roza, L-P Arboleda, A-R Silva, M-A Lopes, P-A Vargas, J Jorge, O-P Almeida, A-C Abrahão, M Agostini, M-J Romañach, B-A AndradeAffiliations expandPMID: 32856618 DOI: 10.4317/medoral.24168Free articleAbstractBackground: Pigmented lesions are uncommon…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:37

Type I interferon signaling limits viral vector priming of CD8+ T cells during initiation of vitiligo and melanoma immunotherapy
Type I interferon signaling limits viral vector priming of CD8+ T cells during initiation of vitiligo and melanoma immunotherapy: AbstractVitiligo is an autoimmune skin disease in which epidermal melanocytes are targeted for destruction by CD8+ T cells specific for melanocyte/melanoma‐shared antigens. IFNγ is the central cytokine driving disease but the role of type I IFN in vitiligo remains unclear. We investigated the functional role of type I IFN during vitiligo progression using two different…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:35

Rapid drink challenge in high‐resolution esophageal manometry
The added value of symptom analysis during a rapid drink challenge in high‐resolution esophageal manometry: AbstractIntroductionPatients with esophageal symptoms often remain with an uncertain diagnosis after high‐resolution manometry.AimTo determine the added value of concomitant pressure and symptom analysis in response to a rapid drink challenge (RDC).MethodsIn consecutive patients referred for esophageal manometry, a RDC consisting in free drinking of 200 ml of water as quick as possible was…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:34

Skin fibrosis . High‐Fluence Light Emitting Diode‐Red Light Inhibits Cell Cycle Progression in Human Dermal Fibroblasts
High‐Fluence Light Emitting Diode‐Red Light Inhibits Cell Cycle Progression in Human Dermal Fibroblasts: AbstractSkin fibrosis is a debilitating feature of several systemic and dermatologic diseases. While current treatment options carry significant risk of side effects and recurrence, high‐fluence light emitting diode‐generated red light (LED‐RL) is an alternative therapeutic that is safe, non‐invasive, and accessible. We previously demonstrated LED‐RL decreases fibroblast proliferation, a key pathogenic…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:33

Σήμανση της παραπάνω ενότητας ως αναγνωσμένης

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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia,

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