Happy New Year ! God is our strength. Let Him be the strong foundation of our life so that we will not stumble when things go bad.

Alexandros Sfakianakis
Anapafseos 5 . Agios Nikolaos
Crete.Greece.72100
2841026182

6932607174
alsfakia

Journals for Dec 31st.2019

1	abqls-210rm.html	Read the latest Journal of Clinical Neurophysiology – Vol. 37, No. 1, January 2020.eml
2	agx3v-nxz96.html	Read the latest Journal of Occupational and Environmental Medicine – Vol. 62, No. 1, January 2020.eml
3	a2pyg-idobp.html	Read the latest Journal of Pediatric Gastroenterology and Nutrition – Vol. 70, No. 1, January 2020.eml
4	am5d4-hm0p9.html	Read the latest Optometry and Vision Science – Vol. 97, No. 1, January 2020.eml
5	a8zjp-vl1jd.html	Read the latest Sports Medicine and Arthroscopy Review – Vol. 28, No. 1, March 2020.eml
6	af9sr-7z3bf.html	Read the latest The Neurologist – Vol. 25, No. 1, January 2020.eml
7	azq8x-wluzd.html	Scan Blog_ He Jiankui Given Jail Term, This Week’s PLOS, Science of the Past and Future, more.eml
8	atqd0-2c1u5.html	Skeletal Radiology, Vol. 49, Issue 2 – New Issue Alert.eml
9	azxgh-r58yo.html	Success with Health and Well-Being Coaching Codes.eml
10	a25lz-lcojy.html	Video Updates – Best of Oncology East 2019.eml

1	ah7mf-cfdsk.html	PAP Alert – Journal of Hypertension.eml
2	a0k4n-yj6u3.html	Pediatrics eFirst 30 Dec 2019.eml
3	asnwh-jy9qs.html	Persistent organic pollutants in maternal blood linked to smaller fetal size, NIH study suggests.eml
4	aqr9w-e58xl.html	Physiother – J Indian Assoc Physiother – New issue online.eml
5	au4xd-btk90.html	Psychiatrist Engaged in Research Misconduct, Says Gov’t Watchdog.eml
6	aikl5-joypm.html	Read the latest ACSM’s Health & Fitness Journal – Vol. 24, No. 1, January_February 2020.eml
7	a9440-ht1zh.html	Read the latest AIDS – Vol. 34, No. 2, February 1, 2020.eml
8	aerfo-a039h.html	Read the latest Clinical Journal of Sport Medicine – Vol. 30, No. 1, January 2020.eml
9	amyir-lwf64.html	Read the latest Health Physics – Vol. 118, No. 2, February 2020.eml
10	aun9l-6hzmi.html	Read the latest JAAOS – Journal of the American Academy of Orthopaedic Surgeons – Vol. 28, No. 2, January 15, 2020.eml
11	ak1ms-fthmt.html	Read the latest Journal of Cardiovascular Pharmacology – Vol. 75, No. 1, January 2020.eml

1	apb23-f2z9e.html	Molecular Medicine Reports – Volume_21 Number_2.eml
2	aewrp-c3b5i.html	Music Theory Spectrum Advance articles.eml
3	aps13-500cj.html	New OnlineFirst articles available for Ear, Nose & Throat Journal.eml
4	afj2m-m2ke0.html	New OnlineFirst articles available for Otolaryngology–Head and Neck Surgery.eml
5	al0um-esfvo.html	Oral Oncology_ Alert 30 December.eml
6	ajewk-d8hia.html	Pakistan Journal of Biological Sciences – Current Issue.eml
7	ajqeq-k60ht.html	Palaeogeography, Palaeoclimatology, Palaeoecology _ Volume 539.eml
8	a0zi1-zvfow.html	PAP Alert – AIDS.eml
9	a3eg1-c6h2a.html	PAP Alert – American Journal of Therapeutics.eml
10	azlyf-ij2qw.html	PAP Alert – Current Opinion in Cardiology.eml
11	ap6uf-nxazm.html	PAP Alert – Journal of Cardiovascular Medicine.eml

1	anmot-oz9e8.html	J Curr Oncol – New issue online.eml
2	aq0y9-4otgb.html	J Pharm Bioall Sci – New issue online.eml
3	ac3c9-5jw5k.html	JAMA Online First.eml
4	aekn9-h8d48.html	Journal of Acupuncture and Tuina Science, Vol. 17, Issue 6 – New Issue Alert.eml
5	aunmb-7g05a.html	Journal of Church and State Advance articles.eml
6	aecmn-fmhjs.html	Journal of Social History Advance articles.eml
7	anvrs-rzgc5.html	Latest Articles Alert – PAIN Reports.eml
8	abq6s-slmi9.html	Libyan Int Med Univ J – New issue online.eml
9	aeehg-1xuqu.html	Med Gas Res – New issue online.eml
10	amr7i-y7eqt.html	Menoufia Med J – New issue online.eml
11	acayq-zou17.html	Modern Judaism – A Journal of Jewish Ideas and Experience Advance articles.eml

1	agzpc-a8q50.html	eTOC alert_ J Food Allergy December 2019.eml
2	av3xt-kzie9.html	eTOC alert_ Journal of Precision Respiratory Medicine December 2019.eml
3	absxh-9iw72.html	Eurasian J Pulmonol – New issue online.eml
4	asblo-o6c2o.html	Expanding the differential of superficial tumors with round cell morphology_ report of three cases of…eml
5	ag2to-8h5pf.html	Highlighted Papers from the December Issue.eml
6	aj07y-663e2.html	How to Nail Down Your Allergy Triggers.eml
7	aqrmr-d1o4d.html	Hyperallergic’s Best of 2019.eml
8	ay6g2-q4amw.html	Ibnosina J Med Biomed Sci – New issue online.eml
9	awk58-65n1e.html	International Immunology Advance articles.eml
10	axnxj-0d0fj.html	ISLE_ Interdisciplinary Studies in Literature and Environment Advance articles.eml
11	amzwp-u2cnm.html	J Cardiothorac Trauma – New issue online.eml

1	a5ags-rmh6x.html	American Literary History Advance articles.eml
2	ad6a4-pdjdr.html	Annals of Work Exposures and Health Advance articles.eml
3	ayxqe-5tzv3.html	Cancer Control, 2019 highlights.eml
4	ahen1-ldtcd.html	Church emergency readiness_ EMS resolutions.eml
5	ap75k-2kl3t.html	Clinical Infectious Diseases Advance articles.eml
6	aqhly-p6v7a.html	Daily News_ FDA Approves AstraZeneca’s Lynparza, Myriad Genetics’ CDx for BRCA-Positive Pancreatic Cancer.eml
7	apubs-ac38k.html	Das Gottesverständnis bei Kant und sein Beitrag zur psychopathologischen Wahndefinition, The Most Important…eml
8	a2ze6-4zqf8.html	Digit Med – New issue online.eml
9	a00cz-11fzv.html	Don’t Forget Your Year-end Gift in Support of Thyroid Health!.eml
10	aw9hm-hstak.html	Early View Alert_ Australasian Journal of Dermatology.eml
11	a6wrg-wjugl.html	Early View Alert_ International Forum of Allergy & Rhinology.eml

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com, Telephone consultation 11855 int 1193,

Metabolism of Reactive Oxygen Species in Osteosarcoma and Potential Treatment Applications
Cells, Vol. 9, Pages 87: Metabolism of Reactive Oxygen Species in Osteosarcoma and Potential Treatment Applications: Cells, Vol. 9, Pages 87: Metabolism of Reactive Oxygen Species in Osteosarcoma and Potential Treatment ApplicationsCells doi: 10.3390/cells9010087Authors: Wei Sun Bing Wang Xing-Long Qu Bi-Qiang Zheng Wen-Ding Huang Zheng-Wang Sun Chun-Meng Wang Yong Chen Background: The present study was designed to explore the underlying role of hypoxia-inducible factor 1α (HIF-1α)…

Medicine by Alexandros G. Sfakianakis

10:15

Mechanical Deformation Mediated Transmembrane Transport
Mechanical Deformation Mediated Transmembrane Transport: Transmembrane transport is reported to be controlled dynamically and precisely, yet without restructuring molecules by mechanical deformation. This strategy can dynamically regulate the transport of molecules across liposomal bilayer by stretching and loosening. The transport can be switched on and off, and accurately tuned by varying strain. The entire transport process can be simply regulated by applying external mechanical force. AbstractTransmembrane…

Medicine by Alexandros G. Sfakianakis

10:15

Conversion Surgery in Metastatic Gastric Cancer and Cancer Dormancy as a Prognostic Biomarker
Cancers, Vol. 12, Pages 86: Conversion Surgery in Metastatic Gastric Cancer and Cancer Dormancy as a Prognostic Biomarker: Cancers, Vol. 12, Pages 86: Conversion Surgery in Metastatic Gastric Cancer and Cancer Dormancy as a Prognostic BiomarkerCancers doi: 10.3390/cancers12010086Authors: Hun Jee Choe Jin Won Kim Song-Hee Han Ju Hyun Lee Sang-Hoon Ahn Do Joong Park Ji-Won Kim Yu Jung Kim Hye Seung Lee Jee Hyun Kim Hyung-Ho Kim Keun-Wook Lee The role of conversion surgery in…

Medicine by Alexandros G. Sfakianakis

10:14

Admissions for ambulatory care sensitive conditions on rural islands and their association with patient experience
Admissions for ambulatory care sensitive conditions on rural islands and their association with patient experience: a multicentred prospective cohort study: ObjectivesThe rate of admissions for ambulatory care sensitive conditions (ACSCs) is a key outcome indicator for primary care, and patient experience (PX) is a crucial process indicator. Studies have reported higher rates of admission for ACSCs in rural areas than in urban areas. Whether there is an association between admissions for ACSCs and…

Medicine by Alexandros G. Sfakianakis

10:14

Is there a causal relationship between acute stage sensorimotor cortex activity and the development of chronic low back pain?
Is there a causal relationship between acute stage sensorimotor cortex activity and the development of chronic low back pain? a protocol and statistical analysis plan: IntroductionWhy some people develop chronic pain following an acute episode of low back pain is unknown. Recent cross-sectional studies have suggested a relationship between aberrant sensorimotor cortex activity and pain persistence. The UPWaRD (Understanding persistent Pain Where it ResiDes) cohort study is the first prospective,…

Medicine by Alexandros G. Sfakianakis

10:13

Paid disability support for adults with acquired neurological disability and complex needs
Understanding the factors that influence the quality of paid disability support for adults with acquired neurological disability and complex needs: a scoping review protocol: IntroductionAdults with disability as the result of an acquired neurological disorder often have varying and complex support needs. Consequently, adults with complex needs often require paid support to enable them to exercise choice and control and participate fully and effectively in society. Given support is so critical for…

Medicine by Alexandros G. Sfakianakis

10:13

Tonsil-Derived Mesenchymal Stem Cells
Cells, Vol. 9, Pages 89: Tensin-3 Regulates Integrin-Mediated Proliferation and Differentiation of Tonsil-Derived Mesenchymal Stem Cells: Cells, Vol. 9, Pages 89: Tensin-3 Regulates Integrin-Mediated Proliferation and Differentiation of Tonsil-Derived Mesenchymal Stem CellsCells doi: 10.3390/cells9010089Authors: Gi Cheol Park Hyung-Sik Kim Hee-Young Park Yoojin Seo Ji Min Kim Sung-Chan Shin Hyun-Keun Kwon Eui-Suk Sung Jin-Choon Lee Byung-Joo Lee Human palatine tonsils are potential…

Medicine by Alexandros G. Sfakianakis

10:12

PP2A Deficiency Enhances Carcinogenesis of Lgr5+ Intestinal Stem Cells Both in Organoids and In Vivo
Cells, Vol. 9, Pages 90: PP2A Deficiency Enhances Carcinogenesis of Lgr5+ Intestinal Stem Cells Both in Organoids and In Vivo: Cells, Vol. 9, Pages 90: PP2A Deficiency Enhances Carcinogenesis of Lgr5+ Intestinal Stem Cells Both in Organoids and In VivoCells doi: 10.3390/cells9010090Authors: Yu-Ting Yen May Chien Yung-Chih Lai Dao-Peng Chen Cheng-Ming Chuong Mien-Chie Hung Shih-Chieh Hung In most cancers, cellular origin and the contribution of intrinsic and extrinsic factors toward…

Medicine by Alexandros G. Sfakianakis

10:12

HbA1c variability in adults with type 1 diabetes on continuous subcutaneous insulin infusion (CSII) therapy compared to multiple daily injection (MDI) treatment
HbA1c variability in adults with type 1 diabetes on continuous subcutaneous insulin infusion (CSII) therapy compared to multiple daily injection (MDI) treatment: ObjectiveTo determine if continuous subcutaneous insulin infusion (CSII) therapy is associated with lower glycated haemoglobin (HbA1c) variability (long-term glycaemic variability; GV) relative to multiple daily injection (MDI) treatment in adults with type 1 diabetes mellitus (T1DM).DesignRetrospective audit.Setting and participantsClinic…

Medicine by Alexandros G. Sfakianakis

10:12

Which public health interventions are effective in reducing morbidity, mortality and health inequalities from infectious diseases amongst children in low-income and middle-income countries (LMICs): protocol for an umbrella review
Which public health interventions are effective in reducing morbidity, mortality and health inequalities from infectious diseases amongst children in low-income and middle-income countries (LMICs): protocol for an umbrella review: IntroductionDespite significant progress in the last few decades, infectious diseases remain a significant threat to children’s health in low-income and middle-income countries. Effective means of prevention and control for these diseases exist, making any differences in…

Medicine by Alexandros G. Sfakianakis

10:11

Medical education quality assurance
Realist evaluation of UK medical education quality assurance: ObjectivesThe aim of the study was to explore what components of the General Medical Council’s (GMC) Quality Assurance Framework work, for whom, in what circumstances and how?SettingUK undergraduate and postgraduate medical education and training.ParticipantsWe conducted interviews with a stratified sample of 36 individuals. This included those who had direct experiences, as well as those with external insights, representing local, national…

Medicine by Alexandros G. Sfakianakis

10:11

AMEND study protocol: a case-control study to assess the long-term impact of invasive meningococcal disease
AMEND study protocol: a case-control study to assess the long-term impact of invasive meningococcal disease in Australian adolescents and young adults: IntroductionInvasive meningococcal disease (IMD) primarily causes disease in young children and adolescents and can cause long-term disability. Many countries are considering implementation of meningococcal B and/or meningococcal ACWY vaccines to control meningococcal disease. Estimating the cost-effectiveness of meningococcal vaccine programme is…

Medicine by Alexandros G. Sfakianakis

10:11

Feasibility study of early outpatient review and early cardiac rehabilitation after cardiac surgery
Feasibility study of early outpatient review and early cardiac rehabilitation after cardiac surgery: mixed-methods research design–a study protocol: IntroductionFollowing cardiac surgery, patients currently attend an outpatient review 6 weeks after hospital discharge, where recovery is assessed and suitability to commence cardiac rehabilitation (CR) is determined. CR is then started from 8 weeks. Following a median sternotomy, cardiac surgery patients are required to refrain from upper body exercises,…

Medicine by Alexandros G. Sfakianakis

10:10

Housing situation and healthcare for patients in a psychiatric centre
Housing situation and healthcare for patients in a psychiatric centre in Berlin, Germany: a cross-sectional patient survey: ObjectiveTo determine the housing situation among people seeking psychiatric treatment in relation to morbidity and service utilisation.DesignCross-sectional patient survey.SettingPsychiatric centre with a defined catchment area in Berlin, Germany, March–September 2016.Participants540 psychiatric inpatients including day clinics (43.2% of all admitted patients in the study period…

Medicine by Alexandros G. Sfakianakis

10:10

Supporting people with type 2 diabetes
Supporting people with type 2 diabetes in effective use of their medicine through mobile health technology integrated with clinical care (SuMMiT-D Feasibility): a randomised feasibility trial protocol: IntroductionType 2 diabetes is common, affecting over 400 million people worldwide. Risk of serious complications can be reduced through use of effective treatments and active self-management. However, people are often concerned about starting new medicines and face difficulties in taking them regularly….

Medicine by Alexandros G. Sfakianakis

10:10

Safety of switching from vitamin K antagonist to non-vitamin K antagonist oral anticoagulant in frail elderly with atrial fibrillation: rationale and design of the FRAIL-AF randomised controlled trial
Safety of switching from vitamin K antagonist to non-vitamin K antagonist oral anticoagulant in frail elderly with atrial fibrillation: rationale and design of the FRAIL-AF randomised controlled trial: IntroductionClinical guidelines recommend non-vitamin K antagonist oral anticoagulants (NOACs) over vitamin K antagonists (VKAs) for stroke prevention in most patients with atrial fibrillation (AF). Frail elderly were under-represented in the landmark NOAC-trials, leaving a knowledge gap on the optimal…

Medicine by Alexandros G. Sfakianakis

10:09

Fatty acid profile and in vitro biological properties of two Rosacea species (Pyrus glabra and Pyrus syriaca)
Fatty acid profile and in vitro biological properties of two Rosacea species (Pyrus glabra and Pyrus syriaca), grown as wild in Iran: One of the most important findings of this study is the introduction of Pyrus glabra and Pyrus syriaca as a new source of plant oils. The significant amount of antioxidants, especially in P. glabra oil, may serve as a dietary source of natural antioxidants and increase the stability and quality of food products. The results showed that the P. glabra seed oil is rich…

Medicine by Alexandros G. Sfakianakis

10:09

Sleep problems of healthcare workers in tertiary hospital
Sleep problems of healthcare workers in tertiary hospital and influencing factors identified through a multilevel analysis: a cross-sectional study in China: ObjectivesSleep problems are common among healthcare workers, especially among those who work in tertiary hospitals; however, studies focusing on healthcare workers in tertiary hospitals in China are limited. Therefore, we aimed to examine the prevalence of sleep problems among tertiary hospital employees in China and identify associated factors.DesignCross-sectional…

Medicine by Alexandros G. Sfakianakis

10:08

Improving chronic pain management with eHealth and mHealth
Improving chronic pain management with eHealth and mHealth: study protocol for a randomised controlled trial: IntroductionChronic pain has become a matter of public health concern due to its high prevalence and because public costs associated with treatment and disability increase each year. Research suggests that limitations in the traditional assessment of chronic pain patients limit the effectiveness of current medical treatments. The use of technology might serve change patient traditional monitoring…

Medicine by Alexandros G. Sfakianakis

10:08

Healthcare utilisation for eating disorders among patients with depression
Healthcare utilisation for eating disorders among patients with depression: a cross-sectional study in Taiwan: ObjectivesAlthough depressed patients may have a comorbid eating disorder (ED), to date, no study has focused on healthcare utilisation among this population. This study was designed to investigate the characteristics of healthcare service utilisation among depressed patients with ED.DesignA cross-sectional study.SettingThis population-based study used claims data from Taiwan’s National…

Medicine by Alexandros G. Sfakianakis

10:07

Effect of involving certified healthcare assistants in primary care
Effect of involving certified healthcare assistants in primary care in Germany: a cross-sectional study: ObjectivesGrowing prevalence of chronic diseases and limited resources are the key challenges for future healthcare. As a promising approach to maintain high-quality primary care, non-physician healthcare professionals have been trained to broaden qualifications and responsibilities. This study aimed to assess the influence of involving certified healthcare assistants (HCAs, German: Versorgungsassistent/in…

Medicine by Alexandros G. Sfakianakis

10:04

Womens health-related vulnerabilities in natural disasters
Womens health-related vulnerabilities in natural disasters: a systematic review protocol: IntroductionThere is a paucity of evidence identifying both the physical and psychological health risks and underlying causes of women’s health-related vulnerabilities related to natural disasters. Therefore, this systematic review will be conducted to determine the impact of natural disasters on women’s health from a global perspective.Methods and analysisFive electronic databases of health research, including…

Medicine by Alexandros G. Sfakianakis

10:04

Family-building decision aid and planning tool for young adult women after cancer treatment: protocol for preliminary testing of a web-based decision support intervention in a single-arm pilot study
Family-building decision aid and planning tool for young adult women after cancer treatment: protocol for preliminary testing of a web-based decision support intervention in a single-arm pilot study: IntroductionMany young adult female (YA-F) cancer survivors who received gonadotoxic therapy will experience fertility problems. After cancer, having a child will often require assisted reproductive technology (ART), surrogacy or adoption. However, there are significant informational, psychosocial, financial…

Medicine by Alexandros G. Sfakianakis

10:04

Adverse events and good practices in maternity wards
Multicentre cross-sectional study on adverse events and good practices in maternity wards in Brazil and Mexico: same problems, different magnitude: ObjectiveTo evaluate the quality of delivery care in maternity wards in Brazil and Mexico based on good practices (GP) and adverse events (AE), in order to identify priorities for improvement.DesignA multicentre cross-sectional study with data collection from medical records between 2015 and 2016 to compare indicators of maternal and neonatal GP and EA…

Medicine by Alexandros G. Sfakianakis

10:00

Does ‘online confidence predict application success and later academic performance in medical school?
Does ‘online confidence predict application success and later academic performance in medical school? A UK-based national cohort study: ObjectivesThe UK Clinical Aptitude Test (UKCAT) previously piloted an assessment of ‘online confidence’, where candidates were asked to indicate how confident they were with their answers. This study examines the relationship between these ratings, the odds of receiving an offer to study medicine and subsequent undergraduate academic performance.DesignNational cohort…

Medicine by Alexandros G. Sfakianakis

10:00

Healthcare in rural and underserved areas : Cost-effectiveness analysis of a physician deployment program to improve access
Cost-effectiveness analysis of a physician deployment program to improve access to healthcare in rural and underserved areas in the Philippines: ObjectivesThe objective of this study is to explore the cost-effectiveness of Doctor to the Barrios (DTTB), a physician deployment program in the Philippines.DesignCost-effectiveness analysis using decision tree models with a lifetime time horizon and probabilistic sensitivity analysis.SettingSocietal and healthcare perspectives.PopulationHypothetical cohort…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:59

Increased risk of bullous pemphigoid in dipeptidyl peptidase 4 inhibitors
Increased risk of bullous pemphigoid in dipeptidyl peptidase 4 inhibitors: A nationwide, population‐based, cohort study in Taiwan: AbstractRecent studies revealed the risk of bullous pemphigoid (BP) in patients with diabetes mellitus (DM) taking dipeptidyl peptidase 4 (DPP‐4) inhibitors. To clarify the relationship between taking DPP‐4 inhibitors and the risk of BP among patients with DM, we conducted a cohort study by using the National Health Insurance Research Database of Taiwan from 1 January…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:58

Successful Treatment of verruca plana with NB‐UVB: A Case report
Successful Treatment of verruca plana with NB‐UVB: A Case report: AbstractVerruca plana is a kind of benign proliferative skin disease that generally occurs in exposed parts, but the treatment of warts poses a therapeutic challenge for physicians, as there is no method, among numerous approaches, that has been proven effective for completely curing this disease. We report a case of verruca plana cured by narrow‐band ultraviolet B (NB‐UVB), which provides a new treatment of verruca plana.This article…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:58

Effect of Q‐switched Nd‐YAG laser on the clinical, pigmentary and immunological markers in the patients with lichen planus pigmentosus: A pilot study
Effect of Q‐switched Nd‐YAG laser on the clinical, pigmentary and immunological markers in the patients with lichen planus pigmentosus: A pilot study: AbstractThe persistent discolouration in lichen planus pigmentosus is secondary to persistent melanophages in superficial dermis in these patients. We evaluated the effect of Q‐switched Nd‐YAG laser on the clinical, pigmentary and immunological markers in the patients with lichen planus pigmentosus. Nine females with a clinical diagnosis of lichen…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:57

Microbial activities associated with human intestinal mucosal biofilms change mRNAs and microRNAs to promote carcinogenesis in mice [miRNA]
GSE108164 Microbial activities associated with human intestinal mucosal biofilms change mRNAs and microRNAs to promote carcinogenesis in mice [miRNA]: Contributors : Cynthia Sears ; Christian JobinSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Mus musculusDisrupted interactions between host and intestinal bacteria are implicated in the development of colorectal cancer (CRC). However, the functional impacts of these inter-kingdom interactions remain poorly defined….

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:56

Genes, Vol. 11, Pages 44: Porcine Epidemic Diarrhea Altered Colonic Microbiota Communities in Suckling Piglets
Genes, Vol. 11, Pages 44: Porcine Epidemic Diarrhea Altered Colonic Microbiota Communities in Suckling Piglets: Genes, Vol. 11, Pages 44: Porcine Epidemic Diarrhea Altered Colonic Microbiota Communities in Suckling PigletsGenes doi: 10.3390/genes11010044Authors: Zhen Tan Wanting Dong Yaqun Ding Xiangdong Ding Qin Zhang Li Jiang Porcine epidemic diarrhea (PED) is a major gastrointestinal disease afflicting suckling pigs that causes huge industrial economic losses. In this study, we investigated…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:55

The Practice of Pharmaceutics and the Obligation to Expand Access to Investigational Drugs
The Practice of Pharmaceutics and the Obligation to Expand Access to Investigational Drugs: AbstractDo pharmaceutical companies have a moral obligation to expand access to investigational drugs to patients outside the clinical trial? One reason for thinking they do not is that expanded access programs might negatively affect the clinical trial process. This potential impact creates dilemmas for practitioners who nevertheless acknowledge some moral reason for expanding access. Bioethicists have explained…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:55

SEOM clinical guidelines in hereditary breast and ovarian cancer (2019)
SEOM clinical guidelines in hereditary breast and ovarian cancer (2019): AbstractMutations in BRCA1 and BRCA2 high penetrance genes account for most hereditary breast and ovarian cancer, although other new high-moderate penetrance genes included in multigene panels have increased the genetic diagnosis of hereditary breast and ovarian cancer families by 50%. Multigene cancer panels provide new challenges related to increased frequency of variants of uncertain significance, new gene-specific cancer…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:55

Elevated Intraocular Pressure Causes Abnormal Reactivity of Mouse Retinal Arterioles
Elevated Intraocular Pressure Causes Abnormal Reactivity of Mouse Retinal Arterioles: Objective. Glaucoma is a leading cause of severe visual impairment and blindness. Although high intraocular pressure (IOP) is an established risk factor for the disease, the role of abnormal ocular vessel function in the pathophysiology of glaucoma gains more and more attention. We tested the hypothesis that elevated intraocular pressure (IOP) causes vascular dysfunction in the retina. Methods. High IOP was induced…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:55

Restoration of Autophagic Flux Rescues Oxidative Damage and Mitochondrial Dysfunction to Protect against Intervertebral Disc Degeneration
Restoration of Autophagic Flux Rescues Oxidative Damage and Mitochondrial Dysfunction to Protect against Intervertebral Disc Degeneration: Oxidative stress-induced mitochondrial dysfunction and nucleus pulposus (NP) cell apoptosis play crucial roles in the development of intervertebral disc degeneration (IDD). Increasing studies have shown that interventions targeting impaired autophagic flux can maintain cellular homeostasis by relieving oxidative damage. Here, we investigated the effect of curcumin…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:54

The Evolution of Positive and Negative Affect in a Longitudinal Sample of Children and Adolescents
The Evolution of Positive and Negative Affect in a Longitudinal Sample of Children and Adolescents: AbstractThis article explores the evolution of Positive and Negative Affect (PA and NA) and their relationship with a single-item measure of overall life satisfaction (OLS) through a five-year longitudinal study on 1696 ten to eighteen-year-olds in Catalonia (Spain). The results, which were obtained through structural equation modelling with a cross-lagged panel, show that mean scores for both PA and…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:37

Antibiotics, Vol. 9, Pages 10: Simple Carbohydrate Derivatives Diminish the Formation of Biofilm of the Pathogenic Yeast Candida albicans
Antibiotics, Vol. 9, Pages 10: Simple Carbohydrate Derivatives Diminish the Formation of Biofilm of the Pathogenic Yeast Candida albicans: Antibiotics, Vol. 9, Pages 10: Simple Carbohydrate Derivatives Diminish the Formation of Biofilm of the Pathogenic Yeast Candida albicansAntibiotics doi: 10.3390/antibiotics9010010Authors: Olena P. Ishchuk Olov Sterner Ulf Ellervik Sophie Manner The opportunistic human fungal pathogen Candida albicans relies on cell morphological transitions to develop…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:37

Medgadget’s Best Medical Technologies of 2019
Medgadget’s Best Medical Technologies of 2019: Wrapping up this year and looking back on the particularly interesting developments in medical technology, we at Medgadget are impressed and very excited about the future. We’re lucky to cover one of the most innovative fields of research and one that improves and saves lives. Having a constant eye on what’s new in medtech, we present what we believe are the most novel, smart, and medically important technologies we encountered in this passing year….

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:36

Description of a disease activity proforma for documentation of hidradenitis suppurativa severity and distribution, and suggestions for use as a patient‐reported outcome measure
Description of a disease activity proforma for documentation of hidradenitis suppurativa severity and distribution, and suggestions for use as a patient‐reported outcome measure: AbstractThe whole process is intuitive and can be completed in under five minutes using a combination of clinical examination and verbal patient questioning. The completed proforma enables the clinician to visualise a concise but comprehensive overview of HS activity and distribution for an individual patient. In addition…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:35

Cancers, Vol. 12, Pages 85: Molecular Genetics of Renal Cell Tumors: A Practical Diagnostic Approach
Cancers, Vol. 12, Pages 85: Molecular Genetics of Renal Cell Tumors: A Practical Diagnostic Approach: Cancers, Vol. 12, Pages 85: Molecular Genetics of Renal Cell Tumors: A Practical Diagnostic ApproachCancers doi: 10.3390/cancers12010085Authors: Reza Alaghehbandan Delia Perez Montiel Ana Silvia Luis Ondrej Hes Renal epithelial cell tumors are composed of a heterogeneous group of tumors with variable morphologic, immunohistochemical, and molecular features. A “histo-molecular” approach is…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:34

Cancers, Vol. 12, Pages 84: Real-World Data on Cabozantinib in Previously Treated Patients with Metastatic Renal Cell Carcinoma: Focus on Sequences and Prognostic Factors
Cancers, Vol. 12, Pages 84: Real-World Data on Cabozantinib in Previously Treated Patients with Metastatic Renal Cell Carcinoma: Focus on Sequences and Prognostic Factors: Cancers, Vol. 12, Pages 84: Real-World Data on Cabozantinib in Previously Treated Patients with Metastatic Renal Cell Carcinoma: Focus on Sequences and Prognostic FactorsCancers doi: 10.3390/cancers12010084Authors: Matteo Santoni Daniel Y. Heng Sergio Bracarda Giuseppe Procopio Michele Milella Camillo Porta Marc R….

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:34

Cells, Vol. 9, Pages 88: Vertically-Aligned Functionalized Silicon Micropillars for 3D Culture of Human Pluripotent Stem Cell-Derived Cortical Progenitors
Cells, Vol. 9, Pages 88: Vertically-Aligned Functionalized Silicon Micropillars for 3D Culture of Human Pluripotent Stem Cell-Derived Cortical Progenitors: Cells, Vol. 9, Pages 88: Vertically-Aligned Functionalized Silicon Micropillars for 3D Culture of Human Pluripotent Stem Cell-Derived Cortical ProgenitorsCells doi: 10.3390/cells9010088Authors: Alessandro Cutarelli Simone Ghio Jacopo Zasso Alessandra Speccher Giorgina Scarduelli Michela Roccuzzo Michele Crivellari Nicola Maria…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:34

Toxins, Vol. 12, Pages 16: Ephedra sinica Stapf and Gypsum Attenuates Heat-Induced Hypothalamic Inflammation in Mice
Toxins, Vol. 12, Pages 16: Ephedra sinica Stapf and Gypsum Attenuates Heat-Induced Hypothalamic Inflammation in Mice: Toxins, Vol. 12, Pages 16: Ephedra sinica Stapf and Gypsum Attenuates Heat-Induced Hypothalamic Inflammation in MiceToxins doi: 10.3390/toxins12010016Authors: Wonnam Kim Wonil Lee Eugene Huh Eunjung Choi Young Pyo Jang Yun-Kyung Kim Tae-Hee Lee Myung Sook Oh Ephedra sinica Stapf (EH) exert toxic effects, such as excitability, cardiac arrhythmia, and others. On the…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:34

Is Surgery-first Still a Reasonable Option in the Era of Neoadjuvant Chemotherapy for Resectable Pancreatic Cancer?
Is Surgery-first Still a Reasonable Option in the Era of Neoadjuvant Chemotherapy for Resectable Pancreatic Cancer?: The incidence of pancreatic ductal adenocarcinoma has risen rapidly. By 2030, it is likely to be the second most prevalent cause of death by cancer, following cancer of the lung. Unfortunately, most patients present with advanced disease. In fact, only 20% of patients are candidates for surgery. More research is needed to find dependable treatment options for this disease. Although…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:33

SEOM clinical guidelines in hereditary breast and ovarian cancer (2019)
SEOM clinical guidelines in hereditary breast and ovarian cancer (2019): AbstractMutations in BRCA1 and BRCA2 high penetrance genes account for most hereditary breast and ovarian cancer, although other new high-moderate penetrance genes included in multigene panels have increased the genetic diagnosis of hereditary breast and ovarian cancer families by 50%. Multigene cancer panels provide new challenges related to increased frequency of variants of uncertain significance, new gene-specific cancer…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:33

Porous high-density polyethylene (MEDPOR)
Retraction NotePublished: 30 December 2019Retraction Note to: Management of the large septal perforations with the support of porous high-density polyethylene (MEDPOR)Ilteris Murat Emsen European Journal of Plastic Surgery (2019)Cite this articleRetraction Note to: Eur J Plast Surg (2007) 29:277–283https://doi.org/10.1007/s00238-006-0103-9The Editor-in-Chief has retracted this article [1] because significant parts of the text and Figs. 1 to 6 and 7a were duplicated from a previously published article…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:33

Algorithmic Puzzles: History, Taxonomies, and Applications in Human Problem Solving
Algorithmic Puzzles: History, Taxonomies, and Applications in Human Problem Solving: Anany Levitin, Journal of Problem Solving, Dec 30, 2019 This is a fun read from a couple of years ago that turned up in an O’Reilly mailing list this week. While it will be of interest to psychologists and computer scientists, it will also give teachers ideas for class discussion or computation projects. The paper (15 page PDF) considers the nature or algorithmic puzzles, identifies two typologies based on the…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:30

Tumor uptake and associated greater efficacy of anti-Her2 immunoliposome does not rely on Her2 expression status: study of a docetaxel-trastuzumab immunoliposome on Her2+ breast cancer model (SKBR3)
Tumor uptake and associated greater efficacy of anti-Her2 immunoliposome does not rely on Her2 expression status: study of a docetaxel-trastuzumab immunoliposome on Her2+ breast cancer model (SKBR3): Nanoparticles have been used for decades in breast cancer. More recently, anti-human epidermal receptor 2 (Her2) immunoliposomes are of rising interest. However, recent studies have questioned the actual relevance of using anti-Her2 antibodies to improve liposome distribution and efficacy. Using standard…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:29

Utility of Ga68 prostate‐specific membrane antigen positron‐emission tomography for pre‐operative staging of high‐risk prostate cancer in a prospective cohort
Utility of Ga68 prostate‐specific membrane antigen positron‐emission tomography for pre‐operative staging of high‐risk prostate cancer in a prospective cohort: AbstractIntroductionTo assess the yield of Ga68 PSMA PET/CT added to the conventional staging of high‐risk prostate cancer in terms of altered staging and changes to management.MethodsPatients with high‐risk prostate cancer without metastatic disease on conventional staging referred for Ga68 PSMA PET/CT at Mercy Radiology, Auckland, New Zealand,…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:28

Why considering sexual differences is necessary when studying encephalopathy of prematurity through rodent models
Why considering sexual differences is necessary when studying encephalopathy of prematurity through rodent models: AbstractPreterm birth is a high‐risk factor for the development of gray and white matter abnormalities, referred to as “encephalopathy of prematurity,” that may lead to life‐long motor, cognitive, and behavioral impairments. The prevalence and clinical outcomes of encephalopathy of prematurity differ between sexes, and elucidating the underlying biological basis has become a high‐priority…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:28

The Invention of “Ethical AI”: How Big Tech Manipulates Academia to Avoid Regulation
The Invention of “Ethical AI”: How Big Tech Manipulates Academia to Avoid Regulation: Rodrigo Ochigame, The Intercept, Dec 30, 2019 According to this article, "Silicon Valley’s vigorous promotion of ‘ethical AI’ has constituted a strategic lobbying effort, one that has enrolled academia to legitimize itself." Playing a key role in this was Joi Ito and the MIT Media Lab. "The corporate, academic, and military proponents of ‘ethical AI’ have collaborated closely for mutual benefit," writes Rodrigo…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:28

Health and Occupational Injury Experienced by Child Farmworkers
IJERPH, Vol. 17, Pages 248: Health and Occupational Injury Experienced by Latinx Child Farmworkers in North Carolina, USA: IJERPH, Vol. 17, Pages 248: Health and Occupational Injury Experienced by Latinx Child Farmworkers in North Carolina, USAInternational Journal of Environmental Research and Public Health doi: 10.3390/ijerph17010248Authors: Thomas A. Arcury Taylor J. Arnold Sara A. Quandt Haiying Chen Gregory D. Kearney Joanne C. Sandberg Jennifer W. Talton Melinda F. Wiggins …

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:24

Assessing and Improving the Quality in Mental Health Services
IJERPH, Vol. 17, Pages 249: Assessing and Improving the Quality in Mental Health Services: IJERPH, Vol. 17, Pages 249: Assessing and Improving the Quality in Mental Health ServicesInternational Journal of Environmental Research and Public Health doi: 10.3390/ijerph17010249Authors: Lampros Samartzis Michael A. Talias Background: The mental health of the population consists of the three essential pillars of quality of life, economy, and society. Mental health services take care of the prevention…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:23

Potency of Papaya Leaf (Carica papaya L.) as Toxicant and Repellent against German Cockroach (Blattella germanica L.)
Potency of Papaya Leaf (Carica papaya L.) as Toxicant and Repellent against German Cockroach (Blattella germanica L.): Background and Objective: Papaya leaves have the potency to be developed as alternative insecticide to control the German cockroaches that have been resistant to synthetic insecticides. This study aimed to determine the potency of ethanolic extract of papaya leaf as toxicant and repellent against 2 populations of German cockroaches which are known resistant to synthetic insecticide….

Medicine by Alexandros G. Sfakianakis

09:22

Hypoglycemic Potential of Supplementation with a Vegetable and Legume Juice Formula in Type 2 Diabetic Patients
Hypoglycemic Potential of Supplementation with a Vegetable and Legume Juice Formula in Type 2 Diabetic Patients: Background and Objective: Type 2 diabetes affects a large number of people all over the world; hence, it is worthy to supplement those patients with a food formula containing biologically active ingredients that can help to control the disease and its complications. The present study was designed to prepare a plant formula in the form of a juice taken during treatment to synergies and…

Medicine by Alexandros G. Sfakianakis

09:20

Common Co-morbidities Are Challenging in the Diagnosis of Middle East Respiratory Syndrome (MERS-CoV) in Saudi Arabia
Common Co-morbidities Are Challenging in the Diagnosis of Middle East Respiratory Syndrome (MERS-CoV) in Saudi Arabia: Background and Objective: Middle East respiratory syndrome coronavirus (MERS-CoV) is a relatively recent human disease reported initially in Saudi Arabia in September, 2012. Morbidities investigation includes a process of excluding other possible options until certain suspected cases are confirmed. Material and Methods: In this study, we formulated a model under the authorization…

Medicine by Alexandros G. Sfakianakis

09:20

Symbiotic collision tumour of the scalp: squamous cell carcinoma and malignant melanoma
Symbiotic collision tumour of the scalp: squamous cell carcinoma and malignant melanoma: AbstractCutaneous collision tumours are the co‐existence of two tumours of different histopathological morphologies that coincide at the same or adjacent anatomical sites. A large scalp nodule excised from a 70 year‐old man revealed a collision tumour composed of cells of squamous carcinoma (SCC) and malignant melanoma. Immunohistochemistry using dual staining for melanoma and squamous cell carcinoma demonstrated…

Medicine by Alexandros G. Sfakianakis

09:19

Antioxidants, Vol. 9, Pages 32: Protective Role of Peroxiredoxins against Reactive Oxygen Species in Neonatal Rat Testicular Gonocytes
Antioxidants, Vol. 9, Pages 32: Protective Role of Peroxiredoxins against Reactive Oxygen Species in Neonatal Rat Testicular Gonocytes: Antioxidants, Vol. 9, Pages 32: Protective Role of Peroxiredoxins against Reactive Oxygen Species in Neonatal Rat Testicular GonocytesAntioxidants doi: 10.3390/antiox9010032Authors: Cristian O’Flaherty Annie Boisvert Gurpreet Manku Martine Culty Peroxiredoxins (PRDXs) are antioxidant enzymes that protect cells from oxidative stress and play a role in reactive…

Medicine by Alexandros G. Sfakianakis

09:19

Viruses, Vol. 12, Pages 41: Investigation of the Role of the Spike Protein in Reversing the Virulence of the Highly Virulent Taiwan Porcine Epidemic Diarrhea Virus Pintung 52 Strains and Its Attenuated Counterpart
Viruses, Vol. 12, Pages 41: Investigation of the Role of the Spike Protein in Reversing the Virulence of the Highly Virulent Taiwan Porcine Epidemic Diarrhea Virus Pintung 52 Strains and Its Attenuated Counterpart: Viruses, Vol. 12, Pages 41: Investigation of the Role of the Spike Protein in Reversing the Virulence of the Highly Virulent Taiwan Porcine Epidemic Diarrhea Virus Pintung 52 Strains and Its Attenuated CounterpartViruses doi: 10.3390/v12010041Authors: Chi-Fei Kao Hui-Wen Chang Porcine…

Medicine by Alexandros G. Sfakianakis

09:18

Microorganisms, Vol. 8, Pages 61: Prenatal Transfer of Gut Bacteria in Rock Pigeon
Microorganisms, Vol. 8, Pages 61: Prenatal Transfer of Gut Bacteria in Rock Pigeon: Microorganisms, Vol. 8, Pages 61: Prenatal Transfer of Gut Bacteria in Rock PigeonMicroorganisms doi: 10.3390/microorganisms8010061Authors: Maurine W. Dietz Joana F. Salles Bin-Yan Hsu Cor Dijkstra Ton G. G. Groothuis Marco van der Velde Yvonne I. Verkuil B. Irene Tieleman Vertebrates evolved in concert with bacteria and have developed essential mutualistic relationships. Gut bacteria are vital for…

Medicine by Alexandros G. Sfakianakis

09:18

Gene Expression Profiling of Head and Neck Tumors Identifies FOXP1 and SOX10 Expression as Useful for Distinguishing Ameloblastoma From Basaloid Salivary Gland Tumors
Gene Expression Profiling of Head and Neck Tumors Identifies FOXP1 and SOX10 Expression as Useful for Distinguishing Ameloblastoma From Basaloid Salivary Gland Tumors: Odontogenic tumors show considerable morphologic heterogeneity and at times the diagnosis can be challenging. Ameloblastoma, the most common odontogenic tumor, can have morphologic similarity to some salivary gland tumors and therefore we sought to identify biomarkers that might aid in the diagnosis by performing transcriptome wide…

Medicine by Alexandros G. Sfakianakis

09:18

Clinical Applications, Pitfalls, and Uncertainties of Thrombin Generation in the Presence of Platelets
JCM, Vol. 9, Pages 92: Clinical Applications, Pitfalls, and Uncertainties of Thrombin Generation in the Presence of Platelets: JCM, Vol. 9, Pages 92: Clinical Applications, Pitfalls, and Uncertainties of Thrombin Generation in the Presence of PlateletsJournal of Clinical Medicine doi: 10.3390/jcm9010092Authors: Marina Panova-Noeva Paola E.J. van der Meijden Hugo ten Cate Platelet-dependent thrombin generation is a helpful tool to assess ex vivo the interaction between platelets and plasma coagulation…

Medicine by Alexandros G. Sfakianakis

09:17

Why Uptake of Blended Internet-Based Interventions for Depression Is Challenging: A Qualitative Study on Therapists’ Perspectives
JCM, Vol. 9, Pages 91: Why Uptake of Blended Internet-Based Interventions for Depression Is Challenging: A Qualitative Study on Therapists’ Perspectives: JCM, Vol. 9, Pages 91: Why Uptake of Blended Internet-Based Interventions for Depression Is Challenging: A Qualitative Study on Therapists’ PerspectivesJournal of Clinical Medicine doi: 10.3390/jcm9010091Authors: Mayke Mol Claire van Genugten Els Dozeman Digna J. F. van Schaik Stasja Draisma Heleen Riper Jan H. Smit (1) Background:…

Medicine by Alexandros G. Sfakianakis

09:17

Journals for Dec 30th.2019
1a6ue1-xc26e.htmlMinds and Machines, Vol. 29, Issue 4 – New Issue Alert.eml 2asu1z-42vkx.htmlNervous Diseases and Mental Hygiene, Year 2019, Issue 08 -New Issue Alert..eml 3aewxb-lfl3g.htmlNew articles available for Clinical Medicine Insights_ Case Reports.eml 4acp2h-ocdmd.htmlNew articles available for Integrative Cancer Therapies.eml 5apzyx-ock1g.htmlOphthalmology in China, Year 2019, Issue 05 -New Issue Alert..eml 6axcdy-fec7g.htmlPAP Alert – Dermatologic Surgery.eml 7apmpz-cpiuh.htmlRadiologic…

Medicine by Alexandros G. Sfakianakis

09:13

70 Journals for Dec 28th.2019

Journals1apfrr-gsv90.htmlRead the latest The Journal of Strength & Conditioning Research – Vol. 34, No. 1, January 2020.eml 2abkgt-ly7fd.htmlRead the latest Transplantation – Vol. 104, No. 1, January 2020.eml 3apouu-64ym7.htmlReminder_ Get End-of-Year CME with JAMA Otolaryngology Clinical Challenges.eml 4ao6rp-sw2mv.htmlSaudi Endod J – New issue online.eml 5avesw-7q3zd.htmlScan Blog_ Investigation Following Moffitt Departures, NSF Nominee May Boost White House Ties, more.eml 6ag1ol-0gxo1.htmlSelectas…

Medicine by Alexandros G. Sfakianakis

Sat Dec 28, 2019 14:55

Journals for Dec 30th.2019

1	a6ue1-xc26e.html	Minds and Machines, Vol. 29, Issue 4 – New Issue Alert.eml
2	asu1z-42vkx.html	Nervous Diseases and Mental Hygiene, Year 2019, Issue 08 -New Issue Alert..eml
3	aewxb-lfl3g.html	New articles available for Clinical Medicine Insights_ Case Reports.eml
4	acp2h-ocdmd.html	New articles available for Integrative Cancer Therapies.eml
5	apzyx-ock1g.html	Ophthalmology in China, Year 2019, Issue 05 -New Issue Alert..eml
6	axcdy-fec7g.html	PAP Alert – Dermatologic Surgery.eml
7	apmpz-cpiuh.html	Radiologic Practice, Year 2019, Issue 11 -New Issue Alert..eml
8	adig0-5yqcw.html	Shanghai Journal of Medical Laboratory Sciences, Year 2019, Issue 11 -New Issue Alert..eml
9	alifh-cayfy.html	Shiyong Pharmacy and Clinical Remedies, Year 2019, Issue 11 -New Issue Alert..eml
10	avxfa-pfx1w.html	The Chinese Journal of Modern Applied Pharmacy, Year 2019, Issue 22 -New Issue Alert..eml

1	abq6i-z4jgq.html	Journal of Cancer Control and Treatment, Year 2019, Issue 11 -New Issue Alert..eml
2	aoo3v-w32d2.html	Journal of Church and State Advance articles.eml
3	a0zop-pnqxy.html	Journal of Clinical Dermatology, Year 2019, Issue 12 -New Issue Alert..eml
4	an41z-3ap6l.html	Journal of Clinical Emergency Call, Year 2019, Issue 12 -New Issue Alert..eml
5	ako4o-cld0n.html	Journal of International Pathology and Clinical Medicine, Year 2019, Issue 11 -New Issue Alert..eml
6	a3in4-5vvrm.html	Journal of Navy Medicine, Year 2019, Issue 06 -New Issue Alert..eml
7	amp0f-fq4kj.html	Journal of Oral and Maxillofacial Surgery, Year 2019, Issue 05 -New Issue Alert..eml
8	aoah7-ftps2.html	Journal of Practical Diagnosis and Therapy, Year 2019, Issue 11 -New Issue Alert..eml
9	a61af-uemqx.html	Journal of Ultrasound in Clinical Medicine, Year 2019, Issue 11 -New Issue Alert..eml
10	a0de0-icsmy.html	Laboratory Medicine, Year 2019, Issue 11 -New Issue Alert..eml
11	aa8q5-vujp1.html	Liaoning Pharmacy and Clinical Remedies, Year 2019, Issue 11 -New Issue Alert..eml

1	ajgkt-wxajd.html	Chinese Journal of Physical Medicine and Rehabilitation, Year 2019, Issue 11 -New Issue Alert..eml
2	a9gzy-fhp6g.html	Chinese Journal of Radiation Oncology, Year 2019, Issue 12 -New Issue Alert..eml
3	apwn0-hr7vu.html	Chinese Journal of Stereotactic and Functional Neurosurgery, Year 2019, Issue 03 -New Issue Alert..eml
4	a1s8p-nfovk.html	Chinese Medicinal Biotechnology, Year 2019, Issue 06 -New Issue Alert..eml
5	awvmv-4elxx.html	Early View Alert_ Contact Dermatitis.eml
6	a70vj-iqb72.html	Featured Videos of 2019.eml
7	aexj8-g5dnp.html	Food and Drug, Year 2019, Issue 05 -New Issue Alert..eml
8	aku3p-kiv1t.html	Herald of Medicine, Year 2019, Issue 12 -New Issue Alert..eml
9	amxnk-vw4co.html	History Workshop Journal Advance articles.eml
10	acccj-6wy5g.html	Imam J Appl Sci – New issue online.eml
11	a9oup-zsvrh.html	International Journal of Ophthalmology, Year 2019, Issue 12 -New Issue Alert..eml

1	avzkc-ddudd.html	Accepted Articles Alert_ Contact Dermatitis.eml
2	anlp7-dxasi.html	Chinese Clinical Oncology, Year 2019, Issue 11 -New Issue Alert..eml
3	azrew-w77s8.html	Chinese Journal of Neuroanatomy, Year 2019, Issue 06 -New Issue Alert..eml
4	ahvr7-88wos.html	Chinese Journal of Neurology, Year 2019, Issue 12 -New Issue Alert..eml
5	a2mu4-1cded.html	Chinese Journal of New Drugs, Year 2019, Issue 23 -New Issue Alert..eml
6	ajnjx-m85c5.html	Chinese Journal of Nuclear Medicine, Year 2019, Issue 11 -New Issue Alert..eml
7	afvyy-rkzz3.html	Chinese Journal of Ophthalmology and otorhinolaryngology, Year 2019, Issue 06 -New Issue Alert..eml
8	a381f-xwuh6.html	Chinese Journal of Optometry & Ophthalmology, Year 2019, Issue 11 -New Issue Alert..eml
9	a1ydn-ouei1.html	Chinese Journal of Otorhinolaryngology Head and Neck Surgery, Year 2019, Issue 11 -New Issue Alert..eml
10	agzmc-o0rr5.html	Chinese Journal of Otorhinolaryngology, Year 2019, Issue 11 -New Issue Alert..eml
11	aamcv-hjdym.html	Chinese Journal of Pathology, Year 2019, Issue 12 -New Issue Alert..eml

1	a4w1q-i8zw7.html	Biomedical and Environmental Sciences, Year 2019, Issue 11 -New Issue Alert..eml
2	alk80-dn1ki.html	Biomedical Engineering and Clinical Medicine, Year 2019, Issue 06 -New Issue Alert..eml
3	asl0m-9nxpf.html	China Food Drug Administration, Year 2019, Issue 10 -New Issue Alert..eml
4	amkcb-xxqfj.html	China Oncology, Year 2019, Issue 10 -New Issue Alert..eml
5	afqsd-pnji2.html	Chinese Clinical Oncology, Year 2019, Issue 11 -New Issue Alert..eml
6	Conversion Failed	Chinese Journal of Cancer Prevention and Treatment, Year 2019, Issue 21 -New Issue Alert..eml
7	Conversion Failed	Chinese Journal of Hospital Pharmacy, Year 2019, Issue 23 -New Issue Alert..eml
8	Conversion Failed	Chinese Journal of Medical Imaging, Year 2019, Issue 11 -New Issue Alert..eml
9	Conversion Failed	Chinese Journal of Medical Ultrasound(Electronic Version), Year 2019, Issue 09 -New Issue Alert..eml
10	Conversion Failed	Chinese Journal of Natural Medicines, Year 2019, Issue 11 -New Issue Alert..eml
11	Conversion Failed	Chinese Journal of Nervous and Mental Diseases, Year 2019, Issue 10 -New Issue Alert..eml

1acq4i-oqp0t.htmlNervous Diseases and Mental Hygiene, Year 2019, Issue 08 -New Issue Alert..eml
2aql52-x8l56.htmlMinds and Machines, Vol. 29, Issue 4 – New Issue Alert.eml
3an6t1-0lovu.htmlLiaoning Pharmacy and Clinical Remedies, Year 2019, Issue 11 -New Issue Alert..eml
4a2th3-30mlz.htmlLaboratory Medicine, Year 2019, Issue 11 -New Issue Alert..eml
5ahumr-t7e75.htmlJournal of Ultrasound in Clinical Medicine, Year 2019, Issue 11 -New Issue Alert..eml
6afmc8-ne39c.htmlJournal of Practical Diagnosis and Therapy, Year 2019, Issue 11 -New Issue Alert..eml
7alvft-y73qr.htmlJournal of Oral and Maxillofacial Surgery, Year 2019, Issue 05 -New Issue Alert..eml
8ae0ed-0gho7.htmlJournal of Navy Medicine, Year 2019, Issue 06 -New Issue Alert..eml
9a3l56-e29fi.htmlJournal of International Pathology and Clinical Medicine, Year 2019, Issue 11 -New Issue Alert..eml
10ab964-3b8co.htmlJournal of Clinical Emergency Call, Year 2019, Issue 12 -New Issue Alert..eml
11awthq-2b751.htmlJournal of Clinical Dermatology, Year 2019, Issue 12 -New Issue Alert..eml

1	a6or7-iq8ac.html	West China Journal of Stomatology, Year 2019, Issue 06 -New Issue Alert..eml
3	a3cbp-txive.html	The Chinese Journal of Modern Applied Pharmacy, Year 2019, Issue 22 -New Issue Alert..eml
4	azjt0-e61rx.html	Shiyong Pharmacy and Clinical Remedies, Year 2019, Issue 11 -New Issue Alert..eml
5	awm8a-vhn8l.html	Shanghai Journal of Medical Laboratory Sciences, Year 2019, Issue 11 -New Issue Alert..eml
7	aqcfw-3d0e9.html	Radiologic Practice, Year 2019, Issue 11 -New Issue Alert..eml
8	a0wcp-bb59m.html	PAP Alert – Dermatologic Surgery.eml
9	ait5x-1x41i.html	Ophthalmology in China, Year 2019, Issue 05 -New Issue Alert..eml
10	a6524-q63c0.html	New articles available for Integrative Cancer Therapies.eml
11	a8b63-r5xdn.html	New articles available for Clinical Medicine Insights_ Case Reports.eml

Journals

1 asmi7-empe7.pdf

intitle_IMMUNOTHERAPY – νέα αποτελέσματα.eml

2 aod74-t1wg6.pdf

intitle_melanoma – νέα αποτελέσματα.eml

3 arxzi-b6pcf.pdf

intitle_OLFACTION – νέα αποτελέσματα.eml

4 am15s-dfm50.pdf

intitle_rhinoSINUSitis – νέα αποτελέσματα.eml

5 arilx-xrwa7.pdf

intitle_VESTIBULE – νέα αποτελέσματα.eml

6 ajsxr-hdjf7.pdf

JOM, Vol. 72, Issue 1 – New Issue Alert.eml

7 aoojg-bwo1m.pdf

Journal of Environmental Sciences _ Volume 89.eml

8 akpv5-70i49.pdf

Journal of Voice Articles in Press E-mail Alert – December 29, 2019.eml

9 a8i7g-d9zgg.pdf

mechanoeletrical transduction of sound – νέα αποτελέσματα.eml

10 aizka-1zdlr.pdf

Medicine in Art – νέα αποτελέσματα.eml

11 aigt9-25h3o.pdf

Mimicking Carcinoma Larynx – νέα αποτελέσματα.eml

1 a0s37-e2zvm.pdf

Nasopharyngeal stenosis – νέα αποτελέσματα.eml

2 aa3eh-sgar2.pdf

Neuro-Oncology Advance articles.eml

3 am1o4-pel9h.pdf

Osteoneogenesis for bone intitle_reconstruction – νέα αποτελέσματα.eml

4 a5pqp-u8czc.pdf

Pakistan Journal of Biological Sciences – Current Issue.eml

5 abp9a-kmqfq.pdf

Pediatric intitle__head and neck_ tumors – νέα αποτελέσματα.eml

6 aiano-3ps6e.pdf

phototherapies – νέα αποτελέσματα.eml

7 ar17u-ufyqx.pdf

plasmonic photothermal intitle_nanoparticles – νέα αποτελέσματα.eml

8 ax3sw-cwme5.pdf

Pneumonia_ 5 Question Quiz.eml

9 afns2-07ely.pdf

protein replacement therapies – νέα αποτελέσματα.eml

10 at433-sx3vt.pdf

Tetrazine‐Based Metal‐Organic Frameworks as Scaffolds for Post‐Synthetic Modification.eml

11 a1c17-j9s47.pdf

The British Journal of Aesthetics Advance articles.eml

1 a5b4k-41cfg.pdf

The Lancet Oncology December Issue Available Online Now.eml

2 anne7-j6935.pdf

Underwater and Hyperbaric Medicine – νέα αποτελέσματα.eml

3 awvh6-t87a8.pdf

Πρωτοχρονιά στο Βερολίνο.eml

1 aciw7-lz2xo.pdf

intitle__hearing loss_ – νέα αποτελέσματα.eml

2 az0dg-hs42i.pdf

intitle__human papillomavirus (HPV_ – νέα αποτελέσματα.eml

3 a0a07-quo34.pdf

intitle__INNER EAR_ – νέα αποτελέσματα.eml

4 a49jh-uncz7.pdf

intitle__ORAL CANCER_ – νέα αποτελέσματα.eml

5 av8n4-fq7ng.pdf

intitle__ORAL DISEASES_ – νέα αποτελέσματα.eml

6 ats8w-sjmln.pdf

intitle__squamous cell carcinoma_ – νέα αποτελέσματα.eml

7 ac013-k9joc.pdf

intitle__thyroid cancer_ surgery – νέα αποτελέσματα.eml

8 aqzai-gga63.pdf

intitle_ALLERGY – νέα αποτελέσματα.eml

9 avzon-g54i9.pdf

intitle_carcinogenesis – new results.eml

10 a4kvm-n9dsz.pdf

intitle_COCHLEA – νέα αποτελέσματα.eml

11 ac42s-k53g7.pdf

intitle_IMMUNOLOGY – νέα αποτελέσματα.eml

1 ayzvt-x8ndd.pdf

hearing – νέα αποτελέσματα.eml

2 a71te-qu7gi.pdf

Infrasound therapies – νέα αποτελέσματα.eml

3 ammzq-brfhj.pdf

International Immunology Advance articles.eml

4 au0vk-1bq3v.pdf

intitle__AUDITORY CORTEX_ – νέα αποτελέσματα.eml

5 a9nie-gcx02.pdf

intitle__ear canal_ – νέα αποτελέσματα.eml

6 amzam-1nepc.pdf

intitle__Epstein-Barr virus_ – νέα αποτελέσματα.eml

7 aob0z-rth6c.pdf

intitle__EUSTACHIAN TUBE_ – νέα αποτελέσματα.eml

8 a3ze1-jtfne.pdf

intitle__Fabry Disease_ ,Hearing Loss – νέα αποτελέσματα.eml

9 a9dau-iz2ly.pdf

intitle__Head and neck cancer_ – νέα αποτελέσματα.eml

10 a3pqc-zpzw6.pdf

intitle__HEAD AND NECK_ TUMORS chemotherapy – νέα αποτελέσματα.eml

11 asn32-jer9k.pdf

intitle__HEAD AND NECK_ – νέα αποτελέσματα.eml

1 au399-5mjz3.pdf

cochlear and intitle__middle ear_ implants – νέα αποτελέσματα.eml

2 atjl1-y9hir.pdf

cosmetic injection of _autologous fat_ – νέα αποτελέσματα.eml

3 anjme-xadhn.pdf

DRUGS intitle_immunotherapy – νέα αποτελέσματα.eml

4 a90h5-d50gh.pdf

eardrum, intitle__tympanic membrane_ – νέα αποτελέσματα.eml

5 a9iyi-ojdb2.pdf

Early View Alert_ Pediatric Dermatology.eml

6 a0i5k-pjszc.pdf

Early View Alert_ Photochemistry and Photobiology.eml

7 azamf-bhvzw.pdf

Early View Alert_ Pigment Cell & Melanoma Research.eml

8 aevo9-gga2s.pdf

ENT Lasers,ORL LASERS – νέα αποτελέσματα.eml

9 aykod-ilxqv.pdf

Functional Imaging in _Chronic Migraine_ – νέα αποτελέσματα.eml

10 aspjr-sgxo7.pdf

Head & _Neck Surgery_ – νέα αποτελέσματα.eml

11 a5d1i-j7fza.pdf

head and neck Fat emboli – νέα αποτελέσματα.eml

1 afq82-0sc5l.pdf

_TASTE,SMELL_ – νέα αποτελέσματα.eml

2 ampsv-j3r0w.pdf

_utricle and saccule_ – νέα αποτελέσματα.eml

3 azq1z-tkoq2.pdf

Ablation of the Thyroid,thyroid,parathyroids – νέα αποτελέσματα.eml

4 alubf-f3ip0.pdf

Accepted Articles Alert_ Photochemistry and Photobiology.eml

5 ahb29-n5iwn.pdf

allintitle_ Head Neck – νέα αποτελέσματα.eml

6 az37a-fkumx.pdf

ALTERNATIVE MEDICINE ON intitle__HEAD AND NECK … – νέα αποτελέσματα.eml

7 a9k5z-w3h3f.pdf

atomistic futility of contemporary civilization – νέα αποτελέσματα.eml

8 ad2qb-2weft.pdf

auditory _Go_NoGo task_ – νέα αποτελέσματα.eml

9 ar61w-kg9co.pdf

Best of JAMA Network 2019.eml

10 ao3bx-d466m.pdf

Biologically Engineered Cochlea – νέα αποτελέσματα.eml

11 ai8pe-5k6m2.pdf

Bronchial foreign bodies – νέα αποτελέσματα.eml

1 a1p3x-1hugk.html

_anterior ethmoid_ artery bleeding – νέα αποτελέσματα.eml

2 a3pto-q8ycx.html

_Ayurvedic medicine_ – νέα αποτελέσματα.eml

3 a2lpf-y74fv.html

_Behcet disease_ as a cause of hearing loss – νέα αποτελέσματα.eml

4 a7fkj-v8qn2.html

_Chinese Medicine_ – νέα αποτελέσματα.eml

5 afiy9-sm6j0.html

_columnar cells_ – νέα αποτελέσματα.eml

6 anymp-r1nga.html

_Department of Otolaryngology_ – νέα αποτελέσματα.eml

7 axtrw-8g0vm.html

_low-frequency_ sound’s therapies – νέα αποτελέσματα.eml

8 acg0f-d5dab.html

_motor-evoked potentials_ – νέα αποτελέσματα.eml

9 a6f46-kimcy.html

_Multimodal Therapy_ – νέα αποτελέσματα.eml

10 aiikp-9pux8.html

_Protruding ears_ – νέα αποτελέσματα.eml

11 alued-c1q6l.html

_selective neck_ treatment – νέα αποτελέσματα.eml

70 Journals for Dec 28th.2019

Journals

1	apfrr-gsv90.html	Read the latest The Journal of Strength & Conditioning Research – Vol. 34, No. 1, January 2020.eml
2	abkgt-ly7fd.html	Read the latest Transplantation – Vol. 104, No. 1, January 2020.eml
3	apouu-64ym7.html	Reminder_ Get End-of-Year CME with JAMA Otolaryngology Clinical Challenges.eml
4	ao6rp-sw2mv.html	Saudi Endod J – New issue online.eml
5	avesw-7q3zd.html	Scan Blog_ Investigation Following Moffitt Departures, NSF Nominee May Boost White House Ties, more.eml
6	ag1ol-0gxo1.html	Selectas siicsalud Medicina Interna, Ed.949.eml
7	azueg-w7u4f.html	Severity of autism symptoms varies greatly among identical twins.eml
8	a7y59-d6yjv.html	Table of Contents Alert_ Journal of Surgical Oncology, Vol. 121, No. 1, January 1, 2020.eml
9	aben6-ya7o3.html	The Philosophical Quarterly Advance articles.eml
10	az5su-dg98r.html	The World Bank Economic Review Advance articles.eml
11	akfww-43bp2.html	Twitter Top News from NCI.eml

1	aaed0-wzwgy.html	Past & Present Advance articles.eml
2	a15bp-j50ey.html	Pediatrics eFirst 27 Dec 2019.eml
3	att1i-rw1wg.html	Prevent Flu with Vaccine and Preventive Actions.eml
4	ay7kn-f9955.html	Read the latest AJN The American Journal of Nursing – Vol. 120, No. 1, January 2020.eml
5	aefcl-cwzqa.html	Read the latest Chinese Medical Journal – Vol. 132, No. 24, December 20, 2019.eml
6	a1fa6-dgl5l.html	Read the latest Critical Care Explorations – Vol. 1, No. 12, December 2019.eml
7	a0wkp-skqf8.html	Read the latest Ear and Hearing – Vol. 41, No. 1, January_February 2020.eml
8	abvrr-xljkn.html	Read the latest IJS Short Reports – Vol. 4, No. 1, October-December 2019.eml
9	ajdom-l51g7.html	Read the latest JBJS Open Access – Vol. 4, No. 4, October-December 2019.eml
10	an3np-iklm1.html	Read the latest Journal of Developmental & Behavioral Pediatrics – Vol. 41, No. 1, January 2020.eml
11	a2yp4-ytxw2.html	Read the latest Psychosomatic Medicine – Vol. 82, No. 1, January 2020.eml

1	any8a-rpsjw.html	Most Read Cancer Currents Posts of 2019.eml
2	a0hae-oyieh.html	New In Chronic Rhinosinusitis With Nasal Polyps.eml
3	arikp-mzm08.html	Now Online_ European Journal of Cancer December Digital Issue.eml
4	a62bh-sni72.html	Occupational Health Science, Vol. 3, Issue 4 – New Issue Alert.eml
5	axjxu-s1qq4.html	Oncol J India – New issue online.eml
6	a5hgu-9hk5p.html	Online First Alert – Transplantation.eml
7	a801g-8vtdf.html	Our latest articles are online and ready to read!.eml
8	alzli-v16xf.html	Palaeogeography, Palaeoclimatology, Palaeoecology _ Volume 538.eml
9	ali2c-yzecp.html	PAP Alert – Anesthesia & Analgesia.eml
10	azlww-9xlb0.html	PAP Alert – Medicine & Science in Sports & Exercise.eml
11	agl5f-chgqt.html	PAP Alert – Shock.eml

1	a3ewx-p7u2p.html	J Nurs Midwifery Sci – New issue online.eml
2	au8bk-3nbkv.html	J Res Pharm Pract – New issue online.eml
3	avxeu-0hcjq.html	JAMA Online First.eml
4	a4djf-5vvz6.html	Journal of Functional Foods _ Volume 64.eml
5	aqad0-lwkr0.html	Journal of Human Evolution _ Volume 138.eml
6	atckq-pi1uw.html	Journal of Oral and Maxillofacial Surgery _ Volume 78, Issue 1.eml
7	ay7ok-uc9w7.html	Journal of Oral and Maxillofacial Surgery_ January 2020 (Volume 78, Issue 1).eml
8	ap6vc-ht1ks.html	Journal of Voice Articles in Press E-mail Alert – December 27, 2019.eml
9	a5db6-ep1xw.html	Journal of Voice Articles in Press E-mail Alert – December 28, 2019.eml
10	a66h5-g1db6.html	Literature and Theology Advance articles.eml
11	amr3n-hvg0p.html	Mind Advance articles.eml

1	a3t3i-h5a9a.html	Critical Criminology, Vol. 27, Issue 4 – New Issue Alert.eml
2	amvm9-g5s9l.html	Daily News_ Qiagen Completes Strategic Review, Rejects Acquisition Offers.eml
3	am8hs-v8iuo.html	Early View Alert_ Journal of Surgical Oncology.eml
4	aoz1c-ojw9o.html	Early View Alert_ Microsurgery.eml
5	aof98-oo2z0.html	Early View Alert_ Mycoses.eml
6	a9vug-lv1my.html	Early View Alert_ The Laryngoscope.eml
7	a55yv-pgrmb.html	EHR Data Reveals Racial Disparities in Emergency Pain Treatment _ Newsletter.eml
8	a57vn-6gmgi.html	FEMS Microbiology Ecology Advance articles.eml
9	a3n2y-uxw5m.html	Fertil Sci Res – New issue online.eml
10	a4yum-dt6vs.html	International Immunology Advance articles.eml
11	a1u9y-9sktv.html	International Journal of Community Well-Being, Vol. 2, Issue 3 – New Issue Alert.eml

1,ace0n-yadyb.html, Week of December 23 – PHIL Image of the Day.eml
2,a2gp3-tahhk.html World J Colorectal Surg – New issue online.eml
3,ai3x9-7c2oy.html
Zeitschrift für Vergleichende Politikwissenschaft, Vol. 13, Issue 4 – New Issue Alert.eml
4,ajbv8-6121l.html ΜΗΤΕΡΑ – 7η Ημερίδα Παιδοακτινολογίας, 8_2_2020.eml

1	ah645-mttci.html	2019 in review_ From the dramatic to the heartwarming_ 2020 predictions.eml
2	aofaj-gv2d9.html	Acta Oceanologica Sinica, Vol. 38, Issue 12 – New Issue Alert.eml
3	aqa45-v10ig.html	alert for Head Neck Larynx Ears Nose Throat Pharynx Cancer.eml
4	afbuv-l8oaj.html	alert for HEAD NECK.eml
5	ahe9g-zpy2r.html	Applying New Therapies- Chronic Lymphocytic Leukemia.eml
6	asxmh-ptjk8.html	Asian Pac J Trop Med – New issue online.eml
7	a5jwn-yxs65.html	Better Sleep Linked to Reduced CVD, Stroke Risk.eml
8	aq0m8-x8liw.html	Brain Circ – New issue online.eml
9	an3s2-pze2q.html	Cancer Letters _ Volume 471.eml
10	aq129-mqrr8.html	Clinical Infectious Diseases Advance articles.eml
11	a03zb-4561g.html	Clinical Medicine Insights_ Circulatory, Respiratory and Pulmonary Medicine Vol. 13, January-December 2019 is now available online.eml

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com, Telephone consultation 11855 int 1193,

Quantitative Anti-HBc in Liver Pathological States in Patients with Chronic Hepatitis B Virus Infection
Quantitative Anti-HBc in Liver Pathological States in Patients with Chronic Hepatitis B Virus Infection: Background. Changes of hepatitis B core antigen antibody (anti-HBc) in liver pathological involvement in patients with chronic hepatitis B virus (HBV) infection have not been investigated in detail. This study aimed to explore evolving patterns of anti-HBc following liver pathological states and to investigate validities of anti-HBc for predicting liver pathological states. Methods. 254 HBeAg-positive…

Medicine by Alexandros G. Sfakianakis

09:31

A Case of Long-Term Survival after Checkpoint Inhibitor Pneumonitis in a Patient with Squamous Cell Lung Cancer
A Case of Long-Term Survival after Checkpoint Inhibitor Pneumonitis in a Patient with Squamous Cell Lung Cancer: The management of grade 1 checkpoint inhibitor pneumonitis (CIP) is to withhold immune checkpoint inhibitors; however, the natural history of this condition is unknown. We herein report the case of a woman with squamous cell lung cancer who was a long-term survivor after CIP. After 4 rounds of treatment with nivolumab, a chest CT revealed a reticular pattern and ground-glass attenuation…

Medicine by Alexandros G. Sfakianakis

09:31

The Impact of Physicians’ Working Hours on Inappropriate Use of Outpatient Medicine in a Tertiary Hospital
The Impact of Physicians’ Working Hours on Inappropriate Use of Outpatient Medicine in a Tertiary Hospital in China: AbstractBackgroundInappropriate prescribing is an important health system problem in China. Several studies have identified critical factors influencing prescription quality, but the impact of physicians’ working hours remains unknown. In China, tertiary hospitals face ever-increasing outpatient volumes. Physicians are asked to work long hours and the impact of shift duration on prescription…

Medicine by Alexandros G. Sfakianakis

09:31

iFuse Implant System for Treating Chronic Sacroiliac Joint Pain: A NICE Medical Technology Guidance
iFuse Implant System for Treating Chronic Sacroiliac Joint Pain: A NICE Medical Technology Guidance: AbstractTreatment and management of sacroiliac joint pain is often non-surgical, involving packages of care that can include analgesics, physiotherapy, corticosteroid injections and radiofrequency ablation. Surgical intervention is considered when patients no longer respond to conservative management. The iFuse Implant System is placed across the sacroiliac joint using minimally invasive surgery,…

Medicine by Alexandros G. Sfakianakis

09:30

Ultra-High-Field 7T MRI in the Study of Intracranial Vascularity
Emerging Use of Ultra-High-Field 7T MRI in the Study of Intracranial Vascularity: State of the Field and Future Directions [REVIEW ARTICLE]: SUMMARY:Cerebrovascular disease is a major source of mortality that commonly requires neurosurgical intervention. MR imaging is the preferred technique for imaging cerebrovascular structures, as well as regions of pathology that include microbleeds and ischemia. Advanced MR imaging sequences such as time-of-flight, susceptibility-weighted imaging, and 3D T2-weighted…

Medicine by Alexandros G. Sfakianakis

09:30

Intra-Arterial Verapamil Treatment in Oral Therapy-Refractory Reversible Cerebral Vasoconstriction Syndrome
Intra-Arterial Verapamil Treatment in Oral Therapy-Refractory Reversible Cerebral Vasoconstriction Syndrome [INTERVENTIONAL]: SUMMARY:Reversible vasoconstriction syndrome is a complex of clinical symptoms and angiographic findings, which, while having a mostly benign clinical course, has clinical and imaging overlap with more serious disorders such as vasculitis and aneurysmal SAH and itself includes a minority of patients with fulminant vasoconstriction resulting in severe intracranial complications….

Medicine by Alexandros G. Sfakianakis

09:29

Metal Artifact Reduction in Head CT Performed for Patients with Deep Brain Stimulation Devices: Effectiveness of a Single-Energy Metal Artifact Reduction Algorithm [ADULT BRAIN]
Metal Artifact Reduction in Head CT Performed for Patients with Deep Brain Stimulation Devices: Effectiveness of a Single-Energy Metal Artifact Reduction Algorithm [ADULT BRAIN]: BACKGROUND AND PURPOSE:Deep brain stimulation electrodes induce massive artifacts on CT images, deteriorating the diagnostic value of examinations. We aimed to investigate the usefulness and potential limitations of a single-energy metal artifact reduction algorithm in head CT performed in patients with implanted deep brain…

Medicine by Alexandros G. Sfakianakis

09:29

Characterization of Carotid Plaque Components by Quantitative Susceptibility Mapping [EXTRACRANIAL VASCULAR]
Characterization of Carotid Plaque Components by Quantitative Susceptibility Mapping [EXTRACRANIAL VASCULAR]: BACKGROUND AND PURPOSE:Intraplaque hemorrhage in the carotid artery is related to an increased risk of cerebrovascular ischemic events. We aimed to investigate whether quantitative susceptibility mapping can characterize carotid artery plaque components and quantify the severity of intraplaque hemorrhage.MATERIALS AND METHODS:For this ex vivo quantitative susceptibility mapping study, 9 carotid…

Medicine by Alexandros G. Sfakianakis

09:29

The use and cost‐effectiveness of intraoperative navigation in pediatric sinus surgery
The use and cost‐effectiveness of intraoperative navigation in pediatric sinus surgery: Objectives/HypothesisThere are consensus statements about when to use intraoperative navigation (IN) in adult sinus surgery. However, no corresponding guidelines exist for pediatrics. Our objectives included: 1) assess the demographic and operative factors associated with IN use and 2) calculate the cost‐effectiveness of IN use.Study DesignRetrospective chart review.MethodsOne hundred nineteen pediatric patients…

Medicine by Alexandros G. Sfakianakis

09:28

Relationship of Overall Cardiovascular Health and Hearing Loss in The Jackson Heart Study Population
Relationship of Overall Cardiovascular Health and Hearing Loss in The Jackson Heart Study Population: ObjectivesTo evaluate the relationships among the overall cardiovascular health scoring tool, Life’s Simple 7 (LS7), and hearing in an African‐American cardiovascular study cohort.MethodsUsing the Jackson Heart Study’s cohort of African Americans, the relationships between the LS7 scoring metric and hearing of 1314 individuals were assessed. Standard audiometric data was collected and hearing loss…

Medicine by Alexandros G. Sfakianakis

09:28

Does 3D volumetric analysis predict the reach of endoscopically harvested buccal fat pad flap
Does 3D volumetric analysis predict the reach of endoscopically harvested buccal fat pad flap: ObjectivesTo determine if the volume of buccal fat, ascertained by computed tomography (CT) scanning, would correspond to surface area and reach (length and width) of the flap intraoperatively to aid in the reconstruction of selected skull base defects.MethodsCadaveric study of five specimens, 10 sides. Methods CT imaging and evaluation using the Osirix 9 software (Pixmeo; Bernex, Switzerland). of cadaveric…

Medicine by Alexandros G. Sfakianakis

09:28

Age-Related Hyperglycemia as a Cause of Increased Cancer Incidence
Age-Related Hyperglycemia as a Cause of Increased Cancer Incidence: Why is cancer an age-related condition? One can propose a range of mechanisms: the spread of stochastic DNA damage through cell populations; rising levels of chronic inflammation; ever more senescent cells turning out disruptive, pro-growth signals; the growing inability of the immune system to promptly destroy errant cells. The authors of this open access paper argue that the metabolic dysfunction of later life that leads to raised…

Medicine by Alexandros G. Sfakianakis

09:27

Eosinophilic esophagitis: A new food-related allergic condition on the rise?
Eosinophilic esophagitis: A new food-related allergic condition on the rise?: In the early 1990s, doctors began describing a new condition affecting the esophagus of patients who were predisposed to allergies including food allergy, asthma, and eczema, and who were having trouble swallowing. Today, we call this condition eosinophilic esophagitis (EoE). What is EoE? EoE is an allergic inflammation of the esophagus that causes a range of symptoms. Adolescents and adults most often experience it as…

Medicine by Alexandros G. Sfakianakis

09:27

Surgical tracheostomy in children with malignancy receiving intensive chemotherapy: A case series and review of literature
Surgical tracheostomy in children with malignancy receiving intensive chemotherapy: A case series and review of literature: AbstractWe retrospectively reviewed a paediatric intensive care unit database that supports a tertiary oncology service to explore safety and outcome of tracheostomy in oncology patients over a 12‐year period and reviewed literature. A total of 895 patients were admitted with a haematological or a solid tumour malignancy of which 222 were ventilated. Six of 222 (2.7%) ventilated…

Medicine by Alexandros G. Sfakianakis

09:26

Thermal ablation for hepatocellular carcinoma: what’s new in 2019
Thermal ablation for hepatocellular carcinoma: what’s new in 2019: Hepatocellular carcinoma (HCC) is the sixth most common cancer worldwide, but a major proportion of patients are not appropriate candidates for surgical resection or transplantation. For this reason, image-guided tumor ablation using thermal energy for early-stage HCC has become an accepted curative treatment option in all HCC treatment guidelines due to its minimal invasiveness and proven outcomes. In recent years, microwave ablation…

Medicine by Alexandros G. Sfakianakis

09:26

Mucoid and coccoid Helicobacter pylori with fast growth and antibiotic resistance
Mucoid and coccoid Helicobacter pylori with fast growth and antibiotic resistance: AbstractBackgroundIn this study, one Helicobacter pylori isolate, from gastric biopsy of a dyspeptic patient that turned into mucoid‐coccoid (MC) form upon consecutive subcultures, was identified. The culturability, antibiotic resistance, and lipid contents of MC were compared with those of non‐mucoid (NM) spiral H pylori.Materials and MethodsMucoid‐coccoid and NM H pylori were subcultured on Brucella blood agar (BBA)…

Medicine by Alexandros G. Sfakianakis

09:26

BCOR‐CCNB3 fusion‐positive clear cell sarcoma of the kidney
BCOR‐CCNB3 fusion‐positive clear cell sarcoma of the kidney: AbstractClear cell sarcoma of the kidney (CCSK) is the second most common malignant pediatric renal tumor. Two of the recurrent somatic alterations reported in CCSK are BCL‐6 corepressor (BCOR) internal tandem duplication (ITD) and YWHAE‐NUTM2B/E gene fusion. A minority of patients with CCSKs have other rare somatic alterations. We report two patients with CCSK showing BCOR‐CCNB3 (where CCNB3 is cyclin B3) fusion, who had similar clinical…

Medicine by Alexandros G. Sfakianakis

09:26

The effect of graft‐versus‐host disease on outcomes after allogeneic stem cell transplantation for refractory lymphoblastic lymphoma in children and young adults
The effect of graft‐versus‐host disease on outcomes after allogeneic stem cell transplantation for refractory lymphoblastic lymphoma in children and young adults: AbstractBackgroundPatients with relapsed or refractory lymphoblastic lymphoma (LBL) have a poor prognosis. The efficacy of allogeneic blood stem cell transplantation for treatment of this disease remains unclear in terms of transplantation‐related toxicity. Acute and chronic graft‐versus‐host diseases (GVHD) are both harmful to patients…

Medicine by Alexandros G. Sfakianakis

09:25

The Therapeutic Effect of Nordic Walking on Freezing of Gait in Parkinson’s Disease: A Pilot Study
The Therapeutic Effect of Nordic Walking on Freezing of Gait in Parkinson’s Disease: A Pilot Study: Introduction. The effectiveness of the currently utilized therapies for FoG is limited. Several studies demonstrated a beneficial impact of Nordic walking (NW) on several gait parameters in Parkinson’s disease, but only one paper reported reduction of freezing. Research Question. In the present study, the question is whether NW is an effective therapeutic intervention in FoG. Methods. Twenty PD subjects…

Medicine by Alexandros G. Sfakianakis

09:25

Incidental Anomalous Left Coronary Artery in a Transplanted Heart
Incidental Anomalous Left Coronary Artery in a Transplanted Heart: Anomalous coronary artery is an uncommon congenital cardiac anomaly that is often detected incidentally on coronary angiography. It has rarely been reported in the donor heart of patients who have undergone cardiac transplantation. Here, we report a case of a 72-year-old patient who received a second heart transplant and has been identified to have an anomalous left main coronary artery originating from the right coronary sinus on…

Medicine by Alexandros G. Sfakianakis

09:19

Mapping the Human Exposome to Uncover the Causes of Breast Cancer
IJERPH, Vol. 17, Pages 189: Mapping the Human Exposome to Uncover the Causes of Breast Cancer: IJERPH, Vol. 17, Pages 189: Mapping the Human Exposome to Uncover the Causes of Breast CancerInternational Journal of Environmental Research and Public Health doi: 10.3390/ijerph17010189Authors: Vincent Bessonneau Ruthann A. Rudel Breast cancer is an important cause of morbidity and mortality for women, yet a significant proportion of variation in individual risk is unexplained. It is reasonable to…

Medicine by Alexandros G. Sfakianakis

09:19

Chronic Disseminated Candidiasis During Hematological Maligancies: An Immune Reconstitution Inflammatory Syndrome with Expansion of Pathogen-Specific TH1 T Cells
Chronic Disseminated Candidiasis During Hematological Maligancies: An Immune Reconstitution Inflammatory Syndrome with Expansion of Pathogen-Specific TH1 T Cells: AbstractChronic disseminated candidiasis (CDC) is a rare disease mostly occurring after chemotherapy-induced prolonged neutropenia in patients with hematological malignancies. It is believed to ensue from Candida colonization, breach of the intestinal epithelial barrier and venous translocation to organs. Fungal blood or liver biopsy cultures…

Medicine by Alexandros G. Sfakianakis

09:18

Screening Strategies for a Sustainable Endpoint for Gambiense Sleeping Sickness
Screening Strategies for a Sustainable Endpoint for Gambiense Sleeping Sickness: AbstractBackgroundGambiense human African trypanosomiasis ([gHAT] sleeping sickness) is a vector-borne disease that is typically fatal without treatment. Intensified, mainly medical-based, interventions in endemic areas have reduced the occurrence of gHAT to historically low levels. However, persistent regions, primarily in the Democratic Republic of Congo (DRC), remain a challenge to achieving the World Health Organization’s…

Medicine by Alexandros G. Sfakianakis

09:18

Development and application of a microplate assay for toxicity testing on aquatic cyanobacteria
Development and application of a microplate assay for toxicity testing on aquatic cyanobacteria: AbstractRegulatory environmental risk assessment (ERA), applied to establish a protection limit for all bacterial diversity in surface waters, relies on a growth inhibition test performed upon a single species of cyanobacteria and the activated sludge respiration inhibition test (ASRIT). Recently, the ability of this approach to protect adequately for bacteria that provide important ecosystem services…

Medicine by Alexandros G. Sfakianakis

09:17

36 heavy metal analysis and health risk assessment in aerosol : Ca > Fe > Mg > Al > K > Na > Zn > P > Ba > Ti > Cu > Sr > B > Sn > I > V > Rb > Ce > Mo > Cs > Th > Ag > U > Pt
Chemical content and source apportionment of 36 heavy metal analysis and health risk assessment in aerosol of Beijing: AbstractThe concentration levels of 36 airborne heavy metals and atmospheric radioactivity in total suspended particulate (TSP) samples were measured to investigate the chemical characteristics, potential sources of aerosols, and health risk in Beijing, China, from September 2016 to September 2017. The TSP concentrations varied from 6.93 to 469.18 μg/m3, with a median of 133.97 μg/m3….

Medicine by Alexandros G. Sfakianakis

09:16

Thin-layer fine-sand capping of polluted sediments decreases nutrients in overlying water
Thin-layer fine-sand capping of polluted sediments decreases nutrients in overlying water of Wuhan Donghu Lake in China: AbstractCapping water body sediments with a thin layer of sand is an effective technique to decrease nutrient concentrations in the water column and accelerate ecological restoration of eutrophic water bodies. However, long-term effects of thin-layer sand capping in shallow lakes are reported less often. Using clean fine sand and geotextile mats as capping materials for sediments…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:15

N2 fixation in urbanization area rivers: spatial-temporal variations and influencing factors
N 2 fixation in urbanization area rivers: spatial-temporal variations and influencing factors: AbstractWhile nitrogen (N2) fixation is an important process in nitrogen (N) biogeochemical cycling, supplying a significant portion of the N in natural ecosystems, few quantitative constraints exist concerning its contribution to the N enrichment and export from river ecosystems. This study estimates the N2 fixation rates of urban rivers in the Yangtze Estuary area using acetylene reduction. The results…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:14

Autophagy and Macrophage Functions: Inflammatory Response and Phagocytosis
Cells, Vol. 9, Pages 70: Autophagy and Macrophage Functions: Inflammatory Response and Phagocytosis: Cells, Vol. 9, Pages 70: Autophagy and Macrophage Functions: Inflammatory Response and PhagocytosisCells doi: 10.3390/cells9010070Authors: Ming-Yue Wu Jia-Hong Lu Autophagy is a conserved bulk degradation and recycling process that plays important roles in multiple biological functions, including inflammatory responses. As an important component of the innate immune system, macrophages are involved…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:14

Growth charts in Kabuki syndrome 1
Growth charts in Kabuki syndrome 1: AbstractKabuki syndrome (KS, KS1: OMIM 147920 and KS2: OMIM 300867) is caused by pathogenic variations in KMT2D or KDM6A. KS is characterized by multiple congenital anomalies and neurodevelopmental disorders. Growth restriction is frequently reported. Here we aimed to create specific growth charts for individuals with KS1, identify parameters used for size prognosis and investigate the impact of growth hormone therapy on adult height. Growth parameters and parental…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:13

Selective ß2-Adrenoceptor Agonists and Relevant Hyperlactatemia
JCM, Vol. 9, Pages 71: Selective ß2-Adrenoceptor Agonists and Relevant Hyperlactatemia: Systematic Review and Meta-Analysis: JCM, Vol. 9, Pages 71: Selective ß2-Adrenoceptor Agonists and Relevant Hyperlactatemia: Systematic Review and Meta-AnalysisJournal of Clinical Medicine doi: 10.3390/jcm9010071Authors: Alina G. Liedtke Sebastiano A. G. Lava Gregorio P. Milani Carlo Agostoni Viola Gilardi Mario G. Bianchetti Giorgio Treglia Pietro B. Faré Selective ß2-agonists have been imputed…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:12

Efficacy of reciprocating and ultrasonic activation of 6% sodium hypochlorite in the reduction of microbial content and virulence factors in teeth with primary endodontic infection
Efficacy of reciprocating and ultrasonic activation of 6% sodium hypochlorite in the reduction of microbial content and virulence factors in teeth with primary endodontic infection: AbstractAimTo evaluate in a clinical trial the efficacy of reciprocating and ultrasonic activation of 6% sodium hypochlorite (NaOCl) in microbial composition and reduction of microbial load as well as in levels of lipopolysaccharide (LPS) and lipoteichoic acid (LTA) in teeth with primary endodontic infection.MethodologySamples…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:11

Gaint Phyllodes Tumour with Axillary & Interpectoral Lymph Node Metastasis; a Rare Presentation
Gaint Phyllodes Tumour with Axillary & Interpectoral Lymph Node Metastasis; a Rare Presentation: ConclusionManagement of Phyllodes tumor presents the surgeon with challenges. Core tissue biopsy is a reliable method for pre-operative diagnosis. Imaging like CT scan and MRI help to evaluate the primary lesion as well as distant metastasis. The majority of these cases can be managed by simple mastectomy. Axillary lymph node metastasis is rare and dissection should be limited to patients with pathological…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:11

The Application and Analytical Pathway of Dexmedetomidine in Ischemia/Reperfusion Injury
The Application and Analytical Pathway of Dexmedetomidine in Ischemia/Reperfusion Injury: Ischemia/reperfusion cerebral injury can cause serious damage to nerve cells. The injured organelles are cleared by autophagy eventually, which is critical for cell survival. Dexmedetomidine is neuroprotective in various ischemia/reperfusion models. Mitochondrial calcium uniporter (MCU) is the most important channel of mitochondrial Ca2+ influx into mitochondria, where Ca2+ has a potential effect on mitochondrial…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:11

The Effect of Compound Sophora on Fluorouracil and Oxaliplatin Resistance in Colorectal Cancer Cells
The Effect of Compound Sophora on Fluorouracil and Oxaliplatin Resistance in Colorectal Cancer Cells: Fluorouracil (5-FU) and oxaliplatin (L-OHP) are the most commonly used chemotherapy drugs for colorectal cancer, though resistance is common. Compound Sophora injection is a traditional Chinese medicine that can protect the liver against oxidation, improve immunity, and enhance sensitivity to chemotherapy; it may have an effect of reversing resistance in 5-FU- and L-OHP-resistant gastric cancer cells…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:11

Remove ads

Antimicrobial Air Filters Using Natural Sea Salt Particles for Deactivating Airborne Bacterial Particles
IJERPH, Vol. 17, Pages 190: Antimicrobial Air Filters Using Natural Sea Salt Particles for Deactivating Airborne Bacterial Particles: IJERPH, Vol. 17, Pages 190: Antimicrobial Air Filters Using Natural Sea Salt Particles for Deactivating Airborne Bacterial ParticlesInternational Journal of Environmental Research and Public Health doi: 10.3390/ijerph17010190Authors: Sang Bin Jeong Ki Joon Heo Byung Uk Lee We developed an antimicrobial air filter using natural sea salt (NSS) particles. Airborne…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:10

Bone marrow-derived non-transformed murine macrophages with an unlimited self-renewing ability
GSE142619 Bone marrow-derived non-transformed murine macrophages with an unlimited self-renewing ability: Contributors : Hesham Nasser ; Partho Adhikary ; Amira Abdel-Daim ; Osamu Noyori ; Ryusho Kariya ; Seiji Okada ; Wenjuan Ma ; Masaya Baba ; Hitoshi Takizawa ; Mariko Yamane ; Hitoshi Niwa ; Shinya SuzuSeries Type : Expression profiling by arrayOrganism : Tissue macrophages derive from bone marrow monocytes, and recent studies using mice have revealed that they also derive from yolk…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:10

Methylation Profiling of Medulloblastoma in a Clinical Setting Permits Sub-Classification and Reveals New Outcome Predictions
GSE142627 Methylation Profiling of Medulloblastoma in a Clinical Setting Permits Sub-Classification and Reveals New Outcome Predictions: Contributors : Abedalthagafi Malak ; Snuderl MatijaSeries Type : Methylation profiling by arrayOrganism : In this study, we report the first examination of Medulloblastoma (MB) methylation patterns in Arab world, using an extensive primary tumor cohort in tertiray care center. We assessed DNA methylation patterns to sub-classify clinical MB cases and their amenability…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:09

Next-generation sequencing of wild type and 5XFAD transcriptomes for Alzheimer’s disease study
GSE142633 Next-generation sequencing of wild type and 5XFAD transcriptomes for Alzheimer’s disease study: Contributors : Han S Koh ; Jin H Ryu ; Hyun J Cho ; Jae W MinSeries Type : Expression profiling by high throughput sequencingOrganism : We found some novel miRNA that targets SIRT1 may contribute to the pathogenesis in AD mouse model. We first identified that SIRT1 is significantly reduced in Alzheimer patient`s precentral gyrus and 5XFAD mice. To determine whether the strategy of inhibiting…

Medicine by Alexandros G. Sfakianakis

09:00

Changes in the morphology of the triangular fibrocartilage complex (TFCC) on magnetic resonance arthrography related to disruption of ulnar foveal attachment
Changes in the morphology of the triangular fibrocartilage complex (TFCC) on magnetic resonance arthrography related to disruption of ulnar foveal attachment: AbstractObjectiveTo assess whether a proximal ligamentous component (PLC) of the triangular fibrocartilage complex (TFCC) with a distally prolapsing morphology is associated with the presence of a TFCC foveal tear on arthroscopy.MethodsOne-hundred thirty-two patients (134 wrists) who underwent MR arthrography and subsequent wrist arthroscopy…

Medicine by Alexandros G. Sfakianakis

08:59

Opioid Use After Hospital Care due to Hip Fracture Among Community-Dwelling Persons With and Without Alzheimer’s Disease
Opioid Use After Hospital Care due to Hip Fracture Among Community-Dwelling Persons With and Without Alzheimer’s Disease: AbstractBackgroundHip fractures are common among persons with Alzheimer’s disease (AD), but problems in pain assessment may lead to insufficient analgesia after hospitalization.ObjectiveWe investigated the prevalence of opioid use in the 6 months after discharge from hospital care due to hip fracture among community-dwellers with and without AD.Setting and methodThe Medication…

Medicine by Alexandros G. Sfakianakis

08:59

The influence of knee bolster on lumbar spinal stenosis parameters on MR images
The influence of knee bolster on lumbar spinal stenosis parameters on MR images: AbstractObjectiveTo estimate the effect of the knee bolster use during an MRI on lumbar spinal stenosis parameters and low back pain-related disability.MethodsA repeated-measurement study of 27 males and 19 females with mean age 55.78 ± 14.36, referred for an MRI of the lumbar spine due to low back pain, performed with and without standard knee bolster. A radiologist evaluated the lumbar lordosis Cobb’s angle, the cross-sectional…

Medicine by Alexandros G. Sfakianakis

08:59

The ring-shaped meniscus: a case series demonstrating the variation of imaging appearances on MRI
The ring-shaped meniscus: a case series demonstrating the variation of imaging appearances on MRI: AbstractThe ring-shaped meniscus (RSM) is a rare meniscal variant in which there is an intermeniscal bridge between the anterior and posterior horns of the meniscus, thus forming a complete ring. The lateral meniscus is more commonly involved than the medial meniscus. Distinguishing an RSM from a bucket handle tear (BHT) with a displaced fragment in the intercondylar notch is challenging and there are…

Medicine by Alexandros G. Sfakianakis

08:58

Nodal metastases of soft tissue sarcomas: risk factors, imaging findings, and implications
Nodal metastases of soft tissue sarcomas: risk factors, imaging findings, and implications: AbstractSoft tissue sarcomas (STS) are malignancies derived from connective tissue, and regional lymph node metastasis (RLNM), while not common, is an important aspect of prognosis and treatment. Various risk factors, in particular the histological subtype, affect the likelihood of nodal involvement, which can be characterized by imaging features such as nodal dimension and morphology. Currently, surveillance…

Medicine by Alexandros G. Sfakianakis

08:58

A novel technique for retrieval of a broken biopsy needle
A novel technique for retrieval of a broken biopsy needle: AbstractA broken needle is a rare complication of bone biopsy. We describe an easily applied technique of retrieval of a retained biopsy needle fragment using a cannulated drill typically used for internal fixation of femoral neck fractures. This approach allows for removal under moderate conscious sedation and can be performed by a radiologist using fluoroscopic or CT-fluoroscopic guidance in the radiology suite.

Medicine by Alexandros G. Sfakianakis

08:57

Cartilage degeneration post-meniscectomy performed for degenerative disease versus trauma: data from the Osteoarthritis Initiative
Cartilage degeneration post-meniscectomy performed for degenerative disease versus trauma: data from the Osteoarthritis Initiative: AbstractObjectiveTo compare the extent of cartilage deterioration in knees with prior meniscal resection related to trauma versus knees with resection related to degenerative disease, and to compare cartilage deterioration in knees with meniscal surgery to knees without meniscal surgery, controlling for prior knee trauma.Materials and methodsIn this cross-sectional study,…

Medicine by Alexandros G. Sfakianakis

08:57

Lumbosacral plexiform neurofibroma: a rare case in an adult without neurofibromatosis type I
Lumbosacral plexiform neurofibroma: a rare case in an adult without neurofibromatosis type I: AbstractPlexiform neurofibromas are an uncommon variant of neurofibromas that are described as being essentially pathognomonic of neurofibromatosis type 1 (NF1). Plexiform neurofibromas in the absence of NF1 are extremely rare. We present the case of a 38-year-old woman with a large multilobulated lumbosacral mass extending into the pelvis and proximal thigh. Histopathology of a CT-guided biopsy of the mass…

Medicine by Alexandros G. Sfakianakis

08:57

Subsynovial epidermal inclusion cyst of the knee
Subsynovial epidermal inclusion cyst of the knee: AbstractWe report a case of a subsynovial epidermal inclusion cyst in a 47-year-old woman with a painful spontaneous swelling of the right knee and a 2-year history of puncture and arthroscopy. Epidermal inclusion cysts are one of the most common benign subcutaneous tumours. Very rarely, they are located in an articulation and can cause an inflammatory reaction when rupture occurs. Simple surgical excision is the preferred therapy. The main goal of…

Medicine by Alexandros G. Sfakianakis

08:57

The added value of SPECT-CT in the detection of heterotopic ossification on bone scintigraphy
The added value of SPECT-CT in the detection of heterotopic ossification on bone scintigraphy: AbstractPurposeHeterotopic ossification (HO) is the abnormal osteogenesis in non-skeletal tissue. It can be difficult to detect, as it can mimic other conditions clinically and on imaging studies. The purpose of this study was to find the added value of SPECT-CT in accurate detection of HO.Materials and methodsA total of 1780 reports on the PACS system of patients underwent bone scintigraphy at the Department…

Medicine by Alexandros G. Sfakianakis

08:56

Current status and recommendations for imaging in neurofibromatosis type 1, neurofibromatosis type 2, and schwannomatosis
Current status and recommendations for imaging in neurofibromatosis type 1, neurofibromatosis type 2, and schwannomatosis: AbstractNeurofibromatosis type 1 (NF1), neurofibromatosis type 2 (NF2), and schwannomatosis (SWN) are three clinically distinct tumor predisposition syndromes with a shared tendency to develop peripheral and central nervous system neoplasms. Disease expression and complications of NF1, NF2, and SWN are highly variable, necessitating a multidisciplinary approach to care in order…

Medicine by Alexandros G. Sfakianakis

08:56

Current applications and future directions of deep learning in musculoskeletal radiology
Current applications and future directions of deep learning in musculoskeletal radiology: AbstractDeep learning with convolutional neural networks (CNN) is a rapidly advancing subset of artificial intelligence that is ideally suited to solving image-based problems. There are an increasing number of musculoskeletal applications of deep learning, which can be conceptually divided into the categories of lesion detection, classification, segmentation, and non-interpretive tasks. Numerous examples of…

Medicine by Alexandros G. Sfakianakis

08:56

Bone mineral density measurement combined with vertebral fracture assessment increases diagnosis of osteoporosis in postmenopausal women
Bone mineral density measurement combined with vertebral fracture assessment increases diagnosis of osteoporosis in postmenopausal women: AbstractObjectiveOsteoporosis is diagnosed based on the results of BMD assessment and/or fragility fractures. Vertebral fracture is the most common fragility fracture. Many vertebral fractures are asymptomatic and are not clinically recognized. Early detection of vertebral fracture may increase diagnosis of osteoporosis. In this study, we performed BMD measurement…

Medicine by Alexandros G. Sfakianakis

08:54

Clinical utility of a postprocedural CT scan in CT-guided musculoskeletal biopsies
Clinical utility of a postprocedural CT scan in CT-guided musculoskeletal biopsies: AbstractObjectiveThe purpose of this study is first to determine the clinical utility of the postprocedure scan in detecting postinterventional complications after CT-guided musculoskeletal biopsies, and second to evaluate the contribution to the radiation dose of the postprocedural CT scan.Materials and methodsRetrospective analysis of 500 consecutive CT-guided musculoskeletal biopsies over an 18-month period from…

Medicine by Alexandros G. Sfakianakis

08:54

Bone marrow-derived non-transformed murine macrophages with an unlimited self-renewing ability
GSE142619 Bone marrow-derived non-transformed murine macrophages with an unlimited self-renewing ability: Contributors : Hesham Nasser ; Partho Adhikary ; Amira Abdel-Daim ; Osamu Noyori ; Ryusho Kariya ; Seiji Okada ; Wenjuan Ma ; Masaya Baba ; Hitoshi Takizawa ; Mariko Yamane ; Hitoshi Niwa ; Shinya SuzuSeries Type : Expression profiling by arrayOrganism : Mus musculusTissue macrophages derive from bone marrow monocytes, and recent studies using mice have revealed that they also derive…

Medicine by Alexandros G. Sfakianakis

08:54

Chronic inflammation induces epithelial-to-mesenchymal transition memory in non-small cell lung cancer
GSE142620 Chronic inflammation induces epithelial-to-mesenchymal transition memory in non-small cell lung cancer: Contributors : Rui Li ; Stephanie L Ong ; Linh M Tran ; Zhe Jing ; Zhi L Huang ; Bin Liu ; Gina Lee ; Ramin Salehi-Rad ; Kostyantyn Krysan ; Paul C Pagano ; Manash K Paul ; Shili Xu ; Harvey R Herschman ; Steven M DubinettSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensChronic inflammation facilitates tumor development. However, the underlying…

Medicine by Alexandros G. Sfakianakis

08:53

A Zebrafish JAK1-A634D Gain-of-Function Model Provides New Insights into the Pathogenesis of Familial Hypereosinophilia
GSE142599 A Zebrafish JAK1-A634D Gain-of-Function Model Provides New Insights into the Pathogenesis of Familial Hypereosinophilia: Contributors : Anna Cordeiro-Santanach ; Sergey V Prykhozhij ; Adam P Deveau ; Gabriel Wajnberg ; Nicolas Crapoulet ; Stuart E Turvey ; Jason N BermanSeries Type : Expression profiling by high throughput sequencingOrganism : Danio rerioJAK1 plays an important role during zebrafish development as hematopoietic regulator with a specific impact in the myeloid lineage,…

Medicine by Alexandros G. Sfakianakis

08:53

Next-generation sequencing of wild type and 5XFAD transcriptomes for Alzheimer’s disease study
GSE142633 Next-generation sequencing of wild type and 5XFAD transcriptomes for Alzheimer’s disease study: Contributors : Han S Koh ; Jin H Ryu ; Hyun J Cho ; Jae W MinSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusWe found some novel miRNA that targets SIRT1 may contribute to the pathogenesis in AD mouse model. We first identified that SIRT1 is significantly reduced in Alzheimer patient`s precentral gyrus and 5XFAD mice. To determine whether the strategy of…

Medicine by Alexandros G. Sfakianakis

08:53

SUV39H1 regulates human colon carcinoma apoptosis and cell cycle to promote tumor growth
GSE142625 SUV39H1 regulates human colon carcinoma apoptosis and cell cycle to promote tumor growth: Contributors : Chunwan Lu ; John D Klement ; Dafeng Yang ; Thomas Albers ; Iryna O Lebedyeva ; Jennifer L Waller ; Kebin LiuSeries Type : Expression profiling by arrayOrganism : Homo sapiens ; Mus musculusTranscriptional profiling of histone methyltransferase SUV39H1-selective small molecule inhibitor F5446-induced genes in human colon carcinoma cells. Tumor cells were treated with F5446 for 48h…

Medicine by Alexandros G. Sfakianakis

08:52

Single cell RNA sequencing for mouse femoral artery
GSE139827 Single cell RNA sequencing for mouse femoral artery: Contributors : Bin Zhou ; Dong Gao ; Juan Tang ; Fei LiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusRapid regeneration of smooth muscle after vascular injury is essential for maintaining proper artery function. The current view holds that pre-existing smooth muscle proliferate and expand in responding to vascular injury, contributing to virtually all new smooth muscle cells. Whether resident…

Medicine by Alexandros G. Sfakianakis

08:51

Quinolones in water
Multi-templates surface molecularly imprinted polymer for rapid separation and analysis of quinolones in water: AbstractRapid separation and analysis of trace quinolones (fleroxacin (FLRX), enoxacin (EN), norfloxacin (NOR), ciprofloxacin (CIP), enrofloxacin (ENRO), and lomefloxacin hydrochloride (LOME)) in real water samples were achieved by using a multi-templates molecularly imprinted polymer (MIP) based solid phase extraction (SPE) coupled with dispersive liquid-liquid microextraction (DLLME)…

Medicine by Alexandros G. Sfakianakis

08:51

Adolescents’ Views on Seeking Help for Emotional and Behavioral Problems
IJERPH, Vol. 17, Pages 191: Adolescents’ Views on Seeking Help for Emotional and Behavioral Problems: A Focus Group Study: IJERPH, Vol. 17, Pages 191: Adolescents’ Views on Seeking Help for Emotional and Behavioral Problems: A Focus Group StudyInternational Journal of Environmental Research and Public Health doi: 10.3390/ijerph17010191Authors: Suzanne J. van den Toren Amy van Grieken Marjolein Lugtenberg Mirte Boelens Hein Raat This study aimed to get insight into adolescents’ views on…

Medicine by Alexandros G. Sfakianakis

08:50

Evaluation of Retinal Nerve Fiber Layer Thickness, Electroretinogram and Visual Evoked Potential in Patients with Alzheimer’s Disease
Evaluation of Retinal Nerve Fiber Layer Thickness, Electroretinogram and Visual Evoked Potential in Patients with Alzheimer’s Disease: Objective. To study the retinal nerve fibre layer (RNFL) thickness and visual electrophysiology testing in patients with Alzheimer’s disease (AD). Methods. A cross-sectional, hospital-based study: 25 AD subjects and 25 controls were recruited. Candidates who fulfil the criteria with normal ocular examinations were made to proceed with scanning laser polarimetry, pattern…

Medicine by Alexandros G. Sfakianakis

08:49

Wooden Penetrating Pelvic Trauma Passing the Foramen Ischiadicum
Wooden Penetrating Pelvic Trauma Passing the Foramen Ischiadicum: We describe the case of a 45-year-old woman who suffered an impalement injury of the pelvis with penetration of the sciatic foramen by a wooden foreign body. Following a single operation, the injury healed without complications or infection. We have taken this as an opportunity to describe the case and our standard procedure in more detail.1. IntroductionBefore we started writing this report, we chose the terms “penetrating pelvic…

Medicine by Alexandros G. Sfakianakis

08:49

You’re Being Watched Right Now | NYT Opinion
You’re Being Watched Right Now | NYT Opinion: submitted by /u/mind_bomber [link]

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:48

Granule of BU-XIN RUAN-MAI Attenuates the Patients’ Angina Pectoris of Coronary Heart Disease via Regulating miR-542-3p/GABARAP Signaling
Granule of BU-XIN RUAN-MAI Attenuates the Patients’ Angina Pectoris of Coronary Heart Disease via Regulating miR-542-3p/GABARAP Signaling: Objective. Coronary heart disease (CHD) has been regarded as a serious and common disease in the modern society. This study aims to investigate the effect of Granule of BU-XIN RUAN-MAI (BXRM) on angina pectoris of coronary heart disease and to explore the molecular mechanisms underlying Granule of BU-XIN RUAN-MAI-mediated protective activity against this disease….

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:47

The Effect of Compound Sophora on Fluorouracil and Oxaliplatin Resistance in Colorectal Cancer Cells
The Effect of Compound Sophora on Fluorouracil and Oxaliplatin Resistance in Colorectal Cancer Cells: Fluorouracil (5-FU) and oxaliplatin (L-OHP) are the most commonly used chemotherapy drugs for colorectal cancer, though resistance is common. Compound Sophora injection is a traditional Chinese medicine that can protect the liver against oxidation, improve immunity, and enhance sensitivity to chemotherapy; it may have an effect of reversing resistance in 5-FU- and L-OHP-resistant gastric cancer cells…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:46

Quality of life is maintained with ixazomib maintenance in post‐transplant newly diagnosed multiple myeloma: the TOURMALINE‐MM3 trial
Quality of life is maintained with ixazomib maintenance in post‐transplant newly diagnosed multiple myeloma: the TOURMALINE‐MM3 trial: AbstractObjectivesHealth‐related quality of life (HRQoL) is particularly important during maintenance therapy (MT) in newly diagnosed multiple myeloma post‐transplant, when disease symptoms are limited.MethodsWe assessed HRQoL in patients randomised to 26 cycles of MT (ixazomib vs. placebo) in TOURMALINE‐MM3 (NCT02181413).ResultsCharacteristics at study entry were…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:46

Functional Brain Plasticity Associated with Anterior cruciate ligament (ACL) injury
Functional Brain Plasticity Associated with ACL Injury: A Scoping Review of Current Evidence: Anterior cruciate ligament (ACL) injury is a common problem with consequences ranging from chronic joint instability to early development of osteoarthritis. Recent studies suggest that changes in brain activity (i.e., functional neuroplasticity) may be related to ACL injury. The purpose of this article is to summarize the available evidence of functional brain plasticity after an ACL injury. A scoping review…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:46

Super-enhancer-associated oncogenes as novel therapeutic targets in osteosarcoma (ChIP-seq)
GSE134604 Super-enhancer-associated oncogenes as novel therapeutic targets in osteosarcoma (ChIP-seq): Contributors : Jiajun Zhang ; Weihai Liu ; Changye Zou ; Zhiqiang Zhao ; Yuanying Lai ; Zhi Shi ; Xianbiao Xie ; Gang Huang ; Yongqian Wang ; Xuelin Zhang ; Zeipei Fan ; Qiao Su ; Junqiang Yin ; Jingnan ShenSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensDespite the development of diagnostic and advanced treatment strategies, the…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:45

Influenza D Virus: Serological Evidence
Viruses, Vol. 12, Pages 30: Influenza D Virus: Serological Evidence in the Italian Population from 2005 to 2017: Viruses, Vol. 12, Pages 30: Influenza D Virus: Serological Evidence in the Italian Population from 2005 to 2017Viruses doi: 10.3390/v12010030Authors: Claudia M. Trombetta Serena Marchi Ilaria Manini Otfried Kistner Feng Li Pietro Piu Alessandro Manenti Fabrizio Biuso Chithra Sreenivasan Julian Druce Emanuele Montomoli Influenza D virus is a novel influenza virus,…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:45

Chimeric antigen receptor -T cell therapy: Applications and challenges in treatment of allergy and asthma
Chimeric antigen receptor -T cell therapy: Applications and challenges in treatment of allergy and asthma: Publication date: March 2020Source: Biomedicine & Pharmacotherapy, Volume 123Author(s): Abdolreza Esmaeilzadeh, Safa Tahmasebi, Seyyed Shamsadin AthariAbstractDespite the current advancements, cancer treatment approaches have limitations restricting their cure rate. Immunotherapy techniques are among novel and promising cancer therapeutic approaches. Therapeutic antibodies and adoptive cell…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:44

Cyclooxygenase activity in bradykinin-induced dermal extravasation
Cyclooxygenase activity in bradykinin-induced dermal extravasation. A study in mice and humans: ConclusionThese data suggest that COX activity contributes to bradykinin-induced dermal extravasation in mice and humans. In addition, our findings may open new treatment options and point to a potential activity of drugs interfering with the release of the COX substrate arachidonic acid, e.g. glucocorticoids.Graphical abstractGraphical illustration of the potential role of prostaglandin formation for…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:43

Lorlatinib in anaplastic lymphoma kinase-positive non-small cell lung cancer
Lorlatinib in anaplastic lymphoma kinase-positive non-small cell lung cancer: Indian experience: Vikas T Talreja, Vanita Noronha, Vijay M Patil, Amit Joshi, Kumar PrabhashSouth Asian Journal of Cancer 2020 9(1):67-68Dear Editor,Lung cancer treatment is rapidly evolving and an excellent example of precision medicine. Outcome of anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC) has improved significantly with recent report showing survival of 56% at 4 years.[1] This has been…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:42

Adequacy of surgical margins in oral cancer patients with respect to various types of reconstruction
Adequacy of surgical margins in oral cancer patients with respect to various types of reconstruction: Apurva Garg, Manish Mair, Hitesh Singhavi, Muddasir Bhati, Akshat Malik, Aseem Mishra, Deepa Nair, Sudhir Nair, Pankaj ChaturvediSouth Asian Journal of Cancer 2020 9(1):34-37Background: Surgical margin is an important prognostic factor for oral cancers (oral squamous cell carcinoma [OSCC]). The correlation of margin with the type of reconstruction has never been studied. Aim: This study aimed to…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:41

Role of Cresp® in the management of chemotherapy-induced anemia in cancer patients: A real-world clinical practice audit
Role of Cresp® in the management of chemotherapy-induced anemia in cancer patients: A real-world clinical practice audit: Ghanshyam Biswas, Avinash Pandey, Nikhil Ghadyalpatil, Nilesh Lokeshwar, Boben Thomas, Anita Ramesh, Yogesh Arora, Chandragouda Dodagoudar, Vibha Naik, Ashish Joshi, Indranil Ghosh, Rakesh Roy, Medhi Kunjahari, Tejinder Singh, Palanki Dattatreya Satya, Sachin Hingmire, Purvish M ParikhSouth Asian Journal of Cancer 2020 9(1):59-61Introduction: Anemia is a common, underestimated…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:41

Does preoperative CA-125 cutoff value and percent reduction in CA-125 levels correlate with surgical and survival outcome after neoadjuvant chemotherapy in patients with advanced-stage ovarian cancer?
Does preoperative CA-125 cutoff value and percent reduction in CA-125 levels correlate with surgical and survival outcome after neoadjuvant chemotherapy in patients with advanced-stage ovarian cancer? – Our experience from a tertiary cancer institute: Monisha Gupta, Shilpa Mukesh Patel, Ruchi Arora, Rajneesh Tiwari, Pariseema Dave, Ava Desai, Meeta MankadSouth Asian Journal of Cancer 2020 9(1):30-33Aim: The aim of the study is to evaluate percent fall in CA-125 levels after neoadjuvant chemotherapy…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:41

Epidemiology and clinical features of retinoblastoma: A tertiary care center’s experience
Epidemiology and clinical features of retinoblastoma: A tertiary care center’s experience in India: Maneya Padma, Nuthan Kumar, Prerana S Nesargi, BS Aruna Kumari, L Appaji, Aarthi ViswanathanSouth Asian Journal of Cancer 2020 9(1):56-58Introduction: Retinoblastoma (RB) is a prototype of heritable cancers. It is more common in the lower socioeconomic strata. Delayed presentation significantly reduces the overall outcome. We have analyzed the epidemiological and clinical data of children who were…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:40

Primary malignant mediastinal germ cell tumors
Primary malignant mediastinal germ cell tumors: A single institutional experience: Subhasis Mishra, Saroj Kumar Das Majumdar, Mukund Sable, Dillip Kumar ParidaSouth Asian Journal of Cancer 2020 9(1):27-29Background: Primary mediastinal malignant germ cell tumour (PMMGCT) is rare with unsatisfactory prognosis and pose difficulty in management due to lack of guidelines. Methods: All cases of PMMGCT diagnosed and treated between years 2014 to 2018 were retrospectively evaluated for clinico-pathological…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:40

The real-world experience with nivolumab in previously treated patients with advanced non-small cell lung cancer from a cancer center
The real-world experience with nivolumab in previously treated patients with advanced non-small cell lung cancer from a cancer center in India: Waseem Abbas, Rudra Prasad Acharya, Archit Pandit, Saurabh Gupta, Ranga Raju RaoSouth Asian Journal of Cancer 2020 9(1):50-52Background: PDL-1 inhibitors have emerged as the new standard of care for second line treatment of NSCLC. Methods: Eligible patients included, histologically proven NSCLC, ECOG (Eastern Cooperative Oncology Group) performance status…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:40

Using abiraterone acetate in patients of metastatic castrate-resistant prostate cancer
A tertiary care audit of using abiraterone acetate in patients of metastatic castrate-resistant prostate cancer: Amit Joshi, Sameer Shrirangwar, Vanita Noronha, Nilesh Sable, Archi Agarwal, Palak Popat, Atanu Bhattacharjee, Kumar PrabhashSouth Asian Journal of Cancer 2020 9(1):23-26Introduction: This is a retrospective analysis to assess the safety and efficacy of abiraterone acetate (AA) in metastatic castrate-resistant prostate cancer (mCRPC) patients treated at tertiary care institute. Materials…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:39

Nimotuzumab with intensity-modulated radiation therapy in unresectable and platinum-ineligible locally advanced head-and-neck cancer
Nimotuzumab with intensity-modulated radiation therapy in unresectable and platinum-ineligible locally advanced head-and-neck cancer: K Satish Srinivas, Raja Sundaram, CV Divyambika, Sameer ChaudhariSouth Asian Journal of Cancer 2020 9(1):43-46Background: Outcomes with conventional treatment are poor in patients with squamous cell carcinoma of head and neck (SCCHN). Treatment options are further limited for patients ineligible to receive platinum-based chemotherapy due to various factors such as…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:39

A rare case of hyperprogression of nonsmall cell lung cancer in a patient on atezolizumab therapy
A rare case of hyperprogression of nonsmall cell lung cancer in a patient on atezolizumab therapy: Sudarsan Vishnu Kollimuttathuillam, Supreet Kaur, Hamid Shaaban, Gunwant GuronSouth Asian Journal of Cancer 2020 9(1):22-29A 55-year-old Hispanic male with a history of hypertension presented with a 4-month history of dry cough along with mild chest pain in 2017 July when computed tomographic (CT) scan revealed right upper lobe (UL) mass with mediastinal adenopathy and innumerable pulmonary nodules….

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:39

Occupational Injury and Its Correlated Factors among Small-Scale Industry Workers
Occupational Injury and Its Correlated Factors among Small-Scale Industry Workers in Towns of Bale Zone, Southeast Ethiopia: Introduction. In developing countries, the laborer forces have managed many of the industrial works. As a result, the process of the work has put the health and lives of workers at risk. Thus, this study was designed to assess occupational injury and its correlated factors among small-scale industry workers in the towns of Bale Zone, Southeast Ethiopia. Methods. An institution-based…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:38

A prospective comparative study between concurrent chemoradiation with brachytherapy boost with concurrent chemoradiation alone in locally advanced cancer esophagus
A prospective comparative study between concurrent chemoradiation with brachytherapy boost with concurrent chemoradiation alone in locally advanced cancer esophagus: Rajanigandha TuduSouth Asian Journal of Cancer 2020 9(1):20-22Context: Carcinoma esophagus is a highly malignant disease with very low cure rate. Concurrent chemoradiation is the standard of care in patients deemed unfit for surgery. Intraluminal brachytherapy (ILRT) is effective for palliation of dysphagia and is also used as a boost…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:37

How cancer of oral cavity affects the family caregivers?
How cancer of oral cavity affects the family caregivers? – A cross-sectional study in Wardha, India, using the Caregiver Quality of Life Index – Cancer questionnaire: Sourav Goswami, Subodh Saran GuptaSouth Asian Journal of Cancer 2020 9(1):62-65Introduction: Oral cancer is now a major public health problem in India. It does not only affect the patient, but also has a deep psychosocial impact on the family caregivers who are deeply involved with the cancer patient for nursing, timely medication,…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:37

Pediatric cancers : A retrospective tertiary cancer center study
Pediatric cancers in Bihar: A retrospective tertiary cancer center study: Avinash Pandey, Anjana Singh, Vijendra Kumar, Jayant Prakash, Ritesh Runu, Vinit Thakur, Anand Kumar Gupta, Shivkant SinghSouth Asian Journal of Cancer 2020 9(1):53-55Background: There is lack of information regarding pattern of distribution of pediatric cancers in Bihar. Aim: The aim of this study is to identify the pattern of distribution of pediatric cancers. Objectives: To analyze demographic data, type, and pattern of…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:37

Reliability of conventional Papanicolaou smear in diagnosing bacterial vaginosis among women with clinical genital infection
Reliability of conventional Papanicolaou smear in diagnosing bacterial vaginosis among women with clinical genital infection: Kavita Vivek Anand, Sharmila Anil Pimple, Gauravi A Mishra, Rupali V Sahare, Saleem Pathuthara, Kedar K Deodhar, Surendra S ShastriSouth Asian Journal of Cancer 2020 9(1):13-16Objective: Bacterial vaginosis (BV) is a common reproductive tract infection (RTI) reported among Indian women. BV can influence the persistence of high-risk oncogenic human papillomavirus, a causative…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:36

Demography and treatment pattern of patients with head and neck carcinoma : Need for urgent decentralization of cancer care
Demography and treatment pattern of patients with head and neck carcinoma presenting to a tertiary care center in India: Need for urgent decentralization of cancer care: Mihir N Chandarana, Prathamesh S PaiSouth Asian Journal of Cancer 2020 9(1):38-42Aims: This study aims to report on the demographic profile and treatment pattern of head and neck cancer patients and impact of an early treatment decision on treatment. This study also aims to suggest recommendations to improve treatment compliance….

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:36

Isolated regional nodal metastasis in giant cell tumor of the bone: Case report and review of literature
Isolated regional nodal metastasis in giant cell tumor of the bone: Case report and review of literature: Kanuj Malik, Anand Raja, Sundersingh ShirleySouth Asian Journal of Cancer 2020 9(1):58-67Dear Editor,Giant cell tumors (GCTs) of the bone are benign osteolytic tumor commonly occurring in the third to fourth decades with distal femur being the most common site.[1] They form 5% of the primary skeletal tumors.[2] Metastasis though uncommon is usually seen with recurrences. Curettage with intralesional…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:35

An exceptional response to olaparib in relapsed and refractory BRCA2 mutated non-small cell lung cancer in hereditary breast–ovarian cancer syndrome
An exceptional response to olaparib in relapsed and refractory BRCA2 mutated non-small cell lung cancer in hereditary breast–ovarian cancer syndrome: Vikas T Talreja, Vanita Noronha, Amit Joshi, Vijay Patil, Kumar PrabhashSouth Asian Journal of Cancer 2020 9(1):6-12Dear Editor,Poly (ADP-ribose) polymerase inhibitors (PARPi) have demonstrated impressive efficacy in BRCA-mutated gynecological malignancies.[1],[2] Several lines of evidence now support that the DNA Damage repair (DDR)-deficient populations…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:35

Lymph node metastasis in extremity chondrosarcomas: A series of four cases
Lymph node metastasis in extremity chondrosarcomas: A series of four cases: Vineet Kurisunkal, Ashish Gulia, Ajay Puri, Bharat RekhiSouth Asian Journal of Cancer 2020 9(1):1-3Background: Primary bone sarcomas mainly metastasize through haematogenous route and rarely through lymph nodes due to paucity of lymphatic channels in the bone (1). Nodal spread in chondrosarcoma is extremely rare and there are two reported cases in literature including one previously published by our institute (3, 5). Aims…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:34

Incidence of febrile neutropenia with commonly used chemotherapy regimen in localized breast cancer
Incidence of febrile neutropenia with commonly used chemotherapy regimen in localized breast cancer: Nageswara Reddy Palukuri, Rajani Priya Yedla, Stalin Chowdary Bala, Siva Prasad Kuruva, Rachana Chennamaneni, Meher Lakshmi Konatam, Sadashivudu GundetiSouth Asian Journal of Cancer 2020 9(1):4-6Introduction: Breast cancer is the most frequently diagnosed cancer among the women. Most commonly used chemotherapy regimen is Doxorubicin and Cyclophosphamide (AC) which carries significant risk of febrile…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:34

Third-line therapy in the epidermal growth factor receptor mutation-positive advanced nonsmall-cell lung cancer
Third-line therapy in the epidermal growth factor receptor mutation-positive advanced nonsmall-cell lung cancer: Vanita Noronha, Nikhil Pande, Amit Joshi, Vijay Patil, Vaishakhi Trivedi, Anuradha Chougule, Amit Janu, Abhishek Mahajan, Vikas Talreja, Kumar PrabhashSouth Asian Journal of Cancer 2020 9(1):47-49Introduction: The treatment of lung cancer is not defined in the third-line setting and remains an unanswered question. Erlotinib is the only drug approved in the third-line setting. With the…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:34

Two duodenal gastrointestinal stroma tumors: Management by minimally invasive surgery and then by conservative surgery
Two duodenal gastrointestinal stroma tumors: Management by minimally invasive surgery and then by conservative surgery: AbstractWe report the case of a 48‐year‐old woman treated for a gastrointestinal stroma tumor of the duodenum after presenting with upper gastrointestinal bleeding. She was treated with a combination of a radiological and endoscopic approach and minimally invasive surgery. During follow‐up, the patient developed a second metachronous duodenal gastrointestinal stroma tumor, distinct…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:33

Global and mitosis‐specific interobserver variation in mitotic count scoring and implications for malignant melanoma staging
Global and mitosis‐specific interobserver variation in mitotic count scoring and implications for malignant melanoma staging: AbstractAimsStaging is the gold standard for predicting malignant melanoma outcome but changes in its criteria over time indicate ongoing evolution. One notable recent change from the 8th edition of the AJCC staging manual was removal of mitotic count. We explore the extent that this feature is limited by interobserver error in order to find ways to improve its fitness for…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:33

An Unusual Initial Presentation of Diffuse Large B-Cell Lymphoma as Recurrent Syncope
An Unusual Initial Presentation of Diffuse Large B-Cell Lymphoma as Recurrent Syncope: We describe a rare presentation of diffuse large B-cell Lymphoma (DLBCL) with recurrent episodes of syncope. During the workup for syncope, the patient was incidentally found to have an extensive mass in the left thorax, which was later diagnosed as stage 2 bulky disease DLBCL. This is the rare case of lymphoma presenting as recurrent syncope without cardiac involvement. The patient did not have any further episodes…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:33

Craniofacial Asymmetry from One to Three Years of Age: A Prospective Cohort Study with 3D Imaging
JCM, Vol. 9, Pages 70: Craniofacial Asymmetry from One to Three Years of Age: A Prospective Cohort Study with 3D Imaging: JCM, Vol. 9, Pages 70: Craniofacial Asymmetry from One to Three Years of Age: A Prospective Cohort Study with 3D ImagingJournal of Clinical Medicine doi: 10.3390/jcm9010070Authors: Anniina M. Launonen Ville Vuollo Henri Aarnivala Tuomo Heikkinen Pertti Pirttiniemi A. Marita Valkama Virpi Harila Deformational plagiocephaly (DP) is considered a risk factor for facial…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:32

Effects of a gastrin receptor antagonist (NTZ, previously named YF) on the gastric corpus mucosa of HKATPase betasubunit knockout (KO) mice
GSE142513 Effects of a gastrin receptor antagonist (NTZ, previously named YF) on the gastric corpus mucosa of HKATPase betasubunit knockout (KO) mice: Contributors : Reidar Fossmark ; Flatberg ArnarSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusPurpose: the effects of a gastrin receptor antagonist has been studies in patients with gastrin neuroendocrine (NE) tumours due to hypergastrinemia. This mouse model of hypergastrinemia is a model for studying long…

Medicine by Alexandros G. Sfakianakis

Mon Dec 23, 2019 08:59

Familial Adenomatous Polyposis and Desmoid Tumor Treated with Multivisceral Transplantation and Kidney Autotransplantation: Case Report and Literature Review
Familial Adenomatous Polyposis and Desmoid Tumor Treated with Multivisceral Transplantation and Kidney Autotransplantation: Case Report and Literature Review: Introduction. Desmoid tumours (DT) are commonly associated with Gardener’s syndrome. Their surgical resection may be complicated by their close proximity to major vessels, multiple organ involvement, and frequent local recurrence. Multivisceral transplantation (MVTx) is an alternative treatment for patients with intestinal and liver failure….

Medicine by Alexandros G. Sfakianakis

Mon Dec 23, 2019 08:58

Composition Characterization of Fatty Acid Zinc Salts by Chromatographic and NMR Spectroscopic Analyses on Their Fatty Acid Methyl Esters
Composition Characterization of Fatty Acid Zinc Salts by Chromatographic and NMR Spectroscopic Analyses on Their Fatty Acid Methyl Esters: To implement EU REACH- (Registration, Evaluation, and Authorization of Chemicals-) like chemical legislations in various countries of which the purpose is human and environment safety, the first step is substance identification followed by the hazard and risk assessments. Although both structural and composition identifications are required, the latter can more…

Medicine by Alexandros G. Sfakianakis

Mon Dec 23, 2019 08:58

Bone status of young adults with periodic avoidance of dairy products since childhood
Bone status of young adults with periodic avoidance of dairy products since childhood: AbstractProper nutrition throughout childhood and adolescence is crucial for normal bone development. We investigated whether adherence to Christian Orthodox Church fasting is characterized by periodic avoidance of animal foods (including dairy products), since childhood affects stature or bone health in young adults. This cross-sectional study included 200 healthy men and women, aged 18–35, of whom 100 had been…

Medicine by Alexandros G. Sfakianakis

Mon Dec 23, 2019 08:57

Melatonin modulates airway smooth muscle cell phenotype by targeting the STAT3/Akt/GSK-3β pathway in experimental asthma
Melatonin modulates airway smooth muscle cell phenotype by targeting the STAT3/Akt/GSK-3β pathway in experimental asthma: AbstractAmong the troika of clinicopathologic features of asthma, airway remodelling has gained sufficient attention for its contribution to progressive airway narrowing. Much effort has been directed at the management of airway smooth muscle cells (ASMCs), but few attempts have proven to prevent the progression of remodelling. Recently, accumulating data have shown the anti-inflammatory/anti-proliferative…

Medicine by Alexandros G. Sfakianakis

Mon Dec 23, 2019 08:57

Deep-learning-based Detection and Segmentation-assisted Management on Brain Metastases
Deep-learning-based Detection and Segmentation-assisted Management on Brain Metastases: AbstractBackgroundThree-dimensional T1-magnetization-prepared rapid gradient-echo (3D-T1-MPRAGE) is preferred in detecting brain metastases (BMs) among MRI. We developed an automatic deep-learning-based detection and segmentation method for BMs (named BMDS net) on 3D-T1-MPRAGE images and evaluated its performance.MethodsThe BMDS net is a cascaded 3D fully convolution network (FCN) to automatically detect and segment…

Medicine by Alexandros G. Sfakianakis

Mon Dec 23, 2019 08:57

Exposure to metal fumes and circulating miRNAs in welders
Exposure to metal fumes and circulating miRNAs in Algerian welders: AbstractPurposeA cross-sectional study was conducted in a group of Algerian welders to study the relationship between the exposure to metal particles from welding fumes and the concentration of three circulating miRNAs, miR-21, miR-146a and miR-155, as markers of renal function injury.MethodsCharacteristics of the subjects and the curriculum laboris were determined by questionnaires. We measured the concentrations of metals in blood…

Medicine by Alexandros G. Sfakianakis

Mon Dec 23, 2019 08:57

Diagnostic accuracy of transthoracic echocardiography for pulmonary hypertension
Diagnostic accuracy of transthoracic echocardiography for pulmonary hypertension: a systematic review and meta-analysis: ObjectiveTo evaluate the diagnostic accuracy of transthoracic echocardiography (TTE) in patients with pulmonary hypertension (PH).DesignSystematic review and meta-analysis.Data sources and eligibility criteriaEmbase, Cochrane Library for clinical trials, PubMed and Web of Science were used to search studies from inception to 19 June, 2019. Studies using both TTE and right heart…

Medicine by Alexandros G. Sfakianakis

Mon Dec 23, 2019 08:55

Synthesis of qualitative research studies regarding the factors surrounding UK critical care trial infrastructure
Synthesis of qualitative research studies regarding the factors surrounding UK critical care trial infrastructure: Conducting clinical trials in critical care is integral to improving patient care. Unique practical and ethical considerations exist in this patient population that make patient recruitment challenging, including narrow recruitment timeframes and obtaining patient consent often in time-critical situations. Units currently vary significantly in their ability to recruit according to infrastructure…

Medicine by Alexandros G. Sfakianakis

Mon Dec 23, 2019 08:55

Injury from electric scooters
Injury from electric scooters in Copenhagen: a retrospective cohort study: ObjectiveTo analyse injuries related to manual and electric scooter use from January 2016 up to and including July 2019.SettingElectric scooter rental services were launched in Denmark in January 2019. The services were provided by private companies. Although rules for handling and riding scooters have been established, no reports either before or after introduction of electric scooters anticipated the full extent of use,…

Medicine by Alexandros G. Sfakianakis

Mon Dec 23, 2019 08:55

Effectiveness and acceptability of cognitive-behavioural therapy based interventions for maternal peripartum depression: a systematic review, meta-analysis and thematic synthesis protocol
Effectiveness and acceptability of cognitive-behavioural therapy based interventions for maternal peripartum depression: a systematic review, meta-analysis and thematic synthesis protocol: IntroductionPeripartum depression is a common mental health difficulty associated with a range of negative impacts for the mother, infant and wider family. This review will examine the effectiveness of cognitive–behavioural therapy (CBT) based interventions for peripartum depression. Secondary aims are to explore…

Medicine by Alexandros G. Sfakianakis

Mon Dec 23, 2019 08:55

Dry cupping in the treatment of individuals with non-specific chronic low back pain: a protocol for a placebo-controlled, randomised, double-blind study
Dry cupping in the treatment of individuals with non-specific chronic low back pain: a protocol for a placebo-controlled, randomised, double-blind study: BackgroundLow back pain is a very prevalent condition in the population and cupping therapy has been presented as a frequently used non-pharmacological treatment in this population. However, there is a lack of well-designed studies that evaluate the effects of this technique. This protocol describes a placebo-controlled, randomised, double-blind…

Medicine by Alexandros G. Sfakianakis

Mon Dec 23, 2019 08:54

Real-time utilisation of administrative data in the ED to identify older patients at risk: development and validation of the Dynamic Silver Code
Real-time utilisation of administrative data in the ED to identify older patients at risk: development and validation of the Dynamic Silver Code: ObjectiveIdentification of older patients at risk, among those accessing the emergency department (ED), may support clinical decision-making. To this purpose, we developed and validated the Dynamic Silver Code (DSC), a score based on real-time linkage of administrative data.Design and settingThe ‘Silver Code National Project (SCNP)’, a non-concurrent cohort…

Medicine by Alexandros G. Sfakianakis

Mon Dec 23, 2019 08:54

Care and outcomes of children hospitalised with periorbital and orbital cellulitis: protocol for a multicentre, retrospective cohort study
Care and outcomes of Canadian children hospitalised with periorbital and orbital cellulitis: protocol for a multicentre, retrospective cohort study: IntroductionSkin and soft tissue infections of the eye can be classified based on anatomic location as either anterior to the orbital septum (ie, periorbital cellulitis) or posterior to the orbital septum (ie, orbital cellulitis). These two conditions are often considered together in hospitalised children as clinical differentiation is difficult, especially…

Medicine by Alexandros G. Sfakianakis

Mon Dec 23, 2019 08:53

Concordance of chronic conditions among the household members
Concordance of chronic conditions among the household members in Shanghai: a cross-sectional study: ObjectivesMembers living in the same household tend to share some similar behaviours and environment. We want to quantitatively assess the associations of chronic conditions to investigate the concordance of disease status among the household members.SettingShanghai, China.ParticipantsOur data were from the fifth Health Service Survey in Shanghai in 2013. 12 002 households with 31 531 residents were…

Medicine by Alexandros G. Sfakianakis

Mon Dec 23, 2019 08:53

Presidential Address: Emotion Dysregulation in Children and Adolescents
Presidential Address: Emotion Dysregulation in Children and Adolescents: I am both excited and proud to become president of our Academy of Child and Adolescent Psychiatry for the next 2 years. In addition to working with an incredible organization, I have had the privilege and pleasure of serving and collaborating with our immediate past presidents including Drs. Drell, Joshi, Fritz, and Wagner. In thinking about how I wanted to focus my energy and some of AACAP’s resources over the next couple of…

Medicine by Alexandros G. Sfakianakis

Mon Dec 23, 2019 08:52

“The Need to See and Respond”: The Role of the Child and Adolescent Psychiatrist in School Threat Assessment
“The Need to See and Respond”: The Role of the Child and Adolescent Psychiatrist in School Threat Assessment: Child and adolescent psychiatrists are on the front lines of performing challenging school threat assessments. With respect to school climate, clinicians should be aware of the presence of zero tolerance policies and inappropriate profiling. Removing a student from school does not eliminate the risk to the school community. School shootings often present similarly horrific themes and failures…

Medicine by Alexandros G. Sfakianakis

Mon Dec 23, 2019 08:52

Use of Bilateral Nasolabial Flaps with Coronoidectomy as a Novel Approach to a Case of Oral Cancer with Severe Trismus
Use of Bilateral Nasolabial Flaps with Coronoidectomy as a Novel Approach to a Case of Oral Cancer with Severe Trismus: AbstractPatients with oral malignancy often have associated trismus. Trismus is a debilitating condition that needs to be treated adequately with the release of fibrosis and interposition of vascularized tissue to provide long-term improvement in the mouth opening. Treatment of oral cancer in patients with severe trismus becomes challenging because of difficult access and further…

Medicine by Alexandros G. Sfakianakis

Mon Dec 23, 2019 08:51

Distal Femoral Varus Osteotomy for the Valgus Knee after Distal Femoral Growth Plate Fractures in Children: A Case Report
Distal Femoral Varus Osteotomy for the Valgus Knee after Distal Femoral Growth Plate Fractures in Children: A Case Report: An 18-year-old male suffered a valgus injury to the right knee due to a fall during a bigfoot race he took part in when he was 15 years old. He visited a different hospital at the age of 15. No obvious ligament injury or fracture was noted on MRI and physical examination. However, he gradually became aware of the valgus deformity of the right knee. Finally, he could not take…

Medicine by Alexandros G. Sfakianakis

Mon Dec 23, 2019 08:51

Identification of a truncated {beta}1-chimaerin variant that inactivates nuclear Rac1 [Signal Transduction]
Identification of a truncated {beta}1-chimaerin variant that inactivates nuclear Rac1 [Signal Transduction]: β1-chimaerin belongs to the chimaerin family of GTPase-activating proteins (GAPs) and is encoded by the CHN2 gene that also encodes the β2- and β3-chimaerin isoforms. All chimaerin isoforms have a C1 domain that binds diacylglycerol (DAG), as well as the tumor-promoting phorbol esters, and a catalytic GAP domain that inactivates the small GTPase Rac. Nuclear Rac has emerged as a key regulator…

Medicine by Alexandros G. Sfakianakis

Mon Dec 23, 2019 08:50

A fluorescent nanosphere-based immunochromatography test strip for ultrasensitive and point-of-care detection of tetanus antibody in human serum
A fluorescent nanosphere-based immunochromatography test strip for ultrasensitive and point-of-care detection of tetanus antibody in human serum: AbstractTetanus still possesses a high infection risk and leads a number of human deaths in poor nations. Point-of-care and ultrasensitive detection of tetanus antibody levels in serum is the key to decrease the risk of tetanus infection and improve the health of people. In this work, by using ultra bright fluorescent nanospheres (FNs) and portable lateral…

Medicine by Alexandros G. Sfakianakis

Mon Dec 23, 2019 08:50

Cancer Stem Cells Equipped with Powerful Hedgehog Signaling and Better Epigenetic Memory: Avenues to Look for Cancer Therapeutics
Cancer Stem Cells Equipped with Powerful Hedgehog Signaling and Better Epigenetic Memory: Avenues to Look for Cancer Therapeutics: Complex nature of the tumor is depicted at the cellular landscape by showing heterogeneity in the presence of cancer cells, cancer-associated stromal cells, mesenchymal stem cells and cancer stem cells (CSCs). One of the plausible views in cancer formation is suggested as the theory of cancer CSCs that is known as a source of initiation of tumorigenesis. In essence, these…

Medicine by Alexandros G. Sfakianakis

Mon Dec 23, 2019 08:49

Advances in In-Silico based Predictive In-Vivo Profiling of Novel Potent β-Glucuronidase Inhibitors
Advances in In-Silico based Predictive In-Vivo Profiling of Novel Potent β-Glucuronidase Inhibitors: Background: Intestinal β-glucuronidase enzyme has a significant importance in colorectal carcinogenesis. Specific inhibition of the enzyme helps prevent immune reactivation of the glucuronide- carcinogens, thus protecting the intestine from ROS (Reactive Oxidative Species) mediatedcarcinogenesis. Objectives: Advancement in In-silico based techniques has provided a broad range of studies to carry out…

Medicine by Alexandros G. Sfakianakis

Mon Dec 23, 2019 08:49

Mogroside V Inhibits Hyperglycemia-induced Lung Cancer Cells Metastasis through Reversing EMT and Damaging Cytoskeleton
Mogroside V Inhibits Hyperglycemia-induced Lung Cancer Cells Metastasis through Reversing EMT and Damaging Cytoskeleton: Background: Diabetes Mellitus (DM) accelerates progress of lung cancer. Hyperglycemia, a critical feature of DM, promotes lung cancer metastasis. Mogroside V is a triterpenoid glycoside from Siraitia grosvenorii. Interestingly, mogroside V not only plays an anti-diabetic role, but also has anti-tumor effects. Objective: In this study, we investigated the metastatic efficiency of…

Medicine by Alexandros G. Sfakianakis

Mon Dec 23, 2019 08:49

The Role of Large Neutral Amino Acid Transporter (LAT1) in Cancer
The Role of Large Neutral Amino Acid Transporter (LAT1) in Cancer: Background: The solute carrier family 7 (SLC7) can be categorically divided into two subfamilies, the L-type amino acid transporters (LATs) including SLC7A5-13, and SLC7A15, and the cationic amino acid transporters (CATs) including SLC7A1-4 and SLC7A14. Members of the CAT family transport predominantly cationic amino acids by facilitating diffusion with intracellular substrates. LAT1 (also known as SLC7A5), is defined as a heteromeric…

Medicine by Alexandros G. Sfakianakis

Mon Dec 23, 2019 08:49

Study of Serum Soluble Programmed Death Ligand 1 as a Prognostic Factor in Hepatocellular Carcinoma
Study of Serum Soluble Programmed Death Ligand 1 as a Prognostic Factor in Hepatocellular Carcinoma in Egyptian Patients: Background: The expression of programmed cell death ligands on tumor cells has a role in the suppression of antitumor immunity, resulting in tumor immune evasion. Objective: In this study, we evaluated the prognostic value of the soluble form of programmed death-ligand1 (sPD-L1) in Egyptian hepatocellular carcinoma (HCC) patients. Methods: This prospective cohort study was performed…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

Mon Dec 23, 2019 08:48

The Role of Shcbp1 in Signaling and Disease
The Role of Shcbp1 in Signaling and Disease: Src homolog and collagen homolog (Shc) proteins have been identified as adapter proteins associated with cell surface receptors and have been shown to play important roles in signaling and disease. Shcbp1 acts as a Shc SH2-domain binding protein 1 and is involved in the regulation of signaling pathways, such as FGF, NF-κB, MAPK/ERK, PI3K/AKT, TGF-β1/Smad and β -catenin signaling. Shcbp1 participates in T cell development, the regulation of downstream signal…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

Mon Dec 23, 2019 08:48

Differential Expression of TOM34, AL1A1, PADI2 and KLRBA in NNK Induced Lung Cancer in Wistar Rats and their Implications
Differential Expression of TOM34, AL1A1, PADI2 and KLRBA in NNK Induced Lung Cancer in Wistar Rats and their Implications: Background: Lung cancer is the most common cancer with a high mortality rate. The diagnosis only at advanced stages and lack of effective treatment are the main factors responsible for high mortality. Tobacco smoke is the major responsible factor for inflammation and tumor development in lungs. Objective: The present study was carried out to identify differentially expressed…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

Mon Dec 23, 2019 08:48

Long-Term, Real-World Safety and Efficacy of Teneligliptin
Long-Term, Real-World Safety and Efficacy of Teneligliptin: A Post-Marketing Surveillance of More Than 10,000 Patients with Type 2 Diabetes in Japan: AbstractIntroductionTeneligliptin is a dipeptidyl peptidase 4 inhibitor that was approved for the treatment of type 2 diabetes mellitus (T2DM) in Japan in 2012. We performed a long-term post-marketing surveillance (RUBY) to obtain real-world evidence regarding the safety and efficacy of teneligliptin in Japan.MethodsThis 3-year follow-up RUBY surveillance…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

Mon Dec 23, 2019 08:47

Employment Experiences among Young Adults with Learning Disabilities
IJERPH, Vol. 17, Pages 115: Employment Experiences among Young Malaysian Adults with Learning Disabilities: IJERPH, Vol. 17, Pages 115: Employment Experiences among Young Malaysian Adults with Learning DisabilitiesInternational Journal of Environmental Research and Public Health doi: 10.3390/ijerph17010115Authors: Dzalani Harun Normah Che’ Din Hanif Farhan Mohd Rasdi Khadijah Shamsuddin The aim of this study was to describe the employment experiences of persons with learning disabilities…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

Mon Dec 23, 2019 08:47

Synthesis of mesoporous magnetic polypyrrole and its application in studies of removal of acidic, neutral, and basic pharmaceuticals from aqueous medium
Synthesis of mesoporous magnetic polypyrrole and its application in studies of removal of acidic, neutral, and basic pharmaceuticals from aqueous medium: AbstractAs an alternative to traditional adsorbents, mesoporous magnetic polypyrrole (MMPPy) was first used as an adsorbent for the removal of acid, neutral, and basic pharmaceutical compounds considered aqueous pollutants. Ibuprofen (IBU, acid), caffeine (CAF, neutral), and bupropion (BUP, basic) were chosen as adsorbates and applied in adsorption…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

Mon Dec 23, 2019 08:46

Association of the primary tumor’s SUVmax with survival after surgery for clinical stage IA esophageal cancer: a single-center retrospective study
Association of the primary tumor’s SUVmax with survival after surgery for clinical stage IA esophageal cancer: a single-center retrospective study: AbstractBackgroundCompared to other esophageal cancers, clinical stage IA esophageal cancer generally has a good prognosis, although a subgroup of patients has a poor prognosis. Unfortunately, clinical diagnoses of invasion depth or lymph node metastasis are not always accurate, which make it difficult to identify patients with a high risk of postoperative…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

Mon Dec 23, 2019 08:45

Hypertension in HIV-Infected Patients Receiving Antiretroviral Therapy
Hypertension in HIV-Infected Patients Receiving Antiretroviral Therapy in Northeast Ethiopia: Background. With prolonged survival and aging of persons with HIV on combination antiretroviral therapy (ART), hypertension has emerged as a significant cause of morbidity and mortality globally. However, little is known about the burden of this comorbid condition among adults living with HIV in sub-Saharan Africa. In this study, we aimed to determine the prevalence and factors associated with hypertension…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

Mon Dec 23, 2019 08:45

Novel Urinary Biomarkers for Acute Kidney Injury and Prediction of Clinical Outcomes After Pediatric Cardiac Surgery
Novel Urinary Biomarkers for Acute Kidney Injury and Prediction of Clinical Outcomes After Pediatric Cardiac Surgery: AbstractAcute kidney injury (AKI) is a serious complication of pediatric cardiac surgery, with high morbidity and mortality. We aimed to evaluate the perioperative risk factors for AKI, and the validity of novel diagnostic urinary biomarkers after pediatric cardiac surgery. We analyzed 103 consecutive pediatric patients (≤ 18 years old), who underwent cardiac surgery. AKI was defined…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

Mon Dec 23, 2019 08:45

Antibiotic-Associated Diarrhea
Antibiotics, Vol. 9, Pages 8: The Structure Features and Improving Effects of Polysaccharide from Astragalus membranaceus on Antibiotic-Associated Diarrhea: Antibiotics, Vol. 9, Pages 8: The Structure Features and Improving Effects of Polysaccharide from Astragalus membranaceus on Antibiotic-Associated DiarrheaAntibiotics doi: 10.3390/antibiotics9010008Authors: Shanshan Li Yuli Qi Duoduo Ren Di Qu Yinshi Sun Astragalus membranaceus (Astragalus) is often used as a medical and food resource…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

Mon Dec 23, 2019 08:45

Risk factors associated with delayed methotrexate clearance and increased toxicity in pediatric patients with osteosarcoma
Risk factors associated with delayed methotrexate clearance and increased toxicity in pediatric patients with osteosarcomaby Elizabeth P. Young, W. Susan Cheng, Melanie B. Bernhardt, Lisa L. Wang, Nino Rainusso, Jennifer H. Foster via Pediatric Blood & CancerAbstractHigh‐dose methotrexate (HD‐MTX; 12 g/m2) is part of standard therapy for pediatric osteosarcoma (OS). Risk factors associated with MTX toxicity in children with OS are not well defined. We investigated the association between peak…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

Mon Dec 23, 2019 08:44

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com, Telephone consultation 11855 int 1193,

Pathology-confirmed versus non pathology-confirmed cancer diagnoses: incidence, participant characteristics, and survival
Pathology-confirmed versus non pathology-confirmed cancer diagnoses: incidence, participant characteristics, and survival: AbstractCancer diagnoses which are not confirmed by pathology are often under-registered in cancer registries compared to pathology-confirmed diagnoses. It is unknown how many patients have a non pathology-confirmed cancer diagnosis, and whether their characteristics and survival differ from patients with a pathology-confirmed diagnosis. Participants from the prospective population-based…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:19

Evaluation of CCR5‐Δ32 Mutation among Individuals with High Risk Behaviours, Neonates Born to HIV‐1 Infected Mothers, HIV‐1 Infected Individuals, and Healthy People in an Iranian Population
Evaluation of CCR5‐Δ32 Mutation among Individuals with High Risk Behaviours, Neonates Born to HIV‐1 Infected Mothers, HIV‐1 Infected Individuals, and Healthy People in an Iranian Population: AbstractOne of the important genetic factors related to resistance to HIV‐1 infection is the presence of the C‐C chemokine receptor type 5 delta 32 (CCR5‐Δ32) homozygous genotype (Δ32/Δ32). The aim of this study was to evaluate the CCR5‐Δ32 mutation among individuals with high‐risk behaviours, neonates born to…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:18

Placental Infection of Hepatitis B Virus among Thai Pregnant Women: Clinical Risk Factors and Its Association with Fetal infection
Placental Infection of Hepatitis B Virus among Thai Pregnant Women: Clinical Risk Factors and Its Association with Fetal infection: AbstractObjectivesTo identify the risk factors of placental and fetal infections among HBsAg‐positive women.MethodsA prospective cohort study involving HBsAg‐positive pregnant women was conducted. Maternal risk factors, including serum HBeAg status, anti‐HBcIgM, and HBV‐DNA levels were determined. Placental infection was identified by PCR and confirmed by DNA sequencing….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:18

Towards simple tools to assess functional effects of contaminants on natural microbial and invertebrate sediment communities
Towards simple tools to assess functional effects of contaminants on natural microbial and invertebrate sediment communities: AbstractSurface sediments can accumulate contaminants that affect microorganisms and invertebrates and disturb benthic ecological functions. However, effects of contaminants on ecological functions supported by sediment communities are understudied. Here, we tested the relevance of two simple tools to assess the ecotoxicological effects of metal contamination on natural sediment…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:18

Comparative evaluation of four suspended particulate matter (SPM) sampling devices and their use for monitoring SPM quality
Comparative evaluation of four suspended particulate matter (SPM) sampling devices and their use for monitoring SPM quality: AbstractRepresentative sampling of suspended particulate matter is fundamental for assessing river sediment quality, including the distribution and physicochemical characterisation of particles at different hydrological events. This study compares time-integrated samplers and discrete sampling methods, focusing on (a) the representativeness of the different methods and (b)…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:18

Impaired intrinsic functional connectivity between the thalamus and visual cortex in migraine without aura
Impaired intrinsic functional connectivity between the thalamus and visual cortex in migraine without aura: Resting-state functional magnetic resonance imaging (fMRI) has confirmed disrupted visual network connectivity in migraine without aura (MwoA). The thalamus plays a pivotal role in a number of pain conditions,… Research articleOpen AccessPublished: 19 December 2019Impaired intrinsic functional connectivity between the thalamus and visual cortex in migraine without auraHeng-Le Wei, Xin Zhou,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:18

Soluble levels of sCD40L and s4‐1BB are associated with a poor prognosis in elderly patients with colorectal cancer
Soluble levels of sCD40L and s4‐1BB are associated with a poor prognosis in elderly patients with colorectal cancer: AbstractBackground and ObjectivesThe prognosis of colorectal cancer (CRC) has improved in the last decades, however, a lower overall survival persists in the elderly. The understanding of immunity changes in the elderly with CRC will allow the emergence of new treatments with higher response rates. 4‐1BB and CD40L, an immune checkpoint stimulator, play an important role in T‐cell responses…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:16

Clinical presentation and surgical outcomes in primary aldosteronism differ by race
Clinical presentation and surgical outcomes in primary aldosteronism differ by race: AbstractBackgroundPrimary aldosteronism (PA) is the most common cause of secondary hypertension; early diagnosis and intervention correlate with outcomes. We hypothesized that race may influence clinical presentation and outcomes.MethodsWe conducted a retrospective analysis of patients with PA (1997‐2017) who underwent adrenal vein sampling (AVS). Patients were classified by self‐reported race as black or non‐black….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:12

Towards a standard pathological and molecular characterization of recurrent glioma in adults: a RANO effort
Towards a standard pathological and molecular characterization of recurrent glioma in adults: a RANO effort: AbstractRegardless of subtype, diffuse gliomas of adulthood are characterized by inexorable progression through treatment. Cancer recurrence in the context of therapy is by no means unique to gliomas. For many tumors residing outside the central nervous system (CNS), tissue-based analyses are routinely employed to document the molecular and cellular features of disease recurrence. Such interventions…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:11

Evaluation of Store Environment Changes of an In-Store Intervention to Promote Fruits and Vegetables
IJERPH, Vol. 17, Pages 65: Evaluation of Store Environment Changes of an In-Store Intervention to Promote Fruits and Vegetables in Latino/Hispanic-Focused Food Stores: IJERPH, Vol. 17, Pages 65: Evaluation of Store Environment Changes of an In-Store Intervention to Promote Fruits and Vegetables in Latino/Hispanic-Focused Food StoresInternational Journal of Environmental Research and Public Health doi: 10.3390/ijerph17010065Authors: Jennifer Sanchez-Flack Barbara Baquero Shih-Fan Lin George…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:11

Emergencies in Long-Term Care Services for the Elderly
IJERPH, Vol. 17, Pages 66: Emergencies in Long-Term Care Services for the Elderly in Korea: A Mixed-Methods Study: IJERPH, Vol. 17, Pages 66: Emergencies in Long-Term Care Services for the Elderly in Korea: A Mixed-Methods StudyInternational Journal of Environmental Research and Public Health doi: 10.3390/ijerph17010066Authors: Soon Ok Kim Sun Hee Bae This mixed-methods study explored ways to enhance the emergency response abilities of workers in long-term care services for the elderly. Based…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:11

Changes in heparan sulfate sulfotransferases and cell-surface heparan sulfate during SKM-1 cells granulocytic differentiation and A549 cells epithelial-mesenchymal transition
Changes in heparan sulfate sulfotransferases and cell-surface heparan sulfate during SKM-1 cells granulocytic differentiation and A549 cells epithelial-mesenchymal transition: AbstractHeparan sulfate (HS) with various sulfation patterns is one of important modulators of cancer cell fate through interacting with numerous growth factors. Here we found HS 2-O sulfotransferase 1 (HS2ST1) was downregulated at both mRNA and protein levels during granulocytic differentiation of SKM-1 leukemia cells and…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:11

Perception of quality of intraoperative fluoroscopy and the influence on postoperative management: an international survey
Perception of quality of intraoperative fluoroscopy and the influence on postoperative management: an international survey: AbstractPurposeIntraoperative precise visualization of fractures and assessment of the quality of reduction is essential in orthopedic trauma surgery. Fluoroscopic skills will lead to an increased detection rate of minimal abnormalities needing revision intraoperatively. The definition of fluoroscopic skills and the interpretation of acceptable “minimal abnormalities” remains…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:10

Curcumin-In-Deformable Liposomes-In-Chitosan-Hydrogel as a Novel Wound Dressing
Pharmaceutics, Vol. 12, Pages 8: Curcumin-In-Deformable Liposomes-In-Chitosan-Hydrogel as a Novel Wound Dressing: Pharmaceutics, Vol. 12, Pages 8: Curcumin-In-Deformable Liposomes-In-Chitosan-Hydrogel as a Novel Wound DressingPharmaceutics doi: 10.3390/pharmaceutics12010008Authors: Selenia Ternullo Laura Victoria Schulte Werning Ann Mari Holsæter Nataša Škalko-Basnet A liposomes-in-hydrogel system as an advanced wound dressing for dermal delivery of curcumin was proposed for improved chronic…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:09

The Potential Role of Cycloastragenol in Promoting Diabetic Wound Repair In Vitro
The Potential Role of Cycloastragenol in Promoting Diabetic Wound Repair In Vitro: Background. Refractory wound healing is a severe complication of diabetes with a significant socioeconomic burden. Whereas current therapies are insufficient to accelerate repair, stem cell-based therapy is increasingly recognized as an alternative that improves healing outcomes. The aim of the present study is to explore the role of cycloastragenol (CAG), a naturally occurring compound in Astragali Radix, in ameliorating…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:09

Inhibition of HMGB1 Promotes Osseointegration under Hyperglycemic Condition through Improvement of BMSC Dysfunction
Inhibition of HMGB1 Promotes Osseointegration under Hyperglycemic Condition through Improvement of BMSC Dysfunction: High mobility group box 1 (HMGB1) participates actively in oxidative stress damage and the latter relates closely to diabetic complications, including poor implant osseointegration. This article is aimed at investigating the effects of HMGB1 on dysfunction of bone marrow stromal cells (BMSCs) and impaired osseointegration under diabetic environment. In vitro, BMSCs were treated with…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:09

THAP11F80L cobalamin disorder-associated mutation reveals normal and pathogenic THAP11 functions in gene expression and cell proliferation"
GSE138205 ChIP-seq experiments for "THAP11F80L cobalamin disorder-associated mutation reveals normal and pathogenic THAP11 functions in gene expression and cell proliferation": Contributors : Maykel Lopes ; Philippe L’Hôte ; Hamonie Dehaene ; Viviane Praz ; Winship HerrSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensTwelve human THAP proteins share the THAP domain, an evolutionary conserved zinc-finger DNA-binding domain. Studies of different…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:08

Cancer-Associated Fibroblasts in Undifferentiated Nasopharyngeal Carcinoma
Pathogens, Vol. 9, Pages 8: Cancer-Associated Fibroblasts in Undifferentiated Nasopharyngeal Carcinoma: A Putative Role for the EBV-Encoded Oncoprotein, LMP1: Pathogens, Vol. 9, Pages 8: Cancer-Associated Fibroblasts in Undifferentiated Nasopharyngeal Carcinoma: A Putative Role for the EBV-Encoded Oncoprotein, LMP1Pathogens doi: 10.3390/pathogens9010008Authors: Mhairi A. Morris Undifferentiated nasopharyngeal carcinoma (NPC) is 100% associated with Epstein–Barr virus (EBV) infection, and biopsies…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:08

Prenatal Diagnosis of Umbilical Cord Ulcer
Prenatal Diagnosis of Umbilical Cord Ulcer: A Report of Two Cases: Umbilical cord ulcer is related to fetal intestinal atresia or meconium; perforation of the ulcer causes fetal deterioration leading to fetal and neonatal death owing to fetal hemorrhage. However, to the best of our knowledge, a method to diagnose umbilical cord ulcer prenatally is not available. No reports exist about the prenatal findings before perforation of umbilical cord ulcer using ultrasonography. We encountered two cases…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:07

Anaerobic Bacteremias in Left Ventricular Assist Devices and Advanced Heart Failure
Anaerobic Bacteremias in Left Ventricular Assist Devices and Advanced Heart Failure: Left ventricular assisted devices (LVADs) have revolutionized the treatment of advanced heart failure, providing meaningful increases in survival, functional capacity, and quality of life. There are two categories of LVADs patients: (1) bridge-to-transplant and (2) destination therapy. Advanced heart failure and destination LVADs often carry a poor prognosis. The overall 1-year mortality rate remains as high as 30%….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:07

Continuous intravenous low-dose diclofenac sodium to control a central fever after ischemic stroke in the intensive care unit: a case report and review of the literature
Continuous intravenous low-dose diclofenac sodium to control a central fever after ischemic stroke in the intensive care unit: a case report and review of the literature: Elevation in body temperature within the first 24 hours of ischemic stroke is fairly common and known to be associated with worse outcomes. Only after thoroughly ruling out infection and the noninfectious etio… Case reportOpen AccessOpen Peer ReviewPublished: 18 December 2019Continuous intravenous low-dose diclofenac sodium to…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:06

Neck paraganglioma and follicular lymphoma: a case report
Neck paraganglioma and follicular lymphoma: a case report: AbstractBackgroundParagangliomas and pheochromocytomas are sympathetic or parasympathetic tumors derived from the paraganglia and the adrenal medulla, respectively. Paragangliomas and pheochromocytomas can be sporadic or familial, the latter frequently being multifocal and possibly due to succinate dehydrogenase complex genes mutations. In addition, 12% of sporadic paragangliomas are related to covered succinate dehydrogenase complex mutations….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:05

Chemotherapy-associated neutropenic enterocolitis of the transverse colon post right hemicolectomy
Chemotherapy-associated neutropenic enterocolitis of the transverse colon post right hemicolectomy: AbstractNeutropenic enterocolitis (NE) is a life-threatening infection of the immunocompromised. NE ubiquitously affects the cecum, often with involvement of the ascending colon and ileum. Classically, NE is associated with high mortality leading to the frequent use of aggressive treatment strategies including surgery. Although conservative approaches are often successful, there are currently no standardized…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:05

Development of multiple adrenal myelolipomas after trauma-induced adrenal haemorrhage
Development of multiple adrenal myelolipomas after trauma-induced adrenal haemorrhage: Adrenal myelolipomas represent a benign neoplasm with known associations with many chronic diseases, 21-hydroxylase deficiency and cancer. However, the aetiology of adrenal myelolipomas remains unknown. Here, we present a case of a patient with image-proven bilateral adrenal haemorrhages caused by trauma with the subsequent development of bilateral adrenal myelolipomas several years later. Resection and pathological…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:04

Lupus cystitis: unusual cause of renal failure in systemic lupus erythematosus
Lupus cystitis: unusual cause of renal failure in systemic lupus erythematosus: A 42-year-old woman presented with chronic fever, abdominal pain, intermittent loose stools and dysuria for 3 months. She had recently developed acute dyspnoea with acute kidney injury. She was found to have a contracted, thick-walled bladder with bilateral hydroureteronephrosis. She underwent bilateral percutaneous nephrostomies, following which her renal function recovered. She satisfied the clinical and immunological…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:04

Organising pneumonia in Rhupus syndrome.Rhupus syndrome is a rare combination of rheumatoid arthritis and systemic lupus erythematosus, and is characterized by the presence of erosive arthritis together with symptoms and signs of systemic lupus erythematosus.
Organising pneumonia in Rhupus syndrome: Interstitial lung disease (ILD) is seen in 17% of patients with Rhupus syndrome. Organising pneumonia (OP), a subtype of connective tissue disease-associated ILD, is rare but associated with good outcomes. Here, we present a patient with Rhupus who developed OP.

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:04

Native valve endocarditis caused by ErysipelothrixRhusiopathiae: presenting with refractory heart failure and requiring surgical valve replacement–report on a rare zoonosis
Native valve endocarditis caused by ErysipelothrixRhusiopathiae: presenting with refractory heart failure and requiring surgical valve replacement–report on a rare zoonosis: Erysipelothrix Rhusiopathiae is a Gram-positive bacillus that is ubiquitous in nature. The bacterium is a zoonotic pathogen known to infect wild and domestic animals. Human infections, however, are uncommon and typically present with localised or generalised cutaneous lesions. Systemic infection in the form of bacteraemia with…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:03

Is dapsone still relevant in immune thrombocytopenia in resource limited settings?
Is dapsone still relevant in immune thrombocytopenia in resource limited settings?: Immune thrombocytopenia is an autoimmune disorder characterised by autoantibody production against platelets, increased platelet destruction and impaired thrombopoiesis. Steroids are the first-line agents whenever treatment is indicated; however, some patients may not respond and the responders may as well relapse while the dose is being tapered. Side effects of steroids prohibits their long-term use and patients…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:03

Sertraline-induced hypersensitivity pneumonitis
Sertraline-induced hypersensitivity pneumonitis: Hypersensitivity pneumonitis (HP), also known as extrinsic allergic alveolitis, is a granulomatous, non-IgE-mediated hypersensitivity reaction of the alveoli and distal bronchioles presenting as an acute, subacute or chronic condition. It is most commonly associated with exposure to extrinsic allergens (eg, avian dust, mould and tobacco) and medications including antiarrhythmics (eg, amiodarone), cytotoxics (eg, methotrexate) and antiepileptics (eg,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:03

Five-Year Recall after Treatment of External Cervical Resorption
Five-Year Recall after Treatment of External Cervical Resorption: The management of external cervical resorption can be challenging. This study described a two-step procedure for the treatment of external cervical resorption. It involved nonsurgical root canal treatment and a dental amalgam core buildup, followed by a surgical approach to restore the root structure using resin-modified glass ionomer (Geristore®). The patient was recalled for a period of five years, and the overall outcome was successful.

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:03

A new deep learning method for image deblurring in optical microscopic systems
A new deep learning method for image deblurring in optical microscopic systems: Deconvolution is the most commonly used image processing method in optical imaging systems to remove the blur caused by the point‐spread‐function (PSF). While this method has been successful in deblurring, it suffers from several disadvantages, such as slow processing time due to multiple iterations required to deblur and suboptimal in cases where the experimental operator chosen to represent PSF is not optimal. In this…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:02

Risk of spread in adult-onset isolated focal dystonia: a prospective international cohort study.
Risk of spread in adult-onset isolated focal dystonia: a prospective international cohort study.: Related ArticlesRisk of spread in adult-onset isolated focal dystonia: a prospective international cohort study.J Neurol Neurosurg Psychiatry. 2019 Dec 17;:Authors: Berman BD, Groth CL, Sillau SH, Pirio Richardson S, Norris SA, Junker J, Brüggemann N, Agarwal P, Barbano RL, Espay AJ, Vizcarra JA, Klein C, Bäumer T, Loens S, Reich SG, Vidailhet M, Bonnet C, Rose E, Jinnah HA, Perlmutter JSAbstract …

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:02

Mutation signature analysis identifies increased mutation caused by tobacco smoke associated DNA adducts in larynx squamous cell carcinoma compared with oral cavity and oropharynx.
Mutation signature analysis identifies increased mutation caused by tobacco smoke associated DNA adducts in larynx squamous cell carcinoma compared with oral cavity and oropharynx.: Related ArticlesMutation signature analysis identifies increased mutation caused by tobacco smoke associated DNA adducts in larynx squamous cell carcinoma compared with oral cavity and oropharynx.Sci Rep. 2019 Dec 17;9(1):19256Authors: South AP, den Breems NY, Richa T, Nwagu U, Zhan T, Poojan S, Martinez-Outschoorn U,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:02

Many-isocenter optimization for robotic radiotherapy.
Many-isocenter optimization for robotic radiotherapy.: Related ArticlesMany-isocenter optimization for robotic radiotherapy.Phys Med Biol. 2019 Dec 18;:Authors: Lyu Q, Neph R, Yu VY, Ruan D, Boucher S, Sheng KAbstract Despite significant dosimetric gains, clinical implementation of the 4π non-coplanar radiotherapy on the widely available C-arm gantry system is hindered by limited clearance, and the need to perform complex coordinated gantry and couch motion. A robotic radiotherapy platform…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:02

Narrow Band Imaging for lingual tonsil hypertrophy and inflammation, in laryngo-pharyngeal reflux disease
Narrow Band Imaging for lingual tonsil hypertrophy and inflammation, in laryngo-pharyngeal reflux disease: AbstractPurposeThe objective of this study is to analyse the relationship between the endoscopic signs of laryngo-pharyngeal reflux, the lingual tonsil hypertrophy (LTH) and its inflammation, adopting Narrow Band Imaging (NBI) technology.MethodsWe enrolled, as cases, patients with clinical diagnosis of laryngopharyngeal reflux disease (LPRD), a Reflux Symptom Index (RSI) ≥ 13, and a Reflux Finding…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:02

The effect of canal diameter on audiologic results in patients with cochlear implantation with large vestibular aqueduct syndrome.
The effect of canal diameter on audiologic results in patients with cochlear implantation with large vestibular aqueduct syndrome.: Related ArticlesThe effect of canal diameter on audiologic results in patients with cochlear implantation with large vestibular aqueduct syndrome.Eur Arch Otorhinolaryngol. 2019 Dec 17;:Authors: Demir B, Cesur S, Incaz S, Alberalar ND, Ciprut A, Batman CAbstract PURPOSE: To compare audiologic results according to vestibular aqueduct (VA) diameter in patients…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:01

The effect of anatomic variations and maxillary sinus volume in antrochoanal polyp formation.
The effect of anatomic variations and maxillary sinus volume in antrochoanal polyp formation.: Related ArticlesThe effect of anatomic variations and maxillary sinus volume in antrochoanal polyp formation.Eur Arch Otorhinolaryngol. 2019 Dec 17;:Authors: Başer E, Sarıoğlu O, Arslan İB, Çukurova İAbstract PURPOSE: The antrochoanal polyp (ACP), otherwise known as the Killain polyp, is a benign lesion that originates from maxillary sinus mucosa, extending from the accessory ostium towards the…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:01

Panel 2- Recent Advance in Otitis Media Bioinformatics
Panel 2- Recent Advance in Otitis Media Bioinformatics: Publication date: Available online 18 December 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Ann Hermansson, Diego Preciado, Jian-Dong Li, Kensei Komatsu, Arwa Kurabi, Gustavo Nino, Stephanie Val, Shyan Vijayasekaran, Oren ZivAbstractObjectivesTo update the medical literature on recent large-scale studies employing bioinformatics data analysis tools in otitis media (OM) disease models with a principal focus on…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:00

The natural history of the otitis media microbiome and its response to environmental pressures
Recent advances in understanding the natural history of the otitis media microbiome and its response to environmental pressures: Publication date: Available online 18 December 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Robyn L. Marsh, Celestine Aho, Jemima Beissbarth, Seweryn Bialasiewicz, Michael Binks, Anders Cervin, Lea-Ann S. Kirkham, Katherine P. Lemon, Mary PE. Slack, Heidi C. Smith-VaughanAbstractObjectiveTo perform a comprehensive review of otitis media microbiome…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:00

Panel 8: Vaccines and Immunology
Panel 8: Vaccines and Immunology: Publication date: Available online 18 December 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Mark R. Alderson, Tim Murphy, Stephen I. Pelton, Laura A. Novotny, Laura L. Hammitt, Arwa Kurabi, Jian-Dong Li, Ruth B. Thornton, Lea-Ann S. KirkhamAbstractObjectiveTo review and highlight significant advances made towards vaccine development and understanding of the immunology of otitis media (OM) since the 19th International Symposium on Recent…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:00

Trajectory of change in the swallowing status in spinal muscular atrophy type I
Trajectory of change in the swallowing status in spinal muscular atrophy type I: Publication date: Available online 18 December 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Young-Ah Choi, Dong-In Suh, Jong-Hee Chae, Hyung-Ik ShinAbstractObjectivesThis study aimed to elucidate the change in progressive swallowing dysfunction from birth up to 2 years of age to provide clinical insights into the management of swallowing difficulty in patients with spinal muscular atrophy…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:00

Intracranial complications of pediatric rhinosinusitis: The most common presenting symptoms were fever and headache. Localizing neurological symptoms including hemiparesis and aphasia, in addition to seizures occurred in 33% of patients and increased LOH significantly (33 versus 15 days, p = 0.03). Epidural (EA) and subdural abscesses (SA) were the most common intracranial complications.
Intracranial complications of pediatric rhinosinusitis: identifying risk factors and interventions affecting length of hospitalization: Publication date: Available online 19 December 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Corina Din-Lovinescu, Ghayoour Mir, Conor Blanco, Kevin Zhao, Thomas Mazzoni, Arno Fried, Mostafa El Khashab, Giant LinAbstractObjectiveTo identify risk factors and interventions affecting length of hospitalization (LOH) and clinical outcome…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:59

Experience with cholesteatoma behind an intact tympanic membrane in children
Experience with cholesteatoma behind an intact tympanic membrane in children: Publication date: Available online 19 December 2019Source: American Journal of OtolaryngologyAuthor(s): Urík Milan, Kaliariková Andrea, Machač Josef, Jurajda MichalAbstractIntroductionTo systematically investigate all surgeries for cholesteatoma behind an intact tympanic membrane at our department. To identify predictive factors that can help the surgeon to plan surgery, surgical techniques, and follow-up treatment.Material…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:59

Deep cervical fascia as an anatomical landmark of lingual lymph nodes: An anatomic and histologic study
Deep cervical fascia as an anatomical landmark of lingual lymph nodes: An anatomic and histologic study: Publication date: Available online 18 December 2019Source: Auris Nasus LarynxAuthor(s): Kohtaro Eguchi, Satoru Muro, Koh Miwa, Kumiko Yamaguchi, Keiichi AkitaAbstractObjectivesWe aimed to discuss the definition of lingual lymph nodes based on the deep cervical fascia anatomy.MethodsA total of 11 cadavers were histopathologically evaluated. Specimens were dissected into serial stepwise cross-sections….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:35

Auditory, video head impulse test and vestibular evoked myogenic potentials findings in adults with human immunodeficiency virus
Auditory, video head impulse test and vestibular evoked myogenic potentials findings in adults with human immunodeficiency virus: Even though there is an association between hearing loss and human immunodeficiency virus (HIV), particularly in low- and middle-income countries, further research is needed to investigate the nature of such hearing loss. Likewise, despite documented vestibular alterations in people with HIV, the true occurrence, presentation, and nature of these manifestations are yet…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:34

Management of extracranial arteriovenous malformations of the head and neck
Management of extracranial arteriovenous malformations of the head and neck: The purpose of this study was to review the outcomes of the different therapies for extracranial head and neck arteriovenous malformations (AVMs).AVMs are high-flow congenital vascular anomalies. They are composed of a complex system of vessels directly connecting feeding arteries to draining veins forming a nidus.They may be potentially life-threatening due to progressive symptoms and infiltrative disease. Extracranial…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:34

Machine Learning Model to Help Predict Survival Among Patients With OSCC
Machine Learning Model to Help Predict Survival Among Patients With OSCC: This cohort study describes a model using machine learning to help predict 5-year overall survival among patients with oral squamous cell carcinoma (OSCC) and compares this model with a prediction model created from the TNM (Tumor, Node, Metastasis) clinical and pathologic stage.Omar A. Karadaghy, MD1; Matthew Shew, MD1; Jacob New, PhD2; et alAndrés M. Bur, MD1Author Affiliations1Department of Otolaryngology–Head and Neck Surgery,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:33

Determining Operative Candidacy and Avoiding Regret
Determining Operative Candidacy and Avoiding Regret: Every surgical oncologist bristles when considering whether to offer an operation of questionable benefit. Patient, oncologic, and clinician factors all influence whether a surgery is indicated and how to effectively navigate the necessary preoperative counseling and preparation. The inherent risks and rewards of cancer surgery are magnified when the underlying physical fitness of the patient is in question. Even when dealing with technically feasible…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:32

Association of Preoperative Functional Performance With Outcomes After HNC Surgical Treatment
Association of Preoperative Functional Performance With Outcomes After HNC Surgical Treatment: This cohort study evaluates the association of the addition of adult patients’ functional performance to other important preoperative clinical characteristics with 30-day and 90-day hospital readmissions and overall survival after surgical treatment of head and neck cancer.A Clinical Severity Staging SystemSampat Sindhar, BS1; Dorina Kallogjeri, MD, MPH1,2; Troy S. Wildes, MD3; et alMichael S. Avidan, MBBCh3;…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:32

Treatment of Head and Neck Cancer—Sometimes, Less Is More
Treatment of Head and Neck Cancer—Sometimes, Less Is More: In this issue of JAMA Otolaryngology-Head & Neck Surgery, Saraswathula and colleagues used the Surveillance, Epidemiology, and End Results Program (SEER)–Medicare outcomes and claims database to compare the value of 3 different radiotherapy (RT) regimens (ie, RT alone, RT plus cisplatin, or RT plus cetuximab) administered to patients older than 65 years with locally advanced head and neck cancer (HNC) of the oral cavity, oropharynx, larynx,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:31

Development of a Novel Composite Pathologic Risk Stratification for Surgically Resected HPV-Associated Oropharyngeal Cancer
Development of a Novel Composite Pathologic Risk Stratification for Surgically Resected HPV-Associated Oropharyngeal Cancer: This retrospective cohort study assesses the performance of the traditional pathologic risk stratification system for surgically resected human papillomavirus–associated oropharyngeal squamous cell carcinoma and proposes an alternate composite risk stratification system.John D. Cramer, MD1; Yusuf Dundar, MD1; Jeffrey Hotaling, MD1; et alS. Naweed Raza, MD1; Ho-Sheng Lin, MD1Author…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:30

Care Value for Older Patients Receiving Radiotherapy With or Without Cisplatin or Cetuximab for Head/Neck Cancer
Care Value for Older Patients Receiving Radiotherapy With or Without Cisplatin or Cetuximab for Head/Neck Cancer: This cohort study uses the SEER-Medicare outcomes and claims database to evaluate the quality, outcomes, and costs associated with radiation therapy with or without cisplatin or cetuximab for older adults with stage III to IVB head and neck cancer.Anirudh Saraswathula, BS1; Michelle M. Chen, MD, MHS2; A. Dimitrios Colevas, MD3; et alVasu Divi, MD2Author Affiliations1Stanford University…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:30

Outcomes in Patients 80 Years or Older Undergoing Major Head and Neck Ablation and Reconstruction
Outcomes in Patients 80 Years or Older Undergoing Major Head and Neck Ablation and Reconstruction: This cohort study examines factors associated with 30-day postoperative complications, 90-day mortality, and 90-day functional decline and creates a preoperative risk stratification system for elderly patients undergoing head and neck ablation and reconstruction.Tanya Fancy, MD1; Andrew T. Huang, MD2; Jason I. Kass, MD, PhD3; et alEric D. Lamarre, MD4; Patrick Tassone, MD4; Avinash V. Mantravadi, MD5;…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:28

Association of Older Age and Frailty With Depression and Postoperative Regret About Major Head and Neck Surgery
Association of Older Age and Frailty With Depression and Postoperative Regret About Major Head and Neck Surgery: This cohort study assesses whether age and frailty are associated with preoperative and/or worsening postoperative depression and postoperative decision regret in patients undergoing major head and neck surgery and identifies additional factors associated with depression and decision regret.Carissa M. Thomas, MD, PhD1,2; Michael C. Sklar, MD3; Jie Su, MSc4; et alWei Xu, PhD4,5; John R….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:27

Intraoperative Nerve Monitoring Parameters and Facial Nerve Outcome in Parotidectomy for Benign Disease
Intraoperative Nerve Monitoring Parameters and Facial Nerve Outcome in Parotidectomy for Benign Disease: This case series study analyzes intraoperative facial nerve monitoring data from adult patients who had a parotidectomy operation and identifies the monitoring parameters associated with postoperative nerve weakness.Catherine T. Haring, MD1; Susan E. Ellsperman, MD1; Bruce M. Edwards, AuD1; et alPaul Kileny, PhD1; Deborah Kovatch, MA, MBA, CCC-A1; Gregory R. Mannarelli, AuD1; Melanie A. Meloch,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:26

Risk of Head and Neck Cancer in Patients With Prior Hematologic Malignant Tumors
Risk of Head and Neck Cancer in Patients With Prior Hematologic Malignant Tumors: This study uses Veterans Affairs Corporate Data Warehouse data to examine whether there is an association between prior hematologic malignant tumor and risk of head and neck cancer and assesses the overall survival among these patients.Alia Mowery, BS1; Michael Conlin, MD2; Daniel Clayburgh, MD, PhD2,3Author Affiliations1School of Medicine, Oregon Health and Science University, Portland2Operative Care Division, Portland…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:25

An Enlarging Right Neck Mass in a 25-Year-Old Woman
An Enlarging Right Neck Mass in a 25-Year-Old Woman: Kevin J. Doré, BS1; Prashanthi Divakar, MD2; Konstantinos Linos, MD3Author Affiliations1Geisel School of Medicine at Dartmouth, Hanover, New Hampshire2Section of Otolaryngology, Department of Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire3Department of Pathology, Dartmouth-Hitchcock Medical Center, Lebanon, New HampshireJAMA Otolaryngol Head Neck Surg. Published online December 19, 2019. doi:https://doi.org/10.1001/jamaoto.2019.3842A...

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:23

Unilateral Vocal Fold Immobility After Prolonged Endotracheal Intubation
Unilateral Vocal Fold Immobility After Prolonged Endotracheal Intubation: This subgroup analysis of a cohort study examines the incidence of and risk factors for unilateral vocal fold immobility after more than 12 hours of mechanical ventilation in a medical intensive care unit.

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:20

Permanent Facial Paralysis and Hearing Loss After Aural Irrigation
Permanent Facial Paralysis and Hearing Loss After Aural Irrigation: Removal of cerumen can be achieved through different methods, which each have advantages and disadvantages. One method is aural irrigation, which carries a risk of tympanic perforation or otitis externa. More serious complications are rare but important to recognize. We report the first case of permanent facial palsy and hearing loss following aural irrigation, to our knowledge. This is a unique report of a rare but important complication…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:19

Correlation of mucus inflammatory proteins and olfaction in chronic rhinosinusitis
Correlation of mucus inflammatory proteins and olfaction in chronic rhinosinusitis: BackgroundChronic rhinosinusitis (CRS) is one of the most common causes of olfactory loss, but the pathophysiology underlying olfactory dysfunction in CRS has not been fully elucidated. Previous studies found correlations between olfactory cleft (OC) inflammatory cytokines/chemokines and olfaction in CRS. The purpose of this study was to evaluate the relationship between OC mucus inflammatory proteins and olfaction…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:17

Effect of oxidized cellulose on human respiratory mucosa and submucosa and its implications for endoscopic skull‐base approaches
Effect of oxidized cellulose on human respiratory mucosa and submucosa and its implications for endoscopic skull‐base approaches: BackgroundRegenerated oxidized cellulose (ROC) sheets have gained popularity as an adjunct to a vascularized nasoseptal flap for closure of dural defects after endoscopic endonasal skull‐base approaches (EESBS). However, evidence supporting its impact on the healing process is uncertain. This study was performed to evaluate the impact of ROC on the nasal mucosa and assess…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:17

Risk factors for neo‐osteogenesis in cystic fibrosis and non‒cystic fibrosis chronic rhinosinusitis
Risk factors for neo‐osteogenesis in cystic fibrosis and non‒cystic fibrosis chronic rhinosinusitis: BackgroundThe purpose of this retrospective review was to determine how patient‐related factors and culture data affect neo‐osteogenesis in patients with chronic rhinosinusitis (CRS) and patients with cystic fibrosis (CF) with CRS.MethodsInformation from a database associated with a large tertiary medical center was used to assess adult patients with CF CRS and non‐CF CRS (total, n = 102; CF CRS,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:16

Narrow Band Imaging for lingual tonsil hypertrophy and inflammation, in laryngo-pharyngeal reflux disease
Narrow Band Imaging for lingual tonsil hypertrophy and inflammation, in laryngo-pharyngeal reflux disease: ConclusionsNBI allowed us to identify endoscopically the presence of enlarged lingual tonsil, crypt inflammation and superficial mucosal changes, in patients affected by LPRD.Level of evidence2 (prospective, case –control study). (Source: European Archives of Oto-Rhino-Laryngology)

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:16

Laryngeal adductor reflex hyperexcitability may predict permanent vocal fold paralysis
Laryngeal adductor reflex hyperexcitability may predict permanent vocal fold paralysis: Laryngeal adductor reflex–continuous intraoperative neuromonitoring (LAR‐CIONM) is a novel method of continuous intraoperative neuromonitoring. In contrast to other vagal nerve monitoring techniques, which elicit a laryngeal compound muscle action potential, LAR‐CIONM elicits a laryngeal reflex response (LAR). In 300 nerves at risk monitored with LAR‐CIONM, two patients have had postoperative permanent vocal fold…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:15

Endoscopic Fluorescence‐Guided Surgery for Sinonasal Cancer Using an Antibody‐Dye Conjugate
Endoscopic Fluorescence‐Guided Surgery for Sinonasal Cancer Using an Antibody‐Dye Conjugate: ObjectiveEndoscopic resection of sinonasal squamous cell carcinoma has become the standard of care, but challenges remain in obtaining clear resection margins. The current study evaluated the feasibility of endoscopic fluorescence‐guided surgery (FGS) to improve surgical resection in a human sinus surgical model.MethodsA fluorescence endoscope optimized for near‐infrared (NIR) fluorescence detection was evaluated…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:15

Effects of Chronic Ephedrine Toxicity on Functional Connections, Cell Apoptosis, and CREB-Related Proteins in the Prefrontal Cortex of Rhesus Monkeys
Effects of Chronic Ephedrine Toxicity on Functional Connections, Cell Apoptosis, and CREB-Related Proteins in the Prefrontal Cortex of Rhesus Monkeys: AbstractEphedrine abuse has spread in many parts of the world, severely threatening human health. The mechanism of ephedrine toxicity is still unclear. To explore the possible neural mechanisms of ephedrine toxicity, this study established a non-human primate model of ephedrine exposure, analyzed the functional connectivity changes in its prefrontal…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:15

HMGB1 Mediates Paraquat-Induced Neuroinflammatory Responses via Activating RAGE Signaling Pathway
HMGB1 Mediates Paraquat-Induced Neuroinflammatory Responses via Activating RAGE Signaling Pathway: AbstractParaquat (PQ), a widely characterized neurotoxicant, has been generally accepted as one of the environmental factors in the etiology of Parkinson’s disease (PD). Despite the direct evidence that PQ could induce inflammatory responses in central nervous system, the putative adverse effects of PQ on the neuroimmune interactions have rarely been investigated. High-mobility group box 1 (HMGB1) has…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:15

Inflammatory pseudotumour of the alveolar process of the maxilla as clinical manifestation of IgG4-related disease: a case report and literature review
Inflammatory pseudotumour of the alveolar process of the maxilla as clinical manifestation of IgG4-related disease: a case report and literature review: Publication date: Available online 19 December 2019Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): W.L. Kouwenberg, F.J. Dieleman, S.M. Willems, A.J.W.P. RosenbergAbstractIgG4-related disease (IgG4-RD) is an uncommon immune-mediated condition considered to be a systemic disease, described in multiple organ systems. IgG4-RD…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:14

Speech changes in patients with a full rehabilitation for severe tooth wear, a first evaluation study
Speech changes in patients with a full rehabilitation for severe tooth wear, a first evaluation study: AbstractObjectiveThe aim of this study was to evaluate changes in speech characteristics and self-perceived quality of speech in tooth wear patients, after occlusal rehabilitation.Materials and methodsPatients with tooth wear were included in this study after informed consent. The amount of tooth wear was scored with Tooth Wear Evaluation System (TWES). To assess the perspective of the patient,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:13

The Global Strategy for Women’s, Children’s and Adolescents’ Health : Key focus areas
Key focus areas: In line with the Global Strategy for Women’s, Children’s and Adolescents’ Health, PMNCH focuses on the most vulnerable and marginalized, placing equity at the centre of its work. The Partnership recognizes the substantial impact of health-enhancing sectors on women’s, children’s and adolescents’ health, and engages across sectors to identify links and opportunities to promote greater partner participation in multisectoral knowledge sharing, advocacy, action and accountability to…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:12

Prevalence of QTc prolongation in patients with advanced cancer receiving palliative care
Article in PressPrevalence of QTc prolongation in patients with advanced cancer receiving palliative care – a cause for concern?Janet R. Hardy, BSc, FRACP, MD (Prof)1,∗,’Correspondence information about the author BSc, FRACP, MD Janet R. HardyEmail the author BSc, FRACP, MD Janet R. Hardy, Dr Daniel Bundock2, Dr Jessica Cross2, Kristen Gibbons, Senior Epidemiologist (A/Prof)3, Ross Pinkerton (Prof)4, Dr Korana Kindl5, Phillip Good (A/Prof)5, Jennifer Philip (Prof)6PlumX MetricsDOI: https://doi.org/10.1016/j.jpainsymman.2019.12.356AbstractContextMedications...

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:10

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:28

Steroid use in cervicofacial infection
Steroid use in cervicofacial infection. A Maxillofacial Trainee Research Collaborative (MTReC) project: Introduction: Defining current inpatient management of cervicofacial infections is key to identifying strategies to optimise management. Steroid use is beneficial in peritonsillar abscess and orbital abscess, but there are no studies of steroid use in odontogenic cervicofacial infections. Our previous research identified widespread variation in practice, necessitating a national project to define…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:41

High-throughput methylation profiling of cell-free plasma DNA in head and neck cancer: a pilot study
High-throughput methylation profiling of cell-free plasma DNA in head and neck cancer: a pilot study: Background: A promising platform to provide genetic biomarker led stratification in head and neck cancer (HNSCC) is a liquid biopsy – utilising tumour derived cell-free plasma DNA (cfDNA). One liquid biopsy biomarker that has generated interest is the methylation status of key promotor genes. Tumour DNA methylation patterns in HNSCC have been shown to be biomarkers of treatment response and survival….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:41

Adaptation of an osteotome to produce a predictable sagittal split ramus osteotomy
Adaptation of an osteotome to produce a predictable sagittal split ramus osteotomy: When using an osteotome (as opposed to a technique using a spreader) for bilateral sagittal split osteotomy, it is important to separate the buccal cortex from the intramedullary bone (involving the inferior alveolar neurovascular bundle) before the split by twisting the osteotome).1 A thin sharp osteotome is usually malleted into the groove created on the buccal shelf, and the junction is separated in advance. During…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:40

Comparison of Hogan pharyngeal flap and sphincter pharyngoplasty in postoperative velopharyngeal function
Comparison of Hogan pharyngeal flap and sphincter pharyngoplasty in postoperative velopharyngeal function: The purpose of this study was to compare speech and breathing after sphincter pharyngoplasty and the Hogan pharyngeal flap in the management of cleft-related velopharyngeal insufficiency (VPI). We reviewed 78 patients with VPI who had either the Hogan flap (n=30) or sphincter pharyngoplasty (n=48) between 2009 and 2011. Velopharyngeal function, nasal patency, and speech were compared. In the…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:40

Clinicopathological study of involvement of the submandibular gland in oral squamous cell carcinoma
Clinicopathological study of involvement of the submandibular gland in oral squamous cell carcinoma: Our purpose was to provide a pathological basis for preservation of the submandibular glands during neck dissection for oral squamous cell carcinoma (SCC) by investigating whether intraglandular lymph nodes exist in submandibular glands, and the modes of involvement of submandibular glands in oral SCC. We studied the records of 95 patients with oral SCC (other than that in the floor of the mouth)…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:40

Diphtheritic angina in the tongue and floor of the mouth: unusual presentation
Diphtheritic angina in the tongue and floor of the mouth: unusual presentation: We present the case of a young man with pseudomembranous plaques on the tongue and floor of the mouth, who received systemic and locoregional medical treatment, with a satisfactory outcome after 14 days. (Source: The British Journal of Oral and Maxillofacial Surgery)

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:40

Increasing access to buprenorphine is an important strategy for curtailing the opioid epidemic.
Factors Influencing Buprenorphine Prescribing among Physicians in New York State: Background. Increasing access to buprenorphine is an important strategy for curtailing the opioid epidemic. Research is needed to understand what facilitates prescribing among waivered physicians and how to increase the willingness and capacity to prescribe. This study describes prescribing patterns in a sample of buprenorphine-waivered physicians in New York (NY) in 2016 and examines factors influencing prescribing…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:39

Antioxidant Effect of the Castanea sativa Mill. Leaf Extract on Oxidative Stress Induced upon Human Spermatozoa
Antioxidant Effect of the Castanea sativa Mill. Leaf Extract on Oxidative Stress Induced upon Human Spermatozoa: This study was aimed at evaluating in vitro the effects of a 75% ethanolic extract of leaves of Castanea sativa Mill. (var. Bastarda Rossa, Mount Amiata, Tuscany, Italy) on ejaculated human sperm. Total polyphenols and total flavonoids contained in the extract were determined by a colorimetric assay and HPLC-DAD. The DPPH test and electrochemistry were utilized to study the antioxidant…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:39

Conditioned Medium from Adipose-Derived Stem Cell Inhibits Jurkat Cell Proliferation through TGF-β1 and p38/MAPK Pathway
Conditioned Medium from Adipose-Derived Stem Cell Inhibits Jurkat Cell Proliferation through TGF-β1 and p38/MAPK Pathway: Background. Since the first report on the immunomodulatory and immunosuppressive properties of Adipose-Derived Stem Cells (ADSCs), many studies have elucidated the underlying molecular mechanism of their suppressive activity on mixed lymphocyte reaction (MLR). However, a gap exists in our understanding of the molecular mechanism of ADSC-conditioned medium (ADSC-CM) on MLR. Methods….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:38

Syringic acid promotes proliferation and migration of Schwann cells via down-regulating miR-451-5p
Syringic acid promotes proliferation and migration of Schwann cells via down-regulating miR-451-5p: AbstractSchwann cells are the main force in spontaneous regeneration after peripheral nerve injury. The neurotrophic factors could promote the regeneration, but clinical applications of these factors are limited by some constraints. Hence, searching for new substances to elevate the function of Schwann cells and facilitate the regeneration of nerve is urgently needed. Syringic acid (SA) is a natural…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:38

Disruption of crosstalk between LX-2 and liver cancer stem-like cells from MHCC97H cells by DFOG via inhibiting FOXM1
Disruption of crosstalk between LX-2 and liver cancer stem-like cells from MHCC97H cells by DFOG via inhibiting FOXM1: AbstractHepatic stellate cell (HSC) line LX-2 is activated by liver cancer stem-like cells (LCSLCs) and produces various cytokines that make up most of the hepatocellular carcinoma (HCC) microenvironment. The new genistein derivative, 7-difluoromethoxyl-5,4′-di-n-octylgenistein (DFOG), shows anticancer effects in multiple malignancies by controlling forkhead box M1 (FOXM1). In this…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:38

Exosome-encapsulated miR-505 from ox-LDL-treated vascular endothelial cells aggravates atherosclerosis by inducing NET formation
Exosome-encapsulated miR-505 from ox-LDL-treated vascular endothelial cells aggravates atherosclerosis by inducing NET formation: AbstractNeutrophil extracellular traps (NETs) play an important role in the pathological process of atherosclerosis (AS). This study aims to evaluate whether exosomes from oxidized low-density lipoprotein (ox-LDL)-treated vascular endothelial cells (VECs) aggravate AS by inducing NET formation. Exosomes from the peripheral blood of healthy donors and AS patients (namely…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:37

SRC3 expressed in bone marrow mesenchymal stem cells promotes the development of multiple myeloma
SRC3 expressed in bone marrow mesenchymal stem cells promotes the development of multiple myeloma: AbstractSRC3 plays critical roles in various biological processes of diseases, including proliferation, apoptosis, migration, and cell cycle arrest. However, the effect of SRC3 expression in mesenchymal stem cells (MSCs) on multiple myeloma (MM) is not clear yet. In our study, MSCs (MSC-SRC3, MSC-SRC3−/−) and MM cells were co-cultured in a direct or indirect way. The proliferation of MM cells was studied…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:37

Expression of Nup93 is associated with the proliferation, migration and invasion capacity of cervical cancer cells
Expression of Nup93 is associated with the proliferation, migration and invasion capacity of cervical cancer cells: AbstractCervical cancer is a prevalent and devastating malignancy in females worldwide. Nucleoporin 93 (Nup93), a member of the nuclear pore complex, plays an important role in transport across the nuclear pore. Several nucleoporins have been linked to cancer. However, the oncogenic role and underlying mechanism of Nup93 in cervical cancer development have not been reported. In this…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:37

A novel protein L-cofilin2 identified in Lampetra morii with roles of immune response and cell proliferation promotion
A novel protein L-cofilin2 identified in Lampetra morii with roles of immune response and cell proliferation promotion: Cofilin2, an actin-binding protein, is expressed in many eukaryotic cells. It binds to and depolymerizes the actin filaments, and its activity is regulated by phosphorylation, dephosphorylation, and pH [1]. Cofilins have been reported to have multiple functions, including cytokinesis, cell locomotion [2], cellular stress responses [3], and pathological situations [4]. Under normal…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:37

Decreased expression of piR-35413 in human papillary thyroid cancer
Decreased expression of piR-35413 in human papillary thyroid cancer: The piRNAs (PIWI-interacting RNAs) are ~26–31 nt in length and are very similar to but little longer than the microRNAs (miRNAs) in size [1]. Since the discovery of the first piRNA in 2006, the number of piRNA sequences has now reached 173 million from 264 datasets in 21 organisms [2]. And, there are 8,438,265 piRNAs identified in the human genome, which far exceeds the total number of miRNAs (~2000) [2], suggesting that piRNAs…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:36

The expression changes of circular RNAs between LH + 2 and LH + 7 human endometrium
The expression changes of circular RNAs between LH + 2 and LH + 7 human endometrium: Compatible endometrial receptivity is essential for successful implantation. The underlying molecular mechanisms are continuously explored in assisted reproduction field, focusing on the protein-encoding genes and microRNAs (miRNAs) [1,2]. However, the effects of circular RNAs (circRNAs) on endometrial receptivity, as well as the regulatory mechanisms, are poorly understood. circRNAs are a special class of non-coding…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:36

Quercetin improves endothelial insulin sensitivity in obese by inhibiting Drp1 phosphorylation at serine 616 and mitochondrial fragmentation
Quercetin improves endothelial insulin sensitivity in obese mice by inhibiting Drp1 phosphorylation at serine 616 and mitochondrial fragmentation: AbstractStudies have shown that endothelial insulin resistance induced by oxidative stress contributes to vascular dysfunction in metabolic disorders. Quercetin, a natural antioxidant, has been recently shown to exert protective effects on endothelial function. However, the effects of quercetin on endothelial insulin resistance and its underlying mechanism…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:36

Accuracy of Ultrasound in Diagnosis of Pneumothorax: A Comparison between Neonates and Adults—A Systematic Review and Meta-Analysis
Accuracy of Ultrasound in Diagnosis of Pneumothorax: A Comparison between Neonates and Adults—A Systematic Review and Meta-Analysis: Objective. The present systematic review and meta-analysis were conducted to investigate the accuracy of ultrasound in the diagnosis of pneumothorax in neonates and adults. Method. The searches were conducted by two independent researchers (MS and HD) to find the relevant studies published from 01/01/2009 until the end of 01/01/2019. We searched for published literature…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:35

Steps to Develop a Mobile App for Pain Assessment of Cancer Patients: A Usability Study
Steps to Develop a Mobile App for Pain Assessment of Cancer Patients: A Usability Study: Health-related mobile apps have the potential to allow patients and providers to proactively and responsibly manage pain together. However, there is a gap between the science of pain and current mobile apps. To develop a prototype science-based pain assessment mobile app (PainSmart) for Android smartphones, pain assessment tasks were extracted from a clinical guideline. These tasks were then converted to activity…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:35

Visualizations Integrated Into Consumer Health Technologies Support Self-management of Chronic Diseases: A Systematic Review
Visualizations Integrated Into Consumer Health Technologies Support Self-management of Chronic Diseases: A Systematic Review: While chronic diseases remain a global problem, visualizations of data and information are a potential solution to assist patients with chronic disease in communication, self-management, and decision making. The purpose of this systematic review is to synthesize evidence regarding data and information visualizations integrated into consumer health informatics solutions for…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:35

Using an Evidence-Based Approach for Electronic Health Record Downtime Education in Nurse Onboarding
Using an Evidence-Based Approach for Electronic Health Record Downtime Education in Nurse Onboarding: Electronic health record systems have been widely implemented throughout healthcare settings over the last few years, and nurses rely on these systems to obtain information about patients, make clinical decisions, and deliver safe and appropriate care. Health information technology systems have electronic health record downtime episodes both due to scheduled maintenance and unforeseen circumstances….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:34

The relationship of trauma exposure to heart rate variability during wake and sleep in midlife women
The relationship of trauma exposure to heart rate variability during wake and sleep in midlife women: AbstractTraumatic experiences are common and linked to cardiovascular disease (CVD) risk, yet the mechanisms underlying these relationships is less well understood. Few studies have examined trauma exposure and its relation to autonomic influence over cardiac function, a potential pathway linking trauma exposure to CVD risk. Investigating autonomic influence over cardiac function during both wake…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:34

PrP is a central player in toxicity mediated by soluble aggregates of neurodegeneration-causing proteins
PrP is a central player in toxicity mediated by soluble aggregates of neurodegeneration-causing proteins: AbstractNeurodegenerative diseases are an enormous public health problem, affecting tens of millions of people worldwide. Nearly all of these diseases are characterized by oligomerization and fibrillization of neuronal proteins, and there is great interest in therapeutic targeting of these aggregates. Here, we show that soluble aggregates of α-synuclein and tau bind to plate-immobilized PrP in…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:34

Evaluation of thrombotic events in patients with immune thrombocytopenia
Evaluation of thrombotic events in patients with immune thrombocytopenia: AbstractImmune thrombocytopenia (ITP) has been reported to be associated with thrombotic events. The incidence of thrombosis in 303 newly diagnosed ITP patients in our institute between 2000 and 2016 was retrospectively reviewed. During a median follow-up of 3.6 years, 16 thrombotic events (12 arterial and four venous) occurred. The median platelet count at thrombotic events was 102 × 109/l. At 10 years, the cumulative thrombosis…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:34

Lipegfilgrastim in multiple myeloma patients after high dose melphalan and autologous stem cell transplant
A comparative effectiveness study of lipegfilgrastim in multiple myeloma patients after high dose melphalan and autologous stem cell transplant: AbstractG-CSF administration after high-dose chemotherapy and autologous stem cell transplantation (ASCT) has been shown to expedite neutrophil recovery. Several studies comparing filgrastim and pegfilgrastim in the post-ASCT setting concluded that the two are at least equally effective. Lipegfilgrastim (LIP) is a new long-acting, once-per-cycle G-CSF. This…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:33

Effects of vitamin D in an animal model of Alzheimer’s disease: behavioral assessment with biochemical investigation of Hippocampus and serum
Effects of vitamin D in an animal model of Alzheimer’s disease: behavioral assessment with biochemical investigation of Hippocampus and serum: AbstractRegulatory role of vitamin D (VitD) in cognitive memory and learning has been proposed. Here, we examine the behavioral and biochemical effects of VitD in Alzheimer’s disease (AD), as the most common form of dementia, in male Wistar rats. Animals (n = 48) were randomly divided into six groups: control, sham solvent, sham surgery, VitD (by intraperitoneal…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:33

Protective effects of Chrysin against memory impairment, cerebral hyperemia and oxidative stress after cerebral hypoperfusion and reperfusion in rats
Protective effects of Chrysin against memory impairment, cerebral hyperemia and oxidative stress after cerebral hypoperfusion and reperfusion in rats: AbstractStroke is devastating and a leading cause of morbidity and mortality worldwide. Cerebral ischemia-reperfusion and its subsequent reactive hyperemia lead to neuronal damage in the hippocampus and cognitive decline. Chrysin (5, 7-dihydroxyflavone) is a well-known member of the flavonoid family with antioxidant and neuroprotective effects. Therefore,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:33

Cytokine/chemokine dysregulation in progressive MS patient is apparent and can be modulated by calpain inhibition
Cytokine/chemokine dysregulation in progressive MS patient is apparent and can be modulated by calpain inhibition: AbstractThis study examines the cytokine/chemokine profile of a 62-year-old African American male with progressive multiple sclerosis (MS). MRI images of the MS patient demonstrated generalized white matter involvement with multiple lesions in the periventricular area. A 42-plex Discovery Assay® (Eve Technologies) of the patient’s plasma and peripheral blood mononuclear cells (PBMCs)…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:33

Detection and quantification of New psychoactive substances (NPS)—such as synthetic cathinones and piperazines—.
Detection and quantification of synthetic cathinones and selected piperazines in hair by LC-MS/MS: AbstractNew psychoactive substances (NPS)—such as synthetic cathinones and piperazines—are defined as substances designed to replicate the effects of traditional illegal drugs, including cocaine, ecstasy and amphetamines. These substances are known to potentially be much more potent than their analogs. In the past, there were many poisonings and deaths associated with NPS. Because of this, NPS identification…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:33

Simultaneous Cricoid and Thyroid Cartilage Metastases from Prostatic Adenocarcinoma on 68 Ga-PSMA PET/CT
An Unusual Case of Simultaneous Cricoid and Thyroid Cartilage Metastases from Prostatic Adenocarcinoma on 68 Ga-PSMA PET/CT: AbstractAlthough prostate cancer can metastasize to any part of the body, laryngeal cartilage metastasis is extremely rare and few cases have been published so far. Here we present the case of a 65-year-old male patient, recently diagnosed with prostate adenocarcinoma, referred for staging with 68Ga-PSMA PET/CT. He was found to have extensive skeletal metastasis along with…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:32

Neoadjuvant Chemotherapy Benefits Survival in High-Grade Upper Tract Urothelial Carcinoma: A Propensity Score-Based Analysis
Neoadjuvant Chemotherapy Benefits Survival in High-Grade Upper Tract Urothelial Carcinoma: A Propensity Score-Based Analysis: AbstractBackgroundTo evaluate the benefit of neoadjuvant chemotherapy (NAC) for survival in high-grade upper tract urothelial carcinoma (UTUC), a propensity score-based analysis was performed with high-grade UTUC patients from multiple urologic centers.MethodsFrom three urologic centers, 48 high-grade UTUC patients who received chemotherapy followed by surgery (NAC group)…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:32

Intra fractional 6D head movement increases with time of mask fixation during stereotactic intracranial RT-sessions
Intra fractional 6D head movement increases with time of mask fixation during stereotactic intracranial RT-sessions: AbstractBackgroundThe present study investigates the intrafractional accuracy of a frameless thermoplastic mask used for head immobilization during stereotactic radiotherapy. Non-invasive masks cannot completely prohibit head movements. Previous studies attempted to estimate the magnitude of intrafractional inaccuracy by means of pre- and postfractional measurements only. However,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:31

Clinical features and treatment outcomes of limited-stage mantle cell lymphoma: Consortium for Improving Survival of Lymphoma report
Clinical features and treatment outcomes of limited-stage mantle cell lymphoma: Consortium for Improving Survival of Lymphoma report: AbstractLimited-stage (Ann Arbor stage I or II) mantle cell lymphoma (MCL) is an extremely rare disease. Thus, there is little data on the clinical features and treatment outcomes of patients with early-stage MCL. We examined consecutive stage I or II MCL 41 cases diagnosed between 2000 and 2016 in 16 institutions of the Consortium for Improving Survival of Lymphoma…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:31

CD73 expression and pathologic response to neoadjuvant chemotherapy in triple negative breast cancer
CD73 expression and pathologic response to neoadjuvant chemotherapy in triple negative breast cancer: AbstractThe immune system plays a key role in tumor surveillance and escape. Recently, CD73 has been proposed as a prognostic biomarker associated with disease-free survival and overall survival in triple negative breast cancer (TNBC). In this study, we investigated the role of both CD73 expression and stromal tumor–infiltrating lymphocytes (TILs) in predicting the pathologic response of TNBC to…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:31

Intensity-modulated radiotherapy is superior to three-dimensional conformal radiotherapy in the trimodality management of muscle-invasive bladder cancer with daily cone beam computed tomography optimization
Intensity-modulated radiotherapy is superior to three-dimensional conformal radiotherapy in the trimodality management of muscle-invasive bladder cancer with daily cone beam computed tomography optimization: AbstractObjectiveIntensity-modulated radiation therapy (IMRT) using a volumetric-modulated arc therapy technique may offer dosimetric and clinical benefits compared to the historical standard of care 3D conformal radiotherapy (3D-CRT) in definitive treatment of bladder cancer. We hypothesized…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:31

Role of VEGFs in metabolic disorders
Role of VEGFs in metabolic disorders: AbstractObesity and metabolic disorders are important public health problems. In this review, the role of vasculature network and VEGF in the adipose tissue maintenance and supplementation is discussed. Angiogenesis is a key process implicated in regulation of tissues homeostasis. Dysregulation of new blood vessels formation may be crucial and contribute to the onset of several pathological conditions, including metabolic syndrome-associated disorders. Adipose…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:30

Robot motion design using bunraku emotional expressions – focusing on Jo-Ha-Kyū in sounds and movements
Robot motion design using bunraku emotional expressions – focusing on Jo-Ha-Kyū in sounds and movements: AbstractOne of the UNESCO intangible cultural heritages Bunraku puppets can play one of the most beautiful puppet motions in the world. The Bunraku puppet motions can express emotions without the so-called ‘Uncanny Valley.’ We try to convert these emotional motions into robot affective motions so that robots can interact with human beings more comfortable. In so doing, in the present paper, we…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:30

Middle East respiratory syndrome coronavirus (MERS-CoV) – The Kingdom of Saudi Arabia
Middle East respiratory syndrome coronavirus (MERS-CoV) – The Kingdom of Saudi Arabia: From 1 through 30 November 2019, the National IHR Focal Point of Saudi Arabia reported 10 additional cases of Middle East respiratory syndrome (MERS-CoV) infection and one associated deaths. The cases were reported from Riyadh (4), Madinah (2), Al-Qassim (1), Assir (1), Taif (1), and Makkah (1) regions.The link below provides details of the 10 reported cases:

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:29

Pre- and intraoperative acoustic and functional assessment of the novel APrevent® VOIS implant during routine medialization thyroplasty.
Pre- and intraoperative acoustic and functional assessment of the novel APrevent® VOIS implant during routine medialization thyroplasty.: Related ArticlesPre- and intraoperative acoustic and functional assessment of the novel APrevent® VOIS implant during routine medialization thyroplasty.Eur Arch Otorhinolaryngol. 2019 Dec 16;:Authors: Ho GY, Leonhard M, Denk-Linnert DM, Schneider-Stickler BAbstract PURPOSE: Persistent unilateral vocal fold paralysis (UFVP) with glottal insufficiency often…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:28

Psychiatric Distress as a Common Risk Factor for Tinnitus and Joint Pain: A National Population-Based Survey.
Psychiatric Distress as a Common Risk Factor for Tinnitus and Joint Pain: A National Population-Based Survey.: Related ArticlesPsychiatric Distress as a Common Risk Factor for Tinnitus and Joint Pain: A National Population-Based Survey.Clin Exp Otorhinolaryngol. 2019 Dec 18;:Authors: Park E, Kim H, Choi IH, Han HM, Han K, Jung HH, Im GJAbstract Objectives: This study aimed to investigate the relationship between tinnitus and joint pain from representative samples of Koreans. Methods:…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:28

Hemostasis of idiopathic recurrent epistaxis in children with microwave ablation: a prospective pilot case series
Hemostasis of idiopathic recurrent epistaxis in children with microwave ablation: a prospective pilot case series: AbstractObjectiveWe evaluated microwave ablation (MWA) for treatment of idiopathic recurrent anterior epistaxis (RAE) in children, in terms of technical feasibility, efficacy, and safety.Study designA prospective pilot case series.SettingTertiary university hospital.MethodsChildren with idiopathic RAE were treated with endoscopic MWA and reevaluated at 1 and 4 weeks and at 6 months thereafter….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:28

Headache after septoplasty
Headache after septoplasty: Publication date: Available online 18 December 2019Figures (2)Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): S. Chastanet, D. Goga, A. Paré

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:26

Nasopharyngeal Cultures in Children; When, What and Why?
Nasopharyngeal Cultures in Children; When, What and Why?: Publication date: Available online 17 December 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Samuel Flyman, Ann Hermansson, Marie Gisselsson SolénAbstractIntroductionNasopharyngeal cultures are commonly used to determine the causative bacteria in upper airway infections. However, several bacteria can occupy the nasopharynx simultaneously and most healthy children are asymptomatic carriers of presumptive pathogens….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:23

Sudden sensorineural hearing loss (SSNHL) can be the presenting symptom of vestibular schwannoma (VS). Usually, steroidal treatment is given before magnetic resonance imaging (MRI) is performed.
Hearing Improvement after Sudden Sensorineural Hearing Loss as a Predictor of Vestibular Schwannoma: Introduction: Sudden sensorineural hearing loss (SSNHL) can be the presenting symptom of vestibular schwannoma (VS). Usually, steroidal treatment is given before magnetic resonance imaging (MRI) is performed. Objectives: The aim of this study was to investigate whether there is a different pattern of steroidal treatment response after SSNHL in patients with and without a VS, in order to determine…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:22

Pharyngeal motility in patients submitted to type I thyroplasty
Pharyngeal motility in patients submitted to type I thyroplasty: Publication date: Available online 18 December 2019Source: Brazilian Journal of OtorhinolaryngologyAuthor(s): Bruno Rezende Pinna, Fernando A.M. Herbella, Noemi de BiaseAbstractIntroductionType 1 thyroplasty is performed to improve glottis closure as well as dysphagic symptoms in patients with unilateral vocal fold immobility.ObjectivesThis study aims to compare the motility of the pharynx and upper esophageal sphincter in patients…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:22

Pediatric nasal tip abscesses
Pediatric nasal tip abscesses: We report on 7 children/teenagers who presented with an advanced nasal tip abscess that required intravenous antibiotics and surgical drainage, despite adequate pre-admission antibiotic therapy with amoxicillin/clavulanic acid or cephalosporins. Cultures were positive forStaphylococcus aureus, that was clindamycin-resistant but TMP/SMX sensitive. (Source: European Archives of Oto-Rhino-Laryngology)

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:21

Deep cervical fascia as an anatomical landmark of lingual lymph nodes: An anatomic and histologic study
Deep cervical fascia as an anatomical landmark of lingual lymph nodes: An anatomic and histologic study: AbstractObjectivesWe aimed to discuss the definition of lingual lymph nodes based on the deep cervical fascia anatomy.MethodsA total of 11 cadavers were histopathologically evaluated. Specimens were dissected into serial stepwise cross-sections. The deep cervical fascia and lymph nodes were evaluated by staining the cross-sections with Elastica van Gieson and hematoxylin and eosin stains, respectively….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:20

Hemostasis of idiopathic recurrent epistaxis in children with microwave ablation: a prospective pilot case series
Hemostasis of idiopathic recurrent epistaxis in children with microwave ablation: a prospective pilot case series: We evaluated microwave ablation (MWA) for treatment of idiopathic recurrent anterior epistaxis (RAE) in children, in terms of technical feasibility, efficacy, and safety. Hemostasis of idiopathic recurrent epistaxis in children with microwave ablation: a prospective pilot case seriesZheng-cai Lou Journal of Otolaryngology – Head & Neck Surgery volume 48, Article number: 72 (2019)…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:18

Balloon dilatation for paediatric airway stenosis: evidence from the UK Airway Intervention Registry
Balloon dilatation for paediatric airway stenosis: evidence from the UK Airway Intervention Registry: AbstractObjectivesTo assess the safety and efficacy in routine clinical practice of balloon dilatation procedures in the treatment of paediatric airway stenosis.DesignObservational data collection in prospective online research databaseSettingAcute NHS Trusts with ENT department undertaking complex paediatric airway workParticipants: Children (<18) undergoing balloon dilatation treatment for airway…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:16

The effect of three‐dimensional visualization on performance in endoscopic endonasal surgery: a clinical training study using surgical navigation for movement analysis in a randomized cross over design
The effect of three‐dimensional visualization on performance in endoscopic endonasal surgery: a clinical training study using surgical navigation for movement analysis in a randomized cross over design: AbstractObjectivesEndoscopic imaging techniques and endoscopic endonasal surgery (EES) expertise have evolved rapidly. Only few studies have assessed the effect of three‐dimensional (3D) endoscopy on endoscopic sinus surgery (ESS). The present study aimed to objectively and subjectively assess the…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:16

Atraumatic compression of the pinna – an alternative application of the external nasal splint
Technical note: Atraumatic compression of the pinna – an alternative application of the external nasal splint: AbstractKeloid scars represent a pathological dermal response to injury characterised by aberrant fibroblast proliferation and resultant overproduction of collagen1. Distinct from hypertrophic scars, keloids infiltrate surrounding normal tissue and rarely regress.2 Keloid lesions extend beyond the margins of the original injury and may cause significant functional, cosmetic and psychological…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:16

Flexible laser Sphenopalatine artery ligation: an alternative to the classic approach
Flexible laser Sphenopalatine artery ligation: an alternative to the classic approach: AbstractEpistaxis is one of the most common ENT emergencies and also a well‐known reason for hospital admission. About 5‐15% of hospital admissions will finally require surgical treatment, with the most preferable method being ligation of the sphenopalatine artery (SPA)1. We are aiming to present an alternative to the classic approach which may help the surgeon overcome any obstacles leading to difficult access…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:15

Prognostic values of preoperative platelet‐to‐lymphocyte ratio (PLR) and platelet‐related indices in advanced hypopharyngeal squamous cell carcinoma
Prognostic values of preoperative platelet‐to‐lymphocyte ratio (PLR) and platelet‐related indices in advanced hypopharyngeal squamous cell carcinoma: AbstractObjectivesTo investigate the prognostic values of preoperative platelet‐to‐lymphocyte ratio (PLR) and platelet‐related indices in advanced hypopharyngeal squamous cell carcinoma (HPSCC).MethodsThe data of 247 eligible advanced HPSCC patients were reviewed retrospectively. Pretreatment hematological parameters were categorized into 2 groups based…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:15

A novel water occlusion test for disorders causing pulsatile tinnitus: Our experience in 32 patients
A novel water occlusion test for disorders causing pulsatile tinnitus: Our experience in 32 patients: AbstractPulsatile tinnitus (PT) originates mainly from the vascular structures near the cochlea and the vascular sound is believed to be transmitted to the cochlea by bony or vascular structures.Digital pressure test over the internal jugular vein ipsilateral to PT side is a simple test for differentiating venous from arterial PT by lessening venous flow.Pulsation of dehiscent venous sinus wall itself…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:15

Jervell and Lange-Nielsen syndrome is a rare autosomal recessive disease characterized by congenital sensorineural deafness and significant QT interval prolongation.
Cochlear Implantation in Congenital Long-QT Syndrome: A Comprehensive Study.: Related ArticlesCochlear Implantation in Congenital Long-QT Syndrome: A Comprehensive Study.J Int Adv Otol. 2019 Dec;15(3):352-357Authors: Anto R, Maheswari S, Vadivu S, Kameswaran MAbstract OBJECTIVES: Jervell and Lange-Nielsen syndrome is a rare autosomal recessive disease characterized by congenital sensorineural deafness and significant QT interval prolongation. Aims were to study the prevalence of long QT in…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:14

GJB2, GJB3, and GJB6 Gene Mutations in Patients with Hereditary Non-Syndromic Hearing Loss
The Analysis of GJB2, GJB3, and GJB6 Gene Mutations in Patients with Hereditary Non-Syndromic Hearing Loss Living in Sivas.: Related ArticlesThe Analysis of GJB2, GJB3, and GJB6 Gene Mutations in Patients with Hereditary Non-Syndromic Hearing Loss Living in Sivas.J Int Adv Otol. 2019 Dec;15(3):373-378Authors: Küçük Kurtulgan H, Altuntaş EE, Yıldırım ME, Özdemir Ö, Bağcı B, Sezgin İAbstract OBJECTIVES: The aim of the present study was to investigate the presence of GJB2, GJB3, and GJB6 gene…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:13

The Microbiome in the Adenoids of Children with Otitis Media with Effusion.
Analysis of the Microbiome in the Adenoids of Korean Children with Otitis Media with Effusion.: Related ArticlesAnalysis of the Microbiome in the Adenoids of Korean Children with Otitis Media with Effusion.J Int Adv Otol. 2019 Dec;15(3):379-385Authors: Kim SK, Hong SJ, Pak KH, Hong SMAbstract OBJECTIVES: The adenoid pad, which is located between the orifice of the Eustachian tube (ET) and posterior nasal cavity, can affect the development of otitis media with effusion (OME) because of its…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:12

Clinical Characteristics and Treatment Outcomes of Congenital Cholesteatoma.
Clinical Characteristics and Treatment Outcomes of Congenital Cholesteatoma.: Related ArticlesClinical Characteristics and Treatment Outcomes of Congenital Cholesteatoma.J Int Adv Otol. 2019 Dec;15(3):386-390Authors: Song IS, Han WG, Lim KH, Nam KJ, Yoo MH, Rah YC, Choi JAbstract OBJECTIVES: Since its introduction in 2002, the staging system for congenital cholesteatoma, as defined by Potsic, has been used widely owing to its simplicity and predictability. The aim of the present study was…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:12

Endoscope-Assisted Surgery for Petrous Bone Cholesteatoma with Hearing Preservation.
Endoscope-Assisted Surgery for Petrous Bone Cholesteatoma with Hearing Preservation.: Related ArticlesEndoscope-Assisted Surgery for Petrous Bone Cholesteatoma with Hearing Preservation.J Int Adv Otol. 2019 Dec;15(3):391-395Authors: Orhan KS, Çelik M, Polat B, Aydemir L, Aydoseli A, Sencer A, Güldiken YAbstract OBJECTIVES: Petrous bone cholesteatoma is a rare pathologic entity and may be a difficult surgical challenge because of potential involvement of the facial nerve, carotid artery, dura…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:12

Health Related Quality of Life after the Bony Obliteration Tympanoplasty for COM with Cholesteatoma using the COMQ12 – A Disease Specific PROM.
Health Related Quality of Life after the Bony Obliteration Tympanoplasty for COM with Cholesteatoma using the COMQ12 – A Disease Specific PROM.: Related ArticlesHealth Related Quality of Life after the Bony Obliteration Tympanoplasty for COM with Cholesteatoma using the COMQ12 – A Disease Specific PROM.J Int Adv Otol. 2019 Dec;15(3):396-399Authors: Baetens W, Dinther JV, Vanspauwen R, Maryn Y, Zarowski A, Offeciers EAbstract OBJECTIVES: This study aimed to investigate the effect of canal…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:12

Mastoid Obliteration with Synthetic Materials
Mastoid Obliteration with Synthetic Materials: A Review of the Literature.: Related ArticlesMastoid Obliteration with Synthetic Materials: A Review of the Literature.J Int Adv Otol. 2019 Dec;15(3):400-404Authors: Skoulakis C, Koltsidopoulos P, Iyer A, Kontorinis GAbstract Canal wall down mastoidectomy is a surgical technique used for the eradication of middle ear disease. The remaining large mastoid bowl is associated with a number of issues; one of the main techniques that have been developed…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:12

Prevention of Craniofacial Pain Secondary to Harvesting of Temporalis Fascia – A Novel Technique.
Prevention of Craniofacial Pain Secondary to Harvesting of Temporalis Fascia – A Novel Technique.: Related ArticlesPrevention of Craniofacial Pain Secondary to Harvesting of Temporalis Fascia – A Novel Technique.J Int Adv Otol. 2019 Dec;15(3):405-408Authors: Bhat VK, Ajur S, Bongale KR, Sachidananda RAbstract OBJECTIVES: A lesser known after effect of harvesting temporalis fascia is the post-surgical craniofacial pain. The aim of the study was to evaluate this pain after tympanomastoid surgeries…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:11

The Comparison of the Right and Left Sigmoid Sinus Cross-Sectional Areas in Fetal Period and the Factors Affecting the Venous Dominance.
The Comparison of the Right and Left Sigmoid Sinus Cross-Sectional Areas in Fetal Period and the Factors Affecting the Venous Dominance.: Related ArticlesThe Comparison of the Right and Left Sigmoid Sinus Cross-Sectional Areas in Fetal Period and the Factors Affecting the Venous Dominance.J Int Adv Otol. 2019 Dec;15(3):409-414Authors: Özalp H, Aktekin M, Hamzaoğlu V, Vayisoğlu Y, Karataş MA, Karşıyaka D, Uzmansel D, Bozdoğan Arpacı R, Cayan F, Eti CM, Kanık A, Baskan FC, Aladağ ZC, Ertaş E, Dağtekin…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:11

Surgical Outcomes of Intratemporal Facial Nerve Schwannomas According to Facial Nerve Manipulation.
Surgical Outcomes of Intratemporal Facial Nerve Schwannomas According to Facial Nerve Manipulation.: Related ArticlesSurgical Outcomes of Intratemporal Facial Nerve Schwannomas According to Facial Nerve Manipulation.J Int Adv Otol. 2019 Dec;15(3):415-419Authors: Kang WS, Han JJ, Rhee J, Lee JH, Koo JW, Chung JWAbstract OBJECTIVES: The aim of this study was to evaluate the preoperative and postoperative facial nerve (FN) function in patients with FN schwannoma (FNS) and analyze the duration…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:11

Efficacy of Epley Maneuver on Quality of Life of Elderly Patients with Subjective BPPV.
Efficacy of Epley Maneuver on Quality of Life of Elderly Patients with Subjective BPPV.: Related ArticlesEfficacy of Epley Maneuver on Quality of Life of Elderly Patients with Subjective BPPV.J Int Adv Otol. 2019 Dec;15(3):420-424Authors: Uz U, Uz D, Akdal G, Çelik OAbstract OBJECTIVES: This study aimed to evaluate the efficacy of the repositioning maneuver on quality of life in elderly patients with dizziness and/or vertigo. MATERIALS AND METHODS: This controlled, prospective randomized…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:11

Head-Shaking Nystagmus in the Early Stage of Unilateral Meniere’s Disease.
Head-Shaking Nystagmus in the Early Stage of Unilateral Meniere’s Disease.: Related ArticlesHead-Shaking Nystagmus in the Early Stage of Unilateral Meniere’s Disease.J Int Adv Otol. 2019 Dec;15(3):425-430Authors: Stadio AD, Ricci G, Ralli M, Paolo T, Agostini G, Faralli MAbstract OBJECTIVES: The aim of the present study was to evaluate the ability of head-shaking nystagmus (HSNy), evoked after the resolution of a vertigo spell, to predict an imminent crisis in the early stage of Meniere’s…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:10

A New Application of CBCT Image Fusion in Temporal Bone Studies.
A New Application of CBCT Image Fusion in Temporal Bone Studies.: Related ArticlesA New Application of CBCT Image Fusion in Temporal Bone Studies.J Int Adv Otol. 2019 Dec;15(3):431-435Authors: Iso-Mustajärvi M, Sipari S, Lehtimäki A, Tervaniemi J, Löppönen H, Dietz AAbstract OBJECTIVES: Temporal bone (TB) studies are essential during the development of new arrays. Postoperative cochlear histology is still regarded as golden standard for the assessment of electrode localization and trauma…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:07

Menière’s Disease and Caloric Stimulation: Abnormalities of the thermally induced nystagmus on the affected side characterize most patients with MD, but only "SPV" alterations are common in the early stages. An increasing severity of the cochlear involvement progressively reflects also on the "frequency" parameter. Detecting a dissociation between these two parameters could represent an instrumental marker of the early forms of MD.
Menière’s Disease and Caloric Stimulation: Some News from an Old Test.: Related ArticlesMenière’s Disease and Caloric Stimulation: Some News from an Old Test.J Int Adv Otol. 2019 Dec;15(3):442-446Authors: Cerchiai N, Navari E, Miccoli M, Casani APAbstract OBJECTIVES: The aim of the present study was to improve the instrumental diagnosis of assessing Menière’s disease (MD) if the frequency and slow-phase velocity (SPV) of the thermally induced nystagmus analyzed through the caloric vestibular…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:07

The Dizziness Handicap Inventory
Validation and Factor Analysis of the Lithuanian Version of the Dizziness Handicap Inventory.: Related ArticlesValidation and Factor Analysis of the Lithuanian Version of the Dizziness Handicap Inventory.J Int Adv Otol. 2019 Dec;15(3):447-453Authors: Valančius D, Ulytė A, Masiliūnas R, Paškonienė A, Ulozienė I, Kaski D, Vaicekauskienė L, Lesinskas E, Jatužis D, Ryliškienė KAbstract OBJECTIVES: This study aimed to validate the Lithuanian version of the Dizziness Handicap Inventory (DHI-L),…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:07

Muckle-Wells syndrome (MWS), a subclass of cryopyrin-associated periodic syndrome (CAPS), sometimes includes complications of bilateral progressive sensorineural hearing loss
The Long-Term Efficacy of Cochlear Implantation for Hearing Loss in Muckel-Wells Syndrome.: Related ArticlesThe Long-Term Efficacy of Cochlear Implantation for Hearing Loss in Muckel-Wells Syndrome.J Int Adv Otol. 2019 Dec;15(3):454-458Authors: Ogawa B, Aoki M, Ohnishi H, Ohashi T, Hayashi H, Kuze B, Ito YAbstract Muckle-Wells syndrome (MWS), a subclass of cryopyrin-associated periodic syndrome (CAPS), sometimes includes complications of bilateral progressive sensorineural hearing loss. A…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:06

Bromate Intoxication-Induced Bilateral Deafness
Cochlear Implantation after Bromate Intoxication-Induced Bilateral Deafness: A Case Report.: Related ArticlesCochlear Implantation after Bromate Intoxication-Induced Bilateral Deafness: A Case Report.J Int Adv Otol. 2019 Dec;15(3):459-462Authors: Sung-Won C, Youngmo CAbstract Hearing loss is a common consequence of the strong acidosis induced by bromate poisoning. Partial hearing recovery has been achieved through medical or rehabilitative therapy but reports of surgical otology treatment…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:06

Cryptic Early Gastric Carcinoma in Gastric Stump: Challenges in Diagnostic Evaluation
Cryptic Early Gastric Carcinoma in Gastric Stump: Challenges in Diagnostic Evaluation: Partial gastrectomy, performed for any indication, is a well-recognized risk factor for carcinoma developing in the gastric remnant (so-called “gastric stump carcinoma”). In symptomatic patients with gastro-enteric anastomosis, it is a common practice to endoscopically evaluate the patency and the status of the anastomosis and procure biopsy samples when endoscopic abnormalities are noted. We describe a case with…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:05

Fatal chronic meningitis caused by Candida dubliniensis after liver transplantation
Fatal chronic meningitis caused by <em>Candida dubliniensis</em> after liver transplantation: Publication date: Available online 17 December 2019Source: Medical Mycology Case ReportsAuthor(s): Mariam Gheshlaghi, Jannik Helweg-LarsenAbstractWe report a case of fatal chronic Candida dubliniensis meningitis complicated by severe hydrocephalus secondary to liver transplantation, in which diagnosis was considerably delayed.Candida dubliniensis is a fungal opportunistic pathogen originally…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:05

Persistent candida arthritis successfully treated with micafungin instillation and surgery. A case report
Persistent candida arthritis successfully treated with micafungin instillation and surgery. A case report: Publication date: Available online 17 December 2019Source: Medical Mycology Case ReportsAuthor(s): Jeroen C. van Egmond, Nicole G.M. Hunfeld, Bart J.A. Rijnders, Jan A.N. VerhaarAbstractWe report a rare case of C. krusei knee arthritis treated with instillation of micafungin and arthroscopy. A 49-year-old man hospitalized for treatment of Acute Myeloid Leukemia developed knee arthritis with…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:04

Emergent laparoscopic dome resection and omental suturing to the splenic parenchymal edge for a spontaneously ruptured non-parasitic large splenic cyst in a pediatric patient: a case report
Emergent laparoscopic dome resection and omental suturing to the splenic parenchymal edge for a spontaneously ruptured non-parasitic large splenic cyst in a pediatric patient: a case report: AbstractBackgroundSpontaneously ruptured large splenic cyst is a rare in children, and traditionally total or partial splenectomy has been performed for treating an emergent case. We herein present a first case with spontaneously ruptured pediatric splenic cyst treated with emergent laparoscopic dome resection…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:04

A patient with metformin-associated lactic acidosis successfully treated with continuous renal replacement therapy: a case report
A patient with metformin-associated lactic acidosis successfully treated with continuous renal replacement therapy: a case report: Metformin has been widely used as a first-line agent to treat type 2 diabetes mellitus. Lactic acidosis is a rare but serious adverse effect in patients treated with metformin. Recent studies noted a correlati…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:04

Dermatofibrosarcoma protuberans – the use of neoadjuvant imatinib for treatment of an uncommon breast malignancy: a case report
Dermatofibrosarcoma protuberans – the use of neoadjuvant imatinib for treatment of an uncommon breast malignancy: a case report: AbstractBackgroundDermatofibrosarcoma protuberans is a rare soft tissue malignancy that, if left untreated, can be locally destructive and life-threatening. Dermatofibrosarcoma protuberans is uncommon in the breast, and the similarity of its morphologic features with other spindle cell malignancies can make correct identification difficult. Immunohistochemistry and molecular…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:04

Streptococcus constellatus: a rare causative agent of pyogenic liver abscess
Streptococcus constellatus: a rare causative agent of pyogenic liver abscess: A 26-year-old man who was previously well presented to the emergency in septic shock. He had a preceding history of fever, right upper abdominal pain and jaundice. On examination, there was tenderness over the right hypochondrium and epigastrium, without features of generalised peritonitis. His blood tests were suggestive of sepsis with deranged liver function tests. CT scan of the abdomen showed multiples abscesses in…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:03

Mycobacterium bovis prosthetic joint infection following intravesical instillation of BCG for bladder cancer
Mycobacterium bovis prosthetic joint infection following intravesical instillation of BCG for bladder cancer: A 91-year-old man with a history of intravesicular BCG therapy for recurrent bladder cancer and bilateral total hip arthroplasty (THA) presented with left hip pain. He was noted to have a fluid collection over the left lateral hip and hip X-ray showed loosening of the prosthetic hip stem indicative of a prosthetic joint infection (PJI). He subsequently underwent removal of the THA and insertion…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:03

Type 2 diabetes mellitus complicated with idiopathic hypoparathyroidism where poor glycaemic control was associated with low adherence to exercise and medication due to hypocalcaemia
Type 2 diabetes mellitus complicated with idiopathic hypoparathyroidism where poor glycaemic control was associated with low adherence to exercise and medication due to hypocalcaemia: We report a rare case of type 2 diabetes mellitus (T2DM) complicated with idiopathic hypoparathyroidism. A 36-year-old Japanese man was admitted to our hospital owing to poor glycaemic control and hypocalcaemia. The patient had myalgia resulting from hypocalcaemia, which prevented adequate exercise. He considered the…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:03

Elevated GALNT10 expression identifies immunosuppressive microenvironment and dismal prognosis of patients with high grade serous ovarian cancer
Elevated GALNT10 expression identifies immunosuppressive microenvironment and dismal prognosis of patients with high grade serous ovarian cancer: AbstractHigh grade ovarian serous cancer (HGSC) is a malignant disease with high mortality. Glycosylation plays important roles in tumor invasion and immune evasion, but its effect on the immune microenvironment of HGSC remains unclear. This study examined the association of glycosyltransferase expression with HGSC prognosis and explored the underlying…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:03

EBV‐directed viral‐specific T‐lymphocyte therapy for the treatment of EBV‐driven lymphoma in two patients with primary immunodeficiency and DNA repair defects
EBV‐directed viral‐specific T‐lymphocyte therapy for the treatment of EBV‐driven lymphoma in two patients with primary immunodeficiency and DNA repair defects: AbstractChildren with ataxia telangiectasia (AT), a primary immunodeficiency caused by mutations in ATM, which is critical for repairing DNA defects, are at risk for the development of hematologic malignancy, frequently driven by infection with Epstein‐Barr virus (EBV). Conventional chemotherapy is poorly tolerated by patients with AT, with…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:03

Salvage treatment for children with relapsed/refractory germ cell tumors: The Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP) experience
Salvage treatment for children with relapsed/refractory germ cell tumors: The Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP) experience: AbstractBackgroundMalignant germ cell tumors (GCTs) are a heterogeneous group of rare neoplasms in children. Optimal outcome is achieved with multimodal therapies for patients with both localized and advanced disease, especially after the introduction of platinum‐based chemotherapy regimens. In this respect, data on salvage treatment for children…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:02

Donor selection in a pediatric stem cell transplantation cohort using PIRCHE and HLA‐DPB1 typing
Donor selection in a pediatric stem cell transplantation cohort using PIRCHE and HLA‐DPB1 typing: AbstractBackgroundNew strategies to optimize donor selection for hematopoietic stem cell transplantation (HSCT) have mainly been evaluated in adults, but the disease spectrum requiring HSCT differs significantly in children and has consequences for the risk of complications, such as graft‐versus‐host disease (GvHD).ProceduresHere we evaluated whether HLA‐DPB1 and Predicted Indirectly ReCognizable HLA‐Epitope…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:02

Prognostic value of H3K27me3 in children with ependymoma
Prognostic value of H3K27me3 in children with ependymoma: AbstractObjectiveTo investigate the expression of H3K27me3 in different anatomical sites and analyze its prognostic value in children with ependymoma.MethodsA total of 188 children diagnosed with ependymoma were admitted to the Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, between 2012 and 2017, and regular follow‐up was conducted. Expression of H3K27me3 was analyzed by immunohistochemistry and scored semiquantitatively….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:02

Surge of serum interleukin‐2 level in a Japanese patient with cytarabine syndrome
Surge of serum interleukin‐2 level in a Japanese patient with cytarabine syndrome: Cytarabine syndrome is a rare clinical condition characterized by fever, malaise, myalgia, arthralgia, and/or rash that occurs after receipt of cytarabine. Our patient developed fever, malaise, and diffuse body pain shortly following cytarabine initiation despite receiving prophylactic dexamethasone.Feb 19, 2016(PDF) Cytarabine syndrome despite corticosteroid …https://www.researchgate.net › publication › 282468863_Cytarabine_syndro…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:02

Treatment of pediatric high‐grade central nervous system tumors with high‐dose methotrexate in combination with multiagent chemotherapy: A single‐institution experience
Treatment of pediatric high‐grade central nervous system tumors with high‐dose methotrexate in combination with multiagent chemotherapy: A single‐institution experience: AbstractBackgroundEffective treatment for pediatric embryonal brain tumors includes dose‐intensive multiagent chemotherapy (DIMAC) followed by high‐dose chemotherapy with stem cell rescue (HDCSCR). Use of repeated cycles of DIMAC including high‐dose methotrexate (HDMTX) without HDCSCR has not been described.ProcedureWe retrospectively…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:01

Simultaneous osteosarcoma and renal cell carcinoma with BRCA1 mutation in a young male adult with prior oligodendroglioma
Simultaneous osteosarcoma and renal cell carcinoma with BRCA1 mutation in a young male adult with prior oligodendroglioma:

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:01

PD-L1 and MRN synergy in platinum-based chemoresistance of head and neck squamous cell carcinoma
PD-L1 and MRN synergy in platinum-based chemoresistance of head and neck squamous cell carcinoma: British Journal of Cancer, Published online: 19 December 2019; doi:10.1038/s41416-019-0697-xPD-L1 and MRN synergy in platinum-based chemoresistance of head and neck squamous cell carcinomaAbstractBackgroundWe have been investigating the molecular mechanisms of cisplatin-induced chemoresistance in head and neck squamous cell carcinoma (HNSCC). Based on our previous findings, the present study investigates…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 09:00

The Cytosolic DNA-Sensing cGAS-STING Pathway in Cancer [Review]
The Cytosolic DNA-Sensing cGAS-STING Pathway in Cancer [Review]: The recognition of DNA as an immune-stimulatory molecule is an evolutionarily conserved mechanism to initiate rapid innate immune responses against microbial pathogens. The cGAS–STING pathway was discovered as an important DNA-sensing machinery in innate immunity and viral defense. Recent advances have now expanded the roles of cGAS–STING to cancer. Highly aggressive, unstable tumors have evolved to co-opt this program to drive tumorigenic…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 08:59

MRI Tumor Regression Grade and Circulating Tumor DNA as Complementary Tools to Assess Response and Guide Therapy Adaptation in Rectal Cancer
MRI Tumor Regression Grade and Circulating Tumor DNA as Complementary Tools to Assess Response and Guide Therapy Adaptation in Rectal Cancer: Purpose:Response to preoperative chemo-radiotherapy (CRT) varies. We assessed whether circulating tumor DNA (ctDNA) might be an early indicator of tumor response or progression to guide therapy adaptation in rectal cancer.Experimental Design:A total of 243 serial plasma samples were analyzed from 47 patients with localized rectal cancer undergoing CRT. Up to…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 08:59

EGFR amplification induces increased DNA damage response and renders selective sensitivity to Talazoparib (PARP inhibitor) in glioblastoma
EGFR amplification induces increased DNA damage response and renders selective sensitivity to Talazoparib (PARP inhibitor) in glioblastoma: Purpose: Exploration of novel strategies to extend the benefit of PARP inhibitors beyond BRCA-mutant cancers is of great interest in personalized medicine. Here we identified EGFR-amplification as a potential biomarker to predict sensitivity to PARP inhibition, providing selection for GBM patient population who will benefit from PARP inhibition therapy. Experimental…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 08:58

Cell-Free Circulating Tumor DNA Variant Allele Frequency Associates with Survival in Metastatic Cancer
Cell-Free Circulating Tumor DNA Variant Allele Frequency Associates with Survival in Metastatic Cancer: Purpose: Physicians are expected to assess prognosis both for patient counseling and for determining suitability for clinical trials. Increasingly, cell-free circulating tumor DNA (cfDNA) sequencing is being performed for clinical decision-making. We sought to determine whether variant allele frequency (VAF) in cfDNA is associated with prognosis. Experimental Design: We performed a retrospective…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 08:58

5-hydroxymethylcytosine profiles in circulating cell-free DNA associate with disease burden in children with neuroblastoma
5-hydroxymethylcytosine profiles in circulating cell-free DNA associate with disease burden in children with neuroblastoma: Purpose: 5-hydroxymethylcytosine (5-hmC) is an epigenetic marker of open chromatin and active gene expression. We profiled 5-hmC with Nano-hmC-Seal technology using 10ng of plasma derived cell-free DNA (cfDNA) in blood samples from patients with neuroblastoma to determine its utility as a biomarker. Experimental Design: For the Discovery cohort, one hundred 5-hmC profiles were…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 08:58

Agrin in the Muscularis Mucosa Serves as a Biomarker Distinguishing Hyperplastic Polyps from Sessile Serrated Lesions
Agrin in the Muscularis Mucosa Serves as a Biomarker Distinguishing Hyperplastic Polyps from Sessile Serrated Lesions: Purpose: Sessile serrated lesions (SSL) are precursors to colon carcinoma (CRC), and their distinction from other polyps, in particular hyperplastic polyps (HPs), presents significant diagnostic challenges. We evaluated expression patterns in colonic polyps of previously identified CRC-associated extracellular matrix (ECM) proteins to identify markers distinguishing SSLs from other…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 08:58

Intra-articular venous malformation of the knee in children: magnetic resonance imaging findings and significance of synovial involvement
Intra-articular venous malformation of the knee in children: magnetic resonance imaging findings and significance of synovial involvement: AbstractBackgroundIntra-articular venous malformations of the knee are an uncommon cause of unilateral knee pain in children. Timely diagnosis is important because lesions with intrasynovial involvement can lead to joint space hemorrhage and secondary cartilage damage.ObjectiveTo describe our tertiary center’s experience of diagnostics and typical magnetic resonance…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 08:58

Comparison of image quality between synthetic and patients’ electrocardiogram-gated 320-row pediatric cardiac computed tomography
Comparison of image quality between synthetic and patients’ electrocardiogram-gated 320-row pediatric cardiac computed tomography: AbstractBackgroundPediatric cardiac computed tomography (CT) can be acquired without electrode placement by using synthetic electrocardiogram (ECG).ObjectiveTo determine whether the depiction of gross cardiac structures and coronary arteries in 320-row pediatric CT is not inferior when CT is gated with synthetic ECG at 150 beats per minute (bpm), compared to the patients’…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 08:58

Chronic disease self-management programme in socioeconomically vulnerable populations
EFFICHRONIC study protocol: a non-controlled, multicentre European prospective study to measure the efficiency of a chronic disease self-management programme in socioeconomically vulnerable populations: IntroductionMore than 70% of world mortality is due to chronic conditions. Furthermore, it has been proven that social determinants have an enormous impact on both health-related behaviour and on the received attention from healthcare services. These determinants cause health inequalities. The objective…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 08:50

Association between severity of depressive symptoms and chronic knee pain in adults aged over 50 years
Association between severity of depressive symptoms and chronic knee pain in Korean adults aged over 50 years: a cross-sectional study using nationally representative data: ObjectivesTo identify the association between the presence and severity of depressive symptoms and those of chronic knee pain.DesignA retrospective cross-sectional study.ParticipantsWe used data from the sixth Korea National Health and Nutrition Examination Survey (KNHANES VI-2) performed in 2014. Overall, 7550 patients were included…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 08:49

Papingo is a former community in the Ioannina regional unit, Epirus, Greece. Since the 2011 local government reform it has become part of the municipality of Zagori, of which it is a municipal unit. The municipal unit has an area of 34.131 km². It is located in the Vikos–Aoös National Park. Wikipedia Elevation: 958 m Weather: 1°C, Wind N at 2 km/h, 77% Humidity Local time: Thursday 8:41 AM Postal code: 44004 Area code: 26530
Πάπιγκο: Χριστούγεννα στο Πέτρινο ΧωριόΠατήστε εδώ

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Thu Dec 19, 2019 08:41

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com, Telephone consultation 11855 int 1193,

MDPI Journals
PharmaceuticsPharmaceutics, Vol. 11, Pages 687: An Inhalable Theranostic System for Local Tuberculosis Treatment Containing an Isoniazid Loaded Metal Organic Framework Fe-MIL-101-NH2—From Raw MOF to Drug Delivery SystemPharmaceutics, Vol. 11, Pages 687: An Inhalable Theranostic System for Local Tuberculosis Treatment Containing an Isoniazid Loaded Metal Organic Framework Fe-MIL-101-NH2—From Raw MOF to Drug Delivery System Pharmaceutics doi: 10.3390/pharmaceutics11120687 Authors: Gabriela Wyszogrodzka-Gaweł…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:16

MDPI Journals
Microorganisms, Vol. 7, Pages 712: Identification of Insect-Deterrent Metabolites from Acremonium masseei strain CICY026, a Saprophytic Fungus from a Sinkhole in YucatánMicroorganisms, Vol. 7, Pages 712: Identification of Insect-Deterrent Metabolites from Acremonium masseei strain CICY026, a Saprophytic Fungus from a Sinkhole in Yucatán Microorganisms doi: 10.3390/microorganisms7120712 Authors: Ana L. Ruiz-Jiménez Esaú Ruiz-Sánchez Gabriela Heredia Raúl Tapia-Tussell Azucena González-Coloma Karla…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:15

MDPI Journals
International Journal of Environmental Research and Public HealthIJERPH, Vol. 16, Pages 5156: Rainfall Trends and Malaria Occurrences in Limpopo Province, South AfricaIJERPH, Vol. 16, Pages 5156: Rainfall Trends and Malaria Occurrences in Limpopo Province, South Africa International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16245156 Authors: Abiodun Adeola Katlego Ncongwane Gbenga Abiodun Thabo Makgoale Hannes Rautenbach Joel Botai Omolola Adisa Christina Botai This…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:15

MDPI Journals
Cells, Vol. 8, Pages 1658: CD47-SIRPα Signaling Induces Epithelial-Mesenchymal Transition and Cancer Stemness and Links to a Poor Prognosis in Patients with Oral Squamous Cell CarcinomaCells, Vol. 8, Pages 1658: CD47-SIRPα Signaling Induces Epithelial-Mesenchymal Transition and Cancer Stemness and Links to a Poor Prognosis in Patients with Oral Squamous Cell Carcinoma Cells doi: 10.3390/cells8121658 Authors: Pai Bamodu Lin Lin Chu Chien Wang Hsiao Yeh Tsai Background: Oral squamous cell carcinoma…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:14

MDPI Journals
Antibiotics, Vol. 8, Pages 270: The Role of Drug Repurposing in the Development of Novel Antimicrobial Drugs: Non-Antibiotic Pharmacological Agents as Quorum Sensing-InhibitorsAntibiotics, Vol. 8, Pages 270: The Role of Drug Repurposing in the Development of Novel Antimicrobial Drugs: Non-Antibiotic Pharmacological Agents as Quorum Sensing-Inhibitors Antibiotics doi: 10.3390/antibiotics8040270 Authors: Gajdács Spengler Background: The emergence of multidrug-resistant organisms (MDROs) is a global…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:13

Thrombolytic Potential of Novel Thiol-Dependent Fibrinolytic Protease from Bacillus cereus RSA1
Biomolecules, Vol. 10, Pages 3: Thrombolytic Potential of Novel Thiol-Dependent Fibrinolytic Protease from Bacillus cereus RSA1: Biomolecules, Vol. 10, Pages 3: Thrombolytic Potential of Novel Thiol-Dependent Fibrinolytic Protease from Bacillus cereus RSA1Biomolecules doi: 10.3390/biom10010003Authors: Sharma Salem Sharma Gautam Singh The present study demonstrates the production and thrombolytic potential of a novel thermostable thiol-dependent fibrinolytic protease by Bacillus cereus…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:11

High Levels of Glutaminase II Pathway Enzymes in Normal and Cancerous Prostate Suggest a Role in ‘Glutamine Addiction’
Biomolecules, Vol. 10, Pages 2: High Levels of Glutaminase II Pathway Enzymes in Normal and Cancerous Prostate Suggest a Role in ‘Glutamine Addiction’: Biomolecules, Vol. 10, Pages 2: High Levels of Glutaminase II Pathway Enzymes in Normal and Cancerous Prostate Suggest a Role in ‘Glutamine Addiction’Biomolecules doi: 10.3390/biom10010002Authors: Dorai Dorai Pinto Grasso Cooper Abstract: Many tumors readily convert l-glutamine to α-ketoglutarate. This conversion is almost invariably…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:11

Increased Expression of Gankyrin and Stemness Factor Oct-4 are Associated with Unfavorable Clinical Outcomes and Poor Benefit of Tamoxifen in Breast Carcinoma Patients
Increased Expression of Gankyrin and Stemness Factor Oct-4 are Associated with Unfavorable Clinical Outcomes and Poor Benefit of Tamoxifen in Breast Carcinoma Patients: AbstractTamoxifen is the most important treatment component in estrogen receptor positive (ER+) breast carcinoma patients. Tamoxifen resistance incidence presents an important obstacle in clinical treatment. Mechanisms underlying tamoxifen refractory are not completely understood. Although elevated expression of Gankyrin (P28GANK)…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:11

A case of large intra‐esophageal bronchogenic cyst treated with lauromacrogol ablation
A case of large intra‐esophageal bronchogenic cyst treated with lauromacrogol ablation: AbstractA 23‐year‐old man was referred to our hospital because of mild dysphagia to solid food. Computed tomography showed an obvious mass arising from the lower esophagus. In the esophagogastroduodenoscopy examination, a bulging lesion was observed adjacent to the cardia. Endoscopic ultrasound revealed a 4.5×3.8cm hypoechoic cystic lesion without blood flow signal, which affected most of the muscularis propria…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:10

No effect of tDCS of the primary motor cortex on isometric exercise performance or perceived fatigue
No effect of tDCS of the primary motor cortex on isometric exercise performance or perceived fatigue: AbstractAnodal transcranial direct current stimulation (tDCS) of the primary motor cortex has been reported to improve isometric exercise performance without changing corticospinal excitability. One possible cause for this may be the previous use of relatively high (2 mA) current intensities, which have inconsistent effects on corticospinal excitability. The present pre‐registered study aimed to…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:08

Motor Skill Acquisition during a Balance Task as a Process of Optimization of Motor Primitives
Motor Skill Acquisition during a Balance Task as a Process of Optimization of Motor Primitives: AbstractIt has been argued that the central nervous system relies on combining simple movement elements (i.e. motor primitives) to generate complex motor outputs. However, how movement elements are generated and combined during the acquisition of new motor skills is still a source of debate. Herein, we present results providing new insights into the role of movement elements in the acquisition of motor…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:08

Out-of-School Use of Time and Its Association with Gender Differences in Educational Outcomes
Out-of-School Use of Time and Its Association with Gender Differences in Educational Outcomes: AbstractRecent gender literature has highlighted that boys and girls devote their out-of-school time in dissimilar ways, which may differentially influence their academic achievement. Furthermore, this literature indicates that these gender differences may be rooted in society’s gender stereotypes when using this time. To analyse this issue we employ longitudinal and census data for the Spanish region of…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:07

Clinical Applications of 68 Ga-PSMA PET/CT on Residual Disease Assessment of Juvenile Nasopharyngeal Angiofibroma (JNA)
Clinical Applications of 68 Ga-PSMA PET/CT on Residual Disease Assessment of Juvenile Nasopharyngeal Angiofibroma (JNA): AbstractWe present a case of a 16-year-old boy who underwent 68Ga-PSMA PET/CT for residual disease assessment of juvenile nasal angiofibroma. Positive uptake was noted in residual tumor on PET/CT imaging. However, there was no abnormal uptake in surrounding scar tissues as compared with contrast-enhanced magnetic resonance imaging. These findings were confirmed by biopsy from the…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:07

Evaluation of periostin level for predicting severity and chronicity of childhood atopic dermatitis.
Postepy Dermatol Alergol. 2019 Oct;36(5):616-619. doi: 10.5114/ada.2018.79728. Epub 2019 Nov 12.Ozceker D1, Yucel E1, Sipahi S2, Dilek F3, Ozkaya E3, Guler EM4, Kocyigit A4, Guler N2, Tamay Z2.Author information1Department of Pediatric Allergy and Immunology, Okmeydanı Education and Resarch Hospital, Saglik Bilimleri University, Istanbul, Turkey.2Department of Pediatric Allergy and Immunology, Istanbul Medical Faculty, Istanbul, Turkey.3Department of Pediatric Allergy and Immunology, Bezmi Alem University,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:06

Treponema pallidum-specific immune responses and autoimmunity in patients who remain serofast after treatment of syphilis.
Postepy Dermatol Alergol. 2019 Oct;36(5):620-625. doi: 10.5114/ada.2018.77497. Epub 2018 Aug 6.Pastuszczak M1, Kotnis-Gąska A2, Jakubowicz B3, Wojas-Pelc A1.Author information1Department of Dermatology, Jagiellonian University Medical College, Krakow, Poland.2Department of Laboratory Diagnostics, John Paul 2 Hospital, Krakow, Poland.3Department of Microbiology, University Hospital, Krakow, Poland.AbstractINTRODUCTION:Approximately 15% of appropriately treated patients with early syphilis remain serofast….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:06

Elastography reference values of facial skin elasticity.
Postepy Dermatol Alergol. 2019 Oct;36(5):626-634. doi: 10.5114/ada.2018.77502. Epub 2018 Aug 16.Ambroziak M1, Noszczyk B2, Pietruski P2, Guz W3, Paluch Ł4.Author information1Ambroziak Clinic, Warsaw, Poland.2Department of Plastic Surgery, Orlowski Memorial Hospital, Medical Centre of Postgraduate Education, Warsaw, Poland.3Department of Electroradiology, Institute of Nursing and Health Sciences, Faculty of Medicine, University of Rzeszow, Poland.4Department of Radiology, Gruca Orthopedic and Trauma…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:05

Increased Expression of Gankyrin and Stemness Factor Oct-4 are Associated with Unfavorable Clinical Outcomes and Poor Benefit of Tamoxifen in Breast Carcinoma Patients
Increased Expression of Gankyrin and Stemness Factor Oct-4 are Associated with Unfavorable Clinical Outcomes and Poor Benefit of Tamoxifen in Breast Carcinoma Patients: AbstractTamoxifen is the most important treatment component in estrogen receptor positive (ER+) breast carcinoma patients. Tamoxifen resistance incidence presents an important obstacle in clinical treatment. Mechanisms underlying tamoxifen refractory are not completely understood. Although elevated expression of Gankyrin (P28GANK)…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:02

Weight Regain and Diabetes Evolution After Sleeve Gastrectomy
Weight Regain and Diabetes Evolution After Sleeve Gastrectomy: a Cohort Study with over 5 Years of Follow-Up: AbstractBackgroundA number of meta-analyses have demonstrated the effectiveness of bariatric surgery in improving morbid obesity and its associated co-morbidities. The aim of the study was to evaluate at long term a cohort of obese patients with type 2 diabetes (T2DM) submitted to laparoscopic sleeve gastrectomy (LSG) analyzing the incidence of weight regain (WR) and the impact of the WR…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:01

Children with epilepsy demonstrate macro- and microstructural changes in the thalamus, putamen, and amygdala
Children with epilepsy demonstrate macro- and microstructural changes in the thalamus, putamen, and amygdala: AbstractPurposeDespite evidence for macrostructural alteration in epilepsy patients later in life, little is known about the underlying pathological or compensatory mechanisms at younger ages causing these alterations. The aim of this work was to investigate the impact of pediatric epilepsy on the central nervous system, including gray matter volume, cerebral blood flow, and water diffusion,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:01

Hippocampal Volume Loss, Brain Amyloid Accumulation, and APOE Status in Cognitively Intact Elderly Subjects
Hippocampal Volume Loss, Brain Amyloid Accumulation, and APOE Status in Cognitively Intact Elderly Subjects: Background: Hippocampal volume loss (HVL), PET-documented brain amyloid accumulation, and APOE-ε4 status are predictive biomarkers of the transition from mild cognitive impairment to Alzheimer disease (AD). In asymptomatic cases, the role of these biomarkers remains ambiguous. In contrast to the idea that HVL occurs in late phases of neurodegeneration, recent contributions indicate that it…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:01

Analysis of Factors Affecting Quality of Life in Patients Treated for Maxillofacial Fractures
IJERPH, Vol. 17, Pages 4: Analysis of Factors Affecting Quality of Life in Patients Treated for Maxillofacial Fractures: IJERPH, Vol. 17, Pages 4: Analysis of Factors Affecting Quality of Life in Patients Treated for Maxillofacial FracturesInternational Journal of Environmental Research and Public Health doi: 10.3390/ijerph17010004Authors: Sikora Chlubek Grochans Jurczak Safranow Chlubek Maxillofacial fractures (MFF) belong to the major modern medicine and public health concerns….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:00

Internet Gaming Disorder: Exploring Its Impact on Satisfaction in Life in PELLEAS Adolescent Sample
IJERPH, Vol. 17, Pages 3: Internet Gaming Disorder: Exploring Its Impact on Satisfaction in Life in PELLEAS Adolescent Sample: IJERPH, Vol. 17, Pages 3: Internet Gaming Disorder: Exploring Its Impact on Satisfaction in Life in PELLEAS Adolescent SampleInternational Journal of Environmental Research and Public Health doi: 10.3390/ijerph17010003Authors: Olivier Phan Constance Prieur Céline Bonnaire Ivana Obradovic Among adolescents, heavy video game use and socializing online may be valued…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:00

Effects of a probiotic intervention on Escherichia coli and high-fat diet-induced intestinal microbiota imbalance
Effects of a probiotic intervention on Escherichia coli and high-fat diet-induced intestinal microbiota imbalance: AbstractObesity is often associated with intestinal microbiota imbalance and increased Gram-negative bacteria characterized by higher endotoxin levels. Therefore, a study on the joint effects of a high-fat diet and Gram-negative bacteria prechallenge might provide further information on the interactive effects of intestinal microbiota and obesity as well as the effects of a probiotic…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:00

Sulfur-containing amino acid supplementation to gilts from late pregnancy to lactation altered offspring’s intestinal microbiota and plasma metabolites
Sulfur-containing amino acid supplementation to gilts from late pregnancy to lactation altered offspring’s intestinal microbiota and plasma metabolites: AbstractMaternal nutrition during late pregnancy and lactation is highly involved with the offspring’s health status. The study was carried out to evaluate the effects of different ratios of methionine and cysteine (Met/Cys: 46% Met, 51% Met, 56% Met, and 62% Met; maintained with 0.78% of total sulfur-containing amino acids; details in “Materials…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:00

Construction and application of a “superplasmid” for enhanced production of antibiotics
Construction and application of a “superplasmid” for enhanced production of antibiotics: AbstractMore than two-third of known antibiotics are produced by actinomycetes of the genus Streptomyces. Unfortunately, the production rate from Streptomyces natural antibiotic is extremely slow and thus cannot satisfy industrial demand. In this study, the production of antibiotics by Streptomyces is enhanced by a “superplasmid” which including global regulatory factors afsR, cyclic adenosine receptor protein…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:59

Modulation effect of tea consumption on gut microbiota
Modulation effect of tea consumption on gut microbiota: AbstractTea is one of the most popular beverages in the world and possesses a wide range of beneficial effects for human health. The modulation of tea on gut microbiota has gained much interest in recent years. The present study discussed the modulation effect of various types of tea on gut microbiota, which plays crucial roles in human health, as investigated by in vitro animal and human studies. The currently available findings from a total…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:59

Calanus oil in the treatment of obesity-related low-grade inflammation, insulin resistance, and atherosclerosis
Calanus oil in the treatment of obesity-related low-grade inflammation, insulin resistance, and atherosclerosis: AbstractCalanus oil (COil) is a natural product extracted from marine zooplankton Calanus finmarchicus found in the North Atlantic Ocean. This oil is rich in wax esters of polyunsaturated fatty acids (PUFAs) and has been projected as the best alternative to fish oil because its production cannot keep pace with the demands from the growing markets. The COil is the only commercially available…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:59

Inotersen preserves or improves quality of life in hereditary transthyretin amyloidosis
Inotersen preserves or improves quality of life in hereditary transthyretin amyloidosis: AbstractObjectiveTo examine the impact on quality of life (QOL) of patients with hATTR amyloidosis with polyneuropathy treated with inotersen (Tegsedi™) versus placebo.MethodsData were from the NEURO-TTR trial (ClinicalTrials.gov Identifier: NCT01737398), a phase 3, multinational, randomized, double-blind, placebo-controlled study of inotersen in patients with hATTR amyloidosis with polyneuropathy. At baseline…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:58

A Massive Extradural Hematoma in Sickle Cell Disease and the Importance of Rapid Neuroimaging
A Massive Extradural Hematoma in Sickle Cell Disease and the Importance of Rapid Neuroimaging: Sickle cell disease (SCD) is an inherited hemoglobinopathy leading to several serious organ complications and early death. It is mostly found in equatorial countries like Tanzania. Extradural hematoma (EDH) is a rare, but serious complication to SCD and may have debilitating consequences. Hitherto, there is no report of EDH in SCD where neuroimaging has been available before, during, and after such an event….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:58

Subchronic Exposure to Cadmium Causes Persistent Changes in the Reproductive System in Female Wistar Rats
Subchronic Exposure to Cadmium Causes Persistent Changes in the Reproductive System in Female Wistar Rats: Cadmium (Cd) is an environmental toxicant and endocrine disruptor in humans and animals, and recent studies have illustrated that the uterus is exceedingly sensitive to Cd toxicity. The aim of the study was to investigate the influence of subchronic (90 days) oral Cd exposure in daily doses of 0.09-4.5 mg/kg b.w. on the balance of sex hormones by estimating estradiol (E2) and progesterone (P)…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:58

The effect of canal diameter on audiologic results in patients with cochlear implantation with large vestibular aqueduct syndrome
The effect of canal diameter on audiologic results in patients with cochlear implantation with large vestibular aqueduct syndrome: AbstractPurposeTo compare audiologic results according to vestibular aqueduct (VA) diameter in patients who have undergone cochlear implantation and were diagnosed with LVAS.MethodsThis was a retrospective study detailing the outcomes of 18 patients with LVAS and 18 patients undergone cochlear implants. VA diameter was assessed by magnetic resonance imaging and computed…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:57

Bacterial colonization of Montgomery salivary bypass tubes after hypopharyngeal reconstruction in head and neck cancer patients
Bacterial colonization of Montgomery salivary bypass tubes after hypopharyngeal reconstruction in head and neck cancer patients: AbstractBackgroundHypopharyngeal reconstruction after salvage pharyngolaryngectomy results in high postoperative morbidity. The use of salivary bypass tubes can reduce pharyngocutaneous fistula (PCF) formation. The influence of bacterial colonization has not been described in literature.MethodsBacterial swipes from 26 consecutive patients reconstructed after laryngopharyngectomy…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:57

Sample collection for laboratory‐based study of the nasal airway and sinuses: a research compendium
Sample collection for laboratory‐based study of the nasal airway and sinuses: a research compendium: BackgroundCollection of biologic samples from the nasal cavity and paranasal sinuses is of critical importance to the study of infectious or inflammatory conditions that affect both upper and lower airways. Numerous techniques for the study of ex‐vivo samples exist, with specific applications, strengths, and weaknesses associated with each of them. In this compendium we summarize the available methods…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:56

Vascularized lymph node transfer with submental free flap
Vascularized lymph node transfer with submental free flap: Publication date: Available online 16 December 2019Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): P. Mazerolle, T. Meresse, D. Gangloff, K. Kolsi, A. Dupret-BoriesAbstractLimb lymphoedema is common in patients who have undergone inguinal or axillary lymph node dissection. Lymphoedema seriously impacts the patient’s quality of life by inducing adipogenesis, fibrosis and repeated episodes of lymphangitis and…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:56

Optico-carotid recess and anterior clinoid process pneumatization â€" proposal for a novel classiï¬cation and uniï¬ed terminology: an anatomic and radiologic study.
Optico-carotid recess and anterior clinoid process pneumatization â€" proposal for a novel classiï¬cation and uniï¬ed terminology: an anatomic and radiologic study.: Related ArticlesOptico-carotid recess and anterior clinoid process pneumatization â€" proposal for a novel classiï¬cation and uniï¬ed terminology: an anatomic and radiologic study.Rhinology. 2019 Dec 01;57(6):444-450Authors: Andrianakis A, Tomazic PV, Wolf A, Anderhuber F, Gerstenberger C, Pilsl U, Stammberger HAbstract BACKGROUND:…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:56

5-aminolevulinic acid-mediated photodynamic diagnosis using fluorescence ureterorenoscopy for urinary upper tract urothelial carcinoma ∼Preliminary prospective single centre trial∼
5-aminolevulinic acid-mediated photodynamic diagnosis using fluorescence ureterorenoscopy for urinary upper tract urothelial carcinoma ∼Preliminary prospective single centre trial∼: Publication date: Available online 16 December 2019Source: Photodiagnosis and Photodynamic TherapyAuthor(s): Hideo Fukuhara, Atsushi Kurabayashi, Mutsuo Furihata, Shouhei Setuda, Kiwamu Takahashi, Kiyotaka Murakami, Toru Tanaka, Keiji InoueAbstractObjectiveTo investigate the diagnostic accuracy of 5- aminolevulinic acid-mediated…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:55

Mothers’ emotional experiences related to their child’s diagnosis of deafness and cochlear implant surgery: Parenting stress and child’s language development.
Mothers’ emotional experiences related to their child’s diagnosis of deafness and cochlear implant surgery: Parenting stress and child’s language development.: Related ArticlesMothers’ emotional experiences related to their child’s diagnosis of deafness and cochlear implant surgery: Parenting stress and child’s language development.Int J Pediatr Otorhinolaryngol. 2019 Dec 06;130:109812Authors: Majorano M, Guerzoni L, Cuda D, Morelli MAbstract OBJECTIVES: The present study aims to assess the…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:55

Hereditary hearing loss is characterized by a very high genetic heterogeneity. The OTOF gene (Locus: DFNB9), encoding otoferlin, is reported to be one of the major causes of non-syndromic hearing loss, and is also reported to be the most common cause of non-syndromic recessive auditory neuropathy spectrum disorder.
Novel <em>OTOF</em> pathogenic variant segregating with non-syndromic hearing loss in a consanguineous family from tribal Rajouri in Jammu and Kashmir: Publication date: Available online 16 December 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Raja A.H. Kuchay, Yaser Rafiq Mir, Xue Zeng, Asima Hassan, Kazunori Namba, Mustafa TekinAbstractBackgroundHereditary hearing loss is characterized by a very high genetic heterogeneity. The OTOF gene (Locus: DFNB9),…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:55

No Bull: A Case of Alpha-Gal Syndrome Associated With Buffalo Meat Sensitivity.
No Bull: A Case of Alpha-Gal Syndrome Associated With Buffalo Meat Sensitivity.: Related ArticlesNo Bull: A Case of Alpha-Gal Syndrome Associated With Buffalo Meat Sensitivity.Allergy Rhinol (Providence). 2019 Jan-Dec;10:2152656719893366Authors: Rowane M, Valencia R, Stewart-Bates B, Casselman J, Hostoffer RAbstract Introduction: Alpha (⍺)-gal syndrome (AGS) is an immunoglobulin E (IgE) antibody response against the glycoprotein carbohydrate galactose-⍺-1,3-galactose-β-1-(3)4-N-acetylglucosamine-R…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:54

Malignant Chondroid Syringoma With Nose and Paranasal Sinus Extension: A Case Report.
Malignant Chondroid Syringoma With Nose and Paranasal Sinus Extension: A Case Report.: Related ArticlesMalignant Chondroid Syringoma With Nose and Paranasal Sinus Extension: A Case Report.Allergy Rhinol (Providence). 2019 Jan-Dec;10:2152656719893367Authors: Sekar R, Kalaiarasi R, Ganesan S, Alexander A, Saxena SKAbstract Chondroid syringoma is a rare, skin appendageal tumor. It is also known as mixed tumor of skin, as it histologically resembles mixed tumor of salivary gland (pleomorphic…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:53

Complications of bone-conduction hearing implants implantation surgery
Complications of bone-conduction hearing implants implantation surgery: Publication date: Available online 16 December 2019Source: American Journal of OtolaryngologyAuthor(s): Timothy Shun Man Chu, Michael Mather, Anirvan BanerjeeAbstractPurposeBone-conduction Hearing Implants (BCHIs) are surgically implanted hearing devices. As the implantation surgery involves soft tissue dissection through periosteum and drilling of skull, complications related to the skin and soft tissue remain common despite…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:53

Sunscreen: FDA regulation, and environmental and health impact
Sunscreen: FDA regulation, and environmental and health impact: Photochem. Photobiol. Sci., 2020, Advance ArticleDOI: 10.1039/C9PP00366E, PaperShanthi Narla, Henry W. LimDespite the concern for potential environmental and health effects, the FDA still considers organic UVR filters safe for use. For those who are concerned, inorganic UVR filter (namely, zinc oxide and titanium dioxide)-based sunscreens can be used.To cite this article before page numbers are assigned, use the DOI form of citation…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:52

The effect of anatomic variations and maxillary sinus volume in antrochoanal polyp formation
The effect of anatomic variations and maxillary sinus volume in antrochoanal polyp formation: AbstractPurposeThe antrochoanal polyp (ACP), otherwise known as the Killain polyp, is a benign lesion that originates from maxillary sinus mucosa, extending from the accessory ostium towards the middle meatus, and later tends to protrude posteriorly towards the choana and nasopharynx. Many studies have emphasized that its etiopathogenesis is unclear. Research suggests that chronic sinusitis and allergic…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:52

Appropriate medical management of chronic rhinosinusitis reduces use of antibiotics and oral corticosteroids
Appropriate medical management of chronic rhinosinusitis reduces use of antibiotics and oral corticosteroids: Objectives/HypothesisAntibiotics and oral corticosteroids are used in the treatment of acute exacerbations of chronic rhinosinusitis (AECRS) and reflect poor disease control. We sought to characterize utilization of these systemic medications after appropriate medical management of chronic rhinosinusitis (CRS).Study DesignProspective observational study.MethodsOne hundred fifty patients undergoing…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:52

Health utility of rhinectomy, surgical nasal reconstruction, and prosthetic rehabilitation
Health utility of rhinectomy, surgical nasal reconstruction, and prosthetic rehabilitation: ObjectivesAdvanced nasal malignancies may require rhinectomy, which can have profound psychosocial impacts. Rhinectomy defects can be rehabilitated through surgery or prosthetics. We seek to understand the health utility of the rhinectomy defect, surgical, and prosthetic reconstruction, which have not been previously studied.Study DesignProspective clinical studyMethodsAdult naïve observers (n = 273) ranked…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:51

Oxytocin receptor gene loss influences expression of the oxytocin gene in C57BL/6j mice in a sex‐ and age‐dependent manner
Oxytocin receptor gene loss influences expression of the oxytocin gene in C57BL/6j mice in a sex‐ and age‐dependent manner: AbstractParental care and sensory stimulation are critical environmental factors that influence oxytocin (OXT) and its receptor (OXTR). Because developmental Oxt mRNA expression is enhanced by sensory‐rich early life experience, and reduced by sensory deprivation, we predicted that compared to wild‐type (WT) littermates, mice with congenital loss of OXTR (OXTR KO), as a genetically‐induced…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:51

Non-invasive and real-time proliferative activity estimation based on a quantitative radiomics approach for patients with acromegaly: a multicenter study
Non-invasive and real-time proliferative activity estimation based on a quantitative radiomics approach for patients with acromegaly: a multicenter study: AbstractBackgroundProliferative activity prediction is important for determining individual treatment strategies for patients with acromegaly, and tumor proliferative activity is usually measured by the expression of Ki-67.ObjectiveThis study aimed to assess the value of a magnetic resonance imaging (MRI)-based radiomics approach in predicting…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:51

Calcitriol Elevation is Associated with a Higher Risk of Refractory Hypercalcemia of Malignancy in Solid Tumors.
Calcitriol Elevation is Associated with a Higher Risk of Refractory Hypercalcemia of Malignancy in Solid Tumors.: Related ArticlesCalcitriol Elevation is Associated with a Higher Risk of Refractory Hypercalcemia of Malignancy in Solid Tumors.J Clin Endocrinol Metab. 2019 Dec 16;:Authors: Chukir T, Liu Y, Hoffman K, Bilezikian JP, Farooki AAbstract BACKGROUND: Hypercalcemia of malignancy (HCM) is a common complication of advanced cancer. Parathyroid hormone (PTH)-independent HCM may be mediated…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:50

The melanocortin 4 receptor p.Ile269Asn mutation is associated with childhood and adult obesity in Mexicans.
The melanocortin 4 receptor p.Ile269Asn mutation is associated with childhood and adult obesity in Mexicans.: Related ArticlesThe melanocortin 4 receptor p.Ile269Asn mutation is associated with childhood and adult obesity in Mexicans.J Clin Endocrinol Metab. 2019 Dec 16;:Authors: Vázquez-Moreno M, Zeng H, Locia-Morales D, Peralta-Romero J, Asif H, Maharaj A, Tam V, Romero-Figueroa MDS, Sosa-Bustamante GP, Méndez-Martínez S, Mejía-Benítez A, Valladares-Salgado A, Wacher-Rodarte N, National Obesity…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:50

Clinicopathologic overlap of psoriasis, eczema, and psoriasiform dermatoses: A retrospective study of T helper type 2 and 17 subsets, interleukin 36, and β-defensin 2 in spongiotic psoriasiform dermatitis, sebopsoriasis, and tumor necrosis factor α inhibitor–associated dermatitis
Clinicopathologic overlap of psoriasis, eczema, and psoriasiform dermatoses: A retrospective study of T helper type 2 and 17 subsets, interleukin 36, and β-defensin 2 in spongiotic psoriasiform dermatitis, sebopsoriasis, and tumor necrosis factor α inhibitor–associated dermatitis: Publication date: Available online 16 December 2019Source: Journal of the American Academy of DermatologyAuthor(s): Jarish N. Cohen, Sarah Bowman, Zoltan G. Laszik, Jeffrey P. NorthBackgroundT helper (Th) type 17 and Th2…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:47

Serial biologic therapies in psoriasis patients: A 12-year, single-center, retrospective observational study
Serial biologic therapies in psoriasis patients: A 12-year, single-center, retrospective observational study: Publication date: January 2020Source: Journal of the American Academy of Dermatology, Volume 82, Issue 1Author(s): Emanuele Cozzani, Yiran Wei, Martina Burlando, Alessio Signori, Aurora ParodiBackgroundBiologic therapy for psoriasis is effective but not always long-lasting and sometimes needs to be switched.ObjectiveWe aimed to evaluate the drug survival (ie, the time from initiation to discontinuation)…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:46

Exploring changes in placebo treatment arms in hidradenitis suppurativa randomized clinical trials: A systematic review
Exploring changes in placebo treatment arms in hidradenitis suppurativa randomized clinical trials: A systematic review: Publication date: January 2020Source: Journal of the American Academy of Dermatology, Volume 82, Issue 1Author(s): Asma Amir Ali, Elizabeth K. Seng, Afsaneh Alavi, Michelle A. LowesBackgroundHidradenitis suppurativa (HS) is characterized by recurrent, painful nodules in flexural areas.ObjectiveThe objective of this study was to explore the placebo response in HS randomized clinical…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:46

Measuring psoriatic arthritis symptoms: A core domain in psoriasis clinical trials
Measuring psoriatic arthritis symptoms: A core domain in psoriasis clinical trials: Publication date: January 2020Source: Journal of the American Academy of Dermatology, Volume 82, Issue 1Author(s): Lourdes Maria Perez-Chada, Alice Bendix Gottlieb, Jeffrey Cohen, Philip Mease, Kristina Callis Duffin, Amit Garg, John Latella, April Wang Armstrong, Alexis Ogdie, Joseph Frank MerolaBackgroundThe International Dermatology Outcome Measures established a set of core domains to be measured in all psoriasis…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:46

Topical cholesterol/lovastatin for the treatment of porokeratosis: A pathogenesis-directed therapy
Topical cholesterol/lovastatin for the treatment of porokeratosis: A pathogenesis-directed therapy: Publication date: January 2020Source: Journal of the American Academy of Dermatology, Volume 82, Issue 1Author(s): Lihi Atzmony, Young H. Lim, Claire Hamilton, Jonathan S. Leventhal, Annette Wagner, Amy S. Paller, Keith A. ChoateBackgroundPorokeratosis is associated with mevalonate pathway gene mutations. Therapeutic options are few and often limited in efficacy. We hypothesized that topical therapy…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:45

The impact of dupilumab on patch testing and the prevalence of comorbid allergic contact dermatitis in recalcitrant atopic dermatitis: A retrospective chart review
The impact of dupilumab on patch testing and the prevalence of comorbid allergic contact dermatitis in recalcitrant atopic dermatitis: A retrospective chart review: Publication date: January 2020Source: Journal of the American Academy of Dermatology, Volume 82, Issue 1Author(s): Jodie Raffi, Raagini Suresh, Nina Botto, Jenny E. MuraseBackgroundIt is unclear whether the type 2 T helper cell–specific immunosuppressive action of dupilumab interferes with patch testing.ObjectivesWe sought to evaluate…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:45

Improved overall survival of melanoma of the head and neck treated with Mohs micrographic surgery versus wide local excision
Improved overall survival of melanoma of the head and neck treated with Mohs micrographic surgery versus wide local excision: Publication date: January 2020Source: Journal of the American Academy of Dermatology, Volume 82, Issue 1Author(s): Jamie Hanson, Addison Demer, Walter Liszewski, Neal Foman, Ian MaherBackgroundOptimal surgical management for melanoma of the head and neck remains controversial.ObjectiveAssess outcomes for melanomas of the head and neck treated with Mohs micrographic surgery…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:45

Histopathologic features that distinguish secondary syphilis from pityriasis lichenoides (PL), pityriasis rosea (PR), and early mycosis fungoides (MF).
Histopathologic features distinguishing secondary syphilis from its mimickers: Publication date: January 2020Source: Journal of the American Academy of Dermatology, Volume 82, Issue 1Author(s): Alexandra Flamm, Veronica Merelo Alcocer, Viktoryia Kazlouskaya, Eun Ji Kwon, Dirk ElstonBackgroundSyphilis is often misdiagnosed clinically, and biopsies might be required.ObjectiveTo determine histopathologic features that distinguish secondary syphilis from pityriasis lichenoides (PL), pityriasis rosea…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:44

Management of pediatric plaque psoriasis using biologics
Management of pediatric plaque psoriasis using biologics: Publication date: January 2020Source: Journal of the American Academy of Dermatology, Volume 82, Issue 1Author(s): Perla Lansang, James N. Bergman, Loretta Fiorillo, Marissa Joseph, Irene Lara-Corrales, Danielle Marcoux, Catherine McCuaig, Elena Pope, Vimal H. Prajapati, Sue Z.J. Li, Ian LandellsBackgroundPsoriasis is a chronic inflammatory disease with clinical manifestations of the skin that affect adults and children. In adults, biologics…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:43

The emerging utility of the cutaneous microbiome in the treatment of acne and atopic dermatitis
The emerging utility of the cutaneous microbiome in the treatment of acne and atopic dermatitis: Publication date: January 2020Source: Journal of the American Academy of Dermatology, Volume 82, Issue 1Author(s): Taylor E. Woo, Christopher D. SibleyThe cutaneous microbiome has potential for therapeutic intervention in inflammatory-driven skin disease. Research into atopic dermatitis and acne vulgaris has highlighted the importance of the skin microbiota in disease pathogenesis, prognostication, and…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:43

Lactobacillus Endocarditis-Associated Glomerulonephritis Complicated by anti-Coagulant Nephropathy and Renal Amyloidosis
Lactobacillus Endocarditis-Associated Glomerulonephritis Complicated by anti-Coagulant Nephropathy and Renal Amyloidosis: Kidney injury is a well-known sequelae of infectious endocarditis. Various types of kidney injury can be seen, including endocarditis-associated glomerulonephritis, and may affect nearly half of the patients with infectious endocarditis. Lactobacillus species are an infrequently documented cause of endocarditis. We present a case of Lactobacillus endocarditis-associated glomerulonephritis…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:41

Labial Adhesions Causing Recurrent Urinary-Tract Infections in an Elderly Woman
Labial Adhesions Causing Recurrent Urinary-Tract Infections in an Elderly Woman: A 91-year-old postmenopausal woman with a prior history of two labial-adhesion separations suffered from recurrent urinary-tract infections. We were able to successfully treat her labial adhesions using surgery.

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:41

Optic Nerve Hypoplasia, Corpus Callosum Agenesis, Cataract, and Lissencephaly in a Neonate with a Novel COL4A1 Mutation
Optic Nerve Hypoplasia, Corpus Callosum Agenesis, Cataract, and Lissencephaly in a Neonate with a Novel <b><i>COL4A1</i></b> Mutation: We report the case of a girl with a novel mutation of the COL4A gene (c.2716+2T#x3e;C) presenting microcephaly, parenchymal hemorrhages, lissencephaly, and bilateral cataracts, associated with agenesis of the corpus callosum and hypoplasia of the optic nerve. COL4A1, located on chromosome 13, encodes the α1 chain of type IV collagen, a key…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:40

Double-Needle Yamane Repositioning of a Previous Yamane Fixation
Double-Needle Yamane Repositioning of a Previous Yamane Fixation: We describe a case of anteriorly dislocated, Yamane-fixated secondary intraocular lens (IOLs) with pigmentary dispersion syndrome. The patient presented with significant visual impairment and elevated intraocular pressure despite being maximally treated with all topical antihypertensive medications. The iris-IOL touch was confirmed by ultrasound biomicroscopy, and fundus examination revealed evidence of pigment granules on the optic…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:39

Penile reconstruction using scrotal flap after usage of monopolar electrocautery in a 2-month-old Syrian child: a case report
Penile reconstruction using scrotal flap after usage of monopolar electrocautery in a 2-month-old Syrian child: a case report: AbstractCircumcision is regarded as one of the most common procedures in pediatrics. We present a case of a newborn, who has undergone circumcision using monopolar electrocautery. He admitted to the hospital with glans necrosis and was treated with antibiotics and surgical debridement. Four months later, phalloplasty was performed for the newborn using scrotal flap. The result…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:38

Mechanical intestinal obstruction following laparoscopic inguinal hernia repair in a patient with abdominal cocoon syndrome
Mechanical intestinal obstruction following laparoscopic inguinal hernia repair in a patient with abdominal cocoon syndrome: AbstractAbdominal cocoon syndrome (ACS) is a rare condition characterized by partial or complete encasement of small intestine by a thick fibro-collagenous membrane. A 65-year-old man presented to the surgical department with left inguinal. He underwent laparoscopic transabdominal preperitoneal inguinal hernia. When we inserted a trocar into the peritoneal cavity, the small…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:38

Pararectal angiomyxoma: a diagnostic dilemma
Pararectal angiomyxoma: a diagnostic dilemma: AbstractClinical diagnosis of pararectal masses remains a challenge to this day. Despite the availability of advanced imaging facilities, we often fail to reach a definitive diagnosis and have to resort to surgery. We describe a case of a 60-year-old female with a painless perianal swelling gradually increasing in size for 6 months with spontaneous reduction on assuming a supine position. Clinical examination of this patient was suggestive of a pelvic…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:38

A case of sigmoid colon perforation presenting with pneumomediastinum
A case of sigmoid colon perforation presenting with pneumomediastinum: AbstractA 62-year-old woman had developed polymyositis 12 years previously and had taken oral steroids. Chest and abdominal computed tomography showed pneumomediastinum and free air in the abdominal cavity. Although a colon perforation was suspected, the perforation site could not be identified on the image. In addition, a diagnosis of oesophageal rupture could not be excluded from the findings of pneumomediastinum. After general…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:38

Pancreatic solid serous cystadenoma: a rare entity that can lead to a futile surgery
Pancreatic solid serous cystadenoma: a rare entity that can lead to a futile surgery: AbstractAlthough many types of pancreatic tumors exist, pancreatic solid serous cystadenoma stand as the most rare. Despite advances in medical imaging, definitive diagnosis remains complex. Here, we report a case of a 63-year-old man with a suspicious lesion of the pancreas discovered during a positron emission tomography–computed tomography. Despite an echo-endoscopy being performed, no biopsies were contributive….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:37

Septo-optic dysplasia with amniotic band syndrome sequence: a case report
Septo-optic dysplasia with amniotic band syndrome sequence: a case report: Insiyah A. Amiji, Ummulkheir H. Mohamed, Adelina G. Rutashobya, Mariam Mngoya, Nicole Schoenmann, Helga E. Naburi & Karim P. Manji Journal of Medical Case Reports volume 13, Article number: 370 (2019) Cite this article48 Accesses1 AltmetricMetricsdetailsAbstractIntroductionDe Morsier syndrome, or septo-optic dysplasia, is a rare, heterogeneous, complex condition with a highly variable phenotype. It is characterized by…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:36

Continuous intravenous low-dose diclofenac sodium to control a central fever after ischemic stroke in the intensive care unit: a case report and review of the literature
Continuous intravenous low-dose diclofenac sodium to control a central fever after ischemic stroke in the intensive care unit: a case report and review of the literature: AbstractIntroductionElevation in body temperature within the first 24 hours of ischemic stroke is fairly common and known to be associated with worse outcomes. Only after thoroughly ruling out infection and the noninfectious etiologies and in the appropriate clinical setting should the diagnosis of central fever be made. Acetaminophen…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:35

Pneumothorax associated with giant bullous emphysema and mediastinum deviation
Pneumothorax associated with giant bullous emphysema and mediastinum deviation:

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:34

Successful emergency management of a bleeding tracheoinnominate fistula
Successful emergency management of a bleeding tracheoinnominate fistula: In this case, we describe a novel approach to achieving temporary haemostasis in acute massive haemorrhage from a bleeding tracheoinnominate fistula. We report the case of a 42-year-old man admitted to hospital after suffering 80% body surface area burns. Thirty days following the percutaneous insertion of a tracheostomy, spontaneous massive haemorrhage occurred via the tracheostomy stoma, the tracheostomy tube and the mouth….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:33

Oral focal mucinosis of the mandible in an adolescent patient
Oral focal mucinosis of the mandible in an adolescent patient: Oral focal mucinosis (OFM) is the rare oral manifestation of cutaneous focal mucinosis. It is a diagnosis made histopathologically, as OFM remains clinically similar to other more common oral lesions, and radiographs do not provide any diagnostic information. This case is a report of a teenage female with left mandibular involvement of an elevated, rounded, asymptomatic, mucosa-coloured lesion in the facial and lingual gingiva between…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:31

Impact of radiological diagnostics in the survivor of disseminated Fournier gangrene patient with septic pulmonary embolism
Impact of radiological diagnostics in the survivor of disseminated Fournier gangrene patient with septic pulmonary embolism: A 51-year-old diabetic man diagnosed with prostatic abscess underwent its drainage twice. Following surgery he developed fever and right-sided painless visual loss due to endophthalmitis. To rule out its endogenous source CT scan was done which showed multisystem aetiology and complications. His pelvic CT and CT cystogram revealed postsurgical urethral injury along with urinary…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:31

Use of home telemedicine for critical illness rehabilitation: an Indian success story.
Use of home telemedicine for critical illness rehabilitation: an Indian success story.: Unnikrishnan et al. Present a case report of a 26 year old male with Duchenne Muscular Dystrophy who benefited from the use of Telemedicine in the setting post-ICU rehabilitation. The Who defines Telemedicine as follows: “the delivery of healthcare services, where distance is a critical factor, by all healthcare professionals using information and communication technologies for the exchange of valid information…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:31

Acute Intake of a Grape and Blueberry Polyphenol-Rich Extract Ameliorates Cognitive Performance in Healthy Young Adults During a Sustained Cognitive Effort
Antioxidants, Vol. 8, Pages 650: Acute Intake of a Grape and Blueberry Polyphenol-Rich Extract Ameliorates Cognitive Performance in Healthy Young Adults During a Sustained Cognitive Effort: Antioxidants, Vol. 8, Pages 650: Acute Intake of a Grape and Blueberry Polyphenol-Rich Extract Ameliorates Cognitive Performance in Healthy Young Adults During a Sustained Cognitive EffortAntioxidants doi: 10.3390/antiox8120650Authors: Pierre Philip Patricia Sagaspe Jacques Taillard Claire Mandon Joël…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:31

Elevated activity levels do not influence extrinsic fiber attachment morphology on the surface of muscle‐attachment sites
Elevated activity levels do not influence extrinsic fiber attachment morphology on the surface of muscle‐attachment sites: This study adapts surface metrological techniques to the automated, quantitative and non‐destructive analysis of bone surface histology. Although extrinsic fiber (EF) presence does indicate muscle attachment, activity does not have an observable effect on EF morphology.AbstractExtrinsic fibers (EFs) are a type of penetrating collagenous fiber, closely related to the periodontal…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:30

Developmental studies on the acquisition of perception conducting pathways via TRP channels in rat molar odontoblasts using immunohistochemistry and RT-qPCR
Developmental studies on the acquisition of perception conducting pathways via TRP channels in rat molar odontoblasts using immunohistochemistry and RT-qPCR: AbstractOdontoblasts act as dentin formation and sensory receptors. Recently, it was reported that transient receptor potential ankyrin (TRPA) 1, TRP vanilloid (TRPV) 4 and pannexin 1 (PANX-1) play important roles in odontoblast sensory reception. However, it is not known when odontoblasts begin to possess a sense reception function. The aim…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:30

The impact of cirrhosis in patients undergoing cardiac surgery: a retrospective observational cohort study
The impact of cirrhosis in patients undergoing cardiac surgery: a retrospective observational cohort study: AbstractPurposePatients with cirrhosis and concomitant coronary/valvular heart disease present a clinical dilemma. The therapeutic outcome of major cardiac surgery is significantly poorer in patients with cirrhosis compared with patients without cirrhosis. To address this, we aimed to identify associations between the severity of cirrhosis and post-cardiac surgical outcomes.MethodsA historical…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:20

Knowledge and perceptions about perioperative stroke: a cross-sectional survey of patients scheduled for non-neurologic and non-cardiac surgery
Knowledge and perceptions about perioperative stroke: a cross-sectional survey of patients scheduled for non-neurologic and non-cardiac surgery: AbstractPurposePerioperative stroke is associated with significant morbidity and mortality yet patients may not be aware of their risk or receive appropriate counselling. Our objectives were to 1) compare patient’s perceived vs calculated risk of stroke; 2) determine level of worry; and 3) assess prior discussion about perioperative stroke risk amongst elective…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:20

Risk factors for reintubation after anterior cervical discectomy and fusion surgery: evaluation of three observational data sets
Risk factors for reintubation after anterior cervical discectomy and fusion surgery: evaluation of three observational data sets: AbstractPurposePostoperative loss of airway requiring reintubation is a rare but potentially catastrophic complication following anterior cervical discectomy and fusion (ACDF). We sought to identify risk factors asscociated with reintubation within one day following ACDF. Attention was focused on patient demographics, comorbidities, and factors potentially linked to soft…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:20

Managing and securing the bleeding upper airway: a narrative review
Managing and securing the bleeding upper airway: a narrative review: AbstractFailure to manage bleeding in the airway is an important cause of airway-related death. The purpose of this narrative review is to identify techniques and strategies that can be employed when severe bleeding in the upper airway may render traditional airway management (e.g., facemask ventilation, intubation via direct/video laryngoscopy, flexible bronchoscopy) impossible because of impeded vision. An extensive literature…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:19

Rate, Rhythm, and Risk: Perioperative Atrial Fibrillation
Rate, Rhythm, and Risk: Perioperative New-Onset Atrial Fibrillation: FEATURED ARTICLESAtrial Fibrillation: Current Evidence and Management Strategies During the Perioperative PeriodKaramchandani, Kunal MD, FCCP*; Khanna, Ashish K. MD, FCCP, FCCM†,‡; Bose, Somnath MD§; Fernando, Rohesh J. MD, FASE‖; Walkey, Allan J. MD, MSc¶,#Author InformationFrom the *Department of Anesthesiology & Perioperative Medicine, Penn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania†Department of…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:08

Atrial Fibrillation: Current Evidence and Management Strategies During the Perioperative Period
Atrial Fibrillation: Current Evidence and Management Strategies During the Perioperative Period: Atrial fibrillation (AF) is the most common arrhythmia in the perioperative period. Previously considered a benign and self-limited entity, recent data suggest that perioperative AF is associated with considerable morbidity and mortality and may predict long-term AF and stroke risk in some patients. Despite known risk factors, AF remains largely unpredictable, especially after noncardiac surgery. As a…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:04

Comparison of general anesthesia with endotracheal intubation, combined spinal-epidural anesthesia, and general anesthesia with laryngeal mask airway and nerve block for intertrochanteric fracture surgeries in elderly patients: a retrospective cohort study
Comparison of general anesthesia with endotracheal intubation, combined spinal-epidural anesthesia, and general anesthesia with laryngeal mask airway and nerve block for intertrochanteric fracture surgeries in elderly patients: a retrospective cohort study: AbstractBackgroundThere is no consensus on the optimal anesthesia method for intertrochanteric fracture surgeries in elderly patients. Our study aimed to compare the hemodynamics and perioperative outcomes of general anesthesia with endotracheal…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:04

Anxiety and food allergy
Anxiety and food allergy: AbstractBackgroundFood allergy (FA) is recognized as a growing public health burden affecting 5 to 10% of children worldwide. Several unique features specific to FA elicit high levels of emotional distress and anxiety in patients and caregivers, the first among all the possibility of a life‐threatening reaction. Anxiety disorders are highly prevalent in patients with chronic disease, but remain undertreated despite significant negative consequences on patient health.ObjectiveThis…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:03

Modulation of allergic inflammation in the lung by a peptide derived from mycobacteria tuberculosis chaperonin 60.1
Modulation of allergic inflammation in the lung by a peptide derived from mycobacteria tuberculosis chaperonin 60.1: AbstractBackgroundWe have previously demonstrated that M. tuberculosis chaperonin 60.1 inhibits leukocyte diapedesis and bronchial hyperresponsiveness in a murine model of allergic lung inflammation.MethodsIn the present study we have investigated the effect of a shorter peptide sequence derived from Cpn 60.1, named IRL201104, on allergic lung inflammation induced by ovalbumin (OVA)…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:02

Maternal psychological distress before birth influences gut immunity in mid‐infancy
Maternal psychological distress before birth influences gut immunity in mid‐infancy: AbstractBackgroundMaternal pre‐postnatal psychosocial distress increases the risk for childhood allergic disease. This may occur through a host immunity pathway that involves intestinal secretory Immuno‐globulin A (sIgA). Experimental animal models show changes in the gut microbiome and immunity of offspring when exposed to direct or prenatal maternal stress, but little is known in humans.ObjectiveWe determined the…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:02

Late-onset interstitial nephritis in a patient with drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms.
Late-onset interstitial nephritis in a patient with drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms.: Related ArticlesLate-onset interstitial nephritis in a patient with drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms.J Dermatol. 2019 Dec 16;:Authors: Higashi Y, Baba N, Yoshimine H, Sakaguchi I, Kanekura TAbstract Drug-induced hypersensitivity syndrome (DIHS), also referred to as drug reaction with eosinophilia…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:02

Non-canonical autophagy in dermal dendritic cells mediates immunosuppressive effects of UV exposure
Non-canonical autophagy in dermal dendritic cells mediates immunosuppressive effects of UV exposure: Publication date: Available online 16 December 2019Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Payel Sil, Jutamas Suwanpradid, Ginger Muse, Artiom Gruzdev, Liwen Liu, David L. Corcoran, Cynthia J. Willson, Kyathanahalli Janardhan, Sara Grimm, Page Myers, Laura Miller Degraff, Amanda S. MacLeod, Jennifer MartinezAbstractBackgroundControl of the inflammatory response is critical to…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:02

Comparative study of food allergies in children
Comparative study of food allergies in children from China, India and Russia: The EuroPrevall-INCO surveys: Publication date: Available online 16 December 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Jing Li, Ludmila M. Ogorodova, Padukudru Anand Mahesh, Maggie Haitian Wang, Olga Sergeevna Fedorova, Ting Fan Leung, Montserrat Fernandez-Rivas, EN Clare Mills, James Potts, Ischa Kummeling, Serge A. Versteeg, Ronald van Ree, Maria Yazdanbakhsh, Peter GJ. Burney,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:01

Long-term combinations and updosing of second-generation H1-antihistamines show efficacy and safety in the treatment of chronic spontaneous urticaria: a multi-center real-life pilot study
Long-term combinations and updosing of second-generation H₁-antihistamines show efficacy and safety in the treatment of chronic spontaneous urticaria: a multi-center real-life pilot study: Publication date: Available online 16 December 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Liming Zhang, Jian Wu, Yumeng Qi, Hong Zhu, Xu Yao, Mengmeng Li, Jingyi Li, Zaipei Guo, Xiangyang Su, Wei Lai, Siyu Hao, Yuzhen Li, Yang Li, Chunli Yao, Fuqiu Li,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:01

Structural non-infectious manifestations of the central nervous system in common variable immunodeficiency disorders
Structural non-infectious manifestations of the central nervous system in common variable immunodeficiency disorders: Publication date: Available online 16 December 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Annick van de Ven, Irina Mader, Daniel Wolff, Sigune Goldacker, Hannah Fuhrer, Sebastian Rauer, Bodo Grimbacher, Klaus WarnatzAbstractBackgroundCentral nervous system (CNS) disease in adult common variable immunodeficiency (CVID) is rare and therefore diagnostic…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

07:58

Natural Language Processing Combined with ICD-9-CM Codes as a Novel Method to Study the Epidemiology of Allergic Drug Reactions
Natural Language Processing Combined with ICD-9-CM Codes as a Novel Method to Study the Epidemiology of Allergic Drug Reactions: Publication date: Available online 16 December 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Aleena Banerji, Kenneth H. Lai, Yu Li, Rebecca R. Saff, Carlos A. Camargo, Kimberly G. Blumenthal, Li ZhouAbstractBackgroundAllergic drug reaction epidemiologic data are sparse because it remains difficult to identify true cases in large datasets…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

07:58

Trajectory analyses of adherence patterns in a real-life moderate to severe asthma population
Trajectory analyses of adherence patterns in a real-life moderate to severe asthma population: Publication date: Available online 16 December 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Job FM. van Boven, Marjaana Koponen, Samanta Lalic, Johnson George, J. Simon Bell, Mark Hew, Jenni IlomakiAbstractBackgroundGlobal Initiative for Asthma step 5 therapies (GINA-5), other than inhaled corticosteroids and long-acting beta agonists in fixed dose combinations (ICS/LABA…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

07:58

CARsomes inhibit airway allergic inflammation in mice by inducing antigen specific Th2 cell apoptosis
CARsomes inhibit airway allergic inflammation in mice by inducing antigen specific Th2 cell apoptosis: AbstractBackgroundSkewed T helper (Th)2 response plays a crucial role in the pathogenesis of allergic diseases. The therapeutic efficacy for allergic diseases is unsatisfactory currently. This study aims to regulate the skewed Th2 response with CARsomes.MethodsThe CARsome consisted of an epitope of Dermatophagoides farina‐1 (Derf1), a segment of the anti‐DEC205 antibody, the scFv, and an open reading…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

07:57

Clinical utility of the Quantra® point‐of‐care haemostasis analyser during urgent cardiac surgery
Clinical utility of the Quantra® point‐of‐care haemostasis analyser during urgent cardiac surgery: SummaryCoagulopathic bleeding during and after cardiac surgery is associated with increased morbidity and mortality. Viscoelastic testing is increasingly used instead of laboratory testing. Our aim was to compare a new viscoelastic point‐of‐care device, the Quantra® System, with thromboelastography and standard laboratory testing. After ethical approval and with written informed consent, we prospectively…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

07:56

Immediate Plastic Surgery Closure at Index Spinal Surgery Minimizes Complications Compared to Delayed Reconstruction: A Retrospective Cohort Review
Immediate Plastic Surgery Closure at Index Spinal Surgery Minimizes Complications Compared to Delayed Reconstruction: A Retrospective Cohort Review: Complex spine surgery in patients with major comorbidities leads to increased need for midline back wound reconstruction by plastic surgeons. Literature suggests back wound reconstruction concurrent with high-risk immediate/index spine surgery may lead to fewer complication. This study aimed to validate this claim in a large cohort treated at a tertiary…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

07:56

Increasing Abdominal Wall Thickness Predicts Complications in Abdominally-Based Breast Reconstruction: A Review of 106 Consecutive Patients
Increasing Abdominal Wall Thickness Predicts Complications in Abdominally-Based Breast Reconstruction: A Review of 106 Consecutive Patients: Body mass index (BMI) has long been the proxy for patient selection in obese patients presenting for abdominally based breast reconstruction. Body mass index, however, fails to accurately reflect the distribution of abdominal adipose tissue. This study aims to quantify the effect of abdominal wall thickness on the incidence of post-operative complications and…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

07:56

Biportal Transparotid Dissection in the Retromandibular Approach for Condylar Fracture Osteosynthesis: Efficacy of a Novel Technique
Biportal Transparotid Dissection in the Retromandibular Approach for Condylar Fracture Osteosynthesis: Efficacy of a Novel Technique: : Facial nerve injury is a primary complication of open surgical management of condylar fractures. A new modification of the retromandibular transparotid approach, the “biportal transparotid dissection” (BTD), was developed to reduce these injuries in accidental nerve exposure.AbstractObjective: Facial nerve injury is a primary complication of open surgical management…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

07:56

The effect of intrathecal bupivacaine/morphine on quality of recovery in robot‐assisted radical prostatectomy: a randomised controlled trial
The effect of intrathecal bupivacaine/morphine on quality of recovery in robot‐assisted radical prostatectomy: a randomised controlled trial: SummaryRobot‐assisted radical prostatectomy causes discomfort in the immediate postoperative period. This randomised controlled trial investigated if intrathecal bupivacaine/morphine, in addition to general anaesthesia, could be beneficial for the postoperative quality of recovery. One hundred and fifty‐five patients were randomly allocated to an intervention…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

07:55

2′-Hydroxychalcones as an alternative treatment for trichomoniasis in association with metronidazole
2′-Hydroxychalcones as an alternative treatment for trichomoniasis in association with metronidazole: AbstractThe treatment for trichomoniasis, based on 5′-nitroimidazol agents, has been presenting failures related to allergic reactions, side effects, and the emergence of resistant isolates. There are no alternative drugs approved for the treatment of these cases; thus, the search for new active molecules is necessary. In this scenario, chalcones have been extensively studied for their promising…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

07:54

Different prognostic significance of examined lymph node count for patients with non-small-cell lung cancer ≤1 cm or >1–2 cm: a population-based study
Different prognostic significance of examined lymph node count for patients with non-small-cell lung cancer ≤1 cm or >1–2 cm: a population-based study: Future Oncology, Ahead of Print. Aim: This study aimed to investigate the impact of examined lymph node (ELN) count on survival of resected pT1a-1bN0M0 non-small-cell lung cancer (NSCLC). Materials & methods: Data were extracted from the US Surveillance, Epidemiology and End Results database. The association between ELN count and overall survival…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

07:54

Severe hyperandrogenism due to ovarian hyperthecosis in a young woman
Severe hyperandrogenism due to ovarian hyperthecosis in a young woman: Hyperandrogenism is a relatively common clinical problem. However, severe hyperandrogenism causing virilisation is rare. A 27-year-old woman presented with generalised hirsutism, clitoromegaly, breast atrophy and secondary amenorrhoea. She had serum testosterone levels elevated to the adult male range. Administration of gonadotropin-releasing hormone (GnRH) analogue resulted in >50% suppression of serum testosterone which was…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

07:51

Late ventricular standstill following an elective Transcatheter aortic valve implantations (TAVIs)
Late ventricular standstill following an elective TAVI: Transcatheter aortic valve implantations (TAVIs) may be complicated by a need for permanent pacemaker implantation post procedure, usually due to local trauma or compression on the conduction system. There are some features that might help predict that a patient is high risk for developing conduction disease following TAVI, for example, underlying right bundle branch block or use of certain types of TAVI. It might also become apparent during…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

07:51

Isolated CNS leukaemic relapse in acute myeloid leukaemia
Isolated CNS leukaemic relapse in acute myeloid leukaemia: DescriptionA 61-year-old woman with acute myeloid leukaemia (AML) without maturation (M1) with trisomy 13 who achieved complete remission after her initial diagnosis with cytarabine and idarubicin. Two years later, she relapsed and underwent successful haematopoietic stem cell transplantation afterwards, and she entered complete remission. Sixteen months later, she presented to our emergency department with a 2-week history of worsening fatigue,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

07:49

Primary seminal vesicle adenocarcinoma
Primary seminal vesicle adenocarcinoma: a lethal yet cryptic malignancy with review of literature: The rarity of primary seminal vesical adenocarcinoma (PSVA) coupled with mostly late and advanced presentation with high mortality makes it an unanticipated malignancy with poor prognosis. Although there has been sporadic reporting of cases, the dearth of literature makes standardised care a challenge. The detection has incorporated immunohistochemistry for establishing the site of origin as well as…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

07:47

Somatosensory changes in patients after coronectomy vs. total extraction of mandibular third molar: a prospective study
Somatosensory changes in Chinese patients after coronectomy vs. total extraction of mandibular third molar: a prospective study: AbstractObjectivesThis study aimed to quantitatively compare the somatosensory function changes of inferior alveolar nerve (IAN) after mandibular third molar extraction with a surgery protocol of coronectomy, as opposed to the conventional method.Materials and methodsPatients with a lower third molar directly contacting IAN were recruited and assigned either to a test group…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

07:47

Arsenic contamination of drinking water
Removing arsenic from water with an original and modified natural manganese oxide ore: batch kinetic and equilibrium adsorption studies: AbstractArsenic contamination of drinking water is a serious water quality problem in many parts of the world. In this study, a low-cost manganese oxide ore from Vietnam (Vietnamese manganese oxide (VMO)) was firstly evaluated for its performance in arsenate (As(V)) removal from water. This material contains both Mn (25.6%) and Fe (16.1%) mainly in the form of cryptomelane…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

07:46

Automatic detection of reverse-triggering related asynchronies during mechanical ventilation in ARDS patients using flow and pressure signals
Automatic detection of reverse-triggering related asynchronies during mechanical ventilation in ARDS patients using flow and pressure signals: AbstractAsynchrony due to reverse-triggering (RT) may appear in ARDS patients. The objective of this study is to validate an algorithm developed to detect these alterations in patient–ventilator interaction. We developed an algorithm that uses flow and airway pressure signals to classify breaths as normal, RT with or without breath stacking (BS) and patient…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

07:46

Obstructive Sleep Apnea as a Predictor of Abnormal Heart Rate Turbulence
JCM, Vol. 9, Pages 1: Obstructive Sleep Apnea as a Predictor of Abnormal Heart Rate Turbulence: JCM, Vol. 9, Pages 1: Obstructive Sleep Apnea as a Predictor of Abnormal Heart Rate TurbulenceJournal of Clinical Medicine doi: 10.3390/jcm9010001Authors: Urbanik Gać Martynowicz Poręba Podgórski Negrusz-Kawecka Mazur Sobieszczańska Poręba Obstructive sleep apnea (OSA) causes dysfunction of the autonomic nervous system, but the exact mechanism has not been fully understood. The…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

07:46

Updates in Novel Therapies for Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
Updates in Novel Therapies for Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN): AbstractPurpose of ReviewBlastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, clinically aggressive hematologic malignancy that has heterogeneous presentation and can involve the skin, lymph nodes, and bone marrow. Recent advancements in our patho-biologic understanding of the disease have led to the development of new targeted therapies for BPDCN. In this review, we aimed to describe some of the novel…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

07:45

Impact of peripheral neuropathy induced by platinum in first-line chemotherapy on second-line chemotherapy with paclitaxel for advanced gastric cancer
Impact of peripheral neuropathy induced by platinum in first-line chemotherapy on second-line chemotherapy with paclitaxel for advanced gastric cancer: AbstractBackgroundFluoropyrimidine plus platinum, followed by paclitaxel (PTX) plus ramucirumab is a recommended treatment strategy for advanced gastric cancer (AGC). We investigated how peripheral neuropathy (PN), induced by platinum in first-line chemotherapy, affected the tolerability of second-line chemotherapy with PTX (2nd-PTX).MethodsThe subjects…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

07:45

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com, Telephone consultation 11855 int 1193,

Archives of Medicine and Health Sciences, a publication of Yenepoya (Deemed to be) University
July-December 2019Volume 7 | Issue 2Page Nos. 139-322Online since Monday, December 16, 2019Accessed 802 times.PDF access policyJournal allows immediate open access to content in HTML + PDFEPub access policyFull text in EPub is free except for the current issue. Access to the latest issue is reserved only for the paid subscribers.View issue as eBookIssue statisticsRSSHide all abstracts Show selected abstracts Export selected to Add to my listEDITORIALScientistic reductionism and the “dark side”…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:48

Moyamoya disease
Moyamoya disease: Girish Menon, Ajay HegdeArchives of Medicine and Health Sciences 2019 7(2):224-232Moyamoya disease (MMD) is a unique cerebrovascular disease characterized initially by an obliterative vasculopathy followed by a compensatory proliferative vasculopathy. Coined by Suzuki and Takaku in 1969, the term moyamoya (MM) refers to a “puff of smoke” like appearance of small collaterals seen traversing the basal ganglia and thalamus, in response to progressive stenosis and occlusion of supraclinoid…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:46

“When,” “What,” and “How” of complementary feeding: A mixed methods cross-sectional study from a rural medical college
“When,” “What,” and “How” of complementary feeding: A mixed methods cross-sectional study from a rural medical college in central India: Priyanka A Joshi, Shiv H Joshi, Abhishek V RautArchives of Medicine and Health Sciences 2019 7(2):217-223Background and Aim: Undernutrition among under-five children is one of the most important public health problems in India. Despite several years of efforts to tackle undernutrition, India has not been able to make any significant dent on proportion of undernutrition….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:44

Formaldehyde causes detrimental changes on the ventilatory mechanics of the lung. The effect is marked in the initial phase following which the body tries to restore homeostasis.
Effect of exposure to formaldehyde on the forced vital capacity of medical students: A longitudinal study: Dipak Kumar Dhar, Sudeepa ChaudhuriArchives of Medicine and Health Sciences 2019 7(2):212-216Background and Aim: Formaldehyde exposure is one of the various occupational hazards experienced by a doctor during his life. There is consistent and regular exposure to formaldehyde during the gross anatomy dissection classes. Since it vaporizes at room temperature, respiratory system is easily affected….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:43

Effect of exposure to formaldehyde on the forced vital capacity of medical students: A longitudinal study
Effect of exposure to formaldehyde on the forced vital capacity of medical students: A longitudinal study: Dipak Kumar Dhar, Sudeepa ChaudhuriArchives of Medicine and Health Sciences 2019 7(2):212-216Background and Aim: Formaldehyde exposure is one of the various occupational hazards experienced by a doctor during his life. There is consistent and regular exposure to formaldehyde during the gross anatomy dissection classes. Since it vaporizes at room temperature, respiratory system is easily affected….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:40

Does Thyroid dysfunction correlates with iron overload in Eβ thalassemia patients? A study from a tertiary care thalassemia center in India
Does Thyroid dysfunction correlates with iron overload in Eβ thalassemia patients? A study from a tertiary care thalassemia center in India: Shuvraneel Baul, Tuphan Kanti Dolai, Pranab Kumar Sahana, Rajib De, Prakas Kumar Mandal, Prantar ChakrabartiArchives of Medicine and Health Sciences 2019 7(2):206-211Background and Aim: Large number of Haemoglobin E-beta thalassaemia (Hb E/β-thalassaemia) patients show iron overloads and related end-organ damage irrespective of transfusion requirements. The…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:40

Vascular malformation of the upper lip
Vascular malformation of the upper lip: Imran Mohtesham, Chethana Pillappa, Priyal RohanArchives of Medicine and Health Sciences 2019 7(2):258-261Vascular anomalies account as one among the most difficult diagnostic and therapeutic enigmas that can be encountered in the practice of medicine. These lesions are the result of an embryonic abnormality of the vascular system. The main characteristic feature of vascular malformations is that they never show the signs of involution. It is the most common…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:40

Profile of nutritional anemia and its correlation with serum iron, Vitamin B12, and folic acid level among the tribal population of northern districts of West Bengal, India
Profile of nutritional anemia and its correlation with serum iron, Vitamin B12, and folic acid level among the tribal population of northern districts of West Bengal, India: Ankita Dhanuka, Bidyut Krishna Goswami, Sarama Banerjee Goswami, Sudipta ChakrabartiArchives of Medicine and Health Sciences 2019 7(2):201-205Background and Objective: Nutritional anemia is the most common and easily preventable cause of anemia. No comprehensive data regarding the magnitude of this problem are available in the…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:38

Chronic sclerosing osteomyelitis: A case report on a rare complication of tooth extraction
Chronic sclerosing osteomyelitis: A case report on a rare complication of tooth extraction: Valen Dela D’souza, Elvita Martis, Kora Ramya Reddy, Prasanna Kumar Rao, Ritesh KB, Raghavendra Kini, Suraj HegdeArchives of Medicine and Health Sciences 2019 7(2):251-253Chronic osteomyelitis can be a protracted disease often caused by inadequate curettage, injudicious use of antibiotics, and unnecessary delay in treating infected teeth. Failure of treatment of the odontogenic infection may result in decreased…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:37

Alcohol dependence syndrome in suicide attempters: A cross-sectional study in a rural tertiary hospital
Alcohol dependence syndrome in suicide attempters: A cross-sectional study in a rural tertiary hospital: P Sreelatha, G Haritha, V S. S R. Ryali, Ryali P JanakiramanArchives of Medicine and Health Sciences 2019 7(2):195-200Background: Suicidal attempt is a phenomenon with a tremendous impact on the medical and social well-being of the individual, and alcohol abuse/dependence has consistently been implicated in the triggering of suicidal attempt. This complex interaction of alcohol and suicide needs…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:37

Airway concerns in a neonate with Treacher Collins syndrome posted for tracheoesophageal fistula repair
Airway concerns in a neonate with Treacher Collins syndrome posted for tracheoesophageal fistula repair: Sushama Raghunath Tandale, Yogesh Gavali, Subhadra Sinha, Chandraprabhu BirnaleArchives of Medicine and Health Sciences 2019 7(2):319-320Sir,A 3-day-old male, term neonate, weighing 2.9 kg was referred to our institute for tracheoesophageal fistula repair with provisional diagnosis of Treacher Collins syndrome More Details (TCS). Examination revealed tachypnea, heart rate 160 bpm, blood pressure…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:34

Peripheral blood level of natural killer cells in pregnant women with recurrent spontaneous abortion during the 6–12 weeks gestation
Peripheral blood level of natural killer cells in pregnant women with recurrent spontaneous abortion during the 6–12 weeks gestation: Sung-Guk Kim, Mi-Yong Paek, Il Gyong KoArchives of Medicine and Health Sciences 2019 7(2):191-194Background and Aim: The study was performed to confirm the clinical characteristics and peripheral blood level of natural killer (NK) cells as a diagnostic index in women with recurrent spontaneous abortion (RSA) comparing with normal pregnant women. Materials and Methods:…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:34

Childhood blistering distal dactylitis: An uncommon cutaneous manifestation of Staphylococcus aureus
Childhood blistering distal dactylitis: An uncommon cutaneous manifestation of Staphylococcus aureus: Maqbool Saep, Malcolm Pinto, Sateesh K MalkappaArchives of Medicine and Health Sciences 2019 7(2):309-310Blistering distal dactylitis (BDD) is a rare, bacterial skin infection presenting as bullous lesions over the fingers, especially in the age group of <16 years. We present a case of a child presenting with BDD secondary to Staphylococcus aureus infection.A 6-year-old girl was brought to the…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:32

Laryngeal manifestation due to smoking among the pediatric age group
Laryngeal manifestation due to smoking among the pediatric age group – Our experiences at an Indian teaching hospital: Santosh Kumar Swain, Ishwar Chandra Behera, Jatindra Nath MohantyArchives of Medicine and Health Sciences 2019 7(2):186-190Background and Aim: Smoking among the pediatric age group is a public health concern. It has direct link to laryngeal manifestations. Due to increased exposure to smoking, it is affecting the children directly or indirectly through involving upper airway, particularly…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:31

Epilepsy surgery
Epilepsy surgery in India: George C VilanilamArchives of Medicine and Health Sciences 2019 7(2):287-292The history of epilepsy surgery dates back to the era before computerized tomography, magnetic resonance imaging (MRI), positronemission tomogram imaging, and electroencephalogram (EEG). Victor Horsley’s resection of a cortical scar in 1886, based purely on localization is considered as the first epilepsy surgery recorded in history. In India, Prof. Jacob Chandy performed a pediatric hemispherotomy…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:31

Mélange of orbital lesions
Mélange of orbital lesions – A histomorphologic study of 135 cases: Rashi Gupta, Suguna Belur Venugopal, Aparna Muralidhar, V Geethamani, Ankit MalhotraArchives of Medicine and Health Sciences 2019 7(2):181-185Background: The orbit is an important site for primary and secondary diseases. Various tissue types such as osseous, vascular, neural, muscular, and glandular may be involved with specific pathologies. Tumors can secondarily invade the orbit from the periorbital regions including the paranasal…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:31

Expression of c-Met in Primary and Recurrent Hepatocellular Carcinoma
Expression of c-Met in Primary and Recurrent Hepatocellular Carcinoma: Background:The clinical course of hepatocellular carcinoma (HCC) is complicated, because it often recurs and shows multiple lesions, some of which progress to a more malignant form, shortening the life of the patient. The hepatocyte growth factor receptor c-Met has been shown to play an important role in the pathogenesis of HCC, but the influence of c-Met expression on the clinical course of HCC remains to be fully elucidated….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:31

Molecular Barcode Sequencing for Highly Sensitive Detection of Circulating Tumor DNA in Patients with Esophageal Squamous Cell Carcinoma
Molecular Barcode Sequencing for Highly Sensitive Detection of Circulating Tumor DNA in Patients with Esophageal Squamous Cell Carcinoma: Introduction:Next-generation sequencing (NGS) with molecular barcodes (MB) is a novel method that enables the highly sensitive detection of circulating tumor DNA (ctDNA) in a relatively wide range of genes. Objective:The aim of this study was to examine the utility of NGS with MB for detecting ctDNA in patients with esophageal squamous cell carcinoma (ESCC). Methods:Five…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:31

Plasma Cell Gingivitis with Cheilitis
A Rare Case of Plasma Cell Gingivitis with Cheilitis: Background. Plasma cell gingivitis (PCG) is a rare condition of the gingiva, characterized histopathologically by infiltration of plasma cells in connective tissue. Hypersensitivity reaction due to antigen is considered as primary etiological factor. Case Presentation. The present case is of an 18-year-old male patient suffering from gingival enlargement along with cheilitis. Histopathological and immunohistochemistry of tissue revealed lesion…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:29

Epstein-Barr virus-positive diffuse large B cell lymphoma, not otherwise specified, carrying a t(19;22)(q13;q11) translocation
Epstein-Barr virus-positive diffuse large B cell lymphoma, not otherwise specified, carrying a t(19;22)(q13;q11) translocation: References1.Castillo JJ, Beltran BE, Miranda RN et al (2018) EBV-positive diffuse large B-cell lymphoma, not otherwise specified: 2018 update on diagnosis, risk-stratification and management. Am J Hematol 93:953–962CASArticleGoogle Scholar2.Martin-Subero JI, Ibbotson R, Klapper W et al (2007) A comprehensive genetic and histopathologic analysis identifies two subgroups of…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:29

Misfolding linked mutations of SERPINA1 gene are uncommon in preeclampsia
Misfolding linked mutations of SERPINA1 gene are uncommon in preeclampsia: Chandrakala Nagarajappa, Sheela Shikaripur Rangappa, Sharath BalakrishnaArchives of Medicine and Health Sciences 2019 7(2):177-180Background: Alpha-1 antitrypsin (A1AT) is a protease inhibitor that plays an important role in regulating oxidative stress in preeclampsia (PE). Recent studies have shown that A1AT is misfolded in PE. However, the cause of A1AT misfolding is not known. Mutations in SERPINA1 gene is an established…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:28

Ophthalmological perspectives of toxic epidermal necrolysis
Ophthalmological perspectives of toxic epidermal necrolysis: Gayatree Mohanty, Shovna Dash, Manoj Kumar, Devanshi DesaiArchives of Medicine and Health Sciences 2019 7(2):254-257Toxic epidermal necrolysis (TEN) is as rare as two cases per million per year, but the ocular manifestations and sequelae are very severe. We present a case series of seven patients admitted to the intensive care unit in a tertiary hospital with a diagnosis of TEN describing the extent of ocular involvement, its response to…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:28

Prevalence and distribution of dental agenesis among orthodontic patients
Prevalence and distribution of dental agenesis among orthodontic patients of Kathmandu, Nepal: Sanjay Prasad Gupta, Shristi RauniyarArchives of Medicine and Health Sciences 2019 7(2):172-176Background: Tooth agenesis is the most common developmental dental anomaly in humans with a wide variability of distribution among different population. Objective: The objective of this study was to find out the prevalence of dental agenesis among Nepalese orthodontic patients of Kathmandu and its occurrence with…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:28

Intracranial hypertension secondary to levofloxacin-therapy
Intracranial hypertension secondary to levofloxacin-therapy: Jamir Pitton Rissardo, Ana Letícia Fornari CapraraArchives of Medicine and Health Sciences 2019 7(2):313-316Idiopathic intracranial hypertension (ICH) is characterized by elevated intracranial pressure without an evident etiology. Here, we report the case of an adult male who presented with headache, diplopia, blurred vision, and nausea. The patient stated that he had searched a general practitioner 1 week ago because he had experienced…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:27

Enterococcicidal activity of chlorine dioxide and lemon extract endorse them as contemporary root canal irrigants
Enterococcicidal activity of chlorine dioxide and lemon extract endorse them as contemporary root canal irrigants: Ramamurthi Arularasi Aberna, G Mohan, S SaranyaArchives of Medicine and Health Sciences 2019 7(2):167-171Background and Objective: Enterococcus faecalis offers challenges when present in an anatomically challenging and inaccessible site such as root canal and are instrumental in treatment failures. This emphasizes the need for irrigants besides mechanical instrumentation in root canal…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:27

Gilles de la Tourette syndrome (GTS) is a neurodevelopmental condition characterized by multiple motor and vocal tics with a chronic course. With its multifaceted range of symptoms, GTS lies at the crossroads of neurology and psychiatry.
Gilles de la Tourette syndrome: An overview: Andrea Nani, Andrea E CavannaArchives of Medicine and Health Sciences 2019 7(2):277-283Gilles de la Tourette syndrome (GTS) is a neurodevelopmental condition characterized by multiple motor and vocal tics with a chronic course. With its multifaceted range of symptoms, GTS lies at the crossroads of neurology and psychiatry. This review article provides an outline of GTS, encompassing its extended clinical phenomenology, pathophysiology, and treatment options….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:27

Lactate dehydrogenase and maternal and perinatal outcome in preeclamptic women
Lactate dehydrogenase and maternal and perinatal outcome in preeclamptic women: Simmi Kharb, N Bhandari, A Singh, A GuptaArchives of Medicine and Health Sciences 2019 7(2):163-166Background: Preeclampsia is a condition that is characterized by hypertension and proteinuria occurring after 28 weeks of gestation. It complicates 5%–8% of all pregnancies. Lactate dehydrogenase (LDH) is an intracellular enzyme and its level is increased in preeclamptic women due to cellular death. Preeclampsia is a multisystem…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:27

Scientistic reductionism and the “dark side” of modern medicine: A personal reflection
Scientistic reductionism and the “dark side” of modern medicine: A personal reflection: Bhaskara P ShelleyArchives of Medicine and Health Sciences 2019 7(2):139-150It is reasonable to expect the doctor to recognize that science may not have all the answers to problems of health and healing.– Norman CousinsOpinions cannot survive if one has no chance to fight for them.– Thomas Mann A Prologue: Ancient Wisdom of Science and Health in Indian Medicine Top“Open-minded people don’t care to be right,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:26

Cyberchondria: Implications of online behavior and health anxiety as determinants
Cyberchondria: Implications of online behavior and health anxiety as determinants: Denelle Mohammed, Sara Wilcox, Camille Renee, Christine Janke, Niki Jarrett, Anjelika Evangelopoulos, Chasity Serrano, Nazmin Tabassum, Natashia Turner, Melody Theodore, Aleksandar Dusic, Rana ZeineArchives of Medicine and Health Sciences 2019 7(2):154-162Background: Cyberchondria is excessive worrying about one’s health that develops following internet search for medical and health information. Aim: This study investigates…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:25

Giant cell tumor tendon sheath at inguinal region masquerading as enlarged lymph node
Giant cell tumor tendon sheath at inguinal region masquerading as enlarged lymph node: Minakshi Chouhan, Sheetal Arora, Neetika Gupta, Rashmi AroraArchives of Medicine and Health Sciences 2019 7(2):262-264Giant cell tumor of the tendon sheath (GCTTS) is a benign tumor and is the second most common tumor of the hand after ganglion cysts. It is a slow-growing benign lesion of the soft tissues. The etiology of GCTTS is not clear. Although GCTTS most commonly presents in a digit of the hand, it may also…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:25

Recurrent choroid plexus carcinoma
Recurrent choroid plexus carcinoma: Ravi C Ambalath, Meher L Konatam, Stalin Bala, Sadashivudu GundetiJournal of Dr. NTR University of Health Sciences 2019 8(4):286-289Plexus-chorioideuscarcinomataor malignant plexus papillomas are very rare malignancy; only few cases have been described in the literature. A 2.5-year-old girl, known case of choroid plexus carcinoma, presented with complaints of weakness of right upper limb and lower limb, decreased activity, altered sensorium and vomiting. After…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:24

New simple unicortex locking intramedullary fixation of forearm shaft fracture: A Case report
New simple unicortex locking intramedullary fixation of forearm shaft fracture: A Case report: Hyon-Chol Kim, Hak-Su KimJournal of Dr. NTR University of Health Sciences 2019 8(4):264-267We have used nonlocking nails in patients with small intramedullary canals for the fixation of segmental fractures of the radius and ulna. We report a patient with the Monteggia fracture dislocation (the ulnar shaft segmental fracture) treated by new simple unicortex locking intramedullary fixation.

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:24

Poisoned to paralysed: A case of organophosphate induced delayed neuropathy
Poisoned to paralysed: A case of organophosphate induced delayed neuropathy: Mahadevaiah Mahesh, Sindhu Rao Malla, Chilkunda Raviprakash Venkatesh, Varsha TandureJournal of Dr. NTR University of Health Sciences 2019 8(4):281-283Organophosphate (OP) compound poisoning is a global public health problem and is a social calamity, especially in a developing country like India. Acute cholinergic crisis and intermediate syndrome after OP compound consumption are well-known and well-documented. Delayed neurological…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:24

Cystic lateral neck mass: Papillary thyroid carcinoma metastases with concomitant lymphangioma
Cystic lateral neck mass: Papillary thyroid carcinoma metastases with concomitant lymphangioma: Chitturi Ramya, Sripriya Krishnan, Inuganti Venkata Renuka, Sowjanya Krishna Sree KesaboyinaJournal of Dr. NTR University of Health Sciences 2019 8(4):261-263The most common presentation of papillary carcinoma thyroid is a solitary thyroid nodule but it is also known to present as cystic metastatic deposits in the neck. It has an indolent course and good prognosis. Although ultrasound is a commonly used…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:24

A rare case of rickettsial infection presented as febrile delirium in a 4 years old child
A rare case of rickettsial infection presented as febrile delirium in a 4 years old child from a government hospital, Andhra Pradesh, India: G S Rama Prasad, Suhasini Mekala, Naresh GadaganiJournal of Dr. NTR University of Health Sciences 2019 8(4):272-275We report here a documented case of Febrile delirium in a child caused by Rickettsiae. Rickettsial infection is a relatively under-diagnosed entity in children with fever and rash, probably due to low index of suspicion and the lack of definitive…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:23

Hemodialysis arteriovenous fistula maturation and role of perioperative vascular mapping
Hemodialysis arteriovenous fistula maturation and role of perioperative vascular mapping: Ramesh Dasari, Siva Parvathi Karanam, Anil Kumar, A Tyagi, Siva Kumar, AY LakshmiJournal of Dr. NTR University of Health Sciences 2019 8(4):257-260Introduction: The arteriovenous fistula (AVF) is the preferred access in patients starting on maintenance hemodialysis. The vasculature of the upper limb has a dominant role in determining the successful outcome of AVF surgery. Hence, we aimed to determine the various…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:23

A study on association of epstein barr virus in oral squamous cell carcinoma using polymerase chain reaction technique.”
“A study on association of epstein barr virus in oral squamous cell carcinoma using polymerase chain reaction technique.”: M Mary Prathyusha, Kiran K Kattappagari, Deepika Chowdary, Poosarla C Shekar, Dasarathi Alivelu, Baddam V R. ReddyJournal of Dr. NTR University of Health Sciences 2019 8(4):233-237Background and Aims: Head and neck cancer is the most common type of cancer in word wide and Oral squamous cell carcinoma (OSCC) accounts for 90% of oral cancers and it represents the sixth most frequent…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:23

The role of FNAC in diagnostically challenging malignant lesions of breast
The role of FNAC in diagnostically challenging malignant lesions of breast: Rajyalakshmi Rallapalli, Lakshmi V Chavali, Bhaskar V Rani, Ramana V Kada, Beulah P MaddiralaJournal of Dr. NTR University of Health Sciences 2019 8(4):250-256Background: Fine needle aspiration cytology is a simple investigation to evaluate the malignant tumors of the breast when compared to tru-cut biopsy. It is invaluable in the diagnosis of the common invasive carcinoma of the breast including its subtypes. The morphology…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:23

Infrarenal aortoiliac occlusion with metastatic gas gangrene
An unusual presentation of infrarenal aortoiliac occlusion with metastatic gas gangrene: J Abdul Gafoor, O Joji Reddy, D Harinath, N BhavanaJournal of Dr. NTR University of Health Sciences 2019 8(4):276-280Gas gangrene is a term reserved for fulminant soft tissue infections caused by Clostridium species. The posttraumatic form of gas gangrene is caused by Clostridium perfringens. Nontraumatic, or spontaneous, gas gangrene is even more rare and is usually caused by Clostridium septicum in two-thirds…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:22

Antimicrobial efficacy of herbal extracts combined with zinc oxide eugenol as an obturating material in primary teeth – An in vitro study
Antimicrobial efficacy of herbal extracts combined with zinc oxide eugenol as an obturating material in primary teeth – An in vitro study: Senapathi Navaneet, Sridhar Muktineni, Sai Sankar J. Avula, Pranitha Kakarla, Harish C Kommineni, K AmruthavalliJournal of Dr. NTR University of Health Sciences 2019 8(4):244-249Background and Aims: The aim of this study is to evaluate the antimicrobial efficacy of synthetic obturating material (Zinc oxide eugenol) individually and combined with medicinal plant…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:22

Complete androgen insensitivity syndrome: A case report
Complete androgen insensitivity syndrome: A case report: Suresh K JariwalaJournal of Dr. NTR University of Health Sciences 2019 8(4):284-285Technology cannot replace clinical acumen. Think of complete androgen insensitivity syndrome (CAIS) in a female child with inguinal hernia. Diagnosis was missed in our patient when she presented with inguinal hernia the first time. Karyotyping should be done. Sex of rearing in CAIS is female. Chances of tumor development in retained testis are low. Testis helps…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:22

Non-Valvular Atrial Fibrillation : Extended and One-Time Screening Versus No Screening
Cost-Effectiveness of Extended and One-Time Screening Versus No Screening for Non-Valvular Atrial Fibrillation in the USA: AbstractBackgroundThere is limited evidence on the clinical and cost benefits of screening for atrial fibrillation (AF) with electrocardiogram (ECG) in asymptomatic adults.MethodsWe adapted a previously published Markov model to evaluate the clinical and economic impact of one-time screening for non-valvular AF (NVAF) with a single 12-lead ECG and a 14-day extended screening…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:21

Mutant C9orf72 human iPSC‐derived astrocytes cause non‐cell autonomous motor neuron pathophysiology
Mutant C9orf72 human iPSC‐derived astrocytes cause non‐cell autonomous motor neuron pathophysiology: Main pointsHuman iPSC‐derived astrocytes harboring C9orf72 mutations recapitulate key aspects of ALS pathology and cause non‐cell autonomous pathophysiology in human iPSC‐derived motor neurons. The pathophysiology induced in motor neurons by ALS astrocytes is characterized by a progressive loss of action potential output due to a decrease in voltage‐gated sodium and potassium currents. CRISPR/Cas9…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:21

Late‐onset interstitial nephritis in a patient with drug‐induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms
Late‐onset interstitial nephritis in a patient with drug‐induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms: AbstractDrug‐induced hypersensitivity syndrome (DIHS), also referred to as drug reaction with eosinophilia and systemic symptoms (DRESS), is a severe hypersensitivity drug reaction affecting the skin and multiple internal organ systems. We report a 47‐year‐old man with DIHS/DRESS and comorbidities (fulminant type 1 diabetes mellitus, valsartan‐induced photosensitivity,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:20

Concomitant BRAF Mutation in Hairy Cell Leukemia and Papillary Thyroid Cancer: Case Report
Concomitant BRAF Mutation in Hairy Cell Leukemia and Papillary Thyroid Cancer: Case Report: Hairy cell leukemia (HCL) is rare type of leukemia. This neoplasm is well-known to present with pancytopenia and splenomegaly. HCL is associated with BRAF mutation in 100% of cases. It is also associated with hematological and oncological malignancies such as melanoma and papillary thyroid cancer. Although the association of both cancers (HCL and papillary thyroid cancer) with BRAF mutation is well established…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:20

Multimodal Treatment of Extragonadal Choriocarcinoma with Multiple Brain and Lung Metastases: A Case Report
Multimodal Treatment of Extragonadal Choriocarcinoma with Multiple Brain and Lung Metastases: A Case Report: Choriocarcinoma is a highly aggressive germ cell tumor and can metastasize to the brain. Although brain metastasis has a poor prognosis, the optimal treatment strategy remains unclear due to its low incidence. A 33-year-old man presenting with multiple lung nodules on chest radiography was referred to our hospital. Computed tomography revealed bilateral lung nodules and a large pelvic mass,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:20

Complete laparoscopic duodenojejunostomy for superior mesenteric artery syndrome: Linear stapled closure of the common enterotomy
Complete laparoscopic duodenojejunostomy for superior mesenteric artery syndrome: Linear stapled closure of the common enterotomy: AbstractSuperior mesenteric artery syndrome can lead to duodenal obstruction due to vascular compression. We treated a patient with superior mesenteric artery syndrome by performing a complete laparoscopic duodenojejunostomy with a linear stapled closure of the common enterotomy. A 72‐year‐old woman presented with nausea, vomiting, and weight loss. CT revealed superior…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:20

Comparison of Ziehl-Neelsen’s stain, fluorescent stain with CBNAAT of sputum for the diagnosis of pulmonary tuberculosis
Comparison of Ziehl-Neelsen’s stain, fluorescent stain with CBNAAT of sputum for the diagnosis of pulmonary tuberculosis: Goteti V Padmaja, Kasukurthi Srujana, Chittari SadhanaJournal of Dr. NTR University of Health Sciences 2019 8(4):238-243Introduction: Pulmonary tuberculosis remains one of the most dangerous communicable diseases. More than two billion people are estimated to be infected with Mycobacterium tuberculosis. In 2017, approximately 10 million individuals became ill with tuberculosis,among…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:19

Pleomorphic adenoma of soft palate with extensive squamous metaplasia – A diagnostic enigma
Pleomorphic adenoma of soft palate with extensive squamous metaplasia – A diagnostic enigma: Rashmi Patnayak, Sandip Mohanty, Anjan Kumar Sahoo, Adya Kinkara Panda, Amitabh JenaJournal of Dr. NTR University of Health Sciences 2019 8(4):268-271Pleomorphic adenoma is the most common salivary gland tumor. It can have a wide range of morphological spectrum. But extensive squamous metaplasia mimicking squamous cell carcinoma is quite uncommon. Palate is a common site for minor salivary gland tumor. Less…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:17

Safety and efficacy of VB-111, an anti-cancer gene-therapy, in patients with recurrent glioblastoma: results of a phase I/II study
Safety and efficacy of VB-111, an anti-cancer gene-therapy, in patients with recurrent glioblastoma: results of a phase I/II study: AbstractBackgroundVB-111 is a non-replicating adenovirus carrying a Fas-chimera transgene, leading to targeted apoptosis of tumor vascular endothelium and induction of a tumor specific immune response. This phase I/II study evaluated the safety, tolerability and efficacy of VB-111 with and without bevacizumab in recurrent glioblastoma (rGBM).MethodsPatients with rGBM…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:17

VB-111 combined with bevacizumab vs. bevacizumab monotherapy in patients with recurrent glioblastoma (GLOBE)
A randomized controlled phase III study of VB-111 combined with bevacizumab vs. bevacizumab monotherapy in patients with recurrent glioblastoma (GLOBE): AbstractBackgroundOfranergene obadenovec (VB-111) is an anti-cancer viral therapy that demonstrated in a Phase-II study a survival benefit for patients with recurrent glioblastoma (rGBM) who were primed with VB-111 monotherapy that was continued after progression with concomitant bevacizumab.MethodsThis pivotal phase-III randomized, controlled trial…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:15

A new detection method for EMG activity monitoring
A new detection method for EMG activity monitoring: AbstractThis paper introduces a new approach for electromyography (EMG) activity monitoring based on an improved version of the adaptive linear energy detector (ALED), a widely used technique in voice activity detection. More precisely, we propose a modified ALED technique (named M-ALED) to improve the method’s robustness with respect to noise. To achieve this objective, M-ALED relies on the Teager-Kaiser operator for signal pre-conditioning to…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:15

Quality of life in the FOXFIRE, SIRFLOX, and FOXFIRE‐Global randomised trials of selective internal radiotherapy for metastatic colorectal cancer
Quality of life in the FOXFIRE, SIRFLOX, and FOXFIRE‐Global randomised trials of selective internal radiotherapy for metastatic colorectal cancer: Selective internal radiotherapy (SIRT) is a liver‐directed treatment involving injection of yttrium‐90 microspheres in to the blood supply of liver tumours. There are very few studies assessing health related quality of life (HRQOL) in patients treated with SIRT. Patients with liver metastases from colorectal cancer (CRC) were randomised in the FOXFIRE…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:12

CTLA4 blockade promotes vessel normalization in breast tumors via the accumulation of eosinophils
CTLA4 blockade promotes vessel normalization in breast tumors via the accumulation of eosinophils: Immune checkpoint blockade (ICB) has shown long‐term survival benefits, but only in a small fraction of cancer patients. Recent studies suggest that improved vessel perfusion by ICB positively correlates with its therapeutic outcomes. However, the underlying mechanism of such process remains unclear. Here, we show that anti‐cytotoxic T‐lymphocyte‐associated protein 4 (CTLA4) treatment‐induced tumor…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:11

A Biomimicking Polymeric Cryogel Scaffold for Repair of Critical-Sized Cranial Defect in a Rat Model
A Biomimicking Polymeric Cryogel Scaffold for Repair of Critical-Sized Cranial Defect in a Rat Model: Tissue Engineering Part A, Volume 25, Issue 23-24, Page 1591-1604, December 2019. AbstractMineralized polymeric cryogels with interconnective macroporous structure have demonstrated their potential as promising scaffolding material in bone tissue engineering. However, their capability in inducing osteogenic differentiation of mesenchymal stem cells (MSCs) in vitro and osteogenesis in vivo has not…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:03

Reinforcing the primary immunotherapy modulators against acute leukemia; monoclonal antibodies in AML
Reinforcing the primary immunotherapy modulators against acute leukemia; monoclonal antibodies in AML: Immunotherapy, Ahead of Print. Recent therapeutic advances in cancer treatment recruit immune system potentiation against malignant cells. Numerous ongoing clinical trials on immunotherapy methods, either monotherapy or combination therapy, are investigating the impeding factors on the way of acute myeloid leukemia (AML) treatment. Due to the genetic diversity in AML progenitors, combining various…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:02

Elevated Levels of Platelet Activating Factor and Its Acetylhydrolase Indicate High Risk of Kawasaki Disease
Elevated Levels of Platelet Activating Factor and Its Acetylhydrolase Indicate High Risk of Kawasaki Disease: Journal of Interferon &Cytokine Research, Ahead of Print. AbstractKawasaki disease (KD) is a systemic vasculitis in children, which is related to inflammation and abnormal activation of immune system. Platelet activating factor (PAF) and its acetylhydrolase (PAF-AH) may play an important role in the pathogenesis of KD. This study aimed to investigate diagnosis and prognostic value of…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:59

Copper-induced oxidative stress, initiation of antioxidants and phytoremediation potential of flax ( Linum usitatissimum L.) seedlings grown under the mixing of two different soils of China
Copper-induced oxidative stress, initiation of antioxidants and phytoremediation potential of flax ( Linum usitatissimum L.) seedlings grown under the mixing of two different soils of China: AbstractFlax (Linum usitatissimum L.), one of the oldest cultivated crops, continues to be widely grown for oil, fiber and food. Furthermore, the plants show a metal tolerance dependent on species so is ideal for research. Present study was conducted to find out the influence of copper (Cu) toxicity on plant…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:58

Industrial water pollution and transboundary eco-compensation: analyzing the case of Songhua River Basin, China
Industrial water pollution and transboundary eco-compensation: analyzing the case of Songhua River Basin, China: AbstractAs eco-compensation is considered an effective economic instrument for controlling the industrial water pollution in transboundary basin, this study aims to explore a transboundary eco-compensation mechanism for Songhua River Basin that is one of the seven major drainage basins in China. Using a panel dataset of eleven cities in this basin tracked from 1992 to 2016, we empirically…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:58

‘I will do my very best!’ Children who engage in positive self-talk about effort can boost their math achievement
‘I will do my very best!’ Children who engage in positive self-talk about effort can boost their math achievement: (Society for Research in Child Development) Children who think poorly of themselves often underachieve in school. A new Dutch study tested whether a simple mental activity — having children with low self-confidence say favorable, encouraging words to themselves — could boost their achievement. The study found that children who engaged in this kind of self-talk improved their math performance…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:57

Canalis Sinuosus Damage after Immediate Dental Implant Placement in the Esthetic Zone
Canalis Sinuosus Damage after Immediate Dental Implant Placement in the Esthetic Zone: Dental implant failure in the anterior maxilla can be caused by the range of the features. One of them is neighboring neurovascular structure damage, such as the canalis sinuosus (CS), that carries the superior anterior alveolar nerve. The aim of the report is to demonstrate clinical symptomatology and radiographic signs of CS damage in a 45-year-old female patient who underwent upper left lateral incisor extraction…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:57

Urotensin-II-Targeted Liposomes as a New Drug Delivery System towards Prostate and Colon Cancer Cells
Urotensin-II-Targeted Liposomes as a New Drug Delivery System towards Prostate and Colon Cancer Cells: Urotensin-II (UT-II) and its receptor (UTR) are involved in the occurrence of different epithelial cancers. In particular, UTR was found overexpressed on colon, bladder, and prostate cancer cells. The conjugation of ligands, able to specifically bind receptors that are overexpressed on cancer cells, to liposome surface represents an efficient active targeting strategy to enhance selectivity and…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:57

Recovering of Dizziness of a Patient with Sinusitis after Root Canal Therapy for Upper Second Molar
Recovering of Dizziness of a Patient with Sinusitis after Root Canal Therapy for Upper Second Molar: This case report illustrates the recovery of dizziness of a young healthy patient after root canal therapy of upper second molar. The patient developed dizziness and unbalanced walking four months ago. After cardiac, ENT, neurological, physiotherapy and medical investigations, his entire checkup showed no abnormalities. The patient visited a dental clinic for a routine checkup; after dental clinical…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:57

Continuous Professional Oral Health Care Intervention Improves Severe Aspiration Pneumonia
Continuous Professional Oral Health Care Intervention Improves Severe Aspiration Pneumonia: Professional oral health care (POHC) is known to prevent aspiration pneumonia in patients with dysphagia and/or those at the perioperative stage of surgery. However, the effect of POHC on patients suffering from aspiration pneumonia remains unknown. Here, we report a case where continual POHC intervention improved severe aspiration pneumonia. A 74-year-old male patient with a brain infarction suffered from…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:56

One-year outcome of coenzyme Q10 supplementation in ADCK3 ataxia (ARCA2)
One-year outcome of coenzyme Q10 supplementation in ADCK3 ataxia (ARCA2): AbstractBackgroundThe recessive ataxia ARCA2 is a rare disorder characterized by Coenzyme Q10 (CoQ10) deficiency due to biallelic mutations in ADCK3 gene. Despite the pathophysiological role, available data are not univocal on clinical efficacy of CoQ10 supplementation in ARCA2. Here we described the long-term motor outcome of 4 untreated ARCA2 patients prospectively followed-up for one year after starting CoQ10 oral supplementation…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:56

Radiological and toxicity risk exposures of oil based mud: health implication on drilling crew in Niger Delta
Radiological and toxicity risk exposures of oil based mud: health implication on drilling crew in Niger Delta: AbstractNaturally occurring radioactive materials (NORMs) and the presence of toxic metals in drilling fluids/their additives have raised research interests in recent times owing to the risks associated with the exposure times for drillers of petroleum wells. In this study, two drilling fluids A and B were formulated, while two other Mud Samples C and D were obtained from drilled shale and…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:56

Recommended care and care adherence following a diagnosis of Lynch syndrome: a mixed-methods study
Recommended care and care adherence following a diagnosis of Lynch syndrome: a mixed-methods study: AbstractBackgroundLynch syndrome (LS) is the most common hereditary colorectal cancer (CRC) syndrome. This study assesses trends in diagnosis of LS and adherence to recommended LS-related care in a large integrated healthcare organization (~ 575,000 members).MethodsElectronic medical record (EMR) data (1999–2015) were examined to identify patients with a diagnosis of LS. We examined their LS-associated…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:56

Patients with pathogenic variants for breast cancer other than BRCA1 and BRCA2: qualitative interviews about health care experiences
Patients with pathogenic variants for breast cancer other than BRCA1 and BRCA2: qualitative interviews about health care experiences: AbstractBackgroundGenetic testing for hereditary cancer syndromes has been revolutionized by next-generation sequencing, which allows for simultaneous review of numerous genes. Multigene panels are regularly offered to patients because of their scope and decreased cost and turnaround time. However, many genes included on larger panels have not been studied as extensively…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:55

Toxicity testing in the 21st century: progress in the past decade and future perspectives
Toxicity testing in the 21st century: progress in the past decade and future perspectives: AbstractAdvances in the biological sciences have led to an ongoing paradigm shift in toxicity testing based on expanded application of high-throughput in vitro screening and in silico methods to assess potential health risks of environmental agents. This review examines progress on the vision for toxicity testing elaborated by the US National Research Council (NRC) during the decade that has passed since the…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:55

Idiopathic nephrotic syndrome and serum permeability factors: a molecular jigsaw puzzle
Idiopathic nephrotic syndrome and serum permeability factors: a molecular jigsaw puzzle: AbstractNephrotic syndrome is traditionally defined using the triad of edema, hypoalbuminemia, and proteinuria, but this syndrome is very heterogeneous and difficult to clarify. Its idiopathic form (INS) is probably the most harmful and essentially comprises two entities: minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS). We will consider some hypotheses regarding the mechanisms underlying…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:55

Plakophilins and their roles in diseased states
Plakophilins and their roles in diseased states: AbstractTissue homeostasis is maintained by several cellular mechanisms and an imbalance may lead to diseased states. Here, the plakophilins 1, 2 and 3 operate as structural components and stabilize desmosomal cell-cell contacts. In their non-junctional states, they serve as regulators of signaling programs and control varied cellular processes that range from transcription, mRNA abundance, protein synthesis, growth, proliferation, migration to invasion…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:55

Arsenic-Containing Qinghuang Powder (青黄散) is an Alternative Treatment for Elderly Acute Myeloid Leukemia Patients Refusing Low-Intensity Chemotherapy
Arsenic-Containing Qinghuang Powder (青黄散) is an Alternative Treatment for Elderly Acute Myeloid Leukemia Patients Refusing Low-Intensity Chemotherapy: AbstractObjectiveTo analyze the overall survival (OS) of elderly acute myeloid leukemia (AML) patients treated with oral arsenic-containing Qinghuang Powder (青黄散, QHP) or low-intensity chemotherapy (LIC).MethodsForty-two elderly AML patients treated with intravenous or subcutaneous LIC (1 month for each course, at least 3 courses) or oral QHP (3 months…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:53

Reducing avoidable chest pain admissions and implementing high-sensitivity troponin testing
Reducing avoidable chest pain admissions and implementing high-sensitivity troponin testing: NHS accident and emergency departments see 0.5 million patients presenting with a cardiac condition each year. The accurate assessment of chest pain and subsequent diagnosis or exclusion of myocardial infarction (MI) represent a significant challenge, with important consequences on patient outcome and healthcare resources. We conducted a cross-sectional analysis of patients admitted with cardiac chest pain…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:53

A toothpaste tablet to eliminate plastic tubes
Canadian duo invent a toothpaste tablet to eliminate plastic tubes: “Toothpaste tubes take over 500 years to break down and are unable to be recycled. We’ve developed toothpaste tablets that remove the need for a tube altogether.”: submitted by /u/mvea [link]

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:51

An anomalous case of the flexor carpi radialis with an excessive muscular bundle
An anomalous case of the flexor carpi radialis with an excessive muscular bundle: AbstractA variation of the flexor carpi radialis with an excessive muscular bundle was found on the right forearm of a Japanese male cadaver. The flexor carpi radialis had two heads, medial one arising from the medial epicondyle of the humerus, and the other, a variant excessive muscular bundle, arising from the bicipital aponeurosis deep at the medial edge of the tendon of biceps brachii. There was also a muscular…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:51

Saccharomyces boulardii reduces the mean intensity of infection in mice caused by the consumption of liver contaminated by Toxocara canis
Saccharomyces boulardii reduces the mean intensity of infection in mice caused by the consumption of liver contaminated by Toxocara canis: AbstractProbiotics have shown promising results as a potential method to control toxocariasis in mice inoculated with embryonated eggs of Toxocara canis. This study aimed to evaluate the protective effect of Saccharomyces boulardii in mice fed in natura chicken livers infected with T. canis. Twenty 15-day-old male Sussex chickens were inoculated with 300 T. canis…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:51

Harper’s Textbook of Pediatric Dermatology, 2 Volume Set, 4th Edition
Harper’s Textbook of Pediatric Dermatology, 2 Volume Set, 4th Edition: A consummate classic with a fresh approach to pediatric dermatologyChildren´s skin is different. Maturation affects the epidermal barrier, the cutaneous microbiome, adnexal structures, vasculature, and transcutaneous absorption of drugs. The immature skin is more susceptible to pathogens and environmental disruption. Many genetic disorders are either present at birth or manifest early in childhood. Skin diseases thus present…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:50

Pharmacoepidemiology, 6th Edition
Pharmacoepidemiology, 6th Edition: This classic, field-defining textbook, now in its sixth edition, provides the most comprehensive guidance available for anyone needing up-to-date information in pharmacoepidemiology. This edition has been fully revised and updated throughout and continues to provide a rounded view on all perspectives from academia, industry and regulatory bodies, addressing data sources, applications and methodologies with great clarity.Read More…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:50

Exosomal miRNA Let-7 from Menstrual Blood-Derived Endometrial Stem Cells Alleviates Pulmonary Fibrosis through Regulating Mitochondrial DNA Damage
Exosomal miRNA Let-7 from Menstrual Blood-Derived Endometrial Stem Cells Alleviates Pulmonary Fibrosis through Regulating Mitochondrial DNA Damage: Idiopathic pulmonary fibrosis (IPF) is a prototype of chronic, progressive, and fibrotic lung disease with high morbidity and high mortality. Menstrual blood-derived stem cells (MenSCs) have proven to be an attractive tool for the treatment of acute lung injury and fibrosis-related diseases through immunosuppression and antifibrosis. However, whether…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:50

Is Movember synonymous with moustaches or men’s health? An examination of internet search activity for prostate and testicular cancer during the campaign.
Is Movember synonymous with moustaches or men’s health? An examination of internet search activity for prostate and testicular cancer during the campaign.: Is Movember synonymous with moustaches or men’s health? An examination of internet search activity for prostate and testicular cancer during the campaign.Ir J Med Sci. 2019 Dec 14;:Authors: Khan JS, Papa NP, Davis NF, Wrafter PF, Kelly JC, Dowling CM, D’Arcy FTAbstract BACKGROUND: The Movember campaign encourages men to grow a moustache…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:49

Effects of bamboo shoots (Bambusa balcooa) on thyroid hormone synthesizing regulatory elements at cellular and molecular levels in thyrocytes.
Effects of bamboo shoots (Bambusa balcooa) on thyroid hormone synthesizing regulatory elements at cellular and molecular levels in thyrocytes.: Related ArticlesEffects of bamboo shoots (Bambusa balcooa) on thyroid hormone synthesizing regulatory elements at cellular and molecular levels in thyrocytes.J Ethnopharmacol. 2019 Dec 12;:112463Authors: Sarkar D, Chandra AK, Chakraborty A, Ghosh S, Chattopadhyay S, Singh LH, Ray IAbstract ETHNOPHARMACOLOGICAL RELEVANCE: Bamboo shoots (BS) are consumed…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:46

Copaiba oleoresin has topical antinociceptive activity in a UVB radiation-induced skin-burn model in mice.
Copaiba oleoresin has topical antinociceptive activity in a UVB radiation-induced skin-burn model in mice.: Related ArticlesCopaiba oleoresin has topical antinociceptive activity in a UVB radiation-induced skin-burn model in mice.J Ethnopharmacol. 2019 Dec 12;:112476Authors: Becker G, Brusco I, Casoti R, Lay Marchiori MC, Cruz L, Trevisan G, Oliveira SMAbstract ETHNOPHARMACOLOGICAL RELEVANCE: Copaiba oleoresin, extracted from Copaifera L., is used as a wound healing, analgesic, antimicrobial…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:45

Efficacy and safety of indigo naturalis ointment in Treating Atopic Dermatitis: A randomized clinical trial.
Efficacy and safety of indigo naturalis ointment in Treating Atopic Dermatitis: A randomized clinical trial.: Efficacy and safety of indigo naturalis ointment in Treating Atopic Dermatitis: A randomized clinical trial.J Ethnopharmacol. 2019 Dec 12;:112477Authors: Lin YK, Chang SH, Yang CY, See LC, Lee BH, Shih IHAbstractETHNOPHARMACOLOGICAL RELEVANCE: Indigo naturalis, a herbal medicine with a history of use dating back to ancient times, may be a good alternative topical treatment for atopic dermatitis…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:43

The Matrisome during Aging and Longevity: A Systems-Level Approach toward Defining Matreotypes Promoting Healthy Aging.
The Matrisome during Aging and Longevity: A Systems-Level Approach toward Defining Matreotypes Promoting Healthy Aging.: Related ArticlesThe Matrisome during Aging and Longevity: A Systems-Level Approach toward Defining Matreotypes Promoting Healthy Aging.Gerontology. 2019 Dec 13;:1-9Authors: Ewald CYAbstract Accumulation of damage is generally considered the cause of aging. Interventions that delay aging mobilize mechanisms that protect and repair cellular components. Consequently, research…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:39

Prevalence of hypohydration and its association with stroke severity and independence outcomes in acute ischemic stroke patients.
Prevalence of hypohydration and its association with stroke severity and independence outcomes in acute ischemic stroke patients.: Related ArticlesPrevalence of hypohydration and its association with stroke severity and independence outcomes in acute ischemic stroke patients.J Clin Neurosci. 2019 Dec 11;:Authors: Buoite Stella A, Gaio M, Furlanis G, Ridolfi M, Ajčević M, Sartori A, Caruso P, Morrison SA, Naccarato M, Manganotti PAbstract Hypohydration has been suggested increasing the risk…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:38

Common Regulatory Targets of NFIA, NFIX and NFIB during Postnatal Cerebellar Development.
Common Regulatory Targets of NFIA, NFIX and NFIB during Postnatal Cerebellar Development.: Related ArticlesCommon Regulatory Targets of NFIA, NFIX and NFIB during Postnatal Cerebellar Development.Cerebellum. 2019 Dec 14;:Authors: Fraser J, Essebier A, Brown AS, Davila RA, Harkins D, Zalucki O, Shapiro LP, Penzes P, Wainwright BJ, Scott MP, Gronostajski RM, Bodén M, Piper M, Harvey TJAbstract Transcriptional regulation plays a central role in controlling neural stem and progenitor cell proliferation…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:38

Opsoclonus Following Downbeat Nystagmus in Absence of Visual Fixation in Multiple System Atrophy: Modulation and Mechanisms.
Opsoclonus Following Downbeat Nystagmus in Absence of Visual Fixation in Multiple System Atrophy: Modulation and Mechanisms.: Related ArticlesOpsoclonus Following Downbeat Nystagmus in Absence of Visual Fixation in Multiple System Atrophy: Modulation and Mechanisms.Cerebellum. 2019 Dec 14;:Authors: Lee JY, Kwon E, Kim HJ, Choi JY, Oh HJ, Kim JSAbstract We report atypical opsoclonus in a patient with multiple system atrophy and propose a mechanism based on the patterns of modulation by visual,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:38

Cells with ganglionic differentiation frequently stain for VE1 antibody: Mitogen-activated protein kinase (MAPK) pathway plays a major role in pediatric low-grade gliomas (pLGGs)
Cells with ganglionic differentiation frequently stain for VE1 antibody: a potential pitfall.: Related ArticlesCells with ganglionic differentiation frequently stain for VE1 antibody: a potential pitfall.Brain Tumor Pathol. 2019 Dec 09;:Authors: Tan CL, Lian DWQ, Kuick CH, Chan YH, Chang KTEAbstract Mitogen-activated protein kinase (MAPK) pathway plays a major role in pediatric low-grade gliomas (pLGGs). Immunohistochemistry with mutant-specific antibody, VE1, has appeared to be the most…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:38

Assessment of the contralateral facial artery pedicle nasolabial island flap for buccal defect repair
Assessment of the contralateral facial artery pedicle nasolabial island flap for buccal defect repair: Publication date: Available online 15 December 2019Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): X. Zhou, S.-E. Zhang, P. Nueangkhota, Y.-J. Liang, Y.-X. Su, G.-Q. LiaoAbstractThe facial artery pedicle nasolabial island flap (FAPNIF) is widely used for oral and maxillofacial reconstruction. However, its use in reconstruction after malignant tumour resection is limited…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:37

Directly repaired glass-ionomer cements
In vitro compressive strength and edge stability testing of directly repaired glass-ionomer cements: AbstractObjectiveTo study the repair potential of seven commercial glass-ionomer cements (GICs) using an in vitro edge compression test model.Materials and methodsA total of 448 normal and 192 repaired cylindrical specimens (6 × 4 mm) were produced from 6 GICs and one resin-modified GIC. Repaired samples consisted of a base aged for 1 month before repaired by an overlying layer. All samples were matured…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:36

Endoscopic transnasal transmaxillary approach to the upper parapharyngeal space and the skull base
Endoscopic transnasal transmaxillary approach to the upper parapharyngeal space and the skull base: AbstractPurposeTreatment of tumors arising in the upper parapharyngeal space (PPS) or the floor of the middle cranial fossa is challenging. This study aims to present anatomical landmarks for a combined endoscopic transnasal and anterior transmaxillary approach to the upper PPS and the floor of the middle cranial fossa and to further evaluate their clinical application.MethodsDissection of the upper…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:36

Feasibility of 3D printed salivary duct models for sialendoscopic skills training: preliminary report
Feasibility of 3D printed salivary duct models for sialendoscopic skills training: preliminary report: AbstractPurposesTo explore the feasibility of 3D printed salivary duct models for the sialendoscopic skills training.MethodsHealthy volunteers and patients affected by obstructive salivary gland disorders were submitted to 3 Tesla MR sialography. The MR data underwent an image segmentation process to produce the 3D printed salivary duct prototypes. Sialendoscopies were carried out by three groups…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:36

Hearing screenings for preschool children: A comparison between whispered voice and pure tone audiogram tests.
Hearing screenings for preschool children: A comparison between whispered voice and pure tone audiogram tests.: Related ArticlesHearing screenings for preschool children: A comparison between whispered voice and pure tone audiogram tests.Int J Pediatr Otorhinolaryngol. 2019 Nov 27;130:109798Authors: Skoloudik L, Mejzlik J, Janouch M, Drsata J, Vodicka J, Chrobok VAbstract INTRODUCTION: This prospective study compares the efficiency of two hearing screening tests performed on preschool children….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:36

Selenium improves photosynthesis
Selenium improves photosynthesis and induces ultrastructural changes but does not alleviate cadmium-stress damages in tomato plants: AbstractThe application of Se to plants growing under Cd contamination may become an alternative strategy to minimize Cd damage. However, there is no specific information available regarding whether Se can affect the anatomical structure and photosynthetic rates of plants under Cd stress. To address questions related to Se-protective responses under Cd stress, we evaluated…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:35

Is topical fluorescein that effective in endoscopic CSF leak closure?
Is topical fluorescein that effective in endoscopic CSF leak closure?: AbstractPurposeSeveral diagnostic modalities are used to detect CSF leaks. Intraoperative use of intrathecal fluorescein can help to detect and localize a CSF leak simultaneously. However, it is not FDA approved, the application is invasive and has serious complications. Topical fluorescein is reported to be a safe and sensitive alternative to ITF. In this study, we aimed to evaluate the effectiveness of topical fluorescein in…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:35

Patient-recorded benefit from nasal closure in a Danish cohort of patients with hereditary haemorrhagic telangiectasia
Patient-recorded benefit from nasal closure in a Danish cohort of patients with hereditary haemorrhagic telangiectasia: AbstractBackgroundNasal closure, also known as the modified Young’s procedure was introduced in Denmark in 2008, as a surgical solution to severe epistaxis in patients with hereditary haemorrhagic telangiectasia (HHT). The objective of this study was to report the overall satisfaction of the procedure from a patient’s point of view as well as the occurrence of complications.MethodsAll…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:35

A comparison of international clinical practice guidelines on adult chronic rhinosinusitis shows considerable variability of recommendations for diagnosis and treatment
A comparison of international clinical practice guidelines on adult chronic rhinosinusitis shows considerable variability of recommendations for diagnosis and treatment: AbstractObjectivesTo compare international clinical practice guidelines on adult chronic rhinosinusitis (CRS).DesignExtensive literature search in Embase, PubMed and the internet (Google, websites of well-known guideline organizations) on November 21st 2018.Main outcome measuresGuidelines’ quality was measured by the AGREE II instrument….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:35

Pre- and intraoperative acoustic and functional assessment of the novel APrevent ® VOIS implant during routine medialization thyroplasty
Pre- and intraoperative acoustic and functional assessment of the novel APrevent ® VOIS implant during routine medialization thyroplasty: AbstractPurposePersistent unilateral vocal fold paralysis (UFVP) with glottal insufficiency often requires type I medialization thyroplasty (MT). Previous implants cannot be adjusted postoperatively if necessary. The newly developed APrevent® VOIS implant (VOIS) can provide postoperative re-adjustment to avoid revision MT. The objective of this pilot study is to…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:34

Diagnosis and management of septal deviation and nasal valve collapse – a survey of Canadian otolaryngologists
Diagnosis and management of septal deviation and nasal valve collapse – a survey of Canadian otolaryngologists: AbstractBackgroundManagement of nasal valve collapse (NVC) in patients with a septal deviation can be challenging. Our objective was to determine the opinions of Canadian Otolaryngologists regarding the diagnosis and management of nasal obstruction in patients with septal deviation and NVC.MethodsA twenty-question survey was developed for the purpose of our study. Questions were divided…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:34

Intersegmenter Variability in High‐Speed Laryngoscopy‐Based Glottal Area Waveform Measures
Intersegmenter Variability in High‐Speed Laryngoscopy‐Based Glottal Area Waveform Measures: Objectives/HypothesisHigh‐speed videoendoscopy (HSV) has potential to objectively quantify vibratory vocal fold characteristics during phonation. Glottal Analysis Tools (GAT) version 2018, developed in Erlangen, Germany, is software for determining various glottal area waveform (GAW) quantities. Before having GAT analyze HSV videos, segmenters have to define glottis manually across videos in a semiautomatic…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:34

Manifestations of Skull Base IgG4‐Related Disease: 91% patients had isolated skull base masses without systemic disease. Cranial neuropathies were commonly observed in the abducens (45%), trigeminal (18%), and facial nerves (18%). Lesions frequently involved the cavernous sinus (55%; 6/11) with extension to the petroclival junction in 50% (3/6). Infiltration of the internal auditory canal was present in 27% (3/11) with one case demonstrating erosion of the bony labyrinth.
Manifestations of Skull Base IgG4‐Related Disease: A Multi‐Institutional Study: ObjectiveIgG4‐related disease (IgG4‐RD) is a recently recognized disease characterized by fibroinflammatory infiltrates rich in IgG4+ plasma cells that can present as isolated tumor‐like lesions of the head and neck. The objective of the current study was to describe the cranial base manifestations of IgG4‐RD.MethodsReview of all cases at three tertiary‐referral centers since disease description in 2003.ResultsEleven…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:34

Manifestations of Skull Base IgG4‐Related Disease: A Multi‐Institutional Study
Manifestations of Skull Base IgG4‐Related Disease: A Multi‐Institutional Study: ObjectiveIgG4‐related disease (IgG4‐RD) is a recently recognized disease characterized by fibroinflammatory infiltrates rich in IgG4+ plasma cells that can present as isolated tumor‐like lesions of the head and neck. The objective of the current study was to describe the cranial base manifestations of IgG4‐RD.MethodsReview of all cases at three tertiary‐referral centers since disease description in 2003.ResultsEleven…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:33

Endoscopic Nasopharyngectomy Combined with a Nerve‐sparing Transpterygoid Approach
Endoscopic Nasopharyngectomy Combined with a Nerve‐sparing Transpterygoid Approach: Objectives/HypothesisSurgical management of nasopharyngeal tumors has evolved in the endoscopic era. Lateral exposure remains difficult especially near the petrous internal carotid artery and bony Eustachian tube (ET). Our study examines the need to sacrifice the vidian and greater palatine nerves in order to successfully perform en bloc endoscopic nasopharyngectomy.MethodsFour cadaveric specimens (eight sides) were…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:33

Gallic acid affects blood-brain barrier permeability, behaviors, hippocampus local EEG, and brain oxidative stress in ischemic rats exposed to dusty particulate matter
Gallic acid affects blood-brain barrier permeability, behaviors, hippocampus local EEG, and brain oxidative stress in ischemic rats exposed to dusty particulate matter: AbstractDust storms are environmental natural events that transport high concentrations of particulate matter (PM) in living spaces. Recent epidemiological studies have shown that air pollution is associated with stroke. In the present study we aimed to investigate the probable protective effects of gallic acid (GA) on blood-brain…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:32

Ethnopharmacological Potentials of Warburgia ugandensis on Antimicrobial Activities
Ethnopharmacological Potentials of Warburgia ugandensis on Antimicrobial Activities: AbstractWarburgia ugandensis (W. ugandensis) is known by various names, including the East African greenheart, pepper bark tree, and Ugandan greenheart, and has a rich history of extensive use in the treatment of a host of human diseases in many African countries. This review is based on the botany and ethnopharmacological potentials of W. ugandensis for the treatment of pneumonia, asthma, malaria, candidiasis, skin…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:31

Key Genes and Signaling Pathways Associated with the Progression of Gastric Cancer
Identification of Key Genes and Signaling Pathways Associated with the Progression of Gastric Cancervia http://link.springer.com/search.rss?facet-content-type=Article&facet-journal-id=12253&channel-name=Pathology+%26+Oncology+ResearchAbstractGenomic features have been gradually regarded as part of the fundamentals to the clinical diagnosis and treatment for gastric cancer. However, the molecular alterations taking place during the progression of gastric cancer remain unclear. Therefore,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:30

Acta Parasitologica
Morphological and Molecular Characteristics of the Gastro-Intestinal Nematode Parasite Ascaridia columbae Infecting the Domestic Pigeon Columba livia domestica in Saudi ArabiaAbstractBackgroundParasitism is a complex problem that is often ignored in companion animals, including birds, unless it develops into a severe clinical disorder. The present study was, therefore, aimed to investigate the presence of the gastrointestinal nematode infecting the domestic pigeon and provide a complete morphological…

www Αλέξανδρος Γ. Σφακιανάκης

08:29

Medical Science Educator
Letter to the Editor on the Article: “Mixed Reality Anatomy Using Microsoft HoloLens and Cadaveric Dissection: a Comparative Effectiveness Study”Integration of Basic and Clinical Sciences: Student PerceptionsAbstractThe integrated curriculum is becoming a popular concept among dental schools. The purpose of this study was to query dental students at the University of Texas Health Science Center at Houston – School of Dentistry (UTSD) to elucidate their level of interest in the integrated curriculum,…

www Αλέξανδρος Γ. Σφακιανάκης

08:28

Current Dermatology Reports
Review of Outcome Measures in Trials and Practice for PsoriasisAbstractPurpose of ReviewThe purpose of this review was to determine the most frequently utilized outcome measures in clinical trials and to review the scoring criteria, advantages, disadvantages, and application in research and clinical settings, as well as provide an overview of the published guidelines on the use of outcome measures in clinical practice.Recent FindingsThe most frequently utilized physician-reported outcome measurement…

www Αλέξανδρος Γ. Σφακιανάκης

08:27

Nuclear Cardiology
Mitochondrial dysfunction in heart failure. Lessons from a hereditary mitochondrial diseaseThe voyage: Amalgating a social media platform through the annual scientific meetingAbstractSocial media platforms are increasingly used by professional societies for improved member engagement, to raise awareness, for advocacy and for widespread dissemination of scientific meeting highlights. This article describes the inaugural social media campaign implemented at the American Society of Nuclear Cardiology…

www Αλέξανδρος Γ. Σφακιανάκης

08:27

Advances in Health Sciences Education
The development of competency frameworks in healthcare professions: a scoping reviewAbstractCompetency frameworks serve various roles including outlining characteristics of a competent workforce, facilitating mobility, and analysing or assessing expertise. Given these roles and their relevance in the health professions, we sought to understand the methods and strategies used in the development of existing competency frameworks. We applied the Arksey and O’Malley framework to undertake this scoping…

www Αλέξανδρος Γ. Σφακιανάκης

08:26

Optometry and Vision Science
Giving ThanksNo abstract availableCorneal Endothelial Blebs Induced in Scleral Lens WearersSIGNIFICANCE In the bleb phenomenon, some endothelial cells transiently lose their specular reflection. This has been reported during contact lens wear and goggle-induced hypoxia or hypercapnia. PURPOSE The purposes of this study were to determine whether blebs appear after scleral lens wear and if their appearance is influenced by lens clearance and to compare bleb and cell sizes. METHODS Twenty-one subjects…

www Αλέξανδρος Γ. Σφακιανάκης

08:26

Translational Journal of the American College of Sports Medicine
Effects of Self-selected or Predetermined Intensity Aerobic Exercise on the Quality of Life of Adolescents with ObesityThis study aimed to compare the effects of aerobic training at self-selected intensity (SIE) and predetermined intensity (PIE) on the health-related quality of life (HRQOL) in adolescents with obesity. Randomized clinical trial conducted with 37 adolescents (boys and girls), 13–18 yr old, at Tanner stages 3–4, and body mass index ≥95th. Eighteen adolescents were randomly assigned…

www Αλέξανδρος Γ. Σφακιανάκης

08:25

The Back Letter
Award-Winning Study Highlights a Pivotal Question: Why is Disc Degeneration Sometimes Painful?No abstract availableDrive-by Billing CrisisNo abstract availableParalyzed Man Uses Brain Waves to Power an External SkeletonNo abstract availableNew Recommendations on Osteoporotic Fractures: Do Conflicts of Interest Impair Their Credibility?No abstract availableThe Burnout Crisis Demonstrates the Need for Broad Cultural Change in the Practice of MedicineNo abstract availableWhat About Coaching to Prevent…

www Αλέξανδρος Γ. Σφακιανάκης

08:24

Glaucoma
Surgical Outcomes and Quality Assessment of Trabeculectomy: Leveraging Electronic Health Records for Clinical Data VisualizationPrécis: This electronic medical record-based study demonstrates 1 approach to monitor clinical outcomes for individual physicians performing trabeculectomy. Purpose: The purpose of this study was to develop an interactive data visualization platform for evaluating trabeculectomy outcomes and monitoring clinical care quality. Patients and Methods: This is a retrospective…

www Αλέξανδρος Γ. Σφακιανάκης

08:24

Medicine
Effectiveness of acupuncture for the treatment of postoperative pain: A protocol for a systematic review of randomized controlled trialBackground: This aim of this study is to assess the effectiveness and safety of acupuncture for the treatment of patients with postoperative pain (PPP). Methods: We will carry out a systematic review of the published literature and will comprehensively search Cochrane Library, MEDLINE, EMBASE, CINAHL, PsycINFO, Allied and Complementary Medicine Database, Chinese Biomedical…

www Αλέξανδρος Γ. Σφακιανάκης

08:23

Clinical Engineering
A Winter’s TaleNo abstract availableKnee Replacement Patients May Enjoy Life-Changing Surgical Outcomes With RSIP Vision’s Revolutionary Artificial Intelligence SolutionNo abstract availableFood and Drug Administration Issues Important New GuidanceNo abstract availableInterpretation of Codes and StandardsNo abstract availableLigature Risk Management and Medical EquipmentNo abstract availableSeven Maryland and Virginia Municipalities Receive Grants For Policy and Environmental Changes that Promote…

www Αλέξανδρος Γ. Σφακιανάκης

08:22

Clinical Oncology
An Update to Changing Patterns of Anal Carcinoma in the United StatesObjectives: Approximately 8,300 new cases of anal carcinoma will be diagnosed in the United States in 2019. Anal squamous cell carcinoma (SCC) accounts for about 70% of all anal cancers. As cancer prevention and treatments have evolved over time, medical management of human immunodeficiency virus has improved, and sexual behaviors have changed, anal carcinoma incidence rates (IRs) may have also changed. Methods: The 9 oldest Surveillance,…

www Αλέξανδρος Γ. Σφακιανάκης

08:21

Ear Nose Throat
OnlineFirstLast updated December 16, 2019 1 – 100 of 371Sort:ClinicOpen AccessDouble Ring in Cochlear Otosclerosis: A Limit to Cochlear Implantation? The Solution Is the Surgical ApproachDaniela Messineo, MD, Massimo Ralli, MD, PhD, Antonio Greco, MD, Arianna Di Stadio, MD, PhDFirst Published 16 Dec 2019.https://doi.org/10.1177/0145561319895601AbstractHide PreviewWe present a case of a 50-year patient with a severe form of otosclerosis (double ring) that was successfully implanted. We used a bone-anchored…

www Αλέξανδρος Γ. Σφακιανάκης

08:21

Mammary Gland Biology and Neoplasia
Electron Tomography Revels that Milk Lipids Originate from Endoplasmic Reticulum Domains with Novel Structural FeaturesAbstractLipid droplets (LD) are dynamically-regulated organelles that originate from the endoplasmic reticulum (ER), and function in the storage, trafficking and metabolism of neutral lipids. In mammary epithelial cells (MEC) of lactating animals, intact LD are secreted intact into milk to form milk lipids by a novel apocrine mechanism. The secretion of intact LD and the relatively…

www Αλέξανδρος Γ. Σφακιανάκης

08:16

Historical Archaeology
Vital Data: Re/Introducing Historical BioarchaeologyColonialism, Community, and Heritage in Native New EnglandChallenging Colonial Narratives: Nineteenth-Century Great Lakes ArchaeologyWar at Sea: A Shipwrecked History from Antiquity to the Twentieth CenturySubmerged History: Underwater Archaeology in FloridaFramings of Capitalism and the Archaeology of Sugar in the Islamic MediterraneanAbstractSeeking to widen the constellation of pasts in studies of capitalism, this article contributes to interventions…

www Αλέξανδρος Γ. Σφακιανάκης

08:15

Otolaryngology
Original ResearchNo AccessPrevalence of Pediatric Dizziness and Imbalance in the United StatesJacob R. Brodsky, MD, Sophie Lipson, Neil Bhattacharyya, MDFirst Published 5 Nov 2019.https://doi.org/10.1177/0194599819887375AbstractHide PreviewObjectivesUnderstand the prevalence of vestibular symptoms in US children.Study DesignCross-sectional analysisSetting2016 National Health Interview Survey.Subjects and MethodsResponses from the 2016 National Health Interview Survey for children ages 3 to 17 years…

www Αλέξανδρος Γ. Σφακιανάκης

08:15

Otolaryngology
Original ResearchNo AccessPsychometric Evaluation of the Nasal Obstruction Symptom Evaluation Scale for Pediatric PatientsHena Din, MPH, Nour Bundogji, Shelby C. Leuin, MDFirst Published 10 Dec 2019.https://doi.org/10.1177/0194599819890835AbstractHide PreviewObjectiveTo evaluate the psychometric properties of the nasal obstruction symptom scale within a sample of pediatric patients undergoing septoplasty or functional septorhinoplasty.Study DesignThis was a prospective study with nasal obstruction…

www Αλέξανδρος Γ. Σφακιανάκης

08:14

Psychometric Evaluation of the Nasal Obstruction Symptom Evaluation Scale for Pediatric Patients
Hena Din, MPH, Nour Bundogji, Shelby C. Leuin, MDFirst Published 10 Dec 2019.https://doi.org/10.1177/0194599819890835AbstractHide PreviewObjectiveTo evaluate the psychometric properties of the nasal obstruction symptom scale within a sample of pediatric patients undergoing septoplasty or functional septorhinoplasty.Study DesignThis was a prospective study with nasal obstruction symptom scale evaluations conducted pre- and postoperatively.SettingA tertiary care pediatric hospital.Subjects and MethodsPediatric…

www Αλέξανδρος Γ. Σφακιανάκης

08:12

Ethics
Value-Enhancing Social Responsibility: Market Reaction to Donations by Family vs. Non-family Firms with Religious CEOsAbstractUsing a signaling framework, we argue that ethical behavior as evidenced by charitable donations is viewed more positively by investors when seen not to be based on self-serving motives but rather on authentic generosity that builds moral capital. The affirmed religiosity of CEOs may make their ethical position more credible, while their embeddedness within a family business…

www Αλέξανδρος Γ. Σφακιανάκης

08:11

Langenbeck’s Archives of Surgery
Holmium laser lithotripsy improves the rate of successful transcystic laparoscopic common bile duct explorationAbstractPurposeTranscystic laparoscopic common bile duct exploration (LCBDE) seems safer than transductal LCBDE and is associated with fewer biliary complications. It has traditionally been limited to smaller bile duct stones however. This study aimed to assess the ability of laser-assisted bile duct exploration by laparoendoscopy (LABEL) to increase the rate of successful transcystic LCBDE…

www Αλέξανδρος Γ. Σφακιανάκης

08:11

Archives of Pharmacal Research
Phytochemicals enriched in spices: a source of natural epigenetic therapyAbstractMetabolic disorders are increasing at an alarming rate due to the stressful lifestyle and inappropriate diet schedule. The unorganized habits influence multiple epigenetic mechanisms like DNA methylation, histone post-translational modifications and miRNA expression. These epigenetic modifications are reversible in nature and regulate gene expression in response to external stimuli without altering the DNA sequence….

www Αλέξανδρος Γ. Σφακιανάκης

08:10

Regenerative Engineering and Translational Medicine
Three-Dimensional Porous Trabecular Scaffold Exhibits Osteoconductive Behaviors In VitroAbstractIn the USA, approximately 500,000 bone grafting procedures are performed annually to treat injured or diseased bone. Autografts and allografts are the most common treatment options but can lead to adverse outcomes such as donor site morbidity and mechanical failure within 10 years. Due to this, tissue engineered replacements have emerged as a promising alternative to the biological options. In this study,…

www Αλέξανδρος Γ. Σφακιανάκης

08:09

Arab Journal of Gastroenterology
Endoscopic full-thickness resection for a duodenal gastrointestinal stromal tumourPublication date: Available online 6 December 2019Source: Arab Journal of GastroenterologyAuthor(s): Xiang-lei Yuan, Xiao-wei Liu, Bing HuDrug-induced pancreatitis: An updatePublication date: Available online 2 December 2019Source: Arab Journal of GastroenterologyAuthor(s): Jie Zheng, Qiu-Jin Yang, Fu-Tao Dang, Jing YangAbstractDrug-induced pancreatitis is a disease that is receiving increasing attention. This article…

www Αλέξανδρος Γ. Σφακιανάκης

08:09

Anaesthesia & Intensive Care Medicine
Therapeutic hypothermia and acute brain injuryPublication date: Available online 12 December 2019Source: Anaesthesia & Intensive Care MedicineAuthor(s): Jagdish Sokhi, Ugan ReddyAbstractSecondary brain injury has devastating effects on morbidity, mortality and good functional outcomes. Neuroprotection is multimodal, with decades of preclinical and small clinical studies showing the benefits of therapeutic hypothermia. The basic scientific principles have merit, yet large randomized controlled…

www Αλέξανδρος Γ. Σφακιανάκης

08:08

A&A Practice
Successful Verbal Communication Using Google Translate to Facilitate Awake Intubation of a Patient With a Language Barrier: A Case ReportPerioperative difficult airway management is one of the most challenging tasks encountered by anesthesiologists. Awake intubation is considered the gold standard in securing the anticipated difficult airway. Effective communication between the anesthesiologist and patient is vital during awake intubation. A language barrier can significantly hinder success and jeopardize…

www Αλέξανδρος Γ. Σφακιανάκης

08:08

Oral Oncology
select article Corrigendum to “Cutaneous keratinocyte cancers of the head and neck: Epidemiology, risk factors and clinical, dermoscopic and reflectance confocal microscopic features” [Oral Oncol. 98 (2019) 109–117] ErratumFull text access Corrigendum to “Cutaneous keratinocyte cancers of the head and neck: Epidemiology, risk factors and clinical, dermoscopic and reflectance confocal microscopic features” [Oral Oncol. 98 (2019) 109–117] Katie J. Lee, Mitchell Robinson, H. Peter SoyerIn Press, Corrected…

www Αλέξανδρος Γ. Σφακιανάκης

08:06

American Journal of Otolaryngology
select article Complications of bone-conduction hearing implants implantation surgeryResearch articleAbstract onlyComplications of bone-conduction hearing implants implantation surgeryTimothy Shun Man Chu, Michael Mather, Anirvan BanerjeeIn Press, Journal Pre-proof, Available online 16 December 2019Purchase PDFArticle previewAbstractAbstractPurposeBone-conduction Hearing Implants (BCHIs) are surgically implanted hearing devices. As the implantation surgery involves soft tissue dissection through…

www Αλέξανδρος Γ. Σφακιανάκης

08:05

Oral Oncology
Management of recurrent and metastatic oral cavity cancer: Raising the bar a step higherPublication date: February 2020Source: Oral Oncology, Volume 101Author(s): Petr Szturz, Jan B. VermorkenAbstractIn recurrent and/or metastatic squamous cell carcinoma of the head and neck (R/M-SCCHN), the armamentarium of systemic anti-cancer modalities continues to grow in parallel with innovations in and better integration of local approaches. The backbone of cytotoxic chemotherapy remains cisplatin with 5-fluorouracil…

www Αλέξανδρος Γ. Σφακιανάκης

08:03