Medicine by Alexandros G. Sfakianakis,

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
Arts, Vol. 9, Pages 56: “It’s All about Working with the Story!”: On Movement Direction in Musicals. An Interview with Lucy HindArts, Vol. 9, Pages 56: “It’s All about Working with the Story!”: On Movement Direction in Musicals. An Interview with Lucy Hind Arts doi: 10.3390/arts9020056 Authors: George Rodosthenous Lucy Hind is a South African choreographer and movement director who lives in the UK. Her training was in choreography, mime and physical theatre at Rhodes University, South Africa. After…

Αλέξανδρος Γ. Σφακιανάκης

09:46

,
Obesity in adolescent men increases the risk of venous thromboembolism in adult lifeAbstract Background As the population of obese and severely obese young adults grows, it is becoming increasingly important to recognize the long‐term risks associated with adolescent obesity. Objectives This study aimed to determine the association between body mass index (BMI) in young men at enlistment for military service and later risk of venous thromboembolism (VTE). Methods Nationwide register‐based prospective…

Αλέξανδρος Γ. Σφακιανάκης

09:44

,
Value of viscoelastic testing in detecting fibrinolysis and coagulopathy in malignancy‐associated coagulopathy and orthopaedic traumaANZ Journal of SurgeryMon Apr 27, 2020 19:22Issue information – TOCANZ Journal of SurgeryMon Apr 27, 2020 19:22Randomized controlled trials and Cochrane analyses versus precision‐based medicine for tranexamic acid and viscoelastic testing in traumaANZ Journal of SurgeryMon Apr 27, 2020 19:22Use of tranexamic acid in gastrointestinal bleeding and patients with haematological…

Αλέξανδρος Γ. Σφακιανάκης

09:44

,
Catalytic Asymmetric Iodoesterification of Simple AlkenesCatalytic asymmetric iodoesterification of simple alkenes was achieved using a dinuclear zinc‐3,3’‐( R , S , S )‐bis(aminoimino)binaphthoxide ( di‐Zn ) complex. For iodoesterification using p ‐methoxybenzoic acid, the N ‐iodonaphthalenimide (NIN)‐I 2 system was effective for producing iodoesters in a highly enantioselective manner. The synthetic utility of the optically active iodo‐ p ‐methoxybenzoate products was also demonstrated. The quartet…

Αλέξανδρος Γ. Σφακιανάκης

09:43

,
Powering Artificial Enzymatic Cascades with Electrical EnergyA bioelectrochemical flow system has been developed to power enzymatic cascades in vitro. H2 and O2 are generated by electrolysis and serve as electron mediators for oxidoreductases. Methylated N‐heterocycles were generated from diamines with up to 99 % product formation and a labeling regioselectivity of up to 99 %. Abstract We have developed a scalable platform that employs electrolysis for an in vitro synthetic enzymatic cascade in a…

Αλέξανδρος Γ. Σφακιανάκης

09:43

,
Superior cancer preventive efficacy of low versus high dose of mTOR inhibitor in a mouse model of prostate cancer.Related ArticlesSuperior cancer preventive efficacy of low versus high dose of mTOR inhibitor in a mouse model of prostate cancer. Oncotarget. 2020 Apr 14;11(15):1373-1387 Authors: Antoch MP, Wrobel M, Gillard B, Kuropatwinski KK, Toshkov I, Gleiberman AS, Karasik E, Moser MT, Foster BA, Andrianova EL, Chernova OV, Gudkov AV Abstract The mechanistic target of rapamycin (mTOR) is a PI3K-related…

Αλέξανδρος Γ. Σφακιανάκης

09:42

,
The Application of Radiomics in Breast MRI: A ReviewTechnology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Breast cancer has been a worldwide burden of women’s health. Although concerns have been raised for early diagnosis and timely treatment, the efforts are still needed for precision medicine and individualized treatment. Radiomics is a new technology with immense potential to obtain mineable data to provide rich information about the diagnosis and prognosis of…

Αλέξανδρος Γ. Σφακιανάκης

09:41

,
Increased Tissue Expression of Lectin-Like Oxidized LDL Receptor-1 (LOX-1) Is Associated with Disease Severity in Chronic Rhinosinusitis with Nasal Polyps.Related ArticlesIncreased Tissue Expression of Lectin-Like Oxidized LDL Receptor-1 (LOX-1) Is Associated with Disease Severity in Chronic Rhinosinusitis with Nasal Polyps. Diagnostics (Basel). 2020 Apr 23;10(4): Authors: Nishida M, Takeno S, Takemoto K, Takahara D, Hamamoto T, Ishino T, Kawasumi T Abstract BACKGROUND: The oxidative stress, induced…

Αλέξανδρος Γ. Σφακιανάκης

09:40

Glossopharyngeal Neuropathy / Neuralgia with Hemodynamic Instability and Associated Syncope Treated with Stereotactic Radiosurgery: Case Report.
Glossopharyngeal Neuropathy / Neuralgia with Hemodynamic Instability and Associated Syncope Treated with Stereotactic Radiosurgery: Case Report.: Related ArticlesGlossopharyngeal Neuropathy / Neuralgia with Hemodynamic Instability and Associated Syncope Treated with Stereotactic Radiosurgery: Case Report.World Neurosurg. 2020 Apr 25;:Authors: Banerjee C, Viers A, Vender JAbstract The incidence of glossopharyngeal neuralgia (GPN)/neuropathy (GPNo) is rare, with approximately 0.4-0.8 cases…

Αλέξανδρος Γ. Σφακιανάκης

09:39

Orbital Compartment Syndrome After Pterional Craniotomy for Removal of Meningioma of the Frontal Lobe Without Evidence of Orbital Mass or Ocular Compression: A Case Report and Literature Review.
Orbital Compartment Syndrome After Pterional Craniotomy for Removal of Meningioma of the Frontal Lobe Without Evidence of Orbital Mass or Ocular Compression: A Case Report and Literature Review.: Related ArticlesOrbital Compartment Syndrome After Pterional Craniotomy for Removal of Meningioma of the Frontal Lobe Without Evidence of Orbital Mass or Ocular Compression: A Case Report and Literature Review.World Neurosurg. 2020 Apr 25;:Authors: Dunford JM, Miller CAbstract A 76-year-old male…

Αλέξανδρος Γ. Σφακιανάκης

09:38

,
Nasal eosinophilic angiocentric fibrosis with IgG4-positive plasma cell infiltration.Related ArticlesNasal eosinophilic angiocentric fibrosis with IgG4-positive plasma cell infiltration. Malays J Pathol. 2020 Apr;42(1):137-141 Authors: Saenz-Ibarra B, Ceceñas-Falcon LA, Cardenas-De la Garza JA, Garza-Elizondo MA, De Hoyos R, Dieste M, Barboza-Quintana O Abstract INTRODUCTION: Eosinophilic angiocentric fibrosis (EAF) is a rare lesion that predominantly affects the upper respiratory tract. Its etiology…

Αλέξανδρος Γ. Σφακιανάκης

09:36

,
Purification, characterization and antioxidant activities in vitro of polysaccharides from Amaranthus hybridus L.Background Amaranthus hybridus L. is an annual, erect or less commonly ascending herb that is a member of the Amaranthaceae family. Polysaccharides extracted from traditional Chinese medicines may be effective substances with antioxidant activity. Methods In this study, we isolated crude polysaccharides from A. hybridus (AHP-M) using microwave-assisted extraction. Then, the AHP-M was purified…

Αλέξανδρος Γ. Σφακιανάκης

09:35

,
Adalimumab‐associated spondylodiscitis: a new or underestimated side effect?Wiley: Dermatologic Therapy: Table of ContentsTue Apr 28, 2020 14:54Retraction statement: Successful treatment of pyoderma gangrenosum with anakinra in a patient with Wiskott‐Aldrich SyndromeWiley: Dermatologic Therapy: Table of ContentsMon Apr 27, 2020 21:14Inflammatory features and rete ridge patterns of facial solar lentigo may guide laser treatmentAbstract Relatively little is known about the clinicopathologic characteristics…

Αλέξανδρος Γ. Σφακιανάκης

09:35

,
Evidence-Based Guidelines for Management of Head and Neck Mucosal Malignancies during the COVID-19 Pandemic.Related ArticlesEvidence-Based Guidelines for Management of Head and Neck Mucosal Malignancies during the COVID-19 Pandemic. Otolaryngol Head Neck Surg. 2020 Apr 28;:194599820923623 Authors: Crosby DL, Sharma A Abstract OBJECTIVE: Due to the current coronavirus disease 2019 (COVID-19) pandemic, otolaryngologists face novel challenges when treating patients with head and neck cancer. The purpose…

Αλέξανδρος Γ. Σφακιανάκης

09:34

,
Risk factors for lingual plate fracture during mandibular third molar extractionAbstract Objective The aim of this study was to predict the risk of lingual plate fracture during mandibular third molar (M3) extraction. Materials and methods Cone beam computed tomography (CBCT) data from 264 mandibular M3s (erupted and impacted) from 264 patients (104 males and 160 females; age range, 17–75 years) were retrospectively analyzed. Lingual…Clinical Oral Investigations03:00Mark above section as read pubmed:…

Αλέξανδρος Γ. Σφακιανάκης

09:33

,
The matriptase‐prostasin proteolytic cascade in dermatologic diseasesAbstract The proper development and function of skin and hair is dependent on proteolytic activities. Specifically, the matriptase‐prostasin cascade is a series of proteolytic reactions in the epidermis integral to normal regulation of desquamation. An increasing amount of research describing this pathway has recently become available, and the importance of this pathway is exhibited by the association of genetic defects in this…

Αλέξανδρος Γ. Σφακιανάκης

09:32

,
Pain-Induced Beta Activity in the Subthalamic Nucleus of Parkinson’s DiseaseBackground: The subthalamic nucleus (STN) is a common target for deep brain stimulation (DBS) in Parkinson’s disease (PD) and is believed to serve a role in sensorimotor integration. In addition to therapeutic neuromodulation, DBS facilitates the recording of local-field potentials (LFPs) in order to further understand the neurophysiological basis of disease. The capacity to wirelessly transmit these signals in real time…

Αλέξανδρος Γ. Σφακιανάκης

09:32

,
Evolution of COVID-19 Guidelines for University of Washington Oral and Maxillofacial Surgery Patient CarePublication date: Available online 28 April 2020Source: Journal of Oral and Maxillofacial SurgeryAuthor(s): Kanvar Panesar, Thomas Dodson, John Lynch, Chloe Bryson-Cahn, Lisa Chew, Jasjit DillonOral and Maxillofacial SurgeryWed Apr 29, 2020 17:47Clinical Application of Concentrated Growth Factor Fibrin Combined With Bone Repair Materials in Jaw DefectsPublication date: Available online 28 April…

Αλέξανδρος Γ. Σφακιανάκης

09:31

,
Metastatic HPV-Associated Oropharyngeal Versus Primary Pulmonary Squamous Cell Carcinoma: is p16 Immunostain Useful?Abstract The lungs are a common site of metastasis of head and neck (H&N) squamous cell carcinomas (SCC). This study attempts to define p16 immunoexpression and presence of HPV in primary SCC of the lung and determine their usefulness in discriminating between primary lung SCC and metastasis from HPV-associated oropharyngeal primary. Pathology archives were searched for patients…

Αλέξανδρος Γ. Σφακιανάκης

09:30

,
Combined 68Ga-DOTATOC and 18F-FDG PET Predicts a Double Component With Different Grade of a Pancreatic Neuroendocrine Tumor in a Patient With Multiple Endocrine Neoplasia Type 1Managing decisions of pancreatic neuroendocrine tumors (pNETs) can be challenging because of different clinical presentations and prognosis. A 31-year-old woman with multiple endocrine neoplasia type 1, including a suspicious pNET, was assessed with 68Ga-DOTATOC and 18F-FDG PET. A high 68Ga-DOTATOC uptake was visualized in…

Αλέξανδρος Γ. Σφακιανάκης

09:29

,
Reappraisal of Primary Epstein-Barr Virus (EBV)-positive Diffuse Large B-Cell Lymphoma of the Gastrointestinal Tract: Comparative Analysis Among Immunosuppressed and Nonimmunosuppressed Stage I and II-IV PatientsEpstein-Barr virus (EBV)-positive diffuse large B-cell lymphoproliferation encompasses a broad range of clinicopathologic findings, including specific subtypes, for example, EBV+ mucocutaneous ulcer. Here we reassessed 36 cases of primary EBV+ diffuse large B-cell lymphomas (16 men and 20…

Αλέξανδρος Γ. Σφακιανάκης

09:28

,
Corneal Neurotization: A Surgical Treatment for Neurotrophic KeratopathyNo abstract availableNorth American Neuro-Ophthalmology SocietyTue Apr 28, 2020 03:00Should a Hypercoagulable Workup Be Performed on Young Patients with Nonarteritic Anterior Ischemic Optic Neuropathy?: ResponseNo abstract availableNorth American Neuro-Ophthalmology SocietyTue Apr 28, 2020 03:00Mark above section as read Case Reports in PathologyNeuronal Differentiation in a Pituitary Macroadenoma with Focal Small Blue Round…

Αλέξανδρος Γ. Σφακιανάκης

09:27

,
The preservation of ancient DNA in archaeological fish bone [NEW RESULTS]The field of ancient DNA is taxonomically dominated by studies focusing on mammals. This taxonomic bias limits our understanding of endogenous DNA preservation for vertebrate taxa with different bone physiology, such as teleost fish. In contrast to most mammalian bone, teleost bone is typically brittle, porous, lightweight and is characterized by a lack of bone remodeling during growth. Using high-throughput shotgun sequencing,…

Αλέξανδρος Γ. Σφακιανάκης

09:26

,
Sino‐nasal outcome test–22: Cross‐cultural adaptation and validation in Russian speaking patientsLatest Issue of Clinical Otolaryngology RSS Feed06:50Hearing outcome after myringoplasty in Sweden: A nationwide registry‐based cohort studyLatest Issue of Clinical Otolaryngology RSS Feed06:50Expression of inhibitors of apoptosis proteins in salivary gland adenoid cystic carcinoma: XIAP is an independent marker of impaired cause‐specific survivalLatest Issue of Clinical Otolaryngology RSS Feed06:50Interspecialty…

Αλέξανδρος Γ. Σφακιανάκης

09:25

,
Current Treatment Options in OncologyPI3K Inhibitors and Their Role as Novel Agents for Targeted Therapy in LymphomaOpinion statement Phosphatidylinositol 3-kinase (PI3K) inhibitors represent a novel class of agents targeting the key cellular regulatory PI3K/AKT/mTOR pathway involved in crucial functions such as cellular proliferation, cell cycle regulation, protein synthesis, and cell motility. This review starts with an overview of the PI3K pathway and the rationale for its targeting in lymphoma…

Αλέξανδρος Γ. Σφακιανάκης

09:25

,
Oral radiation‐induced sarcomas: Systematic reviewAbstract Background The aim of this study was to integrate the available data published on radiation‐induced sarcoma of the oral cavity into an analysis of its clinical features, treatment modalities and prognostic factors. Methods An electronic search was undertaken in September 2019. The eligibility criteria included publications that had enough clinical and histological information to confirm the diagnosis. Results Forty‐two publications with 122…

Αλέξανδρος Γ. Σφακιανάκης

09:24

,
The roles of GRP81 as a metabolic sensor and inflammatory mediatorGPR81 (also named as HCA1) is a member of a subfamily of orphan G‐protein coupled receptors (GPCRs), coupled to Gi‐type G proteins. GPR81 was discovered in 2001 and identified as the only known endogenous receptor of lactate under physiological conditions in 2008, which opened a new field of research on how lactate may act as a signal molecule along with the GPR81 expression in roles of metabolic process and inflammatory response….

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:23

,
Definition of excessive daytime sleepiness in the general population: Feeling sleepy relates better to sleep-related symptoms and quality of life than the Epworth Sleepiness Scale score. Results from an epidemiological study.Related ArticlesDefinition of excessive daytime sleepiness in the general population: Feeling sleepy relates better to sleep-related symptoms and quality of life than the Epworth Sleepiness Scale score. Results from an epidemiological study. J Sleep Res. 2019 12;28(6):e12852…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:22

,
The microbial abundance dynamics of the paediatric oral cavity before and after sleep.Related ArticlesThe microbial abundance dynamics of the paediatric oral cavity before and after sleep. J Oral Microbiol. 2020;12(1):1741254 Authors: Carlson-Jones JAP, Kontos A, Kennedy D, Martin J, Lushington K, McKerral J, Paterson JS, Smith RJ, Dann LM, Speck P, Mitchell JG Abstract Objective: Microhabitats in the oral cavity differ in microbial taxonomy. However, abundance variations of bacterial and viral communities…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:21

,
Clinical and Histopathological Characteristics of Cutaneous Lymphoid Hyperplasia: A Comparative Study According to Causative Factors.Related ArticlesClinical and Histopathological Characteristics of Cutaneous Lymphoid Hyperplasia: A Comparative Study According to Causative Factors. J Clin Med. 2020 Apr 23;9(4): Authors: Choi ME, Lee KH, Lim DJ, Won CH, Chang SE, Lee MW, Choi JH, Lee WJ Abstract Cutaneous lymphoid hyperplasia (CLH) is a heterogeneous type of reactive lymphocytic infiltration resembling…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:20

,
AA pubmed: head and neckUpper respiratory tract sampling in COVID-19.Related ArticlesUpper respiratory tract sampling in COVID-19. Malays J Pathol. 2020 Apr;42(1):23-35 Authors: Mawaddah A, Gendeh HS, Lum SG, Marina MB Abstract INTRODUCTION: To review the present literature on upper respiratory tract sampling in COVID-19 and provide recommendations to improve healthcare practices and directions in future studies. METHODS: Twelve relevant manuscripts were sourced from a total of 7288 search results…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:19

,
Structural Correlates of the Sensorimotor Cerebellum in Parkinson’s Disease and Essential TremorAbstract Background Parkinson’s disease (PD) and essential tremor (ET) are commonly encountered movement disorders. Pathophysiologic processes that localize to the cerebellum are described in both. There are limited studies investigating cerebellar structural changes in these conditions, largely because of inherent challenges in the efficiency of segmentation. Methods We applied a novel multiatlas cerebellar…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:19

,
ScienceDirect Publication: Cell ReportsInhibition of Tumor VEGFR2 Induces Serine 897 EphA2-Dependent Tumor Cell Invasion and Metastasis in NSCLCPublication date: 28 April 2020Source: Cell Reports, Volume 31, Issue 4Author(s): Caroline Volz, Sara Breid, Carolin Selenz, Alina Zaplatina, Kristina Golfmann, Lydia Meder, Felix Dietlein, Sven Borchmann, Sampurna Chatterjee, Maike Siobal, Jakob Schöttle, Alexandra Florin, Mirjam Koker, Marieke Nill, Luka Ozretić, Niklas Uhlenbrock, Steven Smith, Reinhard…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:17

,
Ultrasound diagnosis of acute appendicitis complicating De Garengeot’s herniaAbstract De Garengeot’s hernia is a rare condition defined by the herniation of the vermiform appendix within a femoral hernia sac. We report a case of an 80-year-old woman admitted to our emergency department complaining of pain in the right groin. This symptomatology, present for 2 days, increased in the following 12 h. Ultrasonography (US) and contrast-enhanced computed tomography (CECT) were performed, which showed the…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:17

,
edoc: No conditions. Results ordered -Date Deposited.Perinatal mental disorders in Switzerland: prevalence estimates and use of mental-health servicesPerinatal mental disorders (PMDs) are the most common complication of pregnancy and the first postpartum year. Since PMD prevalence and use of mental-health services by perinatal women in Switzerland are unknown, we analysed existing health statistics.; We used statistics from a large health insurance company, hospitals and freelance midwives. We assessed…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:16

,
JAMA Online FirstVariation in COVID-19 Hospitalizations and Deaths Across New York City BoroughsThis study describes demographic characteristics and hospital bed capacities of the 5 New York City boroughs, and evaluates whether differences in testing for coronavirus disease 2019 (COVID-19), hospitalizations, and deaths have emerged as a signal of racial, ethnic, and financial disparities.JAMA Online First14hCommunity Use of Face Shields to Contain COVID-19This Viewpoint discusses the prospect that…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:14

,
Journal of Infection and ChemotherapyEarly prediction model of organ/space surgical site infection after elective gastrointestinal or hepatopancreatobiliary cancer surgeryPublication date: Available online 29 April 2020Source: Journal of Infection and ChemotherapyAuthor(s): Jun Okui, Ryo Ueno, Hiroki Matsui, Wataru Uegami, Hiroshi Hayashi, Toru Miyajima, Hiroshi KusanagiJournal of Infection and Chemotherapy12hΣήμανση της παραπάνω ενότητας ως αναγνωσμένης ScienceDirect Publication: International…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:13

,
A quasi-experiment on using guided mobile learning interventions in ESL classrooms: Time use and academic performanceAbstract This quasi-experimental study examined a guided learning approach towards the use of mobile devices and investigated the performance of language learners who were guided in the usage. A total of 419 students from two faculties were invited to participate in this 8-week intervention, 155 participants in the control group and 264 in the experimental group. In the experimental…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:12

,
FDA Approves Additional Recommended Dose of Pembrolizumab in AdultsThe FDA approved an additional recommended dose of 400 mg pembrolizumab (Keytruda) every 6 weeks across all adult indications. (Source: CancerNetwork)CancerNetwork18hHope Rugo, MD, on the Accelerated Approval of Sacituzumab Govitecan-hziyThe breast cancer expert discussed the implications of this approval, as well as the data that led to the approval of sacituzumab govitecan-hziy. (Source: CancerNetwork)CancerNetwork18hΣήμανση της…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:11

Αφαίρεση διαφημίσεων

,
ACS Nano: Latest Articles (ACS Publications)[ASAP] Immunological Responses Induced by Blood Protein Coronas on Two-Dimensional MoS₂ NanosheetsACS NanoDOI: 10.1021/acsnano.9b09744ACS Nano: Latest Articles (ACS Publications)9h[ASAP] A Heterojunction Structured WO_2.9-WSe₂ Nanoradiosensitizer Increases Local Tumor Ablation and Checkpoint Blockade Immunotherapy upon Low Radiation DoseACS NanoDOI: 10.1021/acsnano.9b08962ACS Nano: Latest…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:11

,
Iodide Transporters in the Endometrium: A Potential Diagnostic Marker for Women with Recurrent Pregnancy FailuresObjective: The element Iodine is an essential nutrient utilized by the thyroid glands, and deficiency of this element has been linked to reproductive failures. Iodide transporters are also present in reproductive tissues and cells of embryonic origin such as the endometrium and trophoblasts, respectively. The aim of this study is to understand if levels of iodide transporters are linked…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:10

,
A Survey on Frameworks Used for Robustness Analysis on Interdependent NetworksThe analysis of network robustness tackles the problem of studying how a complex network behaves under adverse scenarios, such as failures or attacks. In particular, the analysis of interdependent networks’ robustness focuses on the specific case of the robustness of interacting networks and their emerging behaviors. This survey systematically reviews literature of frameworks that analyze the robustness of interdependent…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:09

,
Hindawi Publishing CorporationDouble Effects of Environmental Regulation on Carbon Emissions in China: Empirical Research Based on Spatial Econometric ModelThis paper theoretically analyzes the direct impact of environmental regulation on carbon emissions and its indirect effects on carbon emissions through foreign direct investment (FDI), energy consumption, industrial structure, and technological innovation. Then, this paper constructs a spatial lag model to empirically test the dual effects of…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:08

,
Latest Results for CNS DrugsA Phase II Randomized Trial to Explore the Potential for Pharmacokinetic Drug–Drug Interactions with Stiripentol or Valproate when Combined with Cannabidiol in Patients with EpilepsyAbstract Background In recent randomized, placebo-controlled, phase III trials, highly purified cannabidiol demonstrated efficacy with an acceptable safety profile in patients with Lennox–Gastaut syndrome or Dravet syndrome. It is anticipated that antiepileptic drugs such as stiripentol and…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:07

,
Viruses, Vol. 12, Pages 497: The SARS-CoV-2 Exerts a Distinctive Strategy for Interacting with the ACE2 Human ReceptorViruses, Vol. 12, Pages 497: The SARS-CoV-2 Exerts a Distinctive Strategy for Interacting with the ACE2 Human Receptor Viruses doi: 10.3390/v12050497 Authors: Esther S. Brielle Dina Schneidman-Duhovny Michal Linial The COVID-19 disease has plagued over 200 countries with over three million cases and has resulted in over 200,000 deaths within 3 months. To gain insight into the high…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:06

,
Nanomaterials, Vol. 10, Pages 856: Hybrid Electro-Optical Pumping of Active Plasmonic NanostructuresNanomaterials, Vol. 10, Pages 856: Hybrid Electro-Optical Pumping of Active Plasmonic Nanostructures Nanomaterials doi: 10.3390/nano10050856 Authors: Andrey A. Vyshnevyy Dmitry Yu. Fedyanin Surface plasmon polaritons (SPPs) offer a unique opportunity to overcome the diffraction limit of light. However, this opportunity comes at the cost of the strong absorption of the SPP field in a metal, which unavoidably…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:05

,
Microorganisms, Vol. 8, Pages 648: Microbial Screening Based on the Mizoroki–Heck Reaction Permits Exploration of Hydroxyhexylitaconic-Acid-Producing Fungi in SoilsMicroorganisms, Vol. 8, Pages 648: Microbial Screening Based on the Mizoroki–Heck Reaction Permits Exploration of Hydroxyhexylitaconic-Acid-Producing Fungi in Soils Microorganisms doi: 10.3390/microorganisms8050648 Authors: Sano Yada Nomura Kusukawa Ando Matsumoto Wada Tanaka Ohara Aso Recently, we developed a unique microbial screening…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:04

,
International Journal of Molecular SciencesIJMS, Vol. 21, Pages 3148: Host BAG3 Is Degraded by Pseudorabies Virus pUL56 C-Terminal 181L-185L and Plays a Negative Regulation Role during Viral Lytic InfectionIJMS, Vol. 21, Pages 3148: Host BAG3 Is Degraded by Pseudorabies Virus pUL56 C-Terminal 181L-185L and Plays a Negative Regulation Role during Viral Lytic Infection International Journal of Molecular Sciences doi: 10.3390/ijms21093148 Authors: Chuang Lyu Wei-Dong Li Shu-Wen Wang Jin-Mei Peng Yong-Bo…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:02

,
Cancers, Vol. 12, Pages 1113: Stress Management: Death Receptor Signalling and Cross-Talks with the Unfolded Protein Response in CancerCancers, Vol. 12, Pages 1113: Stress Management: Death Receptor Signalling and Cross-Talks with the Unfolded Protein Response in Cancer Cancers doi: 10.3390/cancers12051113 Authors: Elodie Lafont Throughout tumour progression, tumour cells are exposed to various intense cellular stress conditions owing to intrinsic and extrinsic cues, to which some cells are remarkably…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:01

,
International Journal of Environmental Research and Public HealthIJERPH, Vol. 17, Pages 3114: Risk Perception and COVID-19IJERPH, Vol. 17, Pages 3114: Risk Perception and COVID-19 International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17093114 Authors: Liliana Cori Fabrizio Bianchi Ennio Cadum Carmen Anthonj The call for articles for the International Journal of Environmental Research and Public Health Special Issue “Research about risk perception in the Environmental…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:01

,
Antibiotics, Vol. 9, Pages 222: Quality of Life of Patients with Mandibular Third Molars and Mild Pericoronitis. A Comparison between Two Different Treatments: Extraction or Periodontal ApproachAntibiotics, Vol. 9, Pages 222: Quality of Life of Patients with Mandibular Third Molars and Mild Pericoronitis. A Comparison between Two Different Treatments: Extraction or Periodontal Approach Antibiotics doi: 10.3390/antibiotics9050222 Authors: Passarelli Lopez Desantis Piccirillo Rella Giovannini Speranza…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:00

#
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia,

Telephone consultation 11855 int 1193,

Medicine by Alexandros G. Sfakianakis,

Medicine by Alexandros G. Sfakianakis

,
Cancer ScienceMdm2 – open questionsAbstract The Mdm2 oncoprotein and its association with p53 were discovered 30 years ago, and a cornucopia of activities and regulatory pathways have been associated with it. In this review, we will raise questions about Mdm2 and its cousin Mdm4 that we consider worth pursuing in future research, reaching from molecular structures and intracellular activities all the way to development, evolution, and cancer therapy. We anticipate that such research will not only…

Medicine by Alexandros G. Sfakianakis

08:39

,
Ophthalmic Plastic & Reconstructive Surgery – Published Ahead-of-PrintEpithelial-Myoepithelial Carcinoma of the Lacrimal Gland: Case Report of Youngest PatientThe authors report a case of extremely uncommon malignancy of lacrimal gland epithelial-myoepithelial carcinoma. This carcinoma is more commonly encountered in salivary glands and comprises 1% of all salivary gland tumors. Its occurrence in the orbit is very rare with only 6 cases reported in the literature, most of which arose in a pleomorphic…

Medicine by Alexandros G. Sfakianakis

08:38

,
WHO South-East Asia Journal of Public Health : 2013 – 2(2)Turning commitments into actions: perspectives on emergency preparedness in South-East AsiaRoderico H Ofrin, Anil K Bhola, Nilesh BuddhaWHO South-East Asia Journal of Public Health 2020 9(1):5-14 Emergency preparedness is a continuous process in which risk and vulnerability assessments, planning and implementation, funding, partnerships and political commitment at all levels must be sustained and acted upon. It relates to health systems strengthening,…

Medicine by Alexandros G. Sfakianakis

08:38

,
Plastic and Reconstructive Surgery – Current IssueDocosahexaenoic Acid Improves Diabetic Wound Healing in a Rat Model by Restoring Impaired Plasticity of Macrophage Progenitor CellsBackground: Chronic inflammation associated with delayed diabetic wound healing is induced by disturbed polarization of macrophages derived mainly from predisposed progenitor cells in bone marrow. Docosahexaenoic acid plays a critical role in regulating the function of macrophage progenitor cells. The authors evaluated…

Medicine by Alexandros G. Sfakianakis

08:37

,
Latest Results for The Journal of Primary PreventionFood Insecurity and Housing Instability Partially Mediate the Association Between Maternal Depression and Child Problem BehaviorAbstract Maternal depression is a risk factor for the development of problem behavior in children. Although food insecurity and housing instability are associated with adult depression and child behavior, how these economic factors mediate or moderate the relationship between maternal depression and child problem behavior…

Medicine by Alexandros G. Sfakianakis

08:36

,
pubmed: philosophy for medic…Obesity as a barrier to kidney transplantation: Time to eliminate the body weight bias?Related ArticlesObesity as a barrier to kidney transplantation: Time to eliminate the body weight bias? Semin Dial. 2019 05;32(3):219-222 Authors: MacLaughlin HL, Campbell KL Abstract There is clear evidence that survival rates following transplantation far exceed those for remaining on dialysis, regardless of body size measured by body mass index (BMI). Studies over the past 15 years…

Medicine by Alexandros G. Sfakianakis

08:36

,
pubmed: philosophy for medic…Modelling towards a more holistic medicine: The Virtual Physiological Human (VPH).Related ArticlesModelling towards a more holistic medicine: The Virtual Physiological Human (VPH). Morphologie. 2019 Dec;103(343):127-130 Authors: Van Sint Jan S, Geris L Abstract The Virtual Physiological Human (VPH) is a European initiative, rooted in the international Physiome initiative, focusing on establishing a methodological and technological framework, enabling the collaborative…

Medicine by Alexandros G. Sfakianakis

08:35

,
pubmed: sleepChronotherapy for reduction of cardiovascular risk.Related ArticlesChronotherapy for reduction of cardiovascular risk. Med Clin (Barc). 2020 Apr 23;: Authors: Hermida RC, Hermida-Ayala RG, Smolensky M Abstract Numerous prospective studies establish that elevated asleep blood pressure (BP) constitutes a significant cardiovascular disease (CVD) risk factor, irrespective of daytime office BP measurements or awake and 24h BP measurements. Moreover, except for a small number of studies with…

Medicine by Alexandros G. Sfakianakis

08:34

,
pubmed: sleepAssociations of sleep duration and social jetlag with cardiometabolic risk factors in the study of Latino youth.Related ArticlesAssociations of sleep duration and social jetlag with cardiometabolic risk factors in the study of Latino youth. Sleep Health. 2020 Apr 22;: Authors: Johnson DA, Reid M, Vu TT, Gallo LC, Daviglus ML, Isasi CR, Redline S, Carnethon M Abstract OBJECTIVE: We investigated associations of sleep duration and social jetlag with cardiometabolic outcomes. PARTICIPANTS:…

Medicine by Alexandros G. Sfakianakis

08:34

,
AA pubmed: head and neckIntranasal Bolsters: A Novel Technique for Nasal Bone Stabilization.Related ArticlesIntranasal Bolsters: A Novel Technique for Nasal Bone Stabilization. J Craniofac Surg. 2020 Jan/Feb;31(1):e43-e45 Authors: Shokri T, Hilger PA, Lighthall JG Abstract Nasal bone stabilization, in the setting of comminuted nasal fracture or surgical osteotomy, represents a challenging surgical experience. Postoperative shifting of osseous fragments may result in compromised outcomes in an otherwise…

Medicine by Alexandros G. Sfakianakis

08:33

,
pubmed: sleepThe Impact of Common Psychiatric and Behavioral Comorbidities on Functional Disability Across Time and Individuals in Post-9/11 Veterans.Related ArticlesThe Impact of Common Psychiatric and Behavioral Comorbidities on Functional Disability Across Time and Individuals in Post-9/11 Veterans. J Trauma Stress. 2020 Apr 27;: Authors: Fortenbaugh FC, Fonda JR, Fortier CB, Amick MM, Milberg WP, McGlinchey RE Abstract Returning veterans often face multiple concurrent psychiatric and behavioral…

Medicine by Alexandros G. Sfakianakis

08:33

,
AA pubmed: head and neckOral Health Inequalities in 0-17-year-old Children Referred for Dental Extractions Under General Anaesthesia in Wolverhampton, 2013-2017.Related ArticlesOral Health Inequalities in 0-17-year-old Children Referred for Dental Extractions Under General Anaesthesia in Wolverhampton, 2013-2017. Community Dent Health. 2020 Apr 20;: Authors: Harper RS, Khan I, Chen R, Neville A Abstract OBJECTIVE: Describe the inequalities in oral health in children treated in a hospital located…

Medicine by Alexandros G. Sfakianakis

08:32

,
pubmed: health technologyA Tunable Extruded 3D Printing Platform using Thermo-Sensitive Pastes.Related ArticlesA Tunable Extruded 3D Printing Platform using Thermo-Sensitive Pastes. Int J Pharm. 2020 Apr 23;:119360 Authors: Yang Y, Wang X, Lin X, Xie L, Ivone R, Shen J, Yang G Abstract Extruded 3D printing is emerging as an attractive fabrication technology in the field of personalized oral medicines. The objective of this study was to develop a tunable extruded 3D printing platform based on thermo-sensitive…

Medicine by Alexandros G. Sfakianakis

08:31

,
Latest Results for Calcified Tissue InternationalDo Older Adults with Low Muscle Mass or Strength, in the Presence of Obesity, Have an Increased Risk of Joint Replacement Over 13 Years?Abstract This study aims to assess whether older adults with low muscle mass or strength, in the presence of obesity, have an increased risk of knee (TKR) and hip replacement (THR) over 13 years. 1082 community-dwelling older adults (51% women; mean age 62.9 ± 7.5 years) were studied at baseline and multiple time…

Medicine by Alexandros G. Sfakianakis

08:31

,
pubmed: health technologyNeuroenhancement in surgeons: benefits, risks and ethical dilemmas.Related ArticlesNeuroenhancement in surgeons: benefits, risks and ethical dilemmas. Br J Surg. 2020 Apr 26;: Authors: Patel R, Ashcroft J, Darzi A, Singh H, Leff DR Abstract BACKGROUND: Surgeons traditionally aim to reduce mistakes in healthcare through repeated training and advancement of surgical technology. Recently, performance-enhancing interventions such as neurostimulation are emerging which may offset…

Medicine by Alexandros G. Sfakianakis

08:30

,
JIN : Last 20 articlesCOVID-19: Possible Impact of the Genetic Background in <b><i>IFNL</i></b> Genes on Disease OutcomesJ Innate ImmunJIN : Last 20 articles15hΣήμανση της παραπάνω ενότητας ως αναγνωσμένης ScienceDirect Publication: International Journal of Biological MacromoleculesExtraction and biological activity of exopolysaccharide produced by <em>Leuconostoc mesenteroides</em> SN-8Publication date: 15 August 2020Source: International Journal of Biological…

Medicine by Alexandros G. Sfakianakis

08:29

,
CancersCancers, Vol. 12, Pages 1084: Multimodal Targeted Deep Sequencing of Circulating Tumor Cells and Matched Cell-Free DNA Provides a More Comprehensive Tool to Identify Therapeutic Targets in Metastatic Breast Cancer PatientsCancers, Vol. 12, Pages 1084: Multimodal Targeted Deep Sequencing of Circulating Tumor Cells and Matched Cell-Free DNA Provides a More Comprehensive Tool to Identify Therapeutic Targets in Metastatic Breast Cancer Patients Cancers doi: 10.3390/cancers12051084 Authors: Corinna…

Medicine by Alexandros G. Sfakianakis

08:29

,
Latest Results for Aesthetic Plastic SurgeryRisk and Reward: Public Perception of Gluteal Fat Grafting SafetyAbstract Background This study aims to understand how sociodemographic factors influence perceptions of “Brazilian Butt Lift” (BBL), the cosmetic procedure with the highest reported mortality rate, among adult women. We also investigate whether education about risks changes willingness to receive this procedure. Methods A Qualtrics© survey including education…Latest Results for Aesthetic…

Medicine by Alexandros G. Sfakianakis

08:28

,
Proceedings of the National Academy of Sciences current issueEvolution of male pregnancy associated with remodeling of canonical vertebrate immunity in seahorses and pipefishes [Evolution]A fundamental problem for the evolution of pregnancy, the most specialized form of parental investment among vertebrates, is the rejection of the nonself-embryo. Mammals achieve immunological tolerance by down-regulating both major histocompatibility complex pathways (MHC I and II). Although pregnancy has evolved…

Medicine by Alexandros G. Sfakianakis

08:27

,
Proceedings of the National Academy of Sciences current issueCorrection for Uyhazi et al., Pumilio proteins utilize distinct regulatory mechanisms to achieve complementary functions required for pluripotency and embryogenesis [Correction]DEVELOPMENTAL BIOLOGY Correction for “Pumilio proteins utilize distinct regulatory mechanisms to achieve complementary functions required for pluripotency and embryogenesis,” by Katherine E. Uyhazi, Yiying Yang, Na Liu, Hongying Qi, Xiao A. Huang, Winifred Mak,…

Medicine by Alexandros G. Sfakianakis

08:27

,
Αφαίρεση διαφημίσεων Free Radical Biology and MedicineDual role of oxidative stress-JNK activation in autophagy and apoptosis induced by nickel oxide nanoparticles in human cancer cellsPublication date: Available online 27 April 2020Source: Free Radical Biology and MedicineAuthor(s): Yik-Lam Cho, Hayden Weng Siong Tan, Quaiser Saquib, Yi Ren, Javed Ahmad, Rizwan Wahab, Weifeng He, Boon-Huat Bay, Han-Ming ShenFree Radical Biology and Medicine11hMicroRNA-based regulatory mechanisms underlying the synergistic…

Medicine by Alexandros G. Sfakianakis

08:26

,
PLOS Genetics: New ArticlesMutations in <i>SPATA13/ASEF2</i> cause primary angle closure glaucomaby Naushin H. Waseem, Sancy Low, Amna Z. Shah, Deepa Avisetti, Pia Ostergaard, Michael Simpson, Katarzyna A. Niemiec, Belen Martin-Martin, Hebah Aldehlawi, Saima Usman, Pak Sang Lee, Anthony P. Khawaja, Jonathan B. Ruddle, Ameet Shah, Ege Sackey, Alexander Day, Yuzhen Jiang, Geoff Swinfield, Ananth Viswanathan, Giovanna Alfano, Christina Chakarova, Heather J. Cordell, David F. Garway-Heath,…

Medicine by Alexandros G. Sfakianakis

08:25

,
Latest Results for Cellular and Molecular Life SciencesNoncoding RNAs in Duchenne and Becker muscular dystrophies: role in pathogenesis and future prognostic and therapeutic perspectivesAbstract Noncoding RNAs (ncRNAs), such as miRNAs and long noncoding RNAs, are key regulators of gene expression at the post-transcriptional level and represent promising therapeutic targets and biomarkers for several human diseases, including Duchenne and Becker muscular dystrophies (DMD/BMD). A role for ncRNAs in…

Medicine by Alexandros G. Sfakianakis

08:24

,
edoc: No conditions. Results ordered -Date Deposited.The 2018 ISHLT/APM/AST/ICCAC/STSW recommendations for the psychosocial evaluation of adult cardiothoracic transplant candidates and candidates for long-term mechanical circulatory supportThe psychosocial evaluation is well-recognized as an important component of the multifaceted assessment process to determine candidacy for heart transplantation, lung transplantation, and long-term mechanical circulatory support (MCS). However, there is no consensus-based…

Medicine by Alexandros G. Sfakianakis

08:24

,
Latest Results for EndocrineCOVID-19, hypothalamo-pituitary-adrenal axis and clinical implicationsLatest Results for Endocrine18hIdentification of gene co-expression modules and hub genes associated with the invasiveness of pituitary adenomaAbstract In pituitary adenoma (PA), invasiveness is the main cause of recurrence and poor prognosis. Thus, identifying specific biomarkers for diagnosis and effective treatment of invasive PAs is of great clinical significance. In this study, from the Gene Expression…

Medicine by Alexandros G. Sfakianakis

08:23

,
International Journal of Molecular SciencesIJMS, Vol. 21, Pages 3112: Involvement of Senescence and Mitochondrial Fission in Endothelial Cell Pro-Inflammatory Phenotype Induced by Angiotensin IIIJMS, Vol. 21, Pages 3112: Involvement of Senescence and Mitochondrial Fission in Endothelial Cell Pro-Inflammatory Phenotype Induced by Angiotensin II International Journal of Molecular Sciences doi: 10.3390/ijms21093112 Authors: Miyao Cicalese Kawai Cooper Boyer Elliott Forrester Kuroda Rizzo Hashimoto…

Medicine by Alexandros G. Sfakianakis

07:26

,
MicroorganismsMicroorganisms, Vol. 8, Pages 642: Temporal Dynamics of Bacterial Communities in a Pilot-Scale Vermireactor Fed with Distilled Grape MarcMicroorganisms, Vol. 8, Pages 642: Temporal Dynamics of Bacterial Communities in a Pilot-Scale Vermireactor Fed with Distilled Grape Marc Microorganisms doi: 10.3390/microorganisms8050642 Authors: María Gómez-Brandón Manuel Aira Natielo Santana Marcos Pérez-Losada Jorge Domínguez Vermicomposting has been found as a profitable approach to dispose of…

Medicine by Alexandros G. Sfakianakis

07:26

,
Cancers, Vol. 12, Pages 1091: The Circular RNA Landscape of Non-Small Cell Lung Cancer CellsCancers, Vol. 12, Pages 1091: The Circular RNA Landscape of Non-Small Cell Lung Cancer Cells Cancers doi: 10.3390/cancers12051091 Authors: Nele Van Der Steen Yanhong Lyu Anne K. Hitzler Andrea C. Becker Jeanette Seiler Sven Diederichs The class of circular RNA (circRNA) is characterized by head-to-tail bonds between exons formed by backsplicing. Here, we provide a resource of circRNA expression in a comprehensive…

Medicine by Alexandros G. Sfakianakis

07:25

,
International Journal of Environmental Research and Public HealthIJERPH, Vol. 17, Pages 3071: An Inventory of European Birth CohortsIJERPH, Vol. 17, Pages 3071: An Inventory of European Birth Cohorts International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17093071 Authors: Pansieri Pandolfini Clavenna Choonara Bonati Many birth cohorts have been carried out. We performed a review of European birth cohorts to see the countries involved, provide a panorama of the current…

Medicine by Alexandros G. Sfakianakis

07:25

,
Antibiotics, Vol. 9, Pages 215: Prevalence and Antimicrobial Susceptibility Patterns of Bacterial Pathogens in Urinary Tract Infections in University Hospital of Campania “Luigi Vanvitelli” between 2017 and 2018Antibiotics, Vol. 9, Pages 215: Prevalence and Antimicrobial Susceptibility Patterns of Bacterial Pathogens in Urinary Tract Infections in University Hospital of Campania “Luigi Vanvitelli” between 2017 and 2018 Antibiotics doi: 10.3390/antibiotics9050215 Authors: Folliero Caputo Rocca Chianese…

Medicine by Alexandros G. Sfakianakis

07:24

Cerebral venous sinus thrombosis following transsphenoidal surgery for craniopharyngioma: A case report.
Cerebral venous sinus thrombosis following transsphenoidal surgery for craniopharyngioma: A case report.: Related ArticlesCerebral venous sinus thrombosis following transsphenoidal surgery for craniopharyngioma: A case report.World J Clin Cases. 2020 Mar 26;8(6):1158-1163Authors: Chang T, Yang YL, Gao L, Li LHAbstract BACKGROUND: Cerebral venous sinus thrombosis (CVST) is a rare condition in patients with craniopharyngioma following transsphenoidal surgery. CASE SUMMARY: A 56-year-old…

Medicine by Alexandros G. Sfakianakis

07:23

Hyoid-complex elevation and stimulation technique restores swallowing function in patients with lateral medullary syndrome: Two case reports.
Hyoid-complex elevation and stimulation technique restores swallowing function in patients with lateral medullary syndrome: Two case reports.: Related ArticlesHyoid-complex elevation and stimulation technique restores swallowing function in patients with lateral medullary syndrome: Two case reports.World J Clin Cases. 2020 Mar 26;8(6):1142-1149Authors: Jiang YE, Lyu QQ, Lin F, You XT, Jiang ZLAbstract BACKGROUND: A swallowing disorder may occur following a brainstem stroke, especially one…

Medicine by Alexandros G. Sfakianakis

07:23

Scaphoid metastasis as the first sign of occult gastroesophageal junction cancer: A case report.
Scaphoid metastasis as the first sign of occult gastroesophageal junction cancer: A case report.: Related ArticlesScaphoid metastasis as the first sign of occult gastroesophageal junction cancer: A case report.World J Clin Cases. 2020 Apr 06;8(7):1287-1294Authors: Zhang YJ, Wang YY, Yang Q, Li JBAbstract BACKGROUND: Metastatic tumors of the hand are very rare. They are usually late manifestations of massive advanced malignancies. However, a small portion of acrometastases are indications…

Medicine by Alexandros G. Sfakianakis

07:22

Atypical presentation of SARS-CoV-2 infection: A case report.
Atypical presentation of SARS-CoV-2 infection: A case report.: Related ArticlesAtypical presentation of SARS-CoV-2 infection: A case report.World J Clin Cases. 2020 Apr 06;8(7):1265-1270Authors: Li RL, Chu SG, Luo Y, Huang ZH, Hao Y, Fan CHAbstract BACKGROUND: The first case of pneumonia subsequently attributed to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) occurred in Wuhan, Hubei Province on December 8, 2019. The symptoms included fever, coughing, and breathing difficulties….

Medicine by Alexandros G. Sfakianakis

07:22

,
Systemic treatment for severe concentrated sulfuric acid burns in an adult male at high altitude: A case report.Related ArticlesSystemic treatment for severe concentrated sulfuric acid burns in an adult male at high altitude: A case report. World J Clin Cases. 2020 Apr 06;8(7):1337-1342 Authors: Zhao RM, Li Y, Chao SW, Wang HJ Abstract BACKGROUND: The aim of this study was to report a case of a patient who suffered from severe concentrated sulfuric acid burns while working at high altitude. This…

Medicine by Alexandros G. Sfakianakis

07:21

Multiple neurofibromas plus fibrosarcoma with familial NF1 pathogenicity: A case report.
Multiple neurofibromas plus fibrosarcoma with familial NF1 pathogenicity: A case report.: Related ArticlesMultiple neurofibromas plus fibrosarcoma with familial NF1 pathogenicity: A case report.World J Clin Cases. 2020 Apr 06;8(7):1306-1310Authors: Wang Y, Lu XF, Chen LL, Zhang YW, Zhang BAbstract BACKGROUND: Neurofibromatosis (NF) is a genetic disease consisting of seven types, of which types 1 to 4 are caused by a dominant autosomal gene mutation; such disease sometimes arises in patients…

Medicine by Alexandros G. Sfakianakis

07:21

Σήμανση της παραπάνω ενότητας ως αναγνωσμένης

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

Αφαίρεση διαφημίσεων

Αφαίρεση διαφημίσεων


,
Head & Face Medicine – Latest ArticlesEvaluation of the relationship between malar projection and lower facial convexity in terms of perceived attractiveness in 3-dimensional reconstructed imagesThis study aimed to investigate dental student’s perception of facial attractiveness with regard to different combinations of anteroposterior malar-jaw positions using 3-dimensional (3-D) reconstructed images …Head & Face Medicine – Latest Articles5hΣήμανση της παραπάνω ενότητας ως αναγνωσμένης American…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:23

,
Cancer Research Online First ArticlesDe novo lipogenesis alters the phospholipidome of esophageal adenocarcinomaThe incidence of esophageal adenocarcinoma is rising, survival remains poor, and new tools to improve early diagnosis and precise treatment are needed. Cancer phospholipidomes quantified with mass spectrometry imaging can support objective diagnosis in minutes using a routine frozen tissue section. However, whether mass spectrometry imaging can objectively identify primary esophageal adenocarcinoma…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:22

,
Applying the New Guidelines of HER2 Testing in Breast CancerAbstract Purpose of Review The human epidermal growth factor receptor 2 (HER2) is an important prognostic and predictive biomarker in the breast cancer. The American Society of Clinical Oncology/College of American Pathology (ASCO/CAP) has published HER2 testing guidelines in breast cancer. We herein reviewed the HER2 testing guidelines in breast cancer with a focus on the application of the current guidelines. …Latest Results2hΣήμανση…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:21

,
JBC Papers in PressThe two paralogous kiwellin proteins KWL1 and KWL1-b from maize are structurally related and have overlapping functions in plant defense [Plant Biology]Many plant-pathogenic bacteria and fungi deploy effector proteins that down-regulate plant defense responses and reprogram plant metabolism for colonization and survival in planta. Kiwellin (KWL) proteins are a widespread family of plant-defense proteins that target these microbial effectors. The KWL1 protein from maize (corn,…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:21

Associations of telomerase reverse transcriptase rs10069690 and rs2736100 polymorphisms with papillary thyroid carcinoma
Associations of telomerase reverse transcriptase rs10069690 and rs2736100 polymorphisms with papillary thyroid carcinoma: Papillary thyroid carcinoma is one of the most common endocrine malignancies. Telomerase reverse transcriptase rs10069690 and rs2736100 polymorphisms have been studied in thyroid carcinomas with different ethnicity, but the results were inconsistent. Therefore, we evaluated the relationship between rs10069690 and rs2736100 polymorphisms and papillary thyroid carcinoma risk and…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:20

Duodenal neoplasms of gastric phenotype: reports of two cases and a brief review of literature
Duodenal neoplasms of gastric phenotype: reports of two cases and a brief review of literature: Duodenal neoplasms of gastric phenotype are uncommon epithelial neoplasms. Pyloric gland adenomas should be recognized as neoplasms with risk for transformation into invasive adenocarcinoma (Choi et al. 2018). Here we report the case histories of two male patients, who presented with duodenal polypoid lesion. Endoscopic polypectomy and endoscopic submucosal dissection were carried out, respectively. Histopathologically,…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:20

β-Defensin Strengthens Antimicrobial Peritoneal Mast Cell Response
β-Defensin Strengthens Antimicrobial Peritoneal Mast Cell Response: Mast cells (MCs) are engaged in the processes of host defense, primarily via the presence of receptors responsible for the detection of pathogen-associated molecular patterns (PAMPs). Since BDs are exclusively host defense molecules, and MCs can elicit the antimicrobial response, this study is aimed at determining whether BDs might be involved in MC pathogen defense. We found that defensin BD-2 significantly augments the mRNA and…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:19

Rare Somatic MEN1 Gene Pathogenic Variant in a Patient Affected by Atypical Parathyroid Adenoma
Rare Somatic MEN1 Gene Pathogenic Variant in a Patient Affected by Atypical Parathyroid Adenoma: Objective. Atypical parathyroid adenoma is a rare neoplasm, showing atypical histological features intermediate between classic benign adenoma and the rarest parathyroid carcinoma, whose the clinical behaviour and outcome is not yet understood or predictable. Up to date only two cases of atypical adenoma were found associated to a MEN1 syndrome, and only one was proved to carry a pathogenic variant of…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:18

Evaluation of Changes in Macular Perfusion Detected by Optical Coherence Tomography Angiography following 3 Intravitreal Monthly Bevacizumab Injections for Diabetic Macular Edema in the IMPACT Study
Evaluation of Changes in Macular Perfusion Detected by Optical Coherence Tomography Angiography following 3 Intravitreal Monthly Bevacizumab Injections for Diabetic Macular Edema in the IMPACT Study: Objective. To evaluate macular perfusion changes following intravitreal bevacizumab injections for diabetic macular edema (DME) using spectral domain optical coherence tomography angiography (SD-OCTA). Methods. This study was a prospective noncomparative interventional case series. Treatment naïve patients…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:18

Distinguishing Kawasaki Disease from Febrile Infectious Disease Using Gene Pair Signatures
Distinguishing Kawasaki Disease from Febrile Infectious Disease Using Gene Pair Signatures: Kawasaki disease (KD) is an acute systemic vasculitis of childhood with prolonged fever, and the diagnosis of KD is mainly based on clinical criteria, which is prone to misdiagnosis with other febrile infectious (FI) diseases. Currently, there remain no effective molecular markers for KD diagnosis. In this study, we aimed to use a relative-expression-based method k-TSP and resampling framework to identify…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:15

Effect of Quercetin on PC12 Alzheimer’s Disease Cell Model Induced by Aβ25-35 and Its Mechanism Based on Sirtuin1/Nrf2/HO-1 Pathway
Effect of Quercetin on PC12 Alzheimer’s Disease Cell Model Induced by Aβ25-35 and Its Mechanism Based on Sirtuin1/Nrf2/HO-1 Pathway: Objective. This study is aimed at studying the effect of quercetin on the Alzheimer disease cell model induced by Aβ25-35 in PC12 cells and its mechanism of action. Methods. The AD cell model was established by Aβ25-35. Quercetin was used at different concentrations (0, 10, 20, 40, and 80 μmol/L). The morphology of cells was observed, and the effect on cell survival…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:14

Efficacy and Safety of Lamivudine or Telbivudine in Preventing Mother-to-Child Transmission of Hepatitis B Virus: A Real-World Study
Efficacy and Safety of Lamivudine or Telbivudine in Preventing Mother-to-Child Transmission of Hepatitis B Virus: A Real-World Study: Background. There are few large sample studies evaluating the safety and efficacy of lamivudine (LAM) or telbivudine (LdT) in preventing hepatitis B mother-to-child transmission (MTCT) in highly viremic mothers in the third trimester of pregnancy in real-world settings. The purpose of this study was to analyze a large sample size of HBV-infected mothers to better understand…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:14

Comparative Lipid-Lowering/Increasing Efficacy of 7 Statins in Patients with Dyslipidemia, Cardiovascular Diseases, or Diabetes Mellitus: Systematic Review and Network Meta-Analyses of 50 Randomized Controlled Trials………………The statins included simvastatin (SIM), fluvastatin (FLU), atorvastatin (ATO), rosuvastatin (ROS), lovastatin (LOV), pravastatin (PRA), and pitavastatin (PIT). In terms of LDL-C lowering, rosuvastatin ranked 1st…………………………….rosuvastatin ranked 1st in LDL-C, ApoB-lowering efficacy and ApoA1-increasing efficacy. Lovastatin ranked 1st in TC- and TG-lowering efficacy, and fluvastatin ranked 1st in HDL-C-increasing efficacy
Comparative Lipid-Lowering/Increasing Efficacy of 7 Statins in Patients with Dyslipidemia, Cardiovascular Diseases, or Diabetes Mellitus: Systematic Review and Network Meta-Analyses of 50 Randomized Controlled Trials: Objective. The drug efficacy may differ among different statins, and evidence from head-to-head comparisons is sparse and inconsistent. The study is aimed at comparing the lipid-lowering/increasing effects of 7 different statins in patients with dyslipidemia, cardiovascular diseases,…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:13

Left Ventricular Ejection Fraction Is Associated with the Risk of Thrombus in the Left Atrial Appendage in Patients with Atrial Fibrillation
Left Ventricular Ejection Fraction Is Associated with the Risk of Thrombus in the Left Atrial Appendage in Patients with Atrial Fibrillation: Introduction. Atrial fibrillation (AF) is associated with high risk of ischemic stroke. The most frequent thrombus location in AF is the left atrial appendage (LAA). Transthoracic echocardiography (TTE) is a basic diagnostic examination in patients (pts) with AF. Objectives. To analyse the relations between basic echocardiographic features, well-established…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:11

Thumb Interphalangeal Joint Replacement as an Alternative to Joint Fusion
Thumb Interphalangeal Joint Replacement as an Alternative to Joint Fusion: Arthrodesis is the generally accepted treatment for symptomatic osteoarthritis of the interphalangeal (IP) joint of the thumb. For 7 thumbs in 5 patients, an IP joint replacement was offered as a pain alleviating and motion conserving treatment option for osteoarthritis. In these cases, an offlabel use of the SR-PIP prosthesis was performed. All patients did well postoperatively with reasonable pain-free range of motion of…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:11

The Diagnostic Yields and Safety of Double-Balloon Enteroscopy in Obscure Gastrointestinal Bleeding and Incomplete Small Bowel Obstruction: Comparison between the Adults and Elderly
The Diagnostic Yields and Safety of Double-Balloon Enteroscopy in Obscure Gastrointestinal Bleeding and Incomplete Small Bowel Obstruction: Comparison between the Adults and Elderly: Background. Double-balloon enteroscopy (DBE) is widely used worldwide. However, comparisons between the diagnostic yields in adults and the elderly remain scarce. Aim. The aim of this study is to compare the diagnostic yields and safety of DBE between adults and elderly with obscure gastrointestinal bleeding and incomplete…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:10

High Expression of Both Resistin and Fascin-1 Predicts a Poor Prognosis in Patients with Colorectal Cancer
High Expression of Both Resistin and Fascin-1 Predicts a Poor Prognosis in Patients with Colorectal Cancer: Emerging evidence indicates that resistin and fascin-1 may possess a causal role in the development of several types of cancers. However, the clinical significance of resistin expression in colorectal cancer (CRC) tissues is unclear, and there are no reports of any correlation between resistin and fascin-1. Our analyses explored the expression of resistin in CRC tissue and analyzed the clinical…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:09

99mTc-CXCR4-L for Imaging of the Chemokine-4 Receptor Associated with Brain Tumor Invasiveness: Biokinetics, Radiation Dosimetry, and Proof of Concept in Humans
99mTc-CXCR4-L for Imaging of the Chemokine-4 Receptor Associated with Brain Tumor Invasiveness: Biokinetics, Radiation Dosimetry, and Proof of Concept in Humans: Overexpression of the chemokine-4 receptor (CXCR4) in brain tumors is associated with high cancer cell invasiveness. Recently, we reported the preclinical evaluation of 99mTc-CXCR4-L (cyclo-D-Tyr-D-[NMe]Orn[EDDA-99mTc-6-hydrazinylnicotinyl]-Arg-NaI-Gly) as a SPECT radioligand capable of specifically detecting the CXCR4 protein. This research…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:09

Αφαίρεση διαφημίσεων


The Efficacy of Pegylated Liposomal Doxorubicin-Based Neoadjuvant Chemotherapy in Breast Cancer
The Efficacy of Pegylated Liposomal Doxorubicin-Based Neoadjuvant Chemotherapy in Breast Cancer: A Retrospective Case-Control Study in Taiwan: Breast cancer is a global issue regarding women’s health, and high incident rates remain in the Taiwanese female population. Chemotherapy, using anthracycline-based chemotherapeutic agents in neoadjuvant settings, has been introduced as a promising new therapeutic option for treatment of invasive breast cancer. Set apart from conventional anthracycline regimens…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:07

Host ESCRT factors are recruited during Chikungunya virus infection and are required the intracellular viral replication cycle [Cell Biology]
Host ESCRT factors are recruited during Chikungunya virus infection and are required the intracellular viral replication cycle [Cell Biology]: Chikungunya fever (CHIKF) is a re-emerging zoonotic disease caused by Chikungunya virus (CHIKV), a member of the alphavirus genus in the Togaviridae family. Only a few studies have reported on the host factors required for intracellular CHIKV trafficking. Here, we conducted an imaging-based small interfering RNA (siRNA) screen to identify human host factors…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:07

Elobixibat for the Elderly with Chronic Constipation
The Efficacy and Safety of Elobixibat for the Elderly with Chronic Constipation: A Multicenter Retrospective Cohort Study: Backgrounds and Aims. Elobixibat is a bile acid transporter inhibitor indicated for constipation. Previous studies were performed mainly for the nonelderly and were biased to female. We analyzed the efficacy of elobixibat also for the elderly and male. Materials and Methods. This was a multicenter retrospective cohort study. The subjects were patients aged ≥20 years treated for…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:06

Impacts of Outdoor Air Pollution on Human Semen Quality
Impacts of Outdoor Air Pollution on Human Semen Quality: A Meta-Analysis and Systematic Review: Introduction. Several studies have explored the association between outdoor air pollution and semen quality. However, the results were inconsistent. We performed the current meta-analysis to evaluate the role of outdoor air pollution in semen quality. Material and Methods. Databases including PubMed, Web of Science, and Embase were searched to identify relevant studies. Relative data in participants under…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:05

ARDS and Massive Pulmonary Embolism: The Combined Use of Extracorporeal Membrane Oxygenation (ECMO) with Thrombolytics
ARDS and Massive Pulmonary Embolism: The Combined Use of Extracorporeal Membrane Oxygenation (ECMO) with Thrombolytics: Pancreatitis causes a systemic inflammatory response that can lead to acute respiratory distress syndrome (ARDS). We present a case of severe ARDS complicated by a pulmonary embolism (PE) in a 39-year-old female that developed rapidly progressive pancreatitis secondary to hypertriglyceridemia.

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:05

Fatal Methanol Poisoning Caused by Drinking Adulterated Locally Distilled Alcohol
Fatal Methanol Poisoning Caused by Drinking Adulterated Locally Distilled Alcohol: Wakiso District, Uganda, June 2017: Background. Methanol, an industrial solvent, can cause illness and death if ingested. In June 2017, the Uganda Ministry of Health was notified of a cluster of deaths which occurred after drinking alcohol. We investigated to determine the cause of outbreak, identify risk factors, and recommend evidence-based control measures. Methods. We defined a probable case as acute loss of eyesight…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:05

Methotrexate-Associated Lymphoproliferative Disorder Developed Ectopically in the Maxillary Gingiva and Bilateral Lungs
Methotrexate-Associated Lymphoproliferative Disorder Developed Ectopically in the Maxillary Gingiva and Bilateral Lungs: A 58-year-old Japanese woman complained of a painful right maxillary premolar gingiva and ulcer. The patient had RA and had been treated with several immunosuppressive drugs such as methotrexate. Head and neck CT indicated no obvious bone destruction with maxillary. However, chest CT indicated the presence of nodular mass of the bilateral lungs. FDG-PET/CT indicated the presence…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:03

Lipoprotein Particle Predictors of Arterial Stiffness
Lipoprotein Particle Predictors of Arterial Stiffness after 17 Years of Follow Up: The Malmö Diet and Cancer Study: Background. Central arterial stiffness is a surrogate of cardiovascular risk and predicts cardiovascular mortality. Apolipoprotein B lipoproteins are also established cardiovascular risk factors. It is not known whether specific lipoprotein subclasses measured in the Malmö Diet and Cancer Study and previously shown to be associated with coronary heart disease also predict arterial stiffening…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:02

Fibrinogen as a Prognostic Predictor in Pediatric Patients with Sepsis: A Database Study
Fibrinogen as a Prognostic Predictor in Pediatric Patients with Sepsis: A Database Study: Background. Systemic inflammatory response and vascular endothelial cell injury during sepsis lead to coagulopathy. Fibrinogen has been reported as a biomarker of coagulopathy; however, the prognostic value of fibrinogen remains undefined in pediatric patients with sepsis. The aim of this study was to assess fibrinogen level on pediatric intensive care unit (PICU) admission and to elucidate the relationship…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:01

IL-33 Inhibits Hepatitis B Virus through Its Receptor ST2 in Hydrodynamic HBV Mouse Model
IL-33 Inhibits Hepatitis B Virus through Its Receptor ST2 in Hydrodynamic HBV Mouse Model: Interleukin-33 has been demonstrated to be associated with liver damage. However, its potential value in hepatitis B virus (HBV) infection remains unknown. This study was designed to investigate the role of IL-33 in hydrodynamic HBV mouse model. Different doses of IL-33 were used to treat HBV wild-type, ST2 knockout, CD8+ T depletion, NK depletion C57BL/6 mice and C.B-17 SCID and nod SCID mouse, respectively….

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:00

Propofol Attenuates Hypoxia-Induced Inflammation in BV2 Microglia by Inhibiting Oxidative Stress and NF-κB/Hif-1α Signaling
Propofol Attenuates Hypoxia-Induced Inflammation in BV2 Microglia by Inhibiting Oxidative Stress and NF-κB/Hif-1α Signaling: Hypoxia-induced neuroinflammation typically causes neurological damage and can occur during stroke, neonatal hypoxic-ischemic encephalopathy, and other diseases. Propofol is widely used as an intravenous anesthetic. Studies have shown that propofol has antineuroinflammatory effect. However, the underlying mechanism remains to be fully elucidated. Thus, we aimed to investigate…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

07:59

Resveratrol Attenuates High Glucose-Induced Vascular Endothelial Cell Injury by Activating the E2F3 Pathway
Resveratrol Attenuates High Glucose-Induced Vascular Endothelial Cell Injury by Activating the E2F3 Pathway: Type 2 diabetes mellitus (T2DM) is the most common metabolic disease. High glucose-induced macrovascular disease and microangiopathy are major complications of diabetes. E2F3, a member of the E2F transcription factor family, is closely related to cardiovascular diseases. Resveratrol, a nonflavonoid polyphenolic compound widely found in plants, has been shown to have cardiovascular protection….

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

07:59

Robotic Partial Nephrectomy with Indocyanine Green Fluorescence Navigation
Robotic Partial Nephrectomy with Indocyanine Green Fluorescence Navigation: Partial nephrectomy (PN) is a recommended type of treatment of localised renal tumors. Real-time intraoperative imaging technique, such as fluorescence imaging with indocyanine green (ICG) administration helps to improve intraoperative and postoperative outcomes in patients who underwent PN. Our work presents results of patients who underwent robotic PN with ICG navigation. A total of 37 patients underwent robotic PN with…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

07:58

Exosomes as Mediators of Cell-to-Cell Communication in Thyroid Disease
Exosomes as Mediators of Cell-to-Cell Communication in Thyroid Disease: Exosomes are a type of extracellular vehicle, formed by budding cell membranes, containing proteins, DNA, and RNA. Concentrated cargoes from parent cells are enveloped in exosomes, which are cell specific and may have functions in the recipient cell, reflecting a novel physiological and pathological mechanism in disease development. As a transmitter, exosomes shuttle to different cells or tissues and mediate communications among…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

07:58

Adenocarcinoma with Neuroendocrine Differentiation of the Colon Accompanying Osteoclast-Like Giant Cells
Adenocarcinoma with Neuroendocrine Differentiation of the Colon Accompanying Osteoclast-Like Giant Cells: Introduction. Neuroendocrine differentiation in colorectal cancer is reportedly associated with poorer grade of tumor differentiation, nodal and distant metastasis, and other unfavorable features, contributing to a worse clinical outcome. Colorectal cancer with osteoclast-like giant cells (OGCs) is extremely rare. Case Presentation. An 86-year-old woman was diagnosed as double cancer of the transverse…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

07:58

Association of Brain-Gut Peptides with Inflammatory Cytokines in Moyamoya Disease
Association of Brain-Gut Peptides with Inflammatory Cytokines in Moyamoya Disease: Systemic inflammation has been shown to play a pivotal role in the pathogenesis of moyamoya disease (MMD). Brain-gut peptides exhibit regulatory effects in the secretion of proinflammatory cytokines. To investigate the association between brain-gut peptides and inflammation in the occurrence of MMD, 41 patients with MMD, as well as 74 age- and sex-matched healthy individuals were enrolled. The levels of four brain-gut…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

07:57

A Small-Sized Population of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Shows High Stemness Properties and Therapeutic Benefit
A Small-Sized Population of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Shows High Stemness Properties and Therapeutic Benefit: Mesenchymal stem cells (MSCs) represent a promising means to promote tissue regeneration. However, the heterogeneity of MSCs impedes their use for regenerative medicine. Further investigation of this phenotype is required to develop cell therapies with improved clinical efficacy. Here, a small-sized population of human umbilical cord blood-derived MSCs (UCB-MSCs)…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

07:57

Crosstalk of MicroRNAs and Oxidative Stress in the Pathogenesis of Cancer
Crosstalk of MicroRNAs and Oxidative Stress in the Pathogenesis of Cancer: Oxidative stress refers to an imbalance between reactive oxygen species (ROS) generation and body’s capability to detoxify the reactive mediators or to fix the relating damage. MicroRNAs are considered to be important mediators that play essential roles in the regulation of diverse aspects of carcinogenesis. Growing studies have demonstrated that the ROS can regulate microRNA biogenesis and expression mainly through modulating…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

07:56

Pulmonary Alveolar Microlithiasis: An Isolated Case in a Hispanic Male
Pulmonary Alveolar Microlithiasis: An Isolated Case in a Hispanic Male: Pulmonary alveolar microlithiasis (PAM) is an uncommon hereditary lung disease characterized by widespread deposition of calcium phosphate microliths within the alveolar spaces. It is considered an autosomal recessive disease with a mutation in a gene encoding a sodium phosphate cotransporter. The imaging findings in the early phase of disease can be mistaken for miliary tuberculosis or sarcoidosis. However, the classic radiologic…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

07:55

Associations between the Neutrophil-to-Lymphocyte Ratio and Diabetic Complications in Adults with Diabetes: A Cross-Sectional Study
Associations between the Neutrophil-to-Lymphocyte Ratio and Diabetic Complications in Adults with Diabetes: A Cross-Sectional Study: Objective. The neutrophil-to-lymphocyte ratio (NLR) is an inexpensive and easily measurable laboratory index indicating systemic inflammation, while the application of many other inflammatory markers has been limited in daily clinical practice. However, large population studies about investigating the associations of the NLR level with diabetic complications including…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

07:43

Αφαίρεση διαφημίσεων


,
OtolaryngologyDeveloping world perspectives in otolaryngology: infectious complications in otolaryngologyNo abstract availableOtolaryngologyWed Apr 22, 2020 03:00Head and neck surgical antibiotic prophylaxis in resource-constrained settingsPurpose of review Antimicrobial resistance represents a global threat and causes almost 700 000 deaths per year. The rapid dissemination of resistant bacteria is occurring globally, turning this into the primary threat to public health in the 21st century and…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

07:42

,
Remove ads Plastic and Reconstructive Surgery – Current IssueA Structured Facial Feminization Fresh Tissue Surgical Simulation Laboratory Improves Trainee Confidence and KnowledgeNo abstract availablePlastic and Reconstructive Surgery – Current IssueTue Apr 28, 2020 09:49Discussion: Docosahexaenoic Acid Improves Diabetic Wound Healing in a Rat Model by Restoring Impaired Plasticity of Macrophage Progenitor CellsNo abstract availablePlastic and Reconstructive Surgery – Current IssueTue Apr 28, 2020…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

07:42

,
Respiratory Care current issueThe Timed Inspiratory Effort Index as a Weaning Predictor: Analysis of Intra- and Interobserver ReproducibilityBACKGROUND:Prolonged ventilatory weaning may expose patients to unnecessary discomfort, increase the risk of complications, and raise the costs of hospital treatment. In this scenario, indexes that reliably predict successful liberation can be helpful.OBJECTIVE:To evaluate the intra- and interobserver reproducibility of the timed inspiratory effort index as…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

07:41

,
Cellular and Molecular BiologyA potential ex vivo infection model of human induced pluripotent stem cell-3D organoids beyond coronavirus disease 2019.Related ArticlesA potential ex vivo infection model of human induced pluripotent stem cell-3D organoids beyond coronavirus disease 2019. Histol Histopathol. 2020 Apr 27;:18223 Authors: Zhou H, Liu LP, Fang M, Li YM, Zheng YW Abstract The novel coronavirus disease 2019 (COVID-19) outbreak began in the city of Wuhan, whereupon it rapidly spread throughout…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

07:40

,
Rare CancersAcute promyelocytic leukemia during pregnancy: A case report and 10-year institutional review of hematologic malignancies during pregnancy.Related ArticlesAcute promyelocytic leukemia during pregnancy: A case report and 10-year institutional review of hematologic malignancies during pregnancy. Pathol Res Pract. 2019 Dec;215(12):152672 Authors: Fei F, Faye-Petersen OM, Vachhani P, Jamy O, Reddy VV Abstract Acute promyelocytic leukemia (APL) manifesting during pregnancy is a very rare…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

07:39

,
Head and NeckThe functional head impulse test: Comparing gain and percentage of correct answers.Related ArticlesThe functional head impulse test: Comparing gain and percentage of correct answers. Prog Brain Res. 2019;248:241-248 Authors: Versino M, Colnaghi S, Corallo G, Mandalà M, Ramat S Abstract OBJECTIVES: The video head impulse test (vHIT) provides as output a gain value that summarizes the behavior of the vestibulo-ocular reflex as the ratio of a measure of eye movement to the corresponding…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

07:39

,
Head and NeckMajor head and neck reconstruction during the COVID-19 pandemic: The University of Pittsburgh approach.Related ArticlesMajor head and neck reconstruction during the COVID-19 pandemic: The University of Pittsburgh approach. Head Neck. 2020 Apr 27;: Authors: Ranasinghe V, Mady LJ, Kim S, Ferris RL, Duvvuri U, Johnson JT, Solari MG, Sridharan S, Kubik M Abstract The 2019 novel coronavirus (COVID-19) pandemic has created significant challenges to the delivery of care for patients with advanced…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

07:38

,
Alcohol and HomeostasisThe Timing of Water and Beverage Consumption During the Day Among Children and Adults in the United States: Analyses of NHANES 2011-2016 Data.Related ArticlesThe Timing of Water and Beverage Consumption During the Day Among Children and Adults in the United States: Analyses of NHANES 2011-2016 Data. Nutrients. 2019 Nov 08;11(11): Authors: Vieux F, Maillot M, Rehm CD, Barrios P, Drewnowski A Abstract Dietary Guidelines for Americans 2015-20 recommend replacing sugar sweetened…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

07:37

,
Latest Results for Applied Microbiology and BiotechnologyAnalysis of microbial contamination of household water purifiersAbstract Household water purifiers are increasingly used to treat drinking water at the household level, but their influence on the microbiological safety of drinking water has rarely been assessed. In this study, representative purifiers, based on different filtering processes, were analyzed for their impact on effluent water quality. The results showed that purifiers reduced…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

07:37

,
J Clin NeurosciApplication of the Willis Covered Stent in the treatment of intracranial unruptured aneurysms in internal carotid artery: A retrospective single-center experience.Related ArticlesApplication of the Willis Covered Stent in the treatment of intracranial unruptured aneurysms in internal carotid artery: A retrospective single-center experience. J Clin Neurosci. 2020 Apr 23;: Authors: Yan P, Zhang Y, Ma C, Liang F, Zhu H, Jiang C Abstract The purpose of this study was to retrospectively…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

07:36

,
Nature Communications – current – nature.com science feedsCytosine base editors with minimized unguided DNA and RNA off-target events and high on-target activityNature Communications, Published online: 28 April 2020; doi:10.1038/s41467-020-15887-5Cytosine base editors have been reported to induce off-target mutations in DNA and RNA. Here the authors identify next-generation CBEs with reduced guide-independent off-target editing profiles and retain high on-target editing activity.Nature Communications…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

07:36

,
pubmed: "world neurosurg"[jo…Management of Aneurysmal Subarachnoid Hemorrhage – Variation in Clinical Practice and Unmet Need for Follow-up among Survivors – A Single Center Perspective.Related ArticlesManagement of Aneurysmal Subarachnoid Hemorrhage – Variation in Clinical Practice and Unmet Need for Follow-up among Survivors – A Single Center Perspective. World Neurosurg. 2020 Apr 24;: Authors: Delpirou-Nouh C, Samkutty DG, Chandrashekhar S, Santucci JA, Ford L, Xu C, Hollabaugh KM, Bohnstedt…

Medicine by Alexandros G. Sfakianakis,

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

,
Rhinology Future Debates 2018, a EUFOREA Report.Related ArticlesRhinology Future Debates 2018, a EUFOREA Report. Rhinology. 2020 Apr 25;: Authors: Prokopakis E, Vardouniotis A, Bachert C, Bousquet J, Carrie S, Castelnuevo P, Constantinidis J, Fokkens W, Hopkins C, Leunig A, Molteni G, Mullol J, Scadding G, Marien G, Doulaptsi M, Hellings P Abstract The third Rhinology Future Debates was organized by the European Forum for Research and Education in Allergy and Airways diseases (EUFOREA) in 2018 in…Technologies…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:11

,
Navigation-assisted surgery for chondroblastoma arising in the femoral head: A case report.Related ArticlesNavigation-assisted surgery for chondroblastoma arising in the femoral head: A case report. Int J Surg Case Rep. 2020 Apr 19;70:8-12 Authors: Maru T, Imanishi J, Torigoe T, Saita K, Kadono Y, Yazawa Y Abstract INTRODUCTION: Surgery for chondroblastoma in the femoral head is challenging due to its inaccessibility, with high risk of local recurrence and poor functional outcomes reported. We herein…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:10

,
Palatopharyngoplasty and Palatal Anatomy and Phenotypes for Treatment of Sleep Apnea in the Twenty-first Century.Related ArticlesPalatopharyngoplasty and Palatal Anatomy and Phenotypes for Treatment of Sleep Apnea in the Twenty-first Century. Otolaryngol Clin North Am. 2020 Apr 22;: Authors: Puccia R, Woodson BT Abstract Successful palatopharyngoplasty is critical for successful sleep apnea surgery. Traditional uvulopalatopharyngoplasty was primarily excisional, whereas newer techniques, such as…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:09

,
Emergence of a multidrug-resistant ST 27 <i>Escherichia coli</i> co-harboring <i>bla</i>_NDM-1, <i>mcr-1,</i> and <i>fosA3</i> from a patient in ChinaThe Journal of Antibiotics – Issue – nature.com science feedsMon Apr 27, 2020 03:00Intraoperative use of optical coherence tomography to differentiate normal and diseased thyroid and parathyroid tissues from lymph node and fatAbstract The purpose of this study is twofold: (1) to determine…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:09

,
An evaluation of hepatocellular carcinoma practice guidelines from a radiation oncology perspective.Related ArticlesAn evaluation of hepatocellular carcinoma practice guidelines from a radiation oncology perspective. Radiother Oncol. 2020 Apr 02;148:73-81 Authors: Rim CH, Cheng J, Huang WY, Kimura T, Lee V, Zeng ZC, Seong J Abstract INTRODUCTION: External beam radiotherapy (EBRT) is actively used for hepatocellular carcinoma (HCC) treatment in clinical practice but has not got attention in several…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:08

,
Exceptional Response to Everolimus in a Patient with Metastatic Castrate-Resistant Prostate Cancer Harboring a PTEN Inactivating MutationProstate cancer is among the most common types of cancer in men. Early detection and proper medical intervention is crucial to ensuring successful treatment. Here we describe a patient clinically presenting with castrate-resistant prostate carcinoma. Comprehensive genomic profiling identified a PTEN inactivating mutation in the patient’s tumor. After being heavily…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:07

,
Which risk factors are associated with stomal recurrence after total laryngectomy for laryngeal cancer? A meta-analysis of the last 30 years.Related ArticlesWhich risk factors are associated with stomal recurrence after total laryngectomy for laryngeal cancer? A meta-analysis of the last 30 years. Braz J Otorhinolaryngol. 2020 Apr 11;: Authors: Liang J, Zhu X, Zeng W, Yu T, Fang F, Zhao Y Abstract INTRODUCTION: Stomal recurrence is a troublesome complication after total laryngectomy Despite a large…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:07

,
pubmed: "j cell physiol"[jou…SIRT3 deficiency is resistant to autophagy-dependent ferroptosis by inhibiting the AMPK/mTOR pathway and promoting GPX4 levels.Related ArticlesSIRT3 deficiency is resistant to autophagy-dependent ferroptosis by inhibiting the AMPK/mTOR pathway and promoting GPX4 levels. J Cell Physiol. 2020 Apr 24;: Authors: Han D, Jiang L, Gu X, Huang S, Pang J, Wu Y, Yin J, Wang J Abstract Ferroptosis, an autophagy-dependent cell death, is characterized by lipid peroxidation and…

Medicine by Alexandros G. Sfakianakis

,
Water, Vol. 12, Pages 1240: The Wicked Problem the Water Framework Directive Cannot Solve. The Governance Approach in Dealing with Pollution of Nutrients in Surface Water in the Netherlands, Flanders, Lower Saxony, Denmark and IrelandWater, Vol. 12, Pages 1240: The Wicked Problem the Water Framework Directive Cannot Solve. The Governance Approach in Dealing with Pollution of Nutrients in Surface Water in the Netherlands, Flanders, Lower Saxony, Denmark and Ireland Water doi: 10.3390/w12051240 Authors:…

Medicine by Alexandros G. Sfakianakis

09:16

,
Pharmaceutics, Vol. 12, Pages 389: Senescence of IPF Lung Fibroblasts Disrupt Alveolar Epithelial Cell Proliferation and Promote Migration in Wound HealingPharmaceutics, Vol. 12, Pages 389: Senescence of IPF Lung Fibroblasts Disrupt Alveolar Epithelial Cell Proliferation and Promote Migration in Wound Healing Pharmaceutics doi: 10.3390/pharmaceutics12040389 Authors: Kaj E. C. Blokland David W. Waters Michael Schuliga Jane Read Simon D. Pouwels Christopher L. Grainge Jade Jaffar Glen Westall Steven…

Medicine by Alexandros G. Sfakianakis

09:15

,
Nutrients, Vol. 12, Pages 1204: The Impact of Aerobic Exercise and Badminton on HDL Cholesterol Levels in Taiwanese AdultsNutrients, Vol. 12, Pages 1204: The Impact of Aerobic Exercise and Badminton on HDL Cholesterol Levels in Taiwanese Adults Nutrients doi: 10.3390/nu12051204 Authors: Yasser Nassef Kuan-Jung Lee Oswald Ndi Nfor Disline Manli Tantoh Ming-Chih Chou Yung-Po Liaw Elevated levels of high-density lipoprotein cholesterol (HDL-C) have been associated with a decreased risk of coronary heart…

Medicine by Alexandros G. Sfakianakis

09:14

,
Nanomaterials, Vol. 10, Pages 827: Incorporating Aminated Nanodiamonds to Improve the Mechanical Properties of 3D-Printed Resin-Based Biomedical AppliancesNanomaterials, Vol. 10, Pages 827: Incorporating Aminated Nanodiamonds to Improve the Mechanical Properties of 3D-Printed Resin-Based Biomedical Appliances Nanomaterials doi: 10.3390/nano10050827 Authors: Mangal Seo Yu Kwon Choi The creation of clinically patient-specific 3D-printed biomedical appliances that can withstand the physical stresses…

Medicine by Alexandros G. Sfakianakis

09:14

,
Microorganisms, Vol. 8, Pages 617: Composition and Predominance of Fusarium Species Causing Fusarium Head Blight in Winter Wheat Grain Depending on Cultivar Susceptibility and Meteorological FactorsMicroorganisms, Vol. 8, Pages 617: Composition and Predominance of Fusarium Species Causing Fusarium Head Blight in Winter Wheat Grain Depending on Cultivar Susceptibility and Meteorological Factors Microorganisms doi: 10.3390/microorganisms8040617 Authors: Tim Birr Mario Hasler Joseph-Alexander Verreet…

Medicine by Alexandros G. Sfakianakis

09:13

,
Journal of Clinical MedicineJCM, Vol. 9, Pages 1234: Incident Comorbidities, Aging and the Risk of Stroke in 608,108 Patients with Atrial Fibrillation: A Nationwide AnalysisJCM, Vol. 9, Pages 1234: Incident Comorbidities, Aging and the Risk of Stroke in 608,108 Patients with Atrial Fibrillation: A Nationwide Analysis Journal of Clinical Medicine doi: 10.3390/jcm9041234 Authors: Fauchier Bodin Bisson Herbert Spiesser Clementy Babuty Chao Lip Background: We hypothesized that the change in stroke risk…

Medicine by Alexandros G. Sfakianakis

09:13

,
International Journal of Molecular SciencesIJMS, Vol. 21, Pages 3009: Human NANOS1 Represses Apoptosis by Downregulating Pro-Apoptotic Genes in the Male Germ Cell LineIJMS, Vol. 21, Pages 3009: Human NANOS1 Represses Apoptosis by Downregulating Pro-Apoptotic Genes in the Male Germ Cell Line International Journal of Molecular Sciences doi: 10.3390/ijms21083009 Authors: Damian M. Janecki Erkut Ilaslan Maciej J. Smialek Marcin P. Sajek Maciej Kotecki Barbara Ginter-Matuszewska Patryk Krainski Jadwiga…

Medicine by Alexandros G. Sfakianakis

09:12

,
International Journal of Molecular SciencesIJMS, Vol. 21, Pages 3047: The Serine Protease Autotransporters TagB, TagC, and Sha from Extraintestinal Pathogenic Escherichia coli Are Internalized by Human Bladder Epithelial Cells and Cause Actin Cytoskeletal DisruptionIJMS, Vol. 21, Pages 3047: The Serine Protease Autotransporters TagB, TagC, and Sha from Extraintestinal Pathogenic Escherichia coli Are Internalized by Human Bladder Epithelial Cells and Cause Actin Cytoskeletal Disruption International…

Medicine by Alexandros G. Sfakianakis

09:11

,
International Journal of Environmental Research and Public HealthIJERPH, Vol. 17, Pages 2946: Residential Radon Exposure and Cigarette Smoking in Association with Lung Cancer: A Matched Case-Control Study in KoreaIJERPH, Vol. 17, Pages 2946: Residential Radon Exposure and Cigarette Smoking in Association with Lung Cancer: A Matched Case-Control Study in Korea International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082946 Authors: Eung Joo Park Hokyou Lee Hyeon Chang…

Medicine by Alexandros G. Sfakianakis

09:11

,
International Journal of Environmental Research and Public HealthIJERPH, Vol. 17, Pages 2994: Correlation between Caries, Body Mass Index and Occlusion in an Italian Pediatric Patients Sample: A Transverse Observational StudyIJERPH, Vol. 17, Pages 2994: Correlation between Caries, Body Mass Index and Occlusion in an Italian Pediatric Patients Sample: A Transverse Observational Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17092994 Authors: Militi Nucera…

Medicine by Alexandros G. Sfakianakis

09:10

,
Foods, Vol. 9, Pages 540: Comparison of Chemical Composition and Safety Issues in Fish Roe Products: Application of Chemometrics to Chemical DataFoods, Vol. 9, Pages 540: Comparison of Chemical Composition and Safety Issues in Fish Roe Products: Application of Chemometrics to Chemical Data Foods doi: 10.3390/foods9050540 Authors: Mauro Vasconi Erica Tirloni Simone Stella Chiara Coppola Annalaura Lopez Federica Bellagamba Cristian Bernardi Vittorio Maria Moretti Processed fish roes are acquiring considerable…

Medicine by Alexandros G. Sfakianakis

09:10

,
Cancers, Vol. 12, Pages 1053: Self-Collection for Cervical Screening Programs: From Research to RealityCancers, Vol. 12, Pages 1053: Self-Collection for Cervical Screening Programs: From Research to Reality Cancers doi: 10.3390/cancers12041053 Authors: David Hawkes Marco H. T. Keung Yanping Huang Tracey L. McDermott Joanne Romano Marion Saville Julia M. L. Brotherton In 2018, there were an estimated 570,000 new cases of cervical cancer globally, with most of them occurring in women who either had…

Medicine by Alexandros G. Sfakianakis

09:09

,
BiomoleculesBiomolecules, Vol. 10, Pages 664: Development and Characterization of a Novel Peptide-Loaded Antimicrobial Ocular InsertBiomolecules, Vol. 10, Pages 664: Development and Characterization of a Novel Peptide-Loaded Antimicrobial Ocular Insert Biomolecules doi: 10.3390/biom10050664 Authors: Eleonora Terreni Susi Burgalassi Patrizia Chetoni Silvia Tampucci Erica Zucchetti Roberta Fais Emilia Ghelardi Antonella Lupetti Daniela Monti Infectious ocular keratitis is the leading cause of blindness…

Medicine by Alexandros G. Sfakianakis

09:09

,
AntibioticsAntibiotics, Vol. 9, Pages 210: Cinnamon (Cinnamomum zeylanicum) Oil as a Potential Alternative to Antibiotics in PoultryAntibiotics, Vol. 9, Pages 210: Cinnamon (Cinnamomum zeylanicum) Oil as a Potential Alternative to Antibiotics in Poultry Antibiotics doi: 10.3390/antibiotics9050210 Authors: Mohamed E. Abd El-Hack Mahmoud Alagawany Abdel-Moneim E. Abdel-Moneim Noureldeen G. Mohammed Asmaa F. Khafaga May Bin-Jumah Sarah I. Othman Ahmed A. Allam Shaaban S. Elnesr The removal of antibiotic…

Medicine by Alexandros G. Sfakianakis

09:08

M
The Lancet[Correspondence] Rebuilding the broken health contract in ChileMany Chileans think that their country has lost its way. Massive protests highlight the need for a political reform to prioritise universal health care. The uncritical worship of the most extreme version of the free market by the Pinochet dictatorship led to the dismantling of the social contract and privatisation of the social security system. A system of personal retirement accounts was mandatory for new workers whereas the…

Medicine by Alexandros G. Sfakianakis

09:07

M
Thyroid Research and Practice : 2014 – 11(1)Redefining euthyroidism: A biopsychosocial constructSanjay Kalra, AG Unnikrishnan, Atul KalhanThyroid Research and Practice 2020 17(1):2-3Thyroid Research and Practice : 2014 – 11(1)2dITSCON 2019 AbstractsThyroid Research and Practice 2020 17(1):27-42Thyroid Research and Practice : 2014 – 11(1)2dCoronavirus disease 2019 and thyroid disease: Position statement of Indian Thyroid SocietyRajesh Rajput, Amit Agarwal, Mohd Ashraf Ganie, CS Bal, DC Sharma, Krishna…

Medicine by Alexandros G. Sfakianakis

09:07

M
Journal of Biological Chemistry current issueDetailed analyses of the crucial functions of Zn transporter proteins in alkaline phosphatase activation [Enzymology]Numerous zinc ectoenzymes are metalated by zinc and activated in the compartments of the early secretory pathway before reaching their destination. Zn transporter (ZNT) proteins located in these compartments are essential for ectoenzyme activation. We have previously reported that ZNT proteins, specifically ZNT5–ZNT6 heterodimers and ZNT7…

Medicine by Alexandros G. Sfakianakis

09:06

M
JAMA Online FirstCharacteristics of Hospitalized Adults With COVID-19 in an Integrated Health Care System in CaliforniaThis case series characterizes the demographics, health services use, and vital status and discharge dispositions of patients with polymerase chain reaction–confirmed coronavirus disease 2019 (COVID-19) hospitalized in the Kaiser Permanente Northern California health system in March 2020.JAMA Online First2dDiagnosis and Treatment of Opioid Use Disorder in 2020This JAMA Insights…

Medicine by Alexandros G. Sfakianakis

09:05

M
Latest Results for AngiogenesisApatinib as targeted therapy for advanced bone and soft tissue sarcoma: a dilemma of reversing multidrug resistance while suffering drug resistance itselfAbstract Bone and soft tissue sarcomas are rare malignant tumors originated from mesenchymal tissues. They harbor more than 50 distinct subtypes and differ in pathological features and clinical courses. Despite the significant improvements in modern multi-modality treatment, the outcomes and overall survival rates…

Medicine by Alexandros G. Sfakianakis

09:04

M
Latest ResultsSoluble receptor for advanced glycation end-products promotes angiogenesis through activation of STAT3 in myocardial ischemia/reperfusion injuryAbstract Soluble receptor for advanced glycation end-products (sRAGE), which exerts cardioprotective effect through inhibiting cardiomyocyte apoptosis and autophagy during ischemia/reperfusion (I/R) injury, is also known to enhance angiogenesis in post-ischemic reperfusion injury-critical limb ischemia (PIRI-CLI) mice. However, whether sRAGE…

Medicine by Alexandros G. Sfakianakis

09:04

M
Latest Results for Sleep and BreathingAssociation between sleep duration and asthma in different weight statuses (CHNS 2009–2015)Abstract Purpose Inadequate sleep duration affects asthma and weight. The associations among sleep duration, asthma, and different weight statuses in the Chinese population need to be further determined. Methods The study included 32,776 Chinese adults from the China Health and Nutrition Survey during 2009–2015. Self-reported sleep duration was classified…Latest Results…

Medicine by Alexandros G. Sfakianakis

09:03

M
BiomechanicsSex-Based Differences in Landing Mechanics Vary between the Drop Vertical Jump and Stop JumpPublication date: Available online 24 April 2020Source: Journal of BiomechanicsAuthor(s): Alexander T. Peebles, Laura C. Dickerson, Kristen E. Renner, Robin M. QueenBiomechanics2dErrata to “Modelling muscle recovery from a fatigued state in isometric contractions for the ankle joint”Publication date: Available online 23 April 2020Source: Journal of BiomechanicsAuthor(s): Ritwik Rakshit, James…

Medicine by Alexandros G. Sfakianakis

09:02

M
MCP Papers in PressA cross-linking mass spectrometry approach defines protein interactions in yeast mitochondria [Research]Protein cross-linking and the analysis of cross-linked peptides by mass spectrometry is currently receiving much attention. Not only is this approach applied to isolated complexes to provide information about spatial arrangements of proteins but it is also increasingly applied to entire cells and their organelles. As in quantitative proteomics, the application of isotopic labelling…

Medicine by Alexandros G. Sfakianakis

09:02

M
Physics in Medicine and Biology – latest papersPre-clinical evaluation of dual-layer spectral computed tomography-based stopping power prediction for particle therapy planning at the Heidelberg Ion Beam Therapy CenterAccurate beam range prediction during clinical treatment planning is key to improve targeted dose delivery in proton and heavy ion therapy. A substantial source of beam range uncertainty is the prediction of ion stopping power ratio (SPR) relative to water from an empirical calibration…

Medicine by Alexandros G. Sfakianakis

09:01

M
Cancer MedicineIDH1 and IDH2 mutations in lung adenocarcinomas: Evidences of subclonal evolutionIDH1/2 mutations in NSCLCs are uncommon. They occur in adenocarcinomas with high‐grade features and may be branching drivers leading to subclonal evolution. Abstract Background Selective IDH1 and IDH2 inhibitors have been approved for targeted therapy of acute myeloid leukemia. Clinical trials for solid tumors with IDH1 and IDH2 (IDH1/2) mutations are ongoing. Reports of IDH1/2‐mutated non–small cell…

Medicine by Alexandros G. Sfakianakis

09:00

M
pubmed: sleepEffects of the Characteristics and Duration of Chronic Pain on Psychosomatic Function in the Community-Dwelling Elderly Population.Effects of the Characteristics and Duration of Chronic Pain on Psychosomatic Function in the Community-Dwelling Elderly Population. Pain Res Manag. 2020;2020:4714527 Authors: Hida M, Nakamura M, Imaoka M, Nakao H, Tasaki F, Omizu T, Takeda M, Ohnishi T, Wada C Abstract Catastrophic thinking is related to pain intensity and the degree of disability and influences…

Medicine by Alexandros G. Sfakianakis

08:59

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
pubmed: sleepSleep Quality and Mental Disorder Symptoms among Canadian Public Safety Personnel.Related ArticlesSleep Quality and Mental Disorder Symptoms among Canadian Public Safety Personnel. Int J Environ Res Public Health. 2020 Apr 15;17(8): Authors: Angehrn A, Teale Sapach MJN, Ricciardelli R, MacPhee RS, Anderson GS, Carleton RN Abstract Poor sleep quality is associated with numerous mental health concerns and poorer overall physical health. Sleep disturbances are commonly reported by public…

Medicine by Alexandros G. Sfakianakis

08:58

M
pubmed: sleepNeutrophil extracellular traps in COVID-19.Related ArticlesNeutrophil extracellular traps in COVID-19. JCI Insight. 2020 Apr 24;: Authors: Zuo Y, Yalavarthi S, Shi H, Gockman K, Zuo M, Madison JA, Blair CN, Weber A, Barnes BJ, Egeblad M, Woods RJ, Kanthi Y, Knight JS Abstract In severe cases of coronavirus disease 2019 (COVID-19), viral pneumonia progresses to respiratory failure. Neutrophil extracellular traps (NETs) are extracellular webs of chromatin, microbicidal proteins, and oxidant…

Medicine by Alexandros G. Sfakianakis

08:58

M
pubmed: sleepInvited Topic: Individualized Care Is Superior to Standardized Care for the Majority of Critically Ill Patients.Related ArticlesInvited Topic: Individualized Care Is Superior to Standardized Care for the Majority of Critically Ill Patients. Crit Care Med. 2020 Apr 23;: Authors: Cortés-Puch I, Applefeld WN, Wang J, Danner RL, Eichacker PQ, Natanson C PMID: 32332282 [PubMed – as supplied by publisher]pubmed: sleep19hTop 10 evidence-based countermeasures for night shift workers.Related…

Medicine by Alexandros G. Sfakianakis

08:57

M
pubmed: philosophy for medic…Impact of lymphoma survivorship clinic visit on patient-centered outcomes.Related ArticlesImpact of lymphoma survivorship clinic visit on patient-centered outcomes. J Cancer Surviv. 2019 06;13(3):344-352 Authors: Viscuse P, Yost KJ, Jenkins S, Lackore K, Habermann T, Thanarajasingam G, Thompson C Abstract PURPOSE: Cancer survivors may experience physical, social, and emotional effects of cancer and its treatments. National Comprehensive Cancer Network (NCCN) guidelines…

Medicine by Alexandros G. Sfakianakis

08:57

M
pubmed: philosophy for medic…[Sacral nerve magnetic stimulation combined with extracorporeal shockwave for the treatment of type-ⅢB chronic prostatitis].Related Articles[Sacral nerve magnetic stimulation combined with extracorporeal shockwave for the treatment of type-ⅢB chronic prostatitis]. Zhonghua Nan Ke Xue. 2019 Jul;25(7):626-631 Authors: Yang JM, Xia W, Lü TT, Xi JH, Lü JW Abstract Objective: To investigate the clinical therapeutic effects of sacral nerve magnetic stimulation (SNMS) combined…

Medicine by Alexandros G. Sfakianakis

08:56

M
pubmed: philosophy for medic…Rethinking patient involvement in healthcare priority setting.Related ArticlesRethinking patient involvement in healthcare priority setting. Bioethics. 2020 May;34(4):403-411 Authors: Sandman L, Hofmann B, Bognar G Abstract With healthcare systems under pressure from scarcity of resources and ever-increasing demand for services, difficult priority setting choices need to be made. At the same time, increased attention to patient involvement in a wide range of settings…

Medicine by Alexandros G. Sfakianakis

08:55

M
CancersCancers, Vol. 12, Pages 1061: The Clinical Impact of Low-Volume Lymph Nodal Metastases in Early-Stage Cervical Cancer: The Senticol 1 and Senticol 2 TrialsCancers, Vol. 12, Pages 1061: The Clinical Impact of Low-Volume Lymph Nodal Metastases in Early-Stage Cervical Cancer: The Senticol 1 and Senticol 2 Trials Cancers doi: 10.3390/cancers12051061 Authors: Benedetta Guani Vincent Balaya Laurent Magaud Fabrice Lecuru Patrice Mathevet Background: With the development of the sentinel node technique…

Medicine by Alexandros G. Sfakianakis

08:55

Incidence of Occult Lymph Node Metastasis in Primary Larynx Squamous Cell Carcinoma, by Subsite, T Classification and Neck Level: A Systematic Review
Cancers, Vol. 12, Pages 1059: Incidence of Occult Lymph Node Metastasis in Primary Larynx Squamous Cell Carcinoma, by Subsite, T Classification and Neck Level: A Systematic Review: Cancers, Vol. 12, Pages 1059: Incidence of Occult Lymph Node Metastasis in Primary Larynx Squamous Cell Carcinoma, by Subsite, T Classification and Neck Level: A Systematic ReviewCancers doi: 10.3390/cancers12041059Authors: Alvaro Sanabria Jatin P. Shah Jesus E. Medina Kerry D. Olsen K. Thomas Robbins …

Medicine by Alexandros G. Sfakianakis

08:54

M
Scientific American Blog PostsOur Response to COVID-19 Is Male-CentricWe don’t know how the coronavirus may affect women and men differently, which prevents us from delivering appropriate and personalized care — Read more on ScientificAmerican.comScientific American Blog Posts13hMore Time Out in Nature is an Unexpected Benefit of the COVID-19 Sheltering RulesExploring the natural world can be restorative to mental health — Read more on ScientificAmerican.comScientific American Blog Posts22hThe…

Medicine by Alexandros G. Sfakianakis

08:53

Endogenously-Activated Ultrasmall-in-Nano Therapeutics: Assessment on 3D Head and Neck Squamous Cell Carcinomas
Cancers, Vol. 12, Pages 1063: Endogenously-Activated Ultrasmall-in-Nano Therapeutics: Assessment on 3D Head and Neck Squamous Cell Carcinomas: Cancers, Vol. 12, Pages 1063: Endogenously-Activated Ultrasmall-in-Nano Therapeutics: Assessment on 3D Head and Neck Squamous Cell CarcinomasCancers doi: 10.3390/cancers12051063Authors: Melissa Santi Ana Katrina Mapanao Domenico Cassano Ylea Vlamidis Valentina Cappello Valerio Voliani Negative or positive HPV-associated Head and Neck Squamous…

Medicine by Alexandros G. Sfakianakis

08:53

Post-Treatment HPV Surface Brushings and Risk of Relapse in Oropharyngeal Carcinoma
Cancers, Vol. 12, Pages 1069: Post-Treatment HPV Surface Brushings and Risk of Relapse in Oropharyngeal Carcinoma: Cancers, Vol. 12, Pages 1069: Post-Treatment HPV Surface Brushings and Risk of Relapse in Oropharyngeal CarcinomaCancers doi: 10.3390/cancers12051069Authors: Kofler Borena Dudas Innerhofer Dejaco Steinbichler Widmann von Laer Riechelmann Human papillomavirus (HPV)-positive oropharyngeal squamous cell carcinoma (OPSCC) is a distinct subtype of head…

Medicine by Alexandros G. Sfakianakis

08:52

Imaging Accuracy in Preoperative Staging of T3-T4 Laryngeal Cancers
Cancers, Vol. 12, Pages 1074: Imaging Accuracy in Preoperative Staging of T3-T4 Laryngeal Cancers: Cancers, Vol. 12, Pages 1074: Imaging Accuracy in Preoperative Staging of T3-T4 Laryngeal CancersCancers doi: 10.3390/cancers12051074Authors: Marco Benazzo Fabio Sovardi Lorenzo Preda Simone Mauramati Sergio Carnevale Giulia Bertino Francesca Berton Matteo Meroni Irene Herman Giuseppe Trisolini Patrizia Morbini Background: Preoperative imaging impacts treatment planning…

Medicine by Alexandros G. Sfakianakis

08:51

M
Allergy and Clinical ImmunologyWill environmental impacts of social distancing due to the SARS-CoV-2 pandemic decrease allergic disease?Allergy and Clinical Immunology8hBarrier dysfunction in the atopic march—how does atopic dermatitis lead to asthma in children?Allergy and Clinical Immunology1dAssociations of alpha and gamma-tocopherol during early life with lung function in childhoodEarly life α-tocopherol levels associated with better lung function if γ-tocopherol levels were low, suggesting…

Medicine by Alexandros G. Sfakianakis

08:50

Αφαίρεση διαφημίσεων


M
Health and Quality of Life Outcomes – Latest ArticlesHealth-related quality of life measured using the EQ-5D–5 L: population norms for the capital of IranEQ-5D is the most commonly used generic preference-based health-related quality of life (HRQoL) measure. The current study aimed at estimating the HRQoL index scores using EQ-5D-5 L measure in the capital of I…Health and Quality of Life Outcomes – Latest Articles6hQuality of life impact of refractive correction (QIRC) results three years after…

Medicine by Alexandros G. Sfakianakis

08:49

M
Latest ResultsCorrelation between urinary chromium level and semen quality in men attending an andrology laboratoryAbstract Chromium is an essential element that is required for the normal physiology but can be toxic to humans above a certain level. In spite of growing interest in research on chromium exposure to human health consensus about its effect on human, semen quality has not been achieved. The aim of the present study is to evaluate the impact of chromium exposure on semen parameters. A…

Medicine by Alexandros G. Sfakianakis

08:48

Rational Use of Tocilizumab in the Treatment of Novel Coronavirus Pneumonia
Rational Use of Tocilizumab in the Treatment of Novel Coronavirus Pneumonia: AbstractSince December 2019, a novel coronavirus pneumonia (COVID-19) has broken out in Wuhan, China and spread rapidly. Recent studies have found that ⁓ 15.7% of patients develop severe pneumonia, and cytokine storm is an important factor leading to rapid disease progression. Currently, there are no specific drugs for COVID-19 and the cytokine storm it causes. IL-6 is one of the key cytokines involved in infection-induced…

Medicine by Alexandros G. Sfakianakis

08:47

Occupational exposure to pesticides and associated health effects among greenhouse farm workers
Occupational exposure to pesticides and associated health effects among greenhouse farm workers: AbstractThe number and production capacities of greenhouse farms have been increased across the globe, driven by an effort for addressing food security problems related to the rapid population growth and the effects of climate change. As a result, there was a large increase in the number of greenhouse farm workers who are typically involved in chemical preparations and pesticide sprayings, crop harvesting,…

Medicine by Alexandros G. Sfakianakis

08:44

M
BMJ Open Current IssueProtocol for a systematic review of health promotion interventions for African Americans delivered in US barbershops and hair salonsIntroductionAfrican American adults are disproportionately burdened by chronic diseases, particularly at younger ages. Developing culturally appropriate interventions is paramount to closing the gap in these health inequities. The purpose of this systematic review is to critically evaluate health promotion interventions for African Americans delivered…

Medicine by Alexandros G. Sfakianakis

08:37

Recurrent syncope while eating: an unusual presentation of a diaphragmatic hernia
Recurrent syncope while eating: an unusual presentation of a diaphragmatic hernia:

Medicine by Alexandros G. Sfakianakis

08:36

Submandibular lymphadenitis due to Mycobacterium malmoense: first reported case from Greece
Submandibular lymphadenitis due to Mycobacterium malmoense: first reported case from Greece: An 8-year-old girl with subacute submandibular lymphadenitis and no other complaints is described. After failure of parenteral antistaphylococcal therapy, she underwent incision and drainage of the involved lymph node. The responsible pathogen was identified as Mycobacterium malmoense by GenoType CM assay and sequencing of the 16S ribosomalRNA (rRNA) gene. The patient remains healthy, 11 months after surgery,…

Medicine by Alexandros G. Sfakianakis

08:36

M
Hindawi Publishing CorporationMultimode Process Monitoring Method Based on Multiblock Projection Nonnegative Matrix FactorizationA multimode process monitoring method based on multiblock projection nonnegative matrix factorization (MPNMF) is proposed for traditional process monitoring methods which often adopt global model of data and ignore local information of data. Firstly, the training data set of each mode is partitioned by the complete link algorithm and the multivariate data space is divided…

Medicine by Alexandros G. Sfakianakis

08:32

head and neck
AA pubmed: head and neckInverted papilloma with multifocal attachment is associated with increased recurrence.Related ArticlesInverted papilloma with multifocal attachment is associated with increased recurrence. Int Forum Allergy Rhinol. 2019 08;9(8):865-869 Authors: Tong CCL, Patel NN, Maina IW, Triantafillou V, Yan CH, Kuan EC, Kohanski MA, Papagiannopoulos P, Workman AD, Cohen NA, Kennedy DW, Adappa ND, Palmer JN Abstract BACKGROUND: Inverted papilloma (IP) is a benign sinonasal tumor with a…

Medicine by Alexandros G. Sfakianakis

08:31

head and neck
AA pubmed: head and neckThe Nasal Swell Body and Septal Perforation Repair.The Nasal Swell Body and Septal Perforation Repair. Laryngoscope. 2020 Apr 23;: Authors: Ghorab S, Taylor CM, Bansberg SF Abstract OBJECTIVES: To review our experience with secondary surgery for persistent nasal obstruction following successful septal perforation repair and describe the potential contribution of the nasal swell body (NSB) to obstruction. STUDY DESIGN: Retrospective chart review. METHODS: IRB-approved retrospective…AA…

Medicine by Alexandros G. Sfakianakis

08:29

Rocuronium provides better surgical conditions and allows for the use of lower doses of remifentanil as compared to succinylcholine and cisatracurium in ML. This makes it possible to decrease the time to awakening and the complications associated with high doses of remifentanil.
Study of Rocuronium-Sugammadex as an Alternative to Succinylcholine-Cisatracurium in Microlaryngeal Surgery.: Study of Rocuronium-Sugammadex as an Alternative to Succinylcholine-Cisatracurium in Microlaryngeal Surgery.Laryngoscope. 2020 Apr 23;:Authors: Aragón-Benedí C, Visiedo-Sánchez S, Pascual-Bellosta A, Ortega-Lucea S, Fernández-Liesa R, Martínez-Ubieto J, Research Group in Anesthesia, Resuscitation AND Perioperative Medicine of Aragón Health Research Institute (IIS Aragón)Abstract Microlaryngeal…

Medicine by Alexandros G. Sfakianakis

08:27

head and neck
AA pubmed: head and neckDiagnosis of laryngeal tuberculosis in a high TB burden area.Related ArticlesDiagnosis of laryngeal tuberculosis in a high TB burden area. Eur Arch Otorhinolaryngol. 2020 Apr 23;: Authors: Matimba A, Moncho M, Musoke J, Seedat RY Abstract PURPOSE: The larynx is the second most commonly affected site in the head and neck region in patients with extrapulmonary tuberculosis (TB). Despite this, the prevalence of laryngeal TB is largely unknown, particularly in areas with a high…

Medicine by Alexandros G. Sfakianakis

08:27

Study of Rocuronium-Sugammadex as an Alternative to Succinylcholine-Cisatracurium in Microlaryngeal Surgery.
Study of Rocuronium-Sugammadex as an Alternative to Succinylcholine-Cisatracurium in Microlaryngeal Surgery.: Study of Rocuronium-Sugammadex as an Alternative to Succinylcholine-Cisatracurium in Microlaryngeal Surgery.Laryngoscope. 2020 Apr 23;:Authors: Aragón-Benedí C, Visiedo-Sánchez S, Pascual-Bellosta A, Ortega-Lucea S, Fernández-Liesa R, Martínez-Ubieto J, Research Group in Anesthesia, Resuscitation AND Perioperative Medicine of Aragón Health Research Institute (IIS Aragón)Abstract Microlaryngeal…

Medicine by Alexandros G. Sfakianakis

08:26

head and neck
AA pubmed: head and neckAn Anatomical Site and Genetic-Based Prognostic Model for Patients With Nuclear Protein in Testis (NUT) Midline Carcinoma: Analysis of 124 Patients.Related ArticlesAn Anatomical Site and Genetic-Based Prognostic Model for Patients With Nuclear Protein in Testis (NUT) Midline Carcinoma: Analysis of 124 Patients. JNCI Cancer Spectr. 2020 Apr;4(2):pkz094 Authors: Chau NG, Ma C, Danga K, Al-Sayegh H, Nardi V, Barrette R, Lathan CS, DuBois SG, Haddad RI, Shapiro GI, Sallan SE,…

Medicine by Alexandros G. Sfakianakis

08:25

head and neck
AA pubmed: head and neckEffects on migraine, neck pain, and head and neck posture, of temporomandibular disorder treatment: Study of a retrospective cohort.Related ArticlesEffects on migraine, neck pain, and head and neck posture, of temporomandibular disorder treatment: Study of a retrospective cohort. Arch Oral Biol. 2020 Apr 18;114:104718 Authors: Kang JH Abstract OBJECTIVES: The present study purposed to observe the response of comorbidities of temporomandibular disorders (TMD) including migraine…

Medicine by Alexandros G. Sfakianakis

08:23

M
Latest Results for European Journal of PediatricsReliability and concurrent validity of a modified timed up and go test for healthy preschoolersAbstract The purpose of this study was to assess the interrater and test-retest reliability and the concurrent validity of the modified timed up and go test for preschoolers. As such, we aim to determine the most suited outcome of the modified timed up and go test: the best or the average performance. Thirty-two children (age 3–5) performed three timed up…

Medicine by Alexandros G. Sfakianakis

08:21

Tolerability of Palmitoylethanolamide in a Pediatric Population Suffering from Migraine: A Pilot Study
Tolerability of Palmitoylethanolamide in a Pediatric Population Suffering from Migraine: A Pilot Study: Background. Palmitoylethanolamide (PEA) is emerging as a new therapeutic approach in pain and inflammatory conditions, and it has been evaluated in studies on various painful diseases. The aim of this open-label study was to evaluate the efficacy of ultramicronized PEA (umPEA) in the prophylactic treatment of migraine. Methods. The study included 70 patients with mean age of 10.3 ± 2.7 (24.5% M…

Medicine by Alexandros G. Sfakianakis

08:21

Efficacy of Amflow®, a Real-Time-Portable Feedback Device for Delivering Appropriate Ventilation in Critically Ill Patients: A Randomised, Controlled, Cross-Over Simulation Study
Efficacy of Amflow®, a Real-Time-Portable Feedback Device for Delivering Appropriate Ventilation in Critically Ill Patients: A Randomised, Controlled, Cross-Over Simulation Study: Objective. The aim of this study was to test whether Amflow® (a newly designed portable ventilation feedback device) can assist rescuers in delivering target tidal volume () and respiration rate (RR) during self-inflating bag (SB) ventilations in various clinical scenarios. Method. This was a simulation study with a prospective…

Medicine by Alexandros G. Sfakianakis

08:20

Successful Liposteroid Therapy for a Recurrent Idiopathic Pulmonary Hemosiderosis with Down Syndrome
Successful Liposteroid Therapy for a Recurrent Idiopathic Pulmonary Hemosiderosis with Down Syndrome: Idiopathic pulmonary hemosiderosis (IPH) is a rare and life-threatening disorder. Early diagnosis and appropriate management are essential for their better prognosis and patients’ quality of life (QOL). It is considered that Down syndrome patients with IPH have a worse prognosis compared to other IPH cases. A 2-year-old girl with Down syndrome received the diagnosis of IPH after two episodes of massive…

Medicine by Alexandros G. Sfakianakis

08:19

M
Hindawi Publishing CorporationEfficacy of the Combined Administration of Systemic and Intra-Articular Tranexamic Acid in Total Hip Arthroplasty Secondary to Femoral Neck Fracture: A Retrospective StudyBackground. Total hip arthroplasty (THA) is associated with substantial blood loss in the postoperative course. Tranexamic acid (TXA) is a potent antifibrinolytic agent, routinely administered by intravenous (IV) and topical (intra-articular, IA) route, which can possibly interrupt the cascade of events…

Medicine by Alexandros G. Sfakianakis

08:11

Αφαίρεση διαφημίσεων


The GRACE Scale in the Prognosis of Patients with Takotsubo Syndrome
The GRACE Scale in the Prognosis of Patients with Takotsubo Syndrome: Background. The prognosis of Takotsubo syndrome (TTS) is comparable to that of the non-ST-elevation myocardial infarction (NSTEMI). The GRACE scale is used to assess the risk of premature and long-term mortality in patients with NSTEMI in order to select the most favorable treatment strategy. Methods. 101 patients with TTS hospitalized in four centers of invasive cardiology in Podlaskie Voivodeship during the period 2008–2012 were…

Medicine by Alexandros G. Sfakianakis

08:11

Efficacy and Safety of Non-Vitamin K Anticoagulants for Atrial Fibrillation in Relation to Different Renal Function Levels: A Network Meta-Analysis
Efficacy and Safety of Non-Vitamin K Anticoagulants for Atrial Fibrillation in Relation to Different Renal Function Levels: A Network Meta-Analysis: Background. We performed a network meta-analysis (NMA) comparing the efficacy (stroke or systemic embolism) and safety (major bleeding) among different non-vitamin K antagonist oral anticoagulants (NOACs) in patients with atrial fibrillation (AF) and renal impairment, with the aim of recommending the proper drug and the dose based on renal function….

Medicine by Alexandros G. Sfakianakis

08:10

A Rare Cause of Hypophosphatemia: Raine Syndrome Changing Clinical Features with Age
A Rare Cause of Hypophosphatemia: Raine Syndrome Changing Clinical Features with Age: AbstractRaine Syndrome (RS) is caused by biallelic loss-of-function mutations in FAM20C gene and characterized by hypophosphatemia, typical facial and skeletal features. Subperiosteal bone formation and generalized osteosclerosis are the most common radiological findings. Here we present a new case with RS. A 9-month-old male patient on a home-type ventilator was referred for hypophosphatemia. He was born with a…

Medicine by Alexandros G. Sfakianakis

08:04

M
Hindawi Publishing CorporationModeling, Synchronization, and FPGA Implementation of Hamiltonian Conservative HyperchaosConservative chaotic systems have potentials in engineering application because of their superiority over the dissipative systems in terms of ergodicity and integer dimension. In this paper, five-dimension Euler equations are constructed by integrating two of sub-Euler equations, which are contributory to the exploration of higher-dimensional systems. These Euler equations compose…

Medicine by Alexandros G. Sfakianakis

08:03

Clinical Significance of Hepatocyte Growth Factor and Transforming Growth Factor-Beta-1 Levels in Assessing Disease Activity in Inflammatory Bowel Disease
Clinical Significance of Hepatocyte Growth Factor and Transforming Growth Factor-Beta-1 Levels in Assessing Disease Activity in Inflammatory Bowel Disease: Background. Transforming growth factor-beta (TGF-β) and hepatocyte growth factor (HGF) are inflammatory cytokines which function as key regulators of immunological homeostasis and inflammatory responses. They have been linked to inflammatory bowel diseases (IBD). In this study, we aim to assess the levels of TGF-β and HGF and other inflammatory…

Medicine by Alexandros G. Sfakianakis

08:02

Early Response to Definitive Chemoradiation for Esophageal Carcinoma Cuniculatum
A Case Report of an Early Response to Definitive Chemoradiation for Esophageal Carcinoma Cuniculatum: This case report describes a 63-year-old female with a locally advanced esophageal carcinoma cuniculatum treated with definitive chemoradiation who had a rapid and early response. This case is illustrative of an aggressive behavior with rapid response and rapid recurrence. The cases of esophageal carcinoma cuniculatum as well as the closely related clinical entity of verrucous carcinoma are reviewed…

Medicine by Alexandros G. Sfakianakis

08:02

Listeria Cerebritis with Tumor Necrosis Factor Inhibition
Listeria Cerebritis with Tumor Necrosis Factor Inhibition: Background. Listeria monocytogenes is historically a central nervous system pathogen of consideration in the very young, very old, and immune suppressed. Diagnosis of Listeria is based on positive bodily fluid culture or PCR testing. Cerebral edema is nonspecific and can be a manifestation of vasculitis, trauma, anoxia, ischemia, infarction, malignancy, or an infectious process. A main mechanism of immune protection against Listeria is tumor…

Medicine by Alexandros G. Sfakianakis

08:01

Neuromyelitis Optica Spectrum Disorder Attack Triggered by Herpes Zoster Infection
Neuromyelitis Optica Spectrum Disorder Attack Triggered by Herpes Zoster Infection: Neuromyelitis optica spectrum disorder is a severe autoimmune disease of the central nervous system characterized by recurrent inflammatory events primarily involving the optic nerves and spinal cord. Recently, a triggering role of infectious events in the development of NMOSD has been suggested. Varicella zoster virus is the most common viral infection involved, though the linkage with anti-aquaporin-4 antibodies…

Medicine by Alexandros G. Sfakianakis

08:01

Symptomatic Internal Carotid Agenesis in Children
Symptomatic Internal Carotid Agenesis in Children: Carotid artery agenesis is a rare congenital anomaly, and there are controversies in the leading cause for it. We present a 6-year-old girl with resolved focal neurological ischemic stroke that showed bilateral internal carotid artery (ICA) agenesis. Through this paper, we highlight the carotid canal congenital obliteration hypothesis as it may be a risk for such finding.

Medicine by Alexandros G. Sfakianakis

08:00

M
Canadian Medical Association Journal current issueHookah smoking and COVID-19: call for action [Letters]Canadian Medical Association Journal current issue32mSafety considerations with chloroquine, hydroxychloroquine and azithromycin in the management of SARS-CoV-2 infection [Review]Canadian Medical Association Journal current issue32mCalibration and discrimination of the Framingham Risk Score and the Pooled Cohort Equations [Research]BACKGROUND:Although accurate risk prediction is essential in guiding…

Medicine by Alexandros G. Sfakianakis

07:59

#
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia,

Telephone consultation 11855 int 1193,

Medicine by Alexandros G. Sfakianakis

COVID-19 and RAS: Unravelling an Unclear Relationship
IJMS, Vol. 21, Pages 3003: COVID-19 and RAS: Unravelling an Unclear Relationship: IJMS, Vol. 21, Pages 3003: COVID-19 and RAS: Unravelling an Unclear RelationshipInternational Journal of Molecular Sciences doi: 10.3390/ijms21083003Authors: Damiano D’Ardes Andrea Boccatonda Ilaria Rossi Maria Teresa Guagnano Francesca Santilli Francesco Cipollone Marco Bucci The renin-angiotensin system (RAS) plays a main role in regulating blood pressure and electrolyte and liquid balance. Previous…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

11:08

M
ResourcesResources, Vol. 9, Pages 49: Grazing Management, Forage Production and Soil Carbon DynamicsResources, Vol. 9, Pages 49: Grazing Management, Forage Production and Soil Carbon Dynamics Resources doi: 10.3390/resources9040049 Authors: Mark E. Ritchie Soil carbon pools remain a target for sequestering greenhouse gases, but appropriate land management options to achieve such sequestration remain uncertain. Livestock grazing can have profound positive or negative effects on soil carbon. Different…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

11:08

M
MoleculesMolecules, Vol. 25, Pages 1948: Design, Synthesis, and Biological Evaluation of Proteolysis Targeting Chimeras (PROTACs) for the Dual Degradation of IGF-1R and SrcMolecules, Vol. 25, Pages 1948: Design, Synthesis, and Biological Evaluation of Proteolysis Targeting Chimeras (PROTACs) for the Dual Degradation of IGF-1R and Src Molecules doi: 10.3390/molecules25081948 Authors: Sudhakar Manda Na Keum Lee Dong-Chan Oh Jeeyeon Lee A focused PROTAC library was developed to degrade both IGF-1R…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

11:07

M
MicroorganismsMicroorganisms, Vol. 8, Pages 609: Incidental Prophylactic Appendectomy Is Associated with a Profound Microbial Dysbiosis in the Long-TermMicroorganisms, Vol. 8, Pages 609: Incidental Prophylactic Appendectomy Is Associated with a Profound Microbial Dysbiosis in the Long-Term Microorganisms doi: 10.3390/microorganisms8040609 Authors: Lidia Sánchez-Alcoholado José Carlos Fernández-García Carolina Gutiérrez-Repiso M Rosa Bernal-López Luis Ocaña-Wilhelmi Eduardo García-Fuentes Isabel…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

11:07

M
International Journal of Molecular SciencesIJMS, Vol. 21, Pages 2961: Glycyrrhizin Inhibits PEDV Infection and Proinflammatory Cytokine Secretion via the HMGB1/TLR4-MAPK p38 PathwayIJMS, Vol. 21, Pages 2961: Glycyrrhizin Inhibits PEDV Infection and Proinflammatory Cytokine Secretion via the HMGB1/TLR4-MAPK p38 Pathway International Journal of Molecular Sciences doi: 10.3390/ijms21082961 Authors: Ruyi Gao Yongshuai Zhang Yuhui Kang Weiyin Xu Luyao Jiang Tingting Guo Changchao Huan Our previous study…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

11:07

M
International Journal of Environmental Research and Public HealthIJERPH, Vol. 17, Pages 2911: Perceptions on Connecting Respite Care Volunteers and CaregiversIJERPH, Vol. 17, Pages 2911: Perceptions on Connecting Respite Care Volunteers and Caregivers International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082911 Authors: Solange Campos-Romero Valeria Herskovic Carolina Fuentes Esmeralda Abarca The most common requirement for informal caregivers is to experience a…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

11:06

M
CellsCells, Vol. 9, Pages 1053: Lactate Increases Renal Cell Carcinoma Aggressiveness through Sirtuin 1-Dependent Epithelial Mesenchymal Transition Axis RegulationCells, Vol. 9, Pages 1053: Lactate Increases Renal Cell Carcinoma Aggressiveness through Sirtuin 1-Dependent Epithelial Mesenchymal Transition Axis Regulation Cells doi: 10.3390/cells9041053 Authors: Vera Miranda-Gonçalves Ana Lameirinhas Catarina Macedo-Silva João Lobo Paula C. Dias Verónica Ferreira Rui Henrique Carmen Jerónimo Background:…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

11:06

Adaptive evolution of hybrid bacteria by horizontal gene transfer [NEW RESULTS]
Adaptive evolution of hybrid bacteria by horizontal gene transfer [NEW RESULTS]: Horizontal gene transfer is an important factor in bacterial evolution that can act across species boundaries. Yet, we know little about rate and genomic targets of cross-lineage gene transfer, and about its effects on the recipient organism’s physiology and fitness. Here, we address these questions in a parallel evolution experiment with two Bacillus subtilis lineages of 7% sequence divergence. We observe rapid evolution…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

11:05

M
Rejuvenation ResearchHow Could We Slow or Reverse the Human Aging Process and Extend the Healthy Life Span with Heterochronous Autologous Hematopoietic Stem Cell TransplantationRejuvenation Research, Volume 23, Issue 2, Page 159-170, April 2020.Rejuvenation ResearchFri Apr 17, 2020 10:00Mark above section as read Latest Results for Folia MicrobiologicaCharacterization and optimization of abamectin—a powerful antiparasitic from a local Streptomyces avermitilis isolateAbstract Abamectin (ABA) constitutes…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

11:05

M
Angewandte Chemie International EditionBright Science Award for Marc Hillmyer / Hanwha‐Total IUPAC Young Scientist AwardsAngewandte Chemie International EditionTue Apr 21, 2020 16:28Synthesis of Galactosyl‐Queuosine and Distribution of Hypermodified Q‐Nucleosides in Mouse TissuesThe first total synthesis of the hypermodified RNA nucleoside galactosyl‐queuosine (galQ) was achieved. Moreover, the distribution of this nucleoside as well as mannosyl‐queuosine and queuosine was determined in tissues…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

11:04

M
Wiley: Dermatologic Therapy: Table of ContentsRefractory Classic Juvenile Pityriasis Rubra Pilaris Successfully Treated with a Combination of Etanercept and MethotrexateWiley: Dermatologic Therapy: Table of ContentsMon Apr 20, 2020 18:26Challenges of Covid‐19 Pandemic for DermatologyAbstract SARS‐CoV‐2 is a new corona virus responsible for the pandemic named Coronavirus Disease 2019 (COVID‐19). The disease causes severe acute respiratory syndromes with a significant morbidity and mortality. We provide…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

11:03

M
Wiley: EFSA Journal: Table of ContentsEvaluation of an alternative method for production of biodiesel from processed fats derived from Category 1, 2 and 3 animal by‐products (submitted by College Proteins)Abstract An alternative method for the production of biodiesel from processed fats derived from Category 1, 2 and 3 animal by‐products was assessed. The method is based on a pre‐cleaning process, acidic esterification/transesterification of tallow using 1.5% methanesulfonic acid w/w; 140°C; 5.5…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

11:03

M
Plastic and Reconstructive Surgery – Published Ahead-of-PrintTissue-Engineered Soft-Tissue Reconstruction Using Noninvasive Mechanical Preconditioning and a Shelf-Ready Allograft Adipose MatrixNo abstract availablePlastic and Reconstructive Surgery – Published Ahead-of-PrintMon Apr 20, 2020 03:00Recipient Site Preconditioning with Deferoxamine Increases Fat-Graft Survival by Inducing VEGF and Neovascularization in a Rat ModelNo abstract availablePlastic and Reconstructive Surgery – Published Ahead-of-PrintMon…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

11:02

M
Evolutionary Biology News — ScienceDailyDNA may not be life’s instruction book — just a jumbled list of ingredientsThe common view of heredity is that all information passed down from one generation to the next is stored in an organism’s DNA. But one research suggests this might not be so. In two new papers, he argues DNA is just the ingredient list, not the set of instructions used to build and maintain a living organism. The instructions, he says, are stored in the molecules that regulate a…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

11:02

M
Journal of CytologyFine-needle cytological characteristics of carcinoma breast with medullary or medullary-like features masquerading as dendritic reticulum cell sarcoma: An attempt to explore the reasons for erroneous cytologic interpretationDilip K Das, Shahed K Pathan, Zafar A Sheikh, Mrinmay K Mallik, Bency John, Fatma MothafferJournal of Cytology 2020 37(2):99-107 Background: Infiltration of tumors by dendritic reticulum cells (DRC) reflects the host immune defense mechanism. We observed three…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

11:01

M
bioRxiv Subject Collection: Evolutionary BiologySources of Intraspecific Morphological Variation in Vipera seoanei: Allometry, Sex, and Colour Phenotype [NEW RESULTS]Snakes frequently exhibit ontogenetic and sexual variation in head dimensions, as well as the occurrence of distinct colour morphotypes which might be fitness-related. In this study, we used linear biometry and geometric morphometrics to investigate intraspecific morphological variation related to allometry and sexual dimorphism in…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

11:01

Vascular
ScienceDirect Publication: European Journal of and Endovascular SurgeryCerebral Small Vessel Disease in Standard Pre-operative Imaging Reports Is Independently Associated with Increased Risk of Cardiovascular Death Following Carotid EndarterectomyPublication date: Available online 21 April 2020Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Nathalie Timmerman, Marjolijn L. Rots, Ian D. van Koeverden, Saskia Haitjema, Constance J.H.C.M. van Laarhoven, Annemiek M. Vuurens,…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

11:00

Therapeutics
Biomedicine & PharmacotherapyWhite tea and its active polyphenols lower cholesterol through reduction of very-low-density lipoprotein production and induction of LDLR expressionPublication date: July 2020Source: Biomedicine & Pharmacotherapy, Volume 127Author(s): Kun Luo, Chengmei Ma, Shaofang Xing, Yannan An, Juan Feng, Honglei Dang, Wenting Huang, Liansheng Qiao, Jing Cheng, Lan XieBiomedicine & PharmacotherapyThu Apr 23, 2020 14:23Research progress in use of traditional Chinese medicine…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:59

Dysphagia
DysphagiaSwallow Safety is Determined by Bolus Volume During Infant Feeding in an Animal ModelAbstract Feeding difficulties are especially prevalent in preterm infants, although the mechanisms driving these difficulties are poorly understood due to a lack of data on healthy infants. One potential mechanism of dysphagia in adults is correlated with bolus volume. Yet, whether and how bolus volume impacts swallow safety in infant feeding is unknown. A further complication for safe infant swallowing…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:58

Revue des Maladies Respiratoires
Scanner thoracique chez l’enfant atteint de mucoviscidose : intérêt d’un protocole en expiration séquentielle pour réduire la dose d’irradiationPublication date: Available online 22 April 2020Source: Revue des Maladies RespiratoiresAuthor(s): S. Simon, C. Baunin, J. Vial, E. Mas, L. Roditis, M. Michelet, M. MittaineRevue des Maladies RespiratoiresThu Apr 23, 2020 14:25Intoxication au monoxyde de carbone chez les fumeurs actifs ou passifs de chichaPublication date: Available online 22 April 2020Source:…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:58

M
Nature Communications – current – nature.com science feedsCryo-EM structure of the PlexinC1/A39R complex reveals inter-domain interactions critical for ligand-induced activationNature Communications, Published online: 23 April 2020; doi:10.1038/s41467-020-15862-0Plexins are the receptors for the guidance molecules semaphorins and regulate immunity and the development of the nervous and cardiovascular systems. Here authors present a structure of full-length human PlexinC1 in complex with its ligand…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:57

Clinical Cases
Case Reports in OphthalmologyRifabutin-Cobicistat Drug Interaction Resulting in Severe Bilateral PanuveitisWe report a novel case of severe bilateral panuveitis with hypopyon secondary to rifabutin and cobicistat drug interaction in the setting of human immunodeficiency virus (HIV) infection and latent tuberculosis (TB). A 63-year-old woman presented with bilateral conjunctival injection and decreasing vision of 5 days’ duration. She had a history of well-controlled HIV infection, latent TB, and…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:56

Rare Cancers
Multiple cholangiocarcinomas in the intrahepatic and extrahepatic biliary tree due to dichloromethane exposure: a case report.Related ArticlesMultiple cholangiocarcinomas in the intrahepatic and extrahepatic biliary tree due to dichloromethane exposure: a case report. Surg Case Rep. 2020 Apr 21;6(1):79 Authors: Ogawa D, Hayashi H, Kitamura F, Uemura N, Miyata T, Okabe H, Imai K, Yamasita Y, Kubo S, Baba H Abstract BACKGROUND: An outbreak of cholangiocarcinoma in Japan has led to widespread concern…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:53

The association between the diesel exhaust particle exposure from bus emission and the tubular epithelial cell deformation of rats
The association between the diesel exhaust particle exposure from bus emission and the tubular epithelial cell deformation of rats: AbstractThe diesel vehicle emissions regarding particles have become a problem due to human health adversely. Especially ultrafine particles (diameter ≤ 100 nm) can deeply penetrate the human body leading to cell deformation. Investigation of the diesel ultrafine particle exposure to the cell deformation has become a challenge to build up understanding the impacts of…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:45

Contemporary Considerations in Adjuvant Radioiodine Treatment of Adults with Differentiated Thyroid Cancer
Contemporary Considerations in Adjuvant Radioiodine Treatment of Adults with Differentiated Thyroid Cancer: AbstractDifferentiated thyroid cancer (DTC) is the most common endocrine malignancy with a growing incidence worldwide. The initial conventional management is surgery, followed by consideration of 131I treatment that includes 3 options. These are termed remnant ablation (targeting benign thyroid remnant), adjuvant (targeting presumed microscopic DTC) and known disease (targeting macroscopic…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:44

Squamous cell carcinoma of the oral tongue: Distinct epidemiological profile disease
Squamous cell carcinoma of the oral tongue: Distinct epidemiological profile disease: AbstractBackgroundOral squamous cell carcinoma (OSCC) occurs in different subsites within the oral cavity. Our goal was to investigate the epidemiological features of OSCC with relation to age and subsite.MethodsRetrospective review of all patients treated for OSCC in a tertiary care center between 2000 and 2018.ResultsA total of 360 patients were included. Five age groups were defined: 0 to 30, 31 to 45, 46 to…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:44

Melanoma-associated fibroblasts impair CD8+ T cell function and modify expression of immune checkpoint regulators via increased arginase activity
Melanoma-associated fibroblasts impair CD8+ T cell function and modify expression of immune checkpoint regulators via increased arginase activity: AbstractAbstractThis study shows that melanoma-associated fibroblasts (MAFs) suppress cytotoxic T lymphocyte (CTL) activity and reveals a pivotal role played by arginase in this phenomenon. MAFs and normal dermal fibroblasts (DFs) were isolated from surgically resected melanomas and identified as Melan-A-/gp100-/FAP+ cells. CTLs of healthy blood donors…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:44

11p15.5 epimutations in children with Wilms tumor and hepatoblastoma detected in peripheral blood
11p15.5 epimutations in children with Wilms tumor and hepatoblastoma detected in peripheral blood: BackgroundConstitutional or somatic mosaic epimutations are increasingly recognized as a mechanism of gene dysregulation resulting in cancer susceptibility. Beckwith‐Wiedemann syndrome is the cancer predisposition syndrome most commonly associated with epimutation and is extremely variable in its phenotypic presentation, which can include isolated tumors. Because to the authors’ knowledge large‐scale…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:44

Pembrolizumab for the treatment of programmed death–ligand 1‒positive advanced carcinoid or pancreatic neuroendocrine tumors: Results from the KEYNOTE‐028 study
Pembrolizumab for the treatment of programmed death–ligand 1‒positive advanced carcinoid or pancreatic neuroendocrine tumors: Results from the KEYNOTE‐028 study: BackgroundDespite a protracted disease course and multiple available therapies, patients with well‐differentiated neuroendocrine tumors (NETs) inevitably experience disease progression. Programmed death–ligand 1 (PD‐L1) has been associated with NET progression and prognosis. The multicohort, phase 1 KEYNOTE‐028 study (ClinicalTrials.gov…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:43

M
Latest Results for Bulletin of Experimental Biology and MedicineParameters of Experimental Activity in the Study of the Cognitive Abilities of Rhesus Monkeys ( Macaca mulatta ) and Baboons ( Papio hamadryas )We compared experimental activity, behavioral activity in the experiment, of rhesus monkeys (Macaca mulatta) and baboons (Papio hamadryas). Baboons showed higher levels of experimental activity. The contrast in the activity between the species is probably associated with species-specific characteristics…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:43

M
BRC : Last 10 articlesSociety BulletinsBreast Care 2020;15:201–204BRC : Last 10 articles21hPharmaNewsBreast Care 2020;15:198–200BRC : Last 10 articles21hPD-L1 IC-positive Patienten im FokusBreast Care 2020;15:197–197BRC : Last 10 articles1dΣήμανση της παραπάνω ενότητας ως αναγνωσμένης Catheterization and Cardiovascular InterventionsManagement of ST‐segment‐elevation myocardial infarction during the coronavirus disease 2019 (COVID‐19) outbreak: Iranian“247” National Committee’s position paper on…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:42

Type 2 immunity in the skin and lungs
Type 2 immunity in the skin and lungs: AbstractThere has been extensive progress in understanding the cellular and molecular mechanisms of inflammation and immune regulation in allergic diseases of the skin and lungs during the last few years. Asthma and atopic dermatitis are typical diseases of type 2‐immune responses. IL‐25, IL‐33 and TSLP are essential cytokines of epithelial cell that activation by allergens, pollutants, viruses, bacteria and toxins that derive type 2 responses. Th2 cells and…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:41

Measuring vincristine-induced peripheral neuropathy in children with cancer: validation of the Dutch pediatric–modified Total Neuropathy Score
Measuring vincristine-induced peripheral neuropathy in children with cancer: validation of the Dutch pediatric–modified Total Neuropathy Score: AbstractPurposeThe aims were to evaluate the construct validity and reliability of the Dutch version of the pediatric-modified Total Neuropathy Score (ped-mTNS) for assessing vincristine-induced peripheral neuropathy (VIPN) in Dutch pediatric oncology patients aged 5–18 years.MethodsConstruct validity (primary aim) of the ped-mTNS was determined by testing…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:40

Chemotherapy-induced peripheral neuropathy (CIPN) and its treatment: an NIH Collaboratory study of claims data
Chemotherapy-induced peripheral neuropathy (CIPN) and its treatment: an NIH Collaboratory study of claims data: AbstractPurposeChemotherapy-induced peripheral neuropathy (CIPN) is a disabling complication of many chemotherapies. We investigated the feasibility of using health plan claims and administrative data to identify CIPN occurrence by comparing patients who received neurotoxic and non-neurotoxic chemotherapies.MethodsThe sample included over 53,000,000 patients from two regional and one national…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:40

Twelve cases of acneiform eruptions while on anti-CTLA4 therapy
Twelve cases of acneiform eruptions while on anti-CTLA4 therapy: AbstractWe present the first detailed report of acneiform eruptions in patients on CTLA-4 inhibitor therapy. Acneiform eruptions commonly occur (up to 75–100%) as a cutaneous adverse event associated with EGFR inhibition; however, acneiform eruptions have not been highly reported as a cutaneous adverse event associated with CTLA-4 inhibitor therapy. We conducted a retrospective chart review of our institution’s database to assess cutaneous…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:39

Oral microbial influences on oral mucositis during radiotherapy treatment of head and neck cancer
Oral microbial influences on oral mucositis during radiotherapy treatment of head and neck cancer: AbstractPurposeOral mucositis (OM) remains a significant complication developed by many patients undergoing radiotherapy (RT) to the head and neck region. Emerging data suggest oral microbes may contribute to the onset and severity of this acute side effect.MethodsIn this study, saliva and oral swabs from head and neck cancer patients undergoing RT were collected. We employed molecular microbiological…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:39

Ultrasound systems for risk stratification of thyroid nodules prompt inappropriate biopsy in autonomously functioning thyroid nodules
Ultrasound systems for risk stratification of thyroid nodules prompt inappropriate biopsy in autonomously functioning thyroid nodules: SummaryObjectiveUltrasound (US) risk stratification systems (RSSs) have been developed to reduce the number of unnecessary fine‐needle aspiration (FNA) biopsies in patients with thyroid nodules. Autonomously functioning thyroid nodules (AFTN) account for 5‐10% of palpable lesions and are very rarely malignant. The present study was undertaken to investigate how RSSs…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:38

M
AuntMinnieEurope.com HeadlinesDutch airline makes pledge on radioisotope deliveriesKLM Royal Dutch Airlines has promised to allow medical isotopes to be carried…Read more on AuntMinnieEurope.comRelated Reading: SNMMI, IAEA collaborate on training German team wins SNMMI Image of the Year award SNMMI: FET-PET could have answers for brainstem glioma SNMMI: PET/CT may help guide prostate biopsiesAuntMinnieEurope.com Headlines5mGuerbet forecasts 30%-35% drop in April salesAlthough the company posted…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:37

A complete lower lip and chin unit resurfacing with expanded cheek flaps: A modified approach with minimal influence on facial cosmetic units.
A complete lower lip and chin unit resurfacing with expanded cheek flaps: A modified approach with minimal influence on facial cosmetic units.: Related ArticlesA complete lower lip and chin unit resurfacing with expanded cheek flaps: A modified approach with minimal influence on facial cosmetic units.J Plast Reconstr Aesthet Surg. 2019 Oct;72(10):1700-1738Authors: Qiu Y, Gao W, Chen H, Ma G, Jin Y, Lin XPMID: 31444055 [PubMed – indexed for MEDLINE]

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:36

Αφαίρεση διαφημίσεων

M
Movement DisordersLower Vitamin B12 Level at Multiple System Atrophy Diagnosis Is Associated With Shorter SurvivalAbstract Background Multiple system atrophy (MSA) is a neurodegenerative disorder from α‐synuclein aggregation. in vitro studies suggest vitamin B12 may interrupt α‐synuclein‐mediated neurodegeneration. The objective of this study was to determine whether serum vitamin B12 level at MSA diagnosis is associated with survival. Methods One hundred eighty‐two MSA patients evaluated at Mayo…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:36

A Mouse Model of Oropharyngeal Papillomavirus-Induced Neoplasia Using Novel Tools for Infection and Nasal Anesthesia.
A Mouse Model of Oropharyngeal Papillomavirus-Induced Neoplasia Using Novel Tools for Infection and Nasal Anesthesia.: Related ArticlesA Mouse Model of Oropharyngeal Papillomavirus-Induced Neoplasia Using Novel Tools for Infection and Nasal Anesthesia.Viruses. 2020 Apr 16;12(4):Authors: Bilger A, King RE, Schroeder JP, Piette JT, Hinshaw LA, Kurth AD, AlRamahi RW, Barthel MV, Ward-Shaw ET, Buehler D, Masters KS, Thibeault SL, Lambert PFAbstract Human head and neck cancers that develop from…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:35

Metastatic Tumors of the Oro-Facial Tissues: Clear Cell Renal Cell Carcinoma. A Clinico-Pathological and Immunohistochemical Study of Seven Cases.
Metastatic Tumors of the Oro-Facial Tissues: Clear Cell Renal Cell Carcinoma. A Clinico-Pathological and Immunohistochemical Study of Seven Cases.: Related ArticlesMetastatic Tumors of the Oro-Facial Tissues: Clear Cell Renal Cell Carcinoma. A Clinico-Pathological and Immunohistochemical Study of Seven Cases.J Clin Med. 2020 Apr 17;9(4):Authors: Capodiferro S, Limongelli L, Mastropasqua MG, Favia G, Lajolo C, Colella G, Tempesta A, Maiorano EAbstract Metastases to orofacial tissues are infrequent,…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:35

Extensive craniospinal disseminated metastasis after the resection of intradural extramedullary ependymoma in the craniocervical junction: A case report and literature review.
Extensive craniospinal disseminated metastasis after the resection of intradural extramedullary ependymoma in the craniocervical junction: A case report and literature review.: Related ArticlesExtensive craniospinal disseminated metastasis after the resection of intradural extramedullary ependymoma in the craniocervical junction: A case report and literature review.Int J Neurosci. 2020 Apr 22;:1-8Authors: Guo Z, Wan J, Zhao BAbstract Purpose/Aim: Intradural extramedullary (IDEM) ependymomas…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:34

Low rates of airway intervention in adult supraglottitis: A case series and meta-analysis.
Low rates of airway intervention in adult supraglottitis: A case series and meta-analysis.: Related ArticlesLow rates of airway intervention in adult supraglottitis: A case series and meta-analysis.Am J Otolaryngol. 2020 Apr 04;:102482Authors: Ringel B, Shilo S, Carmel-Neiderman NN, Livneh N, Oestreicher-Kedem Y, Abergel A, Fliss DM, Horowitz GAbstract PURPOSE: Acute supraglottitis (SG) can potentially lead to rapid airway obstruction. The last few decades have witnessed a shift towards a…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:34

Transient Amnesia Following Prehospital Low-dose Ketamine Administration.
Transient Amnesia Following Prehospital Low-dose Ketamine Administration.: Related ArticlesTransient Amnesia Following Prehospital Low-dose Ketamine Administration.Am J Emerg Med. 2020 Apr 09;:Authors: Aljadeed R, Perona SAbstract Low doses of ketamine have been shown to be safe and effective for pain relief. Adverse effects are generally mild and transient. A 69-year-old woman suffered a witnessed ground-level fall without report of head injury, loss of consciousness, or intoxication. She…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:33

Clear cell lesions in pathology: Histomorphologic approach to diagnosis.
Clear cell lesions in pathology: Histomorphologic approach to diagnosis.: Related ArticlesClear cell lesions in pathology: Histomorphologic approach to diagnosis.Indian J Pathol Microbiol. 2020 Apr-Jun;63(2):177-187Authors: Kar A, Pattnaik K, Kar T, Biswal P, Mishra C, Guru LAbstract There has been remarkable progress in the field of surgical pathology; however, histomorphology has remained the most important and essential tool of the surgical pathologist in everyday practice till now. It…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:33

Sebaceous lymphadenoma of parotid gland: A case report of a unique presentation in an immunocompromised patient.
Sebaceous lymphadenoma of parotid gland: A case report of a unique presentation in an immunocompromised patient.: Related ArticlesSebaceous lymphadenoma of parotid gland: A case report of a unique presentation in an immunocompromised patient.J Family Med Prim Care. 2020 Feb;9(2):1202-1205Authors: Al-Essa MAbstract Sebaceous lymphadenoma is a rare, benign tumor of the parotid gland accounting for only 0.196% of all adenomas of the parotid gland. Our aim is to present a case of sebaceous lymphadenoma,…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:33

Stereotactic radiosurgery for head and neck paragangliomas: a systematic review and meta-analysis.
Stereotactic radiosurgery for head and neck paragangliomas: a systematic review and meta-analysis.: Related ArticlesStereotactic radiosurgery for head and neck paragangliomas: a systematic review and meta-analysis.Neurosurg Rev. 2020 Apr 21;:Authors: Fatima N, Pollom E, Soltys S, Chang SD, Meola AAbstract Head and neck paragangliomas (HNPs) are rare, usually benign hyper vascularized neuroendocrine tumors that traditionally have been treated by surgery, with or without endovascular embolization,…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:32

PI3K/AKT/mTOR pathway and autophagy regulator genes in paranasal squamous cell carcinoma metastasis.
PI3K/AKT/mTOR pathway and autophagy regulator genes in paranasal squamous cell carcinoma metastasis.: Related ArticlesPI3K/AKT/mTOR pathway and autophagy regulator genes in paranasal squamous cell carcinoma metastasis.Mol Biol Rep. 2020 Apr 21;:Authors: Biray Avci C, Sezgin B, Goker Bagca B, Karci HB, Gode SAbstract Although there are many studies on the role of PI3K/AKT/mTOR pathway and autophagy genes in the mechanism of head and neck cancer formation and prognostic significance, there…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:32

Effects of S‑adenosyl‑L‑methionine on the invasion and migration of head and neck squamous cancer cells and analysis of the underlying mechanisms.
Effects of S‑adenosyl‑L‑methionine on the invasion and migration of head and neck squamous cancer cells and analysis of the underlying mechanisms.: Related ArticlesEffects of S‑adenosyl‑L‑methionine on the invasion and migration of head and neck squamous cancer cells and analysis of the underlying mechanisms.Int J Oncol. 2020 Mar 12;:Authors: Mosca L, Minopoli M, Pagano M, Vitiello F, Carriero MV, Cacciapuoti G, Porcelli MAbstract S‑Adenosyl‑L‑methionine (AdoMet) is the principal methyl donor…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:32

Squamous cell carcinoma of the oral tongue: Distinct epidemiological profile disease.
Squamous cell carcinoma of the oral tongue: Distinct epidemiological profile disease.: Related ArticlesSquamous cell carcinoma of the oral tongue: Distinct epidemiological profile disease.Head Neck. 2020 Apr 22;:Authors: Yosefof E, Hilly O, Stern S, Bachar G, Shpitzer T, Mizrachi AAbstract BACKGROUND: Oral squamous cell carcinoma (OSCC) occurs in different subsites within the oral cavity. Our goal was to investigate the epidemiological features of OSCC with relation to age and subsite. …

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:31

An extensive sclerosing odontogenic carcinoma in mandible: a case report and literature review.
An extensive sclerosing odontogenic carcinoma in mandible: a case report and literature review.: Related ArticlesAn extensive sclerosing odontogenic carcinoma in mandible: a case report and literature review.Dentomaxillofac Radiol. 2020 Apr 22;:20190426Authors: Pakezhati S, Feng Y, Gao A, Lin Z, Huang X, Sun G, Zhang L, Wang TAbstract Sclerosing odontogenic carcinoma (SOC) is a primary intraosseous carcinoma of the jaw that was listed as a separate entity for the first time in the latest…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:31

The Prognostic Value of Circulating Inflammatory Cell Counts in Sudden Sensorineural Hearing Loss and the Effect of Cardiovascular Risk Factors…………..Elevated levels of N and NLR may be considered as strong laboratory findings showing an inflammatory response in the diagnosis of SSNHL, but the presence of CVR factors does not seem to increase the inflammatory response in SSNHL as expected. In patients with SSNHL, NLR and PLR elevation may indicate better prognosis.
The Prognostic Value of Circulating Inflammatory Cell Counts in Sudden Sensorineural Hearing Loss and the Effect of Cardiovascular Risk Factors.: Related ArticlesThe Prognostic Value of Circulating Inflammatory Cell Counts in Sudden Sensorineural Hearing Loss and the Effect of Cardiovascular Risk Factors.Ear Nose Throat J. 2020 Apr 22;:145561320920968Authors: Sancaktar ME, Ağrı İ, Çeçen AB, Akgül G, Çelebi MAbstract OBJECTIVES: Recent studies suggest that elevated neutrophil to lymphocyte…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:31

M
ChemosensorsChemosensors, Vol. 8, Pages 30: An Electronic Nose Technology to Quantify Pyrethroid Pesticide Contamination in TeaChemosensors, Vol. 8, Pages 30: An Electronic Nose Technology to Quantify Pyrethroid Pesticide Contamination in Tea Chemosensors doi: 10.3390/chemosensors8020030 Authors: Xiaoyan Tang Wenmin Xiao Tao Shang Shanyan Zhang Xiaoyang Han Yuliang Wang Haiwei Sun The contamination of tea with toxic pesticides is a major concern. Additionally, because of improved detection methods,…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:29

Ultrasonic Measurement of Lingual Artery and Its Application for Midline Glossectomy.
Ultrasonic Measurement of Lingual Artery and Its Application for Midline Glossectomy.: Related ArticlesUltrasonic Measurement of Lingual Artery and Its Application for Midline Glossectomy.Ann Otol Rhinol Laryngol. 2020 Apr 21;:3489420913581Authors: Liu C, Qin J, Xing D, Lu H, Yue R, Li S, Wu DAbstract OBJECTIVE: To explore the application of lingual artery ultrasound (US) for midline glossectomy in patients with obstructive sleep apnea (OSA). METHODS: Lingual artery US was performed…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:28

CPAP indication based on clinical data and oximetry for patients with suspicion of obstructive sleep apnea: A multicenter trial.
CPAP indication based on clinical data and oximetry for patients with suspicion of obstructive sleep apnea: A multicenter trial.: Related ArticlesCPAP indication based on clinical data and oximetry for patients with suspicion of obstructive sleep apnea: A multicenter trial.Sleep Sci. 2019 Oct-Dec;12(4):249-256Authors: Nigro CA, Borsini EE, Dibur E, Larrateguy LD, Cazaux A, Elias C, de-la-Vega M, Berrozpe C, Maggi S, Grandval S, Cambursano H, Visentini D, Criniti J, Nogueira FAbstract Background…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:26

The effect of Salvia officinalis extract on symptoms of flushing, night sweat, sleep disorders, and score of forgetfulness in postmenopausal women.
The effect of Salvia officinalis extract on symptoms of flushing, night sweat, sleep disorders, and score of forgetfulness in postmenopausal women.: Related ArticlesThe effect of Salvia officinalis extract on symptoms of flushing, night sweat, sleep disorders, and score of forgetfulness in postmenopausal women.J Family Med Prim Care. 2020 Feb;9(2):1086-1092Authors: Zeidabadi A, Yazdanpanahi Z, Dabbaghmanesh MH, Sasani MR, Emamghoreishi M, Akbarzadeh MAbstract Background: Complications of…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:26

An Electronic Nose Technology to Quantify Pyrethroid Pesticide Contamination in Tea
Chemosensors, Vol. 8, Pages 30: An Electronic Nose Technology to Quantify Pyrethroid Pesticide Contamination in Tea: Chemosensors, Vol. 8, Pages 30: An Electronic Nose Technology to Quantify Pyrethroid Pesticide Contamination in TeaChemosensors doi: 10.3390/chemosensors8020030Authors: Xiaoyan Tang Wenmin Xiao Tao Shang Shanyan Zhang Xiaoyang Han Yuliang Wang Haiwei Sun The contamination of tea with toxic pesticides is a major concern. Additionally, because of improved detection methods,…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:23

M
edoc: No conditions. Results ordered -Date Deposited.Tick-borne relapsing fever caused by Borrelia persica in Traveler to Central Asia, 2019We report a case of tick-borne relapsing fever caused by Borrelia persica in a traveler returning to Switzerland from central Asia. After the disease was diagnosed by blood smear microscopy, the causative Borrelia species was confirmed by shotgun metagenomics sequencing. PCR and sequencing techniques provide highly sensitive diagnostic tools superior to microscopy.edoc:…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:23

Αφαίρεση διαφημίσεων

Diagnostic Criteria for Primary Autoimmune Cerebellar Ataxia—Guidelines from an International Task Force on Immune-Mediated Cerebellar Ataxias
Diagnostic Criteria for Primary Autoimmune Cerebellar Ataxia—Guidelines from an International Task Force on Immune-Mediated Cerebellar Ataxias: AbstractAside from well-characterized immune-mediated ataxias with a clear trigger and/or association with specific neuronal antibodies, a large number of idiopathic ataxias are suspected to be immune mediated but remain undiagnosed due to lack of diagnostic biomarkers. Primary autoimmune cerebellar ataxia (PACA) is the term used to describe this later group….

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:22

M
Microbiological ResearchSeed biopriming with antagonistic microbes and ascorbic acid induce resistance in tomato against Fusarium wiltPublication date: Available online 23 April 2020Source: Microbiological ResearchAuthor(s): Prachi Singh, Jyoti Singh, Shatrupa Ray, Rahul Singh Rajput, Anukool Vaishnav, Rakesh Kumar Singh, Harikesh Bahadur SinghMicrobiological Research16hΣήμανση της παραπάνω ενότητας ως αναγνωσμένης Journal of Medical Case Reports – Latest ArticlesVenetoclax in combination with carfilzomib…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:21

Severe eosinophilic asthma and aspirin-exacerbated respiratory disease associated to eosinophilic gastroenteritis treated with mepolizumab: a case report
Severe eosinophilic asthma and aspirin-exacerbated respiratory disease associated to eosinophilic gastroenteritis treated with mepolizumab: a case report: Mepolizumab (MEP) is the first anti Interleukin (IL)-5 add-on therapy approved for the treatment of severe refractory eosinophilic asthma.NUCALAΜοιραστείτε Ευρετήριο ΑναφορέςΦάρμακοΕνεργά συστατικά1 Μεπολιζουμάμπη90Z2UF0E52 – MEPOLIZUMABΤρόποι και περιορισμοί διάθεσηςΠροϊόν του οποίου η κυκλοφορία γίνεται με βάση τη νομοθεσία περί φαρμάκων που…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

10:20

An unusual onset of pediatric acute lymphoblastic leukemia
An unusual onset of pediatric acute lymphoblastic leukemia: AbstractAcute lymphoblastic leukemia is the most frequent cancer in children: it represents 80% of leukemias and about 24% of all neoplasms diagnosed between 0 and 14 years. Acute lymphoblastic leukemia mainly affects children between 2 and 5 years old and in this age group the incidence is about 80–90 cases per million per year. In acute lymphoblastic leukemia, cancer cells multiply rapidly and accumulate in the bone marrow and subsequently…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:58

Tinnitus distress targeted the frequency bands beta3 (23.5–35 Hz) and gamma (35.5–45 Hz) in right frontal regions, whereas delta (0.5–4 Hz) exhibited significant changes in temporal-parietal sources. Further, 57.8% of the total variance in EEG power was subject-specific and acknowledged by the LMM framework and its prediction.
Accounting for Heterogeneity: Mixed-Effects Models in Resting-State EEG Data in a Sample of Tinnitus Sufferers: AbstractIn neuroscience, neural oscillations and other features of brain activity recorded by electroencephalography (EEG) are typically statistically assessed on the basis of the study’s population mean to identify possible blueprints for healthy subjects, or subjects with diagnosable neurological or psychiatric disorders. Despite some inter-individual similarities, there is reason to…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:57

Accounting for Heterogeneity: Mixed-Effects Models in Resting-State EEG Data in a Sample of Tinnitus Sufferers
Accounting for Heterogeneity: Mixed-Effects Models in Resting-State EEG Data in a Sample of Tinnitus Sufferers: AbstractIn neuroscience, neural oscillations and other features of brain activity recorded by electroencephalography (EEG) are typically statistically assessed on the basis of the study’s population mean to identify possible blueprints for healthy subjects, or subjects with diagnosable neurological or psychiatric disorders. Despite some inter-individual similarities, there is reason to…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:57

M
edoc: No conditions. Results ordered -Date Deposited.Structure-activity relationship of antischistosomal ozonide carboxylic acidsSemisynthetic artemisinins and other bioactive peroxides are best known for their powerful antimalarial activities, and they also show substantial activity against schistosomes-another hemoglobin-degrading pathogen. Building on this discovery, we now describe the initial structure-activity relationship (SAR) of antischistosomal ozonide carboxylic acids OZ418 (; 2; ) and…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:56

M
Latest ResultsDistrict heating networks: an inter-comparison of environmental indicatorsAbstract The installation of district heating (DH) systems constitutes an advantage from the energetic, climate, and air quality aspects. However, the configuration and operational features of a DH system affect significantly its environmental performance. The objective of the present study is the energetic and environmental assessment of DH networks that present differences in size and operating configurations,…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:54

miR-1199-5p and Zeb1 function in a double-negative feedback loop potentially coordinating EMT and tumour metastasis
miR-1199-5p and Zeb1 function in a double-negative feedback loop potentially coordinating EMT and tumour metastasis: Epithelial tumour cells can gain invasive and metastatic capabilities by undergoing an epithelial-mesenchymal transition. Transcriptional regulators and post-transcriptional effectors like microRNAs orchestrate this process of high cellular plasticity and its malignant consequences. Here, using microRNA sequencing in a time-resolved manner and functional validation, we have identified…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:53

Cerebral Corpora amylacea are dense membranous labyrinths containing structurally preserved cell organelles
Cerebral Corpora amylacea are dense membranous labyrinths containing structurally preserved cell organelles: Corpora amylacea are cell-derived structures that appear physiologically in the aged human brain. While their histological identification is straightforward, their ultrastructural composition and microenvironment at the nanoscale have remained unclear so far, as has their relevance to aging and certain disease states that involve the sequestration of toxic cellular metabolites. Here, we apply…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:52

M
Journal of Medical Genetics current issueGenetic variability and potential effects on clinical trial outcomes: perspectives in Parkinsons diseaseBackgroundClassical randomisation of clinical trial patients creates a source of genetic variance that may be contributing to the high failure rate seen in neurodegenerative disease trials. Our objective was to quantify genetic difference between randomised trial arms and determine how imbalance can affect trial outcomes. Methods5851 patients with Parkinson’s…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:51

Brentuximab vedotin treatment associated with acute and chronic inflammatory demyelinating polyradiculoneuropathies
Brentuximab vedotin treatment associated with acute and chronic inflammatory demyelinating polyradiculoneuropathies: IntroductionBrentuximab vedotin (BV) is an antibody-drug conjugate composed by an anti-CD30 monoclonal antibody and the anti-microtubule agent monomethyl auristatin E, used for the treatment of relapsed/refractory Hodgkin’s lymphoma and non-Hodgkin’s lymphoma.Peripheral neuropathy is a frequent adverse event of BV treatment, affecting up to 60% to 70% of patients.1 It usually consists…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:51

CircRNAs in Oral Cancer
Cancers, Vol. 12, Pages 1041: Functional and Clinical Impact of CircRNAs in Oral Cancer: Cancers, Vol. 12, Pages 1041: Functional and Clinical Impact of CircRNAs in Oral CancerCancers doi: 10.3390/cancers12041041Authors: Ion Cristóbal Cristina Caramés Jaime Rubio Marta Sanz-Alvarez Melani Luque Juan Madoz-Gúrpide Federico Rojo Jesús García-Foncillas The increasing number of recently published works regarding the role of circular RNAs (circRNAs) in oral cancer highlights the…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:50

2-deoxy-2[F-18] fluoro-d-glucose positron emission tomography Deauville scale and core-needle biopsy to determine successful management after six doxorubicin, bleomycin, vinblastine and dacarbazine cycles in advanced-stage Hodgkin lymphoma
2-deoxy-2[F-18] fluoro-<span class="small-caps">d-glucose positron emission tomography</span> Deauville scale and core-needle biopsy to determine successful management after six doxorubicin, bleomycin, vinblastine and dacarbazine cycles in advanced-stage Hodgkin lymphoma: Publication date: June 2020Source: European Journal of Cancer, Volume 132Author(s): M. Picardi, R. Fonti, R. Della Pepa, C. Giordano, N. Pugliese, E. Nicolai, M. Salvatore, C. Mainolfi, P. Venetucci, M.G. Rascato, I….

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:49

Cornelia de Lange syndrome: from molecular diagnosis to therapeutic approach
Cornelia de Lange syndrome: from molecular diagnosis to therapeutic approach: Cornelia de Lange syndrome (CdLS) is a severe genetic disorder characterised by multisystemic malformations. CdLS is due to pathogenetic variants in NIPBL, SMC1A, SMC3, RAD21 and HDAC8 genes which belong to the cohesin pathway. Cohesin plays a pivotal role in chromatid cohesion, gene expression, and DNA repair. In this review, we will discuss how perturbations in those biological processes contribute to CdLS phenotype and…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:48

M
ScienceDirect Publication: Biochimica et Biophysica Acta (BBA) – Molecular Cell ResearchUbiquitin-dependent proteasomal degradation of AMPK gamma subunit by Cereblon inhibits AMPK activityPublication date: Available online 22 April 2020Source: Biochimica et Biophysica Acta (BBA) – Molecular Cell ResearchAuthor(s): Seung-Joo Yang, Seung-Je Jeon, Thang Van Nguyen, Raymond J. Deshaies, Chul-Seung Park, Kwang Min LeeScienceDirect Publication: Biochimica et Biophysica Acta (BBA) – Molecular Cell Research10hΣήμανση…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:47

Prevalence of Lymphoid Neoplasia in a Retrospective Analysis of Warthin Tumor: A Single Institution Experience
Prevalence of Lymphoid Neoplasia in a Retrospective Analysis of Warthin Tumor: A Single Institution Experience: AbstractWarthin tumor is one of the most common benign salivary gland tumors. Overt lymphoma is known to occur in the lymphoid stroma of Warthin tumor. In situ follicular neoplasia is difficult to identify in routine histologic examination of lymphoid tissue and has not been reported in association with Warthin tumor. Our objective is to determine the prevalence of overt malignant lymphoma…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:45

Congenital Conditions of Hypophosphatemia in Children
Congenital Conditions of Hypophosphatemia in Children: AbstractGreat strides over the past few decades have increased our understanding of the pathophysiology of hypophosphatemic disorders. Phosphate is critically important to a variety of physiologic processes, including skeletal growth, development and mineralization, as well as DNA, RNA, phospholipids, and signaling pathways. Consequently, hypophosphatemic disorders have effects on multiple systems, and may cause a variety of nonspecific signs…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:45

M
Latest Results for Drugs in RAn Ex Vivo Evaluation of Cenobamate Administered via Enteral TubesAbstract Background Cenobamate is a new, Food and Drug Administration (FDA)-approved oral antiepileptic drug for treatment of focal seizures in adults. This study examined recovery of cenobamate from suspensions administered through ex vivo enteral feeding tubes. Methods Suspensions containing 100 and 200 mg of cenobamate were prepared (five duplicates for…Latest Results for Drugs in R5hΣήμανση της παραπάνω…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:45

The VEGFR kinase inhibitor vatalanib in combination with the mTOR inhibitor, everolimus, in patients with advanced solid tumors
A phase I study of the VEGFR kinase inhibitor vatalanib in combination with the mTOR inhibitor, everolimus, in patients with advanced solid tumors: SummaryPurpose Combining small-molecule inhibitors of different targets was shown to be synergistic in preclinical studies. Testing this concept in clinical trials is, however, daunting due to challenges in toxicity management and efficacy assessment. This study attempted to evaluate the safety and efficacy of vatalanib plus everolimus in patients with…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:43

Αφαίρεση διαφημίσεων

M
Advances in TherapyThe Impact of Patient Support Programs on Adherence to Disease-Modifying Therapies of Patients with Relapsing-Remitting Multiple Sclerosis in Germany: A Non-Interventional, Prospective StudyAbstract Introduction Disease-modifying therapies (DMTs) in multiple sclerosis (MS) are chronic therapies, and patients are likely to face challenges in adhering to DMT dosing regimens over time. DMT manufacturers offer patient support programs (PSPs) to increase adherence. PSPs are managed…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:41

Stromal platelet-derived growth factor receptor-{beta} signaling promotes breast cancer metastasis in the brain
Stromal platelet-derived growth factor receptor-{beta} signaling promotes breast cancer metastasis in the brain: Platelet-derived growth factor receptor-beta (PDGFRβ) is a receptor tyrosine kinase found in cells of mesenchymal origin such as fibroblasts and pericytes. Activation of this receptor is dependent on paracrine ligand induction, and its preferred ligand PDGFB is released by neighboring epithelial and endothelial cells. While expression of both PDGFRβ and PDGFB has been noted in patient…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:38

High rate incidence of post-surgical adverse events in patients with low-risk papillary thyroid cancer who did not accept active surveillance
High rate incidence of post-surgical adverse events in patients with low-risk papillary thyroid cancer who did not accept active surveillance: AbstractPurposeTo describe the outcomes and the incidence of adverse events following active surveillance (AS) versus immediate surgery in patients with low-risk papillary thyroid carcinoma (PTC).MethodsWe prospectively evaluated 286 patients who attended the Hospital de Clínicas, with a single thyroid nodule <1.5 cm classified as Bethesda category V or…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:37

Thyroid function and lipid profile in euthyroid adults: the TCLSIH cohort study
Thyroid function and lipid profile in euthyroid adults: the TCLSIH cohort study: AbstractPurposeThyroid hormones (THs) have multiple effects on lipid synthesis, mobilization, and degradation, suggesting that THs may affect the development of dyslipidemia. However, prospective studies on the association between serum THs levels and incident dyslipidemia in euthyroid subjects are limited. Therefore, we conducted a cohort study (~5-year follow-up period, median: 3.0 years) to explore whether THs can…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:37

Swallow Safety is Determined by Bolus Volume During Infant Feeding in an Animal Model
Swallow Safety is Determined by Bolus Volume During Infant Feeding in an Animal Model: AbstractFeeding difficulties are especially prevalent in preterm infants, although the mechanisms driving these difficulties are poorly understood due to a lack of data on healthy infants. One potential mechanism of dysphagia in adults is correlated with bolus volume. Yet, whether and how bolus volume impacts swallow safety in infant feeding is unknown. A further complication for safe infant swallowing is recurrent…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:36

Rare case of basilar artery aneurysm in a young child
Rare case of basilar artery aneurysm in a young child: A previously well, 14-month-old girl presented with acute decreased level of consciousness. There was no history of trauma, systemic upset or significant family history. Blood pressure was within normal range and no focal neurological deficit was elicited on examination. Neuroimaging revealed a subarachnoid haemorrhage secondary to a basilar tip aneurysm. Patient underwent endovascular embolisation with good clinical outcome. Follow-up MRI revealed…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:35

Ovoid palatal patch: a clue to anti-TIF1{gamma} dermatomyositis
Ovoid palatal patch: a clue to anti-TIF1{gamma} dermatomyositis: An 80-year-old woman presented with a several-year history of progressive hair loss and scalp pruritus. No other rashes or muscle weakness were noted on examination. Scalp biopsy showed interface dermatitis, dense perivascular and periadnexal lymphocytic infiltrate, mucin and scarring alopecia. Laboratory analysis did not show evidence of myositis. The patient was started on hydroxychloroquine for possible cutaneous lupus erythematosus….

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:35

Developing Classifications of Laryngeal Dysplasia: The Historical Basis
Developing Classifications of Laryngeal Dysplasia: The Historical Basis: AbstractDuring the last 60 years numerous significant attempts have been made to achieve a widely acceptable terminology and histological grading for laryngeal squamous intraepithelial lesions. While dysplasia was included in the pathology of the uterine cervix already in 1953, the term dysplasia was accepted in laryngeal pathology first after the Toronto Centennial Conference on Laryngeal Cancer in 1974. In 1963 Kleinsasser…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:34

M
Hindawi Publishing CorporationIsoniazid and Rifampicin Produce Hepatic Fibrosis through an Oxidative Stress-Dependent MechanismBackground & Aims. Chronic hepatitis (CH) has emerged as a distinct outcome of drug-induced liver injury (DILI). Combination therapy of Isoniazid (INH) and Rifampicin (RMP) which is widely used for prolonged periods can cause acute hepatotoxicity and has been also incriminated in chronic DILI. We sought evidence of the production of hepatic fibrosis on long-term INH-RMP…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:33

Association between Lymph Node Status and Expression Levels of Androgen Receptor, miR-185, miR-205, and miR-21 in Breast Cancer Subtypes
Association between Lymph Node Status and Expression Levels of Androgen Receptor, miR-185, miR-205, and miR-21 in Breast Cancer Subtypes: Breast cancer is the most commonly diagnosed cancer among women. Difficulties in treating breast cancer are associated with the occurrence of metastases at early stages of disease, leading to its further progression. Recent studies have shown that changes in androgen receptor (AR) and microRNAs’ expressions are associated with mammary gland carcinogenesis, in particular,…

Medicine by Alexandros G. Sfakianakis

09:30

M
Latest ResultsHyperspectral inversion of mercury in reed leaves under different levels of soil mercury contaminationAbstract High mercury (Hg) affects biochemical-physiological characteristics of plant leaves such as leaf chlorophyll, causing refractive discontinuity and modifications in leaf spectra. Furthermore, the hyperspectroscopy provides a potential tool for fast non-destructive estimation of leaf Hg. However, there are few studies that have investigated Hg for wetland plants via hyperspectral…

Medicine by Alexandros G. Sfakianakis

09:27

Elevated Expression of C-Type Lectin Domain Family 5-Member A (CLEC5A) and Its Relation to Inflammatory Parameters and Disease Course in Adult-Onset Still’s Disease
Still’s disease is a type of inflammatory arthritis that causes fevers, rashes, and inflammation of joints and, sometimes, internal organs.Oct 23, 2018Still’s Disease: Symptoms, Causes, Diagnosis, TreatmentElevated Expression of C-Type Lectin Domain Family 5-Member A (CLEC5A) and Its Relation to Inflammatory Parameters and Disease Course in Adult-Onset Still’s Disease: C-type lectin domain family 5-member A (CLEC5A) associates with adaptor DAP12 (DNAX activation protein 12) to form receptor complexes…

Medicine by Alexandros G. Sfakianakis

09:26

Streptococcus pseudoporcinus: Case Reports and Review of the Literature
Streptococcus pseudoporcinus: Case Reports and Review of the Literature: Streptococcus pseudoporcinus is a beta-hemolytic Gram-positive, catalase-negative, nonmotile coccus arranged in short chains, usually found in the female genitourinary tract and differentiated from Streptococcus porcinus in 2006. Only two human infections associated with this organism have been reported to date: one in a patient with a first digit wound infection and another with lower extremity cellulitis. We describe two novel…

Medicine by Alexandros G. Sfakianakis

09:25

l -Carnitine and vitamin E ameliorate cardiotoxicity induced by tilmicosin in rats
l -Carnitine and vitamin E ameliorate cardiotoxicity induced by tilmicosin in rats: AbstractThe present study aimed to investigate the possible mitigating effect of l-carnitine (LC) and/or α-tocopherol (Vit. E) administration against tilmicosin (TIL)-induced cardiotoxicity in rats. Fifty-six male albino rats were divided into seven groups according to LC, Vit. E, and/or TIL administration. Control, LC, and Vit. E groups were given saline, 150 mg LC/kg body weight (BW)/day and 100 mg Vit. E/kg BW/day,…

Medicine by Alexandros G. Sfakianakis

09:23

#
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia,

Telephone consultation 11855 int 1193,

Medicine by Alexandros G. Sfakianakis

Medicine by Alexandros G. Sfakianakis

Medicine by Alexandros G. Sfakianakis,
RCNull Cell Adenoma of the Pituitary: Pseudo-rosettes Say It Best When Immunohistochemistry Says Nothing At All!Related ArticlesNull Cell Adenoma of the Pituitary: Pseudo-rosettes Say It Best When Immunohistochemistry Says Nothing At All! Head Neck Pathol. 2019 Dec;13(4):677-680 Authors: Singh V, Gupta K, Salunke P, Dhandapani SS Abstract Null cell adenoma is composed of adenohypophyseal cells that show no evidence of any specific cell type differentiation by immunohistochemistry or transcription…

Medicine by Alexandros G. Sfakianakis

Wed Apr 22, 2020 10:05

Head and neck squamous cell cancer associated with lymphoproliferative malignancies is aggressive.
Head and neck squamous cell cancer associated with lymphoproliferative malignancies is aggressive.: Related ArticlesHead and neck squamous cell cancer associated with lymphoproliferative malignancies is aggressive.J Laryngol Otol. 2020 Apr 20;:1-3Authors: Li L, Hamilton L, Montgomery J, Stewart MAbstract BACKGROUND: Patients with non-Hodgkin’s lymphoma and chronic lymphocytic leukaemia are at an elevated risk of further malignancy. Head and neck squamous cell carcinoma often presents with…

Medicine by Alexandros G. Sfakianakis

Wed Apr 22, 2020 09:54

Potential of Pembrolizumab in Metastatic or Recurrent Head and Neck Cancer: Evidence to Date.
Potential of Pembrolizumab in Metastatic or Recurrent Head and Neck Cancer: Evidence to Date.: Related ArticlesPotential of Pembrolizumab in Metastatic or Recurrent Head and Neck Cancer: Evidence to Date.Onco Targets Ther. 2020;13:3047-3059Authors: McCusker MG, Orkoulas-Razis D, Mehra RAbstract Relapsed and/or metastatic head and neck squamous cell carcinoma (R/M HNSCC) is a heterogeneous disease previously associated with poor prognosis and limited treatment options until the advent and…

Medicine by Alexandros G. Sfakianakis

Wed Apr 22, 2020 09:54

Chronic and Severe Non-Lichenoid Oral Ulcers Induced by Nivolumab – Diagnostic and Therapeutic Challenge: A Case Report.
Chronic and Severe Non-Lichenoid Oral Ulcers Induced by Nivolumab – Diagnostic and Therapeutic Challenge: A Case Report.: Related ArticlesChronic and Severe Non-Lichenoid Oral Ulcers Induced by Nivolumab – Diagnostic and Therapeutic Challenge: A Case Report.Case Rep Oncol. 2020 Jan-Apr;13(1):314-320Authors: Cardona AF, Ruiz-Patiño A, Ricaurte L, Zatarain-Barrón ZL, Barrón F, Arrieta OAbstract Due to the widespread use of immune checkpoint inhibitors and the growing research efforts in this…

Medicine by Alexandros G. Sfakianakis

Wed Apr 22, 2020 09:54

The Carit Maneuver: A Novel Approach for the Relief of Shoulder Dystocia-A Case Series.
The Carit Maneuver: A Novel Approach for the Relief of Shoulder Dystocia-A Case Series.: https://www.researchgate.net/publication/340673646_The_Carit_Maneuver_A_Novel_Approach_for_the_Relief_of_Shoulder_Dystocia-A_Case_Series/fulltext/5e99732d4585150839e3ba09/The-Carit-Maneuver-A-Novel-Approach-for-the-Relief-of-Shoulder-Dystocia-A-Case-Series.pdfRelated ArticlesThe Carit Maneuver: A Novel Approach for the Relief of Shoulder Dystocia-A Case Series.AJP Rep. 2020 Apr;10(2):e133-e138Authors: Gei AF,…

Medicine by Alexandros G. Sfakianakis

Wed Apr 22, 2020 09:53

Risk of head and neck cancer after chronic pancreatitis.
Risk of head and neck cancer after chronic pancreatitis.: Related ArticlesRisk of head and neck cancer after chronic pancreatitis.Ann Transl Med. 2020 Mar;8(5):213Authors: Chen CH, Chen CH, Lin CL, Hsu CY, Kao CHAbstractBackground: To evaluate the relation of head and neck cancer to chronic pancreatitis by analyzing Taiwan’s National Health Insurance Research Database.Methods: We identified 11,237 patients with chronic pancreatitis as the case cohort, which was propensity score matched with another…

Medicine by Alexandros G. Sfakianakis

Wed Apr 22, 2020 09:50

Comparison of Systemic EBV-positive T-Cell and NK-Cell Lymphoproliferative Diseases of Childhood Based on Classification Evolution: New Classification, Old Problems
Comparison of Systemic EBV-positive T-Cell and NK-Cell Lymphoproliferative Diseases of Childhood Based on Classification Evolution: New Classification, Old Problems: Systemic Epstein-Barr virus–positive T-cell and natural killer (NK)-cell lymphoproliferative diseases of childhood are a group of lethal diseases mostly affecting children and young adults. The Ohshima Grading System and the 2017 World Health Organization (WHO) classification have been used for classifying this spectrum, but these systems…

Medicine by Alexandros G. Sfakianakis

Wed Apr 22, 2020 09:42

Follicular Thyroid Neoplasms: Comparison of Clinicopathologic and Molecular Features of Atypical Adenomas and Follicular Thyroid Carcinomas
Follicular Thyroid Neoplasms: Comparison of Clinicopathologic and Molecular Features of Atypical Adenomas and Follicular Thyroid Carcinomas: In follicular thyroid neoplasms without invasion, a diagnosis of atypical adenoma (AA) (follicular tumor of uncertain malignant potential) may be rendered if atypical features (indefinite capsular/vascular invasion, necrosis, solid growth, increased mitoses) are present. This study compares clinical, histologic, and molecular features of patients with AAs (n=31),…

Medicine by Alexandros G. Sfakianakis

Wed Apr 22, 2020 09:41

Primary Vascular Tumors of Bone: A Monoinstitutional Morphologic and Molecular Analysis of 427 Cases With Emphasis on Epithelioid Variants
Primary Vascular Tumors of Bone: A Monoinstitutional Morphologic and Molecular Analysis of 427 Cases With Emphasis on Epithelioid Variants: Recent molecular discoveries have refined vascular bone tumor classification. To investigate the clinical relevance of these refinements, we reviewed all cases of primary vascular bone tumors treated at our Institute. On the basis of morphology, cases were assessed immunohistochemically and molecularly. A total of 427 cases of primary vascular tumor of bone with…

Medicine by Alexandros G. Sfakianakis

Wed Apr 22, 2020 09:41

Pregnancy-associated Inflammatory Myofibroblastic Tumors of the Uterus Are Clinically Distinct and Highly Enriched for TIMP3-ALK and THBS1-ALK Fusions
Pregnancy-associated Inflammatory Myofibroblastic Tumors of the Uterus Are Clinically Distinct and Highly Enriched for TIMP3-ALK and THBS1-ALK Fusions: As inflammatory myofibroblastic tumors (IMTs) have become more widely recognized in the female genital tract, an intriguing subset of uterine tumors associated with pregnancy has emerged. Whether uterine IMTs occurring in the setting of pregnancy are clinically or biologically distinct from other uterine IMTs is unknown. Furthermore, little is known…

Medicine by Alexandros G. Sfakianakis

Wed Apr 22, 2020 09:41

Primary Cutaneous CD4+ Small/Medium T-Cell Lymphoproliferative Disorders: A Clinical, Pathologic, and Molecular Study of 60 Cases Presenting With a Single Lesion: A Multicenter Study of the French Cutaneous Lymphoma Study Group
Primary Cutaneous CD4+ Small/Medium T-Cell Lymphoproliferative Disorders: A Clinical, Pathologic, and Molecular Study of 60 Cases Presenting With a Single Lesion: A Multicenter Study of the French Cutaneous Lymphoma Study Group: Primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder (PCSMLPD) is a recently recognized entity in the 2017 World Health Organization (WHO) classification. It belongs to the T-follicular helper (TFH) lymphoproliferations. The clinical, pathologic, and molecular…

Medicine by Alexandros G. Sfakianakis

Wed Apr 22, 2020 09:41

Prostatic Metaplasia of the Vagina and Uterine Cervix: An Androgen-associated Glandular Lesion of Surface Squamous Epithelium
Prostatic Metaplasia of the Vagina and Uterine Cervix: An Androgen-associated Glandular Lesion of Surface Squamous Epithelium: Prostatic-type differentiation in the lower female genital tract is encountered rarely and its causes and clinical associations are not well established. Within the vagina, reports to date have invariably described ectopic prostatic-type differentiation as restricted to the lamina propria. We recently encountered a patient receiving testosterone for gender dysphoria whose…

Medicine by Alexandros G. Sfakianakis

Wed Apr 22, 2020 09:40

A Modified Histopathologic Staging in Penile Squamous Cell Carcinoma Predicts Nodal Metastasis and Outcome Better Than the Current AJCC Staging
A Modified Histopathologic Staging in Penile Squamous Cell Carcinoma Predicts Nodal Metastasis and Outcome Better Than the Current AJCC Staging: Recently, the American Joint Committee on Cancer (AJCC) updated the staging system for penile squamous cell carcinoma. According to it, unlike its previous version, the involvement of urethra does not upstage the tumor; however, the involvement of corpora cavernosa (CC) does. The tumors involving CC are now staged pT3, whereas those involving corpora spongiosa…

Medicine by Alexandros G. Sfakianakis

Wed Apr 22, 2020 09:40

Gastrointestinal Malakoplakia: Clinicopathologic Analysis of 26 Cases
Gastrointestinal Malakoplakia: Clinicopathologic Analysis of 26 Cases: Malakoplakia is an inflammatory process related to defective macrophage response to bacterial infection. To further characterize the clinicopathologic manifestations of gastrointestinal malakoplakia, 26 cases were identified from 6 institutions. Hematoxylin and eosin-stained slides and available stains were reviewed, and pertinent clinicopathologic features analyzed. Sixteen patients were women (62%). Mean patient age was 64 (range:…

Medicine by Alexandros G. Sfakianakis

Wed Apr 22, 2020 09:40

Comparison of Systemic EBV-positive T-Cell and NK-Cell Lymphoproliferative Diseases of Childhood Based on Classification Evolution: New Classification, Old Problems
Comparison of Systemic EBV-positive T-Cell and NK-Cell Lymphoproliferative Diseases of Childhood Based on Classification Evolution: New Classification, Old Problems: Systemic Epstein-Barr virus–positive T-cell and natural killer (NK)-cell lymphoproliferative diseases of childhood are a group of lethal diseases mostly affecting children and young adults. The Ohshima Grading System and the 2017 World Health Organization (WHO) classification have been used for classifying this spectrum, but these systems…

Medicine by Alexandros G. Sfakianakis

Wed Apr 22, 2020 09:39

Apocrine Variant of Pleomorphic Lobular Carcinoma In Situ: Further Clinical, Histopathologic, Immunohistochemical, and Molecular Characterization of an Emerging Entity
Apocrine Variant of Pleomorphic Lobular Carcinoma In Situ: Further Clinical, Histopathologic, Immunohistochemical, and Molecular Characterization of an Emerging Entity: To date, the apocrine variant of lobular carcinoma in situ (AP-LCIS) has been cursorily described as a subtype of lobular carcinoma in situ (LCIS). We retrospectively reviewed 34 cases of AP-LCIS (including 23 associated with invasive lobular carcinoma) to fully characterize it. AP-LCIS typically presented with screen-detected calcifications…

Medicine by Alexandros G. Sfakianakis

Wed Apr 22, 2020 09:39

Skin-Colored Nodule on the Cutaneous Lip: Challenge
Skin-Colored Nodule on the Cutaneous Lip: Challenge:

Medicine by Alexandros G. Sfakianakis

Wed Apr 22, 2020 09:38

A Fatal Infection With Subtle and Nonspecific Signs and Symptoms in a Neonate: Challenge
A Fatal Infection With Subtle and Nonspecific Signs and Symptoms in a Neonate: Challenge:

Medicine by Alexandros G. Sfakianakis

Wed Apr 22, 2020 09:36

Brownish and Indurated Plaques With Yellowish Papules: Challenge
Brownish and Indurated Plaques With Yellowish Papules: Challenge: No abstract available

Medicine by Alexandros G. Sfakianakis

Wed Apr 22, 2020 09:34

M
AUD : Last 20 articlesEffect of Noise Exposure on 1,382 Metallurgical Workers in Periodic Audiometric Evaluation: A Cohort StudyIntroduction: Noise-induced hearing loss is the most preventable cause of auditory impairment. Periodic audiometric evaluations are essential to monitor the hearing health of noise-exposed workers. Objective: To compare the evolution of audiometric thresholds in the initial three evaluations at frequencies of 3, 4, and 6 kHz in groups of workers exposed or not to noise….

Medicine by Alexandros G. Sfakianakis

Wed Apr 22, 2020 09:33

M
pubmed: sleepInvestigation and diagnostic imaging of suspected pulmonary embolism during pregnancy and the puerperium: A review of the literature.Related ArticlesInvestigation and diagnostic imaging of suspected pulmonary embolism during pregnancy and the puerperium: A review of the literature. J Med Imaging Radiat Oncol. 2020 Apr 20;: Authors: Tester J, Hammerschlag G, Irving L, Pascoe D, Rees M Abstract Pulmonary embolism (PE) is a leading cause of maternal mortality with women at increased risk…

Medicine by Alexandros G. Sfakianakis

Wed Apr 22, 2020 09:32

M
AA pubmed: head and neckOsteopromotive carbon dots promote bone regeneration through the PERK-eIF2α-ATF4 pathway.Related ArticlesOsteopromotive carbon dots promote bone regeneration through the PERK-eIF2α-ATF4 pathway. Biomater Sci. 2020 Apr 20;: Authors: Jin N, Jin N, Wang Z, Liu L, Meng L, Li D, Li X, Zhou D, Liu J, Bu W, Sun H, Yang B Abstract Bone defects are still an unsolved clinical issue that must be overcome. Carbon dots have shown very promising effects in biological therapy. In the current…

Medicine by Alexandros G. Sfakianakis

Wed Apr 22, 2020 09:31

M
pubmed: philosophy for medic…Long-term outcomes after childhood convulsive status epilepticus.Related ArticlesLong-term outcomes after childhood convulsive status epilepticus. Curr Opin Pediatr. 2019 12;31(6):763-768 Authors: Pujar S, Scott RC Abstract PURPOSE OF REVIEW: It is widely accepted that childhood convulsive status epilepticus (CSE) has associated short-term and long-term mortality and morbidity. However, the role of CSE itself on subsequent adverse outcomes is still debated. In addition,…

Medicine by Alexandros G. Sfakianakis

Wed Apr 22, 2020 09:29

M
ScienceDirect Publication: Cell ReportsBeta-Catenin Causes Adrenal Hyperplasia by Blocking Zonal TransdifferentiationPublication date: 21 April 2020Source: Cell Reports, Volume 31, Issue 3Author(s): Emanuele Pignatti, Sining Leng, Yixing Yuchi, Kleiton S. Borges, Nick A. Guagliardo, Manasvi S. Shah, Gerard Ruiz-Babot, Dulanjalee Kariyawasam, Makoto Mark Taketo, Ji Miao, Paula Q. Barrett, Diana L. Carlone, David T. BreaultScienceDirect Publication: Cell Reports18hProfiling of Small Ribosomal Subunits…

Medicine by Alexandros G. Sfakianakis

Wed Apr 22, 2020 09:27

M
edoc: No conditions. Results ordered -Date Deposited.The ABC taxonomy for medication adherence translated into French and GermanWe translated the ABC adherence taxonomy (i.e., seven terms and their corresponding definitions) published by Vrijens et al. (2012) into French (F) and German (G) without changing the original meaning with the aim to promote a standardised taxonomy for medication adherence to French- and German-speaking researchers and clinicians.; A Delphi survey was performed. To generate…

Medicine by Alexandros G. Sfakianakis

Wed Apr 22, 2020 09:26

M
Emergency Medicine Journal Online FirstPrognostic accuracy of the quick Sequential Organ Failure Assessment (qSOFA)-lactate criteria for mortality in adults with suspected bacterial infection in the emergency department of a hospital with limited resourcesBackgroundRoutine use of the Sequential Organ Failure Assessment (SOFA) score to prognosticate patients with sepsis is challenged by the requirement to perform numerous laboratory tests. The prognostic accuracy of the quick SOFA (qSOFA) without…

Medicine by Alexandros G. Sfakianakis

Wed Apr 22, 2020 09:25

Mark above section as read

Medicine by Alexandros G. Sfakianakis

Medicine by Alexandros G. Sfakianakis,
RCNull Cell Adenoma of the Pituitary: Pseudo-rosettes Say It Best When Immunohistochemistry Says Nothing At All!Related ArticlesNull Cell Adenoma of the Pituitary: Pseudo-rosettes Say It Best When Immunohistochemistry Says Nothing At All! Head Neck Pathol. 2019 Dec;13(4):677-680 Authors: Singh V, Gupta K, Salunke P, Dhandapani SS Abstract Null cell adenoma is composed of adenohypophyseal cells that show no evidence of any specific cell type differentiation by immunohistochemistry or transcription…

Medicine by Alexandros G. Sfakianakis

Wed Apr 22, 2020 10:05

Mark above section as read

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Medicine by Alexandros G. Sfakianakis,
RCNull Cell Adenoma of the Pituitary: Pseudo-rosettes Say It Best When Immunohistochemistry Says Nothing At All!Related ArticlesNull Cell Adenoma of the Pituitary: Pseudo-rosettes Say It Best When Immunohistochemistry Says Nothing At All! Head Neck Pathol. 2019 Dec;13(4):677-680 Authors: Singh V, Gupta K, Salunke P, Dhandapani SS Abstract Null cell adenoma is composed of adenohypophyseal cells that show no evidence of any specific cell type differentiation by immunohistochemistry or transcription…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Wed Apr 22, 2020 10:05

Mark above section as read

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

M
Cancer MedicineGatekeeping in cancer clinical trials in Canada: The ethics of recruiting the “ideal” patientThe judgments of healthcare professionals may negatively influence equitable access and recruitment to clinical cancer trials, especially for patient populations marginalized by factors such as geography, poverty, mental health/addiction, immigration status, and language. Systems‐level strategies are needed to address the barriers that constrain ethical recruitment to clinical trials. Abstract…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:12

Association between polycystic ovary syndrome and the vaginal microbiome: a case‐control study
Association between polycystic ovary syndrome and the vaginal microbiome: a case‐control study: SummaryBackgroundPolycystic ovary syndrome (PCOS) is the most common endocrinopathy in women of reproductive age. Some evidence suggests that dysbiosis of the gut microbiota could be associated with PCOS clinical parameters, but little is known for the association between vaginal microbiome and PCOS.ObjectiveTo determine differences in the vaginal microbiome between women with PCOS and healthy control…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:11

Airborne transmission of severe acute respiratory syndrome coronavirus‐2 to healthcare workers: a narrative review
Airborne transmission of severe acute respiratory syndrome coronavirus‐2 to healthcare workers: a narrative review: SummaryHealthcare workers are at risk of infection during the severe acute respiratory syndrome (SARS) coronavirus‐2 (SARS‐CoV‐2) pandemic. International guidance suggests direct droplet transmission is likely and airborne transmission occurs only with aerosol generating procedures. Recommendations determining infection control measures to ensure healthcare worker safety follow these…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:11

M
AA pubmed: head and neckRedistributing of Working Schedules by the Infective Principle – Will The COVID-19 Pandemic Finally Make Us Remember the Names of People We Shake Hands With?Related ArticlesRedistributing of Working Schedules by the Infective Principle – Will The COVID-19 Pandemic Finally Make Us Remember the Names of People We Shake Hands With? Infect Control Hosp Epidemiol. 2020 Apr 21;:1-5 Authors: Marko Ć, Košec A, Petrana B PMID: 32312359 [PubMed – as supplied by publisher]AA pubmed:…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:10

Indigenous Management of Parotid Sialocele Using Foley’s Catheter: A Report of Two Cases
Indigenous Management of Parotid Sialocele Using Foley’s Catheter: A Report of Two Cases: AbstractBackgroundParotid gland and duct injuries are rare complications following surgery of parotid gland and temporomandibular joint. Sialocele is a cavity filled with saliva, usually formed as a result of trauma to salivary gland/duct or an iatrogenic complication of surgery. Several methods of managing parotid duct injury have been reported in the literature. In this article, we describe an indigenous way…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:07

Synovial Chondromatosis of the Temporomandibular Joint
Synovial Chondromatosis of the Temporomandibular Joint: AbstractSynovial chondromatosis is a rare condition characterized by the presence of loose cartilaginous bodies, due to the abnormal proliferation of synovial membrane. However, its manifestation in the temporomandibular joint is a rare finding, occurring predominantly in females. This case report describes the clinical features, diagnosis and management of a case of synovial chondromatosis.

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:07

Prediction mode of more than 5 central lymph nodes metastases in clinically node-negative ipsilateral papillary thyroid carcinoma with tumor size 1 to 4 cm.
Prediction mode of more than 5 central lymph nodes metastases in clinically node-negative ipsilateral papillary thyroid carcinoma with tumor size 1 to 4 cm.: Related ArticlesPrediction mode of more than 5 central lymph nodes metastases in clinically node-negative ipsilateral papillary thyroid carcinoma with tumor size 1 to 4 cm.Medicine (Baltimore). 2020 Apr;99(16):e19809Authors: Jin L, Sun HL, Zhou L, Xie L, Zhuang YY, Wang JBAbstract According to the 2015 American Thyroid Association guidelines,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:06

Case report of a cystic parathyroidal adenoma with rapid growth induced by cinacalcet.
Case report of a cystic parathyroidal adenoma with rapid growth induced by cinacalcet.: Related ArticlesCase report of a cystic parathyroidal adenoma with rapid growth induced by cinacalcet.BMC Endocr Disord. 2020 Apr 20;20(1):53Authors: Werner C, Lupp A, Mtuka-Pardon G, Kloos C, Wolf G, Aschenbach R, Biermann A, Freesmeyer M, Seifert PAbstract BACKGROUND: Primary hyperparathyroidism is a rare condition of disease which can seldomly present as giant retrotrhyroideal cysts, complicating the…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:05

M
AA pubmed: head and neckEffect of Noise Exposure on 1,382 Metallurgical Workers in Periodic Audiometric Evaluation: A Cohort Study.Related ArticlesEffect of Noise Exposure on 1,382 Metallurgical Workers in Periodic Audiometric Evaluation: A Cohort Study. Audiol Neurootol. 2020 Apr 21;:1-6 Authors: Silva VAR, Guimarães AC, Lavinsky J, Pauna HF, Castilho AM, Crespo AN Abstract INTRODUCTION: Noise-induced hearing loss is the most preventable cause of auditory impairment. Periodic audiometric evaluations…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:05

CD44v3 protein-carrying tumor-derived exosomes in HNSCC patients’ plasma as potential noninvasive biomarkers of disease activity.
CD44v3 protein-carrying tumor-derived exosomes in HNSCC patients’ plasma as potential noninvasive biomarkers of disease activity.: Related ArticlesCD44v3 protein-carrying tumor-derived exosomes in HNSCC patients’ plasma as potential noninvasive biomarkers of disease activity.Oncoimmunology. 2020;9(1):1747732Authors: Theodoraki MN, Matsumoto A, Beccard I, Hoffmann TK, Whiteside TLAbstract The molecular cargo of tumor-cell-derived exosomes (TEX) mimics that of parental tumor cells. Thus, TEX…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:03

Squamous Cell and Adenoid Cystic Carcinoma Collision Tumor of the Soft Palate Treated with Surface Mold Brachytherapy.
Squamous Cell and Adenoid Cystic Carcinoma Collision Tumor of the Soft Palate Treated with Surface Mold Brachytherapy.: Surface mold brachytherapy (SMB) is a well-established treatment for early stage head and neck cancers involving accessible sites. It has evolved from the radium era to low-dose rate and now to high-dose rate intensity-modulated interventional brachytherapy.Sep 9, 2019High-dose rate surface mold brachytherapy in a case of …Related ArticlesSquamous Cell and Adenoid Cystic Carcinoma…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:03

Remove ads

Cat-scratch Disease with Parinaud’s Oculoglandular Syndrome.
Cat-scratch Disease with Parinaud’s Oculoglandular Syndrome.: Parinaud’s oculoglandular syndrome is the combination of granulomatous conjunctivitis in one eye, and swollen lymph nodes in front of the ear on the same side. Most cases are caused by cat-scratch disease, although it is an unusual feature of this condition. Occasionally it may be caused by other infections.Parinaud’s oculoglandular syndrome – WikipediaRelated ArticlesCat-scratch Disease with Parinaud’s Oculoglandular Syndrome.Turk Arch…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:02

Necrotizing Fasciitis due to Candida Infection after Thyroid Surgery.
Necrotizing Fasciitis due to Candida Infection after Thyroid Surgery.: Related ArticlesNecrotizing Fasciitis due to Candida Infection after Thyroid Surgery.Turk Arch Otorhinolaryngol. 2020 Mar;58(1):56-60Authors: Aslıer MAbstract Surgical site infections (SSIs) after thyroidectomy are very rare as it is a clean case surgery, even the patterns for the use of prophylactic antibiotics is disputable. Cutaneous and subcutaneous tissue infections are the most common type of SSIs that develop due…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:01

Ewing Sarcoma of Larynx: A Rare Case in a 5-Year-Old Boy.
Ewing Sarcoma of Larynx: A Rare Case in a 5-Year-Old Boy.: Related ArticlesEwing Sarcoma of Larynx: A Rare Case in a 5-Year-Old Boy.Turk Arch Otorhinolaryngol. 2020 Mar;58(1):65-68Authors: Pasha HA, Ghaloo SK, Wasif M, Siddiqui MI, Din NUAbstract Ewing Sarcoma of the head and neck region is an extremely rare entity. Treatment usually involves surgery, chemotherapy and radiotherapy in varying sequences. We present the third case to date of Ewing sarcoma of the larynx in a paediatric population….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:00

Eccrine porocarcinoma of the head and neck: Meta-analysis of 120 cases.
Eccrine porocarcinoma of the head and neck: Meta-analysis of 120 cases.: Eccrine porocarcinomas, are very rare malignant adnexal tumors arising from intra-epidermal ductal portion of eccrine sweat gland. More than 50% cases involve lower extremities (3). On rare occasion, it may involve head and neck region, upper limbs, trunk and abdomen (1, 3).Eccrine Porocarcinoma of Scalp: a Rare Case Report – NCBIRelated ArticlesEccrine porocarcinoma of the head and neck: Meta-analysis of 120 cases.Head Neck….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:59

Incidence and survival trends of parotid malignancies over 42 years.
Incidence and survival trends of parotid malignancies over 42 years.: Related ArticlesIncidence and survival trends of parotid malignancies over 42 years.Head Neck. 2020 Apr 21;:Authors: Gupta A, Koochakzadeh S, Neskey DM, Nguyen SA, Lentsch EJAbstract BACKGROUND: There is a paucity of information regarding the incidence and survival of parotid malignancies over time. METHODS: The Surveillance, Epidemiology, and End Results population-based cancer registry was queried for parotid malignancies…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:58

M
Latest headlines from BMJSeven days in medicine: 15-21 April 2020Covid-19Care home residents and staff are promised testsThe pledge to boost covid-19 testing for staff in UK care homes must be delivered promptly and be matched with greater transparency about the…Latest headlines from BMJnowMark above section as read pubmed: philosophy for medic…Comparing Quality of Life in Breast Cancer Patients Who Underwent Mastectomy Versus Breast-Conserving Surgery: A Meta-Analysis.Related ArticlesComparing…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:57

Usefulness of intraoperative determination of central lymph node metastasis by palpation in papillary thyroid cancer.
Usefulness of intraoperative determination of central lymph node metastasis by palpation in papillary thyroid cancer.: Related ArticlesUsefulness of intraoperative determination of central lymph node metastasis by palpation in papillary thyroid cancer.Yeungnam Univ J Med. 2020 Apr 22;:Authors: Kim WW, Lee J, Jung JH, Park HY, Kim WH, Kim HJ, Park JY, Tufano RPAbstract Background: This study evaluated the usefulness of judgment of central lymph node (LN) metastasis by surgeon’s palpation in…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:56

M
pubmed: sleepEAN/ERS/ESO/ESRS statement on the impact of sleep disorders on risk and outcome of stroke.Related ArticlesEAN/ERS/ESO/ESRS statement on the impact of sleep disorders on risk and outcome of stroke. Eur J Neurol. 2020 Apr 20;: Authors: Bassetti CLA, Randerath W, Vignatelli L, Ferini-Strambi L, Brill AK, Bonsignore MR, Grote L, Jennum P, Leys D, Minnerup J, Nobili L, Tonia T, Morgan R, Kerry J, Riha R, McNicholas WT, Papavasileiou V Abstract BACKGROUND: Sleep disorders are highly prevalent…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:54

M
Latest Results for Education and Information TechnologiesParents’ beliefs about and associations to their elementary children’s home technology usageAbstract This study sought to gather information through a survey of how newcomer parents’ beliefs about technology usage and how they engage with technology as they support their children with twenty-first century literacies. Parent respondents (N = 70) were drawn from two publicly funded schools in the Niagara Region, Ontario, Canada, where the population…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:54

The 24-inch gauge and the common gavel: an entered apprentice mason’s perspective on the medical profession……………..Freemason physicians such as Alexander Fleming, Charles Mayo, William Withering, and Edward Jenner have left a medical legacy
The 24-inch gauge and the common gavel: an entered apprentice mason’s perspective on the medical profession.: Related ArticlesThe 24-inch gauge and the common gavel: an entered apprentice mason’s perspective on the medical profession.Proc (Bayl Univ Med Cent). 2020 Apr;33(2):298-301Authors: Kopel JAbstract By developing their character and philosophy, Freemasons have sought to improve their communities and society through the arts, sciences, humanities, and other fields and have made important…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:53

Pediatric Patients with Previous Anaphylactic Reactions to General Anesthesia: a Review of Literature, Case Report, and Anesthetic Considerations……………..Full use of inhalation anesthesia without unnecessary neuromuscular blockade agents and avoidance of latex is recommended when the surgery is urgent or skin tests for children cannot be performed in time.
Pediatric Patients with Previous Anaphylactic Reactions to General Anesthesia: a Review of Literature, Case Report, and Anesthetic Considerations: AbstractPurpose of ReviewIt is rare to see pediatric patients with previous perioperative anaphylaxis receiving future anesthesia, but it is critical to understand how to choose assessments, interpret the results, and develop a future anesthetic plan.Recent FindingsAnalysis of the results revealed that patients, at any age, regardless of sex and nationality,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:49

Targeting tumor-associated macrophages in head and neck squamous cell carcinoma.
Targeting tumor-associated macrophages in head and neck squamous cell carcinoma.: Related ArticlesTargeting tumor-associated macrophages in head and neck squamous cell carcinoma.Oral Oncol. 2020 Apr 18;106:104723Authors: Li B, Ren M, Zhou X, Han Q, Cheng LAbstract In head and neck squamous cell carcinoma (HNSCC), tumor-associated macrophages (TAMs) are associated with a poorer prognosis. TAMs, derived from inflammatory monocyte, play a critical role in regulating tumor progression. Generally,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:49

Vitamin D Status as a Predictor of Postoperative Hypocalcemia after Thyroidectomy.
Vitamin D Status as a Predictor of Postoperative Hypocalcemia after Thyroidectomy.: Related ArticlesVitamin D Status as a Predictor of Postoperative Hypocalcemia after Thyroidectomy.Otolaryngol Head Neck Surg. 2020 Apr 21;:194599820917907Authors: Rubin SJ, Park JH, Pearce EN, Holick MF, McAneny D, Noordzij JPAbstract OBJECTIVE: To determine whether perioperative vitamin D levels are predictive of postoperative hypocalcemia in patients receiving thyroidectomy. STUDY DESIGN: Single center…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:48

Anesthesia for TORS for Oropharyngeal Carcinoma: Factors Associated with Prolonged Phase I Postanesthesia Recovery.
Anesthesia for TORS for Oropharyngeal Carcinoma: Factors Associated with Prolonged Phase I Postanesthesia Recovery.: Related ArticlesAnesthesia for TORS for Oropharyngeal Carcinoma: Factors Associated with Prolonged Phase I Postanesthesia Recovery.Otolaryngol Head Neck Surg. 2020 Apr 21;:194599820915529Authors: Puccinelli CL, Moore EJ, Yin LX, Price DL, Janus JR, Weingarten TN, Van Abel KMAbstract OBJECTIVES: Clinical variables affecting anesthetic recovery following transoral robotic surgery…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:48

M
BMJ Open Current IssueEffect of time interval from diagnosis to treatment for non-small cell lung cancer on survival: a national cohort study in TaiwanObjectivesThis study aimed to determine if treatment delay after non-small cell lung cancer (NSCLC) diagnosis impacts patient survival rate. Study designThis study is a natural experiment in Taiwan. A retrospective cohort investigation was conducted from 2004 to 2010, which included 42 962 patients with newly diagnosed NSCLC. MethodsWe identified…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:47

Event-Related Potential Evidence of Enhanced Visual Processing in Auditory-Associated Cortex in Adults with Hearing Loss
Event-Related Potential Evidence of Enhanced Visual Processing in Auditory-Associated Cortex in Adults with Hearing Loss: Objective: The present study investigated the characteristics of visual processing in the auditory-associated cortex in adults with hearing loss using event-related potentials. Methods: Ten subjects with bilateral postlingual hearing loss were recruited. Ten age- and sex-matched normal-hearing subjects were included as controls. Visual (“sound” and “non-sound” photos)-evoked potentials…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:46

M
Latest Results for European Journal on Criminal Policy and ResearchHousing Ex-Offenders in the Netherlands: Balancing Neighbourhood Safety and Human RightsAbstract The Universal Declaration of Human Rights recognises stable housing as a prerequisite for an adequate standard of living. A home provides shelter and enables personal development, thus contributing to the individual’s well-being. Despite this, however, many struggle to find a place to live. In the Netherlands, people with a history of…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:45

Evidence of Failure of Oral Third-Generation Cephalosporin Treatment for Shigella sonnei Infection
Evidence of Failure of Oral Third-Generation Cephalosporin Treatment for Shigella sonnei Infection: AbstractIn 2017, state health departments notified the Centers for Disease Control and Prevention about 4 patients with shigellosis who experienced persistent illness after treatment with oral third-generation cephalosporins. Given increasing antibiotic resistance among Shigella, these cases highlight the need to evaluate the efficacy of oral cephalosporins for shigellosis.The disease is caused by Shigella bacteria,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:41

Moderate to severe hyperphosphataemia as an independent prognostic factor for 28-day mortality in adult patients with sepsis
Moderate to severe hyperphosphataemia as an independent prognostic factor for 28-day mortality in adult patients with sepsis: BackgroundIschaemic tissue injury caused by tissue hypoperfusion is one of the major consequences of sepsis. Phosphate concentrations are elevated in ischaemic tissue injury. This study was performed to investigate the association of phosphate concentrations with mortality in patients with sepsis.MethodsThis was a retrospective cohort study of patients with sepsis conducted…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:40

Morphological study of the rabbit gustatory lingual papillae during postnatal life by light and scanning electron microscopy
Morphological study of the rabbit gustatory lingual papillae during postnatal life by light and scanning electron microscopy: AbstractThis study aimed to investigate the postnatal morphological features of rabbit’s lingual gustatory papillae using histological, histochemical, morphometrical and scanning electron microscopical studies. A total of 48 New Zealand rabbits (1, 7, 15, 23, 30, 60 days postnatal) were used as the material. Tongue consisted of an apex, body and root with three types of gustatory…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:40

Remove ads

Advances and perspectives of dendritic cell-based active immunotherapies in follicular lymphoma
Advances and perspectives of dendritic cell-based active immunotherapies in follicular lymphoma: AbstractFollicular lymphoma (FL) is a remarkably immune-responsive malignancy, which is still considered incurable. As, standard immunochemotherapy is complex, toxic and not curative, improvement in FL care is now a crucial topic in hemato-oncology. Recently, we and others have shown that dendritic cell (DC)-based therapies allow a specific immune response associated with sustained lymphoma regression…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:39

Massive pulmonary embolism in pregnancy: intra-arrest thrombolysis and resuscitative hysterotomy
Massive pulmonary embolism in pregnancy: intra-arrest thrombolysis and resuscitative hysterotomy: Massive pulmonary embolism (PE) is a leading cause of maternal death and may require intra-arrest thrombolysis as well as resuscitative hysterotomy. The case presented is a primigravida in her mid-30s at 28 weeks gestation. The patient presented to the emergency department after out-of-hospital cardiac arrest. Return of spontaneous circulation (ROSC) was achieved but not sustained. Episodic cardiopulmonary…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:38

Supraclavicular left neck mass: an unusual presentation of metastatic testicular cancer in two older men
Supraclavicular left neck mass: an unusual presentation of metastatic testicular cancer in two older men: Two male patients, aged 55 and 75 years, were referred to the ENT and haematology team respectively, with an asymptomatic left supraclavicular neck mass. Investigations revealed metastatic primary testicular seminoma. CT contrast study of the thorax, abdomen and pelvis demonstrated an additional left para-aortic nodal mass in both cases. The initial presentation of a solitary left neck lump from…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:37

Malignant peripheral nerve sheath tumour of thyroid: a diagnostic dilemma
Malignant peripheral nerve sheath tumour of thyroid: a diagnostic dilemma: Malignant peripheral nerve sheath tumours of thyroid are rare entities that can present a diagnostic dilemma. We present the case of a patient who presented with neck mass with a history of multiple neck surgeries and airway compression. The patient’s previous histopathology was mistaken for Riedel’s thyroiditis in an outside hospital, which delayed appropriate treatment leading to suffering on part of the patient and frustration…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:36

M
BMJ Case Reports Last 6 IssuesFollicular dendritic cell sarcoma and its response to immune checkpoint inhibitors nivolumab and ipilimumabFollicular dendritic cell sarcoma (FDCS) is a rare and unusual cancer that arises from sustentacular cells of the lymph node that present antigen to B cells, rather than lymphocytes themselves. While surgery for primary disease is still paramount in primary management, for unresectable, recurrent and metastatic tumours, FDCS is frequently treated with anthracycline-based…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:36

Bilateral Fan-Shaped Septal Extension Struts in Augmentation Rhinoplasty
Bilateral Fan-Shaped Septal Extension Struts in East Asian Augmentation Rhinoplasty: AbstractBackgroundFor costal cartilage-based rhinoplasty, a method that could properly manage warping of the columellar strut graft and facilitate establishing a stable cartilaginous framework remains desirable. In this study, the authors present a new graft design named bilateral septal extension strut. It utilizes a pair of cartilage grafts with the shape of a fan, which are bilaterally fixated to the septum. Such…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:34

M
Latest Results for AGEMitochondrial adaptations in liver and skeletal muscle to pro-longevity nutritional and genetic interventions: the crosstalk between calorie restriction and CYB5R3 overexpression in transgenic miceAbstract Calorie restriction without malnutrition (CR) is considered as the most effective nongenetic nor pharmacological intervention that promotes healthy aging phenotypes and can extend lifespan in most model organisms. Lifelong CR leads to an increase of cytochrome b5 reductase-3…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:34

M
RSC – Photochem. Photobiol. Sci. latest articlesEffect of ultraviolet radiation on vertebrate animals: update from ethological and medical perspectivesPhotochem. Photobiol. Sci., 2020, Advance ArticleDOI: 10.1039/C9PP00488B, PerspectiveClaire Vergneau-Grosset, Franck PéronMany animals under human care are kept indoors to prevent infectious diseases, to facilitate environment control, or due to the lifestyle of their owners. This article will review published information about ultraviolet effects…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:33

Correlation of p53 expression with Clinical Presentation and Prognosis of Oral Squamous Cell Carcinoma Patients: A Pilot Study
Correlation of p53 expression with Clinical Presentation and Prognosis of Oral Squamous Cell Carcinoma Patients: A Pilot Study: AbstractMutations of p53 gene is one of the most common events in human cancers including oral squamous cell carcinoma (OSCC). However, its role in carcinogenesis and association with regard to prognosis is still under investigation and unclear. The aim was to study the expression of p53 in patients of OSCC and correlation with clinical presentation and prognosis. In this…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:32

The current modified technique of uvulopalatopharyngoplasty/expansion sphincteroplasty aims to maximize relocation and tension on the palatopharyngeus muscle, opening the retropalatal airway and the palatal genu, and minimizing tension on the final mucosal closure……………….Palatopharyngoplasty and Palatal Anatomy and Phenotypes for Treatment of Sleep Apnea in the Twenty-first Century
Palatopharyngoplasty and Palatal Anatomy and Phenotypes for Treatment of Sleep Apnea in the Twenty-first Century: Successful palatopharyngoplasty is critical for successful sleep apnea surgery. Traditional uvulopalatopharyngoplasty was primarily excisional, whereas newer techniques, such as expansion sphincterpharyngoplasty, are more reconstructive. Studies of flow dynamics even demonstrate that the effectiveness of maxillofacial surgery is significantly mediated through stiffening and enlargement…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:32

Implantable Neurostimulation for Treatment of Sleep Apnea
Implantable Neurostimulation for Treatment of Sleep Apnea: Hypoglossal nerve stimulation (HNS) therapy represents a novel approach and a paradigm shift in the evolution of obstructive sleep apnea (OSA) treatment as a hybrid surgically implanted, medically titratable device. Unlike traditional sleep apnea surgical procedures, HNS augments the neuromuscular activity of the pharynx, preserves upper airway structure and function, and has the potential to provide multilevel upper airway improvement with…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:31

M
Journal of Dairy ScienceEstimating degradation of individual essential amino acids in fish meal and blood meal by rumen microbes in a dual-flow continuous-culture systemPublication date: Available online 22 April 2020Source: Journal of Dairy ScienceAuthor(s): S. Gargallo, A. Ferret, S. CalsamigliaJournal of Dairy Science6h<em>Symposium review:</em> Development, implementation, and perspectives of health evaluations in the United States<a name="bfn1" href="#fn1" aria-label="open footnote"…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:30

Sonographic exploration for fascial exploration (SEFE) in necrotizing fasciitis: a case report
Sonographic exploration for fascial exploration (SEFE) in necrotizing fasciitis: a case report: AbstractBackgroundNecrotizing skin and soft tissue infections are life-threatening conditions. Reliance on gas in tissue planes leads to worsened outcomes in patients with non-gas forming types of necrotizing fasciitis (NF).Case presentationWe present a case of Group A Strep (GAS) necrotizing fasciitis, which was identified at bedside with point-of-care ultrasound (US) including an area of subfascial fluid….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:28

M
edoc: No conditions. Results ordered -Date Deposited.Connecting single conductive polymers to a single functional moleculeWe have developed a method using a scanning tunneling microscope (STM) probe tip to control the chain polymerization of diacetylene compounds in a self-ordered layer, thereby creating conjugated polydiacetylene nanowires. When a small amount of phthalocyanine was deposited on a molecular layer of diacetylene compound, we found adsorbed and stabilized phthalocyanine single molecules….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:27

M
edoc: No conditions. Results ordered -Date Deposited.Standardized protocols and procedures can precisely and accurately quantify non-structural carbohydratesNon-structural carbohydrates (NSCs), the stored products of photosynthesis, building blocks for growth and fuel for respiration, are central to plant metabolism, but their measurement is challenging. Differences in methods and procedures among laboratories can cause results to vary widely, limiting our ability to integrate and generalize patterns…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:26

M
Latest headlines from BMJHelen Salisbury: Who is vulnerable?The Easter bank holidays were cancelled for general practices at short notice, to take the pressure off out-of-hours services in anticipation of a rise in demand. Most of my patients assumed that we…Latest headlines from BMJ18hMatt Morgan: Hold onto your red threadMy Welsh comprehensive school education stood me in good stead for rugby, but less so for Greek mythology. I may have come late to the classics, but I have recently read about…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:24

An impact of microscopic positive margin on incomplete response after I-131 treatment in differentiated thyroid cancer
An impact of microscopic positive margin on incomplete response after I-131 treatment in differentiated thyroid cancer: AbstractObjectiveTo find an impact of microscopic positive margin on incomplete response after initial I-131 therapy in differentiated thyroid cancer.MethodsWe retrospectively recruited patients with differentiated thyroid cancer who underwent total thyroidectomy and received the first dose of radioiodine during January 2014–February 2018. Patients with grossly incomplete tumor…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:24

M
Hindawi Publishing CorporationEnergy Dissipation Characteristic of Red Sandstone in the Dynamic Brazilian Disc Test with SHPB SetupIn order to quantitatively investigate the energy dissipation characteristic during the dynamic tension failure of rock materials, the dynamic Brazilian disc tests on red sandstone were conducted using the split Hopkinson pressure bar (SHPB) setup. The states of the specimens after different incident energies can be divided into three forms (i.e., the unruptured state,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:23

M
Remove ads Hindawi Publishing CorporationEffect of Huangqin Tang on Urine Metabolic Profile in Rats with Ulcerative Colitis Based on UPLC-Q-Exactive Orbitrap MSAs a classic prescription, Huangqin Tang (HQT) has been widely applied to treat ulcerative colitis (UC), although its pharmacological mechanisms are not clear. In this study, urine metabolomics was first analysed to explore the therapeutic mechanisms of HQT in UC rats induced by TNBS. We identified 28 potential biomarkers affected by HQT that…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:22

The Postoperative Lymphocyte to Monocyte Ratio Change Predicts Poor Clinical Outcome in Patients with Esophageal Squamous Cell Carcinoma Undergoing Curative Resection
The Postoperative Lymphocyte to Monocyte Ratio Change Predicts Poor Clinical Outcome in Patients with Esophageal Squamous Cell Carcinoma Undergoing Curative Resection: Background. Postoperative lymphocyte to monocyte ratio (post-LMR) change (LMRc) reflects the dynamic change of balance between inflammatory reaction and immune reaction after curative operation. An elevated preoperative LMR (pre-LMR) has been shown to be a prognostic factor in patients with esophageal squamous cell carcinoma (ESCC),…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:21

Remove ads

M
JBC Papers in Press{alpha}2, 3-linkage of sialic acid to a GPI-anchor and an unpredicted GPI attachment site in human prion protein [Glycobiology and Extracellular Matrices]Prion diseases are transmissible, lethal neurodegenerative disorders caused by accumulation of the aggregated scrapie form of prion protein (PrPSc) after conversion of cellular prion protein (PrPC). The glycosylphosphatidylinositol (GPI) anchor of PrPC is involved in prion disease pathogenesis, and especially sialic acid in a…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:20

Giant Thrombosis at Left Anterior Descending Artery Aneurysm in a 10-Year Old Boy with Granulomatosis with Polyangiitis
Giant Thrombosis at Left Anterior Descending Artery Aneurysm in a 10-Year Old Boy with Granulomatosis with Polyangiitis: Granulomatosis with polyangiitis (GPA), necrotizing vasculitis of small and medium-sized vessels, is traditionally believed to mainly affect respiratory tract with additional focal kidney involvements as its primary manifestations with a relatively rare annual incidence rate of 20-50 cases per million. Six percent of the affected cases have cardiac involvements; among which, aneurysms…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:20

M
MCP Papers in PressRobust summarization and inference in proteome-wide label-free quantification [Research]Label-Free Quantitative mass spectrometry based workflows for differential expression (DE) analysis of proteins impose important challenges on the data analysis due to peptide-specific effects and context dependent missingness of peptide intensities. Peptide-based workflows, like MSqRob, test for DE directly from peptide intensities and outperform summarization methods which first aggregate…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:19

Medicine by Alexandros G. Sfakianakis,
RCNull Cell Adenoma of the Pituitary: Pseudo-rosettes Say It Best When Immunohistochemistry Says Nothing At All!Related ArticlesNull Cell Adenoma of the Pituitary: Pseudo-rosettes Say It Best When Immunohistochemistry Says Nothing At All! Head Neck Pathol. 2019 Dec;13(4):677-680 Authors: Singh V, Gupta K, Salunke P, Dhandapani SS Abstract Null cell adenoma is composed of adenohypophyseal cells that show no evidence of any specific cell type differentiation by immunohistochemistry or transcription…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

Wed Apr 22, 2020 10:05

Mark above section as read

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

M
VirusesViruses, Vol. 12, Pages 474: Determination of Protein Interactions among Replication Components of Apple Necrotic Mosaic VirusViruses, Vol. 12, Pages 474: Determination of Protein Interactions among Replication Components of Apple Necrotic Mosaic Virus Viruses doi: 10.3390/v12040474 Authors: Zhen-Lu Zhang Fu-Jun Zhang Peng-Fei Zheng Yin-Huan Xie Chun-Xiang You Yu-Jin Hao Apple mosaic disease is one of the most widely distributed and destructive diseases in apple cultivation worldwide, especially…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:13

M
NutrientsNutrients, Vol. 12, Pages 1171: Normal-Weight Obesity Is Associated with Poorer Cardiometabolic Profile and Lower Physical Fitness Levels in Children and AdolescentsNutrients, Vol. 12, Pages 1171: Normal-Weight Obesity Is Associated with Poorer Cardiometabolic Profile and Lower Physical Fitness Levels in Children and Adolescents Nutrients doi: 10.3390/nu12041171 Authors: Antonio García-Hermoso Cesar Agostinis-Sobrinho Gloria Eugenia Camargo-Villalba Nubia Mercedes González-Jiménez Mikel…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:12

M
MedicinaMedicina, Vol. 56, Pages 192: The Role of VEGFA, COX2, HUR and CUGBP2 in Predicting the Response to Neoadjuvant Therapy in Rectal Cancer PatientsMedicina, Vol. 56, Pages 192: The Role of VEGFA, COX2, HUR and CUGBP2 in Predicting the Response to Neoadjuvant Therapy in Rectal Cancer Patients Medicina doi: 10.3390/medicina56040192 Authors: Pauzas Gyvyte Latkauskas Kairevice Lizdenis Svagzdys Birgiolaite Kuliaviene Kupcinskas Tamelis Background and objectives: The effectiveness of neoadjuvant…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:11

M
International Journal of Molecular SciencesIJMS, Vol. 21, Pages 2936: Sensitivity of the Fasciae to the Endocannabinoid System: Production of Hyaluronan-Rich Vesicles and Potential Peripheral Effects of Cannabinoids in Fascial TissueIJMS, Vol. 21, Pages 2936: Sensitivity of the Fasciae to the Endocannabinoid System: Production of Hyaluronan-Rich Vesicles and Potential Peripheral Effects of Cannabinoids in Fascial Tissue International Journal of Molecular Sciences doi: 10.3390/ijms21082936 Authors:…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:10

M
International Journal of Environmental Research and Public HealthIJERPH, Vol. 17, Pages 2894: Evidence Supports PA Prescription for Parkinson’s Disease: Motor Symptoms and Non-Motor Features: A Scoping ReviewIJERPH, Vol. 17, Pages 2894: Evidence Supports PA Prescription for Parkinson’s Disease: Motor Symptoms and Non-Motor Features: A Scoping Review International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082894 Authors: Yi-Chen Cheng Chun-Hsien Su Parkinson’s disease…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:10

M
CellsCells, Vol. 9, Pages 1048: VEGF Treatment Ameliorates Depression-Like Behavior in Adult Offspring After Maternal Immune ActivationCells, Vol. 9, Pages 1048: VEGF Treatment Ameliorates Depression-Like Behavior in Adult Offspring After Maternal Immune Activation Cells doi: 10.3390/cells9041048 Authors: Spyridon Sideromenos Claudia Lindtner Alice Zambon Orsolya Horvath Angelika Berger Daniela D. Pollak Maternal immune activation (MIA) during pregnancy impacts offspring neurodevelopmental trajectories…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:09

M
AntibioticsAntibiotics, Vol. 9, Pages 200: Investigating Bacteriophages Targeting the Opportunistic Pathogen Acinetobacter baumanniiAntibiotics, Vol. 9, Pages 200: Investigating Bacteriophages Targeting the Opportunistic Pathogen Acinetobacter baumannii Antibiotics doi: 10.3390/antibiotics9040200 Authors: Kathryn M. Styles Rapee Thummeepak Udomluk Leungtongkam Sophie E. Smith Gabrielle S. Christie Andrew Millard John Moat Christopher G. Dowson Elizabeth M. H. Wellington Sutthirat Sitthisak Antonia…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:09

#
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia,

Telephone consultation 11855 int 1193,

Medicine by Alexandros G. Sfakianakis,

RC
Null Cell Adenoma of the Pituitary: Pseudo-rosettes Say It Best When Immunohistochemistry Says Nothing At All!Related ArticlesNull Cell Adenoma of the Pituitary: Pseudo-rosettes Say It Best When Immunohistochemistry Says Nothing At All! Head Neck Pathol. 2019 Dec;13(4):677-680 Authors: Singh V, Gupta K, Salunke P, Dhandapani SS Abstract Null cell adenoma is composed of adenohypophyseal cells that show no evidence of any specific cell type differentiation by immunohistochemistry or transcription factors…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:58

RC
Leukocyte-mimicking nanovesicles for effective doxorubicin delivery to treat breast cancer and melanoma.Related ArticlesLeukocyte-mimicking nanovesicles for effective doxorubicin delivery to treat breast cancer and melanoma. Biomater Sci. 2020 Jan 01;8(1):333-341 Authors: Molinaro R, Martinez JO, Zinger A, De Vita A, Storci G, Arrighetti N, De Rosa E, Hartman KA, Basu N, Taghipour N, Corbo C, Tasciotti E Abstract In the last decades, several approaches were developed to design drug delivery systems…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:57

RC
A case of ruptured splenic cyst with elevated serum levels of CEA treated by laparoscopic unroofing.Related ArticlesA case of ruptured splenic cyst with elevated serum levels of CEA treated by laparoscopic unroofing. Clin J Gastroenterol. 2019 Dec;12(6):642-649 Authors: Okuno M, Yuasa N, Takeuchi E, Goto Y, Miyake H, Nagai H, Yoshioka Y, Miyata K Abstract Splenic cysts are rare and tend to have elevated tumor markers, of which carbohydrate antigen (CA) 19-9 is the most frequently elevated. Therefore,…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:56

RC
Minimally invasive lateral approaches for the treatment of spinal tumors: single-position surgery without the "flip".Related ArticlesMinimally invasive lateral approaches for the treatment of spinal tumors: single-position surgery without the "flip". J Spine Surg. 2020 Mar;6(1):62-71 Authors: Laratta JL, Weegens R, Malone KT, Chou D, Smith WD Abstract Although primary tumors of the spine and neural elements are rare, metastatic disease to the spine is quite common. Traditionally, surgical treatment…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:55

The Benefits of Adjuvant Trastuzumab for HER-2-Positive Salivary Gland Cancers.
The Benefits of Adjuvant Trastuzumab for HER-2-Positive Salivary Gland Cancers.: Related ArticlesThe Benefits of Adjuvant Trastuzumab for HER-2-Positive Salivary Gland Cancers.Oncologist. 2020 Apr 20;:Authors: Hanna GJ, Bae JE, Lorch JH, Haddad RI, Jo VY, Schoenfeld JD, Margalit DN, Tishler RB, Goguen LA, Annino DJ, Chau NGAbstract BACKGROUND: Although high-grade salivary gland cancers (SGCs) often express androgen receptor (AR) and/or HER-2/neu, therapeutically targeting these receptors…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:49

Characteristics of Atypical Orbital Complications of Sinusitis. : Five patients were identified with atypical complications in the orbital area. Two of the 5 patients exhibited vision loss without any other symptoms. Two patients showed diplopia with or without ptosis. One patient had a headache and ptosis. Complete recovery was noted in 4 of the 5 patients after endoscopic sinus surgery.
Characteristics of Atypical Orbital Complications of Sinusitis.: Related ArticlesCharacteristics of Atypical Orbital Complications of Sinusitis.J Craniofac Surg. 2020 Apr 16;:Authors: Kim BY, Lee S, Jeon J, Lim IG, Choi GCAbstract INTRODUCTION: Orbital complications of rhinosinusitis in adults are scarcely discussed in the literature. We defined atypical orbital complications as those without typical orbital invasion and not classified by the Chandler classification. These complications…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:49

Modified Endoscopic Dacryocystorhinostomy Using the Middle Uncinate Process Approach.
Modified Endoscopic Dacryocystorhinostomy Using the Middle Uncinate Process Approach.: Related ArticlesModified Endoscopic Dacryocystorhinostomy Using the Middle Uncinate Process Approach.J Craniofac Surg. 2020 Apr 16;:Authors: Yang J, Cao Z, Gu ZAbstract PURPOSE: Endoscopic dacryocystorhinostomy (EDCR) is advantageous in that it avoids facial scar formation, does not damage the medial canthus ligament, and recovers quickly. The main purpose of EDCR is to establish a fistula large enough…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:48

M
Case Reports in MedicineGastrointestinal Cryptococcosis Associated with Intestinal LymphangiectasiaIntestinal lymphangiectasia is a pathological dilation of enteric lymphatic vessels resulting in lymph leakage to the intestinal lumen. This chronic lymph leakage leads to a state of immunosuppression secondary to the loss of humoral and cellular components of the immune system and represents a potential risk factor for opportunistic infections. We report a case of protein-losing enteropathy in a seemingly…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:46

M
SAGE Publications Inc: Technology in Cancer Research & Treatment: Table of ContentsAtlas Sampling for Prone Breast Automatic Segmentation of Organs at Risk: The Importance of Patients’ Body Mass Index and Breast Cup Size for an Optimized Contouring of the Heart and the Coronary VesselsTechnology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Objective:Delineation of organs at risk is a time-consuming task. This study evaluates the benefits of using single-subject…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:44

M
pubmed: sleepSerum levels of C1q/TNF-related protein-3 in inflammatory bowel disease patients and its inverse association with inflammatory cytokines and insulin resistance.Related ArticlesSerum levels of C1q/TNF-related protein-3 in inflammatory bowel disease patients and its inverse association with inflammatory cytokines and insulin resistance. IUBMB Life. 2020 Apr 20;: Authors: Mohamadinarab M, Ahmadi R, Gholamrezayi A, Rahvar F, Naghdalipour M, Setayesh L, Moradi N, Fadaei R, Chamani E, Tavakoli…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:31

M
pubmed: philosophy for medic…Validity of the EQ-5D in patients with pemphigus vulgaris and pemphigus foliaceus.Related ArticlesValidity of the EQ-5D in patients with pemphigus vulgaris and pemphigus foliaceus. Br J Dermatol. 2019 04;180(4):802-809 Authors: Tamási B, Brodszky V, Péntek M, Gulácsi L, Hajdu K, Sárdy M, Szegedi A, Bata-Csörgő Z, Kinyó Á, Rencz F Abstract BACKGROUND: No studies to date have employed the EuroQoL EQ-5D questionnaire to assess health-related quality of life (HRQoL) in…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:30

M
pubmed: "oral oncol"[jour]Continuing education in oral cancer during coronavirus disease 2019 (covid-19) outbreak.Related ArticlesContinuing education in oral cancer during coronavirus disease 2019 (covid-19) outbreak. Oral Oncol. 2020 Apr 16;:104713 Authors: da Cruz Perez DE, Passos KKM, Machado RA, Martelli-Junior H, Bonan PRF PMID: 32307326 [PubMed – as supplied by publisher]pubmed: "oral oncol"[jour]19hMark above section as read ScienceDirect Publication: International Journal of Biological…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:29

M
Experimental Cell ResearchAlterations in osteocyte mediated osteoclastogenesis during estrogen deficiency and under ROCK-II inhibition: An <em>in vitro</em> study using a novel postmenopausal multicellular niche modelPublication date: Available online 21 April 2020Source: Experimental Cell ResearchAuthor(s): Irene Simfia, Jessica Schiavi, Laoise M. McNamaraExperimental Cell Research17hLong non-coding RNA HNF1A-AS1 upregulates OTX1 to enhance angiogenesis in colon cancer via the binding…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:27

M
edoc: No conditions. Results ordered -Date Deposited.Long-Lived Particles at the Energy Frontier: The MATHUSLA Physics CaseWe examine the theoretical motivations for long-lived particle (LLP) signals at the LHC in a comprehensive survey of standard model (SM) extensions. LLPs are a common prediction of a wide range of theories that address unsolved fundamental mysteries such as naturalness, dark matter, baryogenesis and neutrino masses, and represent a natural and generic possibility for physics…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:25

M
Proceedings of the National Academy of Sciences current issueGene drive and resilience through renewal with next generation Cleave and Rescue selfish genetic elements [Genetics]Gene drive-based strategies for modifying populations face the problem that genes encoding cargo and the drive mechanism are subject to separation, mutational inactivation, and loss of efficacy. Resilience, an ability to respond to these eventualities in ways that restore population modification with functional genes, is…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:24

Predictors for Short-Term Efficacy of Allergen-Specific Sublingual Immunotherapy in Children with Allergic Rhinitis
Predictors for Short-Term Efficacy of Allergen-Specific Sublingual Immunotherapy in Children with Allergic Rhinitis: Background.A good compliance in allergen-specific sublingual immunotherapy (SLIT) often comes from good short-term efficacy. We aimed to evaluate the pretreatment parameters which can predict the short-term clinical efficacy in children that underwent SLIT. Methods. 517 children with allergic rhinitis (AR) that underwent SLIT were recruited in this study. Baseline clinical characteristics…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:01

M
Hindawi Publishing CorporationMeasuring the Energy and Carbon Emission Efficiency of Regional Transportation Systems in China: Chance-Constrained DEA ModelsIn China, the transportation sector contributes about 18% of the total carbon emissions. This research contributes to measuring the energy and carbon emission efficiency (ECEE) of regional transportation systems (RTS) in China considering uncertain carbon emissions. A radial chance-constrained data envelopment analysis (DEA) model is developed…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:01

Clinical Manifestations, Diagnosis, and Surgery of Inferior Oblique Muscle Ectopia
Clinical Manifestations, Diagnosis, and Surgery of Inferior Oblique Muscle Ectopia: Objectives. To summarize the clinical manifestations, diagnosis, treatment, and prognosis for inferior oblique muscle ectopia (IO-E). Subjects and Methods. Patients diagnosed with IO-E during strabismus surgery from March 2017 to September 2018 were included in this retrospective, cross-sectional study. All patients received preoperative Krimsky test, synoptophore, cycloplegia refraction, fundus torsion, and other…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:00

M
Latest ResultsTargeting c-Met in triple negative breast cancer: preclinical studies using the c-Met inhibitor, Cpd ASummary Introduction Triple negative breast cancer (TNBC) represents a heterogeneous subtype of breast cancer that carries a poorer prognosis. There remains a need to identify novel drivers of TNBC, which may represent targets to treat the disease. c-Met overexpression is linked with decreased survival and is associated with the basal subtype of breast cancer. Cpd A, a kinase inhibitor…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:46

Treating thyroid nodules by radiofrequency: is the delivered energy correlated with the volume reduction rate? A pilot study
Treating thyroid nodules by radiofrequency: is the delivered energy correlated with the volume reduction rate? A pilot study: AbstractObjectiveRadiofrequency ablation (RFA) was proven as effective in reducing thyroid nodules’ volume. However, whether technical procedure aspects could influence the volume reduction rate (VRR) has not been clarified. This retrospective pilot study aimed to analyze the correlation of RFA power, duration, and energy with VRR.MethodsDuring the period from June to December…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:45

M
Cancer Biotherapy & Radiopharmaceuticals – Table of Contents89Zr-Labeled Anti-PD-L1 Antibody Fragment for Evaluating In Vivo PD-L1 Levels in Melanoma Mouse ModelCancer Biotherapy and Radiopharmaceuticals, Ahead of Print.Cancer Biotherapy & Radiopharmaceuticals – Table of Contents1hLong Noncoding RNA HOTAIR Contributes to Progression in Hepatocellular Carcinoma by Sponging miR-217-5pCancer Biotherapy and Radiopharmaceuticals, Ahead of Print.Cancer Biotherapy & Radiopharmaceuticals – Table…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:44

Efficacy and Safety of Galcanezumab for the Preventive Treatment of Migraine: A Narrative Review
Efficacy and Safety of Galcanezumab for the Preventive Treatment of Migraine: A Narrative Review: AbstractMigraine is a debilitating neurologic disease. People who experience migraine can have substantial disability, impaired functioning and a decreased quality of life (QoL). Expert recommendations suggest that people with frequent migraine attacks or severe impairment related to attacks may benefit from preventive treatment. Despite these recommendations and the existence of evidence-based guidelines…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:43

Pharmacokinetics and Safety of Posaconazole Tablet Formulation in Chinese Participants at High Risk for Invasive Fungal Infection
Pharmacokinetics and Safety of Posaconazole Tablet Formulation in Chinese Participants at High Risk for Invasive Fungal Infection: AbstractIntroductionThis study characterized the multidose pharmacokinetic (PK) characteristics of posaconazole tablets used as prophylactic antifungal therapy in Chinese patients with acute myelogenous leukemia (AML) at risk for invasive fungal infection (IFI).MethodsParticipants in this open-label, single-arm, phase 1b study received posaconazole 300 mg twice daily…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:43

M
CancerNetworkPhase III CheckMate-9ER Trial Meets Primary Endpoint in Advanced RCC TrialThe trial evaluated nivolumab in combination with cabozantinib compared to sunitinib in previously untreated advanced or metastatic renal cell carcinoma, meeting its primary endpoint of progression-free survival at final analysis. (Source: CancerNetwork)CancerNetwork9mILROG Recommends Alternative Radiation Treatment Schemes in Blood Cancer During COVID-19 PandemicThe International Lymphoma Radiation Oncology Group…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

08:42

Medicine
S ScienceDirect Publication: European Annals of Otorhinolaryngology, Head and Neck DiseasesGuidelines of clinical practice for the management of swallowing disorders and recent dysphonia in the contexte of the COVID-19 pandemicPublication date: Available online 20 April 2020Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): A. Mattei, B Amy de la Bretèque, S. Crestani, L. Crevier-Buchman, C. Galant, S. Hans, A. Julien-Laferrière, A. Lagier, C. Lobryeau, F. Marmouset,…Medicine…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

Tue Apr 21, 2020 09:04

Head and neck squamous cell cancer associated with lymphoproliferative malignancies is aggressive.
Head and neck squamous cell cancer associated with lymphoproliferative malignancies is aggressive.: Related ArticlesHead and neck squamous cell cancer associated with lymphoproliferative malignancies is aggressive.J Laryngol Otol. 2020 Apr 20;:1-3Authors: Li L, Hamilton L, Montgomery J, Stewart MAbstract BACKGROUND: Patients with non-Hodgkin’s lymphoma and chronic lymphocytic leukaemia are at an elevated risk of further malignancy. Head and neck squamous cell carcinoma often presents with…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:54

Potential of Pembrolizumab in Metastatic or Recurrent Head and Neck Cancer: Evidence to Date.
Potential of Pembrolizumab in Metastatic or Recurrent Head and Neck Cancer: Evidence to Date.: Related ArticlesPotential of Pembrolizumab in Metastatic or Recurrent Head and Neck Cancer: Evidence to Date.Onco Targets Ther. 2020;13:3047-3059Authors: McCusker MG, Orkoulas-Razis D, Mehra RAbstract Relapsed and/or metastatic head and neck squamous cell carcinoma (R/M HNSCC) is a heterogeneous disease previously associated with poor prognosis and limited treatment options until the advent and…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:54

Chronic and Severe Non-Lichenoid Oral Ulcers Induced by Nivolumab – Diagnostic and Therapeutic Challenge: A Case Report.
Chronic and Severe Non-Lichenoid Oral Ulcers Induced by Nivolumab – Diagnostic and Therapeutic Challenge: A Case Report.: Related ArticlesChronic and Severe Non-Lichenoid Oral Ulcers Induced by Nivolumab – Diagnostic and Therapeutic Challenge: A Case Report.Case Rep Oncol. 2020 Jan-Apr;13(1):314-320Authors: Cardona AF, Ruiz-Patiño A, Ricaurte L, Zatarain-Barrón ZL, Barrón F, Arrieta OAbstract Due to the widespread use of immune checkpoint inhibitors and the growing research efforts in this…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:54

The Carit Maneuver: A Novel Approach for the Relief of Shoulder Dystocia-A Case Series.
The Carit Maneuver: A Novel Approach for the Relief of Shoulder Dystocia-A Case Series.: https://www.researchgate.net/publication/340673646_The_Carit_Maneuver_A_Novel_Approach_for_the_Relief_of_Shoulder_Dystocia-A_Case_Series/fulltext/5e99732d4585150839e3ba09/The-Carit-Maneuver-A-Novel-Approach-for-the-Relief-of-Shoulder-Dystocia-A-Case-Series.pdfRelated ArticlesThe Carit Maneuver: A Novel Approach for the Relief of Shoulder Dystocia-A Case Series.AJP Rep. 2020 Apr;10(2):e133-e138Authors: Gei AF,…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:53

Risk of head and neck cancer after chronic pancreatitis.
Risk of head and neck cancer after chronic pancreatitis.: Related ArticlesRisk of head and neck cancer after chronic pancreatitis.Ann Transl Med. 2020 Mar;8(5):213Authors: Chen CH, Chen CH, Lin CL, Hsu CY, Kao CHAbstractBackground: To evaluate the relation of head and neck cancer to chronic pancreatitis by analyzing Taiwan’s National Health Insurance Research Database.Methods: We identified 11,237 patients with chronic pancreatitis as the case cohort, which was propensity score matched with another…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:50

Remove ads


Comparison of Systemic EBV-positive T-Cell and NK-Cell Lymphoproliferative Diseases of Childhood Based on Classification Evolution: New Classification, Old Problems
Comparison of Systemic EBV-positive T-Cell and NK-Cell Lymphoproliferative Diseases of Childhood Based on Classification Evolution: New Classification, Old Problems: Systemic Epstein-Barr virus–positive T-cell and natural killer (NK)-cell lymphoproliferative diseases of childhood are a group of lethal diseases mostly affecting children and young adults. The Ohshima Grading System and the 2017 World Health Organization (WHO) classification have been used for classifying this spectrum, but these systems…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:42

Pregnancy-associated Inflammatory Myofibroblastic Tumors of the Uterus Are Clinically Distinct and Highly Enriched for TIMP3-ALK and THBS1-ALK Fusions
Pregnancy-associated Inflammatory Myofibroblastic Tumors of the Uterus Are Clinically Distinct and Highly Enriched for TIMP3-ALK and THBS1-ALK Fusions: As inflammatory myofibroblastic tumors (IMTs) have become more widely recognized in the female genital tract, an intriguing subset of uterine tumors associated with pregnancy has emerged. Whether uterine IMTs occurring in the setting of pregnancy are clinically or biologically distinct from other uterine IMTs is unknown. Furthermore, little is known…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:41

Primary Vascular Tumors of Bone: A Monoinstitutional Morphologic and Molecular Analysis of 427 Cases With Emphasis on Epithelioid Variants
Primary Vascular Tumors of Bone: A Monoinstitutional Morphologic and Molecular Analysis of 427 Cases With Emphasis on Epithelioid Variants: Recent molecular discoveries have refined vascular bone tumor classification. To investigate the clinical relevance of these refinements, we reviewed all cases of primary vascular bone tumors treated at our Institute. On the basis of morphology, cases were assessed immunohistochemically and molecularly. A total of 427 cases of primary vascular tumor of bone with…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:41

Primary Cutaneous CD4+ Small/Medium T-Cell Lymphoproliferative Disorders: A Clinical, Pathologic, and Molecular Study of 60 Cases Presenting With a Single Lesion: A Multicenter Study of the French Cutaneous Lymphoma Study Group
Primary Cutaneous CD4+ Small/Medium T-Cell Lymphoproliferative Disorders: A Clinical, Pathologic, and Molecular Study of 60 Cases Presenting With a Single Lesion: A Multicenter Study of the French Cutaneous Lymphoma Study Group: Primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder (PCSMLPD) is a recently recognized entity in the 2017 World Health Organization (WHO) classification. It belongs to the T-follicular helper (TFH) lymphoproliferations. The clinical, pathologic, and molecular…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:41

Follicular Thyroid Neoplasms: Comparison of Clinicopathologic and Molecular Features of Atypical Adenomas and Follicular Thyroid Carcinomas
Follicular Thyroid Neoplasms: Comparison of Clinicopathologic and Molecular Features of Atypical Adenomas and Follicular Thyroid Carcinomas: In follicular thyroid neoplasms without invasion, a diagnosis of atypical adenoma (AA) (follicular tumor of uncertain malignant potential) may be rendered if atypical features (indefinite capsular/vascular invasion, necrosis, solid growth, increased mitoses) are present. This study compares clinical, histologic, and molecular features of patients with AAs (n=31),…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:41

Prostatic Metaplasia of the Vagina and Uterine Cervix: An Androgen-associated Glandular Lesion of Surface Squamous Epithelium
Prostatic Metaplasia of the Vagina and Uterine Cervix: An Androgen-associated Glandular Lesion of Surface Squamous Epithelium: Prostatic-type differentiation in the lower female genital tract is encountered rarely and its causes and clinical associations are not well established. Within the vagina, reports to date have invariably described ectopic prostatic-type differentiation as restricted to the lamina propria. We recently encountered a patient receiving testosterone for gender dysphoria whose…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:40

A Modified Histopathologic Staging in Penile Squamous Cell Carcinoma Predicts Nodal Metastasis and Outcome Better Than the Current AJCC Staging
A Modified Histopathologic Staging in Penile Squamous Cell Carcinoma Predicts Nodal Metastasis and Outcome Better Than the Current AJCC Staging: Recently, the American Joint Committee on Cancer (AJCC) updated the staging system for penile squamous cell carcinoma. According to it, unlike its previous version, the involvement of urethra does not upstage the tumor; however, the involvement of corpora cavernosa (CC) does. The tumors involving CC are now staged pT3, whereas those involving corpora spongiosa…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:40

Gastrointestinal Malakoplakia: Clinicopathologic Analysis of 26 Cases
Gastrointestinal Malakoplakia: Clinicopathologic Analysis of 26 Cases: Malakoplakia is an inflammatory process related to defective macrophage response to bacterial infection. To further characterize the clinicopathologic manifestations of gastrointestinal malakoplakia, 26 cases were identified from 6 institutions. Hematoxylin and eosin-stained slides and available stains were reviewed, and pertinent clinicopathologic features analyzed. Sixteen patients were women (62%). Mean patient age was 64 (range:…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:40

Comparison of Systemic EBV-positive T-Cell and NK-Cell Lymphoproliferative Diseases of Childhood Based on Classification Evolution: New Classification, Old Problems
Comparison of Systemic EBV-positive T-Cell and NK-Cell Lymphoproliferative Diseases of Childhood Based on Classification Evolution: New Classification, Old Problems: Systemic Epstein-Barr virus–positive T-cell and natural killer (NK)-cell lymphoproliferative diseases of childhood are a group of lethal diseases mostly affecting children and young adults. The Ohshima Grading System and the 2017 World Health Organization (WHO) classification have been used for classifying this spectrum, but these systems…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:39

Apocrine Variant of Pleomorphic Lobular Carcinoma In Situ: Further Clinical, Histopathologic, Immunohistochemical, and Molecular Characterization of an Emerging Entity
Apocrine Variant of Pleomorphic Lobular Carcinoma In Situ: Further Clinical, Histopathologic, Immunohistochemical, and Molecular Characterization of an Emerging Entity: To date, the apocrine variant of lobular carcinoma in situ (AP-LCIS) has been cursorily described as a subtype of lobular carcinoma in situ (LCIS). We retrospectively reviewed 34 cases of AP-LCIS (including 23 associated with invasive lobular carcinoma) to fully characterize it. AP-LCIS typically presented with screen-detected calcifications…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:39

Skin-Colored Nodule on the Cutaneous Lip: Challenge
Skin-Colored Nodule on the Cutaneous Lip: Challenge:

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:38

A Fatal Infection With Subtle and Nonspecific Signs and Symptoms in a Neonate: Challenge
A Fatal Infection With Subtle and Nonspecific Signs and Symptoms in a Neonate: Challenge:

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:36

Brownish and Indurated Plaques With Yellowish Papules: Challenge
Brownish and Indurated Plaques With Yellowish Papules: Challenge: No abstract available

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:34

M
AUD : Last 20 articlesEffect of Noise Exposure on 1,382 Metallurgical Workers in Periodic Audiometric Evaluation: A Cohort StudyIntroduction: Noise-induced hearing loss is the most preventable cause of auditory impairment. Periodic audiometric evaluations are essential to monitor the hearing health of noise-exposed workers. Objective: To compare the evolution of audiometric thresholds in the initial three evaluations at frequencies of 3, 4, and 6 kHz in groups of workers exposed or not to noise….

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:33

M
pubmed: sleepInvestigation and diagnostic imaging of suspected pulmonary embolism during pregnancy and the puerperium: A review of the literature.Related ArticlesInvestigation and diagnostic imaging of suspected pulmonary embolism during pregnancy and the puerperium: A review of the literature. J Med Imaging Radiat Oncol. 2020 Apr 20;: Authors: Tester J, Hammerschlag G, Irving L, Pascoe D, Rees M Abstract Pulmonary embolism (PE) is a leading cause of maternal mortality with women at increased risk…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:32

M
AA pubmed: head and neckOsteopromotive carbon dots promote bone regeneration through the PERK-eIF2α-ATF4 pathway.Related ArticlesOsteopromotive carbon dots promote bone regeneration through the PERK-eIF2α-ATF4 pathway. Biomater Sci. 2020 Apr 20;: Authors: Jin N, Jin N, Wang Z, Liu L, Meng L, Li D, Li X, Zhou D, Liu J, Bu W, Sun H, Yang B Abstract Bone defects are still an unsolved clinical issue that must be overcome. Carbon dots have shown very promising effects in biological therapy. In the current…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:31

M
pubmed: philosophy for medic…Long-term outcomes after childhood convulsive status epilepticus.Related ArticlesLong-term outcomes after childhood convulsive status epilepticus. Curr Opin Pediatr. 2019 12;31(6):763-768 Authors: Pujar S, Scott RC Abstract PURPOSE OF REVIEW: It is widely accepted that childhood convulsive status epilepticus (CSE) has associated short-term and long-term mortality and morbidity. However, the role of CSE itself on subsequent adverse outcomes is still debated. In addition,…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:29

Remove ads


M
ScienceDirect Publication: Cell ReportsBeta-Catenin Causes Adrenal Hyperplasia by Blocking Zonal TransdifferentiationPublication date: 21 April 2020Source: Cell Reports, Volume 31, Issue 3Author(s): Emanuele Pignatti, Sining Leng, Yixing Yuchi, Kleiton S. Borges, Nick A. Guagliardo, Manasvi S. Shah, Gerard Ruiz-Babot, Dulanjalee Kariyawasam, Makoto Mark Taketo, Ji Miao, Paula Q. Barrett, Diana L. Carlone, David T. BreaultScienceDirect Publication: Cell Reports18hProfiling of Small Ribosomal Subunits…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:27

M
edoc: No conditions. Results ordered -Date Deposited.The ABC taxonomy for medication adherence translated into French and GermanWe translated the ABC adherence taxonomy (i.e., seven terms and their corresponding definitions) published by Vrijens et al. (2012) into French (F) and German (G) without changing the original meaning with the aim to promote a standardised taxonomy for medication adherence to French- and German-speaking researchers and clinicians.; A Delphi survey was performed. To generate…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:26

M
Emergency Medicine Journal Online FirstPrognostic accuracy of the quick Sequential Organ Failure Assessment (qSOFA)-lactate criteria for mortality in adults with suspected bacterial infection in the emergency department of a hospital with limited resourcesBackgroundRoutine use of the Sequential Organ Failure Assessment (SOFA) score to prognosticate patients with sepsis is challenged by the requirement to perform numerous laboratory tests. The prognostic accuracy of the quick SOFA (qSOFA) without…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:25

M
Proceedings of the National Academy of Sciences current issueReply to Nock and Nielsen: On the work of Nock and Nielsen and its relationship to the additive tree [Physical Sciences]The observation that decision trees are boosting algorithms, as cited in our work (1) and acknowledged by Nock and Nielsen (2), was first established by refs. 3 and 4. This was later used by refs. 5 and 6 to develop, to the best of our knowledge, the first decision tree…Proceedings of the National Academy of Sciences…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:22

M
Clinical Oral InvestigationsThe efficacy of different cleaning protocols for the sealer-contaminated access cavityAbstract Objectives Sealer remnants in the access cavity may negatively affect coronal seal and cause tooth discoloration. This study sought to evaluate the efficacy of different cleaning protocols for the sealer-contaminated access cavity. Materials and methods Sixty extracted human molars were accessed, chemomechanically prepared and warm vertically obturated…Clinical Oral Investigations11hMark…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:21

M
Journal of Plastic, Reconstructive & Aesthetic SurgeryA plastic surgery service response to COVID-19 in one of the largest teaching hospitals in EuropeCOVID-19 is presenting a colossal challenge to frontline NHS staff. This paper highlights how plastic surgery teams can use their diverse skills and resources in times of crisis. Through effective strategy and leadership we present how we are adapting as a department to serve our plastic surgery patients, other hospital teams and the Trust.Journal…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:20

M
Planta MedicaIdentification and α-Glucosidase Inhibitory Activity of Meroterpenoids from Hericium erinaceusPlanta MedDOI: 10.1055/a-1146-8369 Hericium erinaceus is a very popular edible and medicinal mushroom used for the treatment of enervation and gastrointestinal diseases in Eastern Asia. Chemical investigation on the fruiting body of Hericium erinaceus led to the isolation of 4 new (1 – 4) and 10 known meroterpenoids (5 – 14). The structures of new compounds were determined via analysis of NMR…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:18

M
Latest ResultsRadiolytic degradation of chlorobenzene in aerated and deoxygenated aqueous solutionsAbstract Radiation-induced degradation of chlorobenzene was conducted at 0.1, 0.4, 0.5, 0.7, and 1.0 mmol/dm3 concentrations in aerated environment and at 1.0 mmol/dm3 in oxygen-free and N2O-saturated solutions. The results demonstrated that the elimination of chloride is important when the solution is oxygen free, because the \( {\mathrm{e}}_{\mathrm{aq}}^{-} \) attacks at the ipso position of the…

Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

09:16

#
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia,

Telephone consultation 11855 int 1193,

Medicine

S
ScienceDirect Publication: European Annals of Otorhinolaryngology, Head and Neck DiseasesGuidelines of clinical practice for the management of swallowing disorders and recent dysphonia in the contexte of the COVID-19 pandemicPublication date: Available online 20 April 2020Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): A. Mattei, B Amy de la Bretèque, S. Crestani, L. Crevier-Buchman, C. Galant, S. Hans, A. Julien-Laferrière, A. Lagier, C. Lobryeau, F. Marmouset,…

Medicine by Alexandros G. Sfakianakis

08:58

M
BMJ QIR Current IssueImproving patient safety during intrahospital transportation of mechanically ventilated patients with critical illnessAimIntrahospital transportation (IHT) of patients under mechanical ventilation (MV) significantly increases the risk of patient harm. A structured process performed by a well-prepared team with adequate communication among team members plays a vital role in enhancing patient safety during transportation. Design and implementationWe conducted this quality improvement…

Medicine by Alexandros G. Sfakianakis

08:45

Liposarcoma of oral cavity: Systematic review of cases reported to date and analysis of prognostic factors
Liposarcoma of oral cavity: Systematic review of cases reported to date and analysis of prognostic factors: AbstractThe aim of this study was to integrate the available data published on Liposarcomas (LPSs) of the oral cavity into an analysis of its clinical features, treatment modalities, and prognostic factors. An electronic search was undertaken in January 2019. The eligibility criteria included publications that had enough clinical and histological information to confirm the diagnosis. Forty‐five…

Medicine by Alexandros G. Sfakianakis

08:41

Intravascular large B‐cell lymphoma presenting as a nondescript macular eruption
Intravascular large B‐cell lymphoma presenting as a nondescript macular eruption:

Medicine by Alexandros G. Sfakianakis

08:40

Dietary habits in Japanese patients with chronic spontaneous urticaria
Dietary habits in Japanese patients with chronic spontaneous urticaria: AbstractBackgroundChronic spontaneous urticaria (CSU) is defined as the spontaneously appearing weals and/or angioedema for more than 6 weeks. Dietary habits can modulate the pathogenesis of CSU. However, dietary intakes of nutrients or food in CSU patients, compared with healthy controls, have not been examined in quality and quantity.MethodsWe evaluated dietary habits in adult Japanese patients with chronic spontaneous urticaria…

Medicine by Alexandros G. Sfakianakis

08:40

Autoimmune progesterone dermatitis presenting as recurrent, marked angioedema‐like lip changes: An unusual presentation of an uncommon problem
Autoimmune progesterone dermatitis presenting as recurrent, marked angioedema‐like lip changes: An unusual presentation of an uncommon problem: AbstractAutoimmune progesterone dermatitis is a rare condition with varying clinical presentations. We present a case of autoimmune progesterone dermatitis presenting as recurrent, marked angioedema‐like lip swelling without any other skin changes.

Medicine by Alexandros G. Sfakianakis

08:39

M
BMC Research Notes – Latest ArticlesPatient satisfaction and quality of life in breast reconstruction: assessment of outcomes of immediate, delayed, and nonreconstructionThis study was conducted aiming to assess the quality of life and satisfaction of women who had mastectomy treated with and without breast reconstruction.BMC Research Notes – Latest Articles16hLighter serum copper isotopic composition in patients with early non-alcoholic fatty liver diseaseThe occurrence of non-alcoholic fatty liver…

Medicine by Alexandros G. Sfakianakis

08:38

Antibiotics, Vol. 9, Pages 193: Management of a Case of Peritonitis Due to Neisseria gonorrhoeae Infection Following Pelvic Inflammatory Disease (PID)
Antibiotics, Vol. 9, Pages 193: Management of a Case of Peritonitis Due to Neisseria gonorrhoeae Infection Following Pelvic Inflammatory Disease (PID): Antibiotics, Vol. 9, Pages 193: Management of a Case of Peritonitis Due to Neisseria gonorrhoeae Infection Following Pelvic Inflammatory Disease (PID)Antibiotics doi: 10.3390/antibiotics9040193Authors: Maria A. De Francesco Paola Stefanelli Anna Carannante Silvia Corbellini Cinzia Giagulli Giovanni Lorenzin Maurizio Ronconi …

Medicine by Alexandros G. Sfakianakis

08:36

S
Latest Results for Canadian Journal of Anesthesia/Journal canadien d’anesthésiePractical recommendations for critical care and anesthesiology teams caring for novel coronavirus (2019-nCoV) patientsAbstract A global health emergency has been declared by the World Health Organization as the 2019-nCoV outbreak spreads across the world, with confirmed patients in Canada. Patients infected with 2019-nCoV are at risk for developing respiratory failure and requiring admission to critical care units. While…

Medicine by Alexandros G. Sfakianakis

08:34

Dry eye induced by exposure to cigarette smoke pollution: An in vivo and in vitro study
Dry eye induced by exposure to cigarette smoke pollution: An <em>in vivo</em> and <em>in vitro</em> study: Publication date: Available online 19 April 2020Source: Free Radical Biology and MedicineAuthor(s): Juan Li, Shen Nian, Yi Shao, Guangwei Zhang, Rongbin Liang, Lihua Huang, Ali Luo

Medicine by Alexandros G. Sfakianakis

08:32

Therapeutic potential of ciclesonide inahalation for COVID-19 pneumonia: Report of three cases
Therapeutic potential of ciclesonide inahalation for COVID-19 pneumonia: Report of three cases: Publication date: Available online 16 April 2020Source: Journal of Infection and ChemotherapyAuthor(s): Keisuke Iwabuchi, Koichiro Yoshie, Yuichi Kurakami, Kota Takahashi, Yoshio Kato, Tsuneo MorishimaΣικλεσονίδηΜοιραστείτε Ευρετήριο ΑναφορέςΔραστική ουσία – Γενικές πληροφορίεςΓενικάΧορήγησηΠροφυλάξειςΦαρμακολογίαΔιάθεσηΟνομασίεςΕλληνικάΣικλεσονίδηΕλληνικάΚικλεσονίδηΑγγλικάCiclesonideΣύντομη περιγραφήΗ…

Medicine by Alexandros G. Sfakianakis

08:31

The effect of Tegaderm™ versus EyeGard® on eyelid erythema during general anesthesia: a randomized-controlled trial
The effect of Tegaderm™ versus EyeGard® on eyelid erythema during general anesthesia: a randomized-controlled trial: AbstractPurposeApplication of adhesive tape to the eyelids during general anesthesia decreases the risk of corneal abrasion but may increase the risk of eyelid injury. The aim of this study was to determine if there is a difference in eyelid erythema when covering the eyelid with either Tegaderm™ or an EyeGard®.MethodsWe conducted a prospective, randomized, double-blind, split-face…

Medicine by Alexandros G. Sfakianakis

08:29

S
CancersCancers, Vol. 12, Pages 1005: Dysmetabolic Circulating Tumor Cells Are Prognostic in Metastatic Breast CancerCancers, Vol. 12, Pages 1005: Dysmetabolic Circulating Tumor Cells Are Prognostic in Metastatic Breast Cancer Cancers doi: 10.3390/cancers12041005 Authors: Giulia Brisotto Eva Biscontin Elisabetta Rossi Michela Bulfoni Aigars Piruska Simon Spazzapan Cristina Poggiana Riccardo Vidotto Agostino Steffan Alfonso Colombatti Wilhelm T. S. Huck Daniela Cesselli Rita Zamarchi Matteo Turetta…

Medicine by Alexandros G. Sfakianakis

08:29

M
Latest Results for Archives of ToxicologyToxicometabolomics of the new psychoactive substances α-PBP and α-PEP studied in HepaRG cell incubates by means of untargeted metabolomics revealed unexpected amino acid adductsAbstract Toxicometabolomics, essentially applying metabolomics to toxicology of endogenous compounds such as drugs of abuse or new psychoactive substances (NPS), can be investigated by using different in vitro models and dedicated metabolomics techniques to enhance the number of relevant…

Medicine by Alexandros G. Sfakianakis

08:27

S
BMJ Open Current IssueEcological study of the association between mental illness with human development, income inequalities and unemployment across OECD countriesObjectivesRecent studies have demonstrated worsened mental health in relatively highly developed countries impacted by social inequalities and unemployment. Here, we investigate (1) whether mental health issues are differently or similarly affected by these social factors and (2) whether their effects on mental health are related or unrelated…

Medicine by Alexandros G. Sfakianakis

08:26

Epstein–Barr virus (EBV) and polyomaviruses are detectable in oropharyngeal cancer and EBV may have prognostic impact
Epstein–Barr virus (EBV) and polyomaviruses are detectable in oropharyngeal cancer and EBV may have prognostic impact: AbstractBackgroundThe etiological role of human papillomavirus (HPV) in oropharyngeal squamous cell carcinoma (OPSCC) is confirmed. However, the role of other oncoviruses in OPSCC is unknown. Materials and methodsA total of 158 consecutive OPSCC patients treated with curative intent were included. DNA extracted from tumor sections was used to detect Epstein–Barr virus (EBV), HPV,…

Medicine by Alexandros G. Sfakianakis

08:24

Urogenital Abnormalities in Adenosine Deaminase Deficiency
Urogenital Abnormalities in Adenosine Deaminase Deficiency: AbstractBackgroundImproved survival in ADA-SCID patients is revealing new aspects of the systemic disorder. Although increasing numbers of reports describe the systemic manifestations of adenosine deaminase deficiency, currently there are no studies in the literature evaluating genital development and pubertal progress in these patients.MethodsWe collected retrospective data on urogenital system and pubertal development of 86 ADA-SCID patients…

Medicine by Alexandros G. Sfakianakis

08:24

S
BMJ Case Reports Last 6 IssuesGuillain-Barre syndrome and posterior reversible leukoencephalopathy syndrome: a rare associationA 69-year-old woman presented with headaches and visual disturbance in the context of marked hypertension secondary to non-compliance with antihypertensive medications. She developed seizures and hyperreflexia, and MRI brain showed changes consistent with posterior reversible encephalopathy syndrome (PRES). She was treated with antihypertensives with the resolution of symptoms….

Medicine by Alexandros G. Sfakianakis

08:23

Fraser Syndrome: A Stumbling Block for the Anaesthesiologist
Fraser Syndrome: A Stumbling Block for the Anaesthesiologist: disorders.eyes.arizona.eduFraser syndrome is a rare genetic disorder characterized by partial webbing of the fingers and/or toes (partial syndactyly), kidney (renal) abnormalities, genital malformations, and/or, in some cases, complete fusion of the eyelids (cryptophthalmos) that may be associated with malformation of the eyes, causing …Fraser Syndrome – NORD (National Organization for Rare …AbstractFraser syndrome is a rare autosomal…

Medicine by Alexandros G. Sfakianakis

08:22

Labyrinthine Fistula-Our Experience at a Tertiary Hospital
Labyrinthine Fistula-Our Experience at a Tertiary Hospital: AbstractThis study has aimed to determine the anatomical site of labyrinthine fistula in patients of chronic suppurative otitis media at our centre. Labyrinthine fistulae (LF) are caused by abnormal communications between the inner ear and surrounding structures resulting in perilymph leakage and hearing loss. Labyrinthine fistula represents as erosive loss of the enchondral bone overlying the semicircular canals without loss of perilymph….

Medicine by Alexandros G. Sfakianakis

08:21

Facial trauma aggravating paediatric orbital cellulitis
Facial trauma aggravating paediatric orbital cellulitis: We describe a case of paediatric orbital cellulitis with subperiosteal abscess following blunt facial trauma. Clinical features of orbital cellulitis developed on day 1 post-trauma. A subperiosteal collection subsequently formed lateral to the globe, causing significant ocular compromise. Surgical drainage and sinus washout were performed via external incisions, with satisfactory outcome. This case highlights how trauma may represent a non-sinogenic…

Medicine by Alexandros G. Sfakianakis

08:20

Guillain-Barre syndrome and posterior reversible leukoencephalopathy syndrome: a rare association
Guillain-Barre syndrome and posterior reversible leukoencephalopathy syndrome: a rare association: A 69-year-old woman presented with headaches and visual disturbance in the context of marked hypertension secondary to non-compliance with antihypertensive medications. She developed seizures and hyperreflexia, and MRI brain showed changes consistent with posterior reversible encephalopathy syndrome (PRES). She was treated with antihypertensives with the resolution of symptoms. Over the following week,…

Medicine by Alexandros G. Sfakianakis

08:20

M
Postgraduate Medical Journal Online FirstCOVID-19 pandemic in India: challenges and silver liningsIndia faces multiple major challenges on the COVID-19 front. It is densely populated: 464 people/km2 compared with Italy’s 206, Spain’s 91, Iran’s 52 and the USA’s 36. It has a huge population: 1380 million (USA 330 million, Iran 83 million, Italy 60 million, Spain 46 million). Social distancing without total shutdowns is unthinkable, especially in the big cities with crowded streets, trains, buses…

Medicine by Alexandros G. Sfakianakis

08:19

Hypothermia induced by quetiapine
Hypothermia induced by quetiapine: An 89-year-old woman was brought to the emergency department, responding only to pain (GCS 6), with a rectal temperature of 28.5°C, hypotension (68/40), bradycardia (35/min) and bradypnoea. The remainder of the examination was unremarkable.She was living at home with her son and a caretaker, confined to bed/wheelchair with a history of Alzheimer’s dementia, falls, hypothyroidism (on replacement), hypertension and chronic atrial fibrillation (AF) (on amlodipine 5…

Medicine by Alexandros G. Sfakianakis

08:19

Immune Profile of the Nasal Mucosa in Patients with Cutaneous Leishmaniasis [Fungal and Parasitic Infections]
Immune Profile of the Nasal Mucosa in Patients with Cutaneous Leishmaniasis [Fungal and Parasitic Infections]: Localized skin lesions are characteristic of cutaneous leishmaniasis (CL); however, Leishmania (Viannia) species, which are responsible for most CL cases in the Americas, can spread systemically, sometimes resulting in mucosal disease. Detection of Leishmania has been documented in healthy mucosal tissues (conjunctiva, tonsils, and nasal mucosa) and healthy skin of CL patients and in individuals…

Medicine by Alexandros G. Sfakianakis

08:18

Mesalamine-induced eosinophilic pleural effusion
Mesalamine-induced eosinophilic pleural effusion: A 45-year-old woman with a medical history of ulcerative colitis (UC) presented with difficulty in breathing. The patient was diagnosed with UC a month prior to presentation and was started on mesalamine suppository. Chest x-ray (CXR) on presentation showed bilateral pleural effusion, which was confirmed on CT angiogram of the chest. Diagnostic and therapeutic thoracentesis was performed and 0.7 L of pleural fluid was removed from the left side. The…

Medicine by Alexandros G. Sfakianakis

08:18

Endoscopy-assisted removal of angle foreign body presenting as persistent localised corneal oedema
Endoscopy-assisted removal of angle foreign body presenting as persistent localised corneal oedema: A 20-year-old man presented to us with injury to the left eye by a glass bulb 3 weeks ago. The acute injury resolved with a peculiar residual localised corneal oedema in the inferior one-third of the cornea . This localised oedema in absence of any evidence of a localised visible injury to the cornea indicated towards a possible retained foreign body. The foreign body visibility was equivocal on gonioscopy….

Medicine by Alexandros G. Sfakianakis

08:17

S
Latest ResultsClinical characteristics and outcomes of oligosecretory and non-secretory multiple myelomaAbstract Secretion of monoclonal immunoglobulins (MIg) detected in the serum and/or urine is one of the typical features of multiple myeloma (MM). However, some patients secrete MIg in quantities below “measurable” (termed oligosecretory MM) and others have no detectable MIgs by standard serum and urine immunofixation (termed non-secretory MM). In a cohort of 852 consecutive patients with active…

Medicine by Alexandros G. Sfakianakis

08:16

Propranolol-induced acneiform eruptions: revisiting a rare cutaneous side effect
Propranolol-induced acneiform eruptions: revisiting a rare cutaneous side effect: Propranolol is a frequently prescribed non-selective beta-blocker for the management of hypertension, cardiac arrhythmias, post myocardial infarction, thyrotoxicosis, tremors and migraine prophylaxis.1 Although rare, it may produce dermatological side effects like exacerbation of psoriasis, atopic dermatitis, alopecia and lupus erythematosus reactions.2 Here we describe a case of propranolol-induced acneiform eruption…

Medicine by Alexandros G. Sfakianakis

08:15

M
PLOS Pathogens: New ArticlesContribution of STAT1 to innate and adaptive immunity during type I interferon-mediated lethal virus infectionby So Ri Jung, Thomas M. Ashhurst, Phillip K. West, Barney Viengkhou, Nicholas J. C. King, Iain L. Campbell, Markus J. Hofer Signal transducers and activators of transcription (STAT) 1 is critical for cellular responses to type I interferons (IFN-Is), with the capacity to determine the outcome of viral infection. We previously showed that while wildtype (WT) mice…

Medicine by Alexandros G. Sfakianakis

08:13

S
Nucleic Acid Therapeutics – Table of ContentsPharmacodynamic and Pharmacokinetic Properties of Full Phosphorothioate Small Interfering RNAs for Gene Silencing In VivoNucleic Acid Therapeutics, Ahead of Print.Nucleic Acid Therapeutics – Table of ContentsnowMark above section as read Annals of Nuclear MedicineAI approach of cycle-consistent generative adversarial networks to synthesize PET images to train computer-aided diagnosis algorithm for dementiaAbstract Objective An artificial intelligence…

Medicine by Alexandros G. Sfakianakis

08:11

M
JBC Papers in PressTargeting the ABC transporter ABCB5 sensitizes glioblastoma to temozolomide-induced apoptosis through a cell-cycle checkpoint regulation mechanism [Molecular Bases of Disease]Glioblastoma multiforme (GBM) is a malignant brain tumor with a poor prognosis resulting from tumor resistance to anticancer therapy and a high recurrence rate. Compelling evidence suggests that this is driven by subpopulations of cancer stem cells (CSCs) with tumor-initiating potential. ATP-binding cassette…

Medicine by Alexandros G. Sfakianakis

08:10

S
Cancer Research Online First ArticlesTumor cell-derived Angiopoietin-2 promotes metastasis in melanomaThe Angiopoietin (Angpt)-TIE signaling pathway controls vascular maturation and maintains the quiescent phenotype of resting vasculature. The contextual agonistic and antagonistic Tie2 ligand ANGPT2 is believed to be exclusively produced by endothelial cells, disrupting constitutive ANGPT1-TIE2 signaling to destabilize the microvasculature during pathological disorders like inflammation and cancer….

Medicine by Alexandros G. Sfakianakis

08:08

M
Hindawi Publishing CorporationLimb Ischemic Postconditioning Alleviates Postcardiac Arrest Syndrome through the Inhibition of Mitochondrial Permeability Transition Pore Opening in a Porcine ModelObjective. Previously, the opening of mitochondrial permeability transition pore (mPTP) was confirmed to play a key role in the pathophysiology of postcardiac arrest syndrome (PCAS). Recently, we demonstrated that limb ischemic postconditioning (LIpostC) alleviated cardiac and cerebral injuries after cardiac…

Medicine by Alexandros G. Sfakianakis

08:07

S
Hindawi Publishing CorporationVariable Load Demand Scheme for Hybrid AC/DC NanogridThis paper addresses the use of nanogrid technology in resolving the issue of blanket load shedding for domestic consumers. This is accomplished by using different load management techniques and load classification and utilizing maximum solar energy. The inclusion of DC-based load in basic load and DC inverter load in regular load and scheduling of the burst load during the hours of maximum solar PV generation bring…

Medicine by Alexandros G. Sfakianakis

08:05

Decreased Plasma Maresin 1 Concentration Is Associated with Diabetic Foot Ulcer
Decreased Plasma Maresin 1 Concentration Is Associated with Diabetic Foot Ulcer: Aims. To assess the maresin 1 (MaR1) contents in type 2 diabetic patients with or without diabetic foot ulcer and to analyze the association of MaR1 concentrations with several metabolism-related parameters. Methods. Plasma MaR1 concentrations were analyzed in 96 subjects with normal glucose tolerant (NC, ), type 2 diabetes (T2DM, ), or diabetic foot ulcer (DFU, ). The intravenous glucose tolerance test (IVGTT) and biochemical…

Medicine by Alexandros G. Sfakianakis

08:04

Paediatric Posttraumatic Cyst-Like Lesions: A Report of Two Cases and Review of the Literature
Paediatric Posttraumatic Cyst-Like Lesions: A Report of Two Cases and Review of the Literature: Posttraumatic cyst-like lesions are a rare finding after greenstick fractures in children. These asymptomatic, cystic lesions become radiologically apparent 2-4 months after the initial trauma. Conventional radiographs typically show nonexpansile, well-circumscribed lesions in the cortex, proximal to the fracture site. It is important to recognize them as benign to prevent unnecessary concern and additional…

Medicine by Alexandros G. Sfakianakis

08:04

The Bethesda System for Reporting Thyroid Cytopathology: . The distribution of cases in various TBSRTC categories is as follows: I—nondiagnostic 13.8%, II—benign 75.9%, III—atypia of undetermined significance (AUS)/follicular lesion of undetermined significance (FLUS) 1.2%, IV—follicular neoplasm (FN)/suspicious for follicular neoplasm (SFN) 3.7%, V—suspicious for malignancy (SM) 2.6%, and VI—malignant 2.8%. The sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy are 72.4%, 94.3%, 84%, 89.2%, and 87.9%, respectively. The ROM of various TBSRTC categories were II—8.5%; III—66.7%; IV—63.6%; and V and VI—100%. Cohen’s Weighted Kappa score was 0.99 which indicates almost perfect agreement among the three pathologists.
The Bethesda System for Reporting Thyroid Cytopathology: A Cytohistological Study: Introduction. The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) is a significant step to standardize the reporting of thyroid fine needle aspiration (FNA). It has high predictive value, reproducibility, and improved clinical significance. Aim. The study was aimed to evaluate the diagnostic utility and reproducibility of “TBSRTC” at our institute. Methods and Material. The study included 646 thyroid FNAs…

Medicine by Alexandros G. Sfakianakis

08:03

M
Latest ResultsDerivation of synthetic fuel from waste plastic: investigation of engine operating characteristics on DI diesel engineAbstract The utilization of plastic in day to day life is ever-increasing and has generated a large amount of plastic garbage that needs proper disposal to save the environment from harmful pollution. The plastic waste management becomes a pressing concern in the present scenario in developing countries like India. This research article evaluates the potential of synthetic…

Medicine by Alexandros G. Sfakianakis

07:57

Remove ads


Efficacy of 0.5% Levofloxacin and 5.0% Povidone-Iodine Eyedrops in Reducing Conjunctival Bacterial Flora: Metagenomic Analysis
Efficacy of 0.5% Levofloxacin and 5.0% Povidone-Iodine Eyedrops in Reducing Conjunctival Bacterial Flora: Metagenomic Analysis: Bacteria associated with postoperative endophthalmitis mostly originate from the normal bacterial flora of the patient’s conjunctiva and eyelids, so the incidence of endophthalmitis may be reduced by eliminating the ocular and adnexal flora before surgery. We assessed the effectiveness of eyedrops of 0.5% levofloxacin and 5.0% povidone-iodine (PVI) in reducing conjunctival…

Medicine by Alexandros G. Sfakianakis

07:57

S
Latest ResultsEcological risk evaluation and source apportionment of heavy metals in park playgrounds: a case study in Xi’an, Shaanxi Province, a northwest city of ChinaAbstract Park playgrounds recently are suffering serious heavy metals contamination in China. It is urgent to assess the ecological risk and identify the sources for heavy metals. A total of 111 topsoil samples were collected from four park playgrounds in Xi’an, and the X-ray fluorescence (XRF) instrument was used to measure the…

Medicine by Alexandros G. Sfakianakis

07:55

M
Latest ResultsElectrical resistivity imaging for detection of hydrogeological active zones in karst areas to identify the site of mining waste disposalAbstract Hydrogeological active zones found in mine waste (tailings) dumping sites are a major source of concern that threatens the safety of the environment and groundwater, especially in karstic areas. Therefore, detecting and identifying these regions correctly will help in selecting the appropriate sites for tailings disposal and avoid consequential…

Medicine by Alexandros G. Sfakianakis

07:54

Cardiac toxicity of acrolein exposure in embryonic zebrafish ( Danio rerio )
Cardiac toxicity of acrolein exposure in embryonic zebrafish ( Danio rerio ): AbstractAcrolein is a widely distributed pollutant produced from various sources such as industrial waste, organic combustion, and power plant emissions. It is also intentionally released into irrigation canals to control invasive aquatic plants. Zebrafish (Danio rerio) has a good reputation for being an attractive model organism for developmental and toxicological research. In this study, zebrafish embryos were exposed…

Medicine by Alexandros G. Sfakianakis

07:53

S
Latest Results for Oral and Maxillofacial SurgeryRetropharyngeal internal carotid artery: a review of three casesAbstract Introduction The internal carotid artery (ICA) can take multiple pathways as it extends from the carotid bifurcation to the skull base. An aberration of its normal pathway may place the ICA in a retropharyngeal position in close proximity to the posterior pharyngeal wall. Radiographic classification is based on its proximity to the pharynx and/or pathway. We present a series…

Medicine by Alexandros G. Sfakianakis

07:53

Role of Molecular Chaperones in Carcinogenesis: Mechanism, Diagnosis, and Treatment
Role of Molecular Chaperones in Carcinogenesis: Mechanism, Diagnosis, and Treatment: The role of molecular chaperones in carcinogenesis is a central theme of many current research efforts worldwide. It is pertinent to clarify that while various chaperones are Hsps, many are not, and vice versa not all Hsps are chaperones. An example of the latter is Hsp32, better known as heme oxygenase-1 (HO-1), which is dealt with in one of the articles in this Special Issue because of its probable involvement…

Medicine by Alexandros G. Sfakianakis

07:52

Novel Approaches for Diagnosing and Management of Cardiovascular Disorders Mediated by Oxidative Stress
Novel Approaches for Diagnosing and Management of Cardiovascular Disorders Mediated by Oxidative Stress: The cardiovascular disease is one of the major healthcare problems of the world population, and understanding its determinants is essential for designing effective interventions.Reactive oxygen species (ROS) are toxic, highly reactive, and unstable compounds formed during a variety of physiological and pathological biochemical reactions. ROS are produced in all viable cells, and strong evidence…

Medicine by Alexandros G. Sfakianakis

07:49

Ocular Findings in the 16p11.2 Microdeletion Syndrome: A Case Report and Literature Review
Ocular Findings in the 16p11.2 Microdeletion Syndrome: A Case Report and Literature Review: The recurrent 16p11.2 microdeletion is characterized by developmental delays and a wide spectrum of congenital anomalies. It has been well reported that individuals with this ∼593-kb interstitial deletion have an increased susceptibility toward the autism spectrum disorder (ASD). Abnormalities of the eye and ocular adnexa are also commonly associated findings seen in individuals with the 16p11.2 microdeletion…

Medicine by Alexandros G. Sfakianakis

07:47

Retropharyngeal internal carotid artery: a review of three cases
Retropharyngeal internal carotid artery: a review of three cases: AbstractIntroductionThe internal carotid artery (ICA) can take multiple pathways as it extends from the carotid bifurcation to the skull base. An aberration of its normal pathway may place the ICA in a retropharyngeal position in close proximity to the posterior pharyngeal wall. Radiographic classification is based on its proximity to the pharynx and/or pathway.We present a series of three cases of retropharyngeal ICAs, our goal is…

Medicine by Alexandros G. Sfakianakis

07:46

M
Obesity ReviewsBody Composition Measurements from Birth through 5 Years: Challenges, Gaps, and Existing & Emerging Technologies—A National Institutes of Health workshopSummary Body composition estimates are widely used in clinical research and field studies as measures of energy‐nutrient balance, functionality and health. Despite their broad relevance and multiple applications, important gaps remain in techniques available for accurately and precisely quantifying body composition in infants…

Medicine by Alexandros G. Sfakianakis

07:45

Lipoteichoic acid of Enterococcus faecalis interferes with Porphyromonas gingivalis lipopolysaccharide signaling via IRAK‐M upregulation in human periodontal ligament cells
Lipoteichoic acid of Enterococcus faecalis interferes with Porphyromonas gingivalis lipopolysaccharide signaling via IRAK‐M upregulation in human periodontal ligament cells: AbstractPeriodontitis is a chronic inflammatory disease of the gums caused by infection with multispecies oral bacteria. Since the periodontopathic bacteria Porphyromonas gingivalis together with Enterococcus faecalis are frequently detected in patients with a severe form of periodontitis, interactions between their virulence…

Medicine by Alexandros G. Sfakianakis

07:43

#
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia,

Telephone consultation 11855 int 1193,

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com, Telephone consultation 11855 int 1193,

Αλέξανδρος Γ. Σφακιανάκης

MD
ScienceDirect Publication: Cell ReportsGlioma-Induced Alterations in Neuronal Activity and Neurovascular Coupling during Disease ProgressionPublication date: 14 April 2020Source: Cell Reports, Volume 31, Issue 2Author(s): Mary Katherine Montgomery, Sharon H. Kim, Athanassios Dovas, Hanzhi T. Zhao, Alexander R. Goldberg, Weihao Xu, Alexis J. Yagielski, Morgan K. Cambareri, Kripa B. Patel, Angeliki Mela, Nelson Humala, David N. Thibodeaux, Mohammed A. Shaik, Ying Ma, Jack Grinband, Daniel S. Chow,…

Αλέξανδρος Γ. Σφακιανάκης

10:53

H&N
AA pubmed: head and neckTumor Biomarkers for the Prediction of Distant Metastasis in Head and Neck Squamous Cell Carcinoma.Related ArticlesTumor Biomarkers for the Prediction of Distant Metastasis in Head and Neck Squamous Cell Carcinoma. Cancers (Basel). 2020 Apr 09;12(4): Authors: Alfieri S, Carenzo A, Platini F, Serafini MS, Perrone F, Galbiati D, Sponghini AP, Depenni R, Vingiani A, Quattrone P, Marchesi E, Iannó MF, Micali A, Mancinelli E, Orlandi E, Marceglia S, Locati LD, Licitra L, Bossi…

Αλέξανδρος Γ. Σφακιανάκης

10:51

H&N
AA pubmed: head and neckCollaborative Multi-Disciplinary Incident Command at Seattle Children’s Hospital for Rapid Preparatory Pediatric Surgery Countermeasures to the COVID-19 Pandemic.Related ArticlesCollaborative Multi-Disciplinary Incident Command at Seattle Children’s Hospital for Rapid Preparatory Pediatric Surgery Countermeasures to the COVID-19 Pandemic. J Am Coll Surg. 2020 Apr 11;: Authors: Parikh SR, Avansino JR, Dick AA, Enriquez BK, Geiduschek JM, Martin LD, McDonald RA, Yandow SM,…

Αλέξανδρος Γ. Σφακιανάκης

10:50

MD
pubmed: sleepAntipsychotic agents deteriorate brain and retinal function in schizophrenia patients with combined auditory and visual hallucinations: A pilot study and secondary follow-up study.Related ArticlesAntipsychotic agents deteriorate brain and retinal function in schizophrenia patients with combined auditory and visual hallucinations: A pilot study and secondary follow-up study. Brain Behav. 2020 Apr 14;:e01611 Authors: Zhuo C, Xiao B, Chen C, Jiang D, Li G, Ma X, Li R, Wang L, Xu Y, Zhou…

Αλέξανδρος Γ. Σφακιανάκης

10:50

MED
pubmed: philosophy for medic…Antibiotic resistance as a tragedy of the commons: An ethical argument for a tax on antibiotic use in humans.Related ArticlesAntibiotic resistance as a tragedy of the commons: An ethical argument for a tax on antibiotic use in humans. Bioethics. 2019 09;33(7):776-784 Authors: Giubilini A Abstract To the extent that antibiotic resistance (ABR) is accelerated by antibiotic consumption and that it represents a serious public health emergency, it is imperative to drastically…

Αλέξανδρος Γ. Σφακιανάκης

10:49

MD
Latest Results for Cell and Tissue BankingEstablishment of a dynamic osteosarcoma biobank: Ruijin experienceAbstract Outcomes for patients with metastatic and recurrent osteosarcoma remain poor and a better understanding of the biology of this malignancy is critical to the development of prognostic biomarkers and novel therapies. The purpose of this study was to establish a biobank of osteosarcoma which has the potential of monitoring tumors dynamically with exosomes, to facilitate clinical and…

Αλέξανδρος Γ. Σφακιανάκης

10:47

Aerodynamic impact of total inferior turbinectomy versus inferior turbinoplasty – a computational fluid dynamics study.
Aerodynamic impact of total inferior turbinectomy versus inferior turbinoplasty – a computational fluid dynamics study.: Related ArticlesAerodynamic impact of total inferior turbinectomy versus inferior turbinoplasty – a computational fluid dynamics study.Rhinology. 2020 Apr 14;:Authors: Siu J, Inthavong K, Shang Y, Vahaji S, Douglas RGAbstract BACKGROUND: The aim of this study was to investigate using computational fluid dynamics (CFD) the effects on nasal aerodynamics of two different…

Αλέξανδρος Γ. Σφακιανάκης

10:47

Regression of Papillary Thyroid Cancer during Nivolumab for Renal Cell Cancer
Regression of Papillary Thyroid Cancer during Nivolumab for Renal Cell Cancer: Immune checkpoint inhibitors have been recently approved for cancer treatment. Nivolumab is a monoclonal antibody specific for programmed cell death-1 (PD-1) that modulates T-cell response. It was initially used for the treatment of malignant melanoma and then approved in other cancers, such as non-small cell lung cancer and clear cell renal cell carcinoma (ccRCC). So far, the activity of nivolumab in patients with thyroid…

Αλέξανδρος Γ. Σφακιανάκης

10:46

"Otolaryngol Head Neck Surg"[jour]; +18 new citations
"Otolaryngol Head Neck Surg"[jour]; +18 new citations: 18 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Otolaryngol Head Neck Surg"[jour]These pubmed results were generated on 2020/04/15PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.1.Otolaryngol…

Αλέξανδρος Γ. Σφακιανάκης

10:42

MEDIC
Latest Results for Archives of Toxicology25C-NBF, a new psychoactive substance, has addictive and neurotoxic potential in rodentsAbstract The use of new psychoactive substances (NPSs) as a substitute for illegal drugs is increasing rapidly and is a serious threat to public health. 25C-NBF is a newly synthesized phenethylamine-type NPS that acts as a 5-hydroxyindoleacetic acid (5-HT) receptor agonist, but little is known about its pharmacological effects. Considering that NPSs have caused unexpected…

Αλέξανδρος Γ. Σφακιανάκης

10:41

MD
Latest Results for Human StudiesTurning Points on the Path to a Phenomenological SociologyLatest Results for Human Studies16hMark above section as read ScienceDirect Publication: International Journal of Biological MacromoleculesEncapsulation and release characteristics of ethylene gas from V₆- and V₇-type crystalline starchesPublication date: 1 August 2020Source: International Journal of Biological Macromolecules, Volume 156Author(s): Linfan Shi, Li…

Αλέξανδρος Γ. Σφακιανάκης

10:40

MD
Endoscopic Ultrasound : 2014 – 3(1)Clinical and morphological consequences of permanent indwelling transmural plastic stents in disconnected pancreatic duct syndromeSurinder Singh Rana, Jimil Shah, Ravi K Sharma, Rajesh GuptaEndoscopic Ultrasound 2020 9(2):130-137 Background: Long-term indwelling transmural stents in patients with walled-off necrosis (WON) and disconnected pancreatic duct syndrome (DPDS) is an effective strategy to decrease risk of recurrence of pancreatic fluid collection (PFC)….

Αλέξανδρος Γ. Σφακιανάκης

10:39

MED
PLOS Pathogens: New ArticlesBaloxavir treatment of ferrets infected with influenza A(H1N1)pdm09 virus reduces onward transmissionby Leo Yi Yang Lee, Jie Zhou, Rebecca Frise, Daniel H. Goldhill, Paulina Koszalka, Edin J. Mifsud, Kaoru Baba, Takahiro Noda, Yoshinori Ando, Kenji Sato, Aoe-Ishikawa Yuki, Takao Shishido, Takeki Uehara, Steffen Wildum, Elke Zwanziger, Neil Collinson, Klaus Kuhlbusch, Barry Clinch, Aeron C. Hurt, Wendy S. Barclay Influenza viruses cause seasonal outbreaks and pose a continuous…

Αλέξανδρος Γ. Σφακιανάκης

10:38

Malignant transformation of a dysembryoplastic neuroepithelial tumor verified by a shared copy number gain of the tyrosine kinase domain of FGFR1
Malignant transformation of a dysembryoplastic neuroepithelial tumor verified by a shared copy number gain of the tyrosine kinase domain of FGFR1: AbstractDysembryoplastic neuroepithelial tumors (DNTs) are regarded as benign glioneuronal neoplasms because of their excellent outcomes; however, rare DNTs show malignant transformation. We herein described a case of DNT showing malignant transformation. The patient had intractable epilepsy caused by a tumor at 1 year of age and partial resection was…

Αλέξανδρος Γ. Σφακιανάκης

10:35

MD
Latest Results for European Journal of PediatricsThe effect of facilitated tucking position during painful procedure in pain management of preterm infants in neonatal intensive care unit: a systematic review and meta-analysisAbstract We performed a systematic review and meta-analysis to investigate the effects of facilitated tucking position during painful procedure in pain management of preterm infants. We searched MEDLINE, PEDro, SciELO and the Cochrane Library (until June 2019) for randomized…

Αλέξανδρος Γ. Σφακιανάκης

10:35

High flow nasal cannula as respiratory support in treating infant bronchiolitis: a systematic review
High flow nasal cannula as respiratory support in treating infant bronchiolitis: a systematic review: AbstractBronchiolitis is a common respiratory illness in early childhood, often leading to hospitalization and associated healthcare costs. Low flow 100% oxygen through nasal prongs is the standard therapy for infants with bronchiolitis and hypoxemia. Nasal continuous positive airway pressure (nCPAP) or invasive ventilation is used in case of progressive respiratory failure. High flow heated and…

Αλέξανδρος Γ. Σφακιανάκης

10:34

Arum palaestinum poisoning: revenge of the witch
Arum palaestinum poisoning: revenge of the witch: AbstractThe Arum palaestinum plant is one of the 26 species of the Arum genus of the Araceae family. This plant species is found through the Mediterranean region, Western Asia, and Europe. The leaves and seeds of the plant contain needle-shaped oxalate crystals that can irritate the affected tissue (skin, oral cavity, or GI tract) upon exposure. Up to this date, there is no available literature supporting the epidemiology or the clinical manifestations…

Αλέξανδρος Γ. Σφακιανάκης

10:33

PLOS Genetics
: New ArticlesAn integrated analysis of cell-type specific gene expression reveals genes regulated by REVOLUTA and KANADI1 in the Arabidopsis shoot apical meristemby Hasthi Ram, Sudeep Sahadevan, Nittaya Gale, Monica Pia Caggiano, Xiulian Yu, Carolyn Ohno, Marcus G. Heisler In the Arabidopsis thaliana shoot apical meristem (SAM) the expression domains of Class III Homeodomain Leucine Zipper (HD-ZIPIII) and KANADI (KAN) genes are separated by a narrow boundary region from which new organs are initiated….

Αλέξανδρος Γ. Σφακιανάκης

10:31

Aesthetic Plastic Surgery
Latest Results for Severe Challenges for Breast Reconstruction After Mastectomy in ChinaLatest Results for Aesthetic Plastic Surgery11hThe Importance of Nipple–Areola Complex Position in Chest Masculinization SurgeryLatest Results for Aesthetic Plastic Surgery11hBleeding in Plastic–Aesthetic Surgery: A Prognostic Pathway with Clinical ApplicationLatest Results for Aesthetic Plastic Surgery11hMark above section as read

Αλέξανδρος Γ. Σφακιανάκης

10:30

Abdominal Imaging
Latest Results for Imaging features, complications and differential diagnoses of abdominal cystic lymphangiomasAbstract Purpose The aim of the study is to describe the imaging features, complications and differential diagnoses of abdominal cystic lymphangiomas (ACLs). Results ACLs are benign lymphatic malformations that mainly arise in the subperitoneal space and the retroperitoneum. The typical presentation of an ACL is a multilocular lesion with homogenous serous…Latest Results for Abdominal…

Αλέξανδρος Γ. Σφακιανάκης

10:30

Advances in Therapy
Use of Dexmedetomidine in Transfemoral Transcatheter Aortic Valve Implantation (tf-TAVI) ProceduresAbstract Introduction Dexmedetomidine is a highly selective alpha-2 adrenoreceptor agonist without any effect on the GABA receptor. Its sedative, anxiolytic, analgesic, and sympatholytic activities together with opioid-sparing effects make it suitable for short- and long-term sedation in the intensive care setting. We report our experience with dexmedetomidine use during transfemoral transcatheter…

Αλέξανδρος Γ. Σφακιανάκης

10:29

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
Characterization of Gut Microbiota in Hospitalized Patients with Clostridioides difficile InfectionAbstract Clostridioides difficile infection (CDI) is one of the most common causes of nosocomial diarrhea in developed countries and the main cause in healthcare settings. This case–control study was designed to evaluate the composition of the gut microbiota dominant bacterial groups in patients with CDI compared to the healthy control subjects. A total of 100 adult subjects involving 50 inpatients…

Αλέξανδρος Γ. Σφακιανάκης

10:28

Plastic, Reconstructive & Aesthetic Surgery
Journal of Global Initiative for Children’s Surgery (GICS) – A Welcomed Step Towards Sustainable Global Paediatric Plastic SurgeryThe Global Initiative for Children’s Surgery (GICS) was established in 2016 to advance the access and quality of safe surgical and anaesthesia care for children in resource-limited settings.1 GICS is a global consortium of providers, institutions and organizations. Over half of its members originate from low and low-middle income countries (LMICs) and span multiple paediatric…

Αλέξανδρος Γ. Σφακιανάκης

10:28

Treatment of severe cutaneous adverse reaction with tocilizumab
Treatment of severe cutaneous adverse reaction with tocilizumab: AbstractA 29‐year‐old Chinese male with recurrent alveolar soft part sarcoma of the tongue metastatic to lung presented with fever and rash (Figure 1a). He underwent glossectomy and adjuvant radiotherapy, complicated by recurrence and abscess with sinus tract formation on the right neck. Current therapy included ipilimumab 3mg/kg and nivolumab 1mg/kg (completed 9 cycles; last dose two days before admission), and cabozantinib 40mg daily…

Αλέξανδρος Γ. Σφακιανάκης

10:26

Severe pyrexia from nivolumab‐resistant advanced melanoma after successful combined therapy with encorafenib plus binimetinib
Severe pyrexia from nivolumab‐resistant advanced melanoma after successful combined therapy with encorafenib plus binimetinib: AbstractVarious serious adverse events (AE) have been reported to occur at a high rate in patients treated with BRAF plus mitogen‐activated protein kinase kinase (MEK) inhibitor combination therapy, but their subtypes differ among the BRAF/MEK inhibitors. Pyrexia or a spike of fever are well‐known AE of BRAF inhibitors, with or without MEK inhibitors, and have been reported…

Αλέξανδρος Γ. Σφακιανάκης

10:25

MEDI
AuntMinnieEurope.com HeadlinesHard truths from COVID-19 front line in ParisWhat’s it really like working in a dedicated COVID-19 imaging facility? Radiologist…Read more on AuntMinnieEurope.comRelated Reading: Germany issues advice on use of CT in COVID-19 French expert offers 6 imaging tips to defeat COVID-19 Parma team shares experiences of COVID-19 pandemic Achenbach insists CT has role in COVID-19 cases VIDI joins forces with French public hospitals to deliver imagingAuntMinnieEurope.com HeadlinesnowRCR…

Αλέξανδρος Γ. Σφακιανάκης

10:25

Strategy to reduce unnecessary surgeries in thyroid nodules with cytology of Bethesda category III (AUS/FLUS): a retrospective analysis of 667 patients diagnosed by surgery
Strategy to reduce unnecessary surgeries in thyroid nodules with cytology of Bethesda category III (AUS/FLUS): a retrospective analysis of 667 patients diagnosed by surgery: AbstractPurposeFine-needle aspiration (FNA) is widely used for the diagnosis of thyroid nodules detected by ultrasonography. However, the cytology of atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) often leads to unnecessary thyroid surgery. This study aimed to identify a strategy…

Αλέξανδρος Γ. Σφακιανάκης

10:23

MD
PsychophysiologyThe Maryland analysis of developmental EEG (MADE) pipelineAbstract Compared to adult EEG, EEG signals recorded from pediatric populations have shorter recording periods and contain more artifact contamination. Therefore, pediatric EEG data necessitate specific preprocessing approaches in order to remove environmental noise and physiological artifacts without losing large amounts of data. However, there is presently a scarcity of standard automated preprocessing pipelines suitable…

Αλέξανδρος Γ. Σφακιανάκης

10:22

MED
International Journal of NanomedicineGreen Synthesis, Characterization and Antimicrobial Activity of Copper Oxide Nanomaterial Derived from Momordica charantiaInternational Journal of Nanomedicine6hMark above section as read NEN : Last 20 articlesPharmacological acromegaly treatment: cost-utility and value of information analysisObjectives: To conduct a cost-utility analysis comparing drug strategies involving octreotide, lanreotide, pasireotide, and pegvisomant for the treatment of patients with…

Αλέξανδρος Γ. Σφακιανάκης

10:21

MD
Hindawi Publishing CorporationConductivity, Surface Tension, and Comparative Antibacterial Efficacy Study of Different Brands of Soaps of NepalThe current study aims to evaluate the solution properties and antibacterial efficacy study of five different brands of toilet soaps of Nepal such as Okhati (OKT), Lifebuoy (LFBY), Lux (LX), Liril (LRL), and Chiuree Neem (NM). The evaluation of critical micelle concentration (CMC) and their thermodynamics and surface properties are also reported. This study…

Αλέξανδρος Γ. Σφακιανάκης

10:21

Stevens–Johnson Syndrome and Herpes Simplex Type 1 Infection during Adalimumab Therapy for Crohn’s Disease
Stevens–Johnson Syndrome and Herpes Simplex Type 1 Infection during Adalimumab Therapy for Crohn’s Disease: Stevens–Johnson syndrome (SJS) is a severe mucocutaneous adverse drug reaction with a relatively high mortality rate. SJS is described during herpes simplex virus type 1 (HSV1) infection and, rarely, even during adalimumab therapy. We report the case of a patient with Crohn’s disease who developed SJS during an HSV1 infection and a contemporaneous anti-TNFα therapy with adalimumab. Remission…

Αλέξανδρος Γ. Σφακιανάκης

10:20

MED
Hindawi Publishing CorporationPrevalence of Neonatal Sepsis in Ethiopia: A Systematic Review and Meta-AnalysisIntroduction. Neonatal sepsis is a systemic infection occurring in infants during the first 4 weeks of life and is a major cause of mortality and morbidities of newborns due to their age-related weak and immature immune systems. In Ethiopia, despite many studies being conducted on neonatal sepsis, the reported findings are inconsistent. The aim of this study is to determine the prevalence…

Αλέξανδρος Γ. Σφακιανάκης

10:18

MD
NIM : Last 20 articlesPolyinosinic-Polycytidylic Acid Induces CXCL1 Expression in Cultured hCMEC/D3 Human Cerebral Microvascular Endothelial CellsObjective: Brain microvascular endothelial cells are integral components of the blood-brain barrier and play a role in protecting the brain from invading microbes. CXC motif chemokine ligand 1 (CXCL1) induces the chemotaxis of neutrophils, and neutrophils are important in host defense in the brain. However, dysregulated neutrophil infiltration leads to…

Αλέξανδρος Γ. Σφακιανάκης

10:17

Effect of Auditory Predictability on the Human Peripheral Auditory System
https://www.frontiersin.org/articles/10.3389/fnins.2020.00362/pdffnins-14-00362 April 10, 2020 Time: 17:59 # 1ORIGINAL RESEARCHpublished: 15 April 2020doi: 10.3389/fnins.2020.00362Edited by:Jonathan B. Fritz,New York University, United StatesReviewed by:Paul Hinckley Delano,University of Chile, ChileJaakko Kauramäki,University of Helsinki, FinlandJohn J. Guinan,Massachusetts Eye & Ear Infirmaryand Harvard Medical School,United States*Correspondence:Lars Rieckel.riecke@maastrichtuniversity.nlSpecialty…

Αλέξανδρος Γ. Σφακιανάκης

10:15

MED
Latest Results for European Archives of Oto-Rhino-LaryngologySwallow-related quality of life and oropharyngeal dysphagia in myotonic dystrophyAbstract Purpose This study describes swallow-related quality of life (SWAL-QOL) in patients with myotonic dystrophy type 1 (DM1) and investigates its association with swallowing function and disease severity. Methods A SWAL-QOL questionnaire was completed by 75 DM1 patients and 25 healthy control subjects. The severity of the disease was evaluated using…Latest…

Αλέξανδρος Γ. Σφακιανάκης

10:14

MED
BMJ Case Reports Last 6 IssuesMultimodal imaging-guided diagnosis, management and follow-up of a case of diffuse unilateral subacute neuroretinitisA 45-year-old woman presented with diminished vision in the left eye. Visual acuity was 6/9 and fundus showed a very large live nematode near the macula along with inflammatory outer retinal lesions in the periphery. We diagnosed the case as diffuse unilateral subacute neuroretinitis and treated with immediate focal photocoagulation of the worm along…

Αλέξανδρος Γ. Σφακιανάκης

10:11

Case of neuromyelitis optica: bilateral sensorineural hearing loss and transverse myelopathy following intrathecal chemotherapy 1hby Castillo-Torres, S. A., Soto-Rincon, C. A., Villarreal-Montemayor, H. J., Chavez-Luevanos, B. via BMJ Case Reports Last 6 Issues Neurotoxicity from intrathecally administered chemotherapeutic drugs is frequent, particularly with some agents like methotrexate, which are more prone to developing adverse effects. Myelopathy ranks among the most frequently reported neurological entities; with the diagnosis being straightforward, after ruling out infectious, metabolic, autoimmune or paraneoplastic causes. Scarcity of cases precludes evidence-based recommendations for the management of these complications. The most common therapeutic approach consists of the suspension of chemotherapy, exclusion of infectious and neoplastic causes, with prompt administration of high-dose steroids. We report a 21-year-old patient with acute lymphoblastic leukaemia, who developed acute transverse myelitis and bilateral sensorineural hearing loss, after five rounds of intrathecal methotrexate and cytarabine. Although neurotoxicity from both agents has been documented, this combination has not been previously reported.

Αλέξανδρος Γ. Σφακιανάκης

10:09

Dramatic recovery of vision in patient with acute central retinal artery occlusion treated with local intra-arterial tissue plasminogen activator 1hby Margolin, E. A., Rai, A., Goldfarb, J., Zaslavsky, K., Kohly, R., Nicholson, P. via BMJ Case Reports Last 6 Issues Central retinal artery occlusion (CRAO) is a devastating disease resulting in severe visual loss in most cases. It has no proven treatment, and a variety of management options used clinically all have dismal rate of success. We report outcome of treatment with local intra-arterial thrombolysis administered 2.75 hours after devastating visual loss from incomplete CRAO.

Αλέξανδρος Γ. Σφακιανάκης

10:08

MD
Latest Results for Cancer Immunology, ImmunotherapyCharacterization of an HLA-restricted and human cytomegalovirus-specific antibody repertoire with therapeutic potentialAbstract With an infection rate of 60–90%, the human cytomegalovirus (HCMV) is very common among adults but normally causes no symptoms. When T cell-mediated immunity is compromised, HCMV reactivation can lead to increased morbidity and mortality. HCMV antigens are processed and presented as peptides on the cell surface via HLA…

Αλέξανδρος Γ. Σφακιανάκης

10:07

Remove ads


MED
Latest Results for Der ChirurgNeoadjuvante und adjuvante Therapie beim PankreaskarzinomZusammenfassung Hintergrund Die Resektion ist die einzige kurative Therapieoption beim Pankreaskarzinom. Adjuvante Chemotherapie kann das krankheitsfreie Überleben und Gesamtüberleben nach Resektion verbessern. Zurzeit werden darüber hinaus neoadjuvante Konzepte in zahlreichen Studien untersucht. Ziel der Arbeit Zusammenfassung der aktuellen Datenlage bezüglich…Latest Results for Der Chirurg8mDie nekrotisierende…

Αλέξανδρος Γ. Σφακιανάκης

10:06

Obesity Reviews
Physical activity interventions promoted in the Arabic‐speaking region: A review of the current literatureSummary The Arabic‐speaking region suffers from insufficient levels of physical activity (PA). Assessing the effectiveness of PA interventions presents a scientifically evaluated method to reduce and prevent the current high burden of noncommunicable diseases affecting this region. This review examined implemented PA interventions and corresponding measured health outcomes in this region. The…

Αλέξανδρος Γ. Σφακιανάκης

10:05

MDPI Journals
NutrientsNutrients, Vol. 12, Pages 1092: Large Neutral Amino Acids (LNAAs) Supplementation Improves Neuropsychological Performances in Adult Patients with PhenylketonuriaNutrients, Vol. 12, Pages 1092: Large Neutral Amino Acids (LNAAs) Supplementation Improves Neuropsychological Performances in Adult Patients with Phenylketonuria Nutrients doi: 10.3390/nu12041092 Authors: Iris Scala Maria Pia Riccio Maria Marino Carmela Bravaccio Giancarlo Parenti Pietro Strisciuglio Phenylketonuria is an inborn…

Αλέξανδρος Γ. Σφακιανάκης

10:02

MDPI Journals
VaccinesVaccines, Vol. 8, Pages 187: Disruption of the cpsE and endA Genes Attenuates Streptococcus pneumoniae Virulence: Towards the Development of a Live Attenuated Vaccine CandidateVaccines, Vol. 8, Pages 187: Disruption of the cpsE and endA Genes Attenuates Streptococcus pneumoniae Virulence: Towards the Development of a Live Attenuated Vaccine Candidate Vaccines doi: 10.3390/vaccines8020187 Authors: Malik Amonov Nordin Simbak Wan Mohd. Razin Wan Hassan Salwani Ismail Nor Iza A. Rahman Stuart…

Αλέξανδρος Γ. Σφακιανάκης

10:03

MDPI Journals
MicroorganismsMicroorganisms, Vol. 8, Pages 573: The Controversial Role of Human Gut LachnospiraceaeMicroorganisms, Vol. 8, Pages 573: The Controversial Role of Human Gut Lachnospiraceae Microorganisms doi: 10.3390/microorganisms8040573 Authors: Mirco Vacca Giuseppe Celano Francesco Maria Calabrese Piero Portincasa Marco Gobbetti Maria De Angelis The complex polymicrobial composition of human gut microbiota plays a key role in health and disease. Lachnospiraceae belong to the core of gut microbiota,…

Αλέξανδρος Γ. Σφακιανάκης

10:01

MDPI Journals
International Journal of Molecular SciencesIJMS, Vol. 21, Pages 2742: Molecular Mechanisms, Diagnostic Aspects and Therapeutic Opportunities of Micro Ribonucleic Acids in Atrial FibrillationIJMS, Vol. 21, Pages 2742: Molecular Mechanisms, Diagnostic Aspects and Therapeutic Opportunities of Micro Ribonucleic Acids in Atrial Fibrillation International Journal of Molecular Sciences doi: 10.3390/ijms21082742 Authors: Allan Böhm Marianna Vachalcova Peter Snopek Ljuba Bacharova Dominika Komarova Robert…

Αλέξανδρος Γ. Σφακιανάκης

10:01

MDPI Journals
International Journal of Environmental Research and Public HealthIJERPH, Vol. 17, Pages 2715: Competitive Growth of Sulfate-Reducing Bacteria with Bioleaching Acidophiles for Bioremediation of Heap Bioleaching ResidueIJERPH, Vol. 17, Pages 2715: Competitive Growth of Sulfate-Reducing Bacteria with Bioleaching Acidophiles for Bioremediation of Heap Bioleaching Residue International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082715 Authors: Aung Kyaw Phyo Yan Jia Qiaoyi…

Αλέξανδρος Γ. Σφακιανάκης

10:00

MDPI Journals
CellsCells, Vol. 9, Pages 982: Necroptosis in CholangiocarcinomaCells, Vol. 9, Pages 982: Necroptosis in Cholangiocarcinoma Cells doi: 10.3390/cells9040982 Authors: Samantha Sarcognato Iris E. M. de Jong Luca Fabris Massimiliano Cadamuro Maria Guido Necroptosis is a type of regulated cell death that is increasingly being recognized as a relevant pathway in different pathological conditions. Necroptosis can occur in response to multiple stimuli, is triggered by the activation of death receptors,…

Αλέξανδρος Γ. Σφακιανάκης

09:59

MDPI Journals
Antibiotics, Vol. 9, Pages 183: Evaluation of Oxytetracycline Metabolites Cross-Reactivity with Oxytetracycline Enzyme-Linked Immunosorbent Assay (ELISA)Antibiotics, Vol. 9, Pages 183: Evaluation of Oxytetracycline Metabolites Cross-Reactivity with Oxytetracycline Enzyme-Linked Immunosorbent Assay (ELISA) Antibiotics doi: 10.3390/antibiotics9040183 Authors: Faraj Hijaz Nabil Killiny Antibiotics have been successfully used for the control of several plant diseases for many years. Recently, streptomycin…

Αλέξανδρος Γ. Σφακιανάκης

09:58

Mark above section as read

#
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia,

Telephone consultation 11855 int 1193,

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com, Telephone consultation 11855 int 1193,

Medicine
Journal of AnatomyOntogeny and homology of cranial bones associated with lateral‐line canals of the Senegal Bichir, Polypterus senegalus (Actinopterygii: Cladistii: Polypteriformes), with a discussion on the formation of lateral‐line canal bones in fishesWe describe the development of bones associated with lateral‐line canals in the Senegal Bichir and use these data to re‐address previous hypotheses of homology of skull bones of polypterids. We demonstrate that the lateral‐line canals comprise a…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:28

COVID‐19 indirect contact transmission through the oral mucosa must not be ignored
COVID‐19 indirect contact transmission through the oral mucosa must not be ignored: AbstractBackgroundCoronavirus (CoV) is the single stranded sense RNA virus that has been known so far with the largest genomic capacity and plenty of natural hosts. In the past dozens of years, SARS‐CoV under the branch of the new evolutionary tree has threatens greatly global public health and the severe acute respiratory syndrome new coronavirus (COVID‐19) reported in China could cause fatal pathological lesions….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:27

Value of colchicine as treatment for recurrent oral ulcers: a systematic review
Value of colchicine as treatment for recurrent oral ulcers: a systematic review: AbstractBackgroundin oral medicine, colchicine is a therapeutic alternative for idiopathic recurrent aphthous stomatitis (RAS), Behçet disease (BD), Periodic Fever, Aphthous stomatitis, Pharyngitis, and cervical Adenitis (PFAPA) syndrome, and Mouth and Genitals Ulcers with Inflamed Cartilage (MAGIC) syndrome. The present review aims to evaluate reliability of colchicine against recurrent oral ulcers.MethodsA systematic…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:27

Cancer Medicine
Association between cancer‐specific adverse event triggers and mortality: A validation studyIn a retrospective longitudinal cohort of 322 887 newly diagnosed patients with breast, colorectal, lung, or prostate cancer, there was increased one‐year mortality among patients who experienced oncology‐specific claims‐based triggers compared to patients without triggers. Increased mortality was observed across all cancer types, stratified by metastatic status, in unadjusted and multivariate analyses. Abstract…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:26

Allergy & Rhinology
Olfactory dysfunction from acute upper respiratory infections: relationship to season of onsetBackground Acute viral upper respiratory tract infections are the most common cause of chronic olfactory dysfunction. In light of the seasonality of numerous viruses, the question arises as to whether the frequency and magnitude of postviral olfactory disorders (PVODs) are similarly seasonal. We sought to determine whether olfactory deficits due to influenza and non–influenza‐related viruses (I‐PVODs and…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:26

Dermatology
Australasian Journal of DermatologyAngiolymphoid hyperplasia with eosinophilia of the tongue with a Sézary syndrome history: Evidence for immune mediation of the diseaseAustralasian Journal of Dermatology22hProfound pearly penile papulesAustralasian Journal of Dermatology22hTildrakizumab in the treatment of PASH syndrome: A potential novel therapeutic targetAustralasian Journal of Dermatology22hKeratinocyte cancer with incidental perineural invasion: A registry analysis of management and 5‐year…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:25

Oral and Maxillofacial Surgery
Latest Results for Oral and Maxillofacial SurgeryFull-staged digital and prosthetic guided protocol for the insertion of dental implants in autogenous free bone grafts after reconstruction of segmental mandibular defectsAbstract Purpose This study aims to evaluate the clinical and radiographic outcomes of dental implants, inserted in consolidated free bone grafts; postsegmental mandibular resection, after following a fully guided staged protocol, which established a systematic approach that correlates…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:25

Exploding head syndrome, chronotype, parasomnias and mental health in young adults
Exploding head syndrome, chronotype, parasomnias and mental health in young adults: AbstractAlthough inadequate sleep among young people is well documented in the literature, anomalous sleep experiences, such as the parasomnia termed exploding head syndrome (EHS), have received little empirical attention. The current study examined the association of sleep quality, symptoms of psychological distress and other unusual sleep experiences with EHS in a sample of young adults (n = 135, age M = 21.77,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:24

Modulation of Airway Epithelial Innate Immunity and Wound Repair by M(GM-CSF) and M(M-CSF) Macrophages
Modulation of Airway Epithelial Innate Immunity and Wound Repair by M(GM-CSF) and M(M-CSF) Macrophages: Airway epithelial cells and macrophages participate in inflammatory responses to external noxious stimuli, which can cause epithelial injury. Upon injury, epithelial cells and macrophages act in concert to ensure rapid restoration of epithelial integrity. The nature of the interactions between these cell types during epithelial repair is incompletely understood. We used an in vitro human coculture…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:23

Bone Marrow Langerhans Cell Histiocytosis in Association with Kasabach-Merritt Syndrome: The Difficulty of a Differential Diagnosis
Bone Marrow Langerhans Cell Histiocytosis in Association with Kasabach-Merritt Syndrome: The Difficulty of a Differential Diagnosis: Langerhans cell histiocytosis is a rare haematological disorder with variable clinical findings and a high mortality rate. On the other hand, Kasabach-Merritt syndrome is of rare onset at adult age, requiring the simultaneous presentation of vascular lesion, thrombocytopenia, and consumptive coagulopathy. We present the first reported case of both diseases in a single…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:23

Sleep
pubmed: sleepStudy of knowledge, attitude, anxiety & perceived mental healthcare need in Indian population during COVID-19 pandemic.Related ArticlesStudy of knowledge, attitude, anxiety & perceived mental healthcare need in Indian population during COVID-19 pandemic. Asian J Psychiatr. 2020 Apr 08;51:102083 Authors: Roy D, Tripathy S, Kar SK, Sharma N, Verma SK, Kaushal V Abstract Novel Corona Virus Disease (COVID-19) originating from China has rapidly crossed borders, infecting people throughout…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:22

The rs11187533 C>T Variant of the FFAR4 Gene Is Associated with Lower Levels of Fasting Glucose and Decreases in Markers of Liver Injury in Children with Obesity
The rs11187533 C>T Variant of the <b><i>FFAR4</i></b> Gene Is Associated with Lower Levels of Fasting Glucose and Decreases in Markers of Liver Injury in Children with Obesity: Introduction: Genetic factors can modulate the development of associated comorbidities in obesity. It has been shown that loss-of-function variants of the free fatty acid receptor 4 (FFAR4) gene negatively affect obesity comorbidities such as insulin resistance and fatty liver disease. Objective:…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

10:20

Integrative Medicine
Latest Results for Chinese Journal of Integrative MedicineMAO Ze-dong’s View on Traditional Chinese Medicine and Its Modern SignificanceAbstract MAO Ze-dong’s view on traditional Chinese medicine (TCM) can be divided into the scientific view on TCM, the development view on TCM and the future view on TCM. The core of MAO Ze-dong’s view on TCM lies in its scientific nature. The basic content of MAO Ze-dong’s development view on TCM includes unity of TCM and Western medicine (WM), advocating the multi-angle…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:45

Angiolymphoid hyperplasia with eosinophilia of the tongue with a Sézary syndrome history: Evidence for immune mediation of the disease.
Angiolymphoid hyperplasia with eosinophilia of the tongue with a Sézary syndrome history: Evidence for immune mediation of the disease.: Related ArticlesAngiolymphoid hyperplasia with eosinophilia of the tongue with a Sézary syndrome history: Evidence for immune mediation of the disease.Australas J Dermatol. 2020 Apr 13;:Authors: Lin SF, Wei YM, Fan Y, Sun CFPMID: 32281101 [PubMed – as supplied by publisher]

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:44

Microcystic Adnexal Carcinoma of the Face Treated With Definitive Chemoradiation: A Case Report and Review of the Literature.
Microcystic Adnexal Carcinoma of the Face Treated With Definitive Chemoradiation: A Case Report and Review of the Literature.: Microcystic adnexal carcinoma (MAC) is a rare, malignant appendage tumor commonly classified as a low-grade sweat gland carcinoma that typically occurs on the head and neck, particularly the central face. Microcystic adnexal carcinoma shows aggressive local invasion with rare reports of lymph node metastases.Feb 20, 2019Microcystic Adnexal Carcinoma: Practice Essentials …Related…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:43

Verrucous hyperplasia and verrucous carcinoma in head and neck: use and benefit of methotrexate.
Verrucous hyperplasia and verrucous carcinoma in head and neck: use and benefit of methotrexate.: Related ArticlesVerrucous hyperplasia and verrucous carcinoma in head and neck: use and benefit of methotrexate.Acta Clin Belg. 2020 Apr 11;:1-5Authors: De Keukeleire S, De Meulenaere A, Deron P, Huvenne W, Fréderic D, Bouckenooghe O, Ferdinande L, Creytens D, Rottey SAbstract Background and aim: Verrucous hyperplasia (VH) and verrucous carcinoma (VC) of the head and neck are two (pre)malignant…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:41

An Unusual Case of Noisy Breathing in an Infant.
An Unusual Case of Noisy Breathing in an Infant.: Related ArticlesAn Unusual Case of Noisy Breathing in an Infant.J Clin Sleep Med. 2019 01 15;15(1):149-152Authors: Leon-Astudillo C, Lee GS, Katwa UAbstract ABSTRACT: Laryngomalacia is a common cause of chronic noisy breathing that can present as stridor in infants and neonates. Mild cases of laryngomalacia are usually followed clinically and managed conservatively. However, the evaluation and diagnosis could be challenging in some patients….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:39

The role of polysomnography in decannulation of children with brain and spinal cord injuries.
The role of polysomnography in decannulation of children with brain and spinal cord injuries.: Related ArticlesThe role of polysomnography in decannulation of children with brain and spinal cord injuries.Pediatr Pulmonol. 2019 03;54(3):333-341Authors: Morrow AK, Tunkel DE, Collaco JM, McGrath-Morrow SA, Lam JC, Accardo JA, Rybczynski SVAbstract OBJECTIVE: The objective of this retrospective review was to determine the utility of polysomnography (PSG) in influencing the decision to decannulate…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:39

Periodontitis is associated with incident chronic liver disease-A population-based cohort study.
Periodontitis is associated with incident chronic liver disease-A population-based cohort study.: Related ArticlesPeriodontitis is associated with incident chronic liver disease-A population-based cohort study.Liver Int. 2019 03;39(3):583-591Authors: Helenius-Hietala J, Suominen AL, Ruokonen H, Knuuttila M, Puukka P, Jula A, Meurman JH, Åberg FAbstract BACKGROUND & AIMS: Chronic liver disease is a major health concern worldwide and the identification of novel modifiable risk factors…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:38

head and neck
AA pubmed: head and neckGeneration of craniofacial myogenic progenitor cells from human induced pluripotent stem cells for skeletal muscle tissue regeneration.Related ArticlesGeneration of craniofacial myogenic progenitor cells from human induced pluripotent stem cells for skeletal muscle tissue regeneration. Biomaterials. 2020 Apr 02;248:119995 Authors: Kim E, Wu F, Wu X, Choo HJ Abstract Craniofacial skeletal muscle is composed of approximately 60 muscles, which have critical functions including…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:38

Bloody Diarrhea in a 17-year-old Male……infection with HIV-1
Bloody Diarrhea in a 17-year-old Male: A 17-year-old African American male presented to the emergency department complaining of 5 days of diarrhea, which was watery and intermittently bloody. He had engaged in his first act of condomless receptive anal intercourse 2 months prior. Additionally, he reported a diagnosis of “strep throat” 1 week before this presentation but did not receive antimicrobial treatment. Vital signs were within normal limits, and the patient was afebrile upon presentation,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:33

philosophy for medicine
pubmed: philosophy for medic…Condom use philosophy and behaviors among young men who have sex with men: Variations among HIV pre-exposure prophylaxis users and nonusers.Related ArticlesCondom use philosophy and behaviors among young men who have sex with men: Variations among HIV pre-exposure prophylaxis users and nonusers. J Am Assoc Nurse Pract. 2020 Apr 08;: Authors: Fontenot HB, Krakower D, White BP, Marquez SM, Dormitzer J, Psaros C, OʼCleirigh C, Mayer KH Abstract BACKGROUND: In the United…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:31

Preoperative Factors Associated with Extrathyroidal Extension in Papillary Thyroid Cancer…………….: Older age, a greater BMI, a larger tumor size, and presence of the BRAF mutation were predictive of extrathyroidal extension. These factors should be taken into consideration in decision-making before surgery is performed.
Preoperative Factors Associated with Extrathyroidal Extension in Papillary Thyroid Cancer: Objective: Extrathyroidal extension may not be accurately recognized during thyroidectomy and can increase the risk of positive margins and even recurrence. This study aimed to investigate the preoperative factors associated with extrathyroidal extension. Methods: We analyzed 887 patients with papillary thyroid cancer (PTC) who underwent surgery in the period of 2005–2017. Binary logistic regression analyses…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:28

Traditional Chinese Medicine
MAO Ze-dong’s View on Traditional Chinese Medicine and Its Modern SignificanceAbstract MAO Ze-dong’s view on traditional Chinese medicine (TCM) can be divided into the scientific view on TCM, the development view on TCM and the future view on TCM. The core of MAO Ze-dong’s view on TCM lies in its scientific nature. The basic content of MAO Ze-dong’s development view on TCM includes unity of TCM and Western medicine (WM), advocating the multi-angle development of TCM from the height of Chinese national…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:28

Vaccination of Mice with isteria ivanovii Expressing the Truncated M Protein of Porcine Reproductive and Respiratory Syndrome Virus Induces both Antigen-Specific CD4+ and CD8+ T Cell-Mediated Immunity
Vaccination of Mice with <b><i>Listeria ivanovii</i></b> Expressing the Truncated M Protein of Porcine Reproductive and Respiratory Syndrome Virus Induces both Antigen-Specific CD4+ and CD8+ T Cell-Mediated Immunity: Porcine reproductive and respiratory syndrome (PRRS), a serious disease of swine caused by the PRRS virus (PRRSV), had a severe economic impact worldwide. As commonly used PRRS vaccines, the attenuated or inactivated vaccines, provide unsatisfactory immune protection,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:27

Management of epistaxis in patients on novel oral anticoagulation therapy…………. Idarucizumab is an effective antidote for bleeding associated with dabigatran use.
Management of epistaxis in patients on novel oral anticoagulation therapy.: Related ArticlesManagement of epistaxis in patients on novel oral anticoagulation therapy.J Laryngol Otol. 2020 Apr 13;:1-7Authors: Ho JPK, Bari N, Riffat FAbstractBACKGROUND: Individuals on anticoagulation therapy are at increased risk of bleeding, including epistaxis. There is a lack of available reversal agents for novel oral anticoagulation therapy.OBJECTIVE: This paper reviews the current literature on epistaxis in…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:26

BRC
BRC : Last 10 articlesThe Usefulness of the Pretreatment Neutrophil/Lymphocyte Ratio as a Predictor of the 5-Year Survival in Stage 1–3 Triple Negative Breast Cancer PatientsBackground: We have previously shown that the neutrophil/lymphocyte ratio (NLR) is a predictor of survival among breast cancer patients. The aim of this study was to determine the predictive value of NLR among different nodal and chemotherapy subgroups of triple negative breast cancer (TNBC). Methods: Patients with stage 1–3…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:23

oral oncology
pubmed: "oral oncol"[jour]Induction versus adjuvant chemotherapy combined with concurrent chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma: A propensity score-matched analysis.Related ArticlesInduction versus adjuvant chemotherapy combined with concurrent chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma: A propensity score-matched analysis. Oral Oncol. 2020 Apr 10;105:104686 Authors: Tang SQ, Xu C, Wang XS, Tang LL, Li WF, Chen L, Mao YP, Guo R, Liu Q, Sun…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:23

Antibiotics
Antibiotics, Vol. 9, Pages 180: Polyphasic Validation of a Nisin-Biogel to Control Canine Periodontal DiseaseAntibiotics, Vol. 9, Pages 180: Polyphasic Validation of a Nisin-Biogel to Control Canine Periodontal Disease Antibiotics doi: 10.3390/antibiotics9040180 Authors: Cunha Freitas Braz Silva Tavares Veiga Oliveira Background: Periodontal disease (PD) is a highly prevalent inflammatory disease in dogs. This disease is initiated by a polymicrobial biofilm on the teeth surface, whose control includes…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:22

The Utility of Genetic Testing for Familial Hypercholesterolemia
JPM, Vol. 10, Pages 23: A Global Review on the Utility of Genetic Testing for Familial Hypercholesterolemia: JPM, Vol. 10, Pages 23: A Global Review on the Utility of Genetic Testing for Familial HypercholesterolemiaJournal of Personalized Medicine doi: 10.3390/jpm10020023Authors: Rachele M. Hendricks-Sturrup Jodi Clark-LoCascio Christine Y. Lu Familial hypercholesterolemia (FH) is a genetic disorder of cholesterol metabolism that affects an estimated 1/250 persons in the United States and…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:21

310 nm UV-LED Attenuates Imiquimod-Induced Psoriasis-like Skin Lesions in C57BL/6 Mice and Inhibits IL-22-Induced STAT3 Expression in HaCaT Cells
310 nm UV-LED Attenuates Imiquimod-Induced Psoriasis-like Skin Lesions in C57BL/6 Mice and Inhibits IL-22-Induced STAT3 Expression in HaCaT Cells: Photochem. Photobiol. Sci., 2020, Accepted ManuscriptDOI: 10.1039/C9PP00444K, PaperTae-Rin Kwon, Sung-Eun Lee, Jong-Hwan Kim, Yu Na Jang, Su-Young Kim, Seok Kyun Mun, Chan Woong Kim, Jungtae Na, Beom Joon KimUltraviolet light-emitting diodes (UV-LEDs) are a novel light source for phototherapy. This study aimed to evaluate the therapeutic effects of UV-LEDs…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:21

Cancer Research
Online First ArticlesGolgi-localized PAQR4 mediates Anti-apoptotic Ceramidase Activity in Breast CancerThe metabolic network of sphingolipids plays important roles in cancer biology. Prominent sphingolipids include ceramides and sphingosine-1-phosphate that regulate multiple aspects of growth, apoptosis, and cellular signaling. Although a significant number of enzymatic regulators of the sphingolipid pathway have been described in detail, many remained poorly characterized. Here we applied a patient-derived…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:20

Nonsurgical Treatments for Extramammary Paget Disease:: Imiquimod and radiotherapy are the most appropriate nonsurgical modalities for EMPD treatment given their good efficacy and safety profile. PDT has limited efficacy but may be appropriate in selected clinical settings.
Nonsurgical Treatments for Extramammary Paget Disease: A Systematic Review and Meta-Analysis: Introduction: Surgery is commonly regarded as the mainstay of treatment of extramammary Paget disease (EMPD); however, nonsurgical approaches have gained popularity in recent years. Objectives: To review the published evidence for the efficacy and safety of nonsurgical modes of therapy for EMPD. Methods: A systematic review and meta-analysis of nonsurgical EMPD treatments was performed. The primary outcome…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:19

20 σπάνια γυναίκεια ονόματα και η σημασία τους
20 σπάνια γυναίκεια ονόματα και η σημασία τους: Δεν έχετε καταλήξει ακόμα στο όνομα που θα δώσετε στο κοριτσάκι σας; Η παράδοση θέλει τα ονόματα να περνάνε από γενιά σε γενιά και από τον παππού και τη γιαγιά στα εγγόνια έχει υπάρχει ακόμα και στις μέρες μας. Αν όμως εσείς θέλετε να πρωτοτυπήσετε, μπορείτε να επιλέξετε κάποιο από τα πιο ασυνήθιστα ελληνικά ή […]1. Άλκηστις: η δύναμη του σπιτιού και της οικογένειας είναι η ακριβής σημασία του ονόματος -και όχι άδικα, αφού η κόρη σας είναι η ψυχή της…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:19

Der Chirurg
Latest Results for Der ChirurgMehr Hemithyroidektomien in den USA beim Schilddrüsenkarzinom nach Publikation der ATA-LeitlinienLatest Results for Der Chirurg15hTherapie kolorektaler und nichtkolorektaler Lebermetastasen: Sinnhaftigkeit neoadjuvanter TherapiekonzepteZusammenfassung Hintergrund Lebermetastasen stellen die häufigste sekundär maligne Erkrankung der Leber dar. Zahlen zur Inzidenz kolorektaler und nichtkolorektaler Lebermetastasen lassen sich aufgrund mangelnder Erfassung in Registern…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:15

Medical Internet Research
*Journal* of *Medical Internet Research*Internet Hospitals Help Prevent and Control the Epidemic of COVID-19 in China: Multicenter User Profiling Study*Journal* of *Medical Internet Research*15hThe Buffering Effect of Health Care Provider Video Biographies When Viewed in Combination With Negative Reviews: “You Can’t Fake Nice”*Journal* of *Medical Internet Research*15hExploring the Factors Influencing Consumers to Voluntarily Reward Free Health Service Contributors in Online Health Communities:…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:15

Explaining Parkinsonian Postural Sway Variabilities Using Intermittent Control Theory
Explaining Parkinsonian Postural Sway Variabilities Using Intermittent Control Theory: Publication date: Available online 13 April 2020Source: Journal of BiomechanicsAuthor(s): Ranjita Dash, Vrutangkumar V. Shah, Harish J. Palanthandalam-Madapusi

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:14

Gene
GeneRegulation of growth-related genes by nutrition in paralarvae of the common octopus (<em>Octopus vulgaris</em>)Publication date: Available online 13 April 2020Source: GeneAuthor(s): D. Garcia de la serrana, M. Pérez, M. Nande, J. Hernández-Urcera, E. Pérez, C. Coll-Lladó, C. HollenbeckGene14hMachine learning identifies 10 feature miRNAs for Lung squamous cell carcinomaPublication date: Available online 13 April 2020Source: GeneAuthor(s): Zheng Ye, Bo Sun, Zhongdang XiaoGene14hMark…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:14

Comparison of ATG-thymoglobulin with ATG-Fresenius for Epstein-Barr virus infections and graft-versus-host-disease in patients with hematological malignances after haploidentical hematopoietic stem cell transplantation: a single-center experience
Comparison of ATG-thymoglobulin with ATG-Fresenius for Epstein-Barr virus infections and graft-versus-host-disease in patients with hematological malignances after haploidentical hematopoietic stem cell transplantation: a single-center experience: AbstractTwo anti-thymocyte globulin (ATG) forms are used in graft-versus-host disease (GVHD) prophylaxis during haploidentical hematopoietic stem cell transplantations (haplo-HSCTs): ATG-thymoglobulin (ATG-T) and ATG-fresenious (ATG-F). However, comparable…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:13

Remove ads


Cancer Cell
ScienceDirect Publication: Changing for a Better FuturePublication date: 13 April 2020Source: Cancer Cell, Volume 37, Issue 4Author(s): Steve MaoScienceDirect Publication: Cancer Cell14hIntegrated Molecular and Clinical Analysis of 1,000 Pediatric Low-Grade GliomasPublication date: 13 April 2020Source: Cancer Cell, Volume 37, Issue 4Author(s): Scott Ryall, Michal Zapotocky, Kohei Fukuoka, Liana Nobre, Ana Guerreiro Stucklin, Julie Bennett, Robert Siddaway, Christopher Li, Sanja Pajovic, Anthony…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:13

AUDIOLOGY
AUD : Last 20 articlesEpidemiology and Seasonal Variation of Ménière’s Disease: Data from a Population-Based StudyIntroduction: Ménière’s disease (MD) is a disease of the inner ear. In Asian countries, there is one previous epidemiologic study that used a retrospective survey of a specific district. Previous studies have demonstrated that weather variables are strongly associated with symptom aggravation in MD. However, no study has reported on seasonal variation of MD. Methods: We conducted a retrospective…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:12

Comparison of Antioxidant Effects of the Proton Pump-Inhibiting Drugs Omeprazole, Esomeprazole, Lansoprazole, Pantoprazole, and Rabeprazole………………………..: Thus, omeprazole and esomeprazole may confer a significant dual action in gastrointestinal protection by providing potent antioxidant properties in addition to their major role as acid-suppression agents. However, further studies are essential to elucidate the mechanism behind the difference between the drugs of the same class.
Comparison of Antioxidant Effects of the Proton Pump-Inhibiting Drugs Omeprazole, Esomeprazole, Lansoprazole, Pantoprazole, and Rabeprazole: Introduction: Peptic lesions usually develop when there is an imbalance between aggressive drivers and gastro-protective mediators that guard the lining of the gastrointestinal tract. The most crucial of these mediators are antioxidants, whose loss may predispose to oxidative stress, which is believed to be the main aggravator of several diseases including peptic…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:11

Pathological and molecular detection of a rare case of cutaneous cryptococcosis in a 9-year-old horse
Pathological and molecular detection of a rare case of cutaneous cryptococcosis in a 9-year-old horse: AbstractThis report describes a rare case of primary cutaneous cryptococcosis in equines. A young gelding horse was presented with facial masses showing ulcerations and yellowish discharge. Histopathological examination of biopsy specimens showed a dermal granulomatous reaction containing neutrophils, macrophages, and giant cells. In addition, numerous spherical yeast-like organisms were clearly…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:10

Cancers
CancersCancers, Vol. 12, Pages 972: Therapeutic Strategies and Biomarkers to Modulate PARP Activity for Targeted Cancer TherapyCancers, Vol. 12, Pages 972: Therapeutic Strategies and Biomarkers to Modulate PARP Activity for Targeted Cancer Therapy Cancers doi: 10.3390/cancers12040972 Authors: Naveen Singh S. Louise Pay Snehal B. Bhandare Udhaya Arimpur Edward A. Motea Poly-(ADP-ribose) polymerase 1 (PARP1) is commonly known for its vital role in DNA damage response and repair. However, its enzymatic…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:09

Single median maxillary central incisor syndrome and variant in SMO gene associated with SHH pathway
Single median maxillary central incisor syndrome and variant in SMO gene associated with SHH pathway: Publication date: Available online 13 April 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Tomasz Zatoński, Pazdro-Zastawny Katarzyna, Morawska-Kochman Monika, Biela Mateusz, Kołtowska Anna, Rydzanicz Małgorzata, Rozensztrauch Anna, Joanna Kosińska, Dorobisz Karolina, Płoski Rafał, Robert ŚmigielCase ReportSingle median maxillary central incisor syndrome and variant…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:08

Diagnosis and management of pediatric cerebrospinal fluid leakage secondary to inner ear malformations: a report of 13 cases
Diagnosis and management of pediatric cerebrospinal fluid leakage secondary to inner ear malformations: a report of 13 cases: Publication date: Available online 13 April 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Wenmin Deng, Jie Liu, Feng Pang, Xiangmin ZhangDiagnosis and management of pediatric cerebrospinal fluid leakage secondary to inner ear malformations: a report of 13 casesAuthor links open overlay panelWenminDengJieLiuFengPangXiangminZhangDepartment of Sleep…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:07

Characterizing Emerging Canine H3 Influenza Viruses
Characterizing Emerging Canine H3 Influenza Viruses: by Luis Martinez-Sobrido, Pilar Blanco-Lobo, Laura Rodriguez, Theresa Fitzgerald, Hanyuan Zhang, Phuong Nguyen, Christopher S. Anderson, Jeanne Holden-Wiltse, Sanjukta Bandyopadhyay, Aitor Nogales, Marta L. DeDiego, Brian R. Wasik, Benjamin L. Miller, Carole Henry, Patrick C. Wilson, Mark Y. Sangster, John J. Treanor, David J. Topham, Lauren Byrd-Leotis, David A. Steinhauer, Richard D. Cummings, Jasmina M. Luczo, Stephen M. Tompkins, Kaori Sakamoto,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:06

Proceedings of the National Academy of Sciences
Retraction for Li et al., Impaired lipid metabolism by age-dependent DNA methylation alterations accelerates aging [Retractions]MEDICAL SCIENCES Retraction for “Impaired lipid metabolism by age-dependent DNA methylation alterations accelerates aging,” by Xin Li, Jiaqiang Wang, Leyun Wang, Guihai Feng, Gen Li, Meixin Yu, Yufei Li, Chao Liu, Xuewei Yuan, Guangxi Zang, Zhihuan Li, Ling Zhao, Hong Ouyang, Qingli Quan, Guangyu Wang, Charlotte Zhang, Oulan Li, Junkai…Proceedings of the National Academy…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:06

Nocturnal swallowing augments arousal intensity and arousal tachycardia [Neuroscience]
Nocturnal swallowing augments arousal intensity and arousal tachycardia [Neuroscience]: Cortical arousal from sleep is associated with autonomic activation and acute increases in heart rate. Arousals vary considerably in their frequency, intensity/duration, and physiological effects. Sleep and arousability impact health acutely (daytime cognitive function) and long-term (cardiovascular outcomes). Yet factors that modify the arousal intensity and autonomic activity remain enigmatic….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:02

Nasally delivered VEGFD mimetics mitigate stroke-induced dendrite loss and brain damage [Neuroscience]
Nasally delivered VEGFD mimetics mitigate stroke-induced dendrite loss and brain damage [Neuroscience]: In the adult brain, vascular endothelial growth factor D (VEGFD) is required for structural integrity of dendrites and cognitive abilities. Alterations of dendritic architectures are hallmarks of many neurologic disorders, including stroke-induced damage caused by toxic extrasynaptic NMDA receptor (eNMDAR) signaling. Here we show that stimulation of eNMDARs causes a…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:01

Hepatocellular Carcinoma Score and Subclassification Into Aggressive Subtypes Using Immunohistochemical Expression of p53, β-Catenin, CD133, and Ki-67
Hepatocellular Carcinoma Score and Subclassification Into Aggressive Subtypes Using Immunohistochemical Expression of p53, β-Catenin, CD133, and Ki-67: Hepatocellular carcinoma (HCC) is the most common primary hepatic malignancy in adults. Several studies have classified HCC into molecular subtypes aiming at detecting aggressive subtypes. The aim of the present study was to investigate the role of p53, β-catenin, CD133, and Ki-67 in subclassification of HCC into different aggressive subtypes and…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:01

Comparison of the Lymph2Cx Assay and Hans Algorithm in Determining the Cell-of-Origin of Diffuse Large B-Cell Lymphomas, Not Otherwise Specified
Comparison of the Lymph2Cx Assay and Hans Algorithm in Determining the Cell-of-Origin of Diffuse Large B-Cell Lymphomas, Not Otherwise Specified: In the era of precision medicine, accurate and reproducible assignment of cell-of-origin (COO) in diffuse large B-cell lymphoma patients has become important. The Lymph2Cx assay is accurately determining COO by analyzing RNA expression of 20 selected genes while the Hans algorithm based on immunohistochemistry is the most popular method for routine daily…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

09:00

Third Order Neuron In Auditory Pathway To Brain
Third Order Neuron In Auditory Pathway To Brain: neuro exam 3 auditory system. STUDY. PLAY. What nerve is associated with the …Third Order Neuron In Auditory Pathway To BrainHomeGamesPortfolioBlogInfoSearch Third Order Neuron In Auditory Pathway To BrainThe final neuron of the primary auditory pathway links the thalamus to the auditory cortex, where the message, already largely decoded during its passage through the previous neurons in the pathway, is recognized, memorized and perhaps integrated…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:50

The Primary Auditory Cortex Receives Information From All Senses
The Primary Auditory Cortex Receives Information From All Senses: Know your brain: Primary somatosensory cortex. The Auditory System – Explorable.com; What area of …The Primary Auditory Cortex Receives Information From All SensesFunctional Systems of the Cerebral Cortex. Sensory Areas.. For example, the right primary somatosensory cortex receives information from the left limbs,. primary auditIakahhoyfae Duckdns OrgThe Central Nervous System, Chapter 12 Flashcards | QuizletAuditory system – WikipediaFunctional…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:49

Anesthesia considerations of magnetic resonance imaging-guided focused ultrasound thalamotomy for essential tremor: a case series
Anesthesia considerations of magnetic resonance imaging-guided focused ultrasound thalamotomy for essential tremor: a case series: AbstractPurposeEssential tremor (ET) is a common movement disorder with disability in voluntary actions such as eating and writing. First-line treatment involves pharmacological agents, although efficacy is limited by side effects. In these patients, functional neurosurgery can be considered. Magnetic resonance imaging-guided focused ultrasound (MRgFUS) thalamotomy offers…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:48

The videoscopic view may not be significantly superior to the directly sighted peroral view during Macintosh-style videolaryngoscopy: a randomized equivalence cadaver trial
The videoscopic view may not be significantly superior to the directly sighted peroral view during Macintosh-style videolaryngoscopy: a randomized equivalence cadaver trial: AbstractPurposeVideolaryngoscopy is widely believed to give a superior view to that obtained by direct laryngoscopy. Published literature suggests this benefit extends to both hyper-angulated and Macintosh-style videolaryngoscopes. Notwithstanding, our clinical experience shows that the videoscopic view with a Macintosh-style…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:47

A Translational Physiologically Based Pharmacokinetics/Pharmacodynamics Framework of Target-Mediated Disposition, Target Inhibition and Drug–Drug Interactions of Bortezomib
A Translational Physiologically Based Pharmacokinetics/Pharmacodynamics Framework of Target-Mediated Disposition, Target Inhibition and Drug–Drug Interactions of Bortezomib: AbstractBortezomib is a potent 20S proteasome inhibitor approved for the treatment of multiple myeloma and mantle cell lymphoma. Despite the extensive clinical use of bortezomib, the mechanism of the complex time-dependent pharmacokinetics of bortezomib has not been fully investigated in context of its pharmacodynamics (PD) and…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:47

Extraction, characterization and molecular structure of bovine skin gelatin extracted with plant enzymes bromelain and zingibain
Extraction, characterization and molecular structure of bovine skin gelatin extracted with plant enzymes bromelain and zingibain: AbstractBovine skin was incubated with plant enzymes bromelain (B) and zingibain (Z) at the level of 0, 5, 10, 15, 20 and 25 unit/g of skin and gelatin was extracted at 60 °C for 6 h. Control gelatin was extracted without enzymatic pretreatment. The yield and gel strength were 17.90% and 283.35 g for the control samples and 22.26% and 160.88 g for B20 samples. The zingibain…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:46

Central Neuropathic Mechanisms in Pain Signaling Pathways: Current Evidence and Recommendations
Central Neuropathic Mechanisms in Pain Signaling Pathways: Current Evidence and Recommendations: AbstractPurposeThis is a comprehensive review of the current literature on central neuropathic pain mechanisms that is secondary to spinal cord injury. It reviews recent and seminal findings on the pathophysiology, diagnosis, and treatment and compares treatment options and recommendations.Recent FindingsNeuropathic pain (NP) is a common complication of spinal cord injury (SCI). Chronicity of NP is attributed…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:45

Remove ads


Influence of Microbiota on NSAID Enteropathy: A Systematic Review of Current Knowledge and the Role of Probiotics
Influence of Microbiota on NSAID Enteropathy: A Systematic Review of Current Knowledge and the Role of Probiotics: AbstractMicrobiota are increasingly studied, providing more precise information on their important role in physiologic processes. They also influence some pathologic processes, such as NSAID-induced enteropathy. This side effect is much more diffuse than it has been described in the past. It derives mainly from the local action of the medicines and is caused by the local binding of gram-negative…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:45

Novel Enhanced Therapeutic Efficacy of Dapoxetine HCl by Nano-Vesicle Transdermal Gel for Treatment of Carrageenan-Induced Rat Paw Edema
Novel Enhanced Therapeutic Efficacy of Dapoxetine HCl by Nano-Vesicle Transdermal Gel for Treatment of Carrageenan-Induced Rat Paw Edema: AbstractThe aim of this was to develop a well-balanced, replaceable, and patient non-infringing innovative transdermal drug delivery system “nano-vesicle transdermal gel” (NVTG) approaches for inhibiting inflammation. To consummate this objective, we developed a skin permeation nanogel system containing surface active agent along with ethanol. Carbopol 971p, hydroxypropyl…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:44

Evaluation of circulating transcript analysis (NETest) in small intestinal neuroendocrine neoplasms after surgical resection
Evaluation of circulating transcript analysis (NETest) in small intestinal neuroendocrine neoplasms after surgical resection: AbstractPurposeSurgical resection is the only effective curative strategy for small intestinal neuroendocrine neoplasms (SINENs). Nevertheless, the evaluation of residual disease and prediction of disease recurrence/progression remains a problematic issue.MethodsWe evaluated 13 SINENs that underwent surgical resection of the primary tumour and/or mesenteric mass. Patients…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:44

Comparison of different systems of ultrasound (US) risk stratification for malignancy in elderly patients with thyroid nodules. Real world experience
Comparison of different systems of ultrasound (US) risk stratification for malignancy in elderly patients with thyroid nodules. Real world experience: AbstractPurposeTo comparatively assess the performance of three sonographic classification systems, American Thyroid Association (ATA), the American College of Radiology Thyroid Imaging Reporting and Data System (ACR TI-RADS), and American Association of Clinical Endocrinologists (AACE)/American College of Endocrinology (ACE)/Associazione Medici Endocrinologi…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:44

Effect of type 2 diabetes and antihyperglycemic drug therapy on signs of tumor invasion in papillary thyroid cancer
Effect of type 2 diabetes and antihyperglycemic drug therapy on signs of tumor invasion in papillary thyroid cancer: AbstractPurposeThis retrospective study investigated the association between worrisome pathological features of papillary thyroid cancer indicative of invasion and type 2 diabetes, as well as antihyperglycemic drug therapy for diabetes.MethodsThe records of 14,167 patients who had undergone primary surgery for thyroid cancer were retrospectively reviewed and screened for concomitant…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:43

Lipschütz’s acute vulvar ulcer: a systematic review
Lipschütz’s acute vulvar ulcer: a systematic review: AbstractIn previously healthy subjects, vulvar ulcers are mostly caused by sexually transmitted microorganisms. Lipschütz’s acute vulvar ulceration, first reported in 1912, is a non-sexually acquired condition characterized by sudden onset of a few genital ulcers. We systematically review presentation, underlying causes, and disease duration of Lipschütz’s ulceration. A comprehensive source of Excerpta Medica, National Library of Medicine, and…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:43

Association between thyroid function and serum cortisol in cortisol-producing adenoma patients
Association between thyroid function and serum cortisol in cortisol-producing adenoma patients: AbstractPurposeThyroid dysfunction has been reported in hypercortisolism. Previous findings regarding changes in thyroid function due to cortisol-producing adenoma (CPA) have been inconsistent. The study aimed to investigate the association between thyroid function and excessive cortisol secretion in patients with CPA and to explore the changes in pituitary function after adrenalectomy.MethodsWe conducted…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:42

Cognitive Impairment Correlates Linearly with Mean Flow Velocity by Transcranial Doppler below a Definable Threshold
Cognitive Impairment Correlates Linearly with Mean Flow Velocity by Transcranial Doppler below a Definable Threshold: Introduction: Low cerebral blood flow can affect cognition in patients with high-grade asymptomatic internal carotid artery stenosis. Current clinical algorithms use stroke risk to determine which patients should undergo revascularization without considering cognitive decline. Although correlations between low-flow and cognitive impairment have been reported, it is not known whether…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:41

Spontaneous Intraoperative Rupture of a Large Interstitial Pregnancy: Laparoscopic Management
Spontaneous Intraoperative Rupture of a Large Interstitial Pregnancy: Laparoscopic Management: We present a case of a large interstitial pregnancy which was intraoperatively ruptured, but was eventually laparoscopically treated. The patient experienced 9 weeks of amenorrhea, and a right cornual pregnancy measuring 6 cm was diagnosed. The patient consented on having a minimal surgical treatment, and a laparoscopic right cornuotomy was decided. During surgery, and prior to any manipulation to the uterus,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:40

Novel Dimethylacetamide-Containing Formulation Improves Infraorbital Anaesthesia Efficacy in Rats with Periodontitis
Novel Dimethylacetamide-Containing Formulation Improves Infraorbital Anaesthesia Efficacy in Rats with Periodontitis: Background. To evaluate acute toxicity and local anaesthetic activity of a formulation containing a novel dimethylacetamide derivative, antioxidant, and vasoconstrictor in rats with chronic periodontitis. Methods. Novel anaesthetic dimethylacetamide-containing formulation LHT-15-32 was studied as 2% water solution. Its acute intravenous and subcutaneous toxicity was determined in…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:40

Is Tumor-Free Distance an Independent Prognostic Factor for Early-Stage Endometrioid Endometrial Cancer?
Is Tumor-Free Distance an Independent Prognostic Factor for Early-Stage Endometrioid Endometrial Cancer?: There are many studies assessing the importance of myometrial invasion using a cut-off limit as 50% of myometrial invasion for endometrial cancer, and there are a limited number of studies evaluating tumor-free distance to the serosa. To evaluate the prognostic performance of tumor-free distance and percentage of myometrial invasion in patients with stage IB endometrioid endometrial cancer, we…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:39

A Part of the Medial Branch of the Deep Peroneal Nerve Distributes the Dorsal Pedis Artery and Its Distribution Area is Close to the Acupuncture Point LR3 (Taichong)
A Part of the Medial Branch of the Deep Peroneal Nerve Distributes the Dorsal Pedis Artery and Its Distribution Area is Close to the Acupuncture Point LR3 (Taichong): Cutaneous nerves have vascular branches (VBs) that reach the arteries and are thought to be involved in arterial constriction. We aimed to examine the anatomical and histological relationship between the VBs of a cutaneous nerve in the foot and the acupuncture point LR3 (Taichong), which is a depression between the base of the first…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:39

Candida Empyema as a Red Flag for Esophageal Rupture: A Case Report and Literature Review
Candida Empyema as a Red Flag for Esophageal Rupture: A Case Report and Literature Review: Background. Candida empyema is a rare entity with an extremely high mortality rate.We present a case of multi species Candida empyema in an immunocompetent female patient with Boerhaave syndrome secondary to retching and vomiting after heroin withdrawal. This case highlights an unusual presentation of a common infection but stresses on the fact that a high index of suspicion is necessary for early identification,…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:38

The Coexistence of Colorectal Polyps in the Right Colon Increases the Malignant Risk of Laterally Spreading Tumors
The Coexistence of Colorectal Polyps in the Right Colon Increases the Malignant Risk of Laterally Spreading Tumors: Background. The coexistence of colorectal polyps with laterally spreading tumors (LSTs) is commonly observed during colonoscopy. However, there are rare studies that assess the malignant risks for LSTs with colorectal polyps, which might largely contribute to further strategies of treatment and follow-up plans in LSTs. Methods. We conducted a retrospective cohort study that enrolled…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:38

The Number of Central Lymph Nodes on Preoperative Ultrasound Predicts Central Neck Lymph Node Metastasis in Papillary Thyroid Carcinoma: A Prospective Cohort Study
The Number of Central Lymph Nodes on Preoperative Ultrasound Predicts Central Neck Lymph Node Metastasis in Papillary Thyroid Carcinoma: A Prospective Cohort Study: To evaluate the effectiveness of the number of central compartment lymph nodes (CLNs) on ultrasound (US) in predicting CLN metastasis (CLNM). We prospectively studied 309 papillary thyroid cancer (PTC) patients who underwent thyroidectomy with CLN dissection at our center from May 2017 to July 2017. The number and features of CLNs were…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:38

Ultrasound Real-Time Tissue Elastography Improves the Diagnostic Performance of the ACR Thyroid Imaging Reporting and Data System in Differentiating Malignant from Benign Thyroid Nodules: A Summary of 1525 Thyroid Nodules
Ultrasound Real-Time Tissue Elastography Improves the Diagnostic Performance of the ACR Thyroid Imaging Reporting and Data System in Differentiating Malignant from Benign Thyroid Nodules: A Summary of 1525 Thyroid Nodules: Research Article | Open AccessVolume 2020 |Article ID 1749351 | 11 pages | https://doi.org/10.1155/2020/1749351Ultrasound Real-Time Tissue Elastography Improves the Diagnostic Performance of the ACR Thyroid Imaging Reporting and Data System in Differentiating Malignant from Benign…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:37

Prognostic Significance of Thyroglobulin Antibodies in Differentiated Thyroid Cancer………………………………..not only the appearance of a significant increase in TgAb but also stable concentrations of TgAb should be regarded as a sufficient risk condition for an active search for recurrent or persistent disease. Conversely, a significant decrease in TgAb levels can represent a good prognostic sign.
Prognostic Significance of Thyroglobulin Antibodies in Differentiated Thyroid Cancer: Objective. To investigate whether variations in thyroglobulin autoantibodies (TgAb) are related to the recurrence or persistence of differentiated thyroid carcinoma (DTC) and may therefore be useful as surrogate tumor markers. Design and Methods. We retrospectively studied 98 subjects (83 women, 47 ± 15 years old) from an initial cohort of 1017 patients treated for DTC in five hospitals, with positive TgAb at any…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:33

Facial Recognition for Drunk People Using Thermal Imaging
Facial Recognition for Drunk People Using Thermal Imaging: Face recognition using thermal imaging has the main advantage of being less affected by lighting conditions compared to images in the visible spectrum. However, there are factors such as the process of human thermoregulation that cause variations in the surface temperature of the face. These variations cause recognition systems to lose effectiveness. In particular, alcohol intake causes changes in the surface temperature of the face. It is…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:32

Comparison of Conventional Keratometry and Total Keratometry in Normal Eyes
Comparison of Conventional Keratometry and Total Keratometry in Normal Eyes: Purpose. The relationship between conventional keratometry and total keratometry has not been fully investigated. This study was aimed at conventional keratometry measured with the automated keratometer and total keratometry with the corneal tomographer in ophthalmologically normal subjects. Methods. We enrolled fifty eyes of 50 consecutive subjects (,) who have no ophthalmologic diseases, other than refractive errors, with…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:31

Impact of the Italian Society of Anatomic Pathology and Diagnostic Cytology Classification of Thyroid Nodules in the Treatment of Indeterminate Follicular Lesions: Five-Year Results at a Single Center
Impact of the Italian Society of Anatomic Pathology and Diagnostic Cytology Classification of Thyroid Nodules in the Treatment of Indeterminate Follicular Lesions: Five-Year Results at a Single Center: Purpose. Aim of the study was to assess the impact of the Italian Society of Anatomic Pathology and Diagnostic Cytology (SIAPEC) classification of 2014, on the treatment of indeterminate thyroid lesions (TIR3). Methods. We retrospectively analyzed patients undergoing thyroid surgery for TIR3 lesions…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:31

Remove ads


Helicobacter pylori and Biliary Tract Cancers: A Meta-Analysis
Helicobacter pylori and Biliary Tract Cancers: A Meta-Analysis: Background. Helicobacter pylori is detected in various extragastric diseases, including biliary tract cancers. Besides, gallbladder cancers, extracholangiocarcinomas, and intracholangiocarcinomas are highly lethal cancers with limited survival due to their late diagnosis. Epidemiological data on Helicobacter pylori infection and biliary tract cancer have been contradictory. Aim. The aim of this study is to explore and evaluate the association…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:30

Spontaneous Spinal Epidural Hematoma in a Patient on Apixaban for Nonvalvular Atrial Fibrillation
Spontaneous Spinal Epidural Hematoma in a Patient on Apixaban for Nonvalvular Atrial Fibrillation: Background. With the rise in the use of direct oral anticoagulants (DOACs), more hemorrhagic complications are being encountered. Since the first description of a case of spontaneous spinal epidural hematoma (SSEH) related to the utilization of DOACs in 2012, there have been few reports describing a similar association. However, no cases so far have reported an association between SSEHs and apixaban….

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:29

Hereditary angioedema: the challenges of cross-border family investigation and treatment
Hereditary angioedema: the challenges of cross-border family investigation and treatment: Hereditary angioedema (HAE) is a rare genetic disorder characterised by recurrent swellings involving subcutaneous and submucosal tissue that can be potentially life threatening in cases involving the upper airway. In this case report, we present a Syrian refugee family with HAE who have lived in Denmark since 2014. The index patient is an 8-year-old girl diagnosed with HAE after being hospitalised in Denmark…

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,

08:22

#
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia,

Telephone consultation 11855 int 1193,